[The neuropathological findings in the acquired immunodeficiency syndrome (AIDS): a review of 138 cases] NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


[The neuropathological findings in the acquired immunodeficiency syndrome (AIDS): a review of 138 cases]

Rev Soc Bras Med Trop. 1992 Apr-Jun;25(2):95-9. Unique Identifier : AIDSLINE MED/93391688
Wainstein MV; Ferreira L; Wolfenbuttel L; Golbspan L; Sprinz E; Kronfeld M; Edelweiss MI; Unidade de Doencas Infecciosas, Hospital de Clinicas de Porto; Alegre, Brasil.

Abstract: This is an autopsy study performed in a retrospective fashion to determine the incidence of diseases that could affect the central nervous system in AIDS. For this purpose, 138 autopsies of patients with AIDS performed at the Hospital de Clinicas de Porto Alegre, Brazil, between January/85 and December/90 were studied. All the brains were evaluated macroscopically and microscopically mainly through hematoxylin-eosin staining and if necessary special techniques like PAS, Grocott, Giemsa and Ziehl-Nielsen were done. Results have revealed 29 (21%) cases with cerebral toxoplasmosis; cryptococcosis in 17 (12%); tuberculosis in two (1%) and one case (0.7%) of candidiasis. Besides these inflammatory lesions, 15 (10%) presented vascular lesion; 8 (6%) had gliosis and 7 (5%) cases had suggestive findings of HIV encephalopathy. We can conclude that the CNS is a important target affected by AIDS and that cerebral toxoplasmosis is the principal disease in the CNS in AIDS patients.
Keywords: Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/*PATHOLOGY Autopsy/STATISTICS & NUMER DATA AIDS Dementia Complex/EPIDEMIOLOGY/PATHOLOGY AIDS-Related Opportunistic Infections/EPIDEMIOLOGY/PATHOLOGY Brazil/EPIDEMIOLOGY Central Nervous System/*PATHOLOGY Central Nervous System Diseases/EPIDEMIOLOGY/PATHOLOGY English Abstract Female Human Incidence Male Retrospective Studies JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/epidemiology/KWDpathologyautopsy/statistics&numerdataaidsdementiacomplex/epidemiology/pathologyaids-relatedopportunisticinfections/epidemiology/pathologybrazil/epidemiologycentralnervoussystem/KWDpathologycentralnervoussystemdiseases/epidemiology/pathologyenglishabstractfemalehumanincidencemaleretrospectivestudiesjournalarticle
931230
M93C0774

Copyright © 1993 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1993. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1993. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .