Severe autoimmune hemolytic anemia in SIVsmm9-infected Macaca mulatta. NLM AIDSLINE Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Severe autoimmune hemolytic anemia in SIVsmm9-infected Macaca mulatta.

J Med Primatol. 1991 Jun;20(4):156-8. Unique Identifier : AIDSLINE MED/92045988
Hillyer CD; Brodie AR; Ansari AA; Anderson DC; McClure HM; Emory University Hospital Blood Bank, Department of Pathology and; Laboratory Medicine, Atlanta, GA 30322.

Abstract: One of 15 rhesus macaques infected with SIVsmm9 developed profound hemolysis with spherocytosis, reticulocytosis, and IgG and complement at the red blood cell surface. A female offspring born to this animal developed similar findings. Furthermore, cold agglutinins were noted in samples from both animals. Four of the 13 animals remaining in the cohort had weakly positive antiglobulin tests but were not anemic. Autoimmune hemolytic anemia may be an underrecognized cause of anemia in SIV infection.
Keywords: Anemia, Hemolytic, Autoimmune/*ETIOLOGY Animal Case Report Cohort Studies Female Follow-Up Studies Hematocrit *Macaca mulatta Pregnancy Pregnancy Complications/*ETIOLOGY Pregnancy Complications, Hematologic/ETIOLOGY Pregnancy Complications, Infectious/ETIOLOGY Simian Acquired Immunodeficiency Syndrome/*COMPLICATIONS Support, U.S. Gov't, P.H.S. JOURNAL ARTICLEKWDanemia,hemolytic,autoimmune/KWDetiologyanimalcasereportcohortstudiesfemalefollow-upstudieshematocritKWDmacacamulattapregnancypregnancycomplications/KWDetiologypregnancycomplications,hematologic/etiologypregnancycomplications,infectious/etiologysimianacquiredimmunodeficiencysyndrome/KWDcomplicationssupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
920228
M9220536

Copyright © 1992 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1992. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1992. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .