HTLV-I-associated myelopathy (HAM/TSP) with Hashimoto's thyroiditis. NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

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HTLV-I-associated myelopathy (HAM/TSP) with Hashimoto's thyroiditis.

Tokushima J Exp Med. 1991 Dec;38(3-4):99-102. Unique Identifier : AIDSLINE MED/93118037
Kawai H; Kashiwagi S; Inui T; Tamaki Y; Sano Y; Saito S; 1st Department of Internal Medicine, School of Medicine,; University of Tokushima, Japan.

Abstract: Two cases of HTLV-I-associated myelopathy (HAM/TSP) with Hashimoto's thyroiditis are reported. One patient is a 47-year-old female with goiter and the other a 60-year-old female. Both have slowly progressive spastic paraparesis and have anti-HTLV-I antibodies in their serum and cerebrospinal fluid. Anti-thyroid antibodies are also present in their serum, and biopsy specimens of their thyroids showed the pathological features of Hashimoto's thyroiditis. The association of the two disorders in these patients provides further evidence for the autoimmune hypothesis of the pathogenesis of HAM/TSP, and also suggests a relationship of Hashimoto's thyroiditis with HTLV-I infection.
Keywords: Autoimmunity Case Report Female Human Middle Age Paraparesis, Tropical Spastic/*COMPLICATIONS/IMMUNOLOGY Thyroiditis, Autoimmune/*COMPLICATIONS JOURNAL ARTICLEKWDautoimmunitycasereportfemalehumanmiddleageparaparesis,tropicalspastic/KWDcomplications/immunologythyroiditis,autoimmune/KWDcomplicationsjournalarticle
930430
M9340811

Copyright © 1993 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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