Phenotypic identification of T lymphocytes subset in recurrent aphthous stomatitis.

Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

Phenotypic identification of T lymphocytes subset in recurrent aphthous stomatitis.

Egypt Dent J. 1990 Jan;36(1):33-46. Unique Identifier : AIDSLINE MED/92233819
Abdel All M; Ayoub A; el Refai M; Faculty of Oral and Dental Medicine, Cairo University.

Abstract: Recurrent aphthous stomatitis (RAS) is characterized by recurring ulcers in the oral mucosa as abnormality of the immune response, autoimmune or abnormal immunological reaction to antigens of oral bacteria. This study was conducted on 25 patients 15 suffering RAS of the minor form and 10 of the major form and 15 student as control. The T lymphocytes were determined by the monoclonal antibodies (OKT) using the indirect immunofluorescent technique of Hoffman percentage of cells having surface fluorescence was calculated and the monoclonal antibody coated cells visualized and enumerated. It was concluded from this study that the two clinical entities of RAS may be of the same immunopathologic etiology but the difference lies in the T cell subpopulation and the ratio of T helper to T suppressor T4/T8.

Keywords: Adolescence Adult Antibodies, Monoclonal/DIAGNOSTIC USE CD4-CD8 Ratio Fluorescent Antibody Technique Human Phenotype Stomatitis, Aphthous/*IMMUNOLOGY *T-Lymphocyte Subsets T-Lymphocytes, Helper-Inducer T-Lymphocytes, Suppressor-Effector JOURNAL ARTICLE
920730
M9271071

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