Cognitive deficits associated with human immunodeficiency virus encephalopathy.

Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

Cognitive deficits associated with human immunodeficiency virus encephalopathy.

J Neuropsychiatry Clin Neurosci. 1990 Summer;2(3):256-60. Unique Identifier : AIDSLINE MED/92330397
Krikorian R; Wrobel AJ; Meinecke C; Liang WM; Kay J; Department of Psychiatry, University of Cincinnati College of; Medicine, OH 45267-0559.

Abstract: The encephalopathy associated with direct nervous system infection by the human immunodeficiency virus (HIV) has been recognized as one of the major debilitating aspects of the acquired immunodeficiency syndrome (AIDS) and of pre-AIDS conditions. A comprehensive neuropsychological examination of symptomatic HIV-infected subjects without opportunistic cerebral disease demonstrated a distinctive pattern of cognitive deficits marked by prominent attentional impairment. Evidence of organizational and reasoning impairments also was observed, but language, visual-spatial, and memory consolidation abilities were relatively preserved. The findings suggest a profile of impairment similar to other cognitive syndromes involving dysfunction of predominantly anterior brain structures and projections and suggest a rationale for psychostimulant drug treatment.

Keywords: Adult Attention AIDS Dementia Complex/*DIAGNOSIS/PSYCHOLOGY Bisexuality/PSYCHOLOGY Cognition Disorders/*DIAGNOSIS/PSYCHOLOGY Homosexuality/PSYCHOLOGY Human Male *Neuropsychological Tests Orientation Psychomotor Performance Recall JOURNAL ARTICLE
921030
M92A1017

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