1993

Oral manifestations of AIDS. [videorecording].: [Chicago, Ill. : American Dental Association, 1988?] 1 videocassette (34 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9301486A; Robertson PB; (Producer) This program provides an overview of issues and relevant facts presented at an international symposium on AIDS in January 1988. The program involved a group of representatives from the international oral AIDS research community, academic dental community, directors of AIDS clinics, and representatives from
Presentations and complications of pediatric HIV infection. [videorecording]: [Houston, Tex. : UT/TV], c1992 1 videocassette (60 min.) : sd., col. ; 1/2 in (Pediatric grand rounds) Unique Identifier : AIDSLINE AV/9301460A; Kline M
HIV envelope and cell tropism : unexpected homogeneity of V3 region in macrophage tropic isolates from different patients. [videorecording]: [Bethesda, Md. : NIAID, 1993] 2 videocassettes (60 min., 38 sec.) : sd., col. ; 1/2 in (NIAID research grand rounds) Unique Identifier : AIDSLINE AV/9301391A; Chesebro BW
An:RNA virus, an RNA target, and RNA enzyme : HIV-1, TAR, ribozyme. [videorecording]: [Bethesda, Md. : NIAID, 1993] 2 videocassettes (1 hr., 6 min., 48 sec.) : sd., col. ; 1/2 in (NIAID research grand rounds) Unique Identifier : AIDSLINE AV/9301416A; Jeang K
A:policymaker's guide on AIDS.: Washington, D.C. : Intergovernmental Health Policy Project, George Washington University, c1989 30 p. : ill Unique Identifier : AIDSLINE CAT/9316120; Rowe M
The:Aids epidemic : private rights and the public interest.: Boston : Beacon Press, 1989 566 p. : ill Unique Identifier : AIDSLINE CAT/9316134; O'Malley P
AIDS in Michigan : HIV/AIDS five-year plan, 1991-1995 : a report of the Risk Reduction and AIDS Policy Commission to the Governor, the Legislature, and the Michigan Department of Public Health.: [Lansing] : The Department, [1991] iv, 60 p. : ill Unique Identifier : AIDSLINE CAT/9316155
HIV and AIDS-related suicidal behaviour : report on a WHO consulation, Bologna, September 22-23, 1990.: Bologna : Monduzzi editore, c1991 76 p. : ill Unique Identifier : AIDSLINE CAT/9316545; Beskow J
Prisons, HIV, and AIDS : risks and experiences in custodial care.: West Sussex : Avert, 1991 54 p. : ill Unique Identifier : AIDSLINE CAT/9316629; Turnbull PJ
AIDS prevention : what maternal and child health (MCH/FP) service providers need to know.: New Delhi : World Health Organization, Regional Office for South-East Asia, 1992 x, 43 p. : ill (Regional health paper, SEARP ; no. 23) Unique Identifier : AIDSLINE CAT/9316476
Documentation of the European Meeting of Self-Help Groups of People with HIV/AIDS, June 18-22, 1992. 1st ed.: Frankfurt/Main : Mabuse-Verlag, 1992 143 p. : ill Unique Identifier : AIDSLINE CAT/9316504
Searching for women : a literature review on women, HIV and AIDS in the United States. 3rd ed.: [Boston, Mass. (566 Columbus Ave., Boston 02118) : The Coalition], 1992 164 p Unique Identifier : AIDSLINE CAT/9316657; Kohn N; Community Service. Law Center; Community Service. Collaborative for Community Service and; Development
Acceptable risks.: New York : Poseidon Press, c1992 466 p Unique Identifier : AIDSLINE CAT/9316954; Kwitny J
Report on testing for AIDS : executive summary.: Toronto, Ont., Canada : The Commission, 1992 3, 3 p Unique Identifier : AIDSLINE CAT/9317217
[AIDS und die gesellschaftlichen Folgen.]: Frankfurt ; New York : Campus Verlag, c1993 236 p. : ill (Campus Forschung ; Bd. 704) Unique Identifier : AIDSLINE CAT/9316156; Eirmbter WH
Immune power : the comprehensive healing program for HIV. 1st ed.: New York : St. Martin's Press, c1993 xiii, 240 p Unique Identifier : AIDSLINE CAT/9316548; Kaiser JD
Queer blood : the secret AIDS genocide plot.: Los Angeles : Aries Rising Press, c1993 157 p Unique Identifier : AIDSLINE CAT/9316639; Cantwell A
A:Guide to selected HIV- and AIDS-related information services in the United States.: Rockville, Md. (P.O. Box 6003, Rockville 20849-6003) : CDC National AIDS Clearinghouse, [1993] v, 50 p Unique Identifier : AIDSLINE CAT/9316778
Blood, blood products, and HIV. 2nd ed.: London ; New York : Chapman & Hall Medical, 1994 ix, 276 p. : ill Unique Identifier : AIDSLINE CAT/9316728; Madhok R; Forbes CD; Evatt BL
Modeling the AIDS epidemic : planning, policy, and prediction.: New York, NY : Raven Press, c1994 xxix, 624 p. : ill Unique Identifier : AIDSLINE CAT/9317137; Kaplan EH; Brandeau ML
Active specific immunotherapy (ASI) of cancer using synthetic cancer-associated carbohydrate antigens (Meeting abstract).: Anticancer Res; 12(6A):1871-2 1992. Unique Identifier : AIDSLINE ICDB/93696346; Reddish M; Longenecker BM; MacLean GD; Biomira Inc., Edmonton, Alberta, Canada; We have focused our efforts on delineating cancer-associated epitopes expressed on carcinoma cell surface mucin molecules for use in ASI. We used entirely synthetic carbohydrate, peptide, and glycopeptide epitopes expressed on carcinoma cell surface mucin molecules; formulated them into immunotherapeutic vaccines ; a
Stimulation of peripheral blood mononuclear cells (PBMNCs) from chronic lymphatic leukemia (CLL) patients by an antisense phosphorothioate oligomer to the rev gene of HIV (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A2713 1993. Unique Identifier : AIDSLINE ICDB/93693657; Branda RF; Moore AL; Mathews L; McCormack JJ; Zon G; Dept. of Medicine, Vermont Cancer Center, Univ. of Vermont,; Burlington, VT 05401; Serious infections are frequent complications of CLL. We observed that an antisense oligomer designed to treat HIV infection caused splenomegaly and hypergammaglobulinemia in mice. This anti-rev 27-mer also is a potent B-cell mitogen and induces production of high titers of IgM and IgG in normal mice in vivo, and in n
Adult T-cell leukemia and spastic paraparesis in south India: molecular epidemiology of HTLV-I (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A3239 1993. Unique Identifier : AIDSLINE ICDB/93694195; Nerurkar VR; Song KJ; Babu PG; Saraswathi NK; Chandy M; John TJ; Yanagihara R; NIH, Bethesda, MD 21702; Until recently, the occurrence of human T-lymphotropic virus type I (HTLV-I) infection and disease was controversial in India . We have recently identified cases of HTLV-I-associated adult T-cell leukemia and spastic paraparesis among residents of south India. Our serological surveys
Homology of human immunodeficiency virus 1 (HIV-1) sequences to human DNA mapped by in situ hybridization (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A3240 1993. Unique Identifier : AIDSLINE ICDB/93694196; Popescu NC; Zimonjic DB; DiPaolo JA; Lab. of Biology, NCI, Bethesda, MD 20892; To map the virus integration site in a human T-cell line (ACH-2) with a single copy of defective virus, chromosomes were hybridized with a biotinylated HIV-1 DNA probe (Oncor, Gaithersburg, MD). The HIV integration was localized on the short arm of chromosome 7 but several other chromosomes exhibited signal at the cen
Characterization of LP-BM5 defective retrovirus-induced T-cell lymphomagenesis in murine acquired immunodeficiency disease (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A3257 1993. Unique Identifier : AIDSLINE ICDB/93694216; Campbell-Washington J; Eiseman JL; MacAuley C; Sentz D; Univ. of Maryland Cancer Center, Baltimore, MD 21201; Murine acquired immunodeficiency syndrome (MAIDS) is induced by infection of susceptible mice (ie, C57BL/6) with LP-BM5, a mixture of murine leukemia viruses (MuLV). The syndrome is characterized by severe immunodeficiency and lymphoproliferation termed MAIDS because of its similarity to human AIDS. Preliminary result
Analysis of mice with mutations in the tumor-suppressor genes RB, NF-1 and p53 (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:610-1 1993. Unique Identifier : AIDSLINE ICDB/93694365; Jacks T; Dept. of Biology, Center for Cancer Res., Massachusetts Inst. of; Technology, Cambridge, MA 02139; The homozygous inactivation of tumor-suppressor genes is a common event in the genesis of a large number of human cancers. In addition, individuals who inherit a defective allele of one of several tumor suppressor genes are strongly predisposed to malignancy. In an effort to understand the tumorigenic effects of tumor
HIV-associated lymphoma of the gastrointestinal tract (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A1 1993. Unique Identifier : AIDSLINE ICDB/93694401; Imrie K; Sawka C; Kutas G; Burkes R; Warner E; Brandwein J; Shepherd F; Univ. of Toronto, Toronto, Canada; Non-Hodgkin s lymphoma occurring in HIV-infected patients (pts) has a predilection for extranodal sites. We report a series of 24 pts (23 male, 1 female) with HIV-associated GI lymphoma. Their median age was 38 yr (range 24-59). HIV infection antedated the development of lymphoma by 0-108 mo and lymphoma was the AIDS
Infusional cyclophosphamide, doxorubicin, and etoposide (CDE) in HIV- and HTLV-I-related non-Hodgkin's lymphoma (NHL): a highly active regimen (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A3 1993. Unique Identifier : AIDSLINE ICDB/93694403; Sparano JA; Wiernik PH; Strack M; Leaf A; Albert Einstein Cancer Center, Bronx, NY 10467; 18 patients (pts) with HIV- (n=16) or HTLV-I-related (n=2) NHL received a cumulative dose of C (750 mg/m2), D (50 mg/m2), and E (240 mg/m2) given as a continuous iv infusion over 4 days, repeated every 28 or more days. All HIV+ pts had at least one poor prognostic feature associated with a median survival of 2.2-4.2 m
A Phase 1/2 study of recombinant platelet factor 4 (rPF4) in patients with AIDS-related Kaposi's sarcoma (KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A4 1993. Unique Identifier : AIDSLINE ICDB/93694404; Kahn J; Ruiz R; Kerschmann R; Berger T; Ma R; Coleman R; Alford BL; San Francisco General Hosp., San Francisco, CA 94110; Kaposi s sarcoma remains a significant clinical problem for patients (pts) infected with HIV. Recently, rPF4 was cloned and expressed in E coli. rPF4 demonstrates inhibition of angiogenesis and inhibits the of growth KS cells in vitro. A Phase 1/2 study was begun to determine the safety and preliminary effectiveness o
Excess risk of leukemia among persons with the acquired immune deficiency syndrome (AIDS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A5 1993. Unique Identifier : AIDSLINE ICDB/93694405; Manns A; Cote T; Biggar R; Blattner W; NACMR Study Group, NCI, Bethesda, MD 20892; Since leukemia occurs in the setting of immune deficiency, we evaluated the possibility that leukemias may occur at increased frequency in persons with AIDS compared to the general population. Cancer and AIDS registries were linked in four States and age-, sex-, and race-adjusted expected (Exp) numbers of leukemias, i
All-trans-retinoic acid (TRA) in the treatment of AIDS-related kaposi's sarcoma (Kaposi's sarcoma: a Phase II Illinois Cancer Center Study) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A6 1993. Unique Identifier : AIDSLINE ICDB/93694406; Von Roenn J; von Gunten C; Mullane M; French S; Blough R; Benson AB; Illinois Cancer Center, Chicago, IL 60604; TRA is a major endogenous metabolite of vitamin A which induces differentiation and/or growth inhibition in many tumorigenic cell lines. TRA is associated with suppression of both the IL-6 receptor alpha chain and IL-6 secretion and inhibits AIDS KS cells from proliferating in culture. 14 patients (pts) with AIDS-rela
Quantitative ultrasound volume measurement serves as noninvasive method to follow response of cutaneous Kaposi's sarcoma lesions to Doxil therapy (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A7 1993. Unique Identifier : AIDSLINE ICDB/93694407; Goebel FD; Bogner JR; Spathling S; Held M; Sandor P; Trubenbach K; Rauch C; Kronawitter U; Medizinische Poliklink, Univ. of Munich, Germany; Objective: Within the context of a Phase II study of Doxil (Stealth liposomal doxorubicin), we sought to develop and validate an ultrasound method to quantify the response of cutaneous KS lesions to therapy, and to confirm complete response (CR) without the need for biopsy. Methods: 38 patients (pts) with advanced KS
Pharmacokinetics (PK), tumor localization (TL), and safety of Doxil (liposomal doxorubicin) in AIDS patients with Kaposi's sarcoma (AIDS-KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A8 1993. Unique Identifier : AIDSLINE ICDB/93694408; Northfelt DW; Martin FJ; Kaplan LD; Russell J; Anderson M; Lang J; Volberding PA; AIDS Program, Univ. of California, San Francisco, CA 94143; Objectives: To compare the PK, TL, and safety of comparable single doses of Adriamycin (A) and Doxil in patients with AIDS-KS. Methods: Subjects with AIDS-KS were prospectively randomized to receive a single dose of either A or Doxil, 6 subjects at 10 mg/m2, 6 at 20 mg/m2, and 4 at 40 mg/m2. Plasma drug levels were me
Radiotherapy (RT) for bronchopulmonary AIDS-related Kaposi's sarcoma (KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A9 1993. Unique Identifier : AIDSLINE ICDB/93694409; Routy JP; Methot F; Simard P; Beaulieu R; Toma E; Dumont M; Centre de recherche, Hotel-Dieu Hosp., Montreal, Quebec H2W 1T8,; Canada,; The aim of this prospective study was to evaluate the efficacy and tolerance of thoracic RT for bronchopulmonary KS, in patients (pts) who never received chemotherapy. Between September 1990 and September 1992, 17 male pts with lung biopsy-proven KS, and/or positive bronchoscopy findings were included. Ten had experie
Systemic hyperthermia in the treatment of HIV-related Kaposi's sarcoma (KS) confers a survival advantage: long-term results of a Phase I study (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A10 1993. Unique Identifier : AIDSLINE ICDB/93694410; Alonso K; Pontiggia P; de Bartolomei E; Calvi G; Cuppone Curto F; Nardi C; Lab. Atlanta, Clinica 'Citta di Pavia,' Italy; Treatment of HIV-related KS with antiretrovirals, interferon-a, and antineoplastics has not affected survival. Immunologic impairment is the critical factor in disease progression. Now, we report long-term results in 29 men, 2 women with profound immunologic impairment and disseminated KS (median duration, 12 mo) and
CMV retinitis and quality of life (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A11 1993. Unique Identifier : AIDSLINE ICDB/93694411; Perlis C; Wallace D; Rosenbaum E; Univ. of California/Mount Zion Hosp., 1600 Divisidaro, San; Francisco, CA 94120; A series of 50 patients (pts) diagnosed with HIV have been visited by the director of the art for recovery program (AFRP) with the objective of enhancing their quality of life through artistic expression. Many patients (pts) present with additional diagnoses, of those, pts with
Non-AIDS-defining malignancies occurring in individuals who have immunodeficiency virus infection (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A14 1993. Unique Identifier : AIDSLINE ICDB/93694414; Toi M; Myers AM; Univ. of Colorado Health Sciences Center, Denver, CO 80204; 28 non-AIDS-defining malignancies occurring in 27 individuals with human immunodeficiency virus infection were identified at the University of Colorado Health Sciences Center and its affiliated hospitals from 1988 through 1992. An individual with both Hodgkin s disease and malignant melanoma was seen in 1984. The age
Effect of simultaneous AZT and hydroxyurea (HU): study in an HL-60 model system (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A15 1993. Unique Identifier : AIDSLINE ICDB/93694415; Nusbaum NJ; Joseph P; Lee Streich Flow Cytometry Lab., Hematology/Oncology Div.,; Brookdale Hosp. Medical Center, Brooklyn, NY 11212; Patients (pts) with AIDS-related neoplasms may be considered for treatment with AZT , other antiretroviral agents, therapy for opportunistic infections, and/or cancer chemotherapy. These multiple medications are often poorly tolerated in this pt popula
Kaposi's sarcoma in AIDS (EKS) patients: proposal for a new staging classification based on TNM-UICC recommendations (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A16 1993. Unique Identifier : AIDSLINE ICDB/93694416; Tambussi G; Torri W; Repetto L; Saracco A; Moresco L; Lazzarin A; Badellino F; Gruppo Italiano di Cooperazione AIDS e Tumori (GICAT), Italy; Objective: several proposals for EKS classification have been made; however,generally accepted criteria are lacking. According to TNM-UICC indications for tumor staging,we propose a new classification system based on a modified Krown s staging which takes into account three major parameters: T, anatomical and morpholo
Difference in the trend of cancer in AIDS patients at Cook County Hospital (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A17 1993. Unique Identifier : AIDSLINE ICDB/93694417; Mullai N; Yusoof S; Ahmed Z; Shiomoto G; Gunter T; Cook County Hosp. (CCH), Chicago, IL 60612; Recently, a change of trend is noticed nation wide in the incidence of lymphoma and Kaposi s sarcoma (KS) in AIDS patients (pts). Contrary to the increase in lymphoma and decrease in KS, a different pattern is observed in the urban inner city population of CCH. Since 1985 until July 1992, a total of 196 cases of lymph
Phase II trial of low-dose oral etoposide in AIDS-related Kaposi's sarcoma (KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A19 1993. Unique Identifier : AIDSLINE ICDB/93694419; Sander E; Zampese M; Prolla G; Marques A; Jung F; Venegas LF; Sprinz E; Kronfeld M; Kalakun L; Mans DA; et al; South-American Office for Anticancer Drug Development, Hosp. de; Clinicas de Porto Alegre, Brazil; Etoposide is a topoisomerase II inhibitor whose antitumor activity in preclinical models appears to be schedule-dependent. Notably prolonged drug administration was shown to improve treatment results in patients (pts) with tumors such as small cell lung cancer. In this Phase II trial, oral etoposide was given at the d
Survival (S) impact of different factors in AIDS patients (pts): retrospective analysis (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A21 1993. Unique Identifier : AIDSLINE ICDB/93694421; Schmilovich A; Cahn P; Perez H; Gil Deza E; Huesped Foundation, Gascon 79, (1181) Buenos Aires, Argentina; Between February 1983 and November 1992, 387 AIDS pts according to CDC classification system were assisted al Fernandez Hospital and Huesped Foundation. 296/387 had opportunistic infections (OI), 67/387 had Kaposi s sarcoma (KS) and 16/387 had non-Hodgkin s lymphomas (NHL) as initial disease. Eight pts were inevaluabl
AIDS and malignancy: experience of an inner city primary care hospital (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A22 1993. Unique Identifier : AIDSLINE ICDB/93694422; Savona S; Ohri A; Lakkis W; Salloum E; Garcia N; Hewlett D; Lincoln Hosp., Bronx, NY 10451; Lincoln Hospital is a primary care institution in the South Bronx where the in-hospital HIV rate is estimated at 10%. The major risk factors for HIV infection are iv drug use in 70%, heterosexual contact in 20%, homosexual contact in 5% and blood product associated in 5%. The HIV registry consists of patients (pts) si
Intracarotid chemotherapy (ICCT) with etoposide and cisplatin in patients (pts) with poor prognosis HIV-related CNS non-Hodgkin's lymphoma (HIV-CNS-NHL) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A23 1993. Unique Identifier : AIDSLINE ICDB/93694423; Madajewicz S; Fuhrer J; Chowhan N; Roche P; Heller H; Steigbigel R; Mariuz P; Hentschel P; SUNY, Stony Brook, NY 11794; Between January 1991 and December 1991, 5 pts with high-grade HIV-CNS-NHL and 1 pt with non-HIV-CNS-NHL entered on a protocol of ICCT (Cancer 67:2844-9, 1991). All HIV-positive pts were on AZT therapy at the time of CNS-NHL diagnosis. All of them had
In vitro model of Kaposi's sarcoma (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A3237 1993. Unique Identifier : AIDSLINE ICDB/93694193; Moyer MP; Cantu AA; Anderson LS; Torres R; Cagle MP; Jenson HB; Univ. of Texas Health Science Center, San Antonio, TX 78284.; Primary cultures of human submucosal mesenchymal (SM) cells from the intestine infected with the human immunodeficiency virus (HIV) displayed Kaposi s sarcoma (KS)-like changes in growth and morphology. More IL-6 was released from HIV-infected than control cultures at early times (3-6 days postinfection) even though v
Treatment of poor prognosis epidemic Kaposi's sarcoma (KS) with doxorubicin, bleomycin, vindesine and recombinant human granulocyte-monocyte colony-stimulating factor (rGM-CS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A2 1993. Unique Identifier : AIDSLINE ICDB/93694402; Bakker PJ; Danner SA; ten Napel CH; van Leusen RM; Muusers JA; Veenhof CH; Div. of Medical Oncology, Academic Medical Center, Center,; Amsterdam, The Netherlands; Chemotherapy with doxorubicin, bleomycin and vincristine has been reported to result in high response rates and durable remissions in patients (pts) with KS. This treatment has, however, significant side effects such as myelosuppression neurotoxicity. Infectious complications have been reported in approx 40% and neuro
HIV-related non-Hodgkin's lymphoma: CHOP-induction and AZT/IF alpha-maintenance therapy (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A12 1993. Unique Identifier : AIDSLINE ICDB/93694412; Huhn D; Weiss R; Nerl C; Mitrou S; Schurmann D; Arasteh K; Kronawitter U; Becker K; van Lunzen J; UKRV, Berlin, Germany; In a pilot study, induction therapy with CHOP and maintenance therapy with IF alpha and AZT were tested. High- and normal-risk patients (pts) were identified. Methods: High risk, 2 of 3 criteria: T4 less than 50 ul; WHO PS 3 + 4; opportunistic infecti
Treatment of HIV-related non-Hodgkin's lymphoma (NHL) with chemotherapy (CT) and G-CSF: reduction in the days of hospitalization and toxicity with concomitant overall reduction in the cost (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A13 1993. Unique Identifier : AIDSLINE ICDB/93694413; Tirelli U; Errante D; Vaccher E; Tavio M; Accurso V; Bernardi D; Talamini R; Spina M; Div. of Medical Oncology and AIDS Program, Italy; Treatment of HIV-related NHL with CT is associated with an increased risk of side effects, in particular bone marrow toxicity. The aim of this study is to compare the toxicity and the cost of CT with G-CSF vs CT without G-CSF. We have analyzed 37 consecutive patients (pts) treated with intensive CT regimens, 19 pts fr
Phase II trial of pentosan polysulfate (PPS) in patients (pts) with AIDS-related Kaposi's sarcoma (KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A18 1993. Unique Identifier : AIDSLINE ICDB/93694418; Schwartsmann G; Sander E; Prolla G; Sprinz E; Zampese M; Vinholes J; Jung F; Kronfeld M; Kalakun L; Mans DA; et al; South-American Office for Anticancer Drug Development, Hospital; de Clinicas de Porto Alegre, Brazil; Basic fibroblast growth factor (b-FGF) is a protein which has been shown to stimulate angiogenesis. Inhibition of b-FGF was shown to block this phenomenon in several tumor models. KS is a highly angiogenic tumor which expresses in culture a protein (K-FGF) that acts in the same receptor as FGF. In this Phase II clinic
The role of G-CSF in zidovudine-induced leukopenia and granulocytopenia (G) in AIDS patients (pts): results of a pilot study (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 12:A20 1993. Unique Identifier : AIDSLINE ICDB/93694420; Katz A; Levy GC; Albert Einstein Hosp., Sao Paulo, Brazil; AIDS pts often develop leukopenia and G, either related to the HIV infection itself or associated with the use of myelosupressive drugs such as AZT , cytotoxic chemotherapy or DHPG. This common event may prevent the use of these agents or require its t
[On the issue of organizing medical care for HIV infections (letter)]: Pol Tyg Lek. 1991 Aug 26-Sep 2;46(35-36):675-6. Unique Identifier : AIDSLINE MED/93391140; Halota W; Gizinski W; Kliniki Chorob Zakaznych AM.
The legal ramifications of AIDS.: CDS Rev. 1992 Dec;85(11):24-30. Unique Identifier : AIDSLINE MED/93364992; Asa R
AIDS and hepatitis--some facts and practical methods for prevention of infection in dental operatory [editorial]: J Indian Soc Pedod Prev Dent. 1992 Mar;10(1):2p. Unique Identifier : AIDSLINE MED/93367573; Chawla HS
Establishment and maintenance of bovine leukosis virus-free farm.: Kitasato Arch Exp Med. 1992 Sep;65(2-3):137-41. Unique Identifier : AIDSLINE MED/93368105; Yoshikawa H; Yoshikawa T; Oyamada T; Sasaki T; Koyama H; Tsubaki S; Department of Veterinary Pathology, School of Veterinary Medicine; and Animal Sciences, Kitasato University, Aomori, Japan.
Immune recognition of human T-cell leukemia virus type-I (HTLV-I) by MHC-restricted cytotoxic T lymphocytes.: Kitasato Arch Exp Med. 1992 Sep;65(2-3):79-85. Unique Identifier : AIDSLINE MED/93368109; Tanaka Y; Department of Immunology, School of Hygienic Sciences, Kitasato; University, Kanagawa, Japan.; In our studies, it was demonstrated for the first time that HTLV-I gag and pX, and env and pX antigens are the target antigens recognized by CD8+ CTL in association with RT-1k and RT-1l class I antigens, respectively, in the rat system. Furthermore, the gag-expressing rVV and the env-expressing rVV were shown to have
Chronic cutaneous lupus erythematosus and subsequent infection with HIV1.: Mater Med Pol. 1992 Jan-Mar;24(1):21-3. Unique Identifier : AIDSLINE MED/93368222; Montero A; Jorfen M; Arpini R; Universidad Nacional De Rosario, Argentina.; Since the beginning of the pandemia caused by the Human Immunodeficiency Virus several reports have described cases of infection by HIV1 in patients bearing rheumatic diseases. The infection by HIV 1 in patients with Systemic Lupus Erythematosus (SLE) and Chronic Cutaneous Lupus Erythematosus (CCLE), however, seems to
Modified orthodontic treatment goals in a patient with multiple complicating factors.: Spec Care Dentist. 1992 Nov-Dec;12(6):251-4. Unique Identifier : AIDSLINE MED/93369741; Williams BJ; Department of Dental Medicine, Children's Hospital and Medical; Center, Seattle, WA 98105.; This paper reviews orthodontic care in patients who are in nontraditional categories. Specific orthodontic management of a patient who had severe hemophilia, seropositivity for anti-HIV Ab, and Hepatitis B surface antigen is reviewed. The importance of defining acceptable treatment goals in these patients is of paramo
Interleukin-6 and granulocyte macrophage-CSF in the cerebrospinal fluid from HIV infected subjects with involvement of the central nervous system.: Arq Neuropsiquiatr. 1992 Jun;50(2):180-2. Unique Identifier : AIDSLINE MED/93371156; Perrella O; Guerriero M; Izzo E; Soscia M; Carrieri PB; D. Cotugno Hospital for Infectious Diseases, Naples.; We detected the cytokines interleukin-6 (IL-6) and granulocyte macrophage-CSF (GM-CSF) by ELISA in the CSF and serum of 30 HIV-infected patients classified as AIDS dementia complex (ADC), and 20 subjects with other neurological diseases (OND). We have found a high incidence of dete
Evidence of preferential female prevalence of HTLV-I associated tropical spastic paraparesis in Bahia-Brazil.: Arq Neuropsiquiatr. 1992 Jun;50(2):183-8. Unique Identifier : AIDSLINE MED/93371157; Moreno-Carvalho OA; Santos JI; Di Credico G; Galvao-Castro B; Fundacao Jose Silveira-LCR, Brasil.; In order to evaluate the prevalence of HTLV-I infection and its association with tropical spastic paraparesis (TSP) in Bahia, a Northeastern State of Brazil , CSF and sera from TSP patients and CSF and/or sera from some selected groups of individuals were studied. The results seem t
HTLV-I associated myelopathy in Salvador (northeastern Brazil).: Arq Neuropsiquiatr. 1992 Jun;50(2):189-90. Unique Identifier : AIDSLINE MED/93371158; Meireles A; Moreira Junior ED; Moreno-Carvalho OA; Badaro R; Melo A; Santo Antonio Hospital, HSA.; Recent studies of tropical spastic paraparesis have confirmed the existence of human T-cell leukemia virus type-1 (HTLV-I) in several tropical areas of the world. In order to determine the role of HTLV-I as an etiologic agent of myelopathies in Salvador, we conducted a clinical and serological study in 43 patients wit
[Plasmapheresis in neurology. Critical analysis of indications and protocols]: Arq Neuropsiquiatr. 1992 Sep;50(3):324-8. Unique Identifier : AIDSLINE MED/93371182; Seggia JC; Abreu P; Hospital dos Servidores do Estado INAMPS-RJ, Brasil.; Therapeutic plasmapheresis (plasma exchange) in neurology is a matter of discussion. We review the main articles on clinical trials, both controlled and uncontrolled, trying to establish the efficacy and safety of the procedure. Humoral aspects involved in the genesis of the disorder play an important role for its ind
Acute central nervous system infection by Trypanosoma cruzi and AIDS.: Arq Neuropsiquiatr. 1992 Sep;50(3):375-7. Unique Identifier : AIDSLINE MED/93371190; Gallo P; Fabiao Neto OM; Suarez JM; Borba RP; The acute infection of the CNS by Trypanosoma cruzi acquired by blood transfusion is uncommon. The concomitance of AIDS in the patient reported shows the importance of cellular immunity in restriction of this parasite, and reinforces the problem of blood transfusion in endemic zones.
Danazol. A new perspective in the treatment of HTLV-1 associated myelopathy (preliminary report).: Arq Neuropsiquiatr. 1992 Sep;50(3):402-3. Unique Identifier : AIDSLINE MED/93371196; Melo A; Moura L; Meireles A; Costa G; Departamento de Ciencias da Biorregulacao, Instituto de; Ciencias da Saude, Salvador BA, Brasil.; We investigated the efficacy of danazol treatment in eight patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 patients. The improvement was noted within 15 days of danazol admi
[Gene amplification for the diagnosis of HIV infection]: Rev Roum Virol. 1992 Jul-Dec;43(3-4):207-20. Unique Identifier : AIDSLINE MED/93372002; Cernescu C; Ruta S; Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.
[The chemical therapy of HIV infections. Strategies, results, prospects]: Rev Roum Virol. 1992 Jul-Dec;43(3-4):221-66. Unique Identifier : AIDSLINE MED/93372003; Esanu V; Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.
Transmission of HIV by transfusion of HIV-screened blood: the value of a national register. The 'Recipients' Study Group of the French Society of Blood Transfusion.: Transfus Med. 1992 Mar;2(1):51-5. Unique Identifier : AIDSLINE MED/93373007; Courtois F; Jullien AM; Chenais F; Noel L; Pinon F; Poste de Transfusion Sanguine, Hopital Beaujon, CLICHY.; A National Register of transfusion-transmitted infections was opened by the French Society of Blood Transfusion on 1 October, 1986. Out of 54 initially reported cases of HIV-infection, allegedly transmitted by blood components, further investigation could be completed in 33 cases. The transfusional origin of contamina
AIDS-the Indian scene [editorial; comment]: J Assoc Physicians India. 1992 Aug;40(8):507-8. Unique Identifier : AIDSLINE MED/93374779; Rodrigues J
Rising trend of HIV infection with special reference to blood donors [see comments]: J Assoc Physicians India. 1992 Aug;40(8):513-5. Unique Identifier : AIDSLINE MED/93374782; Wadia MR; Karve SR; Blood Bank, Department of Pathology, Ruby Hall Clinic, Pune.; This paper describes the experience in testing for antibodies to the human immunodeficiency virus (anti-HIV) at a private institution. A total of 31,003 persons were tested between August 1986 and June 1990 including 20, 321 blood donors. The other 10,712 were visitors to the Ohso International Commune (OIC), a commun
Similar data different interpretations [letter; comment]: J Assoc Physicians India. 1992 Aug;40(8):555-6. Unique Identifier : AIDSLINE MED/93374806; Kulkarni V
Modeling AIDS vaccines: the cellular level.: Mem Inst Oswaldo Cruz. 1992 Jan-Mar;87(1):103-13. Unique Identifier : AIDSLINE MED/93375869; Struchiner CJ; Halloran ME; GRIS, Universite de Montreal, QC Canada.; This paper discusses current strategies for the development of AIDS vaccines which allow immunization to disturb the natural course of HIV at different detailed stages of its life cycle. Mathematical models describing the main biological phenomena (i.e. virus and vaccine induced T4 cell growth; virus and vaccine induc
Rapid in vitro detection of HIV-1-specific antibody secretion by cells-culture with virus antigens.: Mem Inst Oswaldo Cruz. 1992 Apr-Jun;87(2):239-47. Unique Identifier : AIDSLINE MED/93375900; Caterino-de-Araujo A; Secao de Imunologia, Instituto Adolfo Lutz, SP, Brasil.; The present report describes an alternative method for in vitro detection of HIV-1-specific antibody secretion in 24h of culture employing as stimulant of peripheral blood mononuclear cells the disrupted inactivated whole virus adsorbed onto microwells in a commercial ELISA kit plates. The results obtained from this t
Antigens of Toxoplasma gondii in a AIDS patient urine detected by coagglutination.: Mem Inst Oswaldo Cruz. 1992 Apr-Jun;87(2):303-4. Unique Identifier : AIDSLINE MED/93375904; Fachado A; Fonte L; Alvarez A; Alberti E; Finlay CM; Departamento de Protozoologia, Instituto de Medicina Tropical; Pedro Kouri, Ciudad de La Habana, Cuba.
Western blotting for HIV-antibody confirmation in blood donors: an improved approach by recombinant immunoblots [letter]: Transfus Med. 1992 Sep;2(3):249-50. Unique Identifier : AIDSLINE MED/93386336; Das PC; de Vries AH; McShine RL; Smit Sibinga CT
Parallels between AIDS, leprosy and syphilis [see comments]: Hawaii Med J. 1992 Nov;51(11):300, 302, 304. Unique Identifier : AIDSLINE MED/93388220; Veith I
[HTLV-1 infection in polytransfused patients (letter)]: Medicina (B Aires). 1992;52(2):185-7. Unique Identifier : AIDSLINE MED/93390311; Planes N; Pirola D; Sen L; Miani Abreu S; Penalver J; Estevez ME
Chemotherapy and immunity in opportunistic parasitic infections in AIDS.: Parasitology. 1992;105 Suppl:S93-101. Unique Identifier : AIDSLINE MED/93390999; Zumla A; Croft SL; Center for Infectious Diseases, University of Texas, School of; Medicine and Public Health, Houston.; Parasitic diseases are endemic in parts of the tropics, but there is no convincing evidence that their prevalence or incidence is increasing due to the HIV epidemic. Available scientific data on parasitic infections in patients with the Acquired Immunodeficiency Syndrome (AIDS) suggests a predominance of Pneumocystis
HTLV-II and a new endemic area for HTLV-I in Brazil.: Rev Soc Bras Med Trop. 1992 Apr-Jun;25(2):141-3. Unique Identifier : AIDSLINE MED/93391683; Moreira Junior ED; Harrington Junior W; Ribeiro TT; Melo A; Brites C; Badaro R; Swanson P; Lee H; Laboratorio de Retrovirus, Hospital Universitario Professor; Edgard Santos, Universidade Federal da Bahia, Salvador, Brasil.
[The neuropathological findings in the acquired immunodeficiency syndrome (AIDS): a review of 138 cases]: Rev Soc Bras Med Trop. 1992 Apr-Jun;25(2):95-9. Unique Identifier : AIDSLINE MED/93391688; Wainstein MV; Ferreira L; Wolfenbuttel L; Golbspan L; Sprinz E; Kronfeld M; Edelweiss MI; Unidade de Doencas Infecciosas, Hospital de Clinicas de Porto; Alegre, Brasil.; This is an autopsy study performed in a retrospective fashion to determine the incidence of diseases that could affect the central nervous system in AIDS. For this purpose, 138 autopsies of patients with AIDS performed at the Hospital de Clinicas de Porto Alegre, Brazil , between Ja
[Candidiasis in AIDS patients]: Rev Soc Bras Med Trop. 1992 Jul-Sep;25(3):165-9. Unique Identifier : AIDSLINE MED/93391691; Campos CE; Igreja RP; Campos EP; Depto. de Microbiologia e Imunologia, Universidade Estadual; Paulista, Botucatu, SP, Brasil.; A total of 35 in patients admitted at Emilio Ribas Hospital--Sao Paulo, Brazil , with digestive candidiasis and AIDS clinical diagnostic were evaluated 10 month later, being 29 male and 6 female; white outnumbering black with age ranged from 30 to 50 years old. Agar Sabouraud cultur
[Rheumatic diseases associated with HIV infection (letter)]: Rev Rhum Mal Osteoartic. 1992 Dec;59(12):842. Unique Identifier : AIDSLINE MED/93391917; Taillan B; Garnier G; Ferrari E; Fuzibet JG; Quaranta JF; Gratecos N; Dujardin P
[Factors associated with the failure to use condoms among a population of parenteral drug addicts]: Acta Psiquiatr Psicol Am Lat. 1992 Sep;38(3):245-9. Unique Identifier : AIDSLINE MED/93392681; Gutierrez Fraile M; Ballesteros J; Garcia E; Toribio O; Universidad del Pais Vasco, Departamento de Neurociencias,; Hospital Santiago Apostol, Vitoria, Espana.; Use of condom in sexual intercourse by intravenous drug users has been assessed among a clinical population (n = 139). The multiple logistic regression results show that being a female (OR = 5.1, 95% CI = 2.0-13.2), on drug dependence for a 5-year period or more (OR = 3.0; 95% CI = 1.3-6.9) correlates with non-condom
CSF in 85 patients with AIDS and CNS cryptococcosis.: Arq Neuropsiquiatr. 1992 Dec;50(4):491-6. Unique Identifier : AIDSLINE MED/93393457; Livramento JA; Machado LR; Nobrega JP; Gomes HR; Vianna LS; Spina-Franca A; CIN Neurology Investigation Center, Department of Neurology,; Faculty of Medicine, Sao Paulo University, Brasil.; In an eight years time period (July 1984-June 1992) CSF samples of 40718 patients were studied, and 610 were from patients with AIDS clinically diagnosed and immunologically confirmed through HIV antibodies detection. Among opportunistic infections detected in them 85 were CNS cryptococcosis. For the purpose of this s
Neurotoxoplasmosis and AIDS. Cerebrospinal fluid analysis in 96 patients.: Arq Neuropsiquiatr. 1992 Dec;50(4):497-500. Unique Identifier : AIDSLINE MED/93393458; Machado LR; Livramento JA; Spina-Franca A; CIN Neurology Investigation Center, Department of Neurology,; Faculty of Medicine, Sao Paulo University, Brasil.; The behavior of CSF inflammatory pattern in patients with AIDS and/or toxoplasmosis of the CNS is studied in 176 patients, divided in three groups. In the first group, 96 patients with toxoplasmosis and AIDS are considered; in the second group, 50 patients with toxoplasmosis without AIDS; in the third group, 30 AIDS p
An efficacy study of itraconazole in the treatment of Penicillium marneffei infection.: J Med Assoc Thai. 1992 Dec;75(12):688-91. Unique Identifier : AIDSLINE MED/93375278; Supparatpinyo K; Chiewchanvit S; Hirunsri P; Baosoung V; Uthammachai C; Chaimongkol B; Sirisanthana T; Department of Medicine, Faculty of Medicine, Chiang Mai; University, Thailand.; OBJECTIVES: to evaluate the efficacy and safety of itraconazole in treating P. marneffei infection. METHODS: Ten patients with previously untreated P. marneffei infection were given oral itraconazole at a dose of 200 mg twice a day for 2 months, followed by a dose of 100 mg once a day for 1 month. Efficacy was determi
Detection of cytomegalovirus in urine of HIV-infected patients by DNA-DNA hybridization comparison with virus isolation, immunofluorescence and immunoperoxidase.: Mem Inst Oswaldo Cruz. 1992 Jan-Mar;87(1):99-102. Unique Identifier : AIDSLINE MED/93375889; Valdivia A; Marrero M; Alvarez M; Mune M; Valdes O; Roges G; Instituto de Medicina Tropical Pedro Kouri, La Habana, Cuba.; Immunofluorescence and immunoperoxidase test directed against early viral antigens, and DNA-DNA hybridization were compared with viral isolation for their abilities to detect Cytomegalovirus ( CMV ) in the urine of 89 HIV infected patients. From the 100 urine samp
Molecular and biological diversity of HIV-1 in Brazil.: Mem Inst Oswaldo Cruz. 1992 Apr-Jun;87(2):249-55. Unique Identifier : AIDSLINE MED/93375901; Couto-Fernandez JC; Morgado MG; dos Santos JI; Galvao-Castro B; Laboratorio Avancado de Saude Publica, Centro de Pesquisas; Goncalo Moniz, Salvador, BA, Brasil.; To determine the genomic polymorphism and biological properties present in HIV-1 Brazilian isolates, we analyzed five viral isolates obtained from patients residing in Rio de Janeiro (P1 and P5), Sao Paulo (P3) and Bahia (P2 and P4) states. For each viral isolate in vitro characteristics such as replication rate, sync
Viruses, chemotherapy and immunity.: Parasitology. 1992;105 Suppl:S85-92. Unique Identifier : AIDSLINE MED/93390998; Koziel MJ; Walker BD; Infectious Disease Unit, Massachusetts General Hospital, Boston.; An increasing number of antiviral agents are presently in various stages of development and testing, and an increasing number have recently been licensed for use in humans. These drugs have been used extensively to treat viral infections in immunocompromised individuals, and these studies indicate that for many antivi
N-acetyl-cysteine is a potent suppressor of human immunodeficiency virus transcription in persistently infected cells.: Trans Assoc Am Physicians. 1992;105:36-43. Unique Identifier : AIDSLINE MED/93392314; Kinter AL; Poli G; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.
[HIV seropositivity in blood donors from 1990 to 1992: prevalence, estimation of residual risk of transfusion-related infections and epidemiology]: Rev Fr Transfus Hemobiol. 1993 Jul;36(4):327-37. Unique Identifier : AIDSLINE MED/93363121; Courouce AM; Institut National de Transfusion Sanguine, Paris.; In France , HIV seroprevalence in blood donations still decreased from 1990 to 1992 with an important diminution in 1992, in first time donors as well as in regular donors. During the last 1992 semester, this prevalence reached 0.051%: 0.19% and 0.026% in donations from first time a
The reliability and validity of two HIV-specific health-related Quality-of-Life measures: a preliminary analysis.: AIDS. 1993 Jul;7(7):1001-8. Unique Identifier : AIDSLINE MED/93363240; Burgess A; Dayer M; Catalan J; Hawkins D; Gazzard B; Department of Psychological Medicine, Chelsea and Westminster; Hospital, London, UK.; OBJECTIVE: To evaluate the reliability and validity of two HIV-specific Quality-of-Life (QoL) questionnaires in a UK sample. METHOD: Subjects were 99 HIV-seropositive gay men (23 were asymptomatic, 41 were asymptomatic, 35 had AIDS). QoL was measured using two HIV-specific QoL questionnaires. MEASURES: An adaptation o
Development of AIDS in people with transfusion-acquired HIV infection.: AIDS. 1993 Jul;7(7):1009-13. Unique Identifier : AIDSLINE MED/93363241; Kopec-Schrader E; Tindall B; Learmont J; Wylie B; Kaldor JM; National Centre in HIV Epidemiology and Clinical Research,; University of New South Wales, Sydney, Australia.; OBJECTIVE: To determine the rate of development of AIDS, and the demographic and clinical cofactors for development of AIDS in a group of 117 people with transfusion-acquired HIV infection, who were infected between 1980 and 1985 in New South Wales, Australia . RESULTS: By Decemb
Pneumocystis carinii choroidopathy in AIDS patients [letter]: AIDS. 1993 Jul;7(7):1015-6. Unique Identifier : AIDSLINE MED/93363242; Patey O; Salvanet A; Serrhini A; Lafaix C
Liposomal amphotericin B for leishmaniasis treatment of AIDS patients unresponsive to antimonium compounds [letter]: AIDS. 1993 Jul;7(7):1018-9. Unique Identifier : AIDSLINE MED/93363245; Lazanas MC; Tsekes GA; Papandreou S; Harhalakis N; Scandali A; Nikiforakis E; Saroglou G
Pyomyositis in patients with HIV infection [letter]: AIDS. 1993 Jul;7(7):1020-1. Unique Identifier : AIDSLINE MED/93363246; Soriano V; Laguna F; Diaz F; Polo R; Moreno V; Cobo J; Gonzalez-Lahoz J
High triglyceride levels as a predictor of mortality in AIDS patients [letter] [see comments]: AIDS. 1993 Jul;7(7):1022-3. Unique Identifier : AIDSLINE MED/93363247; Gonzalez-Clemente JM; Miro JM; Navarro MP; Zamora L; Vilardell E
Vertical transmission of hepatitis C virus and HIV [letter]: AIDS. 1993 Jul;7(7):1024-5. Unique Identifier : AIDSLINE MED/93363249; Maccabruni A; Caselli D; Mondelli M; Degioanni M; Cerino A
Comparison of eight commercial test kits for detecting anti-HIV antibodies in saliva specimens [letter]: AIDS. 1993 Jul;7(7):1026. Unique Identifier : AIDSLINE MED/93363251; Chamnanput J; Phanuphak P
HIV DNA and antibodies in syringes from injecting drug users: a comparison of detection techniques.: AIDS. 1993 Jul;7(7):925-31. Unique Identifier : AIDSLINE MED/93363255; Myers SS; Heimer R; Liu D; Henrard D; Department of Internal Medicine, Yale University School of; Medicine, New Haven, CT 06510.; OBJECTIVE: Direct HIV testing of individual injecting drug users is not always feasible. As an alternative, we have evaluated the sensitivity and specificity of several techniques for detecting HIV-1-specific products in used syringes. DESIGN: Polymerase chain reaction (PCR) and antibody-capture assays were compared u
A dose escalation study to determine the toxicity and maximally tolerated dose of foscarnet.: AIDS. 1993 Jul;7(7):941-5. Unique Identifier : AIDSLINE MED/93363257; Seidel EA; Koenig S; Polis MA; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892.; OBJECTIVE: To determine the maximum tolerated dose of intravenous foscarnet (trisodium phosphonoformate hexahydrate); and to examine antiviral activity at plasma levels shown to inhibit HIV-1. DESIGN: Dose escalation study in three male subjects with AIDS who received foscarnet by continuous intravenous infusion at a
Longitudinal study on the Quality of Life of symptomatic HIV-infected patients in a trial of zidovudine versus zidovudine and interferon-alpha.: AIDS. 1993 Jul;7(7):947-53. Unique Identifier : AIDSLINE MED/93363258; de Boer JB; van Dam FS; Sprangers MA; Frissen PH; Lange JM; WHO Collaborating Centre on Quality of Life, The Netherlands; Cancer Institute, Amsterdam.; OBJECTIVES: To compare the effect of treatment with zidovudine (ZDV) or a combination of ZDV and interferon-alpha (IFN-alpha) on patient Quality-of-Life (QoL); and to document changes over time in QoL. DESIGN: This study is part of a longitudinal, randomized, controlled clinical trial comparing the efficacy and tolera
The impact of HIV on infectiousness of pulmonary tuberculosis: a community study in Zambia.: AIDS. 1993 Jul;7(7):981-7. Unique Identifier : AIDSLINE MED/93363263; Elliott AM; Hayes RJ; Halwiindi B; Luo N; Tembo G; Pobee JO; Nunn PP; McAdam KP; School of Medicine, University of Zambia, Lusaka.; OBJECTIVE: To examine the impact of HIV on infectiousness of pulmonary tuberculosis (TB). DESIGN: A cross-sectional tuberculin survey carried out among household contacts of HIV-1-positive and negative patients with bacteriologically confirmed pulmonary TB. Contacts were also examined for active TB. SETTING: Index cas
A prospective study of vertical transmission of HIV-2 in Bissau, Guinea-Bissau.: AIDS. 1993 Jul;7(7):989-93. Unique Identifier : AIDSLINE MED/93363264; Andreasson PA; Dias F; Naucler A; Andersson S; Biberfeld G; Laboratorio Nacional de Saude Publica, Bissau, Guinea-Bissau.; OBJECTIVES: To determine the vertical transmission rate of HIV-2 and clinical findings associated with vertically transmitted HIV-2 infection. DESIGN: A prospective study of HIV-2 transmission in children of HIV-2-seropositive mothers, and a comparison of clinical findings between children of seropositive and seronega
Blood transfusion practices and blood-banking services in a Kenyan hospital.: AIDS. 1993 Jul;7(7):995-9. Unique Identifier : AIDSLINE MED/93363265; Lackritz EM; Ruebush TK 2d; Zucker JR; Adungosi JE; Were JB; Campbell CC; Division of Parasitic Diseases, Centers for Disease Control and; Prevention, Atlanta, GA 30341-3724.; OBJECTIVES: To identify ways to improve the operation of blood-screening programs and to decrease the inappropriate use of blood by evaluating blood-transfusion practices and blood-banking services in a Kenyan hospital. DESIGN: Prospective cohort. SETTING: The study was conducted in a rural district hospital in wester
'Revised guidelines for HIV-infected health care workers' [letter]: Br Dent J. 1993 Aug 7;175(3):91-2. Unique Identifier : AIDSLINE MED/93363406; Emery C
Panorama: a retrospect [see comments]: Br Dent J. 1993 Aug 21;175(4):119. Unique Identifier : AIDSLINE MED/93363411; Watson M; Practitioner Service, British Dental Association.
Bacterial arthritis.: Curr Opin Rheumatol. 1993 Jul;5(4):449-53. Unique Identifier : AIDSLINE MED/93363506; Ho G Jr; Division of Rheumatology, Miriam Hospital, Providence, RI 02906.; The 1992 literature on septic arthritis reiterated the factors that portend a poor outcome in septic arthritis. However, we still know very little about how to improve the outcome for such patients. Infections of the musculoskeletal system may be more common among patients with HIV than the reported cases indicate. Ba
Reactive arthropathy and autoimmunity in non-HIV-associated immunodeficiency.: Curr Opin Rheumatol. 1993 Jul;5(4):475-82. Unique Identifier : AIDSLINE MED/93363510; Iyer M; Gorevic PD; Department of Medicine, SUNY, Stony Brook 11794-8161.; The spectrum of arthropathy in non-HIV immune deficiency states includes arthritis due to prevalent infectious pathogens and autoimmunity that may in some instances be triggered by microorganisms. Joint symptoms may be clinical manifestations of disease, or they may develop later during therapy for immunodeficiency. P
Children have a right to AIDS facts [news]: Nurs Stand. 1993 Jul 14-20;7(43):11. Unique Identifier : AIDSLINE MED/93363528
HIV health education needs reassessing [news]: Nurs Stand. 1993 Jul 14-20;7(43):17. Unique Identifier : AIDSLINE MED/93363529
Structural and functional studies in vitro on the p6 protein from the HIV-1 gag open reading frame.: Biochim Biophys Acta. 1993 Sep 8;1182(2):157-61. Unique Identifier : AIDSLINE MED/93363652; Stys D; Blaha I; Strop P; Institute of Organic Chemistry and Biochemistry, Czech Academy of; Science, Prague.; Protein p6 from HIV-1 gag open reading frame is reported to affect both the final phase of assembly of the viral particle and the early stage of the gag polyprotein maturation in vitro. Two separate hypotheses have been proposed, on only one of these reported effects. We think that both observations may be eventually
Factors associated with heroin users' AIDS risk-taking behaviours.: Aust J Public Health. 1993 Mar;17(1):13-7. Unique Identifier : AIDSLINE MED/93363706; Caplehorn JR; Saunders JB; Centre for Drug and Alcohol Studies, Royal Prince Alfred; Hospital, Sydney.; A survey was undertaken in Sydney in 1989 to identify factors associated with behaviour involving risk for human immunodeficiency virus infection. Self-report data on needle-sharing and sexual practices were collected from 91 heroin users entering a residential, drug-free detoxification unit. Data were analysed using
Testing for HIV infection among heterosexual, bisexual and gay men [see comments]: Aust J Public Health. 1993 Mar;17(1):27-31. Unique Identifier : AIDSLINE MED/93363710; Waddell C; Department of Anthropology, University of Western Australia,; Nedlands.; This paper answers the questions: who is and is not tested for human immunodeficiency virus (HIV) antibodies, why, where are they tested, and what do they find difficult about the testing process? The data came from two samples of sexually active heterosexual, bisexual and gay men in Perth (N = 545). Bisexual and gay
Sexual practices, sexually transmitted diseases and other risk factors for HIV among injecting drug users.: Aust J Public Health. 1993 Mar;17(1):32-5. Unique Identifier : AIDSLINE MED/93363711; Chetwynd J; Chambers A; Hughes A; Department of Community Health and General Practice, Christchurch; School of Medicine, New Zealand.; Data were collected from 814 clients attending anonymously for counselling before tests for human immunodeficiency virus (HIV) infection at the Burnett Clinic in Auckland. Just over 10 per cent of clients (n = 83) reported ever having injected drugs. This group was matched according to age, gender, ethnicity and sexua
Structural engineering of the HIV-1 protease molecule with a beta-turn mimic of fixed geometry.: Protein Sci. 1993 Jul;2(7):1085-91. Unique Identifier : AIDSLINE MED/93364260; Baca M; Alewood PF; Kent SB; Scripps Research Institute, La Jolla, California 92037.; An important goal in the de novo design of enzymes is the control of molecular geometry. To this end, an analog of the protease from human immunodeficiency virus 1 (HIV-1 protease) was prepared by total chemical synthesis, containing a constrained, nonpeptidic type II beta-turn mimic of predetermined three-dimensiona
Lignified materials as medicinal resources. VI. Anti-HIV activity of dehydrogenation polymer of p-coumaric acid, a synthetic lignin, in a quasi-in-vivo assay system as an intermediary step to clinical trials.: Biol Pharm Bull. 1993 Apr;16(4):434-6. Unique Identifier : AIDSLINE MED/93364380; Shimizu N; Naoe T; Kawazoe Y; Sakagami H; Nakashima H; Murakami T; Yamamoto N; Faculty of Pharmaceutical Sciences, Nagoya City University,; Japan.; After the dehydrogenation polymer of p-coumaric acid, a synthetic lignin, was intravenously injected into mice, the serum was collected immediately, 15 min, 1 h, 5 h, and 24 h after the injection. The serum thus obtained was added to the assay medium containing MT-4 cells infected with HTLV-IIIB (an HIV-1 strain). Inh
[Sperm and HIV]: Contracept Fertil Sex. 1993 Jul-Aug;21(7-8):581-6. Unique Identifier : AIDSLINE MED/93364439; Mailloux G; Bournique B; Fondation de recherche en Hormonologie, Banque de sperme et; laboratoire de biologie moleculaire, Paris.; Screening and prevention are two major weapons in the fight against AIDS. Procreation of couples where the spouse is seropositive poses a serious ethical social and epidemiological problem. We have consequently established a list of the current biological data concerning HIV in the sperm at the level of non germinal c
On-the-job exposure to HIV: reducing RNs' risk (continuing education credit).: Calif Nurse. 1993 Jul-Aug;89(7):8-10. Unique Identifier : AIDSLINE MED/93364815; Carr G
Lack of risk of HIV transmission [letter]: J Can Dent Assoc. 1993 Aug;59(8):644. Unique Identifier : AIDSLINE MED/93364818; Epstein J
The questionable relationship between HIV and AIDS.: J Can Dent Assoc. 1993 Aug;59(8):693-5. Unique Identifier : AIDSLINE MED/93364824; Hardie J; Department of Dentistry, Vancouver General Hospital.
Calgary's needle exchange program: profile of injection drug users.: Can J Public Health. 1993 May-Jun;84(3):177-80. Unique Identifier : AIDSLINE MED/93364853; Elnitsky SL; Abernathy TJ; Department of Public Health, ON.; This report provides a baseline description of a sample of injection drug users who are clients of a needle exchange program in Calgary, Alberta. The results of the study suggest a relatively older, predominantly male clientele who reported heavy and sustained use of drugs, particularly cocaine. Despite a high level o
[Utilization of qualitative and quantitative methods to study the attitudes and beliefs related to AIDS in a Montreal population of Haitian origin]: Can J Public Health. 1993 May-Jun;84(3):186-91. Unique Identifier : AIDSLINE MED/93364856; Adrien A; Boivin JF; Hankins C; Leaune V; Tousignant Y; Tremblay J; Departement de sante communautaire de l'Hopital general de; Montreal, Quebec, Canada.; To determine attitudes and beliefs related to AIDS among the population of metropolitan Montreal of Haitian origin, we conducted serial cross-sectional surveys between 1987 and 1990 among a random sample of 777 men and women aged 15 to 39. Data on perceived risk of AIDS and attitudes towards HIV testing were collected
The Mycobacterium avium complex.: Clin Microbiol Rev. 1993 Jul;6(3):266-310. Unique Identifier : AIDSLINE MED/93364869; Inderlied CB; Kemper CA; Bermudez LE; Department of Pathology and Laboratory Medicine, Childrens; Hospital, Los Angeles, California 90027.; Mycobacterium avium complex (MAC) disease emerged early in the epidemic of AIDS as one of the common opportunistic infections afflicting human immunodeficiency virus-infected patients. However, only over the past few years has a consensus developed about its significance to the morbidity and mortality of AIDS. M. aviu
Immunopathogenesis of HIV-1-associated cardiomyopathy.: Clin Immunol Immunopathol. 1993 Aug;68(2):234-41. Unique Identifier : AIDSLINE MED/93365083; Herskowitz A; Willoughby S; Wu TC; Beschorner WE; Neumann DA; Rose NR; Baughman KL; Ansari AA; Department of Medicine, School of Public Health and Hygiene,; Johns Hopkins University, Baltimore, Maryland 21205.
Discrimination: individual rights vs. mandated behavior.: Bull Eighth Dist Dent Soc. 1993 Jan-Feb;27(1):8, 11. Unique Identifier : AIDSLINE MED/93365415; Cronyn B
Pulmonary toxoplasmosis in immunocompromised patients [letter; comment]: Eur J Clin Microbiol Infect Dis. 1993 Jun;12(6):475-6. Unique Identifier : AIDSLINE MED/93365469; Derouin F; Garin YJ
Absorption of zidovudine in patients with diarrhoea.: Eur J Clin Pharmacol. 1993;44(5):501-3. Unique Identifier : AIDSLINE MED/93365490; Zorza G; Beaugerie L; Taburet AM; Le Quintrec Y; Singlas E; Department of Clinical Pharmacy, Bicetre Hospital, Paris, France.; Many patients with AIDS have gastrointestinal complaints, including the major clinical disorder of chronic diarrhoea. The pharmacokinetics of zidovudine was studied in 9 male patients with HIV infection and diarrhoea to establish whether drug absorption was impaired in them. The peak plasma concentration and AUC after
In vitro testing of a glyoxalase I inhibitor.: Biochem Soc Trans. 1993 May;21(2):157S. Unique Identifier : AIDSLINE MED/93365805; Barnard JF; Vander Jagt DL; Honek JF; Department of Chemistry, University of Waterloo, Ontario, Canada.
Potential indications for octreotide in gastroenterology: summary of workshop.: Digestion. 1993;54 Suppl 1:59-67. Unique Identifier : AIDSLINE MED/93365999; Burroughs AK; Malagelada R; Hepatobiliary and Liver Transplantation Unit, Royal Free Hospital; and School of Medicine, London, UK.; The potential therapeutic applications of somatostatin and octreotide in gastroenterology involve gut neuro-endocrine tumours, bleeding varices, bleeding peptic ulcers, gastro-intestinal fistulae, pancreatic fistulae, dumping syndrome, pancreatic pseudocysts, short bowel syndrome, acute pancreatitis, AIDS-related diar
Anal dysplasia in homosexual men: role of anoscopy and biopsy.: Gastroenterology. 1993 Sep;105(3):658-66. Unique Identifier : AIDSLINE MED/93366109; Surawicz CM; Kirby P; Critchlow C; Sayer J; Dunphy C; Kiviat N; Department of Medicine, University of Washington School of; Medicine, Seattle.; BACKGROUND: Both anal squamous cell cancer and human papilloma virus (HPV) are increased in homosexual men. This study evaluates histology of internal anal abnormalities in a high-risk population of human immunodeficiency virus (HIV) seropositive and seronegative homosexual men. METHODS: Ninety men with abnormalities
[Worldwide foundation for AIDS research and prevention is organized (news)]: Fortschr Med. 1993 Jun 30;111(18):12. Unique Identifier : AIDSLINE MED/93366270
Potential use of mass media to reach urban intravenous drug users with AIDS prevention messages.: Int J Addict. 1993 Jul;28(9):837-51. Unique Identifier : AIDSLINE MED/93366487; Jason J; Solomon L; Celentano DD; Vlahov D; Centers for Disease Control (CDC), Department of Health and Human; Services, Atlanta, Georgia 30333.; To access the potential of using the mass media to reach urban intravenous drug users (IVDUs) with AIDS prevention messages, we: 1) questioned 353 participants in a Baltimore IVDU cohort study on their media use and sources of AIDS information, 2) analyzed data on Baltimore AIDS public service announcement (PSA) airin
Incidence of HIV-1 infection among adults in the Kagera region of Tanzania.: Int J Epidemiol. 1993 Jun;22(3):528-36. Unique Identifier : AIDSLINE MED/93366514; Killewo JZ; Sandstrom A; Bredberg Raden U; Mhalu FS; Biberfeld G; Wall S; Muhimbili Medical Centre, Dar es Salaam, Tanzania.; The results of a population-based follow-up study are presented. The baseline study which started in August 1987, was carried out to determine the prevalence of human immunodeficiency virus (HIV-1) infection in the Kagera region of Tanzania . A multistage cluster sampling techniqu
Determinants of HIV-1 infection in intravenous drug users in Valencia, Spain, 1987-1991.: Int J Epidemiol. 1993 Jun;22(3):537-42. Unique Identifier : AIDSLINE MED/93366515; Hernandez-Aguado I; Bolumar F; Instituto Valenciano de Estudios en Salud Publica, Universidad; de Alicante, Valencia, Spain.; From 1987 through 1991, 2687 intravenous drug users recruited at three AIDS information centres in the Region of Valencia ( Spain ) were interviewed about drug use and sexual behaviour and subsequently tested for HIV-1 antibody. The overall seroprevalence was high, 50% (95% confidence
HIV and AIDS indexed by MEDLINE [letter]: Int J Epidemiol. 1993 Jun;22(3):566. Unique Identifier : AIDSLINE MED/93366519; Elford J; Bor R; Summers P
Psychosocial factors and recurrent genital herpes: a review of prediction and psychiatric treatment studies.: Int J Psychiatry Med. 1993;23(2):99-117. Unique Identifier : AIDSLINE MED/93366556; Longo D; Koehn K; Geisinger Medical Center, Danville, Pennsylvania.; OBJECTIVE: The purpose of this review was to evaluate the evidence which supports the association between psychosocial factors and genital herpes simplex virus recurrences (HSV), as well as to examine the biological and psychological treatments for disease. METHOD: Forty-five st
Nosocomial tuberculosis in the AIDS era with an emphasis on multidrug-resistant disease.: Heart Lung. 1993 Jul-Aug;22(4):365-9. Unique Identifier : AIDSLINE MED/93366637; Snider DE Jr; Dooley SW; National Center for Prevention Services, Centers for Disease; Control, Atlanta, GA 30333.
Detection of human T-cell lymphotropic virus type 1 infection by the polymerase chain reaction using dried blood specimens on filter papers.: J Virol Methods. 1993 Jun;43(1):111-22. Unique Identifier : AIDSLINE MED/93366997; Noda S; Eizuru Y; Minamishima Y; Ikenoue T; Mori N; Department of Microbiology, Miyazaki Medical College, Japan.; A simple method for detection of proviral DNA sequences of human T-cell lymphotropic virus type 1 (HTLV-1) was developed using dried blood specimens on filter papers. The whole blood was blotted onto the Guthrie paper. After the blood has dried, the blotted paper was punched out into small discs. The discs were then b
Eosinophilia in early-stage human immunodeficiency virus infection.: J Allergy Clin Immunol. 1993 Sep;92(3):494-5. Unique Identifier : AIDSLINE MED/93367122; Sanchez-Borges M; Orozco A; Di Biagio E; Tami I; Suarez-Chacon R; Centro de Oncologia y Hematologia, Ministerio de Sanidad y; Asistencia Social, Caracas, Venezuela.
New AIDS research institute opens in San Francisco [news]: Infect Control Hosp Epidemiol. 1993 Jun;14(6):351. Unique Identifier : AIDSLINE MED/93367192
NIH opens first trial of HIV vaccines in children [news]: Infect Control Hosp Epidemiol. 1993 Jun;14(6):352. Unique Identifier : AIDSLINE MED/93367193
Court rules on patient's right to file suit for fear of contracting HIV from surgeon [news]: Infect Control Hosp Epidemiol. 1993 Jun;14(6):352-3. Unique Identifier : AIDSLINE MED/93367194
Response of hemophilic patients to poliovirus vaccination: correlation with HIV serology and with immunological parameters.: J Med Virol. 1993 Jun;40(2):91-5. Unique Identifier : AIDSLINE MED/93367422; Varon D; Handsher R; Dardik R; Gitel S; Ra'anani P; Heim M; Martinowitz U; National Hemophilia Center, Sheba Medical Center, Tel-Hashomer,; Israel.; Hemophilic patients may present immunological dysfunctions resulting from either human immunodeficiency virus (HIV) infection, or other factors like impure factor VIII concentrate and other viral infections. We evaluated prospectively the serologic response to polio vaccination of Israeli hemophilic patients who were
Lithium neurotoxicity at therapeutic levels in an AIDS patient.: J Nerv Ment Dis. 1993 Aug;181(8):518-9. Unique Identifier : AIDSLINE MED/93367432; Tanquary J; SUNY College of Medicine, Syracuse.
A brain bank in a neuropathology laboratory (with some emphasis on diagnostic criteria).: J Neural Transm Suppl. 1993;39:107-18. Unique Identifier : AIDSLINE MED/93367438; Duyckaerts C; Sazdovitch V; Seilhean D; Delaere P; Hauw JJ; Laboratoire de Neuropathologie R. Escourolle, INSERM U360,; Hopital de La Salpetriere, Paris, France.; The Brain Bank of La Salpetriere Hospital (Paris) is implanted in a neuropathology laboratory. It is multipurpose, prospective, and free of charge for the users. Protocols are prospectively established, in collaboration with the neuroscientists. One of our major difficulties in the collection of cases concerns present
Human neuro-specimen banking 1961-1992. The National Neurological Research Specimen Bank (a donor program of pre- and post-mortem tissues and cerebrospinal fluid/blood; and a collection of cryopreserved human neurological specimens for neuroscientists).: J Neural Transm Suppl. 1993;39:5-15. Unique Identifier : AIDSLINE MED/93367455; Tourtellotte WW; Rosario IP; Conrad A; Syndulko K; Neurology Service, VAMC W. Los Angeles, CA.; The National Neurological Research Specimen Bank (The Bank) was established in 1961 to provide a vital service to neuroscientists. Our purpose is to support medical research which seeks the etiopathogenesis for devastating neurological disorders with no known cause, treatment or precise animal model. It serves as a br
The contemporary AIDS database and brain bank--lessons from the past.: J Neural Transm Suppl. 1993;39:77-85. Unique Identifier : AIDSLINE MED/93367457; Davies J; Everall IP; Lantos PL; Department of Neuropathology, Institute of Psychiatry, London,; U.K.; This paper addresses the issues in establishing a contemporary AIDS Brain Bank with a Database. It draws comparisons from the past when a similar approach was made towards the understanding of mental illness and its treatment. The aim of the Brain Bank is to provide a comprehensive range of neuropathologically charact
Spinal epidural leiomyoma occurring in an HIV-infected man. Case report.: J Neurosurg. 1993 Sep;79(3):442-5. Unique Identifier : AIDSLINE MED/93367604; Steel TR; Pell MF; Turner JJ; Lim GH; Department of Neurosurgery, St. Vincent's Hospital, Sydney,; Australia.; A case of spinal epidural leiomyoma is reported in a 52-year-old man infected with the human immunodeficiency virus (HIV). The tumor arose in the epidural region at the T-3 vertebral level, and the patient presented with radicular pain in the right T-3 dermatome. While soft-tissue tumors such as Kaposi s sarcoma and l
Unique AIDS treatment facility.: J Nurs Adm. 1993 Jul-Aug;23(7-8):40, 45. Unique Identifier : AIDSLINE MED/93367625; Stapler EJ; Brooklyn VA Medical Center, New York.
Alpha-keto and alpha-hydroxy branched-chain acid interrelationships in normal humans.: J Nutr. 1993 Sep;123(9):1513-21. Unique Identifier : AIDSLINE MED/93367639; Hoffer LJ; Taveroff A; Robitaille L; Mamer OA; Reimer ML; McGill Nutrition and Food Science Centre, Royal Victoria; Hospital, Montreal, Quebec, Canada.; Plasma concentrations of the branched-chain amino acids leucine, isoleucine and valine, and those of leucine s and isoleucine s transamination products alpha-ketoisocaproic acid (KICA) and alpha-keto-beta-methylvaleric acid (KMVA), respectively, are known to increase after a protein meal or during extended fasting, bu
Potent HIV protease inhibitors: the development of tetrahydrofuranylglycines as novel P2-ligands and pyrazine amides as P3-ligands.: J Med Chem. 1993 Aug 6;36(16):2300-10. Unique Identifier : AIDSLINE MED/93367769; Ghosh AK; Thompson WJ; Holloway MK; McKee SP; Duong TT; Lee HY; Munson PM; Smith AM; Wai JM; Darke PL; et al; Department of Medicinal Chemistry, Merck Research Laboratory,; West Point, Pennsylvania 19486.; A series of protease inhibitors bearing constrained unnatural amino acids at the P2-position and novel heterocycles at the P3-position of compound 1 (Ro 31-8959) were synthesized, and their in vitro enzyme inhibitory and antiviral activities were evaluated. Replacem
A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of gamma-turn mimetics into a model substrate.: J Med Chem. 1993 Aug 6;36(16):2321-31. Unique Identifier : AIDSLINE MED/93367771; Newlander KA; Callahan JF; Moore ML; Tomaszek TA Jr; Huffman WF; Department of Medicinal Chemistry, Peptidomimetic Research,; SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania; 19406.; C7 mimetics, designed to lock three amino acid residues of a peptide chain into a gamma-turn conformation, were introduced sequentially between the P3 to P2 positions of a model HIV-1 protease substrate I (resulting in compounds II-IV) to probe its conformational requirements in binding to HIV-1 protease. Of these, c
[Usefulness of BAL in understanding of pulmonary diseases]: Rinsho Byori. 1993 Feb;41(2):189-96. Unique Identifier : AIDSLINE MED/93367954; Ina Y; 2nd Department of Internal Medicine, Nagoya City University.; Since the introduction of bronchoalveolar lavage (BAL) by Reynolds, et al. in 1974, direct examination of cells from interest sites in the lung has generated great progress in our understanding of pulmonary diseases. In the present study, BAL and the clinical usefulness of BAL in diagnosing and treating pulmonary dise
1992 Stohlman Memorial Lecture: targeting the IL-2 receptor.: Leukemia. 1993 Aug;7 Suppl 2:S151-6. Unique Identifier : AIDSLINE MED/93368196; Waldmann TA; Metabolism Branch, National Cancer Institute, National Institutes; of Health, Bethesda, MD 20892.; Patients with human T-cell lymphotropic virus I (HTLV-I)-associated leukemia/lymphoma were treated with different forms of IL-2 receptor (IL-2R)-directed therapy that exploit the difference in IL-2R expression between normal and malignant cells. Using unmodified anti-T
Studies of HIV-2 promoter activity and cell specific ablation.: Leukemia. 1993 Aug;7 Suppl 2:S61-5. Unique Identifier : AIDSLINE MED/93368211; Brady HJ; Miles CG; Pennington DJ; Dzierzak EA; Laboratory of Gene Structure and Expression, National Institute; for Medical Research, Mill Hill, London, U.K.; We have a developed a retroviral mediated molecular ablation method to specifically eliminate HIV Tat-expressing cells. This approach utilizes the Tat-inducible HIV-2 promoter and a conditional toxin gene. The Herpes Simplex Virus thymidine kinase gene product is toxic to mammalian cells only after treatment with Ganc
Natural history of HTLV-I infection: relationship to leukemogenesis.: Leukemia. 1993 Aug;7 Suppl 2:S75-7. Unique Identifier : AIDSLINE MED/93368214; Manns A; Viral Epidemiology Branch, National Cancer Institute, Bethesda,; MD.
Vaccinia virus vectors for study of membrane fusion mediated by human immunodeficiency virus envelope glycoprotein and CD4.: Methods Enzymol. 1993;221:12-8. Unique Identifier : AIDSLINE MED/93368440; Ashorn P; Berger EA; Moss B; Department of Biochemical Sciences, University of Tampere,; Finland.
Fusion of human immunodeficiency virus-infected cells with uninfected cells.: Methods Enzymol. 1993;221:3-12. Unique Identifier : AIDSLINE MED/93368455; Lifson JD; Division of Cellular Immunology, Genelabs Incorporated, Redwood; City, California 94063.; CD4-dependent HIV envelope glycoprotein-induced membrane fusion events play a key role in the life cycle of HIV and are involved both in infection mediated by viral particles and in virally mediated cytopathic processes. The relevant events involve binding interactions between the HIV envelope glycoprotein gp120 and t
Protein conformational changes in virus-cell fusion.: Methods Enzymol. 1993;221:61-72. Unique Identifier : AIDSLINE MED/93368464; Doms RW
Prevention of HIV and HBV transmission in general practice [see comments]: Med J Aust. 1993 Sep 6;159(5):339-42. Unique Identifier : AIDSLINE MED/93368518; Cooper CW; Department of General Practice, University of Sydney, Croydon,; NSW.
Frequency of bleeding in football [letter]: Med J Aust. 1993 Sep 6;159(5):353. Unique Identifier : AIDSLINE MED/93368522; Seward HG; Orchard JW; Hazard H; Collinson DC
Dry mouth in HIV infection [letter]: Med J Aust. 1993 Sep 6;159(5):355. Unique Identifier : AIDSLINE MED/93368526; Foltyn P
Addison's disease in the acquired immunodeficiency syndrome [letter] [see comments]: Med J Aust. 1993 Sep 6;159(5):359-60. Unique Identifier : AIDSLINE MED/93368537; Birchall D; Comty C
[Immunoreactivity of synthetic peptides, corresponding to B-cellular epitopes of human type I T-lymphotrophic virus structural proteins]: Mol Biol (Mosk). 1993 Jul-Aug;27(4):880-7. Unique Identifier : AIDSLINE MED/93368590; Rasuli AM; Klepikov NN; Andreev SM; Sidorova MV; Vafina MG; Seniuta NB; Pavlish OA; Syrtsev AV; Gurtsevich VE; The immunoreactivity of 25 synthetic peptides corresponding to amino acid fragments of the HTLV-I structural proteins p19 gag, gp46 and gp21 env were studied in enzyme linked immunosorbent assay using a serum panel of 70 reference positive specimens with anti-HTLV-I antibodies. The location of the synthetic peptides c
[Model of the spatial structure of peptide T]: Mol Biol (Mosk). 1993 Jul-Aug;27(4):934-46. Unique Identifier : AIDSLINE MED/93368596; Andrianov AM; Akhrem AA; The spatial structure model of peptide T (AIDS reproduction inhibitor, the amino acid sequence of which corresponds to the fragment into the binding site of the virus protein gp120 with T4 receptor) is proposed. Peptide structure modelling has been carried out by the previously developed method based on joint usage of
[Vascular complications in drug addicts. Intermittent claudication in a HIV seropositive heroin addict]: Minerva Cardioangiol. 1993 Jun;41(6):265-8. Unique Identifier : AIDSLINE MED/93368755; Boneschi M; Miani S; Erba M; Giuffrida GF; Eusebio D; Giordanengo F; Istituto di Chirurgia Generale e Cardiovascolare, Universita; degli Studi di Milano.; The widespread use of heroin has revealed the growing life-threatening complications consequent on drug practice. The effects of heroin on the cardiovascular, pulmonary, renal and central nervous system have been well described in medical literature, but the vascular complication of chronic occlusive arterial disease
AIDS update: caring for patients with diarrhea.: Nursing. 1993 Aug;23(8):68-70. Unique Identifier : AIDSLINE MED/93368876; Anastasi JK
[Azidothymidine in the management of immune deficiency complex]: Orv Hetil. 1993 Aug 29;134(35):1921-5. Unique Identifier : AIDSLINE MED/93368928; Balint Gabor S; Szent-Gyorgyi Albert Orvostudomanyi Egyetem Ideg- es; Elmegyogyaszati Klinikajanak Klinikai Farmakologiai; Laboratoriuma, Szeged.; The nucleoside-analogue azidothymidine is the first effective drug in the management of HIV-infection although it is not a causal therapy. Azidothymidine increases the life-span of the HIV-positive patients, decreases the incidence of opportunistic infections and enhances the quality of life. The current recommendatio
A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box.: Oncogene. 1993 Sep;8(9):2391-7. Unique Identifier : AIDSLINE MED/93368940; Suzuki T; Hirai H; Fujisawa J; Fujita T; Yoshida M; Department of Cellular and Molecular Biology, University of; Tokyo, Japan.; A transcriptional activator of human T-cell leukemia virus type 1 (HTLV-1) activates at least three distinct enhancers: the viral 21-bp enhancer, the NF-kappa B binding site of the IL-2R alpha gene and the CArG box of the c-fos gene. To understand the mechanisms of Tax transactivations of the NF-kappa B enhancer and C
The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in chicken embryo fibroblasts.: Oncogene. 1993 Sep;8(9):2501-9. Unique Identifier : AIDSLINE MED/93368953; Sif S; Capobianco AJ; Gilmore TD; Department of Biology, Boston University, Massachusetts 02215.; The v-Rel oncoprotein of the avian Rev-T retrovirus is a member of a family of related transcription factors, which also includes the subunits of NF-kappa B and several other interacting cellular proteins. We show here that v-Rel specifically increased expression from a reporter plasmid containing multiple Sp1 binding
Understanding of acquired immunodeficiency syndrome by elementary school children--a developmental survey.: Pediatrics. 1993 Sep;92(3):389-95. Unique Identifier : AIDSLINE MED/93369011; Schonfeld DJ; Johnson SR; Perrin EC; O'Hare LL; Cicchetti DV; Department of Pediatrics, Yale University School of Medicine, New; Haven, CT 06510.; OBJECTIVES. The developmental process by which young children acquire an understanding of the concepts of causality, treatment, and prevention of illness as related to acquired immunodeficiency syndrome (AIDS) is poorly understood. Previous studies have focused on adolescent populations and have measured the facts tha
Zidovudine pharmacokinetics in HIV-positive women during different phases of the menstrual cycle.: Pharmacotherapy. 1993 Jul-Aug;13(4):369-77. Unique Identifier : AIDSLINE MED/93369087; Cordaro JA; Morse GD; Bartos L; Gugino LJ; Maliszewski M; Colomaio R; Shelton M; O'Donnell A; Hewitt R; Center for Clinical Pharmacy Research, State University of New; York, Buffalo 14215.; STUDY OBJECTIVE. To examine the pharmacokinetics of zidovudine during the menstrual cycle in human immunodeficiency virus- (HIV-) positive women. DESIGN. Open, unblinded study. SETTING. A women s clinic for acquired immunodeficiency syndrome (AIDS) at a large medical center. PATIENTS. HIV-positive women with a CD4+ ce
[Pulmonary tuberculosis and HIV seropositivity at the Principal Hospital of Dakar (Senegal)]: Rev Med Interne. 1993 Jan;14(1):14-20. Unique Identifier : AIDSLINE MED/93369382; Brucker-Davis F; Le Guenno B; Bah A; Griffet P; Launois P; Institut Pasteur, Dakar, Senegal.; In a prospective survey conducted in 1990 in the Principal Hospital of Dakar, pulmonary tuberculosis was 2.3 times more frequent in HIV seropositive patients (12.5%) than in HIV seronegative patients. We studied 22 cases of pulmonary tuberculosis in HIV+ patients and compared them with a control group of HIV- patients
[Consequences of specific prevention on the diagnosis of Pneumocystis carinii pneumonia in patients with HIV infection. Comite SIDA de l'Hopital Saint-Antoine]: Rev Med Interne. 1993 Jan;14(1):21-4. Unique Identifier : AIDSLINE MED/93369383; Chouaid C; Schuller MP; Febvre M; Urban T; Housset B; Lebeau B; Service de Pneumologie, Hopital Saint-Antoine, Paris.; In a prospective study the authors compared the clinical, radiological, biochemical and diagnostic features of Pneumocystis carinii pneumonia (PCP) in HIV-infected patients who were or were not receiving a specific prophylactic treatment. The study included 386 patients with suspected PCP, 201 of whom were under speci
[Cholangiopathies in AIDS (letter)]: Rev Med Interne. 1993 Jan;14(1):63-4. Unique Identifier : AIDSLINE MED/93369396; Heudier P; Taillan B; Fuzibet JG; Dujardin P
Final OSHA standard on occupational exposure to bloodborne pathogens.: Trends Tech Contemp Dent Lab. 1993 Mar;10(2):53-6. Unique Identifier : AIDSLINE MED/93369463; Railton WS; Alloy MP
Intestinal permeability and function in patients infected with human immunodeficiency virus. A comparison with coeliac disease.: Scand J Gastroenterol. 1993 Jul;28(7):573-80. Unique Identifier : AIDSLINE MED/93369523; Lim SG; Menzies IS; Lee CA; Johnson MA; Pounder RE; University Dept. of Medicine, Royal Free Hospital and School of; Medicine, London, U.K.; The relationships among intestinal permeability, advancing human immunodeficiency virus (HIV) infection, and the presence of diarrhoea or weight loss were investigated in 51 HIV patients and 20 healthy controls. Ten patients with untreated coeliac disease were also investigated for comparison. Fasting subjects drank a
HIV-antibody testings among injecting drug users (IDUs) in the Stockholm area, 1984-91: information compiled from testing laboratories.: Scand J Infect Dis. 1993;25(3):289-95. Unique Identifier : AIDSLINE MED/93369542; Bottiger M; Biberfeld G; Janzon R; Forsgren M; Von Sydow M; Grillner L; Annell A; Department of Epidemiology & Immunology, National Bacteriological; Laboratory, Stockholm, Sweden.; The available information about testings for HIV antibodies in injecting drug users (IDUs) carried out in Stockholm between 1984 and 1992 has been compiled. These testings were carried out mainly in special settings. The use of codes (the first 2 digits giving the age and the last 4 the 6 and checking figures in the i
Screening for anti-HIV and HBsAg in pooled sera from a clinical chemistry section as a tool for epidemiological survey.: Scand J Infect Dis. 1993;25(3):297-303. Unique Identifier : AIDSLINE MED/93369543; Hansson BG; Hansson HB; Ohlin AK; Nordenfelt E; Department of Medical Microbiology, General Hospital, Malmo,; Sweden.; With the aim of estimating the unknown spread of HIV into the general society, a program for testing pooled routine sera from a clinical chemistry laboratory has been tried. Serum samples obtained from the daily inflow of blood tubes at the Clinical Chemistry Laboratory, Malmo General Hospital, and not labelled as ris
The C-reactive protein responses in HIV-infected patients with pneumonia.: Scand J Infect Dis. 1993;25(3):305-9. Unique Identifier : AIDSLINE MED/93369544; Storgaard M; Laursen AL; Andersen PL; Department of Medicine and Infectious Diseases, Marselisborg; Hospital, University of Aarhus, Denmark.; The acute phase C-reactive protein (CRP) was measured in serum of HIV-infected patients suffering from Pneumocystis carinii pneumonia (PCP) (32 patients), bacterial pneumonia (10 patients), and in 19 immunocompetent patients with bacterial pneumonia. The HIV-infected patients with bacterial pneumonia had a significant
Pneumocystis carinii pneumonia presenting as an upper lobe cavity after aerosolized pentamidine prophylaxis in an HIV-infected patient.: Scand J Infect Dis. 1993;25(3):379-83. Unique Identifier : AIDSLINE MED/93369555; Ewig S; Rockstroh JK; Christ F; Department of Internal Medicine, Universitat Bonn, Germany.; We describe an atypical diagnostic feature of a breakthrough Pneumocystis carinii pneumonia (PCP) during primary prophylaxis with aerosolized pentamidine. Our case disclosed infiltrates restricted to the left upper lobe. After 2 weeks a solitary cavity developed. Diagnosis was easily established by bronchoalveolar lav
Absence of human T-lymphotropic retrovirus type-1 (HTLV-1) in different populations of Mongolia.: Scand J Infect Dis. 1993;25(3):398-9. Unique Identifier : AIDSLINE MED/93369559; Batsuuri J; Dashnyam B; Maidar J; Battulga D; Dorjsuren D; Ishida T; Department of Genetics, National Centre of Anthropology,; Mongolian State University of Medicine, Ulan-Bator.; The prevalence of human T-lymphotropic retrovirus type-1 (HTLV-1) was surveyed in Mongolia . A total of 1100 blood samples from different ethnic groups of the Mongolian population were examined for the presence of antibodies to HTLV-1 by serological tests using particle agglutinat
Problems in financing the care of AIDS patients.: Soc Work. 1993 Jul;38(4):369-77. Unique Identifier : AIDSLINE MED/93369665; Ozawa MN; Auslander WF; Slonim-Nevo V; George Warren Brown School of Social Work, Washington University,; St. Louis, MO 63130-4899.; The problem of financing the care of patients with acquired immune deficiency syndrome (AIDS) has reached crisis proportions. How will the United States cope with paying for the care of AIDS patients, many of whom either are denied private insurance or simply do not have money to pay f
A community-based approach to HIV case management: systematizing the unmanageable.: Soc Work. 1993 Jul;38(4):380-7. Unique Identifier : AIDSLINE MED/93369666; Indyk D; Belville R; Lachapelle S; Gordon G; Dewart T; Mount Sinai School of Medicine, New York, NY 10028.; This article presents an analysis and typology of community-based care for a young Hispanic mother with acquired immune deficiency syndrome (AIDS). It develops a conceptual framework that examines retrospectively the needs generated by AIDS over time, the appropriateness of the services, and an assessment of the inter
Testing the sexually abused child for the HIV antibody: issues for the social worker.: Soc Work. 1993 Jul;38(4):389-94. Unique Identifier : AIDSLINE MED/93369667; Gellert GA; Berkowitz CD; Gellert MJ; Durfee MJ; Arizona Department of Health Services, Phoenix 85012.; The frequency of HIV transmission to children and adolescents through sexual abuse is unknown. Because the incidences of HIV infection and of reported sexual abuse are both increasing, the transmission of HIV to children through sexual abuse may also be increasing. Social workers may have expanding roles in the decisi
Influence of education on self-perceived attitudes about HIV/AIDS among human services providers.: Soc Work. 1993 Jul;38(4):396-401. Unique Identifier : AIDSLINE MED/93369668; Riley JL; Greene RR; Health Science and Policy Program, University of Maryland,; Baltimore 21228.; Participants in a number of different HIV/AIDS educational programs, varying in content, length of course, and student audience, were surveyed to determine if education could help reduce fear and increase comfort in work with HIV/AIDS clients. It was hypothesized that attitude scores would improve following exposure t
Judgments of personal responsibility for HIV infection: an attributional analysis.: Soc Work. 1993 Jul;38(4):403-10. Unique Identifier : AIDSLINE MED/93369669; McDonell JR; School of Social Service, University of Tennessee, Chattanooga; 37304-2598.; This article examines the influence that attributions of personal responsibility for infection with the human immunodeficiency virus have on service and policy responses to the epidemic. A model of attributed responsibility is proposed that classifies social judgments of another person s behavior that take into accoun
AIDS and social work: the ethics and civil liberties agenda.: Soc Work. 1993 Jul;38(4):412-9. Unique Identifier : AIDSLINE MED/93369670; Reamer FG; School of Social Work, Rhode Island College, Providence 02908.; Social workers are becoming increasingly involved in casework and social policy debate related to the acquired immune deficiency syndrome (AIDS) crisis. To enhance their delivery of services and contribution to policy formulation, social workers need to be familiar with a wide range of ethical and civil liberties issu
Some characteristics of hospitalized HIV seropositive patients in Myanmar.: Southeast Asian J Trop Med Public Health. 1993 Mar;24(1):18-22. Unique Identifier : AIDSLINE MED/93369689; Soe S; Win PP; Zaw AK; Hla NN; Lwin S; Myint S; Swe T; Mya Y; Department of Medical Research, Yangon General Hospital, Myanmar.; Twenty-two hospitalized HIV seropositive patients were studied prospectively between July 1991 and January 1992. The majority of the patients were intravenous drug users (IVDUs). Their age ranged from 20 to 38 years with a male preponderance of 12 to 1. Anemia, lymphopenia and thrombocytopenia were observed in 100%, 3
Correlation between histopathologic features and magnetic resonance images of spinal cord lesions.: Spine. 1993 Jul;18(9):1140-9. Unique Identifier : AIDSLINE MED/93369716; Ohshio I; Hatayama A; Kaneda K; Takahara M; Nagashima K; Department of Orthopedic Surgery, Hokkaido University School of; Medicine, Sapporo, Japan.; The authors report a correlation between histopathologic features and magnetic resonance images of spinal cord lesions in 19 human spinal cords with various types of lesions. Abnormally high T2-weighted image signal intensities appeared nonspecifically in mildly altered lesions or areas with edema. In the gray matter,
AIDS education and training centers (AETCs) as resources [editorial]: Spec Care Dentist. 1993 Jan-Feb;13(1):5-6. Unique Identifier : AIDSLINE MED/93369748; Mulligan R; Department of Dental Medicine & Public Health, University of; Southern California, School of Dentistry.
Anti-HIV in Spanish blood donations from 1988 to 1991. Spanish Study Group on HIV blood donations screening [letter]: Vox Sang. 1993;65(1):71-2. Unique Identifier : AIDSLINE MED/93369965; De Andres-Medina R; Perez-Alvarez L; Najera-Morrondo R
[Thrombocytopenia associated with HIV infection]: Acta Haematol Pol. 1993;24(2 Suppl 1):33-9. Unique Identifier : AIDSLINE MED/93370103; Lopaciuk S; Samodzielnej Pracowni Krzepniecia Krwi i Hemostazy, Instytutu; Hematologii i Transfuzjologii, Warszawie.; Thrombocytopenia is a common complication of human immunodeficiency virus (HIV) infection. Its pathogenesis has not yet been established. An increased platelet destruction either due to the nonspecific deposition of circulating immune complexes on platelets or to the presence of specific antiplatelet antibodies as wel
AIDS update [news]: Am Fam Physician. 1993 Sep 1;48(3):528. Unique Identifier : AIDSLINE MED/93370208
Gastric toxoplasmosis in the acquired immunodeficiency syndrome [letter; comment]: Am J Gastroenterol. 1993 Sep;88(9):1464-5. Unique Identifier : AIDSLINE MED/93370382; Peraire J; Vidal F; Mayayo E; Razquin S; Richart C
Alterations of thymus cortical epithelium and interdigitating dendritic cells but no increase of thymocyte cell death in the early course of simian immunodeficiency virus infection.: Am J Pathol. 1993 Sep;143(3):699-713. Unique Identifier : AIDSLINE MED/93370550; Muller JG; Krenn V; Schindler C; Czub S; Stahl-Hennig C; Coulibaly C; Hunsmann G; Kneitz C; Kerkau T; Rethwilm A; et al; Institute of Pathology, University of Wurzburg, Germany.; The role of the thymus in the pathogenesis of simian acquired immunodeficiency syndrome was investigated in 18 juvenile rhesus monkeys (Macaca mulatta). The thymus was infected from the first week post-SIVmac inoculation, but the amount of virus-positive cells was very low (
Effects of human immunodeficiency virus sera and macrophage supernatants on mesangial cell proliferation and matrix synthesis.: Am J Pathol. 1993 Sep;143(3):814-22. Unique Identifier : AIDSLINE MED/93370560; Mattana J; Abramovici M; Singhal PC; Department of Medicine, Long Island Jewish Medical Center, New; Hyde Park, New York 11042.; Patients with human immunodeficiency virus (HIV) infection are prone to the development of focal segmental glomerulosclerosis, a lesion in which increased mesangial cell proliferation and matrix synthesis may play a role. We undertook the present study to determine whether HIV sera may affect mesangial cell proliferat
Drug users' self-reported false-positive HIV status [letter; comment]: Am J Public Health. 1993 Sep;83(9):1349-51. Unique Identifier : AIDSLINE MED/93370610; Ross MW; Loxley W; Wodak A; Buzolic A; Monheit B; Stowe A
Primary cutaneous tuberculosis after a needlestick injury from a patient with AIDS and undiagnosed tuberculosis.: Ann Intern Med. 1993 Oct 1;119(7 Pt 1):594-5. Unique Identifier : AIDSLINE MED/93370789; Kramer F; Sasse SA; Simms JC; Leedom JM; LAC/USC Medical Center, Section of Infectious Diseases 90033.
Effect of HIV infection on response to syphilis [letter; comment]: Ann Intern Med. 1993 Oct 1;119(7 Pt 1):635-6. Unique Identifier : AIDSLINE MED/93370803; el-Sadr W; Flam R
Immunomodulating drugs: major advances in research and development.: Ann N Y Acad Sci. 1993 Jun 23;685:1-10. Unique Identifier : AIDSLINE MED/93370836; St. Georgiev V; National Institute of Allergy and Infectious Diseases, National; Institutes of Health, Bethesda, Maryland 20892.
Immunomodulator effects on the Friend virus infection in genetically defined mice.: Ann N Y Acad Sci. 1993 Jun 23;685:432-46. Unique Identifier : AIDSLINE MED/93370886; Sidwell RW; Morrey JD; Okleberry KM; Burger RA; Warren RP; Institute for Antiviral Research, Utah State University, Logan; 84322-5600.; The disease induced by the Friend virus complex (FV) in F1 hybrid mice containing the Rfv-3r/s genotype in the presence of H-2a/a was used to evaluate a variety of immunomodulating substances. In these genetically defined mice, the FV disease results in splenomegaly, early production of high titers of cell-associated
Antiviral activity of a synthetic double-stranded polyribonucleotide interferon inducer in a murine AIDS retrovirus model. Role of augmentation of natural killer cell activity and synergy with oral AZT.: Ann N Y Acad Sci. 1993 Jun 23;685:467-70. Unique Identifier : AIDSLINE MED/93370891; Black PL; McKinnon KM; Wooden SL; Ussery MA; Division of Antiviral Drug Products, Food and Drug; Administration, Rockville, Maryland 20857.
The interleukin-2 receptor: a target for immunotherapy.: Ann N Y Acad Sci. 1993 Jun 23;685:603-10. Unique Identifier : AIDSLINE MED/93370909; Waldmann TA; Goldman C; Top L; Grant A; Burton J; Bamford R; Roessler E; Horak I; Zaknoen S; Kasten-Sportes C; et al; Metabolism Branch, National Cancer Institute, National Institutes; of Health, Bethesda, Maryland 20892.
Immunologic approaches to the therapy of HIV-1 infection.: Ann N Y Acad Sci. 1993 Jun 23;685:687-96. Unique Identifier : AIDSLINE MED/93370919; Sneller MC; Lane HC; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda,; Maryland 20892.
Gene transfer for therapy and prophylaxis of HIV-1 infection.: Ann N Y Acad Sci. 1993 Jun 23;685:697-712. Unique Identifier : AIDSLINE MED/93370920; Rohrbaugh ML; McGowan JJ; Division of Extramural Activities, National Institute of Allergy; and Infectious Diseases, National Institutes of Health, Bethesda,; Maryland 20892.
Superantigens in infectious diseases, including AIDS.: Ann N Y Acad Sci. 1993 Jun 23;685:746-55. Unique Identifier : AIDSLINE MED/93370924; Laurence J; Hodtsev AS; Posnett DN; Laboratory for AIDS Virus Research, Cornell University Medical; College, New York, New York 10021.
Issues in the development of a prophylactic HIV vaccine.: Ann N Y Acad Sci. 1993 Jun 23;685:777-83. Unique Identifier : AIDSLINE MED/93370931; Hoth DF; Division of AIDS, National Institute of Allergy and Infectious; Diseases, National Institutes of Health, Bethesda, Maryland; 20892.
Trends in human immunodeficiency virus infection: epidemiology in Singapore.: Ann Acad Med Singapore. 1993 Mar;22(2):142-5. Unique Identifier : AIDSLINE MED/93370977; Chew SK; Epidemiology Unit Communicable Disease Centre, Singapore.; The acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency virus (HIV) and recognised a decade ago, has reached pandemic proportions worldwide. By early 1992, the World Health Organisation estimates that at least 10 to 12 million people are infected with HIV globally. The majority of these inf
Altered immunity in haemophiliacs treated exclusively with cryoprecipitate.: Ann Acad Med Singapore. 1993 Mar;22(2):242-6. Unique Identifier : AIDSLINE MED/93370995; Tien SL; Ong YW; Tan P; Tan H; Haematology Department, Singapore General Hospital.; Sixty-five patients with haemophilia A from Singapore General Hospital, treated within the last 15 years exclusively with cryoprecipitate, were studied for the effect of the total number of exposures to random blood donors on their immune system. These haemophiliacs were aged 4
Penicillin-binding proteins of Rhodococcus equi: potential role in resistance to imipenem.: Antimicrob Agents Chemother. 1993 Jul;37(7):1406-9. Unique Identifier : AIDSLINE MED/93371026; Nordmann P; Nicolas MH; Gutmann L; Laboratoire de Microbiologie, Hopital Raymond Poincare,; Faculte de Medecine Paris-Ouest, Garches, France.; Rhodococcus equi is a gram-positive coccobacillus which, like other members of the order Actinomycetales, is increasingly reported as an opportunistic pathogen in patients with AIDS. The use of combinations of antibiotics that include imipenem (IMP) has been suggested for the treatment of patients infected with R. equ
Anti-Pneumocystis carinii activity of PS-15, a new biguanide folate antagonist.: Antimicrob Agents Chemother. 1993 Jul;37(7):1417-9. Unique Identifier : AIDSLINE MED/93371029; Hughes WT; Jacobus DP; Canfield C; Killmar J; Department of Infectious Diseases, St. Jude Children's Research; Hospital, Memphis, Tennessee 38105.; A newly synthesized biguanide inhibitor of dihydrofolate reductase in Plasmodium species was evaluated for its anti-Pneumocystis carinii activity. The compound N-3-(2,4,5-trichlorophenoxypropyloxy)-N -(1-methylethyl)imidoca rbonimidic diamide hydrochloride, designated PS-15, was administered prophylactically and thera
Pharmacokinetic interaction between rifampin and zidovudine.: Antimicrob Agents Chemother. 1993 Jul;37(7):1426-31. Unique Identifier : AIDSLINE MED/93371031; Burger DM; Meenhorst PL; Koks CH; Beijnen JH; Department of Pharmacy, Slotervaart Hospital, Amsterdam, The; Netherlands.; A potential pharmacokinetic interaction between rifampin (Rimactan, Rifadin) and zidovudine ( AZT , Retrovir) was investigated in the population of human immunodeficiency virus-infected patients at our hospital. The results from four patients who were o
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis.: Antimicrob Agents Chemother. 1993 Jul;37(7):1436-43. Unique Identifier : AIDSLINE MED/93371033; Walzer PD; Foy J; Steele P; White M; Cincinnati Veterans Affairs Medical Center, Division of; Infectious Diseases, Ohio.; We compared Ro 11-8958, an analog of trimethoprim (TMP) with improved antimicrobial and pharmacokinetic properties, other dihydrofolate reductase (DHFR) inhibitors, sulfamethoxazole (SMX), and dapsone (DAP) in the treatment of Pneumocystis carinii pneumonia in an immunosuppressed rat model. In contrast to previous rep
Clinical pharmacology [letter]: Arch Dermatol. 1993 Sep;129(9):1205. Unique Identifier : AIDSLINE MED/93371080; Barnett JM
Veridien expects FDA approval soon on HIV virus-killing Sterihol [news]: Ostomy Wound Manage. 1993 May;39(4):65-6. Unique Identifier : AIDSLINE MED/93371661
Antigen presentation, loss of immunological memory and AIDS.: Immunol Today. 1993 Jul;14(7):340-4. Unique Identifier : AIDSLINE MED/93371667; Helbert MR; L'age-Stehr J; Mitchison NA; Robert Koch Institut des Bundesgesundheitsamtes, Berlin, Germany.; A key factor causing immunodeficiency in HIV infection seems to be defective antigen presentation. Consequently, CD4+ T-cell populations, initially those expressing CD45RO, decrease in number not because of their destruction, but because they fail to expand in response to antigenic stimulation. This view implies that
Hematologic aspects of HIV infection [editorial]: AIDS. 1993 Jun;7(6):753-7. Unique Identifier : AIDSLINE MED/93371701; Doweiko JP
A survey of synthetic HIV-1 peptides with natural and chimeric sequences for differential reactivity with Zimbabwean, Tanzanian and Swedish HIV-1-positive sera.: AIDS. 1993 Jun;7(6):759-67. Unique Identifier : AIDSLINE MED/93371702; Blomberg J; Lawoko A; Pipkorn R; Moyo S; Malmvall BE; Shao J; Dash R; Tswana S; Department of Medical Microbiology, University of Lund, Sweden.; OBJECTIVE: To determine whether the known sequence differences between African and non-African HIV-1 strains are reflected in the serological response. DESIGN AND METHODS: We investigated the antibody reactivity of 34 Swedish, 30 Tanzanian and 42 Zimbabwean HIV-1-positive sera to 67 synthetic peptides with sequences f
Phylogenetic analysis of gag genes from 70 international HIV-1 isolates provides evidence for multiple genotypes.: AIDS. 1993 Jun;7(6):769-80. Unique Identifier : AIDSLINE +; Louwagie J; McCutchan FE; Peeters M; Brennan TP; Sanders-Buell E; Eddy GA; van der Groen G; Fransen K; Gershy-Damet GM; Deleys R; et al; Henry M. Jackson Foundation Research Laboratory, Rockville,; Maryland 20850.; OBJECTIVE: To determine the extent of genetic variation among internationally collected HIV-1 isolates, to analyse phylogenetic relationships and the geographic distribution of different variants. DESIGN: Phylogenetic comparison of 70 HIV-1 isolates collected in 15 countries on four continents. METHODS: To sequence th
Protection of monkeys by a split vaccine against SIVmac depends upon biological properties of the challenge virus.: AIDS. 1993 Jun;7(6):787-95. Unique Identifier : AIDSLINE MED/93371705; Stahl-Hennig C; Voss G; Dittmer U; Coulibaly C; Petry H; Makoschey B; Cranage MP; Aubertin AM; Luke W; Hunsmann G; Deutsches Primatenzentrum, Abteilung Virologie und Immunologie,; Gottingen, Germany.; OBJECTIVE: To investigate the role of the anti-cellular immune response in the protection of rhesus macaques against infection with the simian immunodeficiency virus SIVmac. To determine the biological differences between SIV challenge stocks grown either on human T-cell lines or on monkey peripheral blood mononuclear
Augmentation of HIV-specific lymphoproliferation in HIV-infected individuals by TraT: a novel T-cell immunopotentiating agent.: AIDS. 1993 Jun;7(6):807-12. Unique Identifier : AIDSLINE MED/93371708; Bell SJ; Geczy AF; Russell-Jones GJ; Croft S; Cooper DA; Penny R; Centre for Immunology, St Vincent's Hospital, Sydney, New South; Wales, Australia.; OBJECTIVE: To evaluate the potential of TraT to restore HIV-specific cell-mediated immunity. DESIGN: CD4+ T cell-associated antiviral and recall antigen-specific lymphoproliferative responses are generally impaired or absent in HIV-infected individuals. METHODS: Using peripheral blood mononuclear cells (PBMC) from a g
Recombinant alpha-interferon 2b in the treatment of HIV-related thrombocytopenia.: AIDS. 1993 Jun;7(6):823-7. Unique Identifier : AIDSLINE MED/93371710; Vianelli N; Catani L; Gugliotta L; Belmonte MM; Cascione L; Colangeli V; Ricchi E; Mazza P; Mazzucconi MG; Chistolini A; et al; Institute of Haematology, S. Orsola Hospital, Bologna, Italy.; OBJECTIVE: To assess the efficacy and the mechanism of action of alpha-interferon (alpha-IFN) in the treatment of HIV-related thrombocytopenia. METHODS: Thirteen HIV-positive subjects [nine men and four women with severe thrombocytopenia (platelets,
Treatment of cryptococcosis with liposomal amphotericin B (AmBisome) in 23 patients with AIDS.: AIDS. 1993 Jun;7(6):829-35. Unique Identifier : AIDSLINE MED/93371711; Coker RJ; Viviani M; Gazzard BG; Du Pont B; Pohle HD; Murphy SM; Atouguia J; Champalimaud JL; Harris JR; St Mary's Hospital, London, UK.; OBJECTIVE: To determine the safety and efficacy of liposomal amphotericin B (AmBisome) in the primary treatment of AIDS-associated cryptococcosis. DESIGN: A Phase II, multicentre, European, non-comparative, open study to assess the use of AmBisome in 23 patients (26 enrolments) with cryptococcosis. Dose requirements, d
Protein-losing enteropathy and hypoalbuminemia in AIDS.: AIDS. 1993 Jun;7(6):837-40. Unique Identifier : AIDSLINE MED/93371712; Laine L; Garcia F; McGilligan K; Malinko A; Sinatra FR; Thomas DW; Division of Gastroenterology, University of Southern California; School of Medicine, Los Angeles 90033.; OBJECTIVE: To assess the contribution of protein-losing enteropathy to AIDS-associated hypoalbuminemia. DESIGN: Prospective assessment of patients with AIDS. SETTING: An urban county hospital (Los Angeles & University of Southern California Medical Center. USA). PATIENTS: Four groups of patients with AIDS were stud
Sentinel surveillance for HIV-1 among pregnant women in a developing country: 3 years' experience and comparison with a population serosurvey.: AIDS. 1993 Jun;7(6):849-55. Unique Identifier : AIDSLINE MED/93371714; Kigadye RM; Klokke A; Nicoll A; Nyamuryekung'e KM; Borgdorff M; Barongo L; Laukamm-Josten U; Lisekie F; Grosskurth H; Kigadye F; Office of the Regional Commissioner, Mwanza.; OBJECTIVES: To establish unlinked, anonymous sentinel surveillance for HIV-1 among pregnant women attending an antenatal clinic, to determine age-specific seroprevalences, to monitor trends and to compare seroprevalence with that detected by a population serosurvey. To establish the sustainability and costs of surveil
Risk behaviour, anti-HIV and anti-hepatitis B core prevalence in clinic and non-clinic samples of gay men in England, 1991-1992.: AIDS. 1993 Jun;7(6):863-9. Unique Identifier : AIDSLINE MED/93371716; Hart GJ; Dawson J; Fitzpatrick RM; Boulton M; McLean J; Brookes M; Parry JV; Academic Department of Genito-Urinary Medicine, University; College London Medical School, Middlesex Hospital, UK.; OBJECTIVE: To describe the sexual risk behaviour of and HIV and hepatitis B antibody prevalence in gay men in England. DESIGN: Cross-sectional. RESPONDENTS: Gay men recruited from community settings (bars, clubs, gay organizations) and genito-urinary clinics in London, Manchester, the Midlands and Bristol; men who par
Sex role separation in sexual diaries of homosexual men.: AIDS. 1993 Jun;7(6):877-82. Unique Identifier : AIDSLINE MED/93371718; Coxon AP; Coxon NH; Weatherburn P; Hunt AJ; Hickson F; Davies PM; McManus TJ; Department of Sociology, University of Essex, Colchester, UK.; OBJECTIVE: To measure types of sex role prevalence in common and risk-related behaviours among gay men for modelling HIV transmission. DESIGN: Cohort study of 385 homosexually active men recording sexual diaries over 1-month periods. METHODS: Measures of incidence of behavioural sex roles for masturbation, fellatio, a
Condom use with primary partners among injecting drug users in Bangkok, Thailand and New York City, United States.: AIDS. 1993 Jun;7(6):887-91. Unique Identifier : AIDSLINE MED/93371720; Vanichseni S; Des Jarlais DC; Choopanya K; Friedmann P; Wenston J; Sonchai W; Sotheran JL; Raktham S; Carballo M; Friedman SR; Bangkok Metropolitan Administration, Thailand.; OBJECTIVE: To determine factors associated with likelihood or failure to use condoms with primary sexual partners among injecting drug users (IDU) in two cities. DESIGN AND METHODS: Interviews were conducted with 601 IDU in Bangkok in 1989 and with 957 IDU in New York City in 1990-1991. Subjects were recruited from dr
Lack of anti-nuclear antibodies during HIV infection [letter; comment]: AIDS. 1993 Jun;7(6):893. Unique Identifier : AIDSLINE MED/93371721; Lafeuillade A; Ritter J; Pellegrino P; Quilichini R; Monier JC
Secondary diabetes induced by megestrol acetate therapy in a patient with AIDS-associated cachexia [letter]: AIDS. 1993 Jun;7(6):894. Unique Identifier : AIDSLINE MED/93371722; Salinas I; Lucas A; Clotet B
Kussmaul respiration and abdominal pain secondary to metabolic acidosis in AIDS patients with disseminated Mycobacterium avium complex infection receiving clofazimine [letter]: AIDS. 1993 Jun;7(6):894-5. Unique Identifier : AIDSLINE MED/93371723; Soriano V; Moreno V; Alba A; Laguna F; Gonzalez-Lahoz J
Low prevalence of positive tuberculin tests in homo-/bisexual white men from Seattle: implications for anergy testing [letter]: AIDS. 1993 Jun;7(6):895-6. Unique Identifier : AIDSLINE MED/93371724; Nolan CM; Dunphy CA; Krueger LE; Goldbaum GM; Wood RW
Fetal organs infected by HIV-1 [letter]: AIDS. 1993 Jun;7(6):896-7. Unique Identifier : AIDSLINE MED/93371725; Backe E; Unger M; Jimenez E; Siegel G; Schafer A; Vogel M
Conversion of HIV-1 viral markers during the first few months of life in HIV-infected children born to seropositive mothers [letter]: AIDS. 1993 Jun;7(6):897-9. Unique Identifier : AIDSLINE MED/93371726; Denamur E; Levine M; Simon F; Rohrlich P; Cave H; Rahimy C; de Crepy A; Boissinot C; Larchee R; Lescoeur B; et al
Secondary prevention of HIV: knowledge and beliefs about HIV, therapy and community resources [letter]: AIDS. 1993 Jun;7(6):899-900. Unique Identifier : AIDSLINE MED/93371727; Silvestre AJ; Zhou SY; Kingsley LA; Rinaldo CR
Helicobacter pylori infection in an HIV-seropositive patient with diarrhoea [letter; comment]: AIDS. 1993 Jun;7(6):900-1. Unique Identifier : AIDSLINE MED/93371728; Dorrell L; Wardropper AG; Ong EL
AIDS 92/93. Virology: overview.: AIDS. 1993;7 Suppl 1:S1-2. Unique Identifier : AIDSLINE MED/93371730; Kurth R; Wong-Staal F; Paul-Ehrlich-Institute, Langen/Frankfurt, Germany.
AIDS 1992/1993. A year in review.: AIDS. 1993;7 Suppl 1:S1-286. Unique Identifier : AIDSLINE MED/93371731
Epidemiology of tuberculosis in the era of HIV.: AIDS. 1993;7 Suppl 1:S109-14. Unique Identifier : AIDSLINE MED/93371732; Horsburgh CR Jr; Pozniak A; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.
AIDS 92/93. Vaccines and immunology: overview.: AIDS. 1993;7 Suppl 1:S115-6. Unique Identifier : AIDSLINE MED/93371733; Girard MP; Shearer GM; Institut Pasteur, Paris, France.
Cell-mediated immunity in HIV infection.: AIDS. 1993;7 Suppl 1:S135-40. Unique Identifier : AIDSLINE MED/93371736; Clerici M; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.
Use of new vectors for the development of vaccines.: AIDS. 1993;7 Suppl 1:S141-6. Unique Identifier : AIDSLINE MED/93371737; Adams SE; Paoletti E; British Bio-technology Ltd, Oxford, England, UK.
Human trials of experimental AIDS vaccines.: AIDS. 1993;7 Suppl 1:S147-59. Unique Identifier : AIDSLINE MED/93371738; Fast PE; Walker MC; Vaccine Research and Development Branch, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, Maryland 20892.
Primate models for HIV vaccines.: AIDS. 1993;7 Suppl