GENE REGULATION AND AIDS: TRANSCRIPTIONAL ACTIVATION, RETROVIRUSES AND PATHOGENESIS NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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GENE REGULATION AND AIDS: TRANSCRIPTIONAL ACTIVATION, RETROVIRUSES AND PATHOGENESIS

Adv Appl Biotech Ser; 7:1-386 1990. Unique Identifier : AIDSLINE ICDB/92686358
Anonymous; No affiliation given

Abstract: This book consists of papers selected from those presented at the First International Conference on Gene Regulation, Oncogenesis, and AIDS. From the extensive amount of information presented on the interrelationship of research in oncogenesis and AIDS, two volumes were prepared. The first is comprised of papers presented on oncogenesis (in the CANCERLIT data base with accession numbers ICDB91077155-ICDB91077180). The current volume consists of papers on gene regulation and AIDS, AIDS and human retroviruses, and retroviruses and pathogenesis. Among the topics presented are the following: GCN4, the yeast version of the jun-fos oncogene family; leucine zippers control the DNA binding potential of fos, jun and GCN4; different proteins bind to the phorbol ester-responsive sequences in collagenase and c-jun promoters; cloning of cDNAs for proteins binding to the MuLV enhancer region; genetic regulation of HIV; regulation of HIV-1 expression by viral factors; proviral human immunodeficiency virus present in CD4+ peripheral blood T lymphocytes; immunogenicity of human retrovirus-specific proteins; prospects for prevention of pediatric AIDS; the HIV protease and the human CD4 receptor as molecular targets for AIDS therapeutics; regulation of expression of the equine infectious anemia virus genome; controlling bovine leukemia virus infection--development of a specific serologic test and an efficient subunit vaccine; and human herpesvirus-6--replication and cell membrane fluidity changes in immature prethymic T cells.
Keywords: Acquired Immunodeficiency Syndrome/*GENETICS Africa, Western/EPIDEMIOLOGY Antigens, CD4/GENETICS Antigens, Polyomavirus Transforming/METABOLISM Chickens Child Crystallins/GENETICS DNA/GENETICS DNA-Binding Proteins/GENETICS/METABOLISM Enhancer Elements (Genetics) *Gene Expression Regulation, Viral Gene Products, tat/GENETICS/ISOLATION & PURIF/METABOLISM Genes, fos Genes, gag Genes, jun Genes, myc Genes, pX Genes, Viral Herpesviridae/METABOLISM/PHYSIOLOGY/PATHOGENICITY Human HIV Infections/EPIDEMIOLOGY/PHYSIOPATHOLOGY HIV Long Terminal Repeat HIV Protease/METABOLISM HIV-1/GENETICS HIV-2 Leucine Zippers/GENETICS Oncogenes Promoter Regions (Genetics) Rats Retroviridae/*GENETICS RNA Polymerases/GENETICS RNA-Directed DNA Polymerase/METABOLISM RNA, Catalytic/PHARMACOLOGY T-Phages/ENZYMOLOGY *Trans-Activation (Genetics) Virus Replication Xenopus laevis MONOGRAPHKWDacquiredimmunodeficiencysyndrome/KWDgeneticsafrica,western/epidemiologyantigens,cd4/geneticsantigens,polyomavirustransforming/metabolismchickenschildcrystallins/geneticsdna/geneticsdna-bindingproteins/genetics/metabolismenhancerelements(genetics)
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Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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