Surgical treatment of myasthenia gravis and evaluation of its efficacy. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Surgical treatment of myasthenia gravis and evaluation of its efficacy.

J Tongji Med Univ. 1991;11(2):106-10. Unique Identifier : AIDSLINE MED/92277714
Pan TC; Chen QF; Zhang LH; Shen YZ; Xie ZP; Yang MS; Bu BT; Cao XB; Department of Surgery, Tongji Hospital, Tongji Medical; University, Wuhan.

Abstract: This paper reports 30 cases of myasthenia gravis (MG) treated by thymectomy from 1965 to 1990 in our hospital. Of all the 30 cases of MG, peripheral blood lymphocyte subpopulation was determined in 10, and anti-acetylcholine receptor antibody titer in 6, before and after operation. The results demonstrated the efficacy of thymectomy against MG. We considered that with application of hormone before and after operation to regulate immune function of the body, and/or with plasma exchange to remiss symptoms, all the patients with generalized MG may be indicated for treatment by thymectomy. Indication of treatment does not depend on age, sex and the course of the disease. But radical operation, proper anesthesia and appropriate use of antibiotics may ensure safety of the operation and its curative effect.
Keywords: Adolescence Adult Child CD4-CD8 Ratio Female Human Male Middle Age Myasthenia Gravis/ETIOLOGY/IMMUNOLOGY/*SURGERY T-Lymphocyte Subsets/IMMUNOLOGY Thymectomy/METHODS Thymoma/COMPLICATIONS Thymus Hyperplasia/COMPLICATIONS Thymus Neoplasms/COMPLICATIONS JOURNAL ARTICLEKWDadolescenceadultchildcd4-cd8ratiofemalehumanmalemiddleagemyastheniagravis/etiology/immunology/KWDsurgeryt-lymphocytesubsets/immunologythymectomy/methodsthymoma/complicationsthymushyperplasia/complicationsthymusneoplasms/complicationsjournalarticle
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M9290878

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