Neuropsychological effects of early HIV-1 infection: assessment and methodology.

Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

Neuropsychological effects of early HIV-1 infection: assessment and methodology.

J Neuropsychiatry Clin Neurosci. 1990 Spring;2(2):174-82. Unique Identifier : AIDSLINE MED/92330386
Ingraham LJ; Bridge TP; Janssen R; Stover E; Mirsky AF; Laboratory of Psychology and Psychopathology, National Institute; of Mental Health, National Institutes of Health, Bethesda, MD; 20892.

Abstract: Studies of neuropsychological performance early in the course of human immunodeficiency virus-type 1, infection are reviewed. The studies differed on reporting the presence and severity of neuropsychological changes, and comparisons among studies are hampered by variations in the study populations, sample sizes, assessment methods, approaches to data analysis, and definitions of thresholds for abnormality. Recommendations that would facilitate comparisons among future studies include using markers for disease state, applying longitudinal designs, using common instruments for assessing neuropsychological status, selecting appropriate controls, controlling for co-factors, reporting raw scores as well as presumed indices of impairment, and relating impairment on neuropsychological tests to affected individuals' daily activities, if possible.

Keywords: Acquired Immunodeficiency Syndrome/DIAGNOSIS/PSYCHOLOGY Activities of Daily Living/PSYCHOLOGY AIDS Dementia Complex/*DIAGNOSIS/PSYCHOLOGY AIDS-Related Complex/DIAGNOSIS/PSYCHOLOGY Human HIV Seropositivity/DIAGNOSIS/PSYCHOLOGY HIV-1/*PATHOGENICITY *Neuropsychological Tests JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL
921030
M92A1019

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