Affinity of anti-HIV antibodies in patients with asymptomatic and symptomatic HIV infection] NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

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Affinity of anti-HIV antibodies in patients with asymptomatic and symptomatic HIV infection]

Przegl Epidemiol. 1991;45(4):369-72. Unique Identifier : AIDSLINE MED/93029570
Radkowski M; Laskus T; Goch A; Babiuch L; Slusarczyk J; Zaklad Immunopatologii Instytutu Chorob Zakaznych i; Pasozytniczych Akademii Medycznej, Warszawie.

Abstract: A novel method based on the dose-response curve of antibodies was used for the assessment of the affinity of anti-HIV antibodies in 15 males with asymptomatic or symptomatic HIV infection. The subjects were followed up for a period of 1 to 5 years. No significant correlation between antibody affinity and the clinical stage of infection was observed, however, the computed affinity values increased slightly in most of the asymptomatic HIV carriers and remained relatively constant in AIDS patients. A distinct decrease of anti-HIV affinity was observed in 2 patients with advanced AIDS.
Keywords: Acquired Immunodeficiency Syndrome/*IMMUNOLOGY Adult Antibody Affinity/*IMMUNOLOGY Carrier State/*IMMUNOLOGY Comparative Study English Abstract Human HIV Antibodies/*IMMUNOLOGY HIV Antigens/*IMMUNOLOGY HIV-1/*IMMUNOLOGY Male Middle Age Poland Severity of Illness Index JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDimmunologyadultantibodyaffinity/KWDimmunologycarrierstate/KWDimmunologycomparativestudyenglishabstracthumanhivantibodies/KWDimmunologyhivantigens/KWDimmunologyhiv-1/KWDimmunologymalemiddleagepolandseverityofillnessindexjournalarticle
930130
M9311140

Copyright © 1993 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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