Danazol. A new perspective in the treatment of HTLV-1 associated myelopathy (preliminary report). NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

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Danazol. A new perspective in the treatment of HTLV-1 associated myelopathy (preliminary report).

Arq Neuropsiquiatr. 1992 Sep;50(3):402-3. Unique Identifier : AIDSLINE MED/93371196
Melo A; Moura L; Meireles A; Costa G; Departamento de Ciencias da Biorregulacao, Instituto de; Ciencias da Saude, Salvador BA, Brasil.

Abstract: We investigated the efficacy of danazol treatment in eight patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 patients. The improvement was noted within 15 days of danazol administration. Analysis of factors of relevance to the clinical improvement with danazol showed that the beneficial response was preferentially found in females.
Keywords: Adult Danazol/*THERAPEUTIC USE Drug Evaluation Female Human Male Middle Age Paraparesis, Tropical Spastic/*DRUG THERAPY JOURNAL ARTICLEKWDadultdanazol/KWDtherapeuticusedrugevaluationfemalehumanmalemiddleageparaparesis,tropicalspastic/KWDdrugtherapyjournalarticle
931230
M93C0789

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