Pneumocystis carinii pleuropneumonia after aerosolized pentamidine prophylaxis. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Pneumocystis carinii pleuropneumonia after aerosolized pentamidine prophylaxis.

Infection. 1991 Nov-Dec;19(6):442-4. Unique Identifier : AIDSLINE MED/92275826
Ewig S; von Kempis J; Rockstroh J; Steudel A; Vogel J; Niese D; Medizinische Klinik, Universitat Bonn, Germany.

Abstract: We observed an atypical Pneumocystis infection with spontaneous pneumothorax, bronchopleural fistulae, an apical cyst and Pneumocystis pleuritis after aerosolized pentamidine prophylaxis in an AIDS patient. These findings suggest a failure of pentamidine aerosol in controlling active Pneumocystis infection in peripheral pulmonary areas. A relapse of Pneumocystis carinii pneumonia (PCP) must be suspected when pneumothorax occurs during secondary prophylaxis with aerosolized pentamidine. It should always be confirmed by bronchoalveolar lavage or transbronchial or open biopsy. Cases presenting as atypical Pneumocystis pneumonia may additionally reveal extrapulmonary dissemination of Pneumocystis infection.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Administration, Inhalation Adult Aerosols Case Report Hemophilia/COMPLICATIONS Human Male Pentamidine/*ADMINISTRATION & DOSAGE Pleuropneumonia/COMPLICATIONS/MICROBIOLOGY/*PREVENTION & CONTROL Pneumonia, Pneumocystis carinii/COMPLICATIONS/MICROBIOLOGY/ *PREVENTION & CONTROL Pneumothorax/COMPLICATIONS JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadministration,inhalationadultaerosolscasereporthemophilia/complicationshumanmalepentamidine/KWDadministration&dosagepleuropneumonia/complications/microbiology/KWDprevention&controlpneumonia,pneumocystiscarinii/complications/microbiology/KWDprevention&controlpneumothorax/complicationsjournalarticle
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M9290886

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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