Stereotactic biopsy of cerebral lesions in patients with AIDS [see comments] NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Stereotactic biopsy of cerebral lesions in patients with AIDS [see comments]

Br J Neurosurg. 1991;5(6):585-9. Unique Identifier : AIDSLINE MED/92126248
Pell MF; Thomas DG; Whittle IR; National Hospital for Neurology and Neurosurgery, London.

Abstract: Central nervous system involvement with AIDS is not uncommon. The indications and timing of brain biopsy remains controversial. Stereotactic CT-guided biopsy offers a safe and effective means of establishing a diagnosis in any patient with a cerebral mass lesion and has less morbidity and mortality than freehand biopsy or exploratory craniotomy. Eleven patients with AIDS have undergone CT-directed stereotactic biopsy between May 1987 and November 1990 with one death from intracerebral haemorrhage. Histological diagnosis of the biopsy specimens showed multifocal leucoencephalopathy, toxoplasmosis, lymphoma and non-specific changes. Biopsy is recommended for patients with an atypical presentation, negative serology, progressive clinical deterioration and differential response of lesions to empirical therapy.
Keywords: Adult AIDS Dementia Complex/*PATHOLOGY/RADIOGRAPHY Biopsy/*METHODS Brain/*PATHOLOGY/RADIOGRAPHY Female Human Male Middle Age *Stereotaxic Techniques Support, Non-U.S. Gov't Tomography, X-Ray Computed JOURNAL ARTICLE

KWDadultaidsdementiacomplex/KWDpathology/radiographybiopsy/KWDmethodsbrain/KWDpathology/radiographyfemalehumanmalemiddleageKWDstereotaxictechniquessupport,non-uKWDsKWDgov'ttomography,x-raycomputedjournalarticle
Comment in: Br J Neurosurg 1992;6(5):505-6
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M9250932

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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