Morphologic and immunoelectronmicroscopic identification of human T-cell lymphotropic virus type III (HTLV-III). NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Morphologic and immunoelectronmicroscopic identification of human T-cell lymphotropic virus type III (HTLV-III).

Histol Histopathol. 1986 Jan;1(1):43-7. Unique Identifier : AIDSLINE MED/92182351
Timar J; Nagy K; Lapis K; 1st Inst. of Pathol. and Exptl. Canc. Res., Semmelweis Med.; Univ., Budapest, Hungary.

Abstract: The AIDS associated HTLV-III virus infected H9 cells were extensively studied using light, scanning and transmission electronmicroscopy. It was demonstrated that the morphological features of HTLV-III are different from the C-type particles and are similar to those of lentiviridae. For immunological identification high titer pre-AIDS patient sera served as the anti-HTLV-III envelope antibody source. The immunoelectronmicroscopic method was able to identify the viral envelope antigen on the surface of infected cells and in certain areas of the viral envelope. This is the first application of immunoelectronmicroscopy for the identification of the HTLV-III virus.
Keywords: Cell Line/MICROBIOLOGY Comparative Study Diagnosis, Differential Human HIV Antigens/*ANALYSIS HIV Infections/*DIAGNOSIS HTLV-BLV Viruses/IMMUNOLOGY/*ULTRASTRUCTURE HTLV-I Infections/*DIAGNOSIS Immunohistochemistry/METHODS Microscopy, Immunoelectron JOURNAL ARTICLEKWDcellline/microbiologycomparativestudydiagnosis,differentialhumanhivantigens/KWDanalysishivinfections/KWDdiagnosishtlv-blvviruses/immunology/KWDultrastructurehtlv-iinfections/KWDdiagnosisimmunohistochemistry/methodsmicroscopy,immunoelectronjournalarticle
920630
M9261002

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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