[Clinical description of three cases of cerebral cryptococcosis in patients with AIDS treated with fluconazole] NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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[Clinical description of three cases of cerebral cryptococcosis in patients with AIDS treated with fluconazole]

Riv Eur Sci Med Farmacol. 1991 May-Aug;13(3-4):173-7. Unique Identifier : AIDSLINE MED/92327367
Izzo E; Piccinino R; Caruso I; Bisogno A; Pesce G; Liberti A; III Divisione, Presidio Ospedaliero, D. Cotugno Specializzato in; Malattie Infettive, USL 41, Regione Campania.

Abstract: The authors have evaluated the efficacy of Fluconazole (400 mg/iv/die for three days and after 200 mg/iv/die for 18 days) in three AIDS and SNC Cryptococcal infection patients. Two patients have shown healing of meningeal syndrome and negative isolation after 21 days of therapy; one patient, however, died because of Cytomegalovirus pneumonia. It is of note that early spinal puncture in AIDS patients with neurological symptoms enables an early diagnosis and immediate therapy. Fluconazole treatment has been well tolerated and immediately effective to resolve two of the cases observed; the oral prophylaxis with 100 mg/die of Fluconazole after 6 months has been effective to prevent the relapses of the disease.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Brain Diseases/*DRUG THERAPY Case Report Cryptococcosis/COMPLICATIONS/*DRUG THERAPY English Abstract Fluconazole/*THERAPEUTIC USE Human Male JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultbraindiseases/KWDdrugtherapycasereportcryptococcosis/complications/KWDdrugtherapyenglishabstractfluconazole/KWDtherapeuticusehumanmalejournalarticle
921030
M92A0991

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