Surgical management of endocarditis in drug addicts and long-term results. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Surgical management of endocarditis in drug addicts and long-term results.

J Card Surg. 1990 Mar;5(1):63-7. Unique Identifier : AIDSLINE MED/92173631
Frater RW; Albert Einstein School of Medicine Hospital, Bronx, NY 10461.

Abstract: From 1977 to May 1989, 57 successive patients who were known drug addicts with endocarditis were operated on at the Weiler Division of Montefiore Medical Center and the Albert Einstein College of Medicine. The most common lesion was aortic endocarditis. Thirty day in hospital mortality was 9%. Recurrent infection did not occur in the preAIDS era. Since the advent of HIV positive patients, failure of antibiotics to control the infection preoperatively has been seen and carries with it a severe risk of recurrent and fatal postoperative sepsis. The long-term survival was, at about 10% over 5-10 years, just good enough to warrant continued efforts in this very difficult group of patients.
Keywords: Antibiotics/THERAPEUTIC USE Endocarditis, Bacterial/DRUG THERAPY/PATHOLOGY/*SURGERY Heart Valve Prosthesis Human HIV Infections HIV Seropositivity Prognosis Prosthesis-Related Infections/SURGERY Substance Abuse, Intravenous *Substance Dependence JOURNAL ARTICLEKWDantibiotics/therapeuticuseendocarditis,bacterial/drugtherapy/pathology/KWDsurgeryheartvalveprosthesishumanhivinfectionshivseropositivityprognosisprosthesis-relatedinfections/surgerysubstanceabuse,intravenousKWDsubstancedependencejournalarticle
920630
M9260997

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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