Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.
HODGKIN'S LYMPHOMA AND AIDS EPIDEMIC IN KENYA (MEETING ABSTRACT)
Second International Symposium on Hodgkin's Disease, October 3-5, 1991, Cologne, Germany, p. 31, 1991.. Unique Identifier : AIDSLINE ICDB/92679728 Nyongo A; Abinya NO; Nyabola J; Univ. of Nairobi, P.O. Box 19676, Nairobi, Kenya
Abstract:
In order to show changes in the Hodgkin's lymphoma (HL) pattern in Kenya after the onset of the AIDS epidemic, a retrospective study was undertaken using Kenya Cancer Registry material. The HL diagnoses made from 1/1/68 to 12/31/87 were reevaluated. There were 685 cases (520 males, 165 females). The annual rate ranged from 11 in 1987 to 58 in 1968 with a mean of 34.8. 49% of the cases were under the age of 20 yr; 135 (19.4%) being under the age of 10. Only 84 (12%) were over 40. The age group 10-19 yr of age had the highest frequency (30%). Distribution according to districts showed a predilection for high altitude and tea-growing areas as opposed to lowlands. No clustering was seen in the districts with the highest incidence of AIDS. The male:female ratio decreased from 4.8:1 in the 1968-72 period to 2.9:1 in the 1983-87 period. Of 430 (62%) which were histologically subclassified, 201 (46.8%) were of mixed cellularity, 56 (12%) were nodular-sclerosing, 57 (12%) were lymphocyte-predominant and 116 (30%) were lymphocyte-depleted type. Sex ratio, age distribution and histologic subtypes show a different pattern from that seen in the West. The disease prevalence has not increased with the advent of AIDS except that it seems the frequency in females has increased. There seems to be an association between HL and tea-growing high altitude areas.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/*EPIDEMIOLOGY Adolescence Adult Child Female Hodgkin's Disease/COMPLICATIONS/*EPIDEMIOLOGY Human Kenya/EPIDEMIOLOGY Male Retrospective Studies ABSTRACT
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