Immunology of the human immunodeficiency virus infection. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Immunology of the human immunodeficiency virus infection.

Tokai J Exp Clin Med. 1990 May;15(2-3):263-7. Unique Identifier : AIDSLINE MED/92023333
Dickmeiss E; Department of Clinical Immunology, State University Hospital,; (Rigshospitalet), Copenhagen, Denmark.

Abstract: From the beginning of the AIDS epidemic it was realized, that the immune system is the major target of the disease. After isolation of the ethiological agent -named the human immunodeficiency virus became clear that there is a dual relationship between the immune system and HIV, i.e. HIV attaques the immune system and the immune system attaques the HIV. The present communication gives a brief review of both aspects of the HIV infection. It is emphasised that both aspects of the relationship have inherent complexities illustrated on the one hand by the findings that the immunodeficiency cannot be explained solely by the established pathogenetic mechanism of lysis of the CD4+ T lymphocytes with ultimate depletion of the cells, and on the other hand by the fact that the virus manage to establish itself as a relentlessly progressing infection in seemingly all infected humans in spite of a vigorous anti-HIV directed immune response.
Keywords: Antibody Formation Antigens, CD/ANALYSIS Human HIV/IMMUNOLOGY HIV Infections/*IMMUNOLOGY Leukocyte Count T-Lymphocytes/IMMUNOLOGY/PATHOLOGY/PHYSIOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL

KWDantibodyformationantigens,cd/analysishumanhiv/immunologyhivinfections/KWDimmunologyleukocytecountt-lymphocytes/immunology/pathology/physiologyjournalarticlereviewreview,tutorial
920130
M9210747

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1992. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1992. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .