Longitudinal evaluation of neuropsychological function in homosexual men with HIV infection: 18-month follow-up. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Longitudinal evaluation of neuropsychological function in homosexual men with HIV infection: 18-month follow-up.

J Neuropsychiatry Clin Neurosci. 1991 Summer;3(3):286-98. Unique Identifier : AIDSLINE MED/92330445
Saykin AJ; Janssen RS; Sprehn GC; Kaplan JE; Spira TJ; O'Connor B; Department of Psychiatry, University of Pennsylvania,; Philadelphia 19104.


Abstract: Subjects were 21 men with persistent generalized lymphadenopathy (PGL, n = 13) or AIDS-related complex (ARC, n = 8), who were not receiving anti-retroviral medication, and 21 controls. At baseline, mild cognitive impairment was detected in language, memory, attention, and visual and auditory processing, primarily in patients with ARC. On follow-up, the ARC group showed continued impairment and abnormalities on new measures of distractibility and activities of daily living. Although mild decline in verbal memory was noted for some patients, overall neuropsychological profiles did not show deterioration. Nomenclature for the pattern of mild, stable neuropsychological changes in patients with cognitive symptoms is discussed. Two interdisciplinary panels have recommended the term HIV-1-associated minor cognitive/motor disorder. Unlike the term AIDS dementia, it does not imply progression or a diagnosis of AIDS.
Keywords: Activities of Daily Living/PSYCHOLOGY Adaptation, Psychological Adult Affective Symptoms/DIAGNOSIS/PSYCHOLOGY Attention AIDS Dementia Complex/*DIAGNOSIS/PSYCHOLOGY Bisexuality/*PSYCHOLOGY Homosexuality/*PSYCHOLOGY Human Longitudinal Studies Male Neurologic Examination *Neuropsychological Tests Personality Disorders/DIAGNOSIS/PSYCHOLOGY Psychomotor Performance Recall Retrospective Studies Sick Role JOURNAL ARTICLEKWDactivitiesofdailyliving/psychologyadaptation,psychologicaladultaffectivesymptoms/diagnosis/psychologyattentionaidsdementiacomplex/KWDdiagnosis/psychologybisexuality/KWDpsychologyhomosexuality/KWDpsychologyhumanlongitudinalstudiesmaleneurologicexaminationKWDneuropsychologicaltestspersonalitydisorders/diagnosis/psychologypsychomotorperformancerecallretrospectivestudiessickrolejournalarticle
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Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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