1993

Turnarounds : the New Haven Needle Exchange Program. [videorecording]: [United States] : Straight Shooter Production, c1991 1 videocassette (9 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9300062A; Adler S; (Producer) Documents a legal needle exchange program that is saving lives. Injecting drug use can be linked to about one third of all AIDS cases nationwide, and in New Haven the problem was even more severe. In 1990, in response to this epidemic, the state legislature passed a bill legalizing the operation of a nee
Bloodborne pathogens standard for the laboratory. [videorecording]: [Tucson, Ariz.] : Medfilms, c1992 1 videocassette (9 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9300030A; Reeter AK
In the midst of winter. [videorecording]: [Seattle, Wash.] : AIDS Video Project, c1992 1 videocassette (58 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9300104A; (Producer) This video brings us voices from the frontlines of the AIDS epidemic and offers lessons on facing the inevitable result of this fatal disease. Viewers are introduced to a diverse group of individuals who share their thoughts on issues of life, death, and death s aftermath.
Summary of state statutes which specifically mention acquired immune deficiency syndrome.: [Washington, D.C] : Congressional Research Service, Library of Congress, [1987] 16 p (CRS report for Congress ; 87-239 A) Unique Identifier : AIDSLINE CAT/9217118; Wolfe MA
The:Impact of AIDS in the Native American community : report.: Lake Andes, S.D. : Native American Women's Health Education Resource Center, [1988] 43 p Unique Identifier : AIDSLINE CAT/9300140; Easthope T
AIDS : a fact of life.: Pinelands, Cape Town : Maskew Miller Longman, 1988 x, 102 p. : ill Unique Identifier : AIDSLINE CAT/9300368; Jefferies G
[AIDS : Fakten und Konsequenzen : Zwischenbericht der Enquete-Kommission des 11. Deutschen Bundestages Gefahren von AIDS und wirksame Wege zu ihrer Eindammung.]: Wirksame Wege zu Ihrer Eindammung Bonn : Deutscher Bundestag, Referat Offentlichkeitsarbeit, 1988 283 p. : ill (Zur Sache ; 3/88) Unique Identifier : AIDSLINE CAT/9300369
AIDS, the legal issues : discussion draft of the American Bar Association, AIDS Coordinating Committee.: Washington, D.C. : American Bar Association, AIDS Coordinating Committee, c1988 iii, 252 p Unique Identifier : AIDSLINE CAT/9300370
Gays/justice : a study of ethics, society, and law.: New York : Columbia University Press, c1988 ix, 357 p Unique Identifier : AIDSLINE CAT/9300461; Mohr RD
[SIDA : mejor es prevenir.] 1. ed.: San Cristobal : Edo. Tachira, [1988] 69 p. : ill Unique Identifier : AIDSLINE CAT/9301069; Mansilla J
California AIDS update. Apr. 4, 1988-v. 3, no. 9 (Oct. 1990).: Sacramento, CA : The Office, [1988-1990] 3 v. : ill Unique Identifier : AIDSLINE CAT/9300791
AIDS and HIV infection statement.: [Sydney, N.S.W.] : AIDS Bureau, NSW Dept. of Health, [1989-] v (AIDS and HIV infection statement ; no. 1, etc.) Unique Identifier : AIDSLINE CAT/9217012
Asian women and AIDS : report of an inter-agency meeting : New Delhi, 1 December 1988.: [New Delhi] : World Health Organization, South-East Asia Region, [1989] 15 p Unique Identifier : AIDSLINE CAT/9217009
The:Bi-line kit : a Queensland AIDS Council project. 1st ed.: [Brisbane] : Queensland AIDS Council, 1989 63, 34 p. : ill Unique Identifier : AIDSLINE CAT/9300380; Chauvin A; Moran K
[AIDS : Fakten und Konsequenzen : Endbericht der Enquete-Kommission des 11. Deutschen Bundestages Gefahren von AIDS und wirksame Wege zu ihrer Eindammung.]: Wirksame Wege zu Ihrer Eindammung Bonn : Deutscher Bundestag, Referat Offentlichkeitsarbeit, 1990 800 p. : ill., ports (Zur Sache ; 13/90) Unique Identifier : AIDSLINE CAT/9300049
Guidance for clinical health care workers : protection against infection with HIV and hepatitis viruses : recommendations of the Expert Advisory Group on AIDS.: London : HMSO, 1990 52 p. : ill Unique Identifier : AIDSLINE CAT/9300118
Psychosocial aspects of HIV and AIDS and the evaluation of preventive strategies : report on a WHO meeting, Lisbon, 28 May-1 June 1990.: Copenhagen : World Health Organization, Regional Office for Europe, c1990 45 p (WHO regional publications. European series, ISSN 0378-2255 ; no. 36) Unique Identifier : AIDSLINE CAT/9300257
AIDS education : public school programs require more student information and teacher training : report to the chairman, Committee on Governmental Affairs, U.S. Senate.: Washington, D.C. : U.S. General Accounting Office, [1990] 45 p. : ill Unique Identifier : AIDSLINE CAT/9300366
AIDS education : programs for out-of-school youth slowly evolving : report to the chairman, Committee on Governmental Affairs, U.S. Senate.: Washington, D.C. : U.S. General Accounting Office, [1990] 19 p Unique Identifier : AIDSLINE CAT/9300367
Arizona responds to AIDS. Vol. 1, no. 1 (winter 1990)-: Phoenix, Ariz. : Arizona Dept. of Health Services, Office of Health Promotion & Education, 1990- v. : ill., ports Unique Identifier : AIDSLINE CAT/9300766
Notes from the underground : the PWA Health Group newsletter.: New York, NY : People with AIDS Working for Health, Inc., v Unique Identifier : AIDSLINE CAT/9300979
[Niedrigschwellige Angebote im Rahmen des Modells Drogen und AIDS = Outreach work in the Demonstration project Drugs and AIDS.]: Munchen : Institut fur Therapieforschung, 1990 65, 2 p. : ill (IFT-Berichte ; Bd. 55) Unique Identifier : AIDSLINE CAT/9300978; Schumann J
The:Italian research project on AIDS : the role of the Istituto superiore di sanita.: Roma : Il Istituto, [1991] 22 p Unique Identifier : AIDSLINE CAT/9217061
[Grossmodell Gesundheitsamter, AIDS : Abschlussbericht der wissenschaftlichen Begleitung : Darstellung und Bewertung von Modelleistungen.]: Kiel : Institut fur Gesundheits-System-Forschung, 1991 1 v. (various pagings) : ill (Schriftenreihe / Institut fur Gesundheits-System-Forschung ; Bd. 38) Unique Identifier : AIDSLINE CAT/9300116; Thoben I
[Die:Auswirkungen von AIDS im Privatversicherungsrecht : eine Untersuchung uber AIDS-spezifische Probleme im Kranken-, Lebens-, und Haftpflichtversicherungsrecht.]: Frankfurt am Main ; New York : Peter Lang, c1991 xviii, 160 p (Versicherungsrechtliche Studien, ISSN 0178-4382 ; Bd. 19) Unique Identifier : AIDSLINE CAT/9300769; Thies C
Women and AIDS/HIV : a review of community based HIV prevention programs funded by the United States Conference of Mayors.: Washington, D.C. (1620 Eye St. N.W., Washington 20006) : United States Conference of Mayors, c1991 22 p (HIV education case studies ; no. 3 (May 1991)) Unique Identifier : AIDSLINE CAT/9301097; Jones P
Theory and practice of HIV counselling : a systemic approach.: London ; New York, NY : Cassell, 1992 192 p. : ill Unique Identifier : AIDSLINE CAT/9217120; Bor R; Miller R; Goldman E
[Aids und Recht : Dokumentation eines interdisziplinaren Symposiums in Marburg vom 29. September bis 1. Oktober 1989.]: Stuttgart : Boorberg, c1992 244 p (Marburger Schriften zum offentlichen Recht ; Bd. 5) Unique Identifier : AIDSLINE CAT/9300028; Gallwas H
[HIV-Betroffene und ihr Umfeld : Ergebnisse aus psychosozialer Forschung und Praxis.]: Berlin ; New York : Springer-Verlag, c1992 xi, 203 p. : ill Unique Identifier : AIDSLINE CAT/9300879; Ermann M
[Systeme nerveux et infection par le V.I.H.]: Paris : Masson, 1992 ix, 102 p. : ill (ABC de medecine) Unique Identifier : AIDSLINE CAT/9301067; Thomas P
Immunodeficiencies.: Chur, Switzerland ; Philadelphia, Pa., USA : Harwood Academic Publishers, c1993 ix, 761 p., [4] p. of plates : ill Unique Identifier : AIDSLINE CAT/9300882; Rosen FS; Seligmann M
AIDS epidemiology : a quantitative approach.: New York : Oxford University Press, 1994 ix, 354 p. : ill (Monographs in epidemiology and biostatistics 22) Unique Identifier : AIDSLINE CAT/9217013; Brookmeyer R; Gail MH
Now dare everything : tales of HIV-related psychotherapy.: New York : Haworth Press, c1994 xi, 332 p. : ill (Haworth social work practice) Unique Identifier : AIDSLINE CAT/9300211; Dansky S
Cervical carcinoma and the human immunodeficiency virus (HIV) (Meeting abstract).: International Cervical Cancer Symposium. November 26-30, 1991, Saint Lucia, West Indies, p. 21, 1991.. Unique Identifier : AIDSLINE ICDB/93685946; Fruchter RG; Maiman M; Remy JC; Serur E; Kelly P; State University of New York, Brooklyn, NY; Since 1987, we have studied the characteristics and response to therapy of cervical neoplasia in HIV-infected women at a public hospital in Brooklyn, NY. At least one half of HIV-infected women have abnormal cytology and cervical intraepithelial neoplasia (CIN) on biopsy. Of invasive cervical cancer (ICC) patients (pt
Genetic structure and regulation of HIV.: Harvard AIDS Inst Ser; 1:1-537 1991. Unique Identifier : AIDSLINE ICDB/93686276; Anonymous; No affiliation given; The most profound theme to emerge from studies of the human retroviruses is that regulation of gene expression can be achieved via binding of regulatory proteins to specific regions of the viral RNA. Two of the essential regulatory proteins of HIV-1, the transactivator gene (tat) and the regulator of virion protein-ex
HIV-1 transactivator.: Harvard AIDS Inst Ser; 1:43-310 1991. Unique Identifier : AIDSLINE ICDB/93686277; Anonymous; No affiliation given; Transcription of the HIV genome proceeds in distinct kinetic phases. Initially, short, multiply spliced mRNAs, which encode the viral regulatory proteins tat and rev, are expressed, whereas, late in infection production switches to full-length, unspliced transcripts that act both as the virion RNA and the mRNA for the
The HIV long terminal repeat.: Harvard AIDS Inst Ser; 1:391-435 1991. Unique Identifier : AIDSLINE ICDB/93686279; Anonymous; No affiliation given; HIV-1 is subject to transcriptional regulation. The HIV promoter functions poorly in most cell types studied. For example, the HIV-1 long terminal repeat (LTR) directs a much lower level of heterologous gene expression in human CD4+ lymphocytes than does the LTR of the Rous sarcoma virus, an avian retrovirus. Sequence
Other HIV regulatory genes.: Harvard AIDS Inst Ser; 1:437-71 1991. Unique Identifier : AIDSLINE ICDB/93686280; Anonymous; No affiliation given; The human immunosuppressive virus (HIV) and simian immunosuppressive virus (SIV) possess surprisingly complex genomes. In addition to three structural genes, gag, pol and env, which commonly are found in replication-competent retroviruses, HIV-1 has at least six regulatory genes in its genome. Two of these genes, tat
Retroviral envelope glycoprotein genes.: Harvard AIDS Inst Ser; 1:473-570 1991. Unique Identifier : AIDSLINE ICDB/93686281; Anonymous; No affiliation given; Various aspects of the life cycle of HIV are reviewed, including molecular determinants of clinical latency (cellular activation and HIV replication [activation and HIV DNA synthesis, activation and transcription of HIV genes], the question of whether viral genes are involved in clinical latency, self-limited HIV repl
HIV-1 infection of dendritic cells.: Harvard AIDS Inst Ser; 1:511-25 1991. Unique Identifier : AIDSLINE ICDB/93686282; Anonymous; No affiliation given; The clinical characteristic of HIV-1 infection is the depletion of CD4+ T cells despite the relatively low frequency (10(-2) to 10(-4)) of infected CD4+ T cells early in the disease. One explanation for the T-cell loss is an early direct cell lysis of stimulated and infected T cells. Another mechanism proposed for the
CEOP in the treatment of systemic non-Hodgkin's lymphoma in AIDS (Meeting abstract).: Clinical Oncology Society of Australia Inc. Annual Scientific Meeting: From Laboratory to Clinic--an Integrated Approach to Cancer Research and Therapy. December 4-6, 1991, Sydney, Australia, p. 121, 1991.. Unique Identifier : AIDSLINE ICDB/93686695; Milliken S; Goldstein D; Cooper D; Friedlander M; Penny R; Kelleher A; St. Vincent's Hospital, Sydney, New South Wales 2010, Australia; The development of NHL in AIDS conveys a poor prognosis with less than 10% of patients (pts) surviving beyond 2 yr. However, these aggressive tumors often require systemic chemotherapy to bring about effective palliation. In the last year, we have investigated the combination of cyclophosphamide 750 mg/m2, epirubicin
The economic impact of the HIV epidemic in the United States.: AIDS Updates; 4(5):1-12 1991. Unique Identifier : AIDSLINE ICDB/93686724; Scitovsky AA; Palo Alto Medical Foundation, Res. Inst., Palo Alto, CA; This article gives a brief survey of the demographics of AIDS incidence in the United States , from the first reports by the Centers for Disease Control in mid-1981 through February 1991, and a discussion of the direct medical care costs of the HIV epidemic (costs). These topics are add
Immunologic status of patients with oral cancers: quantitation of helper and suppressor cells using monoclonal antibodies (Meeting abstract).: Second International Congress on Oral Cancer. December 2-5, 1991, New Delhi, India, p. 49, 1991.. Unique Identifier : AIDSLINE ICDB/93686950; Thomas S; Nath I; Dhawan IK; University Coll. of Medical Sciences, Shahdara, Delhi, India; Interest in an immunologic basis for the etiology, progression and treatment of malignant disease has prompted considerable investigation into the status of humoral and cellular immune mechanisms in cancer patients (pts). In this study, we have quantitated T cells and their subpopulations (helper and suppressor cells)
The role of alpha interferon in the regulation of natural killer cell cytolytic activity in HIV-1 seropositive individuals.: Diss Abstr Int [B]; 52(7):3516 1992. Unique Identifier : AIDSLINE ICDB/93682456; Haberzettl CA; Rutgers, the State Univ. of New Jersey, New Brunswick, NJ; Spontaneous natural killer (NK) cell cytolytic activity is generally agreed to be decreased in full-blown AIDS patients (pts), but reports on the status of NK activity during the critical period prior to the development of full-blown AIDS are not in agreement. Our studies evaluated the quantitative and functional acti
Functional and immunological characterization of the simian immunodeficiency virus envelope glycoprotein.: Diss Abstr Int [B]; 52(7):3517 1992. Unique Identifier : AIDSLINE ICDB/93682468; Planelles V; Univ. of California, Davis; Retroviral envelope glycoproteins interact with cell receptors and are targets for antiviral immune responses in infected hosts. SIV(mac) is a T-lymphocytopathic lentivirus which causes an AIDS-like disease in rhesus macaques. The envelope gene of SIV(mac) encodes a precursor glycoprotein (gp160) which is cleaved into
Quantitation and characterization of human immunodeficiency virus nucleic acid in AIDS patients by using the polymerase chain reaction.: Diss Abstr Int [B]; 52(7):3415 1992. Unique Identifier : AIDSLINE ICDB/93682470; Dickover RE; Univ. of California, Davis; The objectives of this research are to develop and implement a quantitative polymerase chain reaction (PCR) assay for the study of human immunodeficiency virus (HIV) DNA in AIDS patients (pts). PCR provides us with a method that is both exquisitely sensitive and specific and, thus, perfectly suited to the characteriza
Macrophage tropism of simian immunodeficiency virus.: Diss Abstr Int [B]; 52(7):3413 1992. Unique Identifier : AIDSLINE ICDB/93682471; Banapour B; Univ. of California, Davis; Simian immunodeficiency virus (SIV) is the causative agent of a disease in rhesus macaques which closely parallels acquired immunodeficiency syndrome (AIDS) in humans infected with human immunodeficiency virus (HIV). These primate viruses are members of the Lentivirinae subfamily of retroviruses. Lentivirus infection
Judgments of professional psychologists about patients with the acquired immunodeficiency disease (AIDS) virus and terminal cancer.: Diss Abstr Int [B]; 52(7):3897 1992. Unique Identifier : AIDSLINE ICDB/93682477; Barkin SL; Hofstra Univ.; Researchers have sought to identify the value-relevant variables that might bias diagnosis, prognosis, and outcome. Abramowitz and Dokecki (1977), have identified a series of biases elicited by social and cultural variables such as gender, race, and social class. Other sources of bias related to patient (pt) character
Studies on the structure and expression of the human CD4 gene.: Diss Abstr Int [B]; 52(7):3393 1992. Unique Identifier : AIDSLINE ICDB/93682486; Wong GT; Cornell Univ. Medical Center; The human CD4 protein is a 55-kD glycoprotein predominantly expressed on the cell surface of thymocytes and T-cells. CD4 functions in these cells to increase the affinity of a T-cell receptor (TcR) for antigen bound to major histocompatibility complex (MHC) class II proteins. CD4 also acts as a coreceptor, complexing
Anti-HIV nucleoside analogs and mitochondria.: Diss Abstr Int [B]; 52(7):3543 1992. Unique Identifier : AIDSLINE ICDB/93682498; Chen C; Univ. of North Carolina at Chapel Hill; Human immunodeficiency virus (HIV) is believed to be the causative agent of acquired immunodeficiency syndrome (AIDS). The incidence of this fatal disease has increased in recent years. Efforts have been taken to develop effective AIDS therapies. One strategy is to inhibit the viral reverse transcriptase which is esse
tat and rev regulation of human immunodeficiency virus type 1 envelope protein expression in a SV40 late replacement vector.: Diss Abstr Int [B]; 52(7):3438 1992. Unique Identifier : AIDSLINE ICDB/93682501; Lu X; State Univ. of New York at Buffalo; The Human Immunodeficiency Virus type 1 (HIV-1), contains several genes encoding regulatory proteins in addition to the structural protein genes present in all known retroviruses. Two of them, tat and rev, are encoded by the same region of the viral genome. The genes for these proteins contain two overlapping exons wh
Cloning and expression of an HTLV gag-related autoantigen (Meeting abstract).: FASEB J; 6(4):A1119 1992. Unique Identifier : AIDSLINE ICDB/93687051; Banki K; Brachmann J; Hung C; Mattson D; Ablonczy E; Perl A; RPMI, Buffalo, NY 14263; We cloned a second human T-cell leukemia virus-related endogenous sequence (HRES-2), which is distinct from HRES-1 (NAR 17:6841-54, 1989). An HRES-2 cDNA was expressed in a prokaryotic vector. Recombinant HRES-2 protein was used to generate specific antibodies. HRES-2-specific antibodies identified the native protein,
Selective expression of IL-10, IFN-gamma and GM-CSF in ovarian cancer biopsies (Meeting abstract).: FASEB J; 6(4):A1151 1992. Unique Identifier : AIDSLINE ICDB/93687071; Pisa EK; Pisa P; Halapi E; Gerdin E; Hising C; Bucht A; Gerdin B; Kiessling R; Karolinska Inst., Danderyds Hosp., Stockholm, Sweden; The variable clinical response seen with most cancer immunotherapy suggests that individual patients have very different immunological mechanisms involved in the pathophysiology of their specific malignancy. These can include important differences in tumor antigens on the malignant cells, as well as the specific immun
Modulation of CD8+ T-cell differentiation state following stimulation with interleukin-7 (IL-7) (meeting abstract).: FASEB J; 6(5):A1698 1992. Unique Identifier : AIDSLINE ICDB/93687598; Feeney LA; Fredericks KH; Harvey SE; Okarma TB; Moody DJ; Applied Immune Sciences, Inc., Menlo Park, CA; Extracorporeal manipulation of autologous T cells is used in clinical trials for the treatment of cancer and AIDS. Most of these approaches depend upon the ex vivo production of large numbers (greater than 10(10)) of effector cells. Two key improvements that can be made to improve the efficiency of this process would
Expression of a peptide related to the murine mammary tumor virus (MTV) but not to the human MTV in BALB/c cells of the B lineage (Meeting abstract).: FASEB J; 6(5):A1706 1992. Unique Identifier : AIDSLINE ICDB/93687601; Lopez-Cepero M; Keydar I; Dion A; Riley R; Lopez DM; Dept. of Microbiology and Immunology, Univ. of Miami Sch. of; Medicine, Miami, FL 33136; Splenic B cells from BALB/c mice express murine MTV (MMTV)-related protein on their cell membranes. This has been demonstrated by flow cytometry and by Western blots, using polyclonal anti-MMTV antibody. This protein has a mol wt of 68 kD and shares antigenic moieties with the env proteins gp52 and gp36. BALB/c bone m
Variables in HIV-positive patients that serve to predict response to whole-body hyperthermia.: Diss Abstr Int [B]; 53(3):1287 1992. Unique Identifier : AIDSLINE ICDB/93687834; Parkinson JD; Univ. of Tennessee; This study utilized a small population of HIV-positive, symptomatic patients (pts) who were being treated with whole-body hyperthermia for Kaposi s sarcoma. An effort was made to identify any trends in the properties of the pts that might aid in the prediction of the HIV response to hyperthermia. This would allow for
Role of nuclear factor-kB in the regulation of c-myc gene transcription.: Diss Abstr Int [B]; 53(3):1192 1992. Unique Identifier : AIDSLINE ICDB/93687843; Duyao MP; Boston Univ.; The c-myc proto-oncogene has been implicated in cell proliferation, differentiation, and neoplasia. Its expression is largely regulated at the level of transcription. I have mapped several regions upstream of the murine c-myc promoter which interact with nuclear proteins from the murine B-cell lymphoma cell line WEHI
Development of a tRNA based transcription system to render cells resistant to viral replication.: Diss Abstr Int [B]; 52(7):3444 1992. Unique Identifier : AIDSLINE ICDB/93682490; Sullenger BA; Cornell Univ. Medical Center; Inhibition of gene expression via antisense RNA requires the synthesis of a considerable excess of antisense RNA over sense RNA, and with a few exceptions, RNA polymerase II-based transcription units are inadequate to generate such an excess of antisense RNA. Therefore, we have explored the use of RNA polymerase III-b
A structural and functional characterization of the 2-5A synthetase/RNase L antiviral pathway and its role in HIV-1 regulation: the pivotal role of 2-5A.: Diss Abstr Int [B]; 52(7):3590 1992. Unique Identifier : AIDSLINE ICDB/93682505; Sobol RW; Temple Univ.; The mechanism of 2-5A synthesis and the binding and activation processes of RNase L were characterized using structurally and stereochemically modified analogs of ATP and 2-5A. It was established that the mechanism of 2-5A synthesis proceeds by inversion of configuration and that the 2 ,5 -phosphorothioate dimer can a
DNA polymerase activity assays: new techniques and applications in tumor and viral diseases, notably HIV-infection.: Diss Abstr Int [C]; 53(2):289 1992. Unique Identifier : AIDSLINE ICDB/93686581; Neumuller M; Uppsala Universitet, Sweden; DNA polymerase (DNA-pol) activity was detected in serum samples of patients (pts) with leukemia, vitamin B12 deficiency or cytomegalovirus infection, using a standard assay technique based on detection of [3H]dTMP incorporated into DNA. DNA-pol activity was only detected in serum s
Limited variability of the TCR V beta (VB) chains in the CD8+57+ T cells expanded after bone marrow transplantation (BMT) but not HIV infection (Meeting abstract).: FASEB J; 6(4):A1138 1992. Unique Identifier : AIDSLINE ICDB/93687057; Gorochov G; Debre P; Leblond V; Sadat-Sowti B; Sigaux F; Autran B; Lab. of Cellular Immunology, Dept. of Hematology, Hopital; Pitie-Salpetriere, Paris, France; A major expansion of the CD8+57+ peripheral blood T lymphocytes (ranges 15-60% PBL; normal values: 7 +/- 5%) is frequent after transplantation or viral infection. We observed oligoclonal TCR rearrangements in CD8+57+ T cells from 8/9 BMT leukemia-free patients (pts), but not in the control, autologous CD57- T cells. T
Lack of evidence for the presence of human immunodeficiency virus type 1-related sequences in patients with Graves' disease.: Thyroid. 1991 Winter;1(4):307-14. Unique Identifier : AIDSLINE MED/93044563; Tominaga T; Katamine S; Namba H; Yokoyama N; Nakamura S; Morita S; Yamashita S; Izumi M; Miyamoto T; Nagataki S; First Department of Internal Medicine, Nagasaki University School; of Medicine, Japan.; The pathogenesis of human autoimmune diseases, including Graves disease, remains to be elucidated. Recently, Ciampolillo et al. proposed that human immunodeficiency virus type 1 (HIV-1)-related retroviruses were involved in Graves disease. Using Southern blot analysis, they found specific integration of exogenous se
Synthesis of antisense oligodeoxyribonucleotides and their anti-HIV activity.: Nucleic Acids Symp Ser. 1991;(25):103-4. Unique Identifier : AIDSLINE MED/93065239; Gug-Kim S; Suzuki Y; Nakashima H; Yamamoto N; Takaku H; Department of Industrial Chemistry, Chiba Institute of; Technology, Japan.
Synthesis of the 2',3'-dideoxynucleoside derivatives of the specific binding peptide part of CD4.: Nucleic Acids Symp Ser. 1991;(25):189-90. Unique Identifier : AIDSLINE MED/93065286; Uchiyama T; Yoshino H; Takemoto M; Achiwa K; School of Pharmaceutical Sciences, University of Shizuoka, Japan.
Nucleoside analogs with vinyl fluoride structure; synthesis and anti-HIV activity.: Nucleic Acids Symp Ser. 1991;(25):191-2. Unique Identifier : AIDSLINE MED/93065288; Nakayama T; Asai T; Okazoe T; Suga A; Morizawa Y; Yasuda A; Research Center, Asahi Glass Co. Ltd, Yokohama, Japan.
Synthesis and anti-HIV activity of carbovir and related carbocyclic nucleosides.: Nucleic Acids Symp Ser. 1991;(25):193-4. Unique Identifier : AIDSLINE MED/93065289; Vince R; Department of Medicinal Chemistry, College of Pharmacy,; University of Minnesota, Minneapolis 55455-0343.; (+/-) Carbocyclic 2 ,3 -didehydro-2 ,3 -dideoxyguanosine (Carbovir) is an antiretroviral agent which is undergoing preclinical evaluation for the treatment of AIDS. Its hydrolytic stability and its ability to inhibit infectivity and replication of HIV in T-cells at concentrations of approximately 400-fold below toxic
Synthesis of purine bases having a di(hydroxymethyl)cyclopentenyl group by means of high-pressure reaction and their anti-HIV activity.: Nucleic Acids Symp Ser. 1991;(25):5-6. Unique Identifier : AIDSLINE MED/93065306; Katagiri N; Nomura M; Sato H; Tameda C; Kurimoto A; Arai S; Toyota A; Kaneko C; Pharmaceutical Institute, Tohoku University, Sendai, Japan.; The 1 - and 5 -hydroxymethyl derivatives of carbovir and related purine derivatives were synthesized from 5-hydroxymethylcyclopentadiene. The anti-HIV activity evaluation of these compounds has revealed that 9-(c-4,t-5-dihydroxymethylcyclopent-2-en-r-1-yl)-9H-adenine is a prospective chemotherapeutic agent against AID
Mechanisms of inhibitions of DNA polymerase gamma by nucleotide analogues having anti-HIV activities.: Nucleic Acids Symp Ser. 1991;(25):79-80. Unique Identifier : AIDSLINE MED/93065322; Izuta S; Saneyoshi M; Sakurai T; Suzuki M; Kojima K; Yoshida S; Laboratory of Cancer Cell Biology, Nagoya University School of; Medicine, Japan.; Inhibition mechanisms of 5 -triphosphates of 3 -azido-3 -deoxythymidine (AZT-TP) and 3 -deoxythymidine (ddTTP) on extensively purified DNA polymerase gamma from bovine testes were examined by analysis of the products synthesized on singly primed M13mp18 single-stranded DNA or synthetic oligonucleotide template-primer
[Indirect immunofluorescence with monoclonal antibodies in the diagnosis of Pneumocystis carinii. Preliminary report]: Rev Med Chil. 1991 Mar;119(3):293-4. Unique Identifier : AIDSLINE MED/93067737; Weitz JC; Astorga B; Laboratorio de Referencia de Parasitologia, Instituto de Salud; Publica, Santiago de Chile.; We compared traditional methods based on argentic metamine and toluidine blue staining vs recently introduce techniques based on immunofluorescence for monoclonal antibodies in the diagnosis of P. carinii. Fifty samples were analyzed: 29 (58%) were negative by all method. Of the remaining 21.72% were positive for immu
[Ethical aspects related to AIDS]: Rev Med Chil. 1991 Mar;119(3):344-9. Unique Identifier : AIDSLINE MED/93067747; Aguilera P; An alarming number of cases of the AIDS syndrome have been detected worldwide, and greater extension of the disease is expected in the near future. Ethical aspects are important in relation to AIDS, since freedom of human behavior is involved in most cases. Ethical aspects of prevention, diagnosis and treatment of AID
Synthesis and structure-activity relationships of 2',3'-dideoxypurine nucleosides as potential antiretroviral agents.: Nucleic Acids Symp Ser. 1991;(25):91-2. Unique Identifier : AIDSLINE MED/93065329; Kojima E; Shirasaka T; Machida M; Yoshioka H; Murakami K; Mitsuya H; Research Laboratory of Bioresources, Sanyo-Kokusaku Pulp Co. Ltd,; Iwakuni, Japan.; In order to study the structure-activity relationships of 2 ,3 -dideoxypurine nucleosides as potential anti-retroviral agents, various purine derivatives have been synthesized and tested against rous sarcoma virus (RSV) in chick embryo fibroblast (CEF) cells, and against human immunodeficiency virus (HIV) in human CD4
Ribozyme-mediated cleavage of an HIV-1 gag RNA: the effects of nontargeted sequences and secondary structure on ribozyme cleavage activity.: Antisense Res Dev. 1991 Summer;1(2):173-86. Unique Identifier : AIDSLINE MED/93044231; Taylor NR; Rossi JJ; Department of Molecular Genetics, Beckman Research Institute of; the City of Hope, Duarte, CA 91010.; Catalytic antisense RNAs, or ribozymes, have great potential as inhibitors of gene expression and as antiviral therapeutic agents. The major advantage of ribozymes versus standard antisense RNAs is their catalytic capability, enabling these RNAs to cleave multiple substrates. We have been investigating the antiviral a
Estimation of whole-body RNA catabolism based on the urinary modified nucleoside levels of cancer and AIDS patients.: Nucleic Acids Symp Ser. 1991;(25):125-6. Unique Identifier : AIDSLINE MED/93065251; Nakano K; Nakao T; Schram KH; Hammargren WM; PL Comprehensive Research Institute, Osaka, Japan.; From the relationship between the molar ratio of nucleosides calculated stoichiometrically from modified nucleoside occurrences in major RNA species and the proportion of rRNA to all of RNA contents in average tissues, the increase of rRNA contents in cancer tissues growing rapidly was found. Thus, we found that selec
Inhibitory effect of N3-methyl derivative of 3'-azido-3'-deoxythymidine 5'-triphosphate on the activity of HIV-1 reverse transcriptase.: Nucleic Acids Symp Ser. 1991;(25):27-8. Unique Identifier : AIDSLINE MED/93065293; Nakane H; Suzuki A; Nakata Y; Kitade Y; Hirota K; Maki Y; Ono K; Laboratory of Viral Oncology, Aichi Cancer Center Research; Institute, Nagoya, Japan.; N3-Methyl derivative of 3 -azido-3 -deoxythymidine 5 -triphosphate (Me-AZTTP) showed a potent inhibitory effect on HIV-1 reverse transcriptase using MS2 phage RNA as the template. The inhibition mechanism of MeAZTTP was noncompetitive with respect to any of the template MS2 RNA, dATP and dCTP. On the other hand, MeAZT
Influence of the level of dietary ethanol in mice with murine AIDS on resistance to Streptococcus pneumoniae.: Alcohol Alcohol. 1992 Jul;27(4):345-52. Unique Identifier : AIDSLINE MED/93039023; Shahbazian LM; Darban HR; Darban JR; Stazzone AM; Watson RR; Department of Family and Community Medicine, University of; Arizona, Tucson 85724.; Chronic ethanol consumption impairs cellular immune functions. This may explain the increased occurrence of various opportunistic infections in heavy ethanol users. Immunological alterations associated with Acquired Immune Deficiency Syndrome (AIDS) also permit more opportunistic infections. In this study, we used a m
Status and trend of HIV-1 infection and AIDS in Taiwan, December, 1991.: Asian Pac J Allergy Immunol. 1992 Jun;10(1):65-8. Unique Identifier : AIDSLINE MED/93039111; Chang PY; Lin KC; Chuang CY; Wang CR; Chen MY; Hsieh WC; Wang GR; Cheng DL; Chang KS; Ko YC; et al; AIDS Advisory Committee, Department of Health, Executive Yuan,; Taiwan, ROC.; From May 1, 1985 to December 31, 1991, a total of 4,962,707 serum samples from 8 population groups in Taiwan were tested for anti-human immunodeficiency virus type 1 (anti-HIV-1). In total, 256 samples were seropositive; of these in
AIDS and arthroscopic surgery.: Arthroscopy. 1992;8(3):279-86. Unique Identifier : AIDSLINE MED/93039131; Cannon WD Jr; Vittori JM; Department of Orthopaedic Surgery, University of California, San; Francisco School of Medicine 94143-0728.; There are an estimated 8 to 10 million people worldwide infected with human immunodeficiency virus (HIV). The true extent of infection in the population is unknown, and many are unaware of their HIV status. Arthroscopic and arthroscopically assisted surgery is less invasive and bloody than other orthopaedic procedures
Arteriovenous fistula after arthroscopic synovectomy in a patient with haemophilia.: Arthroscopy. 1992;8(3):373-4. Unique Identifier : AIDSLINE MED/93039146; Cohen B; Griffiths L; Dandy DJ; Department of Orthopaedic Surgery, Addenbrooke's Hospital,; Cambridge, England.; Arteriovenous fistula is a rare complication of arthroscopy. We report a human immunodeficiency virus-positive person with haemophilia who 19 months after an arthroscopic synovectomy of the knee presented with increasingly frequent haemarthroses and a palpable thrill over the knee. Angiography confirmed an arterioveno
Induction of anti-DNA IgG and IgE antibodies in BALB/c mice.: J Autoimmun. 1992 Oct;5(5):653-63. Unique Identifier : AIDSLINE MED/93039270; Namboodiri MS; Nagpal S; Rao PV; Department of Biochemistry, Indian Institute of Science,; Bangalore.; Immunization of BALB/c mice with denatured DNA (dnDNA)-methylated bovine serum albumin (MBSA) complex along with aluminium hydroxide gel as adjuvant, resulted in the induction of anti-DNA antibodies of both IgG and IgE isotypes demonstrable by avidin-biotin micro enzyme-linked immunosorbent assay (ELISA) and solid pha
Antibodies against p24 of HIV-1 in patients with systemic lupus erythematosus?: Viral Immunol. 1992 Fall;5(3):229-31. Unique Identifier : AIDSLINE MED/93039297; Herrmann M; Baur A; Nebel-Schickel H; Vornhagen R; Jahn G; Krapf FE; Kalden JR; Department of Medicine III, University Erlangen, Germany.; The involvement of retroviruses in the etiopathogenesis of autoimmunity is discussed. Recently antibodies against p24 of HIV-1 were described in patients from Texas with SLE. Therefore we investigated the presence of these antibodies in our SLE collective (German caucasians and blacks from Michigan) employing ELISA an
Coping with substance abuse: a many-sided task.: World Health Forum. 1992;13(2-3):101-11; discussion 112-27. Unique Identifier : AIDSLINE MED/93039299; Wodak A; Alcohol and Drugs Services, St Vincent's Hospital, Sydney, New; South Wales, Australia.; Steady progress is being made towards understanding the use of drugs for non-therapeutic purposes. The associated problems are increasingly regarded as having psychological, biological and social dimensions. There is a growing acceptance that the hazardous consumption of alcohol and other drugs can both result from an
Global strategy for the prevention and control of AIDS [news]: World Health Forum. 1992;13(2-3):265-6. Unique Identifier : AIDSLINE MED/93039337
AIDS: a community commitment is the theme of World AIDS Day 1992 [news]: World Health Forum. 1992;13(2-3):270-1. Unique Identifier : AIDSLINE MED/93039338
Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation.: Immunol Today. 1992 Oct;13(10):405-11. Unique Identifier : AIDSLINE MED/93039356; Yodoi J; Uchiyama T; Dept of Biological Responses, Kyoto University, Japan.; HTLV-I, the etiological agent in adult T-cell leukemia, has also been strongly implicated in a number of non-neoplastic T-cell-associated diseases. Here, Junji Yodoi and Takashi Uchiyama review these associations and focus on the emerging concepts of IL-2R dysregulation and redox regulation by adult T-cell leukemia-de
Consensus statement from the consultation on HIV transmission and breastfeeding.: J Hum Lact. 1992 Sep;8(3):173-4. Unique Identifier : AIDSLINE MED/93039424
T helper cell immune dysfunction in asymptomatic, HIV-1-seropositive individuals: the role of TH1-TH2 cross-regulation.: Chem Immunol. 1992;54:21-43. Unique Identifier : AIDSLINE MED/93039657; Shearer GM; Clerici M; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, Md.
The HIV-1 nef gene product is associated with phosphorylation of a 46 kD cellular protein.: AIDS. 1992 Aug;6(8):787-91. Unique Identifier : AIDSLINE MED/93039860; Poulin L; Levy JA; Cancer Research Institute, University of California, School of; Medicine, San Francisco 94143.; OBJECTIVE: To study the biochemical properties of the HIV-1 nef gene product. DESIGN: Earlier reports suggested that Nef protein is phosphorylated and has kinase activity. These properties were examined using an in vitro translated product. METHODS: A DNA fragment encoding Nef of HIV-1SF2 was transcribed in vitro unde
Expression of activation antigens, HLA-DR and CD38, on CD8 lymphocytes during HIV-1 infection.: AIDS. 1992 Aug;6(8):793-7. Unique Identifier : AIDSLINE MED/93039861; Kestens L; Vanham G; Gigase P; Young G; Hannet I; Vanlangendonck F; Hulstaert F; Bach BA; Laboratory of Pathology and Immunology, Institute of Tropical; Medicine, Antwerp, Belgium.; OBJECTIVE: To study the expression of the activation markers human leukocyte antigen (HLA)-DR and CD38 antigen on CD8+ T-lymphocytes in HIV-infected subjects and HIV-negative controls. DESIGN: Two- and three-colour flow-cytometric analysis. METHODS: Fresh peripheral venous blood was obtained from 16 HIV-infected subje
Development of HIV-1 group-specific neutralizing antibodies after seroconversion.: AIDS. 1992 Aug;6(8):799-802. Unique Identifier : AIDSLINE MED/93039862; McKnight A; Clapham PR; Goudsmit J; Cheingsong-Popov R; Weber JN; Weiss RA; Chester Beatty Laboratories, Institute of Cancer Research,; London, UK.; OBJECTIVE: To study the induction of group-specific (gs) neutralizing antibodies to HIV-1 after seroconversion. DESIGN AND METHODS: Serum samples taken sequentially from seven Dutch homosexual men and four British haemophiliacs (anonymous sample, therefore sex not known) before and after seroconversion were tested for
Glutathione depletion in HIV-infected patients: role of cysteine deficiency and effect of oral N-acetylcysteine.: AIDS. 1992 Aug;6(8):815-9. Unique Identifier : AIDSLINE MED/93039865; de Quay B; Malinverni R; Lauterburg BH; Department of Clinical Pharmacology and Medizinische Poliklinik,; University of Bern, Switzerland.; OBJECTIVE: To determine whether a single oral dose of N-acetylcysteine corrects the deficiency of cysteine and glutathione in plasma and mononuclear cells of HIV-infected patients. DESIGN: Pharmacokinetic and pharmacodynamic study. METHODS: Cysteine and glutathione were measured in plasma and peripheral blood mononucl
The effect of treatment with zidovudine with or without acyclovir on HIV p24 antigenaemia in patients with AIDS or AIDS-related complex.: AIDS. 1992 Aug;6(8):821-5. Unique Identifier : AIDSLINE MED/93039866; Pedersen C; Cooper DA; Brun-Vezinet F; Doherty R; Skinhoj P; Perol Y; Luthy R; Leibowitch J; Habermehl KO; Varnier OE; et al; Hvidovre Hospital, Copenhagen, Denmark.; OBJECTIVE: To evaluate changes in serum HIV p24-antigen levels in a subset of patients who participated in a European/Australian double-blind, placebo-controlled trial evaluating the efficacy of zidovudine (250 mg every 6 h) alone or in combination with acyclovir (800 mg every 6 h) in patients with AIDS, AIDS-related
Pharmacokinetics of zidovudine in end-stage renal disease: influence of haemodialysis [see comments]: AIDS. 1992 Aug;6(8):827-30. Unique Identifier : AIDSLINE MED/93039867; Pachon J; Cisneros JM; Castillo JR; Garcia-Pesquera F; Canas E; Viciana P; Infectious Diseases Unit, Hospital Universitario Virgen del; Rocio, Sevilla, Spain.; OBJECTIVE: To study the pharmacokinetics of zidovudine (ZDV) and its glucoronide metabolite (G-ZDV) in a patient with end-stage renal disease in haemodialysis. DESIGN: Pharmacokinetics study performed during and between haemodialysis sessions. METHODS: The patient was treated with oral ZDV (100 mg every 8 h). Concentr
Pancreatitis and pancreatic dysfunction in patients taking dideoxyinosine.: AIDS. 1992 Aug;6(8):831-5. Unique Identifier : AIDSLINE MED/93039868; Seidlin M; Lambert JS; Dolin R; Valentine FT; Department of Medicine, New York University Medical Center, New; York.; OBJECTIVE: To describe the incidence, clinical characteristics and dose relationship of dideoxyinosine (ddI)-associated pancreatitis. DESIGN: Patients enrolled in a Phase I dose escalation trial of ddI [AIDS Clinical Trials Group (ACTG) 064] were evaluated for signs and symptoms of pancreatic dysfunction. SETTING: Two
Progressive multifocal leukoencephalopathy in HIV-1-infected children.: AIDS. 1992 Aug;6(8):837-41. Unique Identifier : AIDSLINE MED/93039869; Berger JR; Scott G; Albrecht J; Belman AL; Tornatore C; Major EO; Department of Neurology, University of Miami School of Medicine,; Florida 33136.; OBJECTIVE: To describe the clinical and pathologic features of two HIV-1-infected children with progressive multifocal leukoencephalopathy (PML). DESIGN: Case report. SETTING: University-affiliated, public-health trust hospital. METHODS: Two HIV-1-infected children with PML are described. A 13-year-old girl, presumed
The spectrum of HIV-1-related disease among outpatients in New York City.: AIDS. 1992 Aug;6(8):849-59. Unique Identifier : AIDSLINE MED/93039871; Greenberg AE; Thomas PA; Landesman SH; Mildvan D; Seidlin M; Friedland GH; Holzman R; Starrett B; Braun J; Bryan EL; et al; Office of AIDS Surveillance, New York City Department of Health,; New York 10013.; OBJECTIVES: To define the spectrum of HIV-1-related disease in New York City (NYC) and to determine how the clinical spectrum of illness differs in various populations. DESIGN AND METHODS: The medical records of the 2983 HIV-infected individuals who had received care through 1989 at four hospital outpatient clinics an
Maintenance of behavioral change in a cohort of homosexually active men [see comments]: AIDS. 1992 Aug;6(8):861-8. Unique Identifier : AIDSLINE MED/93039872; McCusker J; Stoddard AM; McDonald M; Zapka JG; Mayer KH; AIDS Research Unit, School of Public Health, University of; Massachusetts, Amherst 01003.; OBJECTIVES: To assess associations of perceptions of sexual behavior change with actual risk behaviors and psychosocial variables, and to determine whether perceptions of behavior change predict subsequent behavior. DESIGN: Cohort study of homosexually active men. SETTING: Community health center in Boston, Massachuse
HIV prevalence, attitudes and behaviour in clients of a confidential HIV testing and counselling centre in Uganda.: AIDS. 1992 Aug;6(8):869-74. Unique Identifier : AIDSLINE MED/93039873; Muller O; Barugahare L; Schwartlander B; Byaruhanga E; Kataaha P; Kyeyune D; Heckmann W; Ankrah M; AIDS Information Centre, Kampala, Uganda.; OBJECTIVE: To describe clients, operation and impact of an African public HIV testing and counselling centre. DESIGN AND SETTING: Analysis of samples from clients attending the AIDS Information Centre (AIC) in Kampala, Uganda in early 1991. SUBJECTS: HIV-1-positive and HIV-negative
Safer sex maintenance among gay men: are we making any progress? [editorial; comment]: AIDS. 1992 Aug;6(8):875-7. Unique Identifier : AIDSLINE MED/93039874; Ekstrand ML
AIDS-related secondary infections in patients with unknown HIV status [letter]: AIDS. 1992 Aug;6(8):879-80. Unique Identifier : AIDSLINE MED/93039875; Clezy K; Jones P
A case for the revision of the WHO clinical definition for African AIDS [letter]: AIDS. 1992 Aug;6(8):880-1. Unique Identifier : AIDSLINE MED/93039876; Belec L; Mbopi Keou FX; Georges AJ
HIV infection in Cameroon: 30 months' surveillance in Yaounde [letter]: AIDS. 1992 Aug;6(8):881-2. Unique Identifier : AIDSLINE MED/93039877; Garcia-Calleja JM; Zekeng L; Louis JP; Mvondo JL; Trebucq A; Sokal D; Yanga D; Ndoumou A; Andela D; Salla R; et al
Characteristics of newborns and HIV-1 infection in Rwanda [letter]: AIDS. 1992 Aug;6(8):882-3. Unique Identifier : AIDSLINE MED/93039878; Lepage P; Msellati P; Van de Perre P; Hitimana DG; Dabis F
HIV seroprevalence surveys in Uruguay [letter]: AIDS. 1992 Aug;6(8):884-5. Unique Identifier : AIDSLINE MED/93039879; Berriolo R; Colistro L; Rostkier J; Rivas B; Zessler L
Specific antitoxoplasmic immunoglobulin G detected by western blot in AIDS patients: relationship to visceral localization [letter]: AIDS. 1992 Aug;6(8):885-6. Unique Identifier : AIDSLINE MED/93039880; Pelloux H; Thelu J; Derouin F; Ambroise-Thomas P
Role of proteases as cofactors for antibody-dependent enhancement of HIV [letter]: AIDS. 1992 Aug;6(8):887-8. Unique Identifier : AIDSLINE MED/93039881; Zoellner B; Feucht HH; Laufs R
Antigenicity of the HIV-2 V3 loop [letter]: AIDS. 1992 Aug;6(8):888-9. Unique Identifier : AIDSLINE MED/93039882; Jones IM; Morikawa Y; Fenouillet E; Moore JP
Intramedullary tuberculoma in a patient with HIV infection [letter]: AIDS. 1992 Aug;6(8):889-91. Unique Identifier : AIDSLINE MED/93039883; Gallant JE; Mueller PS; McArthur JC; Chaisson RE
Pneumopathy and kidney abscess due to Nocardia farcinica in an HIV-infected patient [letter]: AIDS. 1992 Aug;6(8):891-3. Unique Identifier : AIDSLINE MED/93039884; Parmentier L; Salmon-Ceron D; Boiron P; Paul G; Guez T; Dupont B; Sicard D
A rapid and reliable method to create tandem arrays of short DNA sequences.: Biotechniques. 1992 Nov;13(5):780-9. Unique Identifier : AIDSLINE MED/93040203; Graham GJ; Maio JJ; Department of Cell Biology, Albert Einstein College of Medicine,; Bronx, NY 10461.; Tandemly polymerized regulatory elements, antisense RNA segments or ribozymes are potentially useful in selective gene silencing. However, existing methods of tandemly polymerizing short DNA segments are laborious. We present a procedure that can create cloned arrays of 40-70 monomer units in two steps. We have create
The human immunodeficiency virus: knowledge and precautions among anesthesiology personnel [letter]: J Clin Anesth. 1992 Jul-Aug;4(4):343. Unique Identifier : AIDSLINE MED/93040258; Maree SM
Problems of drug abuse, HIV and AIDS: the burden of care in one general practice [see comments]: Br J Gen Pract. 1992 Jun;42(359):232-5. Unique Identifier : AIDSLINE MED/93040553; Ronald PJ; Witcomb JC; Robertson JR; Roberts JJ; Shishodia PC; Whittaker A; Responsibility for many of the problems of intravenous drug abuse and human immunodeficiency virus (HIV) infection lies with community care agencies, such as general practitioners, community psychiatric and district nurses and drug agencies. It is in general practice that this burden is most clearly observed, given th
Treatment of poor prognosis Burkitt's lymphoma in adults with the Societe Francaise d'Oncologie Pediatrique LMB Protocol--a study of the Federation Nationale des Centres de Lutte Contre le Cancer (FNLCC).: Eur J Cancer. 1992;28A(12):1954-9. Unique Identifier : AIDSLINE MED/93040598; Philip T; Meckenstock R; Deconnick E; Carrie C; Bailly C; Colombat P; Dauriac C; Demaille MC; Salles B; Cahn JY; et al; 14 adult patients between 16 and 50 years old with small non-cleaved cell lymphoma (Burkitt s lymphoma) were prospectively treated from 1982 to 1990 with the LMB protocols of the Societe Francaise d Oncologie Pediatrique (SFOP). No HIV-positive patients were included. All patients had extensive disease with bad progno
'Transmission of HIV to dental patients: more data' [letter; comment]: Br Dent J. 1992 Oct 24;173(7):226. Unique Identifier : AIDSLINE MED/93040715; Lim M
[In the sunset of life. To be useful (interview by Siv Barstad)]: Sykepl Fag. 1992 Oct 12;80(5):21-3. Unique Identifier : AIDSLINE MED/93040750; Haugbo G
[Home and nursing home--filling a void (interview by Siv Barstad)]: J Sykepleien. 1992 Jun 1;80(10):12. Unique Identifier : AIDSLINE MED/93040764; Lyngas A
[Created in our image (interview by Siv Barstad)]: J Sykepleien. 1992 Jun 1;80(10):14-6. Unique Identifier : AIDSLINE MED/93040765; Biehl KH
The use of illustrations and narrative text style to improve readability of a health education brochure.: J Cancer Educ. 1992;7(3):251-60. Unique Identifier : AIDSLINE MED/93040983; Michielutte R; Bahnson J; Dignan MB; Schroeder EM; Department of Family and Community Medicine, Bowman Gray School; of Medicine, Wake Forest University, Winston-Salem, NC; 27157-1084.; Research suggests that much of the available health education literature requires a level of reading ability that makes it inaccessible to a large proportion of the population in greatest need of health information. The present study tested the value of illustrations and a narrative text style as means of improving th
The epidemiology of AIDS-associated non-Hodgkin's lymphoma in the World Health Organization European Region.: Br J Cancer. 1992 Nov;66(5):912-6. Unique Identifier : AIDSLINE MED/93041043; Serraino D; Salamina G; Franceschi S; Dubois D; La Vecchia C; Brunet JB; Ancelle-Park RA; Epidemiology Unit, Aviano Cancer Centre, Italy.; This paper describes the epidemiology of AIDS-associated non-Hodgkin s lymphoma (NHL) in the World Health Organization (WHO) European Region. Data, collected by the WHO Collaborating Centre on AIDS in Paris, France
Draft guidance on children affected or infected by HIV [news]: Nurs Stand. 1992 Sep 2-8;6(50):14. Unique Identifier : AIDSLINE MED/93041057
Health discrimination against gays [letter]: Nurs Stand. 1992 Sep 9-SEP 15;6(51):42. Unique Identifier : AIDSLINE MED/93041079; Dawkins A
Europe: a return to criminalisation.: Nurs Stand. 1992 Sep 16-22;6(52):22-3. Unique Identifier : AIDSLINE MED/93041088; Weaver K
Living will allows choice for people with HIV/AIDS [news]: Nurs Stand. 1992 Sep 16-22;6(52):5. Unique Identifier : AIDSLINE MED/93041098
AIDS focus. Educating for health.: Nurs Stand. 1992 Sep 16-22;6(52):50-2. Unique Identifier : AIDSLINE MED/93041099; Maxwell N
AIDS focus. Developing a vaccine for HIV.: Nurs Stand. 1992 Sep 16-22;6(52):53-5. Unique Identifier : AIDSLINE MED/93041100; Carr G; Hawkins P
AIDS focus. HIV roundup.: Nurs Stand. 1992 Sep 16-22;6(52):56. Unique Identifier : AIDSLINE MED/93041101; Weller B
'No' to blanket HIV pregnancy testing.: Nurs Stand. 1992 Sep 16-22;6(52):8. Unique Identifier : AIDSLINE MED/93041102
Patient autonomy: willing decisions [news]: Nurs Stand. 1992 Sep 23-29;7(1):17. Unique Identifier : AIDSLINE MED/93041110; O'Byrne J
A tremendous opportunity to influence services [news]: Nurs Stand. 1992 Sep 30-Oct 6;7(2):16. Unique Identifier : AIDSLINE MED/93041121
Occupational risk of HIV-associated TB [news]: Nurs Stand. 1992 Sep 30-Oct 6;7(2):17. Unique Identifier : AIDSLINE MED/93041122
Radical approach to HIV vaccine [news]: Nurs Stand. 1992 Sep 30-Oct 6;7(2):17. Unique Identifier : AIDSLINE MED/93041123
Measurements of blood flow and histometry of the cellular infiltrate in tuberculin skin test responses of the typical Koch type and the non-turgid variant form (Listeria-type) in pulmonary tuberculosis patients and apparently healthy controls.: Int J Exp Pathol. 1992 Oct;73(5):565-72. Unique Identifier : AIDSLINE MED/93041192; Potts RC; Beck JS; Gibbs JH; Grange JM; Kardjito T; Stanford JL; Department of Pathology, University of Dundee, Ninewells Hospital; and Medical School, UK.; The typical turgid Koch type and the non-turgid variant form (Listeria-type) of the tuberculin skin test responses were studied in 76 newly diagnosed pulmonary tuberculosis patients and 29 apparently healthy factory worker controls from Surabaya in Indonesia ; in general, the pat
Cellular and humoral immune responses in haemophiliacs after vaccination against tick-borne encephalitis.: Br J Haematol. 1992 Oct;82(2):374-83. Unique Identifier : AIDSLINE MED/93041250; Wolf HM; Pum M; Jager R; Istvan L; Mannhalter JW; Eibl MM; Institute of Immunology, University of Vienna, Austria.; The primary immune response to a viral antigen (tick-borne encephalitis, TBE) has been determined in haemophiliacs. Twelve HIV-negative and four clinically asymptomatic, HIV-positive haemophiliacs as well as 16 age-matched healthy controls were included in the study. Antibody responses after TBE vaccination were compa
Towards a new predictor of AIDS progression through the quantitation of HIV-1 DNA copies by PCR in HIV-infected individuals.: Br J Haematol. 1992 Oct;82(2):467-71. Unique Identifier : AIDSLINE MED/93041264; Lefrere JJ; Mariotti M; Wattel E; Lefrere F; Inchauspe G; Costagliola D; Prince A; Institut National de Transfusion Sanguine, Paris, France.; The proviral copy (PVC) number in peripheral blood mononuclear cells (PBMCs) of human immunodeficiency virus (HIV)-infected individuals was measured by a quantitative polymerase chain reaction (PCR) assay to determine over time the relation between the viral load and the evolution towards the disease in HIV-infected p
Spontaneous regression of Ki-1 positive T-cell non-Hodgkin's lymphoma in a patient with HIV infection [see comments]: Br J Haematol. 1992 Oct;82(2):477-8. Unique Identifier : AIDSLINE MED/93041269; Diekman MJ; Bresser P; Noorduyn LA; Reiss P; Department of Internal Medicine, Academic Medical Centre,; Amsterdam, The Netherlands.
Neuroradiology of intracranial infection.: Pediatr Neurosurg. 1992;18(2):92-104. Unique Identifier : AIDSLINE MED/93041283; Smith RR; Department of Radiology and Neurology, Indiana University School; of Medicine, Indianapolis.; The ability to detect and differentiate intracranial infection has markedly improved, first with the introduction of computed tomography and, more recently, with magnetic resonance. Enhanced magnetic resonance imaging is the procedure of choice in the evaluation of nearly all intracranial infections. The sensitivity o
Human T lymphotropic virus type-I (HTLV-I) immortalizes human T cells in vitro--its implication in the pathogenesis of adult T cell leukemia (ATL).: Hum Cell. 1992 Mar;5(1):70-8. Unique Identifier : AIDSLINE MED/93041473; Maeda M; Chest Disease Research Institute, Kyoto University.; HTLV-I is the first human retrovirus that was isolated from a patient with T-cell malignancy in 1980 in the United States . HTLV-I is detected in most patients with adult T cell leukemia (ATL) and healthy carriers, who are frequently found in the southwestern parts of Kyushu and Shikoku
Differences in HTLV-I integration patterns between skin lesions and peripheral blood lymphocytes of HTLV-I seropositive patients with cutaneous lymphoproliferative disorders.: J Dermatol Sci. 1992 Sep;4(2):76-82. Unique Identifier : AIDSLINE MED/93041514; Hamada T; Setoyama M; Katahira Y; Furuno T; Fujiyoshi T; Sonoda S; Tashiro M; Department of Dermatology, Faculty of Medicine, Kagoshima; University, Japan.; We examined HTLV-I integration patterns in nine cases of HTLV-I-seropositive patients with cutaneous lymphoproliferative disorders. The Southern blot on EcoRI digests of DNA revealed a discrete band of HTLV-I provirus (monoclonal integration) in either skin lesions or peripheral blood lymphocytes (PBL). Four cases sho
Comparative lectinhistochemical studies on paraffin- and glycol methacrylate-embedded CNS tissue specimens from AIDS autopsies. Mistletoe lectin I (ML I) as cell-marker.: Zentralbl Pathol. 1992 Sep;138(4):272-7. Unique Identifier : AIDSLINE MED/93041665; Artigas J; Bachler B; Habedank S; Taube F; Franz H; Niedobitek F; Institut fur Pathologie, Auguste-Viktoria-Krankenhaus; Berlin-Schoneberg, Deutschland.; Brain tissue and spinal cord tissue from 12 patients who had died of AIDS was fixed in neutral formalin; then after the embedment of some of it in paraffin and some of it in glycol methacrylate, it was analyzed lectinhistochemically with mistletoe lectin I (ML I). Mistletoe lectin (ML I) is a reliable marker for micro
Diversity in DNA rearrangements and in RNA expressions of immunoglobulin gene on common variable immunodeficiency.: Eur J Immunogen. 1992 Oct;19(5):273-85. Unique Identifier : AIDSLINE MED/93041676; Mori S; Kondo N; Motoyoshi F; Kaneko H; Inoue Y; Orii T; Department of Pediatrics, Gifu University School of Medicine,; Japan.; Six heterogeneous common variable immunodeficiency (CVID) patients were analysed for germ-line DNA, DNA rearrangements, and RNA expressions of immunoglobulin (Ig) gene by Southern or northern blotting using appropriate probes. We detected no polymorphism in neutrophil DNA hybridized to a C mu and a C gamma probe. In t
Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease.: Biochemistry. 1992 Oct 27;31(42):10153-68. Unique Identifier : AIDSLINE MED/93041701; Tomaszek TA Jr; Moore ML; Strickler JE; Sanchez RL; Dixon JS; Metcalf BW; Hassell A; Dreyer GB; Brooks I; Debouck C; et al; Department of Medicinal Chemistry, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania 19406.; The muscle and heart lactate dehydrogenase (LDHs) of rabbit and pig are specifically cleaved at a single position by HIV-1 protease, resulting in the conversion of 36-kDa subunits of the oligomeric enzymes into 21- and 15-kDa protein bands as analyzed by SDS-PAGE. While the proteolysis was observed at neutral pH, it b
Beliefs and behavioral intentions regarding human immunodeficiency virus testing among New York City runaways.: J Adolesc Health. 1992 Nov;13(7):576-81. Unique Identifier : AIDSLINE MED/93041803; Koopman C; Rotheram-Borus MJ; Dobbs L; Gwadz M; Brown J; Division of Child Psychiatry, Columbia University.; From 1988 to 1991, 139 runaways aged 11-19 years in the New York City area (n = 70 males, 69 females) were recruited from four shelters. Each runaway participated in a semistructured interview assessing beliefs and behavioral intentions regarding human immunodeficiency virus (HIV) testing. When asked how they would re
An evaluation of a school-based AIDS/HIV education program for high school students.: J Adolesc Health. 1992 Nov;13(7):582-8. Unique Identifier : AIDSLINE MED/93041804; Ashworth CS; DuRant RH; Newman C; Gaillard G; Department of Pediatrics, University of Alabama, Birmingham.; The effect of a 1-hr school-based AIDS/HIV education program on the knowledge and attitudes of high school students was evaluated with a modified version of the Centers for Disease Control Health Risk Survey. One urban and one suburban school each were randomly assigned to an educational intervention (n = 535) or a co
Synthesis, characterization and some properties of dideoxynucleoside analogs of cytidine diphosphate diacylglycerol.: Biochim Biophys Acta. 1992 Nov 11;1165(1):45-52. Unique Identifier : AIDSLINE MED/93041987; van Wijk GM; Hostetler KY; Suurmeijer CN; van den Bosch H; Center for Biomembranes and Lipid Enzymology, University of; Utrecht, Netherlands.; Phospholipid conjugates of antiretroviral nucleoside analogs have been proposed to have several advantageous features when compared to the parent drugs (Hostetler, K.Y. et al. (1990) J. Biol. Chem. 265, 6112-6117). Here we report on the synthesis of one such type of lipid conjugates, i.e., nucleosides diphosphate diac
A national survey of physicians' and nurses' attitudes toward endoscope cleaning and the potential for cross-infection.: Gastroenterol Nurs. 1992 Oct;15(2):59-65. Unique Identifier : AIDSLINE MED/93042042; Foss D; Monagan D; To elicit information on endoscope cleaning practices and the perceived risk of cross-infection, questionnaires were mailed to 500 physicians and 1,000 gastroenterology nurses and associates in November and December 1991. The survey results indicated that while the majority (83% of nurse/associates and 82% of physicia
Relationship between the immune system and frailty: pathogenesis of immune deficiency in HIV infection and aging.: Aging (Milano). 1992 Sep;4(3):255-7. Unique Identifier : AIDSLINE MED/93042082; Margolick JB; Chopra RK; Department of Environmental Health Sciences, Johns Hopkins; University, School of Public Health, Baltimore, MD 21205.
A novel method for the incorporation of glycoprotein-derived oligosaccharides into neoglycopeptides.: Bioconjug Chem. 1992 Sep-Oct;3(5):391-6. Unique Identifier : AIDSLINE MED/93042111; Wood SJ; Wetzel R; Macromolecular Sciences Department, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania 19406.; We describe a new method for the transfer of carbohydrate moieties to polypeptides in which complex carbohydrate, in the form of glycosyl amino acid, is removed from an available glycoprotein, derivatized, and reacted with a polypeptide via an iodoacetylated alpha-amino group. A family of oligomannose chains, N-linked
Activities of certain cytoplasmic enzymes in bovine T lymphoma.: J Vet Med Sci. 1992 Oct;54(5):1047-8. Unique Identifier : AIDSLINE MED/93042257; Arai T; Ageto H; Shinofuji T; Sugawara M; Division of Veterinary Biochemistry, Nippon Veterinary and Animal; Science University, Tokyo, Japan.; Activities of certain cytoplasmic enzymes were measured in bovine T lymphoma (BTL-PC3 cells). The activities of hexokinase, pyruvate kinase and glucose-6-phosphate dehydrogenase in PC3 cells were elevated as much as 2 or 3-fold of those in bovine thymocyte. The high activities of these enzymes derived from activation
The immunomodulatory role of IFN-alpha or maltose-stabilized IFN-alpha on T-cell activation.: Lymphokine Cytokine Res. 1992 Aug;11(4):221-7. Unique Identifier : AIDSLINE MED/93042308; Kohno K; Holan V; Matsuda S; Kurimoto M; Minowada J; Fujisaki Cell Center, Hayashibara Biochemical Laboratories, Inc.,; Okayama, Japan.; The effects of human interferon-alpha (IFN-alpha) or maltose-stabilized IFN-alpha (MS-IFN-alpha) on IL-2 production by PHA- or anti-CD3 mAb-stimulated MOLT 16 cells, a human leukemic T cell line, were studied. MS-IFN-alpha is an IFN-alpha-containing powder in which mal
Comparison of mycobacterial lymphadenitis among persons infected with human immunodeficiency virus and seronegative controls.: Clin Infect Dis. 1992 Oct;15(4):601-5. Unique Identifier : AIDSLINE MED/93042409; Shriner KA; Mathisen GE; Goetz MB; Department of Medicine, UCLA/San Fernando Valley Program.; Lymphadenitis is a common extrapulmonary manifestation of mycobacterial disease in persons with human immunodeficiency virus (HIV) infection. We compared the clinical, mycobacterial, and diagnostic characteristics of mycobacterial adenitis in 11 HIV-seropositive and 29 HIV-seronegative patients. Ninety-three percent o
Pyomyositis in North America: case reports and review.: Clin Infect Dis. 1992 Oct;15(4):668-77. Unique Identifier : AIDSLINE MED/93042419; Christin L; Sarosi GA; Department of Internal Medicine, Maricopa Medical Center,; Phoenix, Arizona 85010-5099.; We report two cases and review the characteristics of pyomyositis. The courses of patients who presented with pyomyositis at the Maricopa Medical Center (Phoenix) are detailed. Ninety-eight reported cases over the last 20 years in North America, found through a MEDLINE search, are summarized. Infection with the human
Maternal-fetal transmission of human immunodeficiency virus: a review of possible routes and cellular mechanisms of infection [see comments]: Clin Infect Dis. 1992 Oct;15(4):678-91. Unique Identifier : AIDSLINE MED/93042420; Douglas GC; King BF; Department of Cell Biology and Human Anatomy, School of Medicine,; University of California, Davis 95616-8643.; The prevalence of human immunodeficiency virus (HIV) infections among children is increasing in a manner that closely follows the spread of the disease among women. Despite the fact that in utero transmission via the placenta is though to play a major role in the spread of HIV to the pediatric population, little is kn
Tuberculosis of the breast as a presenting manifestation of AIDS.: Clin Infect Dis. 1992 Oct;15(4):692-3. Unique Identifier : AIDSLINE MED/93042421; Hartstein M; Leaf HL; Department of Medicine, New York University School of Medicine,; New York.; Tuberculous infections of the breast are considered rare in the developed world. We describe a case of mammary tuberculosis in a woman who was not initially known to be seropositive for the human immunodeficiency virus (HIV) and who was thought to have a pyogenic breast abscess. This uncommon presentation of extrapulm
Meningitis due to Prototheca wickerhamii in a patient with AIDS.: Clin Infect Dis. 1992 Oct;15(4):704-6. Unique Identifier : AIDSLINE MED/93042425; Kaminski ZC; Kapila R; Sharer LR; Kloser P; Kaufman L; Department of Laboratory Medicine, UMDNJ-New Jersey Medical; School, University Hospital, Newark 07103-2425.; The first documented case of algal meningitis due to Prototheca wickerhamii is reported in a patient with AIDS. The initial CSF culture yielded only Cryptococcus neoformans. P. wickerhamii was isolated on four subsequent lumbar punctures. The patient died, and at autopsy the alga was isolated from leptomeninges over t
An unusual case of false-positive serology for the human immunodeficiency virus: report from the heterosexual HIV transmission study.: Clin Infect Dis. 1992 Oct;15(4):707-9. Unique Identifier : AIDSLINE MED/93042426; Louria DB; Denny T; Palumbo P; Rios M; Bianco C; Department of Preventive Medicine and Community Health,; University of Medicine and Dentistry of New Jersey, New Jersey; Medical School, Newark 07103-2757.; A man was found to have a repeatedly positive enzyme immunoassay (EIA) that was confirmed by a western blot with six positive bands. He was told that he was seropositive for the human immunodeficiency virus (HIV), but subsequent EIAs were negative and western blots were either negative or indeterminant. All other HIV-
AIDS enteropathy [see comments]: Clin Infect Dis. 1992 Oct;15(4):726-35. Unique Identifier : AIDSLINE MED/93042432; Bartlett JG; Belitsos PC; Sears CL; Department of Medicine, Johns Hopkins University School of; Medicine, Baltimore, Maryland 21205.; Chronic diarrhea is one of the hallmarks of advanced human immunodeficiency virus (HIV) disease. The symptoms of this complication are troublesome, have a significant impact on the patient s quality of life, and in severe cases can lead to extreme abnormalities in fluids and electrolytes and can even cause death. The
Immunity to measles and rubella in women infected with human immunodeficiency virus [letter]: Clin Infect Dis. 1992 Oct;15(4):739. Unique Identifier : AIDSLINE MED/93042435; Clark RA; Dlamini G; Brandon W; Wisniewski T
Sporothrix schenckii meningitis in a patient with AIDS [letter]: Clin Infect Dis. 1992 Oct;15(4):741-3. Unique Identifier : AIDSLINE MED/93042438; Penn CC; Goldstein E; Bartholomew WR
Good response to antibiotic treatment of lung infection due to Rhodococcus equi in a patient infected with human immunodeficiency virus [letter]: Clin Infect Dis. 1992 Oct;15(4):747-8. Unique Identifier : AIDSLINE MED/93042443; Sasal M; Roig J; Cervantes M; Matas L; Segura F
Life-threatening Pseudomonas aeruginosa infections in patients with infection due to human immunodeficiency virus [letter]: Clin Infect Dis. 1992 Oct;15(4):751-2. Unique Identifier : AIDSLINE MED/93042447; Lozano F; Corzo JE; Nogales C; Garcia-Bragado F
[Infectious endocarditis in parenteral drug addicts: study of 57 cases]: An Med Interna. 1992 Oct;9(10):473-7. Unique Identifier : AIDSLINE MED/93042508; Gabriel Botella F; Labios Gomez M; Balaguer Martinez JV; Vera Sempere G; Tormo Diaz M; Roda Ribera J; Servicio de Medicina Interna, Hospital Clinico Universitario,; Valencia.; We present 57 cases of infectious endocarditis (IE) in 51 parenterally drug addicts (PDA) admitted at the Internal Medicine Service of the Hospital Clinico of Valencia between January ist, 1988 and January 15th, 1992. The disease affected young patients, 84% of them being HIV-1+ and 86% presenting CD4+ lymphocytes low
[Clinical syndromes in HIV infection (part 2)]: An Med Interna. 1992 Oct;9(10):501-8. Unique Identifier : AIDSLINE MED/93042516; Soriano V; Gonzalez-Lahoz J; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos; III, Madrid.; The spectrum of clinical manifestations associated to HIV infection is very broad. In addition to processes that may be attributed to the virus itself, multiple opportunistic infections can develop while the immunodeficiency develops. Any organ or system of the organism may be affected by these processes. The main cli
A parametric family of correlation structures for the analysis of longitudinal data.: Biometrics. 1992 Sep;48(3):733-42. Unique Identifier : AIDSLINE MED/93042617; Munoz A; Carey V; Schouten JP; Segal M; Rosner B; Department of Epidemiology, Johns Hopkins School of Public; Health, Baltimore, Maryland 21205.; In epidemiological settings, we are often faced with numerous short time series, and a parsimonious parametrization of the correlation structure is desired in order to optimize the efficiency of the estimation procedure. We propose a damped exponential correlation structure for modeling multivariate Gaussian outcomes.
Is the AIDS virus responsible for the disease? [editorial]: Biomed Pharmacother. 1992;46(1):1-2. Unique Identifier : AIDSLINE MED/93042856; Mathe G
Retrospective study correlating clinical infectious history and peripheral blood T-cell subpopulations in cancer, GvH and HIV+ patients.: Biomed Pharmacother. 1992;46(1):17-9. Unique Identifier : AIDSLINE MED/93042857; Mathe G; Meyer P; Brienza S; Gil-Delgado M; Orbach-Arbouys S; Itzhaki M; Institut du Cancer et d'Immunogenetique (CNRS and Association; Claude Bernard), Villejuif, France.; The CD4+ CD8- inducer helper cell and the CD4- CD8+ cytotoxic/suppressor cell absolute numbers were measured in the peripheral blood of patients with various pathological conditions: with leukemia-lymphomas or solid tumors, patients with bone marrow grafts suffering from GvH, HIV-1 asymptomatic carriers, ARC and AIDS
Analysis of purine nucleotides in lymphocytes from healthy subjects and AIDS patients.: Biomed Pharmacother. 1992;46(1):25-9. Unique Identifier : AIDSLINE MED/93042859; Tabucchi A; Carlucci F; Ramazzotti E; Re MC; Marinello F; Rubino M; Pagani R; Istituto di Biochimica e di Enzimologia, Universita di Siena,; Italy.; The most important purine nucleotides (NAD, AMP, IMP, GMP, XMP, ADP, ATP, GDP, GTP) were analyzed by HPLC in the lymphocytes of healthy subjects and HIV-1 seropositive patients at different stages of the disease (ARC-AIDS). Several differences, which focus attention on the behaviour of purine nucleotide metabolism in
The role of drugs in the origin of AIDS.: Biomed Pharmacother. 1992;46(1):3-15. Unique Identifier : AIDSLINE MED/93042860; Duesberg PH; Department of Molecular and Cell Biology, University of; California, Berkeley 94720.; It is proposed that the new American and European AIDS epidemics are caused by recreational and anti-HIV drugs rather than by human immunodeficiency virus (HIV). Chronologically, the AIDS epidemic in the 1980s followed a massive escalation in the consumption of recreational drugs that started in the 1960s and 70s. Epi
Immunogenicity of combined anti-HIV and anti-suppressive vaccine preparations.: Biomed Pharmacother. 1992;46(4):149-53. Unique Identifier : AIDSLINE MED/93042876; Carelli C; Halbreich A; Bernard J; Bizzini B; Achour A; Zagury JF; Lebon P; Polliotti B; Folghera S; Laaroubi K; et al; INSERM U36, Paris, France.; HIV-1 antigens generate in man both a humoral and cellular immune reaction. However, in ARC/AIDS patients, the cellular response is inhibited by HIV-1 which induces an antiproliferative (suppressive) effect on activated T cells. To overcome this inhibition and up-regulate the cellular response, we designed a new vacci
Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120.: Neuroreport. 1992 Oct;3(10):913-5. Unique Identifier : AIDSLINE MED/93042966; Lipton SA; Laboratory of Cellular and Molecular Neuroscience,; Harvard-Longwood Neurology Program, Boston, MA 02115.; HIV-1-related neuronal injury may involve a complex web of viral proteins and cytokines, but neurons themselves are not infected. The HIV envelope protein gp120 has been shown to engender an early increase in neuronal free calcium followed by delayed excitotoxic-like damage, which is prevented by N-methyl-D-aspartate
Altered expression of protein kinase C in adult T-cell leukemia cells.: Int J Hematol. 1992 Oct;56(2):135-41. Unique Identifier : AIDSLINE MED/93043067; Hidaka M; Nakakuma H; Kawaguchi T; Nagakura S; Horikawa K; Okuno Y; Kagimoto T; Takatsuki K; Second Department of Internal Medicine, Kumamoto University; Medical School, Japan.; Protein kinase C (PKC) has been shown to be involved in the mitogenic response and in oncogenic cell transformation in many experimental models. We analyzed the expression of PKC in both highly purified leukemic T cells freshly isolated from adult T-cell leukemia (ATL) patients and control T lymphocytes obtained from
[MR tomographic volumetry of the subarachnoid space in HIV-associated brain atrophy]: Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1992 Nov;157(5):466-70. Unique Identifier : AIDSLINE MED/93043088; Handwerker M; Krahe T; Klinker H; Schindler R; Institut fur Rontgendiagnostik, Universitat Wurzburg.; The CSF volume of 45 patients with HIV infection was measured at various clinical stages and the results compared with 24 normals. 60% of all patients showed increased CSF spaces as an indication of cerebral atrophy. Serial measurements were particularly valuable during the early stages of atrophy since there is marke
Changes in T-helper cell function in human immunodeficiency virus-infected children during didanosine therapy as a measure of antiretroviral activity.: Blood. 1992 Nov 1;80(9):2196-202. Unique Identifier : AIDSLINE MED/93043331; Clerici M; Roilides E; Butler KM; DePalma L; Venzon D; Shearer GM; Pizzo PA; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892.; Didanosine has shown activity against the human immunodeficiency virus (HIV) in both children and adults. We prospectively assessed T-helper cell (Th) function as determined by in vitro interleukin-2 ( IL-2 ) production in response to a panel of T-cell stimuli in 22 HIV-
Silent human immunodeficiency virus type 1 infection: a rare occurrence in a high-risk heterosexual population.: Blood. 1992 Nov 1;80(9):2396-400. Unique Identifier : AIDSLINE MED/93043357; Brettler DB; Somasundaran M; Forsberg AF; Krause E; Sullivan JL; Department of Medicine, University of Massachusetts Medical; School, Worcester.; A group of 58 heterosexual female partners (FP) of human immunodeficiency virus type 1 (HIV-1)-seropositive hemophiliacs was studied by conventional diagnostic methods such as enzyme-linked immunosorbent assay (ELISA) and Western blot analysis to examine whether any had acquired HIV-1 infection through sexual transmis
The occupational hazards of jury duty.: Bull Am Acad Psychiatry Law. 1992;20(3):325-33. Unique Identifier : AIDSLINE MED/93043584; Kaplan SM; Winget C; Department of Psychiatry, University of Cincinnati College of; Medicine, OH 45267-0559.; Jurors on criminal trials carry a considerable burden of responsibility. They determine the defendant s fate. Additionally, during trials they can be exposed to stressful, frightening, and sordid aspects of life. The stressfulness varies depending upon the nature of the trial, its length, the nature of the testimony a
Epidemiology of tuberculosis in Rhode Island.: R I Med. 1992 Sep;75(9):437-8. Unique Identifier : AIDSLINE MED/93043624; Romulo R; Brown University School of Medicine and Tuberculosis Clinic.; The increase in the reported cases of tuberculosis in Rhode Island from 1985 to 1991 has been striking. This rise has occurred at a faster rate than that for the United States overall. Although the HIV epidemic is largely to blame for the resurgence of tuberculosis nationwide, its impa
Hypersensitivity and anaphylactoid reactions to ciprofloxacin.: Ann Pharmacother. 1992 Sep;26(9):1081-4. Unique Identifier : AIDSLINE MED/93043717; Deamer RL; Prichard JG; Loman GJ; Ventura County Medical Center, Office of Medical Education, CA; 93003.; OBJECTIVE: To report three cases of life-threatening hypersensitivity reactions to the oral administration of ciprofloxacin. CASE SUMMARY: Life-threatening hypersensitivity reactions to oral ciprofloxacin, characterized by diffuse, erythematous, nonpruritic, blanching rash, with fever and hypotension, occurred in two
Clarithromycin: review of a new macrolide antibiotic with improved microbiologic spectrum and favorable pharmacokinetic and adverse effect profiles.: Ann Pharmacother. 1992 Sep;26(9):1099-108. Unique Identifier : AIDSLINE MED/93043726; Sturgill MG; Rapp RP; Department of Pharmacy Practice and Administration, Rutgers; College of Pharmacy, Piscataway, NJ 08855.; OBJECTIVE: To compare the new macrolide antibiotic clarithromycin with erythromycin in terms of in vitro activity, pharmacokinetics, pharmacodynamics, clinical efficacy, and toxicity. DATA IDENTIFICATION: An English-language literature search employing MEDLINE (1987-91), Index Medicus (1987-91), Program and Abstracts
Adjuvant corticosteroid therapy for Pneumocystis carinii pneumonia in AIDS patients.: Ann Pharmacother. 1992 Sep;26(9):1127-33. Unique Identifier : AIDSLINE MED/93043729; Sistek CJ; Wordell CJ; Hauptman SP; Department of Pharmacy, Thomas Jefferson University Hospital,; Philadelphia, PA 19107.; OBJECTIVE: To review published abstracts, case reports, and journal articles and evaluate data examining the use of systemic corticosteroids as adjuvant treatment for Pneumocystis carinii pneumonia (PCP) in patients with AIDS. DATA SOURCES: Computerized online databases, peer-reviewed journals from January 1986 throug
Immunological studies on opportunistic infection and the development of adult T-cell leukemia.: Intern Med. 1992 Sep;31(9):1132-6. Unique Identifier : AIDSLINE MED/93043801; Tashiro T; Yamasaki T; Nagai H; Kikuchi H; Nasu M; Second Department of Internal Medicine, Oita Medical University,; Japan.; Three patients with opportunistic infection preceding adult T-cell leukemia (ATL) are presented: a 66-year-old woman with cryptococcosis and Pneumocystis carinii pneumonia, a 46-year-old man with Pneumocystis carinii pneumonia, and a 55-year-old woman with cryptococcosis. Although, at the first examination, the first
Synthetic vaccines and HIV-1 hypervariability: a mixotope approach.: Pept Res. 1992 Jul-Aug;5(4):211-6. Unique Identifier : AIDSLINE MED/93043902; Gras-Masse H; Ameisen JC; Boutillon C; Rouaix F; Bossus M; Deprez B; Neyrinck JL; Capron A; Tartar A; Universite Lille II, URA CNRS 1309, Institut Pasteur, France.; The hypervariability of the gp120 envelope protein principal neutralizing domain, the V3 loop, represents a major problem in the design of vaccines against HIV-1. We have designed a mixed V3 loop peptide, termed mixotope, obtained in a unique synthesis, and containing around 7.5 x 10(5) different sequences of 22 to 25
Primary and secondary ethical issues arising from the introduction of recombinant factor VIII: primum non nocere, but what next?: Transfus Med Rev. 1992 Oct;6(4):271-6. Unique Identifier : AIDSLINE MED/93043925; McDonald M; Centre for Applied Ethics, University of British Columbia,; Vancouver, Canada.
Psychosocial issues surrounding the general or restricted use of recombinant factor VIII: hemophilia clinic perspective.: Transfus Med Rev. 1992 Oct;6(4):277-9. Unique Identifier : AIDSLINE MED/93043926; McDonald JR; Faculty of Social Work, Rehabilitation Studies, University of; Calgary, Canada.
The past and the future: recombinant factor VIII and the consumer.: Transfus Med Rev. 1992 Oct;6(4):280-3. Unique Identifier : AIDSLINE MED/93043927; Isaac BM; Hemophilia Canadian Society, Calgary, Alberta, Canada.
Persistent diarrhea associated with AIDS.: Acta Paediatr Suppl. 1992 Sep;381:45-8. Unique Identifier : AIDSLINE MED/93044053; Keusch GT; Thea DM; Kamenga M; Kakanda K; Mbala M; Brown C; Davachi F; ICAR Unit, Mama Yemo Hospital, Kinshasa, Zaire.; Chronic diarrhea and wasting are very common manifestations of AIDS in adults in developing countries. Etiologic studies show that protozoa (including Cryptosporidium parvum, Isospora belli, and Enterocytozoon bieniusi) and Mycobacterium avium-intracellulara are the most frequently identified pathogens. Limited data i
Limits to the criminal law in healthcare [editorial]: Br J Nurs. 1992 Sep 24-Oct 7;1(10):483. Unique Identifier : AIDSLINE MED/93044117; Dimond B
Oligodeoxyribonucleotide phosphorothioate fluxes and localization in hematopoietic cells.: Antisense Res Dev. 1992 Spring;2(1):27-39. Unique Identifier : AIDSLINE MED/93044239; Marti G; Egan W; Noguchi P; Zon G; Matsukura M; Broder S; Division of Biochemistry and Biophysics, Food and Drug; Administration, Bethesda, Maryland.; An antisense oligonucleotide phosphorothioate, previously shown to inhibit HIV-1 viral expression in chronically infected H9 cells, was fluorescently labeled to study oligonucleotide fluxes and localization within living cells. Observations based on flow cytometry and fluorescence microscopy show the following: within
Increased gut parasympathetic activity and chronic diarrhoea in a patient with the acquired immunodeficiency syndrome.: Clin Auton Res. 1992 Oct;2(5):295-8. Unique Identifier : AIDSLINE MED/93044255; Coker RJ; Horner P; Bleasdale-Barr K; Harris JR; Mathias CJ; Department of Genitourinary Medicine, St Mary's Hospital, London.; A 25-year-old homosexual man with a 2-year history of watery diarrhoea and a 20 kg weight loss is described. He had been diagnosed HIV-1 antibody positive 6 years previously. Investigations excluded opportunist pathogens and other known causes of diarrhoea. A range of anti-diarrhoeal medication had been unsuccessful.
Temazepam misuse in a group of injecting drug users.: Br J Addict. 1992 Oct;87(10):1387-92. Unique Identifier : AIDSLINE MED/93044266; Ruben SM; Morrison CL; Liverpool Drug Dependency Clinic, UK.; It is well recognized that many injecting drug users are poly-drug users. The intravenous use of Temazepam has become popular recently. In response to the ease of misuse, the pharmaceutical industry produced a formulation that would be as resistant as possible to injecting. The preparation is a gel-filled formulatio
Purification of an active monomeric recombinant HIV-1 trans-activator.: Protein Expr Purif. 1992 Apr;3(2):126-33. Unique Identifier : AIDSLINE MED/93044540; Waszak GA; Hasler JM; McQuade TJ; Tarpley WG; Deibel MR Jr; Upjohn Laboratories, Upjohn Company, Kalamazoo, Michigan 49001.; A method for the purification of a truncated, biologically active human immunodeficiency virus type 1 (HIV-1) trans-activator (rTAT) from recombinant Escherichia coli is reported here. The purification steps utilized include mild extraction (French press), concentration by ammonium sulfate precipitation, chromatograph
Variations in thyroid hormone transport proteins and their clinical implications.: Thyroid. 1992 Fall;2(3):237-45. Unique Identifier : AIDSLINE MED/93044582; Bartalena L; Robbins J; Genetics and Biochemistry Branch, NIDDK, NIH, Bethesda, Maryland.; Variations in major thyroid hormone transport proteins may be inherited or acquired and may be associated with changes in serum concentration of the proteins or their affinity for thyroid hormones. These variations most frequently involve thyroxine-binding globulin (TBG), but changes in transthyretin and albumin are a
AIDS: essentials of AZT for nurses.: Concern. 1992 Oct;21(5):28. Unique Identifier : AIDSLINE MED/93044599; Clausson N; Norton D
[Quantitative and qualitative anomalies of sperm in African individuals infected with HIV]: Bull Soc Pathol Exot. 1992;85(3):205-7. Unique Identifier : AIDSLINE MED/93044643; Gresenguet G; Belec L; Herve VM; Massanga M; Martin PM; Service National des Maladies Sexuellement Transmissibles,; Bangui, Republique centrafricaine.; Semen from 16 HIV1-infected african individuals (12 at stage II/CDC; 4 with pre-AIDS) has been analyzed both quantitatively (volume; number of spermatozoa) and qualitatively (motility). 12 healthy HIV1-seronegative individuals were recruited as controls. The HIV1-infected patients showed generally abnormalities of the
The practical management of haemophilia.: Blood Rev. 1992 Sep;6(3):174-81. Unique Identifier : AIDSLINE MED/93044740; Winter M; East Kent Haemophilia Centre, Thanet District Hospital, Margate,; Kent, UK.; Haemophilia is a rare and complex disorder and its successful management will depend upon the establishment of a network of comprehensive care including the services of haematologists, orthopaedic surgeons, rheumatologists, dental surgeons, physiotherapists, specialised nurses and counsellors. One of the major lesso
Heterosexual AIDs epidemic [letter]: BMJ. 1992 Sep 26;305(6856):772. Unique Identifier : AIDSLINE MED/93044835; Ford C
Breast feeding and HIV infection [editorial] [see comments]: BMJ. 1992 Oct 3;305(6857):788-9. Unique Identifier : AIDSLINE MED/93044846; Cutting WA
Female streetworking prostitution and HIV infection in Glasgow.: BMJ. 1992 Oct 3;305(6857):801-4. Unique Identifier : AIDSLINE MED/93044851; McKeganey N; Barnard M; Leyland A; Coote I; Follet E; Public Health Research Unit, University of Glasgow.; OBJECTIVES--To identify the extent of HIV infection and injecting drug use among female streetworking prostitutes in Glasgow; to estimate the size of the female streetworking prostitute population in the city; and to estimate the number of HIV positive women working as prostitutes on the streets in Glasgow. DESIGN--Ob
False positive salivary HIV test [letter] [see comments]: BMJ. 1992 Oct 3;305(6857):834. Unique Identifier : AIDSLINE MED/93044884; Morris DF
AIDS: guidelines for barbers [letter]: BMJ. 1992 Oct 3;305(6857):835. Unique Identifier : AIDSLINE MED/93044885; Bignardi G
Magic leaves Bush's AIDS commission [news]: BMJ. 1992 Oct 10;305(6858):852. Unique Identifier : AIDSLINE MED/93044895; Tanne JH
Hodgkin's disease involving the gingiva in AIDS.: Eur J Cancer B Oral Oncol. 1992 Jul;28B(1):39-41. Unique Identifier : AIDSLINE MED/93044980; Laskaris G; Stergiou G; Kittas C; Scully C; Andreas Sygros Hospital, University of Athens.; Non-Hodgkin lymphomas are a recognised complication of AIDS and may involve the oral cavity. However, no case of Hodgkin s disease affecting the oral cavity in AIDS appears to have been recorded. We report a male homosexual with AIDS and Hodgkin s lymphoma, who presented with gingival involvement.
Pneumocystis carinii pneumonitis following bone marrow transplantation.: Bone Marrow Transplant. 1992 Sep;10(3):267-72. Unique Identifier : AIDSLINE MED/93045009; Tuan IZ; Dennison D; Weisdorf DJ; Department of Medicine, University of Minnesota, Minneapolis.; Pneumocystis carinii pneumonitis (PCP) can occur in immunocompromised hosts, especially AIDS and cancer patients. Although recent research has focused on PCP in AIDS patients, few studies have described the clinical presentation of PCP in recipients of bone marrow transplantation (BMT). Between 1976 and 1991, of 1454
A decade of AIDS literature.: Bull Med Libr Assoc. 1992 Oct;80(4):380-1. Unique Identifier : AIDSLINE MED/93045047; Pratt GF; Houston Academy of Medicine-Texas Medical Center Library 77030.; From 1983 through mid-1991, more than 200,000 MEDLINE entries were AIDS-related. Close to 60% of the journals indexed in MEDLINE published at least one article on AIDS during the past ten years. As reflected by a subset of 29,077 MEDLINE records, the literature of AIDS has grown to encompass 29 languages and 65 countr
Intrathoracic lymphadenopathy and HIV infection.: Br J Radiol. 1992 Oct;65(778):940-2. Unique Identifier : AIDSLINE MED/93045300; Cowan NC; Salisbury JR; Moxham J; Department of Radiology, King's College Hospital, London, UK.
Attitudes of cardiothoracic surgeons in the UK to human immunodeficiency virus [letter; comment]: Br J Surg. 1992 Oct;79(10):1111. Unique Identifier : AIDSLINE MED/93045379; Underwood MJ; Weeresena N; Graham TR; Bailey JS; Firmin RK
Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease.: Brain. 1992 Oct;115 ( Pt 5):1249-73. Unique Identifier : AIDSLINE MED/93045438; Heyes MP; Saito K; Crowley JS; Davis LE; Demitrack MA; Der M; Dilling LA; Elia J; Kruesi MJ; Lackner A; et al; Section on Analytical Biochemistry, NIMH, NIH, Bethesda, MD; 20892.; Neurological dysfunction, seizures and brain atrophy occur in a broad spectrum of acute and chronic neurological diseases. In certain instances, over-stimulation of N-methyl-D-aspartate receptors has been implicated. Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate receptor agonist synthesized from L-trypt
Absence of HTLV-I and HTLV-II proviral genome in the brains of patients with multiple sclerosis and amyotrophic lateral sclerosis.: Can J Neurol Sci. 1992 Nov;19(4):458-61. Unique Identifier : AIDSLINE MED/93045831; Dekaban GA; Hudson AJ; Rice GP; Department of Clinical Neurological Sciences, University of; Western Ontario, London, Canada.; Previous studies have failed to provide serological evidence to incriminate a retroviral infection in the cause of multiple sclerosis. Gene amplification techniques have also failed to identify retroviral footprints in DNA from peripheral blood leukocytes. Here we provide evidence that proviral DNA of HTLV-I and HTLV-
Prevalence of antibody to human T-cell lymphotropic virus type I/II in people of Caribbean origin in Toronto.: Can Med Assoc J. 1992 Nov 15;147(10):1493-8. Unique Identifier : AIDSLINE MED/93045900; Chiavetta J; Nusbacher J; Tam F; Wall A; Steaffens J; Lee H; Blood Transfusion Service, Canadian Red Cross Society, Toronto; Centre, Ont.; OBJECTIVE: To estimate the prevalence of antibody to human T-cell lymphotropic virus type I/II (anti-HTLV-I/II) in people from an HTLV-I/II-endemic area (the Caribbean) living in a nonendemic region ( Canada ). DESIGN: Cross-sectional household survey. SETTING: Households in Toronto
Tuberculosis.: Clin Geriatr Med. 1992 Nov;8(4):761-75. Unique Identifier : AIDSLINE MED/93045962; Dutt AK; Stead WW; Alvin C. York Department of Veterans Affairs Medical Center,; Murfreesboro.; In the United States , the incidence of tuberculosis (TB) is higher in elderly persons than in any other segment of the population, except in HIV-infected persons. The diagnosis of TB, however, is all too often not considered in geriatric patients. Although elderly nursing home resident
Chagas' disease.: Clin Microbiol Rev. 1992 Oct;5(4):400-19. Unique Identifier : AIDSLINE MED/93046066; Tanowitz HB; Kirchhoff LV; Simon D; Morris SA; Weiss LM; Wittner M; Department of Pathology, Albert Einstein College of Medicine,; Bronx, New York.; Chagas disease, caused by Trypanosoma cruzi, is an important cause of morbidity in many countries in Latin America. The important modes of transmission are by the bite of the reduviid bug and blood transfusion. The organism exists in three morphological forms: trypomastigotes, amastigotes, and epimastigotes. The mech
T-cell subset analysis of Lewis lung carcinoma tumor rejection: heterogeneity of effectors and evidence for negative regulatory lymphocytes correlating with metastasis.: Cancer Res. 1992 Dec 1;52(23):6507-15. Unique Identifier : AIDSLINE MED/93046169; Gelber C; Eisenbach L; Feldman M; Goodenow RS; Division of Immunology and Rheumatology, Stanford University; School of Medicine, California 94305.; We have analyzed the phenotypes of the T-cell subsets generated in response to Lewis lung carcinoma clones in C57BL/6J recipients. The metastatic derivative, which expresses low levels of H-2Kb gene, predominantly elicited CD8, V beta 8, and V beta 9+ T-cells. The nonmetastatic clone expressing high levels of H-Kb gen
T cell immune response to cancer in humans and its relevance for immunodiagnosis and therapy.: Cancer Surv. 1992;13:173-204. Unique Identifier : AIDSLINE MED/93046227; Oliver RT; Nouri AM; Department of Medical Oncology, Royal London Hospital Medical; College.; Review of the relationship between the degree of immunosuppression and malignancy in patients on immunosuppressive drugs or immunosuppressed by HIV infection, postoperative blood transfusion or pregnancy provides the most convincing evidence of the importance of intact T cell immunity in resistance to cancer. Defectiv
Clinical, immunopathologic, and therapeutic considerations of inflammatory myopathies.: Clin Neuropharmacol. 1992 Oct;15(5):327-51. Unique Identifier : AIDSLINE MED/93046248; Dalakas MC; Neuromuscular Diseases Section, NINDS, National Institutes of; Health, Bethesda, MD 20892.; The inflammatory myopathies encompass a group of heterogenous muscle diseases which have in common an acquired myopathy with histological signs of endomysial inflammation. We present evidence based on recently emerged clinical, histologic, immunopathologic, demographic and therapeutic observations that these myopathie
Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth.: Chem Biol Interact. 1992 Nov 16;84(3):277-90. Unique Identifier : AIDSLINE MED/93046831; Rao CV; Desai D; Kaul B; Amin S; Reddy BS; Division of Nutritional Carcinogenesis, American Health; Foundation, Valhalla, New York.; Propolis, a honey bee hive product, is thought to exhibit a broad spectrum of activities including antibiotic, antiviral, anti-inflammatory and tumor growth inhibition; some of the observed biological activities may be due to caffeic acid (cinnamic acid) esters that are present in propolis. In the present study we syn
Lignified materials as medicinal resources. V. Anti-HIV (human immunodeficiency virus) activity of some synthetic lignins.: Chem Pharm Bull (Tokyo). 1992 Aug;40(8):2102-5. Unique Identifier : AIDSLINE MED/93046850; Nakashima H; Murakami T; Yamamoto N; Naoe T; Kawazoe Y; Konno K; Sakagami H; School of Medicine, Tokyo Medical and Dental University, Japan.; A class of synthetic lignins (dehydrogenation polymers of p-coumaric acid, ferulic acid, and caffeic acid) inhibited cytopathogenicity of HIV-1 and HIV-2 infection. The ratio of cytotoxic to anti-HIV (human immunodeficiency virus) doses depended strongly on conditions during polymer preparation. The activity increased
Determination of 2',3'-dideoxyinosine and 2',3'-dideoxyadenosine in rat plasma by high-performance liquid chromatography with precolumn fluorescence derivatization.: Chem Pharm Bull (Tokyo). 1992 Aug;40(8):2202-4. Unique Identifier : AIDSLINE MED/93046871; Nagaoka H; Nohta H; Saito M; Ohkura Y; Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka,; Japan.; A high-performance liquid chromatographic method with precolumn fluorescence derivatization using 2-(5-chlorocarbonyl-2-oxazolyl)-5,6-methylenedioxybenzofu ran is described for the quantification of 2 ,3 -dideoxyinosine, a therapeutic drug for acquired immunodeficiency syndrome, and 2 ,3 -dideoxyadenosine, an anti-hum
Kynostatin (KNI)-227 and -272, highly potent anti-HIV agents: conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine.: Chem Pharm Bull (Tokyo). 1992 Aug;40(8):2251-3. Unique Identifier : AIDSLINE MED/93046884; Mimoto T; Imai J; Kisanuki S; Enomoto H; Hattori N; Akaji K; Kiso Y; Department of Medicinal Chemistry, Kyoto Pharmaceutical; University, Japan.; Selective and potent HIV protease inhibitors containing allophenylnorstatine [Apns; (2S, 3S)-3-amino-2-hydroxy-4-phenylbutyric acid] as a transition-state mimic were designed and synthesized. Among them, conformationally constrained tripeptide derivatives, kynostati
A checklist of common oral manifestations of HIV infection.: Cleve Clin J Med. 1992 Nov-Dec;59(6):562, 565. Unique Identifier : AIDSLINE MED/93047215; Terezhalmy GT; Department of Dentistry, Cleveland Clinic Foundation, OH 44195.
Risk factors for HIV infection in homosexual men: the Cleveland men's study of risks in a low-prevalence area [see comments]: Cleve Clin J Med. 1992 Nov-Dec;59(6):573-80. Unique Identifier : AIDSLINE MED/93047216; Smucny J; Hom D; Ellner JJ; Carey JT; Houser HB; Calabrese LH; Edmonds K; Bowerfind E; Proffitt M; Yen-Lieberman B; et al; Department of Medicine, Case Western Reserve University School of; Medicine, Cleveland, OH 44106-4984.; Detailed questionnaires concerning alcohol and drug use, sexual practices, and medical history were completed by 301 homosexual men living in the Cleveland metropolitan area. Their sera were subsequently tested for antibodies to the human immunodeficiency virus. Fifty-six (18.6%) were seropositive. In a univariate ana
Obstacles to HIV prevention [editorial; comment]: Cleve Clin J Med. 1992 Nov-Dec;59(6):647-8. Unique Identifier : AIDSLINE MED/93047230; Koziol DE; Henderson DK
HIV seropositivity in association with pityriasis lichenoides et varioliformis acuta.: Clin Exp Dermatol. 1992 Jan;17(1):36-7. Unique Identifier : AIDSLINE MED/93047453; Ostlere LS; Langtry JA; Branfoot AC; Staughton RC; Department of Dermatology, Westminster Hospital, London, UK.; We describe a case of PLEVA in an asymptomatic, human immunodeficiency virus (HIV) positive patient. This association has not been previously described. The possible mechanisms involved are discussed.
Chronic actinic dermatitis with vitiligo-like depigmentation.: Clin Exp Dermatol. 1992 Jan;17(1):38-43. Unique Identifier : AIDSLINE MED/93047454; von den Driesch P; Fartasch M; Hornstein OP; Department of Dermatology, University Erlangen-Nurnberg,; Germany.; This report describes two patients suffering from severe chronic actinic dermatitis. Unusual widespread vitiligo-like depigmentation occurred during the course of the disease. The progression of these lesions was triggered by the chronic actinic dermatitis. Loss of pigment and complete absence of tyrosinase positive m
Disseminated granuloma annulare as a presentation of acquired immunodeficiency syndrome (AIDS).: Clin Exp Dermatol. 1992 Jan;17(1):60-2. Unique Identifier : AIDSLINE MED/93047461; McGregor JM; McGibbon DH; St John's Dermatology Centre, St Thomas' Hospital, London, UK.; Localized granuloma annulare is the commonest form of a granulomatous dermatosis characterized by flesh coloured or violaceous papules often arranged in rings. Several rare atypical variants are also reported including disseminated or generalized, subcutaneous and perforating types. There is a predilection for females
A gp120 HIV peptide with high similarity to HLA class II beta chains enhances PPD-specific and autoreactive T cell activation.: Clin Exp Immunol. 1992 Nov;90(2):170-4. Unique Identifier : AIDSLINE MED/93047468; Pugliese O; Viora M; Camponeschi B; Fei PC; Caprilli F; Chersi A; Evangelista M; Di Massimo AM; Colizzi V; Istituto Superiore di Sanita, Universita di Tor Vergata, Rome,; Italy.; The recent report that anti-gp120 antibodies can be induced by allogeneic stimuli in experimental animals in the absence of HIV, has focused attention on the structural similarities between gp120 and MHC. Here we report that some HIV+ individuals develop antibodies which similarly react with the gp120 HIV sequence (aa
Increased expression of IgG Fc receptor type I on neutrophils and monocytes from HIV-infected subjects.: Clin Exp Immunol. 1992 Nov;90(2):175-80. Unique Identifier : AIDSLINE MED/93047469; Capsoni F; Minonzio F; Ongari AM; Colombo G; Rizzardi GP; Bonara P; D'Arminio-Monforte A; Zanussi C; Institute of Internal Medicine, University of Milan, Italy.; Interferon-gamma (IFN-gamma) induces de novo expression of IgG Fc receptor type I (FcRI) on neutrophils and significantly raises the level of these receptors on monocytes. Since increased concentrations of IFN-gamma have been observed in sera from patients with HIV infection, FcRI expression might also be increased on
Natural killer (NK) cell activity during HIV infection: a decrease in NK activity is observed at the clonal level and is not restored after in vitro long-term culture of NK cells.: Clin Exp Immunol. 1992 Nov;90(2):181-7. Unique Identifier : AIDSLINE MED/93047470; Scott-Algara D; Vuillier F; Cayota A; Dighiero G; Immunopathology and Immunohaematology Service, Pasteur Institute,; Paris, France.; NK cell activity is impaired in HIV-infected patients. The mechanisms behind the altered NK functions are not clear, and conflicting data concerning NK and antibody-dependent cellular cytotoxicity (ADCC) activity have been reported. In order to investigate whether this impairment is also observed at the clonal level a
Selection of a muramyl peptide based on its lack of activation of nuclear factor-kappa B as a potential adjuvant for AIDS vaccines.: Clin Exp Immunol. 1992 Nov;90(2):188-93. Unique Identifier : AIDSLINE MED/93047471; Schreck R; Bevec D; Dukor P; Baeuerle PA; Chedid L; Bahr GM; Laboratorium fur Molekulare Biologie,; Ludwig-Maximilians-Universitat, Martinsried, Germany.; Activation of the cellular transcription factor nuclear factor-kappa B (NF-kappa B) by cytokines and other immunostimulants has been tightly linked with enhanced replication of human immunodeficiency virus-type 1 (HIV-1) in infected cells. Various immunomodulators are currently being examined in animal and human trial
[Botulinum toxin trial for spasticity]: Rinsho Shinkeigaku. 1992 Jun;32(6):637-8. Unique Identifier : AIDSLINE MED/93047555; Mezaki T; Kaji R; Kimura J; Department of Neurology, Kyoto University Hospital.; We treated three patients with spastic paraparesis with botulinum toxin (BTX). Two of them had scissors gait reflecting the hypertonus of adductors. In both, an injection of BTX to the responsible muscles improved gait, albeit transiently. The effect was shortlived, probably because increased tonus in non-injected por
Leuconostoc species bacteremia in a child with acquired immunodeficiency syndrome.: Clin Pediatr (Phila). 1992 Nov;31(11):699-701. Unique Identifier : AIDSLINE MED/93047616; Peters VB; Bottone EJ; Barzilai A; Hyatt AC; Blank S; Hodes DS; Department of Pediatrics, Mount Sinai School of Medicine, New; York, New York 10029.
HIV status in varicella pneumonia [letter; comment]: Clin Pediatr (Phila). 1992 Nov;31(11):703. Unique Identifier : AIDSLINE MED/93047619; Gorlick G
Evaluation of the in vivo effect of naproxen on zidovudine pharmacokinetics in patients infected with human immunodeficiency virus.: Clin Pharmacol Ther. 1992 Nov;52(5):464-70. Unique Identifier : AIDSLINE MED/93047638; Sahai J; Gallicano K; Garber G; Pakuts A; Hawley-Foss N; Huang L; McGilveray I; Cameron DW; Department of Medicine, Ottawa General Hospital, Ontario, Canada.; OBJECTIVE: To determine if therapeutic doses of naproxen affect the in vivo disposition of zidovudine. METHODS: This was designed as a randomized, two-period, two-treatment, crossover study. The patients were 12 men infected with human immunodeficiency virus who had acquired immunodeficiency syndrome (AIDS) or AIDS-re
High pentamidine levels associated with hypoglycemia and azotemia in a patient with Pneumocystis carinii pneumonia.: Diagn Microbiol Infect Dis. 1992 Aug;15(6):523-6. Unique Identifier : AIDSLINE MED/93047765; Comtois R; Pouliot J; Gervais A; Vinet B; Lemieux C; Department of Medicine, Notre-Dame Hospital, University of; Montreal, Canada.; We report on a patient who presented with a Pneumocystis carinii pneumonia. Intravenous pentamidine (4 mg/kg/day) was given for 14 days without the occurrence of adverse effects. During this treatment, the mean (+/- SD) serum pentamidine trough concentration was 94 +/- 16 ng/ml. Three days later, the patient was admit
Vertical transmission of human immunodeficiency virus type 1. Prognostic value of IgA antibody to HIV-1 polypeptides during pregnancy.: Diagn Microbiol Infect Dis. 1992 Aug;15(6):553-6. Unique Identifier : AIDSLINE MED/93047771; Re MC; Furlini G; Vignoli M; Ricchi E; Ramazzotti E; Bianchi S; Guerra B; Costigliola P; La Placa M; Institute of Microbiology, University of Bologna, Italy.; In a retrospective study of 31 pregnant women infected with human immunodeficiency virus type 1 (HIV-1), nine (29%) infants presented unequivocal signs of HIV-1 infection (persistent p24 antigenemia and/or positive virus isolation). All serum samples obtained from the others, during pregnancy and on delivery, were stu
Confidentiality and the HIV-positive patient.: Conn Med. 1992 Jul;56(7):398. Unique Identifier : AIDSLINE MED/93047934; Healey JM; Department of Community Medicine and Health Care, University of; Connecticut School of Medicine, Farmington.
Financial aspects of the provision of care to AIDS patients at Hartford Hospital.: Conn Med. 1992 Sep;56(9):467-8. Unique Identifier : AIDSLINE MED/93047935; Chupka LA; Birden HH Jr; Andrews L; School of Business Administration, University of Connecticut.; Data on the provision of care to persons with AIDS at Hartford Hospital are presented for the years 1988 and 1989. Approximately 2% of the total operating loss from uncompensated care at the hospital was due to patients with AIDS during both of those years. While the hospital continues to show a net surplus of revenue
Mononuclear phagocytes as targets, tissue reservoirs, and immunoregulatory cells in human immunodeficiency virus disease.: Curr Top Microbiol Immunol. 1992;181:239-63. Unique Identifier : AIDSLINE MED/93048145; Meltzer MS; Gendelman HE; Department of Cellular Immunology, Walter Reed Army Institute of; Research, Washington, DC 20307-5100.; We have presented evidence in this review for the following: 1. Macrophages are likely the first cell infected by HIV. Studies document recovery of HIV into macrophages in the early stages of infection in which virus isolation in T cells is unsuccessful and detectable levels of antibodies against HIV are absent. 2. Ma
Tuberculosis of the thymus.: Chest. 1992 Nov;102(5):1604-5. Unique Identifier : AIDSLINE MED/93048274; FitzGerald JM; Mayo JR; Miller RR; Jamieson WR; Baumgartner F; Department of Respiratory Medicine, University of British; Columbia, Vancouver General Hospital, Canada.; Tuberculosis is increasing in prevalence in North America, mainly due to HIV infection. We describe an unusual case of TB of the thymus in a HIV sero-negative Filipino immigrant who preoperatively was thought to have a thymoma. We describe the clinical, radiologic and pathologic findings and review the literature on T
Successful medical therapy of Rhodococcus equi pneumonia in a patient with HIV infection.: Chest. 1992 Nov;102(5):1619-21. Unique Identifier : AIDSLINE MED/93048282; Cury JD; Harrington PT; Hosein IK; University of Florida Health Science Center, University Medical; Center, Jacksonville.; A 34-year-old HIV-infected man was successfully treated with antimicrobial therapy alone for Rhodococcus equi pneumonia and has survived longer than six months. In the current literature, only two of seven HIV-infected patients so treated have survived as long as six months. Based on our experience and the available l
Thromboembolism associated with acquired immunodeficiency syndrome [letter]: Chest. 1992 Nov;102(5):1634. Unique Identifier : AIDSLINE MED/93048291; Pinilla J; Hill AR
[Transformation of a fistula into Kaposi's sarcoma of the rectum. A clinical follow-up over 7 years]: Chirurg. 1992 Oct;63(10):837-8. Unique Identifier : AIDSLINE MED/93048359; Schulz C; Neuhaus P; Chirurgische Klinik und Poliklinik, Universitatsklinikum Rudolf; Virchow, Freie Universitat Berlin.
Phenotypic characterization of isolated intraepithelial lymphocytes in patients with ulcerative colitis and normal controls.: Dig Dis Sci. 1992 Nov;37(11):1725-8. Unique Identifier : AIDSLINE MED/93048471; Hoang P; Senju M; Lowes JR; Jewell DP; Gastroenterology Unit, Radcliffe Infirmary, Oxford, UK.; A method was developed to isolate colonic intraepithelial lymphocytes in patients with ulcerative colitis (N = 8) and normal controls (N = 13) in order to characterize their phenotype using a panel of monoclonal antibodies and flow cytometry. In both groups, the majority of the cells are of the CD3+CD8+ phenotype asso
[Model of the spatial structure of the C-terminal fragment Thr-Thr-Asn-Tyr-Thr of peptide T, inhibiting the reproduction of the human immunodeficiency virus]: Dokl Akad Nauk. 1992;324(1):210-3. Unique Identifier : AIDSLINE MED/93048601; Andrianov AM; Verenich AI; Akhrem AA
[New perspectives in immunotherapy: adhesion molecules, superantigens, heat-shock proteins and cytokine antagonists]: Dtsch Med Wochenschr. 1992 Nov 13;117(46):1764-73. Unique Identifier : AIDSLINE MED/93048763; Gause A; Sahin U; Pfreundschuh M; Abteilung Innere Medizin I, Universitat des Saarlandes, Homburg.
Self-disclosure of HIV infection: preliminary results from a sample of Hispanic men.: Health Psychol. 1992;11(5):300-6. Unique Identifier : AIDSLINE MED/93049141; Marks G; Bundek NI; Richardson JL; Ruiz MS; Maldonado N; Mason HR; Department of Preventive Medicine, University of Southern; California, Los Angeles 90033.; We examined self-disclosure of HIV infection among 101 seropositive Hispanic men residing in Los Angeles. Results indicated that disclosure was highly selective and presumably influenced by the social, psychological, and material consequences of informing others about one s medical condition. Subjects tended to inform
High school students' perceptions of AIDS risk: realistic appraisal or motivated denial?: Health Psychol. 1992;11(5):307-16. Unique Identifier : AIDSLINE MED/93049142; Gladis MM; Michela JL; Walter HJ; Vaughan RD; Department of Psychiatry Medical College of Pennsylvania,; Philadelphia 19129.; We examined perceptions of risk for acquired immunodeficiency syndrome (AIDS) in 296 high school students living in or near a major urban center. We hypothesize