Cognitive abnormalities and disease progression in a selected population of asymptomatic HIV-positive subjects. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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Cognitive abnormalities and disease progression in a selected population of asymptomatic HIV-positive subjects.

AIDS. 1991 Sep;5(9):1117-20. Unique Identifier : AIDSLINE MED/92029730
Sinforiani E; Mauri M; Bono G; Muratori S; Alessi E; Minoli L; IIIrd Dept of Neurology, IRCCS C. Mondino, University of Pavia,; Italy.

Abstract: A selected population of 41 homosexual/bisexual asymptomatic HIV-positive subjects were administered neurophysiological tests to assess language, memory, attention, logic faculties and visuo-motor functions. HIV-positive subjects differed from individually matched control subjects only in certain measures of verbal memory. Longitudinal evaluation performed after 1.5 years, however, did not indicate any further development of this mild amnesic deficit. Despite the small number studied in our sample, there seems to be a trend for older subjects to be at greater risk of developing AIDS and cognitive abnormalities than younger subjects, while differences in immunological status play a significant role in disease progression.
Keywords: Adult Analysis of Variance Cognition Disorders/*COMPLICATIONS/IMMUNOLOGY/PSYCHOLOGY Human HIV Infections/COMPLICATIONS/IMMUNOLOGY/*PSYCHOLOGY HIV Seropositivity Longitudinal Studies Male Memory Disorders/*COMPLICATIONS Middle Age Neuropsychological Tests Risk Factors Support, Non-U.S. Gov't JOURNAL ARTICLEKWDadultanalysisofvariancecognitiondisorders/KWDcomplications/immunology/psychologyhumanhivinfections/complications/immunology/KWDpsychologyhivseropositivitylongitudinalstudiesmalememorydisorders/KWDcomplicationsmiddleageneuropsychologicaltestsriskfactorssupport,non-uKWDsKWDgov'tjournalarticle
920228
M9220834

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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