Peripheral neuropathy in a cohort of human immunodeficiency virus-infected patients. Incidence and relationship to other nervous system dysfunction. NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Peripheral neuropathy in a cohort of human immunodeficiency virus-infected patients. Incidence and relationship to other nervous system dysfunction.

Arch Neurol. 1991 Dec;48(12):1273-4. Unique Identifier : AIDSLINE MED/93263832
Hall CD; Snyder CR; Messenheimer JA; Wilkins JW; Robertson WT; Whaley RA; Robertson KR; AIDS Neurologic Center, University of North Carolina School of; Medicine, Chapel Hill 27599-7025.


Abstract: A cohort of 94 patients infected with human immunodeficiency virus was evaluated clinically and electrophysiologically for the presence of peripheral neuropathy, and the results were compared with evaluations of central nervous system function. Thirty-two (34%) had some degree of peripheral neuropathy; 18 (19%) (six [12%] of the 49 asymptomatic patients, five [45%] of the 11 patients with acquired immunodeficiency syndrome [AIDS], and seven [21%] of the 34 patients with AIDS-related complex) had neuropathy on clinical examination; and 21 (23%) (eight [16%] asymptomatic, four [36%] AIDS, and nine [26%] AIDS-related complex) had neuropathy on electrophysiologic evaluation. There was a significant correlation between the presence of neuropathy and evidence of central nervous system dysfunction.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/PHYSIOPATHOLOGY Brain/PHYSIOPATHOLOGY Evoked Potentials Human HIV Infections/*COMPLICATIONS/PHYSIOPATHOLOGY Neural Conduction Peripheral Nervous System Diseases/*ETIOLOGY/PHYSIOPATHOLOGY Reaction Time Support, U.S. Gov't, P.H.S. JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDcomplications/physiopathologybrain/physiopathologyevokedpotentialshumanhivinfections/KWDcomplications/physiopathologyneuralconductionperipheralnervoussystemdiseases/KWDetiology/physiopathologyreactiontimesupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
930830
M9380790

Copyright © 1993 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1993. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1993. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .