Human herpesvirus 6 (HHV-6) infection and exanthem subitum in Thailand. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Human herpesvirus 6 (HHV-6) infection and exanthem subitum in Thailand.

Acta Paediatr Jpn. 1991 Aug;33(4):434-9. Unique Identifier : AIDSLINE MED/92170343
Balachandra K; Bowonkiratikachorn P; Poovijit B; Thattiyaphong A; Jayavasu C; Wasi C; Takahashi M; Yamanishi K; Virus Research Institute, Jareonkrungpracharuk Hospital,; Thailand.

Abstract: Of 50 patients in Thailand suspected clinically of having exanthem, subitum, 31 (62%) were serodiagnosed as HHV-6 infection. Sixteen strains of HHV-6 from 31 patients (52%) whose antibody titers had converted during convalescence were isolated during the acute phase. The disease occurred in infants from 3 months to 1 year of age and most frequently at age 4-6 months. Antibody only to HHV-6 converted in 23 of 50 patients (46%), and seroconversion to HHV-6 and dengue virus was observed in 7 patients (14%), and to HHV-6 and Coxsackie B virus in 1 case (2%). In the 23 patients in whom seroconversion only to HHV-6 was observed, all had fever and rash which appeared after subsidence of the fever. Lymphadenopathy and relative lymphocytosis were recognized, associated with diarrhea, vomiting, running nose, cough and hepatomegaly. Febrile convulsions were seen in some cases. All patients recovered completely within a week.
Keywords: Antibodies, Viral/BLOOD Child, Preschool Exanthema Subitum/BLOOD/IMMUNOLOGY/*MICROBIOLOGY Herpesvirus 6, Human/IMMUNOLOGY/*ISOLATION & PURIF Human Infant Thailand JOURNAL ARTICLEKWDantibodies,viral/bloodchild,preschoolexanthemasubitum/blood/immunology/KWDmicrobiologyherpesvirus6,human/immunology/KWDisolation&purifhumaninfantthailandjournalarticle
920630
M9260771

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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