LUNG CANCER IN HIV-INFECTED PATIENTS (MEETING ABSTRACT)

Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

LUNG CANCER IN HIV-INFECTED PATIENTS (MEETING ABSTRACT)

Proc Annu Meet Am Soc Clin Oncol; 11:A15 1992. Unique Identifier : AIDSLINE ICDB/92680746
Sridhar KS; Flores MR; Raub W; Thurer R; Horowitz M; Sylvester Cancer Center, Univ. of Miami Sch. of Medicine, Miami,; FL

Abstract: This retrospective study determined the clinical course of lung cancer in patients (pts) with human immunodeficiency virus (HIV) infection. Twenty-four pts with HIV infection archived as lung cancer were studied. Seventeen were identified from about 1000 lung cancer pts entered in the tumor registry and medical records of Jackson Memorial Hospital. Seven more were identified from about 1000 HIV-positive pts entered in the Special Immunology registry of Veteran's Administration Medical Center. Four pts did not have pathologic confirmation of lung cancer and, in one, metastatic esophageal cancer was established. Nineteen pts, all men, met the criteria for analysis (histopathologic diagnosis of lung cancer and HIV+ by serology). The median age (and range) was 48 (36-66) yr. Risk factors for HIV were homosexuality (6 pts), blood transfusion (3), heterosexual promiscuity (5), iv drug abuse (3), and none (3). Six pts had pulmonary tuberculosis and 5 had Pneumocystis carinii pneumonia. Histologic subtypes were adeno: 8, squamous: 6, and others: 5. Lung cancer stages were I: 3, II: 1, III: 5, and IV: 10. CDC stages of HIV infection were I: 0, II: 5, III: 4, and IV: 10. Median survival from advanced stages of both HIV infection and lung cancer may account for the poor survival. All pts with both lung cancer and HIV infection reported so far were men and noted to be younger than other pts with lung cancer.

Keywords: Adenocarcinoma/ETIOLOGY/PATHOLOGY Carcinoma, Squamous Cell/ETIOLOGY/PATHOLOGY Female Florida Homosexuality Hospitals, University Hospitals, Veterans Human HIV Infections/*COMPLICATIONS HIV Seropositivity Lung Neoplasms/*ETIOLOGY/*PATHOLOGY Male Middle Age Neoplasm Staging Pneumonia, Pneumocystis carinii/ETIOLOGY Registries Sex Behavior Substance Abuse Tuberculosis, Pulmonary/ETIOLOGY ABSTRACT

921130
M92B0894

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1992. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1992. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .