HIV seroconversion and disinfection of injection equipment among intravenous drug users, Baltimore, Maryland. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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HIV seroconversion and disinfection of injection equipment among intravenous drug users, Baltimore, Maryland.

Epidemiology. 1991 Nov;2(6):444-6. Unique Identifier : AIDSLINE MED/92162814
Vlahov D; Munoz A; Celentano DD; Cohn S; Anthony JC; Chilcoat H; Nelson KE; Department of Epidemiology, Johns Hopkins School of Hygiene and; Public Health, Baltimore, MD.

Abstract: To examine the putative protective effect of disinfectant use on HIV seroconversion among intravenous drug users, we conducted a nested case-control study comparing 22 black heterosexual HIV seroconverters with 95 persistent seronegatives matched on gender, use of cocaine, date of study entry, and duration of follow-up. For intravenous drug users who reported using disinfectant all the time, the odds of seroconversion was 0.77 (95% CI: 0.25-2.38) compared with those who reported no use of disinfectants; for those who used disinfectants some of the time, the corresponding odds ratio was 0.91 (95% CI: 0.26-3.31). The odds ratio for use of disinfectant all the time was 0.63 (95% CI: 0.10-3.91) for those injecting at galleries and 1.08 (95% CI: 0.35-3.11) for those not injecting at galleries. These data suggest a limited protective effect of disinfectant use in the field which may be more beneficial to those injecting in shooting galleries.
Keywords: Adult Baltimore Case-Control Studies *Disinfection Human HIV Seropositivity/*EPIDEMIOLOGY Logistic Models Needle Sharing *Needles Odds Ratio Risk Factors *Substance Abuse, Intravenous Support, U.S. Gov't, P.H.S. JOURNAL ARTICLEKWDadultbaltimorecase-controlstudiesKWDdisinfectionhumanhivseropositivity/KWDepidemiologylogisticmodelsneedlesharingKWDneedlesoddsratioriskfactorsKWDsubstanceabuse,intravenoussupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
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Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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