Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.
ABDOMINAL SURGERY IN PATIENTS WITH AIDS-RELATED LYMPHOMAS (MEETING ABSTRACT)
Proc Annu Meet Am Soc Clin Oncol; 11:A17 1992. Unique Identifier : AIDSLINE ICDB/92680748 Jarrin G; Kemeny M; Lee M; St. Vincent's Medical Center, New York, NY 10011
Abstract:
In a retrospective chart review at St. Vincent's Hospital, 231 cases of non-Hodgkin's lymphoma (NHL) were admitted between 1986 and 1991 and 90 of these pts were known to be HIV antibody-positive. These cases of NHL were predominantly extranodal with 44 pts presenting with abdominal or rectal disease. Of these 44, 16 had an exploratory laparotomy either for diagnosis or treatment. In almost half of the cases (7 pts) the pathology was in the ileocecum or small bowel and the operation was diagnostic as well as therapeutic, eg, repaired bowel perforations, obstructions. Two cases presented as acute cholecystitis with lymphoma found in the gallbladder. Two pts required a partial gastrectomy for bleeding gastric lymphomas. Three pts died within 30 days of operation of rapidly progressive lymphoma. No pt died of operative complications. Operative morbidity was 31% (3 wound infections, 1 pneumonia, 1 prolonged intubation). The predominant cell type was large cell lymphoma (8 pts), followed by immunoblastic (5), and Burkitt's lymphoma (3). There was no significant difference in survival in pts according to their cell type. The overall survival was 3.66 mo. No pt survived longer than 13 mo. Operative mortality and morbidity in our institution was acceptable for this group so we feel an operative approach is necessary to allow for quick treatment to salvage the small number of pts who will benefit from chemotherapy or further treatment.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Burkitt's Lymphoma/ETIOLOGY/PATHOLOGY/SURGERY Gallbladder Neoplasms/*ETIOLOGY/PATHOLOGY/*SURGERY Human Intestinal Neoplasms/*ETIOLOGY/PATHOLOGY/*SURGERY Lymphoma/CLASSIFICATION/*ETIOLOGY/PATHOLOGY/*SURGERY Lymphoma, Large-Cell/ETIOLOGY/PATHOLOGY/SURGERY Lymphoma, Large-Cell, Immunoblastic/ETIOLOGY/PATHOLOGY/SURGERY Lymphoma, Non-Hodgkin's/*ETIOLOGY/PATHOLOGY/*SURGERY Stomach Neoplasms/*ETIOLOGY/PATHOLOGY/*SURGERY ABSTRACT 921230
M92C5376
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