[Infectivity by HIV of different blood products used in Aragon] NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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[Infectivity by HIV of different blood products used in Aragon]

An Med Interna. 1991 Nov;8(11):548-50. Unique Identifier : AIDSLINE MED/92162942
Lucia Cuesta JF; Garcia Aranda A; Servicio de Hematologia, Hospital Miguel Servet, Zaragoza.


Abstract: In our region, prevalence of anti-HIV antibodies among hemophiliacs B (83.3%) is higher than among hemophiliacs A (47%), as reported in other spanish communities and contrary to other countries, were the opposite phenomenon has been observed. This seems to be due to the volume of hemo-derivatives received, rather than to their different infectivity, as it has been suggested sometimes. In order to assess this infectivity, independently of doses, we have studied two groups of patients, hemophiliacs A transfused with factor III and non-hemophiliacs who had received concentrate of prothrombinic complex factors (CPCF), in doses lower than 10,000 units. Both groups were transfused during the period when seroconversions were observed in our area (1981-1985) and we demonstrated that the difference between their prevalences of anti-HIV antibodies was not statistically significant.
Keywords: Blood Coagulation Disorders/THERAPY Blood Coagulation Factors/*ADVERSE EFFECTS *Drug Contamination English Abstract Factor VIII/*ADVERSE EFFECTS Human *HIV Seroprevalence JOURNAL ARTICLEKWDbloodcoagulationdisorders/therapybloodcoagulationfactors/KWDadverseeffectsKWDdrugcontaminationenglishabstractfactorviii/KWDadverseeffectshumanKWDhivseroprevalencejournalarticle
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M9260976

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