1992

AIDS, the litmus test for humanity in the 80's. [videorecording]
[St. Louis, Mo.] : CHA, c1988 1 videocassette (31 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9200148A
Barcus W
Facing our fears : mental health providers & AIDS. [videorecording]
San Francisco, CA : AIDS Health Project, c1988 1 videocassette : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9200157A
Helquist M; Goldblum P
Now that you know : living healthy with HIV. [videorecording]
Los Angeles, CA : Kaiser Permanente Audio-Visual Services, c1991 4 videocassettes (196 min., 31 sec.) : sd., col. ; 1/2 in. + 1 guide Unique Identifier : AIDSLINE AV/9200170A
Bunker J
Women and HIV infection. [sound recording]
[Califon, N.J.] : Gardiner-Caldwell SynerMed, c1991 1 sound cassette : analog Unique Identifier : AIDSLINE AV/9200187A
[Tabuthema Aids-Stop : zwischen Monogamie-Propaganda und grunem Licht fur Virus-Ubertrager : Gedanken eines Ketzers.] 1. Aufl.
Freiburg : Ahriman, c1986 81 p. : ill (Ahriman Flugschrift ; Nr. 1) Unique Identifier : AIDSLINE CAT/9201494
Hoevels FE
Epidemiology of AIDS (acquired immune deficiency syndrome).
[Carbondale, IL] (P.O. Box 3158, Carbondale 62902) : Educational Research Corp., c1987- v Unique Identifier : AIDSLINE CAT/9200967
Stanley GL; Stanley SJ; Continuing Education; Careers
[SIDA en Afrique : maladie et phenomene social.]
Kinshasa, Zaire : Editions Centre de Vulgarisation Agricole, 1988 85 p. : ill Unique Identifier : AIDSLINE CAT/9201491
Bila KM
[Het:Ontstaan van AIDS in het licht van de homeopathie.]
[Rijswijk : Elmar, 1988?] 204 p. : ill Unique Identifier : AIDSLINE CAT/9202111
Vithoulkas G
Washington area directory of experimental treatments for HIV-related illnesses. -Mar. 15, 1989.
[Washington, D.C. : Whitman-Walker Clinic, v Unique Identifier : AIDSLINE CAT/9201527
APHA/SIA report. 1 (July 1988)-
Washington, D.C. : Special Initiative on AIDS, American Public Health Association, 1988- v Unique Identifier : AIDSLINE CAT/9201865
Miami's attention to AIDS : commitment to prevention.
Development Washington, D.C. : The League, c1989 vii, 186 p Unique Identifier : AIDSLINE CAT/9200837
AIDS service directory for hispanics = Directorio de los servicios de asistencia del SIDA para los Hispanos.
Organizations (U.S.) Washington, D.C. (1030 15th St., N.W., Suite 1053, Washington 20005) : National Coalition of Hispanic Health and Human Services Organizations, [1989?] xiv, 208 p Unique Identifier : AIDSLINE CAT/9200787
[AIDS-Ratgeber : Praxishilfe fur Berater und Betroffene.]
Koln : Bund-Verlag, c1989 95 p Unique Identifier : AIDSLINE CAT/9201192
Baer U
[Pripad AIDS.]
Bratislava : Mlade leta, 1989 86 p. : port Unique Identifier : AIDSLINE CAT/9201072
Strmenova J
Preventing AIDS : a guide to effective education for the prevention of HIV infection.
Washington, D.C. : American Public Health Association, c1989 xvi, 217 p. : ill Unique Identifier : AIDSLINE CAT/9201431
Freudenberg N
[Public Relations offentlicher Verwaltungen gegen die Immunschwachekrankheit AIDS : Uberblick und Wirkungsanalyse ausgewahlter PR-Massnahmen.]
Wiesbaden : Verlag fur deutsche Wirtschaftsbiographien, 1989 ix, 248 p. : ill (Studien zu Theorie und Praxis der Public Relations ; Bd. 43) Unique Identifier : AIDSLINE CAT/9201442
Kehl T
David Suzuki talks about AIDS. Australian ed.
Sydney : Allen & Unwin, 1989 vi, 112 p. : ill Unique Identifier : AIDSLINE CAT/9201915
Suzuki DT; Thalenberg E; Knudtson P
[Stadte und AIDS.]
Koln : Deutscher Stadtetag, 1989 62 p (DST-Beitrage zur Sozialpolitik. Reihe D, ISSN 0344-2470 ; Heft 23) Unique Identifier : AIDSLINE CAT/9201486
Baltimore-Washington area directory of experimental treatments for HIV-related illnesses. Vol. 1, no. 4 (June 15, 1989)-
Washington, D.C. : Whitman-Walker Clinic, 1989- v Unique Identifier : AIDSLINE CAT/9201577
Directory of research studies being conducted. Alphabetical listing by institutions. Entries give such information as topic of study, inclusion criteria, administration, cost, duration, and contact person.


[Deutsche AIDS-Hilfe Aktuell.] Sept./Okt. 1989-
Berlin : Deutsche AIDS-Hilfe e.V., [1989- v. : ill., ports Unique Identifier : AIDSLINE CAT/9201925
HIV/AIDS surveillance report. Sept. 30, 1989-
Portland, Or. : Health Division, HIV Program, [1989- v. : ill Unique Identifier : AIDSLINE CAT/9201659
AIDS hotline training manual. Rev.
San Francisco, CA : San Francisco AIDS Foundation, 1990 66 p Unique Identifier : AIDSLINE CAT/9200904
Frutschey C; Christen P; Rittinger D
AIDS and the mouth : diagnosis and management of oral lesions.
Copenhagen : Munksgaard ; Chicago, Ill. : Distributed in North and South America by Mosby-Year Book, c1990 204 p. : ill Unique Identifier : AIDSLINE CAT/9200786
Greenspan D
Homoeopathy : an anti-AIDS treatment. 1st ed.
New Delhi : Mittal Publications, 1990 84 p Unique Identifier : AIDSLINE CAT/9200997
Ismail SM
[Programm und Abstracts.]
Munchen : Futuramed, c1990 559, xlvii p. : ill., ports Unique Identifier : AIDSLINE CAT/9201436
[SIDA : de la biomedicina a la sociedad.]
Madrid : Eudema, c1990 421 p. : ill Unique Identifier : AIDSLINE CAT/9201492
Najera R
[Aktuelle Neuropadiatrie 1989 : progrediente Enzephalopathie-Syndrome, Multiple Sklerose, HIV-Infektion, benigne fokale Epilepsien.]
Berlin ; New York : Springer-Verlag, c1990 xxi, 389 p. : ill Unique Identifier : AIDSLINE CAT/9201562
Hanefeld F
[AIDS-Kompendium : aktuelle Ubersicht, Klinik und Forschung.]
Stuttgart ; New York : Schattauer, c1990 x, 138 p. : ill (Uni-Taschenbucher ; 1580. Innere Medizin, Immunologie) Unique Identifier : AIDSLINE CAT/9201575
Kallage J
Guidelines for counselling about HIV infection and disease.
Geneva : World Health Organization, 1990 v, 48 p. : ill (WHO AIDS series, ISSN 1011-5773 ; 8) Unique Identifier : AIDSLINE CAT/9201640
Washington-Baltimore HIV research directory. Vol. 2, no. 1 (Mar. 1990)-
Washington, D.C. : Whitman-Walker Clinic, c1990- v Unique Identifier : AIDSLINE CAT/9201813
Listings of area experimental treatment studies, arranged by institutions. Entries give such information as drug contact, follow-up, cost, and duration. Index.


Annotated client education directory : women, AIDS, and drug use. Rev. ed.
[Bethesda, Md.] : Nova Research Company, [1991] iv, 233 p Unique Identifier : AIDSLINE CAT/9200782
[Infections a V.I.H. et reproduction.]
Paris : Arnette, 1991 237 p. : ill Unique Identifier : AIDSLINE CAT/9201331
Blanc B
You and HIV : a day at a time.
Philadelphia : W.B. Saunders, c1991 xiii, 258 p. : ill Unique Identifier : AIDSLINE CAT/9202233
Baker LS
Viruses that affect the immune system.
Washington, D.C. : American Society for Microbiology, c1991 ix, 249 p. : ill (ICN-UCI conferences in virology) Unique Identifier : AIDSLINE CAT/9202219
Fan H
HIV screening of pregnant women and newborns.
Washington, D.C. : National Academy Press, 1991 x, 146 p. : ill Unique Identifier : AIDSLINE CAT/9202000
Hardy LM; Screening for HIV Infection
ABC of AIDS. 2nd ed.
London : British Medical Journal, 1991 72 p. : ill Unique Identifier : AIDSLINE CAT/9201863
Adler MW; Beverley PC
AIDS and the public work force : local government preparedness in managing the epidemic.
Tuscaloosa : University of Alabama Press, c1991 xii, 182 p Unique Identifier : AIDSLINE CAT/9201864
Slack JD
Women at risk : an annotated bibliography.
[Bethesda, Md.] : Nova Research Company, [1991] i, 142 p Unique Identifier : AIDSLINE CAT/9200874
Science challenging AIDS. Abstracts.
Rome, Italy : The Conference, [1991?] 2 v Unique Identifier : AIDSLINE CAT/9200856
HIV infection and intravenous drug use.
Westport, Conn. : Praeger, 1992 xii, 137 p. : ill Unique Identifier : AIDSLINE CAT/9200817
Ottomanelli G
HIV and AIDS : management by the primary care team.
Oxford ; New York : Oxford University Press, 1992 vii, 104 p (Practical guides for general practice ; 16) Unique Identifier : AIDSLINE CAT/9201004
Moss A
Some call it AIDS, I call it murder : the connection between cancer, AIDS, immunizations, and genocide.
San Antonio : AUM Publications, c1992 2 v. (xvii, x, 968 p.) : ill Unique Identifier : AIDSLINE CAT/9201478
Snead EL
AIDS and other manifestations of HIV infection. 2nd ed.
New York : Raven Press, c1992 xxi, 715 p. : ill Unique Identifier : AIDSLINE CAT/9201574
Wormser GP
Assessing AIDS prevention : selected papers presented at the international conference held in Montreux (Switzerland), October 29-November 1, 1990.
Basel ; Boston : Birkhauser, c1992 x, 305 p. : ill Unique Identifier : AIDSLINE CAT/9201859
Paccaud F; Vader JP; Gutzwiller F
DRUG SYNERGISM, ANTAGONISM, AND COLLATERAL SENSITIVITY INVOLVING GENETIC CHANGES
Synergism and Antagonism in Chemotherapy. Chou TC and Rideout DC, eds. New York, Academic, p. 585-619, 1991.. Unique Identifier : AIDSLINE ICDB/92678590
Avramis VI; Huang SH; Holcenberg JS; Div. of Hematology-Oncology, Children's Hosp. of Los Angeles,; Univ. of Southern California, P.O. Box 54700, Los Angeles, CA; 90054-0070
Drug synergism is defined as a significant improvement in pharmacologic action when two or more drugs are used in combination. Drug antagonism is defined as a reduced pharmacologic effect when two or more drugs are administered in combination. The actions of drugs will be altered when specific gene products that contr


SELECTIVE SYNERGISM AGAINST THE TARGET VERSUS HOST BONE MARROW PROGENITOR CELLS
Synergism and Antagonism in Chemotherapy. Chou TC and Rideout DC, eds. New York, Academic, p. 715-37, 1991.. Unique Identifier : AIDSLINE ICDB/92678594
Berman E; Chang TT; Dept. of Medicine, Memorial Sloan-Kettering Cancer Center, New; York, NY 10021
Clinical drug trials designed to assess synergy in vivo are difficult to interpret given such variables as drug absorption, protein binding, and metabolic degradation pathways. A quantitative approach to data interpretation in both infectious disease studies and oncology may prove useful to the clinician designing com


THE HUMAN RETROVIRUSES
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, 421 p., 1991.. Unique Identifier : AIDSLINE ICDB/92678718
Anonymous; No affiliation given
Until about 1950, RNA tumor viruses, as retroviruses were then called, were only known in chickens. The mouse mammary tumor virus had been discovered in the 1930s, but it was not recognized as an RNA tumor virus. Some 200 million people are infected with hepatitis B virus, 10 million are infected with HIV-1, and an un


POSITIVE AND NEGATIVE REGULATION OF HUMAN T-CELL LEUKEMIA VIRUS TYPE I (HTLV-I) GENE EXPRESSION AND REPLICATION: FUNCTION OF THE REX GENE
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 3-20, 1991.. Unique Identifier : AIDSLINE ICDB/92678719
Yoshida M; Inoue J; Fujisawa J; Dept. of Cellular and Molecular Biology, Inst. of Medical; Science, Univ. of Tokyo, Tokyo 108, Japan
HTLV-I is a retrovirus, but is classified in a unique group distinct from the general onco-retroviruses. The genome contains an extra sequence named pX in addition to the gag, pol, and env genes. The Px region contains three overlapping genes, tax, rex, and a third that codes for p21, whose function is not yet known


HUMAN T-CELL LEUKEMIA VIRUS TYPE II
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 21-33, 1991.. Unique Identifier : AIDSLINE ICDB/92678720
Chen IS; Rosenblatt JD; Dept. of Medicine, Univ. of California, Los Angeles, CA 90024
Since its discovery in 1982, human T-cell leukemia virus type II (HTLV-II) has been a virus for which both diseases and its origin have been sought. It is associated with rare forms of human leukemia and may be the cause of hairy cell leukemia. HTLV-II is reviewed, including discovery and epidemiology; evidence for th


HUMAN IMMUNODEFICIENCY VIRUS (HIV) GENE STRUCTURE AND GENETIC DIVERSITY
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 35-67, 1991.. Unique Identifier : AIDSLINE ICDB/92678721
Klotman ME; Wong-Staal F; Lab. of Tumor Cell Biology, NCI, Bethesda, MD 20892
HIV-1 and HIV-2 are highly related in their genetic, morphologic, and biologic properties, and they must have diverged recently from a common progenitor. Similar viruses also have been identified in a number of simian species. The genetics of HIV-1 and HIV-2 is reviewed, with emphasis on information obtained from stud


HUMAN IMMUNODEFICIENCY VIRUS (HIV) GENE EXPRESSION AND FUNCTION
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 69-106, 1991.. Unique Identifier : AIDSLINE ICDB/92678722
Haseltine WA; Dana-Farber Cancer Inst., Harvard Medical Sch., Boston, MA 02115
The molecular biology of HIV-1 and related human and nonhuman primate retroviruses provides a basis for understanding the peculiar pathogenesis of AIDS. Beyond the immediate practical application of the study of the molecular biology of these viruses, their study has revealed new fundamental principles regarding the m


BIOLOGY OF HUMAN T-CELL LEUKEMIA VIRUS (HTLV) INFECTION
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 109-25, 1991.. Unique Identifier : AIDSLINE ICDB/92678723
Miyoshi I; Dept. of Medicine, Kochi Medical Sch., Kochi 783, Japan
Since the first discovery of murine leukemia virus, RNA tumor viruses (retroviruses) have been implicated in the etiology of many naturally-occurring leukemias and lymphomas in various animal species. Extensive studies have confirmed the etiological role of HTLV-I in adult T-cell leukemia (ATL); HTLV-I also has been l


RECEPTORS FOR HUMAN RETROVIRUSES
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 127-39, 1991.. Unique Identifier : AIDSLINE ICDB/92678724
Weiss RA; Inst. of Cancer Res., Royal Cancer Hosp., London SW3 6JB, UK
Retroviruses bind to cell surface receptors via their outer envelope glycoproteins, known as SU proteins. Following binding, membrane fusion probably is effected by a hydrophobic region of the transmembrane envelope protein. Fusion of many retroviruses takes place at neutral pH and is reflected by the capacity of the


IMMUNOPATHOLOGIC MECHANISMS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 141-61, 1991.. Unique Identifier : AIDSLINE ICDB/92678725
Rosenberg ZF; Fauci AS; Natl. Inst. of Allergy and Infectious Diseases, NIH, Bethesda, MD; 20892
The most striking feature of infection with HIV in vivo is a dramatic reduction in the number of T4 cells, a specific subset of helper/inducer T lymphocytes that expresses the CD4 antigen. The ultimate destruction of the T4 cell population results in a critical immune deficiency that permits the development of a wide


HUMAN T-CELL LEUKEMIA VIRUS (HTLV) INFECTION: A CLINICAL PERSPECTIVE
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 163-71, 1991.. Unique Identifier : AIDSLINE ICDB/92678726
Takatsuki K; Second Dept. of Internal Medicine, Kumamoto Univ. Medical Sch.,; Kumamoto 860, Japan
Adult T-cell leukemia/lymphoma (ATL) was the first human cancer found to be caused by a retrovirus. The advances made in the worldwide study of AIDS owe much to the knowledge gained about the relation between ATL and HTLV-I. For example, methods of isolation almost identical to those used for HTLV-I were used for isol


HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTIONS IN THE UNITED STATES
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 193-211, 1991.. Unique Identifier : AIDSLINE ICDB/92678728
Greenspan AL; Berkelman RL; Dondero TJ Jr; Curran JW; Div. of HIV/AIDS, Center for Infectious Diseases, CDC, Atlanta,; GA 30333
Since 1981, the natural history and modes of transmission of HIV have been illuminated by the availability of results from epidemiologic studies carried out in the United States and elsewhere. Ongoing analysis of reported United States AIDS cases since 1981 has yielded valuable informa


ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS): AN INTERNATIONAL PERSPECTIVE
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 213-24, 1991.. Unique Identifier : AIDSLINE ICDB/92678729
Sato PA; Chin J; Mann JM; Global Programme on AIDS, WHO, 1211 Geneva 27, Switzerland
The worldwide scope of HIV infection and AIDS did not become fully apparent until the middle of the 1980s, by which time HIV had spread across several continents. The global epidemiology of HIV/AIDS at the end of the 1980s is described, as well as the potential evolution of the pandemic in the 1990s and the global res


HUMAN T-CELL LEUKEMIA VIRUS TYPE I (HTLV-I): STUDIES OF DISEASE MECHANISMS IN A TRANSGENIC MOUSE SYSTEM
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 227-43, 1991.. Unique Identifier : AIDSLINE ICDB/92678730
Hinrichs SH; Chen L; Fontes J; Jay G; Dept. of Medical Pathology, Sch. of Medicine, Univ. of; California, Davis, CA 95616
HTLV-I has been associated with a wide range of human disease including adult T-cell leukemia (ATL), tropical spastic paraparesis, polymyositis, and possibly multiple sclerosis. Results obtained using a transgenic mouse experimental system are reviewed, including current problems and molecular considerations; value of


TRANSGENIC MOUSE MODEL OF HUMAN IMMUNODEFICIENCY VIRUS (HIV)-INDUCED KAPOSI'S SARCOMA
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 277-94, 1991.. Unique Identifier : AIDSLINE ICDB/92678731
Vogel J; Rhim JA; Jay DB; Jay G; Jerome H. Holland Lab., American Red Cross, Rockville, MD 20855
In the study of HIV, an alternative to finding animals that can be successfully infected with HIV is to derive animal models by placing the viral genome or segments of it directly into the germline of animals. One such model has been developed by microinjecting a chimeric construct containing the HIV tat gene under th


THE SCID-HU MOUSE AS A MODEL FOR HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 295-316, 1991.. Unique Identifier : AIDSLINE ICDB/92678732
Mc Cune JM; SyStemix, Inc., Palo Alto, CA 94303
A major obstacle to research on the role of HIV in AIDS has been the lack of an adequate model for HIV infection. An optimal model would be one in which HIV can be observed to infect human hematolymphoid organ systems within the confines of a mouse. Such a model has been developed in the form of the SCID-hu mouse. The


ADULT T-CELL LEUKEMIA: PROSPECTS FOR IMMUNOTHERAPY
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 319-32, 1991.. Unique Identifier : AIDSLINE ICDB/92678733
Waldmann TA; Metabolism Branch, NCI, Bethesda, MD 20892
Immune intervention is playing an increasing role in therapy, but the potential provided by the great specificity of the human immune system clearly has not been achieved. Interleukin-2 receptor (IL-2R) has been employed as a target for immune intervention in patients with adult T-cell leukemia (ATL). The prospects fo


TOWARD THE RATIONAL DESIGN OF ANTIRETROVIRAL THERAPY FOR HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 335-78, 1991.. Unique Identifier : AIDSLINE ICDB/92678734
Mitsuya H; Broder S; Clinical Oncology Program, NCI, Bethesda, MD 20892
Replication of HIV can be suppressed in patients with HIV-related diseases by several antiretroviral agents. One such drug, 3 -azido-2 ,3 -dideoxynucleoside ( AZT or zidovudine), has been formally shown to confer prolonged survival and improved quality


CD4-PE40: A CHIMERIC TOXIN ACTIVE AGAINST HUMAN IMMUNODEFICIENCY VIRUS (HIV)-INFECTED CELLS
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 379-87, 1991.. Unique Identifier : AIDSLINE ICDB/92678735
Chaudhary VK; Moss B; Berger EA; FitzGerald DJ; Pastan I; Lab. of Molecular Biology, NCI, Bethesda, MD 20892
The realization that HIV uses CD4 on the surface of T cells as its receptor, and later in its life cycle expresses gp120 (envelope glycoprotein) on the cell surface, has permitted the design of therapies to kill HIV-infected cells to interrupt the life cycle of the virus. To accomplish this task, a novel toxin molecul


VACCINES AGAINST ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS)
The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 389-405, 1991.. Unique Identifier : AIDSLINE ICDB/92678736
Bolognesi DP; Center for AIDS Res., Duke Univ. Medical Center, Durham, NC 27710
The science of vaccinology has been mainly empirical, being based largely on trial and error using various formulations of the disease-causing organism itself. However, a vaccine against the AIDS virus will depend heavily on the depth of knowledge of HIV/host interactions at the molecular level and the use of technolo


Practical reasoning in medicine and the rise of clinical ethics.
J Clin Ethics. 1990 Fall;1(3):187-92; discussion 193-4. Unique Identifier : AIDSLINE MED/92063179
Rodeheffer JK; St. Mary's College of Minnesota.
Infection control in pediatric dentistry--considerations and procedures.
Update Pediatr Dent. 1990 Apr;3(2):1-4, 6-8. Unique Identifier : AIDSLINE MED/92068346
Leggott PJ; Walker PO; Division of Pediatric Dentistry, University of British Columbia.
T-lymphocyte subpopulations in pregnant women with newly diagnosed type 1 diabetes.
Diabetes Res. 1990 Aug;14(4):187-90. Unique Identifier : AIDSLINE MED/92070024
Buschard K; Kuhl C; Molsted-Pedersen L; Ropke C; Bartholin Institute, Kommunehospitalet, Copenhagen, Denmark.
The thymus-dependent immune system is involved in the disease process underlying Type 1 diabetes. Several studies have thus shown the distribution of peripheral T-lymphocyte subsets to be altered in diabetics. Unlike many other autoimmune diseases which improve during pregnancy, Type 1 diabetes has a higher incidence


Oral candidiasis: an old disease of growing concern.
Gen Dent. 1990 Mar-Apr;38(2):114-20. Unique Identifier : AIDSLINE MED/92070696
Reichl RB; U.S. Army Dental Corps.
Knowledge, attitudes and practices on the acquired immune deficiency syndrome (AIDS) among health workers in (Nyeri) a district in Kenya.
Kenya Nurs J. 1990 Jun;18(1):28-30. Unique Identifier : AIDSLINE MED/92072197
Karani A; Katsivo K; Muhami LN; Lwafama DW; Ntsekhe
OBJECTIVE: To assess the level of knowledge, Attitudes and practices of health workers toward HIV/AIDS. METHOD: The study was a cross-sectional KAP study of HIV/AIDS among 263 health workers in a district in Kenya . A self administered questionnaire was completed by the health worker


[Acquired immunodeficiency syndrome in pediatric patients]
Pract Odontol. 1990 Dec;11(12):31, 34, 36-7. Unique Identifier : AIDSLINE MED/92080484
Molina Moguel JL; Ruiz Illezcas R; Forsbach Sanchez S; Carreno Alvarez S; Picco Diaz I; Hospital Regional 20 de Noviembre, ISSSTE.
The object of this study was to determine how many of the patients treated at the Pediatric Odontology Clinic, a branch of the Maxillo-Facial Surgery Service at the Veinte de Noviembre Regional Hospital, ISSSTE, are VIH-positive of show serious manifestations of Acquired Immuno-Deficiency Syndrome (AIDS). For such pur


AIDS--your responsibility and your source of help [editorial]
GMDA Bull. 1990 Dec;57(4):121. Unique Identifier : AIDSLINE MED/92070734
Johnson R; Keever E
Treating AIDS patients--not just the right thing, but the only safe thing to do [editorial]
GMDA Bull. 1990 Dec;57(4):125-6. Unique Identifier : AIDSLINE MED/92070735
Johnson R
[Clinical evaluation of the use of teicoplanin for staphylococcal infections in immunocompetent and immunodepressed patients]
Riv Eur Sci Med Farmacol. 1990 Dec;12(6):319-24. Unique Identifier : AIDSLINE MED/92073621
Catania S; Trinchieri V; Lanzalone CM; Causo T; Allegra C; Catania N; Cirelli A; Istituto Malattie Infettive, Universita La Sapienza, Roma.
The authors have evaluated the efficacy and tolerance of teicoplanin against Gram-positive infections in 8 patients (four with endocarditis, one with cholangitis, one with purulent arthritis, one with gathered fistula and one with general pyoderma), arose both in the immunocompetent and immunodepressed subjects. All p


[Importance of hairy leukoplakia and AIDS to the dentist. (Review of the literature)]
Pract Odontol. 1990 Oct;11(10):43-8. Unique Identifier : AIDSLINE MED/92080469
Ledesma Montes C; Leyva Huerta ER; Universidad Nacional Autonoma de Mexico.
AIDS is currently one of the most important and concerning diseases for dentists, both general and specialized. This review of the literature makes emphasis on the main biological, epidemiological, diagnostic and prognostic aspects of oral hairy leucoplakia which every dental care professionist should know, as well as


Evidence for susceptibility of intrathymic T cell precursors to human immunodeficiency virus infection: a mechanism for T4 (CD4) lymphocyte depletion.
Trans Assoc Am Physicians. 1990;103:96-101. Unique Identifier : AIDSLINE MED/92087383
Schnittman SM; Denning SM; Greenhouse JJ; Justement JS; Baseler M; Haynes BF; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.
Global projections for the year 2000 [news]
World Health Forum. 1991;12(2):242. Unique Identifier : AIDSLINE MED/92062300
World AIDS Day 1991 [news]
World Health Forum. 1991;12(2):242-3. Unique Identifier : AIDSLINE MED/92062301
Detection of anti-HIV antibodies in immunoglobulin preparations: the significance of antibodies to the HIV-envelope.
Biologicals. 1991 Jul;19(3):197-202. Unique Identifier : AIDSLINE MED/92062366
Gentili G; Wirz M; Puccinelli M; Mele C; Collotti C; Vicari G; Laboratorio di Immunologia, Istituto Superiore di Sanita, Rome,; Italy.
Four hundred and sixty-eight immunoglobulin preparations, produced between 1969 and 1989, were examined for anti-HIV antibodies by means of two competitive immunoenzymatic assays and the Western blot test. This study refers the results obtained by the three different methods. Such results show that the detection of an


Syphilis maligna: a HIV-related problem?
Br J Dermatol. 1991 Oct;125(4):390-1. Unique Identifier : AIDSLINE MED/92062561
De Rie MA; Mekkes JR; Cohen EB; Hulsebosch HJ; Department of Dermatology, University of Amsterdam, Amsterdam.
Bacillary angiomatosis.
Br J Dermatol. 1991 Oct;125(4):393-4. Unique Identifier : AIDSLINE MED/92062564
Cairo I; Hulsebosch HJ; Van Der Wouw PA; Departments of Dermatology and Internal Medicine, University of; Amsterdam.
Epidemic Kaposi's sarcoma in Italy, a country with intravenous drug users as the main group affected by HIV infection.
Ann Oncol. 1991 May;2(5):373-6. Unique Identifier : AIDSLINE MED/92062626
Tirelli U; Vaccher E; Lazzarin A; Errante D; Alessi E; Crosato I; Spina M; Zaccarelli M; Aiuti F; Moroni M; et al; Centro Regionale di Riferimento Oncologico, Aviano, Italy.
The Italian Cooperative Group on AIDS & Tumors (GICAT) is collecting data on the epidemiological and clinical features of Kaposi s sarcoma (KS) in Italy , a country where intravenous drug users (IVDUs) comprise the largest group affected by AIDS. As of December 31st 1989, among 5317


Cytidine diphosphate diglyceride analogs of antiretroviral dideoxynucleosides: evidence for release of dideoxynucleoside-monophosphates by phospholipid biosynthetic enzymes in rat liver subcellular fractions.
Biochim Biophys Acta. 1991 Oct 15;1086(1):99-105. Unique Identifier : AIDSLINE MED/92062726
van Wijk GM; Hostetler KY; Schlame M; van den Bosch H; Centre for Biomembranes and Lipid Enzymology, University of; Utrecht, The Netherlands.
We recently synthesized phospholipid analogs with antiviral nucleosides in the polar headgroup and demonstrated their antiretroviral activity in vitro in human immunodeficiency virus-infected cells (Hostetler, K.Y., Stuhmiller, L.M., Lenting, H.B.M., van den Bosch, H. and Richman, D.D. (1990) J. Biol. Chem. 265, 6112-


[Pneumococcal pneumonia and HIV (editorial)]
Enferm Infecc Microbiol Clin. 1991 May;9(5):263-4. Unique Identifier : AIDSLINE MED/92062739
Moreno S; Garcia-Leoni ME
[Bacteremia caused by Streptococcus pneumoniae and HIV infection]
Enferm Infecc Microbiol Clin. 1991 May;9(5):268-71. Unique Identifier : AIDSLINE MED/92062741
Roca V; Perez-Cecilia E; Vinuelas J; Ferreiros J; Coello R; Picazo JJ; Departamento de Medicina Interna, Hospital Clinico Universitario; San Carlos, Madrid.
We analyze seven patients with HIV infection that developed community-acquired bacteremic pneumonia due to Streptococcus pneumoniae. Six patients were drug addicts and one was a male homosexual. Five patients have been previously diagnosed of having AIDS. All patients had fever with respiratory tract symptoms and abno


[HTLV-I infection in sailors who travel to sub-Saharan West Africa]
Enferm Infecc Microbiol Clin. 1991 May;9(5):283-5. Unique Identifier : AIDSLINE MED/92062744
Pujol E; Ollero M; Marquez P; Gea A; Alcoucer R; Gimeno A; Servicios de Medicina Interna, Hospital General, Huelva.
In order to assess if HTLV-1 retrovirus had penetrated in a group of sailors that often travel to endemic areas for HTLV-1 infection (West coast of sub-Saharan Africa) we have performed the following study. A total of 499 sera samples from sailors traveling to Africa during the last five years were studied. The presen


[Bacterial infections in patients with acquired immunodeficiency syndrome]
Enferm Infecc Microbiol Clin. 1991 May;9(5):297-307. Unique Identifier : AIDSLINE MED/92062748
Reparaz J; Unidad de Enfermedades Infecciosas, Hospital de Navarra,; Pamplona.
Chronic infections and autoimmunity.
Immunol Ser. 1991;55:285-313. Unique Identifier : AIDSLINE MED/92062776
Abu-Shakra M; Shoenfeld Y; Soroka Medical Center, Beer-Sheva, Israel.
The studies summarized in this chapter indicate that chronic bacterial, viral, and parasitic infections can serve as a trigger factor of autoimmune reactivity according to various mechanisms. The relationship between microbes and autoimmunity could be manifested by the presence of autoantibodies, autoimmune complexes,


AIDS vaccine making strides [news]
J ET Nurs. 1991 Nov-Dec;18(6):50A. Unique Identifier : AIDSLINE MED/92062798
Immunological and virological status of a hemophiliac infected with human T cell lymphotropic virus type 1 and human immunodeficiency virus type 1, and results of therapy.
Int J Hematol. 1991 Feb;54(1):85-90. Unique Identifier : AIDSLINE MED/92062983
Murakami T; Hattori T; Maeda Y; Matsushita S; Kannagi M; Sagawa K; Takatsuki K; Second Department of Internal Medicine, Kumamoto University; Medical School, Japan.
The immunological and virological status of three hemophiliacs infected with human immunodeficiency virus type 1 (HIV-1) was monitored for 11 months. One of these patients was also infected with human T cell lymphotropic virus type 1 (HTLV-1), and HIV-1 could be isolated only from this patient among the three subjects


[Computed tomography of disseminated extrapulmonary Pneumocystis carinii infection]
Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1991 Nov;155(5):474-5. Unique Identifier : AIDSLINE MED/92062999
Gaa J; Strahleninstitut der Stadtischen Kliniken Darmstadt.
Formation of a new social group of unfamiliar female rhesus monkeys affects the immune and pituitary adrenocortical systems.
Brain Behav Immun. 1991 Sep;5(3):296-307. Unique Identifier : AIDSLINE MED/92063220
Gust DA; Gordon TP; Wilson ME; Ahmed-Ansari A; Brodie AR; McClure HM; Yerkes Regional Primate Research Center, Atlanta, Georgia.
Social stress associated with the formation of a new group of rhesus monkeys resulted in increased basal cortisol secretion and significant decreases in immunological parameters. Eight adult female rhesus monkeys, all of which had been raised in social groups, but with no common social history, were simultaneously int


Zidovudine after occupational exposure to HIV [letter; comment] [see comments]
BMJ. 1991 Oct 19;303(6808):990. Unique Identifier : AIDSLINE MED/92063252
Brown EM; Caul EO; Roome AP; Glover SC; Reeves DS; Harling CC
The health of the nation: responses. Injecting drug misuse.
BMJ. 1991 Oct 26;303(6809):1043-6. Unique Identifier : AIDSLINE MED/92063288
Strang J; Drug Dependence Clinical Research and Treatment Unit, Bethlem; Royal Hospital, Beckenham.
Imported HIV infection acquired heterosexually [letter]
BMJ. 1991 Oct 26;303(6809):1060-1. Unique Identifier : AIDSLINE MED/92063298
Ainsworth JG; Murphy SM; Harris JR
Vaccines for HIV infected pregnant women? [letter; comment]
BMJ. 1991 Oct 26;303(6809):1061. Unique Identifier : AIDSLINE MED/92063300
Nixon D
25 years of gynaecology.
Br J Hosp Med. 1991 Oct;46(4):230, 233. Unique Identifier : AIDSLINE MED/92063323
Studd J; King's College Hospital, London.
Needlestick injuries [news]
Can Nurse. 1991 Sep;87(8):15. Unique Identifier : AIDSLINE MED/92063485
Remkes T
HIV detection in newborns [news]
Can Nurse. 1991 Oct;87(9):11-2. Unique Identifier : AIDSLINE MED/92063497
AIDS consultations a success [news]
Can Nurse. 1991 Oct;87(9):4-5. Unique Identifier : AIDSLINE MED/92063508
A strong inhibition of HIV-induced cytopathic effects by synthetic (1----6)-alpha-D-mannopyranan sulfate.
Carbohydr Res. 1991 Jul 18;214(1):147-54. Unique Identifier : AIDSLINE MED/92063516
Hatanaka K; Kurihara Y; Uryu T; Yoshida O; Yamamoto N; Mimura T; Kaneko Y; Institute of Industrial Science, University of Tokyo, Japan.
The anti-HIV effects of mannopyranan sulfate (1) were investigated by using MT-4 cells, namely, an HTLV-I-carrying CD-4 positive cell-line, in vitro. Stereoregular (1----6)-alpha-D-mannopyranan, which had been synthesized by ring-opening polymerization of a 1,6-anhydromannose derivative, was sulfated with piperidine-N


Osteoarticular infection associated with the human immunodeficiency virus.
Clin Exp Rheumatol. 1991 Sep-Oct;9(5):489-93. Unique Identifier : AIDSLINE MED/92063617
Munoz Fernandez S; Quiralte J; del Arco A; Balsa A; Cardenal A; Pena JM; Vazquez JJ; Gijon Banos J; Rheumatology Unit, Hospital La Paz, Universidad Autonoma de; Madrid, Spain.
An analysis is presented of 20 patients with the human immunodeficiency virus (HIV) infection who were treated for skeletal infection in our hospital. Seventeen cases of septic arthritis and three of osteomyelitis were found. All patients were intravenous drug abusers, 75% were male and all were younger than 40 years


Iron and lymphocytes: reciprocal regulatory interactions.
Curr Stud Hematol Blood Transfus. 1991;(58):171-7. Unique Identifier : AIDSLINE MED/92063703
de Sousa M; Reimao R; Porto G; Grady RW; Hilgartner MW; Giardina P; Abel Salazar Institute for the Biomedical Sciences, Oporto,; Portugal.
Clotting factors isolated with monoclonal antibodies.
Curr Stud Hematol Blood Transfus. 1991;(58):52-8. Unique Identifier : AIDSLINE MED/92063716
Gomperts ED; Children's Hospital, Los Angeles, Calif.
Cerebrospinal fluid pleocytosis in aseptic meningitis: cytomorphic and immunocytochemical features.
Diagn Cytopathol. 1991;7(5):532-5. Unique Identifier : AIDSLINE MED/92063794
Ross JS; Magro C; Szyfelbein W; Sorensen S; James Homer Wright Pathology Laboratories, Massachusetts General; Hospital, Boston.
We report five cases of aseptic meningitis presenting with high cerebrospinal fluid (CSF) cell counts (260-600 cells/cmm) and mononuclear pleocytosis, suggesting the diagnosis of CNS malignant lymphoma. In four of five cases a reactive background of small lymphocytes, monocytes, and eosinophils was seen. Immunocytoche


Occurrence of Pneumocystis carinii organisms in a peritoneal effusion from a patient with the acquired immunodeficiency syndrome.
Diagn Cytopathol. 1991;7(5):540-2. Unique Identifier : AIDSLINE MED/92063796
Magliocco A; Miller K; Robertson DI; Gill MJ; Department of Pathology, Foothills Hospital, Calgary, Alberta,; Canada.
We describe a unique case of Pneumocystis carinii organisms within a peritoneal effusion of a patient with acquired immunodeficiency syndrome (AIDS). The patient, a 28-yr-old homosexual male with profound immunosuppression, presented with splenomegaly and ascites. A peritoneal tap was performed for diagnostic purposes


AIDS-related safety issues for the cytology laboratory.
Diagn Cytopathol. 1991;7(5):543-5. Unique Identifier : AIDSLINE MED/92063797
Cohen MB; Zaleski MS; Wenzel RP; Department of Pathology, University of Iowa, Iowa City 52242.
Ethical issues: nursing and HIV/AIDS.
Fla Nurse. 1991 May;39(5):9. Unique Identifier : AIDSLINE MED/92064061
Denker AL
Avoiding occupational exposure to HIV.
Fla Nurse. 1991 Oct;39(9):15. Unique Identifier : AIDSLINE MED/92064064
Montejo M
Update on AHCPR: Agency for Health Care Policy & Research.
Fla Nurse. 1991 Oct;39(9):4, 6. Unique Identifier : AIDSLINE MED/92064069
Nursing and human immunodeficiency.
Fla Nurse. 1991 Oct;39(9):9, 12. Unique Identifier : AIDSLINE MED/92064071
Severe chronic active hepatitis (autoimmune type) mimicked by coinfection of hepatitis C and human immunodeficiency viruses.
Gut. 1991 Oct;32(10):1198-200. Unique Identifier : AIDSLINE MED/92064262
Berk L; Schalm SW; Heijtink RA; Department of Internal Medicine II, University Hospital Dijkzigt,; Rotterdam, The Netherlands.
Severe chronic active hepatitis, defined as the presence of a fivefold increase in serum aminotransferases and a twofold rise in gamma globulin for at least 10 weeks, is considered a progressive immunological liver disease requiring corticosteroid treatment, particularly when serum autoantibodies and a severe lymphopl


Recent trends in the incidence of salivary gland cancer.
Int J Epidemiol. 1991 Sep;20(3):628-33. Unique Identifier : AIDSLINE MED/92064366
Horn-Ross PL; West DW; Brown SR; Northern California Cancer Center, Alameda, CA 94501.
Beginning in 1985, a sudden and sustained doubling of salivary gland cancer incidence, among men only, is observed in the San Francisco-Oakland Metropolitan Statistical Area. Registry data are examined to determine the nature of this increase and its possible association with the AIDS epidemic. Changes in patient char


Risk factors for HIV infection in adults attending sexually transmitted disease clinics in Italy.
Int J Epidemiol. 1991 Sep;20(3):758-63. Unique Identifier : AIDSLINE MED/92064382
Parazzini F; Naldi L; Sena P; Cavalieri d'Oro L; Bianchi C; Manganoni A; Pansera B; Gramenzi A; Goglio A; Cainelli T; Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
We assessed prevalence and risk factors for human immunodeficiency virus (HIV) infection in 637 patients (506 men, 131 women; median age 30 years, range 17-64) attending between September 1988 and July 1989 for the first time two sexually transmitted disease (STD) clinics in Northern It


Guidelines for nursing management of people infected with human immunodeficiency virus (HIV)--W.H.O.
Ir Nurs News. 1991 Autumn;12(1):2, 5. Unique Identifier : AIDSLINE MED/92064428
Non-Hodgkin lymphomas of the central nervous system.
Ital J Neurol Sci. 1991 Oct;12(5):453-9. Unique Identifier : AIDSLINE MED/92064433
Pisani F; Antimi M; Cantonetti M; Marciani MG; Masi M; Tribalto M; Papa G; Cattedra di Ematologia, Universita Tor Vergata, Roma.
Non-Hodgkin lymphomas (NHL) of the Central Nervous System (CNS) are rare but they nonetheless constitute a clinical, biological and therapeutic problem of great interest. Primary lymphomas of the CNS account for 2% of all malignant lymphomas and for 0.3-1.5% of all intracranial tumors. Surgery and radiotherapy afford


The prevalence and interaction of human immunodeficiency virus and hepatitis B virus infections in Israeli hemophiliacs [see comments]
Isr J Med Sci. 1991 Oct;27(10):557-61. Unique Identifier : AIDSLINE MED/92064441
Brenner B; Schwartz S; Ben-Porath E; Tatarsky I; Varon D; Martinowitz U; Hematology Institute, Rambam Medical Center, Haifa, Israel.
The prevalence, clinical manifestations and serological markers of hepatitis B virus (HBV) and human immunodeficiency (HIV) infections were studied in 117 Israeli hemophiliacs. Positive serological markers for HBV infection (HB surface antigen, antibody to HB surface antigen or antibody to HB core antigen) were more c


Hemophilia and the human immunodeficiency virus [editorial; comment]
Isr J Med Sci. 1991 Oct;27(10):572-4. Unique Identifier : AIDSLINE MED/92064444
Slater PE
Tuberculosis and AIDS.
Isr J Med Sci. 1991 Oct;27(10):576-7. Unique Identifier : AIDSLINE MED/92064446
Maayan S; Meiner V; Englehard D; Department of Clinical Microbiology, Hadassah University; Hospital, Jerusalem, Israel.
An efficient and simple method of DNA extraction from whole blood and cell lines to identify infectious agents.
J Virol Methods. 1991 Sep;34(1):105-12. Unique Identifier : AIDSLINE MED/92064686
Loparev VN; Cartas MA; Monken CE; Velpandi A; Srinivasan A; Wistar Institute of Anatomy and Biology, Philadelphia,; Pennsylvania 19104.
Routine methods of extraction of DNA from blood involve the enrichment of cells by Ficoll-Hypaque gradient centrifugation followed by lysis of the cells with extraction buffer, proteinase K digestion of the lysate, and phenol:chloroform-isoamyl alcohol extraction. These methods generally require large amounts of blood


A comparison of four enzyme immunoassays for the simultaneous detection of HIV-1- and HIV-2-specific antibody.
J Virol Methods. 1991 Sep;34(1):91-100. Unique Identifier : AIDSLINE MED/92064694
Berry NJ; Salker R; Contreras M; Barbara JA; Tedder RS; Department of Medical Microbiology, University College and; Middlesex School of Medicine, London, U.K.
The performance of four HIV 1 and 2 combined assays has been compared with current type-specific assays using three panels of sera. The first panel comprised single samples from 19 HIV-1-infected persons; the second panel comprised 19 sera from 16 HIV-2-infected persons. Samples from both these panels were titrated ac


Metacognition in HIV-1 seropositive asymptomatic individuals: self-ratings versus objective neuropsychological performance. Multicenter AIDS Cohort Study (MACS).
J Clin Exp Neuropsychol. 1991 Sep;13(5):812-9. Unique Identifier : AIDSLINE MED/92064742
van Gorp WG; Satz P; Hinkin C; Selnes O; Miller EN; McArthur J; Cohen B; Paz D; Department of Veteran's Affairs Medical Center West Los Angeles,; CA 90073.
This study examined the relationship between actual and self-reported neuropsychological deficits, depression, and HIV-1 serostatus. The subjects, who consisted of 479 individuals, 256 who were HIV seronegative (SN) and 233 who were HIV-1 seropositive though still asymptomatic (ASP), were administered a standardized n


Elevated antibodies to synthetic peptides of HTLV-1 envelope transmembrane glycoproteins in patients with HAM/TSP.
J Neuroimmunol. 1991 Dec;35(1-3):167-77. Unique Identifier : AIDSLINE MED/92064781
Nakamura M; Kuroki M; Kira J; Itoyama Y; Shiraki H; Kuroda N; Washitani Y; Nakano S; Nagafuchi S; Anzai K; et al; First Department of Internal Medicine, Faculty of Medicine,; Kyushu University, Fukuoka, Japan.
We studied the antibody response to various kinds of well-characterized synthetic peptides of human T lymphotropic virus type 1 (HTLV-1) envelope glycoproteins in patients with HTLV-1 associated myelopathy (HAM)/tropical spastic paraparesis (TSP) and non-HAM/TSP HTLV-1 carriers. The serum antibody titers to most of th


Intrathecal synthesis of IgG subclasses in multiple sclerosis and in acquired immunodeficiency syndrome (AIDS).
J Neuroimmunol. 1991 Dec;35(1-3):179-89. Unique Identifier : AIDSLINE MED/92064782
Lambin P; Gervais A; Levy M; Defendini E; Dubarry M; Lebon P; Rouger P; Schuller E; Laboratoire d'Immunochimie, Institut National de la Transfusion,; Sanguine, Paris, France.
Serum and cerebrospinal fluid (CSF) of 50 neurological patients (24 multiple sclerosis (MS), ten acquired immunodeficiency syndrome (AIDS) and 16 other neurological diseases (OND)) and ten controls were analyzed by enzyme-linked immunosorbent assay (ELISA) for IgG subclass quantification and for the calculation of int


Soluble CD4 and CD8 in the peripheral blood of patients with multiple sclerosis and HTLV-1-associated myelopathy.
J Neuroimmunol. 1991 Dec;35(1-3):285-93. Unique Identifier : AIDSLINE MED/92064793
Tsukada N; Matsuda M; Miyagi K; Yanagisawa N; Department of Neurology, Shinshu University, School of Medicine.
We evaluated the presence of soluble (s) CD4 and sCD8, released from activated T cells, in the sera of patients with multiple sclerosis (MS) and human T lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM) using an enzyme-linked immunosorbent assay (ELISA). In addition, peripheral blood T cell subsets in pat


Increased occurrence of free immunoglobulin light chains in cerebrospinal fluid and serum in human immunodeficiency virus-1 infection.
J Neuroimmunol. 1991 Dec;35(1-3):65-77. Unique Identifier : AIDSLINE MED/92064798
Elovaara I; Seppala I; Kinnunen E; Laaksovirta H; Department of Microbiology, Aurora Hospital, Helsinki, Finland.
The presence of free immunoglobulin light chains (FLCs) in the cerebrospinal fluid (CSF) and sera of patients with human immunodeficiency virus-1 (HIV-1) infection, multiple sclerosis (MS), and neurologically healthy control individuals was investigated by paying special attention to ensure that only truly free light


A psychoeducational model for changing nurses' AIDS knowledge, attitudes, and practices.
J Contin Educ Nurs. 1991 Nov-Dec;22(6):237-44. Unique Identifier : AIDSLINE MED/92064827
Flaskerud JH
A review of the research literature over the last five years reveals that nurses knowledge of the human immunodeficiency virus (HIV) has improved dramatically. However, attitudes and fears about HIV and acquired immunodeficiency syndrome (AIDS) have not changed commensurately with nurses knowledge. Also, there is ev


Detection of human IgE to sulfamethoxazole by skin testing with sulfamethoxazoyl-poly-L-tyrosine.
J Allergy Clin Immunol. 1991 Nov;88(5):784-92. Unique Identifier : AIDSLINE MED/92064882
Gruchalla RS; Sullivan TJ; Southwestern Medical Center, Dallas, Texas 75235-8859.
Adverse reactions to sulfamethoxazole (SMX) occur in 4% to 6% of normal individuals. Many of these reactions resemble immunopathologic reactions, but skin test or in vitro evidence of a role for IgE is limited. Earlier RAST studies in our laboratory provided evidence that the N4-SMX hapten was a major determinant in i


Surveillance for HIV antibody and antigen in trauma patients.
J Emerg Med. 1991;9 Suppl 1:1-3. Unique Identifier : AIDSLINE MED/92064926
Orr MD; Hoos A; Riester DE; Gilcher RO; Meltz ML; Department of Anesthesiology, University of Texas Health Science; Center, San Antonio 78284-7838.
Studies in a Baltimore emergency room identified the patient with penetrating trauma as having the highest incidence of Human Immunodeficiency Virus Type I (HIV-1) infection. Anonymous testing over a 15-month period of 165 victims of penetrating trauma presenting to the Medical Center Hospital Emergency Center (San An


Bacterial pneumonia in the HIV-infected patient.
Infect Dis Clin North Am. 1991 Sep;5(3):485-507. Unique Identifier : AIDSLINE MED/92064965
Cohn DL; AIDS Services, Denver Department of Health and Hospitals,; Colorado.
The incidence of bacterial pneumonia is increased in human immunodeficiency virus (HIV) infection, and bacteremia and recurrences occur frequently. Streptococcus pneumoniae and Haemophilus influenzae are the most common pathogens, but several other organisms have now been identified as etiologies. Several abnormalitie


Pulmonary tuberculosis in the HIV-positive patients.
Infect Dis Clin North Am. 1991 Sep;5(3):623-33. Unique Identifier : AIDSLINE MED/92064972
Yamaguchi E; Reichman LB; Infectious Diseases Section, East Orange Veterans Administration; Medical Center, New Jersey.
Tuberculosis associated with human immunodeficiency virus (HIV) infection continues to represent a serious medical and public health problem. Physicians awareness of this entity is important because the diagnosis requires a high index of suspicion. A continuing increase in the cases of tuberculosis associated with HI


Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA [published erratum appears in J Infect Dis 1992 Jun;165(6):1161]
J Infect Dis. 1991 Dec;164(6):1051-7. Unique Identifier : AIDSLINE MED/92064979
Fox CH; Tenner-Racz K; Racz P; Firpo A; Pizzo PA; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda,; Maryland.
When radiolabeled RNA was used for in situ hybridization, human immunodeficiency virus type 1 (HIV-1) RNA was found in high concentrations in germinal centers of lymphoid tissues from patients with HIV-1 infection. Most of the signal from hybridized probe was independent of specific cells, being found in the extracell


Use of self-sustained sequence replication amplification reaction to analyze and detect mutations in zidovudine-resistant human immunodeficiency virus.
J Infect Dis. 1991 Dec;164(6):1066-74. Unique Identifier : AIDSLINE MED/92064981
Gingeras TR; Prodanovich P; Latimer T; Guatelli JC; Richman DD; Barringer KJ; Department of Pathology, University of California, San Diego.
Mutations at amino acid positions 67, 70, 215, and 219 in the human immunodeficiency virus type 1 (HIV-1) pol gene correlate with the emergence of resistance to zidovudine ( AZT ). These four positions were monitored in viral RNA extracted from infected


Immunoglobulin prophylaxis against milkborne transmission of human T cell leukemia virus type I in rabbits.
J Infect Dis. 1991 Dec;164(6):1193-6. Unique Identifier : AIDSLINE MED/92064999
Sawada T; Iwahara Y; Ishii K; Taguchi H; Hoshino H; Miyoshi I; Department of Medicine, Kochi Medical School, Japan.
Prophylactic effect of human T cell leukemia virus type I (HTLV-I) immune globulin (HTLVIG) against milkborne transmission of HTLV-I was investigated in a rabbit model. Four litters (A-D: 7, 5, 7, and 7 offspring, respectively) born to an HTLV-I-infected rabbit were used. Litters A and D were allowed to grow normally


Analytical methodology in a cohort study of cofactors for sexual transmission of human immunodeficiency virus [letter; comment]
J Infect Dis. 1991 Dec;164(6):1236-7. Unique Identifier : AIDSLINE MED/92065011
Roddy RE; Feldblum PJ
Resolution of hairy leukoplakia: an observational trial of zidovudine versus no treatment [letter]
J Infect Dis. 1991 Dec;164(6):1240-1. Unique Identifier : AIDSLINE MED/92065015
Katz MH; Greenspan D; Heinic GS; Chan AK; Hollander H; Chernoff D; Greenspan JS
Proinflammatory cytokines in intestinal mucosa.
Immunol Res. 1991;10(3-4):247-8. Unique Identifier : AIDSLINE MED/92065047
Reinecker HC; Steffen M; Doehn C; Petersen J; Pfluger I; Voss A; Raedler A; Department of Internal Medicine, University Hospital Eppendorf,; Hamburg, FRG.
Expression of human immunodeficiency virus-1 in human colonic cells.
Immunol Res. 1991;10(3-4):452-5. Unique Identifier : AIDSLINE MED/92065088
Kagnoff MF; Omary MB; de Grandpre LY; Roebuck KA; Richman DD; Brenner DA; Department of Medicine, University of California, San Diego, La; Jolla.
Balint's syndrome in subacute HIV encephalitis [see comments]
J Neurol Neurosurg Psychiatry. 1991 Sep;54(9):822-5. Unique Identifier : AIDSLINE MED/92065293
Schnider A; Landis T; Regard M; Department of Neurology, University Hospital, Zurich,; Switzerland.
A 45 year old patient with AIDS is described in whom Balint s syndrome developed over several days without other higher cognitive defects. Radiological findings were typical of subacute HIV encephalitis involving mainly the white matter of the occipital lobes with extension into the parietal and temporal lobe on the l


Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(- 1H)-on e (TIBO) derivatives. 2.
J Med Chem. 1991 Nov;34(11):3187-97. Unique Identifier : AIDSLINE MED/92065462
Kukla MJ; Breslin HJ; Diamond CJ; Grous PP; Ho CY; Miranda M; Rodgers JD; Sherrill RG; De Clercq E; Pauwels R; et al; Janssen Research Foundation, Spring House, Pennsylvania 19477.
In the first paper of this series a new structure with anti-HIV-1 activity was disclosed and analogues were synthesized to explore the structure-activity relationship of changes in the substituent (R) attached at the N-6 position of 9. This study describes the syntheses and anti-HIV-1 testing of analogues with variati


Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere.
J Med Chem. 1991 Nov;34(11):3340-2. Unique Identifier : AIDSLINE MED/92065483
Krohn A; Redshaw S; Ritchie JC; Graves BJ; Hatada MH; Roche Products Ltd., Welwyn Garden City, Hertfordshire, United; Kingdom.
Hematological indices in a cohort of HTLV-I/II and HIV-1 infected intravenous drug users in New York City.
J Natl Med Assoc. 1991 Aug;83(8):677-9. Unique Identifier : AIDSLINE MED/92065516
Brown LS Jr; Chu A; Lee H; Allain JP; Division of Medical Services, Addiction Research and Treatment; Corporation, Brooklyn, New York 11201.
The prevalence and clinical consequences of human T-cell lymphotropic viruses types I and II (HTLV-I/II) infection in human immunodeficiency virus-1 (HIV-1) infected persons are areas of continuing interest. This article reports the preliminary findings of the hematological indices in 454 patients infected with HIV-1


AIDS update. Condom availability in New York City schools.
J Sch Health. 1991 Aug;61(6):279-80. Unique Identifier : AIDSLINE MED/92065633
Kerr DL; American School Health Association, Kent, OH 44240.
ANA House of Delegates opposes mandatory HIV testing. Supports BSN requirement for taking generalist certification exams.
Md Nurse. 1991 Aug;10(5):1. Unique Identifier : AIDSLINE MED/92065659
McCaslin N
[The number of reports of HIV cases is still stable in Sweden--but it is impossible to estimate the number of HIV-infected persons in the next 40 years]
Lakartidningen. 1991 Nov 13;88(46):3909-12. Unique Identifier : AIDSLINE MED/92065679
Giesecke J; Forskarstipendiat i epidemiologi vid London School of Hygiene and; Tropical Medicine.
[CNS changes can be present in asymptomatic HIV infection]
Lakartidningen. 1991 Nov 20;88(47):4004-5. Unique Identifier : AIDSLINE MED/92065696
Alexius B; Psykiatriska mottagningen, Roslagstulls sjukhus, Stockholm.
[History and current status of laboratory research: the mysteries of HIV are being discovered step by step after an exceptional international research mobilization]
Lakartidningen. 1991 Nov 27;88(48):4132-4, 4137. Unique Identifier : AIDSLINE MED/92065715
Wahren B
[More drugs against HIV/AIDS will soon be available as a review over the drug development shows]
Lakartidningen. 1991 Nov 27;88(48):4139-42. Unique Identifier : AIDSLINE MED/92065716
Oberg B; Virologiska institutionen, Karolinska institutet, Stockholm.
Extrapulmonary tuberculosis in patients with human immunodeficiency virus infection.
Medicine (Baltimore). 1991 Nov;70(6):384-97. Unique Identifier : AIDSLINE MED/92065794
Shafer RW; Kim DS; Weiss JP; Quale JM; Department of Medicine, State University of New York-Health; Sciences Center, Brooklyn.
The annual number of cases of culture-proven extrapulmonary tuberculosis (TB) at our hospital increased from 47 cases in 1983 to 113 cases in 1988. At least 43% (199) of 464 consecutive patients with extrapulmonary TB during this 6-year period were infected with the human immunodeficiency virus (HIV); since HIV serolo


BCG vaccination and pediatric HIV infection--Rwanda, 1988-1990.
MMWR Morb Mortal Wkly Rep. 1991 Dec 6;40(48):833-6. Unique Identifier : AIDSLINE MED/92065921
In Africa, tuberculosis (TB) is one of the most common severe diseases associated with human immunodeficiency virus (HIV) infection. For infants in Rwanda and other countries where the risk for TB infection is high, the World Health Organization (WH


AIDS, monkeys and malaria [see comments]
Nature. 1991 Nov 28;354(6351):262. Unique Identifier : AIDSLINE MED/92065950
Gilks C; Nuffield Department of Clinical Medicine, John Radcliffe; Hospital, Oxford, UK.
Rural nurses join forces for AIDS care.
Nursingconnections. 1991 Fall;4(3):51-61. Unique Identifier : AIDSLINE MED/92066003
Fuszard B; Sowell RL; Hoff PS; Waters M
Rural hospitals and communities across the nation lack comprehensive services for AIDS patients. This study identified 15 vital services that are scarce in rural settings at a time when AIDS is showing a greater increase in rural than in urban areas. Analysis of responses from rural settings that have acquired service


[Hiv patients in a psychiatric outpatient clinic]
Ned Tijdschr Geneeskd. 1991 Nov 16;135(46):2180-3. Unique Identifier : AIDSLINE MED/92066025
Lunter CH; Sno HN; van den Boom FM; Nederlands Centrum Geestelijke Volksgezondheid, Utrecht.
The most often reported psychiatric complications among HIV-infected outpatients include: mood and anxiety disorders, and alcohol or nonopiate drug abuse. Medical records of 32 HIV-infected psychiatric outpatients in the Netherlands were studied. The most common DSM-III(-R) di


[Do we need a methadone maintenance program?]
Nervenarzt. 1991 Sep;62(9):524-8. Unique Identifier : AIDSLINE MED/92066056
Taschner KL; Psychiatrische Klinik des Burgerhospitals, Landeshauptstadt; Stuttgart.
Lung 99mTc DTPA transfer in renal disease and pulmonary infection.
Nephrol Dial Transplant. 1991;6(8):582-7. Unique Identifier : AIDSLINE MED/92066208
O'Doherty MJ; Breen D; Page C; Barton I; Nunan TO; Department of Nuclear Medicine, Rayne Institute, St Thomas'; Hospital, London, UK.
The half-time of transfer of 99mTc DTPA (T50) is a useful method of assessing lung epithelial permeability, which has been shown to be altered in patients with acquired immunodeficiency syndrome (AIDS) who have Pneumocystis carinii pneumonia (PCP). The present study was designed to assess the usefulness of the T50 mea


The meaning of living with AIDS: a study using Parse's theory of man-living-health.
Nurs Sci Q. 1991 Winter;4(4):175-9. Unique Identifier : AIDSLINE MED/92066276
Nokes KM; Carver K
This paper explores the meaning of living with Acquired Immune Deficiency Syndrome (AIDS) using Parse s theory of man-living-health as the conceptual framework. The design of the study is based on the qualitative descriptive method. Analysis of the data gathered from interviews with fourteen subjects reveals the emerg


AIDS newsletter [news]
N Z Dent J. 1991 Jul;87(389):101. Unique Identifier : AIDSLINE MED/92066277
A prospective study of infants of human immunodeficiency virus seropositive and seronegative women with a history of intravenous drug use or of intravenous drug-using sex partners, in the Bronx, New York City [published erratum appears in Pediatrics 1992 Feb;89(2):228]
Pediatrics. 1991 Dec;88(6):1248-56. Unique Identifier : AIDSLINE MED/92066425
Mayers MM; Davenny K; Schoenbaum EE; Feingold AR; Selwyn PA; Robertson V; Ou CY; Rogers MF; Naccarato M; Department of Pediatrics, North Central Bronx Hospital, New York.
A prospective study was conducted in the Bronx, New York, of 70 infants of human immunodeficiency virus (HIV)-infected (n = 33) and uninfected (n = 37) mothers who had a history of intravenous drug use or of intravenous drug-using sex partners. Infants were observed from birth to a median age of 23 months (range 3 to


Polymerase chain reaction (PCR) in various stages of HIV infection. Relationship to disease progression.
Nouv Rev Fr Hematol. 1991;33(3):245-9. Unique Identifier : AIDSLINE MED/92066444
Lefrere JJ; Mariotti M; Salpetrier J; Demange F; Wattel E; Rouger P; Vittecoq D; Institut National de Transfusion Sanguine, Paris, France.
In order to establish whether the Polymerase Chain Reaction (PCR) may constitute a new marker of evolution towards AIDS in symptomless HIV infected subjects, we used PCR with three primer pairs (in the gag, pol and LTR regions) in 223 seropositive individuals at different stages of HIV infection. Among 176 symptomless


Antibody to hepatitis C (anti C 100-3) in French hemophiliacs.
Nouv Rev Fr Hematol. 1991;33(3):263-6. Unique Identifier : AIDSLINE MED/92066447
Maisonneuve P; Laurian Y; Guerois C; Verroust F; Ferrer Le Coeur F; Courouce AM; Noel L; Centre d'Hematologie et de Transfusion Sanguine de Versailles,; Le Chesnay, France.
486 patients followed in four French hemophilia centres were tested for antibody to hepatitis C virus C100-3 recombinant protein. On samples collected in 1989, the overall incidence of anti-C 100-3 positivity was 66%. None of the 27 patients only exposed to solvent-detergent treated factor VIII or IX concentrates had


Identification of transcriptional suppressor proteins that bind to the negative regulatory element of the human immunodeficiency virus type 1.
Nucleic Acids Res. 1991 Nov 25;19(22):6107-12. Unique Identifier : AIDSLINE MED/92066454
Yamamoto K; Mori S; Okamoto T; Shimotohno K; Kyogoku Y; Institute for Protein Research, Osaka University, Japan.
Two different proteins which independently bound to neighboring sequences within the negative regulatory element (NRE) of human immunodeficiency virus type 1 (HIV-1) were detected in the nuclear extract of a virus-infected human T cell line. One of the factors bound to a novel dyad symmetrical sequence. This sequence


Detailed mutational analysis of TAR RNA: critical spacing between the bulge and loop recognition domains.
Nucleic Acids Res. 1991 Nov 25;19(22):6169-76. Unique Identifier : AIDSLINE MED/92066464
Berkhout B; Jeang KT; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, MD 20892.
Trans-activation of HIV-1 by the Tat protein is mediated through a cis-acting element (TAR) in the viral RNA. In order to obtain further insight into the molecular interactions for trans-activation, a detailed mutational analysis of TAR RNA was carried out. TAR RNA forms a hairpin structure with important sequence ele


AIDS family caregiving: transitions through uncertainty.
Nurs Res. 1991 Nov-Dec;40(6):338-45. Unique Identifier : AIDSLINE MED/92066518
Brown MA; Powell-Cope GM; School of Nursing, University of Washington, Seattle.
The purpose of this study was to describe the experience of AIDS family caregiving. Grounded theory provided the methodological basis for qualitative data generation and analysis. Extensive interviews were conducted with 53 individuals (lovers, spouses, parents of either adults or children with AIDS, siblings, and fri


The logistic regression model and the odds of testing HIV positive.
Nurs Res. 1991 Nov-Dec;40(6):372-3. Unique Identifier : AIDSLINE MED/92066525
Yarandi HN; Simpson SH; College of Nursing, University of Florida, Gainesville.
Knowledge, attitudes, beliefs, and behaviors of the business community relative to HIV-AIDS.
Public Health Rep. 1991 Nov-Dec;106(6):663-6. Unique Identifier : AIDSLINE MED/92066710
Farnham PG; NAIEP, Centers for Disease Control, Atlanta, GA 30333.
One of the goals of the Centers for Disease Control s (CDC) policy on the prevention of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) is to support business organizations in implementing HIV and AIDS information, education, and prevention activities. However, the response o


SPECT regional cerebral blood flow and neuropsychological testing in non-demented HIV-positive drug abusers: preliminary results.
Prog Neuropsychopharmacol Biol Psychiatry. 1991;15(5):649-62. Unique Identifier : AIDSLINE MED/92066739
Woods SW; O'Malley SS; Martini BL; McDougle CJ; Price LH; Krystal JH; Hoffer PB; Kosten TR; Yale University School of Medicine, New Haven, CT.
1. Non-demented HIV seropositive and seronegative methadone maintained patients and healthy volunteers (n = 10 each) participated. 2. All subjects underwent SPECT regional cerebral blood flow scanning following injection of Tc-99m HMPAO. All patients underwent neuropsychologic (NP) testing. 3. The left striatum/whole


Does peripheral blood T-lymphocyte population distribution in sarcoidosis provide a prognostic clue?
Sarcoidosis. 1991 Sep;8(2):129-33. Unique Identifier : AIDSLINE MED/92066832
Desrues B; Delaval P; Genetet N; Pencole C; Merdrignac G; Dassonville J; L'Huillier JP; Bourguet P; Kernec J; Service de Pneumologie, Hopital Pontchaillou, Rennes, France.
In its pulmonary form, sarcoidosis generally resolves spontaneously, but it may lead to fibrosis of the lung. The clinical, radiological and functional tests, as well as activity markers such as the serum angiotensin converting enzyme, intrathoracic uptake of 67Gallium and the cytological data provided by bronchoalveo


[A case from practice (229). HIV infection, group CDC IV B, C1, C2 with HIV encephalopathy]
Schweiz Rundsch Med Prax. 1991 Nov 12;80(46):1291-2. Unique Identifier : AIDSLINE MED/92066866
Laifer G; Medizinische Universitats-Poliklinik, Departement fur Innere; Medizin, Kantonsspital Basel.
[A case from practice (230). HIV infection CDC-class IV C1 with cryptosporidiosis]
Schweiz Rundsch Med Prax. 1991 Nov 19;80(47):1330-1. Unique Identifier : AIDSLINE MED/92066874
Eckhardt M; Medizinische Universitats-Poliklinik, Departement fur Innere; Medizin, Kantonsspital Basel.
A prospective study of 115 initially asymptomatic HIV infected gay men in Stockholm, Sweden.
Scand J Infect Dis. 1991;23(4):431-41. Unique Identifier : AIDSLINE MED/92066908
Karlsson A; Bratt G; Von Krogh G; Morfeldt-Manson L; Bottiger B; Sandstrom E; Department of Dermatovenereology Vanhalsan, Sodersjukhuset,; Stockholm, Sweden.
A cohort of 115 asymptomatic gay men, all seropositive for HIV, was recruited in a health screening project in Stockholm, Sweden , between Nov. 1982 and Dec. 1983 and subsequently followed and clinically evaluated after a mean observation time of 63 months. AIDS in accordance with t


Prevalence of antibodies to HTLV-1 in South American Indians (Mapuches) from Chile.
Scand J Infect Dis. 1991;23(4):507-8. Unique Identifier : AIDSLINE MED/92066919
Inostroza J; Diaz P; Saunier C; Immunology Laboratory, Temuco Hospital, Faculty of Medicine,; University de la Frontera, Chile.
The seroprevalence of HTLV-1 antibodies was investigated in 405 serum samples from healthy South American Indians (Mapuches) from Chile , using enzyme linked immunoassay (ELISA), Western immunoblot (WB) and radioimmuno precipitation assay (RIPA). Six samples were positive by ELISA; 3


Patients' views on the least acceptable increase in survival with zidovudine treatment.
Scand J Infect Dis. 1991;23(4):509-10. Unique Identifier : AIDSLINE MED/92066920
Gotzsche PC; Department of Infectious Diseases, Rigshospitalet, University of; Copenhagen, Denmark.
25 patients with AIDS or serious HIV infection were asked to specify the minimum time zidovudine should prolong life before they would be willing to take the drug for the rest of their lives. Most patients were unable to state a least acceptable survival benefit. Hence, the clinical relevance of sample size calculatio


Prevalence of mycobacterium avium complex infection in AIDS patients [letter; comment]
Scand J Infect Dis. 1991;23(4):511-2. Unique Identifier : AIDSLINE MED/92066921
Petrini B; Svahn A; Julander I; Kallenius G; Ostlund L
Tracking the AIDS drugs [news]
Science. 1991 Nov 22;254(5035):1113. Unique Identifier : AIDSLINE MED/92066950
[Diagnosis of Pneumocystis carinii pneumonia (PCP) in HIV-positive patients (letter)]
Ugeskr Laeger. 1991 Nov 4;153(45):3159-60. Unique Identifier : AIDSLINE MED/92067192
Lundgren JD; Nielsen JO
[Use of adsorption methods for plasma component apheresis]
Ugeskr Laeger. 1991 Nov 25;153(48):3388-92. Unique Identifier : AIDSLINE MED/92067232
Bang B; Heegaard NH; Proteinlaboratoriet, Kobenhavns Universitet.
Plasma-apheresis is a nonspecific and wasteful intervention requiring the use of potentially infectious and expensive replacement fluids. Selective removal of the unwanted plasma component circumvents most of the problems. For selective binding and removal of plasma components adsorption methods based on the principle


Regulation of gene expression in the human immunodeficiency virus type 1.
Adv Virus Res. 1991;40:1-17. Unique Identifier : AIDSLINE MED/92067589
Cullen BR; Howard Hughes Medical Institute, Duke University Medical Center,; Durham, North Carolina 27710.
Federal AIDS panel favors needle exchange [news]
Am Pharm. 1991 Oct;NS31(10):17-8. Unique Identifier : AIDSLINE MED/92067682
Zidovudine: counseling strategies and compliance.
Am Pharm. 1991 Oct;NS31(10):38-43. Unique Identifier : AIDSLINE MED/92067685
McKnight PT; Visconti JA; Gower RE; Para MF; AIDS Clinical Trial Unit, Ohio State University Hospitals.
AIDS, safety, and the drug approval process.
Am Pharm. 1991 Oct;NS31(10):44, 46. Unique Identifier : AIDSLINE MED/92067686
Uzych L
AIDS, death, and the drug approval process.
Am Pharm. 1991 Oct;NS31(10):45, 47. Unique Identifier : AIDSLINE MED/92067687
Berger JW
Who's making the decisions? [letter]
Am Pharm. 1991 Oct;NS31(10):8. Unique Identifier : AIDSLINE MED/92067693
Albert SG
Human T-cell lymphotropic virus type I infection and pregnancy: a case-control study and 12-month follow-up of 135 women and their infants.
Am J Obstet Gynecol. 1991 Nov;165(5 Pt 1):1438-43. Unique Identifier : AIDSLINE MED/92067781
Ville Y; Delaporte E; Peeters M; Leruez M; Glowaczower E; Fernandez H; Centre International de Recherche Medicale, Franceville, Gabon.
Human T-cell lymphotropic virus type I (HTLV-I) infection is common in Gabon , but its influence on pregnancy is unknown. A single case of acute T-cell leukemia in a pregnant woman has been reported in the literature, but, as far as we know, we present the first case-control study an


Caution with use of tricyclics in patients with AIDS [letter]
Am J Psychiatry. 1991 Dec;148(12):1750. Unique Identifier : AIDSLINE MED/92067852
Storch DD
Sense of smell and obsessional behavior [letter; comment]
Am J Psychiatry. 1991 Dec;148(12):1757. Unique Identifier : AIDSLINE MED/92067863
Goldberg ED; Goldberg RJ; Vannoppen B
Differential interference of alpha, beta or gamma interferons with HTLV-I integration and expression in vitro.
Ann Ist Super Sanita. 1991;27(1):127-32. Unique Identifier : AIDSLINE MED/92067971
D'Onofrio C; Alvino E; Peci E; Calio R; Bonmassar E; Dipartimento di Medicina Sperimentale e Scienze Biochimiche,; Universita degli Studi Tor Vergata, Rome, Italy.
Alpha, beta and gamma interferons (IFNs) can exert a powerful and direct antiviral activity against HTLV-I and can also modulate positively some cell-mediated immune functions of the host cell. These multiple effects of IFNs can induce a long-lasting inhibition of viral infection in recipient cells, probably by primin


[Acute neuropsychiatric manifestations in HIV infection: apropos of 5 clinical cases]
Ann Med Psychol (Paris). 1991 Apr;149(4):365-72. Unique Identifier : AIDSLINE MED/92068005
Kerneis H; Estrade JF; Samuel-Lajeunesse B; Clinique des Maladies mentales et de l'Encephale, Paris.
There is an increasing incidence of neuro psychological impairment in Acquired Immune Deficiency Syndrome patients. It is now recognized by certain authors as a 50 per cent (Nollet D. 88). This leads to increasing number of studies. As the AIDS epidemic continue psychiatrists have to become more familiar with this typ


Multiple releasable fluorescein labels for immunoassay: the principle illustrated by an immunoassay for antibodies to the human immunodeficiency virus.
Ann Clin Biochem. 1991 Sep;28 ( Pt 5):487-91. Unique Identifier : AIDSLINE MED/92068016
Bertram VM; Bailey MP; Rocks BF; Biochemistry Department, Royal Sussex County Hospital, Brighton,; UK.
Attempts to increase the sensitivity of fluorescein-based fluorescence immunoassays by using multiple labelling have generally been unsuccessful because of concentration quenching. We have labelled antibodies to human immunoglobulin G with multiple fluorescein fluorophores attached by means of a disulphide linkage: th


Comparative evaluation and practical importance of instrument-free HIV-1 antibody screening assays.
Ann Soc Belg Med Trop. 1991 Sep;71(3):237-42. Unique Identifier : AIDSLINE MED/92068079
Strecker K; Gurtler L; Binibangili M; Metzner-Hoffmann J; Strecker W; Hopital Presidentiel, Gbadolite, Zaire.
Four instrument-free, visually read assays for detection of HIV-1 antibody were evaluated using 1,133 serum specimens from blood donors and patients in a rural hospital in Northern Zaire . Sensitivity for the four assays ranged from 85.9% to 95.0% and specificity ranged from 88.5%


[Pulmonary hypertension secondary to talc microemboli in a HIV seropositive heroin-addict woman]
Arch Mal Coeur Vaiss. 1991 Sep;84(9):1369-73. Unique Identifier : AIDSLINE MED/92068095
Saadjian A; Gueunoun M; Philip-Joet F; Magnan A; Ebagosti A; Garbe L; Arnaud A; Levy S; Service de cardiologie, CHU Nord, Marseille.
Severe pulmonary hypertension presenting as acute cor pulmonare was observed in a HIV positive heroin addict. The usual aetiological investigations were negative. The apparently primary pulmonary hypertension was resistant oxygen and vasodilator therapy and was fatal in 6 months. Anatomopathological examination reveal


Persistent inapparent HIV-1 infection of human neuroblastoma cells.
Arch Virol. 1991;120(3-4):253-61. Unique Identifier : AIDSLINE MED/92068109
Vesanen M; Linna T; Vaheri A; Department of Virology, University of Helsinki, Finland.
We have studied human immunodeficiency virus type 1 (HIV-1) infection in three different human neuroblastoma cell lines; SK-N-MC, IMR-32 and SH-SY5Y. In all of these cell lines the infection became productive. However, the virus expression was different as determined by the p24 antigen capture assays from culture supe


There's no quick fix for AIDS.
Aust N Z J Psychiatry. 1991 Sep;25(3):314-21. Unique Identifier : AIDSLINE MED/92068147
Eisenberg L; Department of Social Medicine, Harvard Medical School, Boston, MA; 02115.
The epidemiology of AIDS reflects interactions among biological, psychological and social factors. The immune response to the infectious agent is relatively ineffectual; the course of the disease it produces is chronic. The long interval between HIV infection and the appearance of clinical disease maximizes silent tra


The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures.
Biochem Biophys Res Commun. 1991 Nov 27;181(1):402-8. Unique Identifier : AIDSLINE MED/92068225
Owens RA; Gesellchen PD; Houchins BJ; DiMarchi RD; Lilly Research Laboratories, Indianapolis, Indiana 46285.
Small peptides with activity as enzyme inhibitors, hormone antagonists, or other peptide mimetics, can be identified by synthesizing and screening large numbers of peptides as defined mixtures. Several coupling reactions, each with a different amino acid, can be conducted simultaneously and then combined to generate a


Nucleotide and amino acid homology between the human thyrotropin receptor and the HIV-1 Nef protein: identification and functional analysis.
Biochem Biophys Res Commun. 1991 Nov 27;181(1):498-505. Unique Identifier : AIDSLINE MED/92068240
Burch HB; Nagy EV; Lukes YG; Cai WY; Wartofsky L; Burman KD; Department of Medicine, Walter Reed Army Medical Center,; Washington, D.C. 20307-5001.
A comparison of the nucleotide sequence of the human thyrotropin receptor (hTSH-R) with that of HIV-1 revealed 61% homology between a 161 base pair region encoding a unique portion of the hTSH-R and an immunogenic HIV-1 regulatory protein, nef. Amino acid analysis of this region shows 27% homology, including a segment


[Neuropathologic study of 135 adult cases of acquired immunodeficiency syndrome (AIDS)]
Ann Pathol. 1991;11(4):236-47. Unique Identifier : AIDSLINE MED/92068278
Gray F; Geny C; Lionnet F; Dournon E; Fenelon G; Gherardi R; Poirier J; Departement de Neurosciences Medicales, Hopital Henri Mondor,; Creteil.
The central nervous system was examined in 135 adult AIDS patients who died between August 1982 and December 1990. Twenty two brains showed non-diagnostic changes including microglial nodules, discrete myelin pallor with reactive astrocytosis, mineralization of blood vessels and granular ependymitis. In 105 brains wit


Human T-cell lymphotropic virus type I associated adult T-cell leukaemia/lymphoma in Taiwan Chinese.
Br J Haematol. 1991 Oct;79(2):156-61. Unique Identifier : AIDSLINE MED/92068742
Shih LY; Kuo TT; Dunn P; Liaw SJ; Department of Internal Medicine, Chang Gung Memorial Hospital,; Chang Gung Medical College, Taipei, Taiwan, Republic of China.
Twenty-five Chinese patients with human T-cell lymphotropic virus type I (HTLV-I) associated adult T-cell leukaemia/lymphoma (ATLL) were identified in Taiwan . No patients had been outside Taiwan and none were descendants of Japanese


T cell sensitization to factor VIII in haemophilia A?
Br J Haematol. 1991 Oct;79(2):235-8. Unique Identifier : AIDSLINE MED/92068753
Madhok R; Smith J; Jenkins A; Lowe GD; University Department of Medicine, Royal Infirmary, Glasgow.
Previous studies have indicated that factor VIII concentrates have a direct inhibitory effect on the proliferation of peripheral blood mononuclear cells (PBMC) obtained from normal volunteers. We have studied the effects of an intermediate and high purity factor VIII concentrate on haemophiliac PBMC. Intermediate puri


Management of genital herpes simplex infection.
Int J STD AIDS. 1991 Sep-Oct;2(5):313-7. Unique Identifier : AIDSLINE MED/92069089
Thin RN
Herpes simplex infection of the genitals is a common condition, more often due to herpes simplex virus (HSV) type 2 than to type 1 virus. There is a severe first attack followed by mild recurrences which are more common and more frequent after HSV-2 than after HSV-1 genital infection. Clinical features with prodrome,


Hepatitis B: heterosexual transmission and vaccination strategies.
Int J STD AIDS. 1991 Sep-Oct;2(5):318-24. Unique Identifier : AIDSLINE MED/92069090
Boag F
'Through a glass darkly': reflections on genitourinary medicine.
Int J STD AIDS. 1991 Sep-Oct;2(5):325-32. Unique Identifier : AIDSLINE MED/92069091
Waugh MA; Department of Genito-Urinary Medicine, General Infirmary, Leeds,; UK.
Efficacy of chemical and/or surgical therapy against condylomata acuminata: a retrospective evaluation.
Int J STD AIDS. 1991 Sep-Oct;2(5):333-8. Unique Identifier : AIDSLINE MED/92069092
von Krogh G; Wikstrom A; Department of Dermatovenereology, Karolinska Hospital, Stockholm,; Sweden.
In order to estimate treatment resistance of condylomas, standardized records of 230 males aged 17-80 years (mean 27) attending at an STD clinic were analysed retrospectively. Anal warts occurred in 38 (17%) men; in 19 (50%) intranal warts were extensive enough to require further referral to the Department of Surgery.


Sentinel testing for the human immunodeficiency virus antibody at the Murray Street Clinic, Perth, Western Australia.
Int J STD AIDS. 1991 Sep-Oct;2(5):339-41. Unique Identifier : AIDSLINE MED/92069093
Kelly H; Sesnan K; Disease Control Branch, Health Department of Western Australia,; Murray Street Clinic, Perth.
Sentinel testing for human immunodeficiency virus (HIV) infection aims to monitor the HIV epidemic by testing subgroups of the population, and such testing has been carried out at the Murray Street Clinic in Perth, Western Australia since August 1989. This clinic is part of the


Factors associated with the detection of Entamoeba histolytica in homosexual men.
Int J STD AIDS. 1991 Sep-Oct;2(5):346-50. Unique Identifier : AIDSLINE MED/92069095
Law CL; Walker J; Qassim MH; STD Centre, Sydney Hospital, Australia.
In a study of bowel parasites in 128 Australian homosexual men attending a sexually transmitted diseases (STD) clinic, Entamoeba histolytica was detected in 37%, Giardia intestinalis in 3% and at least one protozoan in 81% of the group. There was no evidence of pathogenicity of E. histolytica, nor was there any associ


Distribution of HIV and acute hepatitis B infection among drug injectors in Glasgow.
Int J STD AIDS. 1991 Sep-Oct;2(5):356-8. Unique Identifier : AIDSLINE MED/92069097
Gruer LD; Peedle M; Carrington D; Clements GB; Follett EA; HIV and AIDS Resource Centre, Ruchill Hospital, Glasgow.
This study compared the distributions of known human immunodeficiency virus (HIV) and acute hepatitis B virus (HBV) infection among drug injectors in Glasgow over a 3.5 year period. Data were obtained from all relevant laboratory request forms submitted to Glasgow s 3 virology laboratories during the period 1 January


Evaluation of an enzyme immunoassay (Chlamydiazyme) with confirmatory test for the detection of chlamydial antigen in urine from men.
Int J STD AIDS. 1991 Sep-Oct;2(5):359-61. Unique Identifier : AIDSLINE MED/92069098
Mumtaz G; Ridgway GL; Clark S; Allason-Jones E; Department of Clinical Microbiology, University College Hospital,; London, UK.
First catch urine specimens from 312 male patients were examined for the presence of chlamydial antigen by an enzyme immunoassay (Chlamydiazyme). Positive results were repeated and confirmed using a blocking assay. In addition, urethral swabs were examined by cell culture for Chlamydia trachomatis. Discrepant results


Is bacterial vaginosis a sexually transmitted disease?
Int J STD AIDS. 1991 Sep-Oct;2(5):362-4. Unique Identifier : AIDSLINE MED/92069099
Larsson PG; Platz-Christensen JJ; Sundstrom E; Department of Obstetrics and Gynecology, Central Hospital,; Skovde, Sweden.
The sexual behaviour of 400 women with and 400 women without bacterial vaginosis from a health screening programme was investigated by a questionnaire to see if women with bacterial vaginosis had similar behaviours to women considered at risk for STDs. These patients were randomly selected from computer records. Eight


Value of examining the sexual partners of women suffering from initial genital herpes.
Int J STD AIDS. 1991 Sep-Oct;2(5):365-6. Unique Identifier : AIDSLINE MED/92069100
Woolley PD; Department of Genitourinary Medicine, Royal Hallamshire Hospital,; Sheffield, UK.
In a retrospective clinical audit of patient records to determine the value of examining the sexual partners of women with initial genital herpes , it was evident that only the regular partners attended for screening. Twenty-six per cent of women with initial genital herpes and 1


Use of the Cytobrush for concurrent cytology and chlamydia sampling: a comparison of immunofluorescence and culture for detection of chlamydia.
Int J STD AIDS. 1991 Sep-Oct;2(5):367-8. Unique Identifier : AIDSLINE MED/92069101
Szarewski A; Pompey A; Cronin D; Bertrand J; Bradbeer C; Thin RN; Department of Genitourinary Medicine, St Thomas' Hospital,; London, UK.
Five hundred and thirty-three women attending a genitourinary medicine clinic underwent concurrent cytology and Chlamydia trachomatis screening using a Cytobrush (Medscand AB). In each case, the same Cytobrush was used to give a sample for direct immunofluorescence and culture. 11.1% of samples were positive by immuno


Polyarthropathy in an HIV antibody positive patient.
Int J STD AIDS. 1991 Sep-Oct;2(5):371-2. Unique Identifier : AIDSLINE MED/92069103
Coker RJ; Harris JR; Department of Genito-Urinary Medicine, St Mary's Hospital,; London, UK.
AIDS literature index.
Int J STD AIDS. 1991 Sep-Oct;2(5):373-90. Unique Identifier : AIDSLINE MED/92069104
[A new case of Hodgkin's disease in an HIV carrier (letter)]
An Med Interna. 1991 Sep;8(9):470. Unique Identifier : AIDSLINE MED/92069196
Perez Penate MC; Mataix Corbi R; Hernandez Navarro F
Human immunodeficiency virus and the acquired immunodeficiency syndrome in obstetrics.
Curr Opin Obstet Gynecol. 1991 Oct;3(5):692-7. Unique Identifier : AIDSLINE MED/92069218
Sperling RS; Mount Sinai Medical Center, New York, New York.
Human immunodeficiency virus infections complicating pregnancy have become a major public health problem worldwide. Infected women may transmit the virus to offspring and longitudinal studies have reported this risk to be from 13% to 40%. Differences in reported transmission risks are likely to be related to maternal


Tuberculosis in HIV-infected patients presents problems [letter; comment]
Br J Hosp Med. 1991 Nov;46(5):293. Unique Identifier : AIDSLINE MED/92069469
Ash S
Mycobacterium avium-intracellulare infection in the acquired immunodeficiency syndrome.
Br J Hosp Med. 1991 Nov;46(5):295-300. Unique Identifier : AIDSLINE MED/92069474
Scoular A; French P; Miller R; Department of Genitourinary Medicine, Middlesex Hospital, London.
Disseminated infection with Mycobacterium avium and M. intracellulare (MAI) is increasingly recognized as a significant contributor to both increased illness and death in patients with acquired immunodeficiency syndrome. Early reports of treatment of MAI were disappointing but recent studies have shown that combinatio


TB and HIV [news]
Br J Hosp Med. 1991 Nov;46(5):344. Unique Identifier : AIDSLINE MED/92069487
Psychiatric illnesses in patients with HIV infection and AIDS referred to the liaison psychiatrist.
Br J Psychiatry. 1991 Sep;159:347-50. Unique Identifier : AIDSLINE MED/92069495
Seth R; Granville-Grossman K; Goldmeier D; Lynch S; Bethlem Royal and Maudsley Hospital, London.
All referrals made to the liaison psychiatric service for HIV and AIDS patients over one year were reviewed. ICD-9 and CDC diagnoses were applied to each case at presentation. Sixty HIV-positive patients were assessed, of whom 35 had affective disorder, which was significantly associated with CDC group IV disease (AID


The World Health Organization's cross-cultural study on neuropsychiatric aspects of infection with the human immunodeficiency virus 1 (HIV-1). Preparation and pilot phase.
Br J Psychiatry. 1991 Sep;159:351-6. Unique Identifier : AIDSLINE MED/92069496
Maj M; Janssen R; Satz P; Zaudig M; Starace F; Boor D; Sughondhabirom B; Bing EG; Luabeya MK; Ndetei D; et al; World Health Organization, Division of Mental Health/Global; Programme on AIDS, Geneva, Switzerland.
The WHO launched a multicentre study to explore the nature and prevalence of HIV-1-associated neurological, psychiatric, and neuropsychological abnormalities in persons living in different geographical and sociocultural contexts. The study is being conducted in Brazil ,


Behavioural treatment of AIDS-focused illness phobia.
Br J Psychiatry. 1991 Sep;159:422-5. Unique Identifier : AIDSLINE MED/92069508
Logsdail S; Lovell K; Warwick H; Marks I; Maudsley Hospital, Denmark Hill, London.
Seven cases are described in which the central symptoms were fear of contracting AIDS, avoidance of related cues, rituals and reassurance-seeking. Associated features include previous illness phobias and obsessive-compulsive disorder. Treatment with exposure and response prevention (plus a cognitive session in one cas


Guidelines on ethical and legal considerations in anonymous unlinked HIV seroprevalence research [letter; comment]
Can Med Assoc J. 1991 Dec 1;145(11):1418-9. Unique Identifier : AIDSLINE MED/92069698
Emson HE
Transmission of HIV, hepatitis B virus, and other bloodborne pathogens in health care settings: a review of risk factors and guidelines for prevention. World Health Organization.
Bull World Health Organ. 1991;69(5):623-30. Unique Identifier : AIDSLINE MED/92069801
Hu DJ; Kane MA; Heymann DL; Global Programme on AIDS, World Health Organization, Geneva,; Switzerland.
Recent reports of the transmission of human immunodeficiency virus (HIV) in health care settings have caused considerable public health concern. HIV as well as hepatitis B virus (HBV) and other bloodborne pathogens do constitute infectious hazards in certain settings. Transmission has been reported from patient to pat


The current status of cat-scratch disease: an update.
Comp Immunol Microbiol Infect Dis. 1991;14(3):223-8. Unique Identifier : AIDSLINE MED/92070069
Arlet G; Perol-Vauchez Y; Service de Bacteriologie-Virologie, Hopital Saint-Louis, Paris,; France.
Cat-scratch disease (CSD) is a benign inoculative lymphoreticulosis, first described in independent reports by Pierre Mollaret [1] and Robert Debre in 1950 [2]. The disease usually self-limited, with spontaneous resolution occurring after several weeks, appears to be related to the presence of an identified gram-negat


Prognostic significance of the evaluation of bronchoalveolar lavage cell populations in patients with HIV-1 infection and pulmonary involvement.
Chest. 1991 Dec;100(6):1601-6. Unique Identifier : AIDSLINE MED/92070181
Agostini C; Zambello R; Trentin L; Poletti V; Spiga L; Gritti F; Cipriani A; Salmaso L; Cadrobbi P; Semenzato G; Padua University School of Medicine, Department of Clinical; Medicine, Italy.
To investigate the prognostic utility of the morphologic and immunologic evaluation of BAL cell populations in determining mortality risk, we analyzed BAL data obtained from 115 patients infected with HIV-1. Forty fatal outcomes occurred within 73 patients with OI. The OI patients who died showed a significant increas


Aspergillosis in the acquired immunodeficiency syndrome.
Chest. 1991 Dec;100(6):1614-8. Unique Identifier : AIDSLINE MED/92070183
Klapholz A; Salomon N; Perlman DC; Talavera W; Department of Medicine, Beth Israel Medical Center, New York.
The role of Aspergillus species as a pathogen in acquired immunodeficiency syndrome (AIDS) has not been clearly defined. From 1984 to 1989, more than 2,000 AIDS patients were seen at Beth Israel Medical Center, New York. Aspergillus was isolated in ten patients; seven had invasive disease and three had noninvasive dis


Diagnosis of mediastinal mycobacterial lymphadenopathy by transbronchial needle aspiration [see comments]
Chest. 1991 Dec;100(6):1723-4. Unique Identifier : AIDSLINE MED/92070201
Baron KM; Aranda CP; New York University Department of Pulmonary and Critical Care; Medicine, New York.
A 35-year-old man with the acquired immunodeficiency syndrome (AIDS) presented with a multitude of constitutional symptoms, fever, and marked intrathoracic lymphadenopathy. Results of initial diagnostic examination were unrevealing, and bronchoscopy with fine-gauge flexible transbronchial needle aspiration (TBNA) of s


Lymphocytic interstitial pneumonitis presenting as recurrent pneumothoraces.
Chest. 1991 Dec;100(6):1733-5. Unique Identifier : AIDSLINE MED/92070206
Parker JS; Shellito J; Pei LA; Mason CM; Louisiana State University Medical Center, Department of; Medicine, New Orleans 70112-2822.
A 34-year-old woman seronegative for the human immunodeficiency virus presented with recurrent, bilateral pneumothoraces. She also had bibasilar interstitial and alveolar infiltrates, and histologic examination was consistent with lymphocytic interstitial pneumonitis. To our knowledge, this is the first documented cas


Interaction of seminal plasma proteins with cell surface antigens: presence of a CD4-binding glycoprotein in human seminal plasma.
Exp Cell Res. 1991 Dec;197(2):268-71. Unique Identifier : AIDSLINE MED/92070399
Autiero M; Abrescia P; Guardiola J; International Institute of Genetics and Biophysics, University of; Naples, Italy.
We report in this paper the presence in the human seminal plasma of a glycoprotein capable of binding to CD4, a surface antigen expressed on the surface of T-cells, macrophages, and sperm cells, which acts as a coreceptor in antigen-mediated T-cell activation and as a receptor for the AIDS virus, HIV-1. This protein,


Mutational analysis of the HTLV-I trans-activator, Tax.
FEBS Lett. 1991 Nov 4;292(1-2):210-2. Unique Identifier : AIDSLINE MED/92070492
Heder A; Paca-Uccaralertkun S; Boros I; Institute of Biochemistry, Biological Research Center, Szeged,; Hungary.
The gene coding for the trans-activating factor (Tax) of the human T-cell leukemia virus, type I (HTLV-I) was mutagenized in vitro using oligonucleotide-directed mutagenesis and recombinant DNA techniques. All except one of the mutagenized tax constructs failed to trans-activate the HTLV-I LTR in a eukaryotic test sys


Structural characterization of a 39-residue synthetic peptide containing the two zinc binding domains from the HIV-1 p7 nucleocapsid protein by CD and NMR spectroscopy.
FEBS Lett. 1991 Nov 4;292(1-2):25-30. Unique Identifier : AIDSLINE MED/92070501
Omichinski JG; Clore GM; Sakaguchi K; Appella E; Gronenborn AM; Laboratory of Chemical Physics, National Institute of Diabetes; and Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, MD 20892.
A 39-residue peptide (p7-DF) containing the two zinc binding domains of the p7 nucleocapsid protein was prepared by solid-phase peptide synthesis. The solution structure of the peptide was characterized using circular dichroic and nuclear magnetic resonance spectroscopy in both the presence and absence of zinc ions. C


Fibronectin is a non-viral substrate for the HIV proteinase.
FEBS Lett. 1991 Nov 4;292(1-2):298-300. Unique Identifier : AIDSLINE MED/92070512
Oswald M; von der Helm K; Pettenkofer Institute, University of Munich, Germany.
The retrovirus encoded proteinase (PR) is required for the proper maturation of viral particles into infectious virus. The PR had been considered highly substrate specific, cleaving exclusively the viral gag and gag-pol protein precursor. It has recently been reported, however, that cytoskeleton and other cellular fil


Purification and characterization of human T-cell leukemia virus type I protease produced in Escherichia coli.
FEBS Lett. 1991 Nov 18;293(1-2):106-10. Unique Identifier : AIDSLINE MED/92070535
Kobayashi M; Ohi Y; Asano T; Hayakawa T; Kato K; Kakinuma A; Hatanaka M; Biotechnology Research Laboratories, Takeda Chemical Industries,; Ltd., Osaka, Japan.
Human T-cell leukemia virus type I (HTLV-I) protease has been purified to homogeneity from a strain of recombinant Escherichia coli. The protease was expressed as a larger precursor, which was autoprocessed to form a mature protease. Protein chemical analyses revealed the coding sequence of mature protease, which agre


[Are the HIV viruses really the causal agents of AIDS?]
Gac Med Mex. 1991 Jan-Feb;127(1):75-84. Unique Identifier : AIDSLINE MED/92070678
Benitez Bribiesca L; Unidad de Investigacion Clinica en Enfermedades Oncologicas,; Instituto Mexicano del Seguro Social.
Since the discovery and characterization of the Human Immunodeficiency Viruses (HIV) it seems to be firmly established that these infectious agents are the cause of AIDS. Since a few years ago, however, we and other investigators have noted a number of unexplained facts that cast many doubts over the simplistic hypoth


[The importance of tuberculosis in the acquired immunodeficiency syndrome. The clinical and therapeutic aspects]
Gac Med Mex. 1991 Mar-Apr;127(2):137-41. Unique Identifier : AIDSLINE MED/92070684
Cano-Dominguez C; Villarreal-Urenda C; Gomez-Campos G; Ramirez-Cruz F; Becerra-Carmona G; Centro Medico La Raza, Instituto Mexicano del Seguro Social.
These is presented a study of 50 patients suffering TB and AIDS. The universe was divided in two: group I, when TB was considered the first manifestation of AIDS; (27 males and 2 females). Group II, when TB was preceded by some opportunistic infection, some kind of cancer, or some clinical symptoms compatible with was


Autoantibodies in male homosexuals and HIV infection.
Immunol Lett. 1991 Sep;30(1):31-5. Unique Identifier : AIDSLINE MED/92070984
Argov S; Schattner A; Burstein R; Handzel ZT; Shoenfeld Y; Bentwich Z; Unit for Autoimmune Diseases, Ben-Gurion University, Beer-Sheba,; Israel.
We have used ELISA to study the frequency of autoantibodies to several antigens in the serum of 17 male homosexuals (MHS) negative for HIV (HIV-), 11 asymptomatic HIV seropositive MHS (HIV+) and patients with ARC (N = 15) or AIDS (N = 13), and compared them to 20 matched healthy heterosexual controls. Serum antibody b


Sexual behavior, attitudes toward safer sex, and gender among a cohort of 244 recovering i.v. drug users.
Int J Addict. 1991 Aug;26(8):859-77. Unique Identifier : AIDSLINE MED/92071076
Schilling RF; el-Bassel N; Schinke SP; Nichols S; Botvin GJ; Orlandi MA; Columbia University School of Social Work, New York, New York; 10025.
Heterosexual contact with drug users is a major route of AIDS transmission. This study of 135 male and 109 female methadone maintenance patients described subjects sexual behavior, preventive practices and attitudes toward safer sex; explored ethnic-racial differences in high risk sexual behavior and attitudes; and e


[Foudroyant course of generalized cryptococcosis without signs of immune deficiency]
Internist (Berl). 1991 Sep;32(9):553-5. Unique Identifier : AIDSLINE MED/92071110
Krupp A; Ravens KG; Medizinische Klinik I der Henriettenstiftung, Hannover.
Headache in HIV-1-related disorders.
Headache. 1991 Sep;31(8):518-22. Unique Identifier : AIDSLINE MED/92071146
Lipton RB; Feraru ER; Weiss G; Chhabria M; Harris C; Aronow H; Newman LC; Solomon S; Department of Neurology, Albert Einstein College of Medicine,; Bronx, NY.
To define the causes, clinical significance and characteristics of headaches in HIV-1-related disorders, we studied 49 consecutive HIV-1 infected patients who presented with headache. Work-up included CT scans, cerebrospinal fluid examinations (in the absence of a contraindication) and serologic studies. Overall, 40 o


Prevalence of HIV-1 antibodies in patients attending tuberculosis clinics in Pune [letter] [see comments]
J Assoc Physicians India. 1991 May;39(5):427. Unique Identifier : AIDSLINE MED/92071300
Ranadive SN; Thakar MR; Kulkarni SS; Sukumaran K; Gokhale NT; Rodrigues JJ; Banerjee K
Disseminated pneumocystis carinii infection in AIDS.
J Clin Pathol. 1991 Oct;44(10):820-3. Unique Identifier : AIDSLINE MED/92071347
Coker RJ; Clark D; Claydon EL; Gompels M; Ainsworth JG; Lucas SB; Miller R; Goldin RD; Pinching AJ; Harris JR; Department of Genitourinary Medicine, St. Mary's Hospital and; Medical School, London.
Eight patients with AIDS and Pneumocystis carinii infection were studied. Protean manifestations were a feature not untypical of disseminated pneumocystosis. Aerosolised pentamidine as prophylaxis against P carinii pneumonia was ineffective at suppressing dissemination. The knowledge that extrapulmonary infection can


No evidence of HTLV-I infection in French patients with multiple sclerosis using the polymerase chain reaction.
J Clin Pathol. 1991 Oct;44(10):871-2. Unique Identifier : AIDSLINE MED/92071361
Wattel E; Mariotti M; Bignon JD; Agis F; Gordien E; Muller JY; Hors J; Lefrere JJ; Institut National de Transfusion Sanguine, Paris, France.
The polymerase chain reaction (PCR), using three primer pairs in the pol, tax, and env regions of the HTLV-I genome, was unable to detect HTLV-I in the blood samples of 54 caucasian subjects with multiple sclerosis who were seronegative for HTLV-I/II. Seventeen HTLV-I/II seropositive (by ELISA and Western blot) subjec


Treatment of hepatitis B virus infection with interferon. Factors predicting response to interferon.
J Hepatol. 1991;13 Suppl 1:S4-7. Unique Identifier : AIDSLINE MED/92071544
Thomas HC; Karayiannis P; Brook G; Academic Department of Medicine, St. Mary's Hospital Medical; School, London, United Kingdom.
Several randomised controlled trials have been undertaken to evaluate the efficacy of alpha-interferon in the therapy of chronic hepatitis B. In patients with HBe antigen-positive disease acquired in adult life the response rates vary from 25-50%. In those infected at birth, response rates are lower. Twenty-one pretre


Treatment with interferon of chronic hepatitis B associated with antibody to hepatitis B e antigen.
J Hepatol. 1991;13 Suppl 1:S8-11. Unique Identifier : AIDSLINE MED/92071545
Brunetto MR; Oliveri F; Demartini A; Calvo P; Manzini P; Cerenzia MT; Bonino F; Division of Gastroenterology, Molinette Hospital, Torino, Italy.
Persistence of HBV replication (serum HBV-DNA and intrahepatic HBcAg) and markers of HBV-induced (IgM anti-HBc positive) liver disease in anti-HBe-positive patients characterize a peculiar form of chronic hepatitis B. This form of hepatitis B prevails in the Mediterranean Basin, Middle and Far East and is associated w


Evaluation of a new human immunodeficiency virus (HIV) antibody detection method based on time-resolved fluoroimmunoassay.
J Immunol Methods. 1991 Nov 5;144(1):57-61. Unique Identifier : AIDSLINE MED/92071576
Ushijima H; Nakate H; Kohno H; Okuda K; Division of AIDS Virus, National Institute of Health, Tokyo,; Japan.
We have developed a time-resolved fluoroimmunoassay for the detection of anti-HIV antibody using purified virus, recombinant gp120 or a synthetic peptide derived from gp41. The results of time-resolved fluoroimmunoassay correlated well with those obtained by enzyme immunoassay and with the results of immunoblotting. T


A fluorometric assay to monitor mitogenic stimulation of human lymphocytes.
J Immunol Methods. 1991 Nov 22;144(2):223-9. Unique Identifier : AIDSLINE MED/92071590
Bialek R; Abken H; Zentrum fur Kinderheilkunde, Universitat Bonn, F.R.G.
A fluorometric assay using Hoechst 33342 to measure DNA in cell culture has been applied to detect mitogenic stimulation of human lymphocytes. Mononuclear cells from the peripheral blood of healthy donors and of HIV infected patients were stimulated with mitogens (PHA and ConA, respectively) in serum-free culture medi


HIV and Mr. Helms [editorial] [see comments]
J Fla Med Assoc. 1991 Aug;78(8):481-2. Unique Identifier : AIDSLINE MED/92071699
Caldwell JR
Acquired immune deficiency syndrome-related Kaposi's sarcoma [letter; comment]
J Clin Oncol. 1991 Dec;9(12):2235-7. Unique Identifier : AIDSLINE MED/92071762
Krown SE
Attitudes toward AIDS among a low-risk group of women.
J Obstet Gynecol Neonatal Nurs. 1991 Sep-Oct;20(5):398-405. Unique Identifier : AIDSLINE MED/92071780
Glenn PS; Nance-Spronson LE; McCartney M; Yesalis CE; St. Paul Ramsey Medical Center, Minnesota.
A descriptive study presents the results of a 31-item questionnaire surveying the attitudes, fears, and perceived risks regarding acquired immunodeficiency syndrome (AIDS) of patients at a freestanding maternity center located in a Washington, DC, suburb. The nonprobability, convenience sample of 200 females consists


Pneumocystis carinii pneumonia despite prophylaxis in children with human immunodeficiency virus infection [see comments]
J Pediatr. 1991 Dec;119(6):992-4. Unique Identifier : AIDSLINE MED/92071835
Mueller BU; Butler KM; Husson RN; Pizzo PA; Pediatric Branch, National Cancer Institute, National Institutes; of Health, Bethesda, Maryland 20892.
Cell receptors as drugs. Ligand binding domains of receptors as drugs: a potential new class of therapeutic agents.
J R Coll Physicians Lond. 1991 Oct;25(4):309-11. Unique Identifier : AIDSLINE MED/92071914
Yarbrough GG; Taylor DP; Fermentation Service, Panlabs Incorporated, Bothell, Washington.
Modern technology applied to the study of receptor proteins has revealed that distinct structural domains of these molecules subserve different functions. With many receptors it is known that a soluble, extracellular portion of the molecule is responsible for the recognition and binding of endogenous or exogenous liga


Neurosyphilis yesterday and today [see comments]
J R Coll Physicians Lond. 1991 Oct;25(4):321-4. Unique Identifier : AIDSLINE MED/92071916
Nieman EA; St Mary's Hospital, London.
Ten years ago it might have been predicted that neurosyphilis would disappear, but this has not happened. It has altered in character so that almost all of the cases seen are meningovascular in type. Even with the acceleration of neurosyphilis that occurs with immunodeficiency it is unlikely that there will be a resur


AIDS--therapeutic strategies and models of care. The Watson Smith Lecture 1991.
J R Coll Physicians Lond. 1991 Oct;25(4):332-8. Unique Identifier : AIDSLINE MED/92071920
Pinching AJ; St Mary's Hospital Medical School, London.
Combined naloxone/methadone preparations for opiate substitution therapy.
J Subst Abuse Treat. 1991;8(3):157-60. Unique Identifier : AIDSLINE MED/92072012
Loimer N; Presslich O; Grunberger J; Linzmayer L; Department of Psychiatry, University of Vienna, Austria.
Every opportunity should be used to reduce the risk of HIV-1 infection and transmission among intravenous drug users (IVDUs). Methadone maintenance is widely accepted to keep the drug user away from risk-laden practices and to stop intravenous drug use. In order to minimize the diversion and intravenous abuse of metha


Informed consent for transfusions [letter]
J Thorac Cardiovasc Surg. 1991 Dec;102(6):934-5. Unique Identifier : AIDSLINE MED/92072318
Holland PV
Application of nested polymerase chain reaction for the detection of HTLV-I genome.
Leukemia. 1991 Nov;5(11):1010-1. Unique Identifier : AIDSLINE MED/92072355
Shiokawa S; Yasuda M; Yamamoto M; Nobunaga M; Department of Clinical Immunology, Medical Institute of; Bioregulation, Kyushu University, Oita, Japan.
[Acquired immunodeficiency syndrome in the province of Cadiz. A study of 269 consecutive patients]
Med Clin (Barc). 1991 Oct 5;97(11):404-9. Unique Identifier : AIDSLINE MED/92072371
Vergara de Campos A; Perez Moreno JM; Bascunana Quirell A; Torres Tortosa M; Perez Jimenez FJ; Perez Cortes S; Castillo Palma MJ; Perez Perez M; Lorente Campos J; Hospital Universitario de Puerto Real.
BACKGROUND: The epidemiological characteristics, clinical manifestations and survival were analyzed in 269 patients with acquired immunodeficiency syndrome (AIDS) diagnosed in the province of Cadiz up to June 1970. METHODS: A multicenter protocol study including the 7 hospitals attending practically all of the populat


Practice protocol for physicians with HIV [news]
Md Med J. 1991 Nov;40(11):979-80. Unique Identifier : AIDSLINE MED/92072431
Putting state's AIDS hysteria into global perspective.
Minn Med. 1991 Oct;74(10):15-6. Unique Identifier : AIDSLINE MED/92072520
Shultz JM; University of Miami School of Medicine.
Physicians with AIDS. Healing the crisis of confidence.
Minn Med. 1991 Oct;74(10):18-23. Unique Identifier : AIDSLINE MED/92072521
Feldman MK
Documented male-to-female transmission of HIV-1 after minimal vaginal exposure in the absence of other cofactors for infection.
Minn Med. 1991 Oct;74(10):32-4. Unique Identifier : AIDSLINE MED/92072523
Henry K; HIV/AIDS Clinic and Programs, St. Paul-Ramsey Medical Center.
AIDS cases attributable to heterosexual vaginal intercourse constitute a growing proportion of new AIDS cases in the United States . Major cofactors that possibly increase the efficiency of heterosexual transmission of HIV-1 include genital ulcer disease, multiple sexual exposures, lack


HIV and AIDS resources.
Minn Med. 1991 Oct;74(10):34. Unique Identifier : AIDSLINE MED/92072524
Henry K; Melroe NH; HIV/AIDS Clinic and Programs, St. Paul-Ramsey Medical Center.
HIV in the health care setting. Walk carefully in this confusing legal landscape.
Minn Med. 1991 Oct;74(10):37-42. Unique Identifier : AIDSLINE MED/92072525
Prentnieks ME; Minnesota Medical Association, Minneapolis 55414.
Fighting AIDS with reason and cooperation [editorial]
Minn Med. 1991 Oct;74(10):5. Unique Identifier : AIDSLINE MED/92072526
Burke EC
Drug use and sexual behaviors among sex partners of injecting-drug users--United States, 1988-1990.
MMWR Morb Mortal Wkly Rep. 1991 Dec 13;40(49):855-60. Unique Identifier : AIDSLINE MED/92072533
The National AIDS Demonstration Research (NADR) Program of the National Institute on Drug Abuse evaluates community-based outreach and prevention efforts targeted to injecting-drug users (IDUs) and their sex partners. These sex partners who are not IDUs are at substantial risk for human immunodeficiency virus (HIV) in


Tuberculosis and HIV infection [letter; comment]
N Engl J Med. 1991 Dec 26;325(26):1882-4. Unique Identifier : AIDSLINE MED/92072642
Paediatric AIDS.
Nurs RSA. 1991 Aug;6(8):16. Unique Identifier : AIDSLINE MED/92072675
Allan B
FDA approves Epoetin Alfa use for AZT patients [news]
Nephrol News Issues. 1991 Apr;5(4):11. Unique Identifier : AIDSLINE MED/92072737
Deaths of two kidney transplant patients linked to AIDS-infected dono