1992

AIDS prevention for laboratory professionals. [videorecording]: Mount Kisco, N.Y. : Guidance Associates ; [Skokie, Ill.] : College of American Pathologists ; [Chicago, Ill.] : American Society of Clinical Pathologists, c1988 1 videocassette (30 min.) : sd., col. ; 1/2 in. + 1 guide (AIDS, everyday precautions for healthcare workers) Unique Identifier : AIDSLINE AV/9200293A; Alpert LI; (Producer) This program illustrates routes by which HIV can--and cannot--be transmitted and describes precautions that will minimize the risk of seroconversion. Proper procedures for working in a lab and performing an autopsy are graphically detailed.
AIDS prevention for nursing professionals. [videorecording]: Mount Kisco, N.Y. : Guidance Associates ; [Skokie, Ill.] : College of American Pathologists ; [Chicago, Ill.] : American Society of Clinical Pathologists, c1988 1 videocassette (30 min.) : sd., col. ; 1/2 in. + 1 guide (AIDS, everyday precautions for healthcare workers) Unique Identifier : AIDSLINE AV/9200294A; Alpert LI; Appel S; (Producer) This program shows how to perform CPR while avoiding dangerous exchange of body fluid and discusses special needs of nurses caring for AIDS patients.
AIDS, HIV, and seroconversion : what you should know. [videorecording]: Mount Kisco, N.Y. : Guidance Associates ; [Skokie, Ill.] : College of American Pathologists ; [Chicago, Ill.] : American Society of Clinical Pathologists, c1988 1 videocassette (30 min.) : sd., col. ; 1/2 in. + 1 guide (AIDS, everyday precautions for healthcare workers) Unique Identifier : AIDSLINE AV/9200295A
AIDS, hepatitis, and the emergency responder. [videorecording]: [Boston, Mass.] : Commonwealth Films ; [Duxbury, Mass.] : D. Lawrence, c1988 1 videocassette (25 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9200378A; Crabtree S
Mending hearts. [videorecording].: Urbana, Ill. : Atlantic Video Works, c1990 1 videocassette (59 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9200358A; Reeve C; Alley J; (Producer) This video documents two years in the lives of four people with HIV who are struggling to come to terms with reality and change their lives to accommodate their diagnosis. The viewer will learn what it is really like to desperately want to live and be happy, yet be faced with the knowledge that death may
Universal precautions : multimedia building blocks for prevention and compliance training. [kit]: [Chicago, Ill.] : The Association, [1991?] 1 manual (1 v., various foliations) Unique Identifier : AIDSLINE AV/9200335A; Buehler JW
GI infections and AIDS. [slide]: [Thorofare, N.J.] : American Gastroenterological Association, c1991 117 slides : col. + 1 guide (AGA clinical teaching project ; unit 6) Unique Identifier : AIDSLINE AV/9200381A; Treadwell TL
Physicians and AIDS : the ethical response. [videorecording]: [United States] : N. Baxley & Associates, c1991 2 videocassettes (53 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9200451A; Bartholome W; Johnson PB; (Producer) Designed to serve as a model for physicians to help them resolve the underlying psychosocial conflicts that may contribute to their reluctance or refusal to provide care to patients with HIV infection. It acknowledges the physicians concerns and provides an incentive for working through them and acceptin
[Sindrom stecene imunodeficitarnosti : virusoloski, imunoloski, klinicki i epidemioloski aspekti.] 1. izd.: Sarajevo : Svjetlost, 1987 188 p. : ill Unique Identifier : AIDSLINE CAT/9202651; Mujagic H
Fifty state survey of state statutes concerning venereal disease as it may relate to AIDS.: Washington, D.C. : Congressional Research Service, Library of Congress, [1987] 13 p Unique Identifier : AIDSLINE CAT/9202788; Wolfe MA
Acquired immune deficiency syndrome : overviews, newspaper editorials, and public opinion polls.: [Washington, D.C. : Congressional Research Service, the Library of Congress, 1987] vi, 105 leaves Unique Identifier : AIDSLINE CAT/9203116; Shaver S; Eddy M
[AIDS-forskning i Danmark, 1987 : en rapport.]: [S.l.] : Forskningsdirektoratet, 1988 153 p. : ill Unique Identifier : AIDSLINE CAT/9202289
[AIDS som juridisk problem.]: [S.l.] : Tano, 1988 110 p Unique Identifier : AIDSLINE CAT/9202288; Hagstrom V
[AIDS i Danmark : den kollegiale vejledning.] 1. udg., 1. opl.: Kobenhavn : Munksgaard, c1988 304 p. : ill Unique Identifier : AIDSLINE CAT/9202287; Ebbesen P
[Omandatud immuunpuudulikkuse sundroom (AIDS).]: Tallinn : Valgus, 1988 Unique Identifier : AIDSLINE CAT/9202561; Roigas E
[AIDS betrifft jeden : medizinische und psychosoziale Aspekte von AIDS im Zusammenhang mit Sexualitat und Tod in unserer Kultur.]: Leibnitz : Bildungshof Retzhof, [1988] 62 p. : ill (Retzhof Schriften. Zur Lebensgestaltung ; Heft 13/1988) Unique Identifier : AIDSLINE CAT/9203075; Arzberger C
[Towarzystwo Lekarskie Czestochowskie : Jubileusz 75-lecia Szpitala Chirurgicznego im. dr Ludwika Rydygiera w Czestochowie.]: Czestochowa : Komitet Organizacyjny Obchodow Jubileuszu 75-lecia Szpitala Chirurgicznego im. dr Ludwika Rydygiera w Czestochowie, 1988 154 p. : ill., ports Unique Identifier : AIDSLINE CAT/9202898; Rudzinski L
[AIDS : das vermeidbare Risiko : Bericht uber Massnahmen gegen die Ausbreitung von AIDS und fur die Versorgung der Betroffenen in Berlin 1987-1989.]: [Berlin, West Germany] : Abgeordnetenhaus von Berlin, [1988] 62 p (Mitteilungen des Prasidenten ; Nr. 297) Unique Identifier : AIDSLINE CAT/9203148
[AIDS-Forum D.A.H.] Bd. 1-: Berlin : Deutsche AIDS-Hilfe e.V., 1988- v. : ill Unique Identifier : AIDSLINE CAT/9202749
AIDS patient registry.: [Washington, D.C.?] : The Office, v Unique Identifier : AIDSLINE CAT/9202946
[AIDS-Nachrichten aus Forschung und Wissenschaft.] 88/1-: und Gesundheit Berlin : Bundesgesundheitsamt, Nationales AIDS-Zentrum, im Auftrag des Bundesministers fur Forschung und Technologie und des Bundesministers fur Jugend, Familie, Frauen und Gesundheit, [1988- v. : ill., ports Unique Identifier : AIDSLINE CAT/9202947
[Dansk AIDS-forskning i 1988 : resume af AIDS-modet, 9. november 1988.]: [S.l] : Forskningsdirektoratet, 1989 20 p Unique Identifier : AIDSLINE CAT/9202341
[Sykepleierens ansvar i hiv- og aidsepidemien.]: Oslo : Universitetsforlaget, c1989 115 p. : ill Unique Identifier : AIDSLINE CAT/9202672; Lid R
Proceedings of the Seminar on AIDS and Psychiatric Nursing Issues : held at, and organized by the Mildura Base Hospital in conjunction with Russell House, 21st June 1989.: [Vic.] : The Group, [1989?] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9202597
AIDS and other sexually transmitted diseases.: Sydney ; Philadelphia : Saunders/Bailliere Tindall, c1989 viii, 186 p. : ill (Current medical reference series) Unique Identifier : AIDSLINE CAT/9203145; Richmond R; Wakefield D
AIDS prevention and education : reframing the message.: New York, NY (121 Sixth Ave., 6th Floor, New York 10013) : Citizens Commission on Aids for New York City and Northern New Jersey, [1989] 80 p Unique Identifier : AIDSLINE CAT/9203146
[Aids und Kommunen : Dokumentation einer gemeinsamen Veranstaltung der kommunalen Spitzenverbande und des Bundesministeriums fur Jugend, Familie, Frauen und Gesundheit, am 19. September 1988 in Bonn.]: und Gesundheit Koln : Deutscher Stadtetag, 1989 90 p (DST-Beitrage zur Sozialpolitik. Reihe D, ISSN 0344-2470 ; Heft 22) Unique Identifier : AIDSLINE CAT/9203122
[Zwischen Angst und Zuwendung : sozialethische und theologische Aspekte von AIDS.] 1. Aufl.: Berlin : Union Verlag, c1989 164 p (Fakten Argumente) Unique Identifier : AIDSLINE CAT/9202924; Neubert E
Caring for someone with AIDS : information for friends, relatives, household members, and others who care for a person with AIDS at home.: [Atlanta, Ga.] : U.S. Dept. of Health and Human Services, Public Health Service, Centers for Disease Control, [1990] [14] p. : ill (America responds to AIDS) Unique Identifier : AIDSLINE CAT/9202315
[Aids-preventie : rol van gemeente en GGD.]: 's Gravenhage : VNG-uitgeverij, [1990?] 43 p. : ill Unique Identifier : AIDSLINE CAT/9202739
HIV infection and the general practitioner.: Melbourne : Royal Australian College of General Practitioners, Family Medicine Programme, 1990 v, 34 p Unique Identifier : AIDSLINE CAT/9202439; Wray L
Processes affecting the spread of HIV infection in Iceland.: North York, Ont., Canada : York University, Atkinson College, 1990 xi, 140 p. : ill (Geographical monographs, ISSN 0829-7622 ; no. 20) Unique Identifier : AIDSLINE CAT/9203504; Haraldsdottir S
The:Crisis in AIDS care : a call to action.: New York, NY (121 Ave. of the Americas, 6th Floor, New York 10013) : Citizens Commission on AIDS for New York City and Northern New Jersey, 1990 printing 99 p Unique Identifier : AIDSLINE CAT/9203233
California HIV/AIDS update. Vol. 3, no. [10/11] (Nov./Dec. 1990)-: Sacramento, CA : The Office, 1990- v. : ill., maps Unique Identifier : AIDSLINE CAT/9202951
AIDS : an overview of issues.: [Washington, D.C.] : Congressional Research Service, Library of Congress, [1991] 13 p (CRS issue brief) Unique Identifier : AIDSLINE CAT/9203147; Johnson JA
AIDS, new challenges in development cooperation : food for thought from a NORAD/NGO workshop on AIDS and development, Oslo, December 1990. 1st ed.: Norway : NORAD, Norwegian Agency for Development Cooperation, 1991 64 p. : port Unique Identifier : AIDSLINE CAT/9203151; Leraand D
Community-based AIDS prevention : studies of intravenous drug users and their sexual partners : proceedings of the First Annual NADR National Meeting.: Meeting Rockville, MD (5600 Fishers Ln., Rockville 20857) : U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Division of Applied Research, Community Research Branch, [1991] ix, 455 p (DHHS publication ; no. (ADM) 91-1752) Unique Identifier : AIDSLINE CAT/9203221
AIDS : is there a will to meet the challenge?.: New York, NY (121 Ave. of the Americas, 6th Floor, New York 10013) : Citizens Commission on AIDS for New York City and Northern New Jersey, [1991] i, 89 p Unique Identifier : AIDSLINE CAT/9203149
Recent advances in sexually transmitted diseases and AIDS. No. 4-: Edinburgh ; New York : Churchill Livingstone, 1991- v. : ill Unique Identifier : AIDSLINE CAT/9202614
The:effects of the AIDS epidemic on traditional Medicaid populations.: Santa Monica, CA : Rand, 1992 xv, 71 p. : ill Unique Identifier : AIDSLINE CAT/9202249; Pascal AH; Research
Challenges of the 1990's, new diseases and new therapies : acquired immunodeficiency syndrome (AIDS) : Merck Sharp & Dohme International, Medical Advisory Council, the Old Course Hotel, St. Andrew's, Scotland, September 12 and 13, 1991.: Philadelphia : Hanley & Belfus, 1992 (MEDAC, Medical Advisory Council ; 1991) Unique Identifier : AIDSLINE CAT/9202764; Luthy R; Douglas RG
The:Neuropathology of HIV infection.: London ; New York : Springer-Verlag, c1993 xvi, 271 p., [3] leaves of plates : ill Unique Identifier : AIDSLINE CAT/9203150; Scaravilli F
TREATMENT OF HPV INFECTION: MANAGEMENT-SURVEILLANCE: Serono Symp Publ Raven; 78:287-90 1990. Unique Identifier : AIDSLINE ICDB/92678077; Contou JF; Cope R; Rothschild Hosp., 33 Boulevard de Picpus, 75571 Paris Cedex 12,; France; The correct therapeutic strategy in genital human papillomavirus (HPV) infection and when and how to employ the various available treatments are open questions. Because of the infectious and sexually transmissible nature of margino-canalar condylomatosis, five principles of venereology should be followed: recognition,
HOMOSEXUAL MEN, SEROPOSITIVITY AND CONDYLOMATOUS INFECTION IN PROCTOLOGY: Serono Symp Publ Raven; 78:295-304 1990. Unique Identifier : AIDSLINE ICDB/92678079; Fenzy A; Doco-Fenzy M; Clavel C; Birembaut P; Medical Group Saint Remi, 22 rue Simon, 51100 Reims, France; Human papillomavirus (HPV)-induced condyloma has been recognized only recently as a sexually transmitted disease (STD). Some HPV condylomata are associated with dysplasia or in situ carcinomas and invasive squamous-cell carcinomas. The authors, in private practice in a town of 230,000 inhabitants in
ANTISENSE OLIGONUCLEOTIDE PHOSPHOROTHIOATES AGAINST HUMAN IMMUNODEFICIENCY VIRUS: Int J Immunotherapy; 6(4):187-91 1990. Unique Identifier : AIDSLINE ICDB/92678554; Zon G; Matsukura M; Applied Biosystems, Inc., 850 Lincoln Centre Dr., Foster City, CA; 94404; Various types of antisense oligonucleotide constructs were synthesized for screening against human immunodeficiency virus (HIV) in two different cell culture assays. Nuclease-resistant internucleoside linkages that were studied included nonionic methyl phosphonates (5 O-P[O]CH3-O3 ) and, primarily, negatively charged
VACCINES AGAINST AIDS: II. VACCINIA EXPRESSING HIV ANTIGENS AS A CANDIDATE VACCINE AGAINST AIDS: New Generation Vaccines. Woodrow GC and Levine MM, eds. New York, Marcel Dekker, p. 753-63, 1990.. Unique Identifier : AIDSLINE ICDB/92678615; Hu SL; Dept. of Virology, ONCOGEN, Seattle, WA; Vaccinia virus has been used successfully for centuries as a vaccination against smallpox. One of the most promising novel approaches to vaccine development involves the use of recombinant vaccinia viruses. Recently, recombinant vaccinia virus has been used to express antigens from a variety of viruses and other micro
ANTITUMOR VACCINES: III. RECOMBINANT VACCINIA VIRUS AS AN APPROACH TO TUMOR IMMUNOTHERAPY: New Generation Vaccines. Woodrow GC and Levine MM, eds. New York, Marcel Dekker, p. 870-7, 1990.. Unique Identifier : AIDSLINE ICDB/92678618; Hu SL; Hellstrom I; Hellstrom KE; Dept. of Virology, ONCOGEN, Seattle, WA; Use of recombinant vaccinia virus in prophylaxis and immunotherapy of neoplastic diseases has important potential advantages, including (1) recombinant vaccinia virus contains a defined tumor antigen, making it easier to obtain specific and reproducible results; (2) the tumor antigen is expressed in the context of vir
PROGRESS IN LYMPHOLOGY--XII: Int Congr Ser; (887):1-623 1990. Unique Identifier : AIDSLINE ICDB/92678737; Anonymous; No affiliation given; The current understanding of the lymph as a fluid containing proteins and migrating cells (eg, macrophages and lymphocytes) has led to treatment of lymphedema based on mechanical external drainage procedures, physiological lympho-venous shunts, and the administration of antibiotics. As the understanding of the lymph i
EPIDEMIOLOGY OF HUMAN T-CELL LEUKEMIA VIRUS TYPE I (HTLV-I): The Human Retroviruses. Gallo RC and Jay G, eds. San Diego, Academic Press, p. 175-92, 1991.. Unique Identifier : AIDSLINE ICDB/92678727; Wiktor SZ; Blattner WA; Viral Epidemiology Section, Environmental Epidemiology Branch,; NCI, Bethesda, MD 20892; Since the discovery of HTLV-I, much has been learned about its epidemiology. Studies have linked the virus with two distinct clinical entities: adult T-cell leukemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic degenerative neurologic syndrome. The epidemiology of HTLV-I is
SYNTHESIS AND ANTIVIRAL EVALUATION OF SUGAR-MODIFIED DERIVATIVES OF THE NUCLEOSIDE ANTIBIOTICS TUBERCIDIN, TOYOCAMYCIN AND SANGIVAMYCIN: Diss Abstr Int [B]; 52(3):1439 1991. Unique Identifier : AIDSLINE ICDB/92679011; Krawczyk SH; Univ. of Michigan; The emergence of the AIDS has been followed by an increase in the incidence of infections due to human cytomegalovirus (HCMV). In our search for new and novel classes of compounds as potential inhibitors of HCMV, we have discovered that a class of compounds known as the pyrrolo (2,
MOLECULAR ANALYSIS OF A NEUROVIRULENT MURINE LEUKEMIA VIRUS, TS1: Diss Abstr Int [B]; 52(3):1228 1991. Unique Identifier : AIDSLINE ICDB/92679043; Szurek PF; Univ. of Texas H.S.C. at Houston Grad. Sch. of Biomed. Sci.; ts1 is a neurovirulent spontaneous temperature-sensitive mutant of Moloney murine leukemia virus TB (MoMuLV-TB). MoMuLV-TB causes T-cell lymphoma or lymphoid leukemia in mice after a long latency period whereas ts1 causes a progressive hindlimb paralytic disease after a much shorter latency period. In previous studies
PERCEPTIONS OF HEALTH BY PERSONS WITH A TERMINAL DISEASE: IMPLICATIONS FOR NURSING: Diss Abstr Int [B]; 52(4):1951 1991. Unique Identifier : AIDSLINE ICDB/92679116; Fryback PB; Univ. of Texas at Austin; A naturalistic study was designed to investigate how people with terminal diseases (cancer/AIDS) describe health. Views of health composed the sensitizing framework which guided the study. A theoretical sampling technique was used to select ten informants: five with cancer and five with AIDS/HIV disease. Five of the p
OPTIMISM, SELF-CONSCIOUSNESS, AND COPING WITH AIDS AND CANCER: Diss Abstr Int [B]; 52(4):2316 1991. Unique Identifier : AIDSLINE ICDB/92679144; Smith KG; Pacific Graduate Sch. of Psychology; Group differences in coping strategies among patients (pts) with chronic, uncontrollable physical disorders were found in Study 1. Iv drug users with AIDS, gay men with AIDS, and advanced-stage cancer pts were all given a multidimensional coping scale (COPE) to assess group differences on fifteen coping strategies. Ov
RADIATION MUCOSITIS IN AIDS: PAST EXPERIENCE AND A NEW PROPOSAL (MEETING ABSTRACT): Br J Cancer; 64(Suppl 15):14 1991. Unique Identifier : AIDSLINE ICDB/92679216; Hughes-Davies LT; Sebag-Montefiore D; Knowles S; Spittle M; Middlesex Hosp., London, UK; The unexpected sensitivity of oropharyngeal mucosa in patients (pts) with AIDS limits the use of radiotherapy in oral Kaposi s sarcoma. We present our experience with 23 pts. Daily fractionation is hazardous. The risk of mucositis appears to increase with time from the AIDS-defining diagnosis. We have recently used we
THE FOURTH WORLD CONGRESS ON CANCERS OF THE SKIN. APRIL 18-20, 1991, NEW YORK, NY: The Fourth World Congress on Cancers of the Skin. April 18-20, 1991, New York, NY, 46 p., 1991.. Unique Identifier : AIDSLINE ICDB/92679312; Anonymous; No affiliation given; The 4th World Congress on Cancers of the Skin, held April 18-20, 1991, in New York City, consisted of presentations with panel discussions, round table workshops, and short presentations on work in progress. The first session addressed viral oncogenesis and skin cancer (overview of human retroviruses, adult T-cell leu
TOTAL SKIN ELECTRON BEAM IRRADIATION FOR CUTANEOUS EPIDEMIC KAPOSI'S SARCOMA (MEETING ABSTRACT): The Fourth World Congress on Cancers of the Skin. April 18-20, 1991, New York, NY, 1991.. Unique Identifier : AIDSLINE ICDB/92679315; DeBlasio DS; Sherr DL; Perry DJ; Bosworth JL; North Shore Univ. Hosp., Manhasset, NY; Epidemic Kaposi s sarcoma (EKS) is a common manifestation of AIDS, and frequently involves multiple, widespread cutaneous sites. Although limited-field radiotherapy has been useful in the management of EKS, the role of total skin electron beam (TSEB) irradiation has never been adequately assessed. Since August 1988, 1
LEUKEMOGENESIS BY TRANSACTIVATING RETROVIRUSES (MEETING ABSTRACT): Seventh International Symposium on Cancer Research of the House of the Hungarian Academy of Sciences: Convergences of International Cancer Research. June 12-14, 1991, Budapest, Hungary, p. 14, 1991.. Unique Identifier : AIDSLINE ICDB/92679643; Burny A; Kettmann R; Willems L; Portetelle D; Voneche V; Callebaut I; van den Broeke A; Mammerickx M; Mornon JP; Brasseur R; Faculty of Agronomy, GEMBLOUX, Belgium; Bovine leukemia virus induces malignant lymphoma in cattle and sheep. In the latter species, 100% of infected animals die in the tumor phase of the disease with a latency inversely correlated to the virus load of the inoculum. Tumor onset is less frequent in infected cattle, due in part to the short economic life-span
IMPROVED SURVIVAL IN ANAL CANAL CANCER WITH COMBINED CHEMOTHERAPY RADIOTHERAPY (MEETING ABSTRACT): Clin Res; 39(3):668A 1991. Unique Identifier : AIDSLINE ICDB/92679840; Grossi CE; Soltani J; Narasimhan P; Gonzalez R; Glasberg S; Friedman D; Dept. of Surgery, LaGuardia Hosp., H.I.P., Forest Hills, NY 11375; The aim was to see if multidisciplinary care changed outcome in anal canal cancer. Treatment modalities and results of anal canal cancer were compared between the periods 1976-1980 and 1981-1990. In these periods there was a total of 23 patients (pts) seen, 7 of them in 1976-1980 and 16 in 1981-1990. HIV infected pts
A NOVEL ZINC FINGER GENE, TZF, PREFERENTIALLY EXPRESSED IN AN HTLV-I-TRANSFORMED T-LYMPHOCYTE LINE, C10 (MEETING ABSTRACT): Clin Res; 39(3):711A 1991. Unique Identifier : AIDSLINE ICDB/92679855; Mayer M; Yang YC; Moore J; Hromas R; Div. of Hematology/Oncology, Indiana Univ. Medical Center,; Indianapolis, IN; The mechanism by which the human T-cell lymphoma/leukemia virus-I (HTLV) transforms T-lymphocytes is not well understood. It is independent of viral genomic insertion, and instead appears to rely on transactivation of undefined cellular growth genes. The targets of this transactivation are of great interest because th
NERVOUS SYSTEM METABOLISM: A MAGNETIC RESONANCE STUDY: Diss Abstr Int [B]; 52(4):1877 1991. Unique Identifier : AIDSLINE ICDB/92679896; Cadoux-Hudson TA; Univ. of Oxford, UK; The aim of this thesis was to investigate the cellular biochemistry and metabolism of the human brain in vivo using magnetic resonance as the basic technique. Magnetic resonance imaging can provide images of human structure and has already proved to be diagnostically useful in Neurology. Magnetic resonance spectroscop
INTRACELLULAR AMPLIFICATION OF THE PROVIRAL DNA OF MOUSE MAMMARY TUMOR VIRUS USING THE POLYMERASE CHAIN REACTION: Diss Abstr Int [B]; 52(3):1232 1991. Unique Identifier : AIDSLINE ICDB/92678997; Chiu K; Univ. of California, Davis; The purpose of this research is to develop a technique for amplifying cellular DNA in situ using the polymerase chain reaction (IS-PCR), which has the potential to be a powerful method for pathogenesis studies. We adopted mouse mammary tumor virus (MMTV) as the model system. MMTV is a retrovirus that induces tumors in
Immunological studies of HTLV-I associated myelopathy.: Autoimmunity. 1988;1(2):125-31. Unique Identifier : AIDSLINE MED/92089470; Kitajima I; Osame M; Izumo S; Igata A; Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima University, Japan.; We report the immunological studies of 50 cases with a chronic progressive myelopathy associated with elevated antibodies to human T-cell lymphotropic virus type I (HTLV-I) and adult T-cell leukemia-like cells (HAM). These are as follows: (1) T-cell activation; (2) increase of the OKT4/OKT8 ratio, due mostly to increa
Animal models for development of an AIDS vaccine.: Int Rev Immunol. 1990;7(1):31-49. Unique Identifier : AIDSLINE MED/92113416; Gardner MB; Department of Medical Pathology, University of California, Davis.
Adjuvants.: Int Rev Immunol. 1990;7(1):51-66. Unique Identifier : AIDSLINE MED/92113417; Edelman R; Tacket CO; Department of Medicine, University of Maryland School of; Medicine, Baltimore 21201.; In summary, HIV vaccine studies described have generally not been designed to measure the effect of the adjuvant or to make comparisons between adjuvants. In only one study was a head-to-head comparison made between HIV antigen alone and antigen formulated with different adjuvants. We hope that future experiments with
Helper independent recombinant adenovirus vectors: expression of HIV env or HBV surface antigen.: Int Rev Immunol. 1990;7(1):67-77. Unique Identifier : AIDSLINE MED/92113418; Chanda PK; Natuk RJ; Dheer SK; Lubeck MD; Bhat BM; Mason BB; Greenberg L; Mizutani S; Davis AR; Hung PP; Biotechnology & Microbiology Division, Wyeth-Ayerst Research,; Philadelphia, Pennsylvania 19101.
Development of a BCG recombinant vehicle for candidate AIDS vaccines.: Int Rev Immunol. 1990;7(1):79-83. Unique Identifier : AIDSLINE MED/92113419; Aldovini A; Young RA; Whitehead Institute for Biomedical Research, Cambridge,; Massachusetts 02142.
The Health Belief Model in the research of AIDS-related preventive behavior.: Public Health Rev. 1990-91;18(1):73-85. Unique Identifier : AIDSLINE MED/92115857; Carmel S; Department of the Sociology of Health, University Center for the; Health Sciences, Ben-Gurion University of the Negev, Beer Sheva,; Israel.; Studies of AIDS-related behavior change which used a systematic psychosocial conceptual model--The Health Belief Model (HBM)--are reviewed. Based on this, it is suggested for further studies: (1) to differentiate among different patterns of potential behavioral change--acceptance of new behaviors, change of existing b
Diagnosis of enzootic bovine leucosis in single and pooled samples.: Rev Sci Tech. 1990 Dec;9(4):1169-73. Unique Identifier : AIDSLINE MED/92096722; Hoff-Jorgensen R; National Veterinary Laboratory V, Copenhagen, Denmark.; Diagnosis of enzootic bovine leucosis is based on detection of antibodies against bovine leukemia virus, BLV. Some ELISA modifications have proved sensitive enough for use in the examination of pooled blood samples from slaughterhouses, milk and pooled milk samples. Suggestions for the standardisation of different ELI
Animal diseases caused by retroviruses: enzootic bovine leukosis, equine infectious anaemia and caprine arthritis-encephalitis.: Rev Sci Tech. 1990 Dec;9(4):983-1119. Unique Identifier : AIDSLINE MED/92096729; Toma B; Eloit M; Savey M; Ecole Nationale Veterinaire d'Alfort, Maisons-Alfort, France.; This article presents the essential features of three retroviral infections of animals: enzootic bovine leukosis, equine infectious anaemia and caprine arthritis-encephalitis. A unique feature of these diseases is persistent infection, maintained throughout the life of the host animal by the presence of a provirus int
Immunology of HIV infection.: Int Rev Immunol. 1990;7(1):1-13. Unique Identifier : AIDSLINE MED/92113413; Lewis DE; Giorgi JV; Department of Microbiology and Immunology, Baylor College of; Medicine, Houston, Texas 77030.; The goal of finding an effective vaccine against the human immunodeficiency virus (HIV) is hampered by our uncertainty of the mechanism(s) responsible for the pathogenesis as well as the lack of knowledge of protective mechanisms. The effects of HIV on the immune system are myriad and thus the truly significant manife
New developments in Sjogren's syndrome.: Curr Opin Rheumatol. 1991 Oct;3(5):815-22. Unique Identifier : AIDSLINE MED/92088843; Moutsopoulos HM; Youinou P; School of Medicine, University of Ioannina, Greece.; Over the past months, noteworthy contributions to our understanding of the clinical manifestations of Sjogren s syndrome have been made. Scintigraphic and echographic techniques have been refined to document xerostomia. Various systemic complications, such as nervous system involvement, pulmonary lesions, gastric and
Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984-87).: Br J Haematol. 1991 Nov;79(3):428-37. Unique Identifier : AIDSLINE MED/92088916; Shimoyama M; Haematology-Oncology and Medical Oncology Division, National; Cancer Center Hospital, Tokyo, Japan.; The following diagnostic criteria are proposed to classify four clinical subtypes of HTLV-1 associated adult T-cell leukaemia-lymphoma (ATL): (1) Smouldering type, 5% or more abnormal lymphocytes of T-cell nature in PB, normal lymphocyte level (less than 4 x 10(9)/l), no hypercalcaemia (corrected calcium level less th
Consistently normal CD4+, CD8+ levels in haemophilic boys only treated with a virally safe factor VIII concentrate (BPL 8Y) [see comments]: Br J Haematol. 1991 Nov;79(3):457-61. Unique Identifier : AIDSLINE MED/92088920; Evans JA; Pasi KJ; Williams MD; Hill FG; Department of Haematology, Children's Hospital, Birmingham.; Prospective biochemical, virological and selected immunological follow up has been done for up to 32 months on 15 previously untreated haemophilic boys following treatment with an intermediate purity dry heated factor VIII concentrate (BPL 8Y). Tests for liver function and antibodies to blood-borne viruses have been a
Soluble HTLV-I Tax1 protein stimulates proliferation of human peripheral blood lymphocytes.: New Biol. 1991 Jul;3(7):678-86. Unique Identifier : AIDSLINE MED/92089024; Marriott SJ; Lindholm PF; Reid RL; Brady JN; Laboratory of Molecular Virology, National Cancer Institute,; Bethesda, MD 20892.; Human T-cell leukemia virus type I (HTLV-I) is associated with two human diseases, adult T-cell leukemia (ATL) and tropical spastic paraparesis/HTLV-I associated myelopathy (TSP/HAM). Lymphocytes from patients with ATL or TSP/HAM display abnormal proliferation properties in culture. Here we report that purified, solub
Ocular myositis as first presenting symptom of human immunodeficiency virus (HIV-1) infection and its response to high-dose cortisone treatment.: Br J Ophthalmol. 1991 Nov;75(11):696-7. Unique Identifier : AIDSLINE MED/92089048; Fabricius EM; Hoegl I; Pfaeffl W; Department of Ophthalmology, Harlaching Hospital, Munchen,; Germany.; A 30-year-old male presented with signs of ocular inflammation and motility disturbances in an early stage of HIV infection. The provisional diagnosis of an ocular myositis was confirmed by orbital echograms. A general check up revealed positive anti-smooth-muscle antibodies and antinuclear antibodies as well as a rai
Herpes simplex keratitis in renal transplant patients [letter; comment]: Br J Ophthalmol. 1991 Nov;75(11):704. Unique Identifier : AIDSLINE MED/92089051; Robin JB
Predictors of HIV-preventive sexual behavior in a high-risk adolescent population: the influence of perceived peer norms and sexual communication on incarcerated adolescents' consistent use of condoms.: J Adolesc Health. 1991 Jul;12(5):385-90. Unique Identifier : AIDSLINE MED/92089109; Diclemente RJ; Center for AIDS Prevention Studies, University of California, San; Francisco 94105.; Data were collected from 112 sexually active adolescents incarcerated in a juvenile detention facility to identify predictors of consistent use of condoms during sexual intercourse. Adolescents completed an anonymous epidemiologic survey instrument developed by the Centers for Disease Control. The self-report survey a
Newsletters respond to AIDS and cancer information overload [news]: Nurse Anesth. 1991 Dec;2(4):201-2. Unique Identifier : AIDSLINE MED/92089213
Treatment of non-Hodgkin's lymphoma.: Curr Opin Oncol. 1991 Oct;3(5):830-7. Unique Identifier : AIDSLINE MED/92089217; Diaz-Pavon JR; Cabanillas F; University of Texas, MD Anderson Cancer Center, Houston.; Many of the advances in the management of non-Hodgkin s lymphomas have been based on more precise understanding of the various cell types that constitute these disorders. During the past year, we have seen some dramatic changes in the therapeutic approach to low-grade lymphomas. Until recently, the usual approach to t
Pathogenesis of HIV-related malignancies.: Curr Opin Oncol. 1991 Oct;3(5):867-71. Unique Identifier : AIDSLINE MED/92089221; Gill PS; University of Southern California School of Medicine, Los; Angeles.; Human immunodeficiency virus (HIV)-1 infection is associated with increased frequency of Kaposi s sarcoma and high-grade B-cell lymphoma. Several other cancers in HIV-1-infected individuals have been reported, although without statistically significant increase in their respective occurrences. Although HIV-1 does not
Cancer in AIDS.: Curr Opin Oncol. 1991 Oct;3(5):955-7. Unique Identifier : AIDSLINE MED/92089230
[The parenteral drug addict in the emergency service]: An Med Interna. 1991 Oct;8(10):477-80. Unique Identifier : AIDSLINE MED/92089387; Lahoz Rallo C; Mostaza Prieto JM; Valencia Ortega ME; Fernandez Martin J; Michan Dona A; Juarez Alonso S; Servicio de Medicina Interna (Seccion Urgencias), Hospital; General La Paz, Madrid.; Clinical and epidemiological features of intravenous drug addicts (IVDA), who attended the emergency department between 1984 and 1988, were studied. The number of cases treated over these 4 years had increased three-fold (256 vs 724). The median age had increased by 3 years (p less than 0.01). The sex ratio had not ch
[Chickenpox and acute pericarditis in a patient with HIV infection (letter)]: An Med Interna. 1991 Oct;8(10):523-4. Unique Identifier : AIDSLINE MED/92089402; Gallego O; Ribera E; Martinez-Vazquez JM
[The incidence and clinical presentation of tuberculosis in HIV-positive patients]: Aten Primaria. 1991 Apr;8(4):310, 312-3. Unique Identifier : AIDSLINE MED/92089413; Jolin Garijo L; Gonzalez Vilas M; Parada Castellano R; Ojea de Castro R; Unidad de Medicina Familiar, Hospital Montecelo, Pontevedra.; To evaluate the features of tuberculous infection in HIV+ patients from our area we reviewed the 50 cases of seropositive patients admitted to a provincial hospital from 1985 to June 1989. TB was diagnosed in 18 of the 50 patients; mean patient age was 27 years, with a male predominance. PDA was the major risk practic
[The Family Medicine Program and AIDS (letter)]: Aten Primaria. 1991 Apr;8(4):350-1. Unique Identifier : AIDSLINE MED/92089426; Thomas Mulet V
Analysis of the fine structure of the antigenic determinants of the transmembrane protein in the HIV coat with chemically modified synthetic peptides.: Biomed Sci. 1991;2(3):271-8. Unique Identifier : AIDSLINE MED/92089499; Andreev SM; Meshcheryakova DB; Vafina MG; Az'muko AA; Sidorova MV; Khaitov RM; Institute of Immunology, Ministry of Health of the USSR, Moscow.; The amino acids involved in IgG reactivity to four HIV-1 gp41 overlapping synthetic peptides from the sequence 584-624 have been determined by a method based on the chemical modification of trifunctional amino acids, especially the acetylation of the amino groups of the lysine residues at pH 8-9. The reactivities of t
HIV-1 gag proteins in virions and in infected cell fractions.: Biomed Sci. 1991;2(3):279-84. Unique Identifier : AIDSLINE MED/92089500; Sharova NK; Grigor'ev VB; Bukrinskaya AG; D I Ivanovskii Institute of Virology, Academy of Medical Sciences; of the USSR, Moscow.; The relation of the initial products of the HIV-1 gag gene to the final products was determined in virus samples and cell fractions of infected H9 and Jurkat-tat cell cultures. The proteins were identified by immunoblotting with pooled sera from AIDS patients or monoclonal antibodies. The proportion in the virions of
Karyological approach to the identification of true cell lines susceptible to the human immunodeficiency virus (HIV).: Biomed Sci. 1991;2(3):293-7. Unique Identifier : AIDSLINE MED/92089503; Glukhova LA; Kiseleva IA; Korneeva MN; Nosik DN; Kushch AA; Mamaeva SE; Ashe B; D I Ivanovskii Institute of Virology, Academy of Medical Sciences; of the USSR, Moscow.; A karyological analysis of twenty-two variants of eight cell lines, which differed in their susceptibility to the human immunodeficiency virus (HIV) and which had been obtained from different sources, was carried out by means of differential chromosome staining for G and C bands. The karyotypes of eight T-lymphoblasto
Region of hepatitis B virus DNA with a homology to the yeast ARS replication enhancer.: Biomed Sci. 1991;2(3):298-301. Unique Identifier : AIDSLINE MED/92089504; Legchilina SP; Efimenko IG; Shlyakhtenko LS; Arman IP; Institute of Molecular Genetics, Academy of Sciences of the USSR,; Moscow.; A computer analysis of the primary sequence of hepatitis B virus (HBV) subtype ayw DNA, cloned within the pVG2 recombinant plasmid, which raises its stability in Saccharomyces cerevisiae transformants, was performed. This revealed that the structure of the HBV DNA has: two bends in the termination regions of the HBs a
Individual-specific patterns of human variable genomic regions detected by a DNA probe from the HIV-1 env gene.: Biomed Sci. 1991;2(3):311-3. Unique Identifier : AIDSLINE MED/92089508; Rogaev EI; Shlenskii AB; Spoode AYa; National Mental Research Centre, Academy of Medical Sciences of; the USSR, Moscow.; It was postulated that similar genetic elements that are hot spots for genetic variation might exist in both the HIV-1 and the human genome. To test this possibility a short repeated sequence from a region of variability in the HIV-1 glycoprotein (env) gene was amplified and used as a probe for blot hybridization wi
Tumor necrosis factor-alpha, interleukin 1, and phorbol myristate acetate are independent activators of NF-kappa B which differentially activate T cells.: Cytokine. 1991 Sep;3(5):372-9. Unique Identifier : AIDSLINE MED/92089516; Krasnow SW; Zhang LQ; Leung KY; Osborn L; Kunkel S; Nabel GJ; Howard Hughes Medical Institute, University of Michigan Medical; Center, Department of Internal Medicine, Ann Arbor 48109-0650.; Gene expression in eukaryotic cells can be altered in different ways by extracellular agents, including mitogens and cytokines. Such differential gene expression is mediated in part through the effects of these stimuli on distinct sets of cellular transcription factors. In this report, the effects of phorbol myristate
HIV and human rights [news]: Br J Addict. 1991 Oct;86(10):1357-8. Unique Identifier : AIDSLINE MED/92089714
HIV infection in London [news]: Br J Addict. 1991 Oct;86(10):1358. Unique Identifier : AIDSLINE MED/92089715
Nutrients as modulators of immune function [letter; comment]: Can Med Assoc J. 1991 Nov 1;145(9):1080-1. Unique Identifier : AIDSLINE MED/92089811; Hegde HR
HIV-1 infection among incarcerated men--Quebec.: Can Dis Wkly Rep. 1991 Oct 26;17(43):233-5. Unique Identifier : AIDSLINE MED/92089921; Hankins C; Gendron S; Handley M; Rouah F; O'Shaughnessy M; Centre for AIDS Studies, Montreal, Quebec.
Tuberculous lymphadenitis In-111 leukocyte and Ga-67 imaging.: Clin Nucl Med. 1991 Nov;16(11):857-8. Unique Identifier : AIDSLINE MED/92090096; Palestro CJ; Swyer AJ; Kim CK; Goldsmith SJ; Department of Physics-Nuclear Medicine, Mt. Sinai School of; Medicine, Mt. Sinai Medical Center, New York, New York.
AIDS prevention and control in China.: Chin Med J (Engl). 1991 Oct;104(10):795-8. Unique Identifier : AIDSLINE MED/92090144; Dai ZC; Department of Epidemic Prevention, Ministry of Public Health,; Beijing.
Immunologic investigation of Chinese hemophiliacs with and without human immunodeficiency virus infection.: Chin Med J (Engl). 1991 Oct;104(10):803-7. Unique Identifier : AIDSLINE MED/92090146; Tang DJ; Pang XG; Institute of Hematology, Zhejiang Medical University, Hangzhou.; Cellular and humoral immune functions in Chinese hemophiliacs with and without human immunodeficiency virus (HIV) infection were compared with those of healthy controls. There was a significant increase in peripheral T8 cells and a significant decrease of peripheral T4 cells as well as the T4/T8 ratio in 3 hemophiliac
Long distance truck-drivers: 1. Prevalence of sexually transmitted diseases (STDs).: East Afr Med J. 1991 Jun;68(6):425-9. Unique Identifier : AIDSLINE MED/92090254; Bwayo JJ; Omari AM; Mutere AN; Jaoko W; Sekkade-Kigondu C; Kreiss J; Plummer FA; Department of Medical Microbiology, College of Health Sciences,; University of Nairobi.; A cross section study was conducted among long distance truck drivers to determine the prevalence of sexually transmitted diseases (STDs) and antibodies to human immunodeficiency virus (HIV). A total of 8 drivers and their assistants en route from port of Mombasa to countries in East and Central Africa were enrolled i
The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function.: Genes Dev. 1991 Dec;5(12B):2496-507. Unique Identifier : AIDSLINE MED/92090728; Southgate CD; Green MR; Program in Molecular Medicine, University of Massachusetts; Medical Center, Worcester 01605.; The Tat protein of human immunodeficiency virus type 1 (HIV-1) activates transcription following binding to nascent trans-activation response (TAR) RNA downstream of the transcription start site. Because Tat functions when bound to RNA, and in a position-dependent manner, it has been proposed that Tat works by a novel
Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpin.: Genes Dev. 1991 Dec;5(12B):2508-20. Unique Identifier : AIDSLINE MED/92090729; Sheline CT; Milocco LH; Jones KA; Salk Institute, La Jolla, California 92037.; Transcriptional activation by the HIV-1 Tat protein requires specific residues in the hexanucleotide loop and trinucleotide bulge of the TAR RNA stem-loop structure found in the 5 -untranslated leader of all viral transcripts. Tat directly contacts residue U22 in the bulge and is thought to act in concert with cellula
[Nosographic profile of thrombocytopenia]: Haematologica. 1991 Jun;76 Suppl 3:109-15. Unique Identifier : AIDSLINE MED/92090811; Mariani G; Iacopino G; Arcieri P; Papacchini M; Dipartimento di Biopatologia Umana, Universita di Roma, La; Sapienza.
[Platelet immunology: diagnostic aspects of thrombocytopenia]: Haematologica. 1991 Jun;76 Suppl 3:116-23. Unique Identifier : AIDSLINE MED/92090813; Borzini P; Centro Trasfusionale e Laboratorio di Ematologia, Monza.
[HIV-positive thrombocytopenia]: Haematologica. 1991 Jun;76 Suppl 3:138-42. Unique Identifier : AIDSLINE MED/92090816; Mezzelani P; Istituto di Clinica Medica, Universita di Verona.
[Epidemiology of the principal hematologic diseases and health needs]: Haematologica. 1991 Jun;76 Suppl 3:223-32. Unique Identifier : AIDSLINE MED/92090833; Caronia F; Malleo C; Divisione di Ematologia, Ospedale V. Cervello, Palermo.
[Transfusion safety]: Haematologica. 1991 Jun;76 Suppl 3:385-94. Unique Identifier : AIDSLINE MED/92090858; Aprili G; Servizio Trasfusionale e di Immunoematologia, Istituti; Ospitalieri, Verona.
[Immunologic changes in polytransfused hemophiliacs]: Haematologica. 1991 Jun;76 Suppl 3:420-3. Unique Identifier : AIDSLINE MED/92090863; Gamba G; Dipartimento di Medicina Interna e Terapia Medica, Universita di; Pavia, IRCCS Policlinico San Matteo.
[Hematologic manifestations of HIV disease]: Haematologica. 1991 Jun;76 Suppl 3:46-50. Unique Identifier : AIDSLINE MED/92090864; Rondanelli EG; Malfitano A; Istituto di Clinica delle Malattie Infettive, Universita degli; Studi di Pavia.
[Discovery of AIDS virus behind the scenes (editorial)]: Harefuah. 1991 Aug;121(3-4):135-6. Unique Identifier : AIDSLINE MED/92090900; Kohn A
Spontaneous monokine release by alveolar macrophages in chronic sarcoidosis.: Int Arch Allergy Appl Immunol. 1991;96(1):68-75. Unique Identifier : AIDSLINE MED/92091091; Strausz J; Mannel DN; Pfeifer S; Borkowski A; Ferlinz R; Muller-Quernheim J; Third Department of Internal Medicine, Johannes Gutenberg; University, Mainz, FRG.; In pulmonary sarcoidosis an activation of alveolar T lymphocytes and alveolar macrophages (AM) has been demonstrated. There is evidence that in contrast to acute disease a heightened T-cell response cannot be observed in the chronic phase of sarcoidosis. The role of AM in the inflammatory process of chronic sarcoidosi
Strongyloidiasis influences the elevation of adult T-cell leukemia-associated antigen antibody titer.: Int Arch Allergy Appl Immunol. 1991;96(1):95-6. Unique Identifier : AIDSLINE MED/92091095; Satoh M; Tsukidate S; Fujita K; Yamamoto K; Department of Medical Zoology, Faculty of Medicine, Tokyo Medical; and Dental University, Japan.; We have carried out a seroepidemiological study on the infectious situation of adult T-cell leukemia and strongyloidiasis in Okinawa and in the south-western islands of Japan . The mean titer of adult T-cell leukemia virus-associated antigen (ATLA) antibody of human T-lymphotropic vi
Cerebral lymphoma and HIV encephalitis in a case of paediatric AIDS, with pre-existing multicystic encephalomalacia.: Ir J Med Sci. 1991 Jun;160(6):179-82. Unique Identifier : AIDSLINE MED/92091144; Keohane C; Robain O; Ponsot G; Gray F; Cork Regional Hospital, Ireland.; A case of intracerebral malignant B cell lymphoma associated with encephalitis typical of Human Immunodeficiency Virus (HIV) infection is described in a 4 year old child, with post-transfusion Acquired Immune Deficiency Syndrome (AIDS) and severe pre-existing cystic encephalomalacia. This report further documents B ce
A genetically engineered protein may hold promise in the fight against the acquired immunodeficiency syndrome (AIDS) [editorial]: J Am Osteopath Assoc. 1991 Nov;91(11):1065. Unique Identifier : AIDSLINE MED/92091184
Congress has passed a compromise bill requiring healthcare workers who perform invasive procedures be tested regularly for the human immunodeficiency virus (HIV) [editorial]: J Am Osteopath Assoc. 1991 Nov;91(11):1070. Unique Identifier : AIDSLINE MED/92091185
Transformation of CD8+ T-cells producing a strong cytopathic effect on CD4+ T-cells through syncytium formation by HTLV-II.: Jpn J Cancer Res. 1991 Nov;82(11):1178-83. Unique Identifier : AIDSLINE MED/92091212; Miyamoto K; Kamiya T; Minowada J; Tomita N; Kitajima K; School of Health Sciences, Okayama University.; Human T-cell leukemia virus type II (HTLV-II) is thought to play an important role in the development of CD8+ T-cell malignancies resembling hairy cell leukemia. In this study, dramatic cytopathic effects characterized by syncytium formation in various CD4+ T-cell lines were observed upon their cocultivation with HTLV
Technological to a fault or faulty approach to technology development?: J Appl Behav Anal. 1991 Fall;24(3):433-5. Unique Identifier : AIDSLINE MED/92091301; Mace FC; University of Pennsylvania.
Visceral leishmaniasis in human immunodeficiency virus disease [letter; comment]: J Clin Pathol. 1991 Nov;44(11):965-6. Unique Identifier : AIDSLINE MED/92091565; Montalban C
Autonomic neuropathy is common in human immunodeficiency virus infection.: J Infect. 1991 Sep;23(2):123-8. Unique Identifier : AIDSLINE MED/92091803; Welby SB; Rogerson SJ; Beeching NJ; Regional Infectious Disease Unit, Fazakerley Hospital, Liverpool,; U.K.; We prospectively evaluated autonomic nervous system function in 17 consecutive ambulant patients with HIV infection [mean age (S.D.) 34.5 (5.5) years] and 17 controls matched for sex and age [31.2 (7.4) years]. A questionnaire was administered, and neurological examination and standard bedside autonomic function tests
AIDS and tuberculosis in Spain. A report of 140 cases.: J Infect. 1991 Sep;23(2):139-44. Unique Identifier : AIDSLINE MED/92091805; Laguna F; Adrados M; Diaz F; Martinez R; Garcia Aguado C; Puente S; Gonzalez Lahoz JM; Service of Infectious Diseases, Instituto de Salud Carlos III,; Madrid, Spain.; From January 1984 to October 1990, 140 of 392 (35.7%) patients with the acquired immunodeficiency syndrome (AIDS) were found to have had tuberculosis. One hundred and sixteen were intravenous drug abusers and 16 were homosexual men. Fever, cough, weight loss and generalised lymphadenopathy were common features of thei
Mycobacterium malmoense infection in HIV positive patients [see comments]: J Infect. 1991 Sep;23(2):191-4. Unique Identifier : AIDSLINE MED/92091814; Claydon EJ; Coker RJ; Harris JR; St Mary's Hospital, Paddington, London, U.K.; Mycobacterium malmoense is a non-tuberculous mycobacterium which has previously been associated with underlying pulmonary pathology and depressed immunity. We describe two patients infected with human immunodeficiency virus from whom M. malmoense was isolated, and discuss its treatment and possible pathogenic role.
Descriptive epidemiology of intravenous heroin users--a new risk group for transmission of HIV in India.: J Infect. 1991 Sep;23(2):201-7. Unique Identifier : AIDSLINE MED/92091817; Sarkar S; Mookerjee P; Roy A; Naik TN; Singh JK; Sharma AR; Singh YI; Singh PK; Tripathy SP; Pal SC; National Institute of Cholera and Enteric Diseases, Calcutta,; India.; India is considered to have a low incidence of HIV infection so far. Nevertheless, an epidemic of HIV infection has been reported recently among intra-venous drug users (IVDUs) in Manipur, a north-eastern state of India, bordering Myanmar (
Mycobacterium haemophilum infection in a patient with AIDS.: J Infect. 1991 Nov;23(3):303-6. Unique Identifier : AIDSLINE MED/92091837; Holton J; Nye P; Miller R; Department of Microbiology, University College and Middlesex; School of Medicine, London, U.K.; We report the isolation of a nutritionally fastidious mycobacterial species, Mycobacterium haemophilum, from the skin of a patient with AIDS. The diagnosis of the mycobacterial nature of the patient s lesions was complicated by extensive Kaposi s sarcoma. It is recommended that slowly growing fastidious mycobacteria b
HTLV-II infection in a Liverpool intravenous drug user [letter]: J Infect. 1991 Nov;23(3):337-9. Unique Identifier : AIDSLINE MED/92091845; Parry CM; Harries AD; Beeching NJ; Shaw IM; Mutton KJ; McAlpine L; Tosswill JH; Tuke PW; Garson JA
Fluconazole resistant candida in AIDS [letter; comment]: J Infect. 1991 Nov;23(3):345-6. Unique Identifier : AIDSLINE MED/92091851; Smith D; Boag F; Midgley J; Gazzard B
Remain true--pride in medicine.: J Ky Med Assoc. 1991 Sep;89(9):439-40. Unique Identifier : AIDSLINE MED/92091936; Nunnelley PP
AIDS in Florida. The first decade.: J Fla Med Assoc. 1991 Oct;78(10):653-4. Unique Identifier : AIDSLINE MED/92091991; Seckinger DL Jr
Infection control.: J Fla Med Assoc. 1991 Oct;78(10):655-7. Unique Identifier : AIDSLINE MED/92091992; Russell B; Infection Control Services, Baptist Hospital of Miami.; Universal precautions and strict infection control procedures have become health-care facility as well as household terms. However, not much time has been given to explaining the specifics of exactly what they are or how and when they should be applied. The purpose, therefore, of this article is to review these specif
Legal considerations. Current Florida law.: J Fla Med Assoc. 1991 Oct;78(10):658-63. Unique Identifier : AIDSLINE MED/92091993; Thrasher JE; Florida Medical Association.; Legislation enacted in 1991 requires physicians licensed under Chapters 458 or 459, Florida Statutes, to earn continuing medical education in the area of HIV and AIDS and specifies what should be covered in the program. The law no longer requires that certain information be imparted to the patient prior to testing for
Management of HIV infection in adults.: J Fla Med Assoc. 1991 Oct;78(10):664-8. Unique Identifier : AIDSLINE MED/92091994; Harrington PT; University of Florida Health Science Center, Jacksonville.; The natural history of HIV infection continues to change with improved diagnostic and therapeutic modalities available to manage opportunistic infections and malignancies. Antiretroviral therapy with zidovudine and other investigational agents has improved the median survival of AIDS patients from 11 months in 1985 to
Epidemiology of AIDS in Florida.: J Fla Med Assoc. 1991 Oct;78(10):669-72. Unique Identifier : AIDSLINE MED/92091995; Witte JJ; Lieb S; Disease Control and AIDS Prevention, Department of Health and; Rehabilitative Services, Tallahassee.; Florida is third in the nation in the cumulative number of AIDS cases. The epidemic in the state has grown steadily since 1981, clustering initially in metropolitan South Florida but dispersing to other urban and nonurban areas. Heterosexually transmitted AIDS is fast increasing and is more than twice as common in Flo
Pediatric HIV infection. An update.: J Fla Med Assoc. 1991 Oct;78(10):673-7. Unique Identifier : AIDSLINE MED/92091996; Sleasman JW; Scott GB; University of Florida College of Medicine, Gainesville.; Human immunodeficiency virus infection is a leading cause of immunodeficiency in children. The epidemic in children parallels that in women since most infected women are in the child-bearing age groups. The risk of vertical transmission of HIV from an infected mother to her infant ranges from 13% to 39%. Diagnosis of
Pathogenesis and natural history of HIV infection.: J Fla Med Assoc. 1991 Oct;78(10):678-81. Unique Identifier : AIDSLINE MED/92091997; Sleasman JW; Goodenow MM; Department of Pediatrics, University of Florida College of; Medicine, Gainesville.; Acquired immune deficiency syndrome (AIDS) is caused by infection with the human immunodeficiency virus (HIV), a human retrovirus. The virus infects cells of the immune system by attachment of a glycoprotein viral envelope (gp 120) to a molecule expressed on human helper T cells called CD4. The fusion of the virus env
Factor influencing suicide intent in gay and bisexual suicide ideators: differing models for men with and without human immunodeficiency virus.: J Pers Soc Psychol. 1991 Nov;61(5):776-88. Unique Identifier : AIDSLINE MED/92092163; Schneider SG; Taylor SE; Hammen C; Kemeny ME; Dudley J; University of California, Los Angeles.; Of 778 gay and bisexual men (none with acquired immunodeficiency syndrome [AIDS]), 27% (n = 212) reported suicidal ideation over the previous 6 months. Covariance structure models were used to explore predictors of suicide intent among (n = 112) suicide ideators with (n = 100) and without (n = 112) human immunodeficie
Postexposure chemoprophylaxis with ZDV or ZDV combined with interferon-alpha: failure after inoculating rhesus monkeys with a high dose of SIV.: J Acquir Immune Defic Syndr. 1991;4(11):1093-7. Unique Identifier : AIDSLINE MED/92092170; Fazely F; Haseltine WA; Rodger RF; Ruprecht RM; Laboratory of Viral Pathogenesis, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115.; Presently, no information is available regarding the efficacy of chemoprophylaxis in controlled human trials following accidental exposure to the human immunodeficiency virus (HIV). Using the closely related simian immunodeficiency virus (SIV) in rhesus monkeys, which develop a disease closely resembling human AIDS, w
Porphyria cutanea tarda in human immunodeficiency virus-seropositive men: case report and literature review.: J Acquir Immune Defic Syndr. 1991;4(11):1112-7. Unique Identifier : AIDSLINE MED/92092173; Cohen PR; Department of Dermatology, University of Texas Medical School,; Houston 77030.; Porphyria cutanea tarda (PCT) is a disorder of heme synthesis characterized by (a) a diminished activity of uroporphyrinogen decarboxylase biochemically and (b) cutaneous lesions secondary to a delayed type of photosensitivity clinically. A human immunodeficiency virus (HIV)-infected patient with PCT is reported and t
Sequential measurement of beta 2-microglobulin levels, p24 antigen levels, and antibody titers following transplantation of a human immunodeficiency virus-infected kidney allograft.: J Acquir Immune Defic Syndr. 1991;4(11):1118-21. Unique Identifier : AIDSLINE MED/92092174; Martin DH; Pearson JE; Kumar P; Kirkendol PL; Leech SH; Gonzalez FM; Saxinger C; Streicher HZ; Department of Medicine, Louisiana State University Medical; Center, New Orleans 70112.; A renal allograft recipient developed symptoms suggestive of AIDS. Serological studies revealed that the donor was positive for human immunodeficiency virus (HIV). Retrospective testing of stored sequential serum samples showed that the recipient was negative for HIV pretransplant; anti-p24 and anti-p41 antibodies app
Association of vitamin B6 status with parameters of immune function in early HIV-1 infection.: J Acquir Immune Defic Syndr. 1991;4(11):1122-32. Unique Identifier : AIDSLINE MED/92092175; Baum MK; Mantero-Atienza E; Shor-Posner G; Fletcher MA; Morgan R; Eisdorfer C; Sauberlich HE; Cornwell PE; Beach RS; Department of Epidemiology and Public Health, University of Miami; School of Medicine, FL 33101.; Nutritional deficiencies have been documented to affect immune function. The present study indicates that vitamin B6 deficiency is prevalent in CDC stage III HIV-1-infected subjects, despite adequate dietary vitamin B6 intake. As vitamin B6 deficiency has been previously shown to affect immune function, these relative
The response of American women to the threat of AIDS and other sexually transmitted diseases.: J Acquir Immune Defic Syndr. 1991;4(11):1133-40. Unique Identifier : AIDSLINE MED/92092176; Campbell AA; Baldwin W; Demographic and Behavioral Sciences Branch, National Institutes; of Child Health and Human Development, Bethesda, Maryland 20892.; Using data from the National Survey of Family Growth, we observe that large numbers of American women say that they are responding to the rising danger of AIDS and other sexually transmitted diseases. Among the changes reported in the 1988 National Survey of Family Growth are use of condoms, sexual relations with fewe
HIV infection and AIDS risk behaviors among intravenous drug users entering methadone treatment in selected U.S. cities.: J Acquir Immune Defic Syndr. 1991;4(11):1148-54. Unique Identifier : AIDSLINE MED/92092178; Battjes RJ; Pickens RW; Amsel Z; National Institute on Drug Abuse, Rockville, MD 20857.; To assess trends in HIV infection and AIDS risk behaviors among intravenous drug users (IVDUs), a series of nonblinded point-prevalence surveys was conducted with admissions to methadone treatment in seven areas, including New York City; Trenton and Asbury Park, New Jersey; Baltimore; Chicago; San Antonio, Texas; and
Risk factors for HIV-2 infection in Guinea-Bissau.: J Acquir Immune Defic Syndr. 1991;4(11):1155-60. Unique Identifier : AIDSLINE MED/92092179; Harrison LH; da Silva AP; Gayle HD; Albino P; George R; Lee-Thomas S; Rayfield MA; Del Castillo F; Heyward WL; Department of International Health, Johns Hopkins University; School of Hygiene and Public Health, Baltimore, Maryland 21205.; To define the epidemiology of HIV-2 infection, we conducted a case-control study among hospitalized patients at an acute care hospital in Bissau, Guinea-Bissau , a country with endemic HIV-2 infection. Among 128 patients with various diagnoses, 23 (18%) were positive for HIV-2 by E
Triple therapy with vinblastine, interferon-alpha 2a and zidovudine for AIDS-related Kaposi's sarcoma [letter]: J Acquir Immune Defic Syndr. 1991;4(11):1161-2. Unique Identifier : AIDSLINE MED/92092180; Borleffs JC; Hoepelman IM; van der Ende ME; van Leusen R; van 't Wout JW
HIV-related autoimmune hemolytic anemia: good response to zidovudine [letter; comment]: J Acquir Immune Defic Syndr. 1991;4(11):1163-4. Unique Identifier : AIDSLINE MED/92092181; Tongol JM; Gounder MP; Butala A; Rabinowitz M
Community-acquired pneumonia with penicillin-resistant pneumococci in a patient with AIDS [letter]: J Acquir Immune Defic Syndr. 1991;4(11):1164. Unique Identifier : AIDSLINE MED/92092182; Istorico LJ; Bradsher RW; Abernathy RS; Vannier A; Martin RE
HIV-1 transmission by a heterosexual man treated with zidovudine [letter]: J Acquir Immune Defic Syndr. 1991;4(11):1166-7. Unique Identifier : AIDSLINE MED/92092185; Routy JP; Blanc AP; Allegre T; Chardon H; Arriodare C
Oral Candida and Enterobacteriaceae in HIV-1 infection: correlation with clinical candidiasis and antimycotic therapy.: J Oral Pathol Med. 1991 Nov;20(10):467-72. Unique Identifier : AIDSLINE MED/92092187; Schmidt-Westhausen A; Schiller RA; Pohle HD; Reichart PA; Abteilung fur zahnarztliche Chirurgie/Oralchirurgie, Nord-Frie; Universitat, Berlin, Germany.; Oral swabs of 73 HIV-1 infected men (32 under conditions of antimycotic treatment (43.8%)) and 58 controls were cultured for Candida species and Enterobacteriaceae. In Group A without antimycotics, yeasts were isolated from 35/41 swabs (85.4%) (range 2 x 10(1) - 4 x 10(6) cfu/ml). In Group B with antimycotics, yeasts
People with AIDS written by a health professional [letter]: J Miss State Med Assoc. 1991 Oct;32(10):376. Unique Identifier : AIDSLINE MED/92092253; Gibson JY
Prevalence of HIV-infection among blood donors.: JPMA J Pak Med Assoc. 1991 Oct;41(10):253-4. Unique Identifier : AIDSLINE MED/92092296; Mujeeb SA; Khanani MR; Khursheed T; Siddiqui A; Blood Transfusion Service, Jinnah Postgraduate Medical Centre,; Karachi.; Blood donor screening for HIV antibody was carried out at Blood Transfusion Service of Jinnah Postgraduate Medical Centre. Sera of 1655 blood donors were tested by Enzyme linked Immuno-Sorbent Assay (Abbott recombinant HIV-1-EIA) from March, 1987 to December, 1989. Initial reactivity was noted in seven cases, of which
Arthritis in rhesus monkeys experimentally infected with simian immunodeficiency virus (SIV/DELTA).: Lab Invest. 1991 Dec;65(6):637-43. Unique Identifier : AIDSLINE MED/92092651; Roberts ED; Martin LN; Delta Regional Primate Research Center, Tulane University,; Covington, Louisiana.; The joint tissues from 36 rhesus (age 2-5 years) infected with SIV/Delta were graded into four groups and then correlated with the following systemic immunologic parameters: numbers of CD4+, CD4+ plus CD29+, and CD20+ cells and SIV/Delta antigenemia. Grade I (n = 16) consisted of normal synovial membrane; grade II (n
Sialoadenitis in experimental graft-versus-host disease. An animal model of Sjogren's syndrome.: Lab Invest. 1991 Dec;65(6):710-8. Unique Identifier : AIDSLINE MED/92092659; Fujiwara K; Sakaguchi N; Watanabe T; Department of Pathology, Saga Medical School, Japan.; Using light microscopic, immunohistochemical, and ultrastructural techniques, we studied sialoadenitis in mice with chronic graft-versus-host disease (GVHD). To induce chronic GVHD, DBA/2 spleen cells were injected into nonirradiated (C57BL/6 x DBA/2)F1 mice. By light and electron microscopy, the submandibular gland l
Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model.: Lab Invest. 1991 Dec;65(6):742-51. Unique Identifier : AIDSLINE MED/92092662; Lamperth L; Dalakas MC; Dagani F; Anderson J; Ferrari R; National Institute of Neurological Disorders and Stroke, National; Institutes of Health, Bethesda, Maryland.; To examine the mechanism of mitochondrial myocytotoxicity caused by long-term administration of zidovudine ( AZT ) in human immunodeficiency virus-positive patients, we examined the effect of AZT in vitro on human muscle in tissue culture and in vivo in
[The evidence of human immunodeficiency virus infection in the seronegative subjects of high-risk groups]: Med Clin (Barc). 1991 Oct 12;97(12):441-5. Unique Identifier : AIDSLINE MED/92092789; Soriano V; Hewlett I; Tor J; Esteve M; Granada I; Muga R; Epstein J; Medrano L; Unidad de Enfermedades Infecciosas, Hospital Germans Trias i; Pujol, Badalona, Barcelona.; BACKGROUND: Polymerase chain reaction (PCR) is a new diagnostic procedure which has been used to recognise HIV-infected individuals who remain seronegatives. METHODS: Genomic DNA isolated from the peripheral blood mononuclear cells of 90 high-risk individuals were analyzed by PCR using gag primers SK 38/39. Subjects w
[The mycoplasmas isolated from respiratory specimens]: Med Clin (Barc). 1991 Oct 12;97(12):449-52. Unique Identifier : AIDSLINE MED/92092791; Ferreruela RM; Farga MA; Alcaraz MJ; Garcia de Lomas J; Departamento de Microbiologia, Facultad de Medicina, Hospital; Clinico Universitario, Valencia.; BACKGROUND: Mycoplasma pneumoniae is the species that is considered pathogen for respiratory tract. Other species, M. hominis and U. urealyticum, have been isolated from respiratory specimens and its aetiological relation with respiratory infections is not clear. METHODS: In this study, mycoplasma from respiratory spe
[Paraproteinemias in patients infected with the human immunodeficiency virus (letter)]: Med Clin (Barc). 1991 Oct 12;97(12):475-6. Unique Identifier : AIDSLINE MED/92092801; Perez-Hurtado JM; Pachon J; Fernandez-Gonzalez G; Viciana P
[Visceral leishmaniasis with partial response to ketoconazole in a patient with positive antibodies to the human immunodeficiency virus (letter) (published erratum appears in Med Clin (Barc) 1991 Dec 7;97(20):48)]: Med Clin (Barc). 1991 Oct 12;97(12):476-7. Unique Identifier : AIDSLINE MED/92092803; Andreo JA; Vivancos F; Serrano P; Soriano J
[The effect of inhaled pentamidine in the radiology of Pneumocystis carinii pneumonia (letter)]: Med Clin (Barc). 1991 Oct 12;97(12):477-8. Unique Identifier : AIDSLINE MED/92092804; Pomes J; Miro JM; Spala J; Mallolas J
[Peripheral facial paralysis and HIV infection]: Minerva Stomatol. 1991 Jul-Aug;40(7-8):495-8. Unique Identifier : AIDSLINE MED/92092936; Piluso S; Ficarra G; Gaglioti D; Pierleoni F; Istituto di Odonto-Gnato-Stomatologia, Universita di Firenze.; Two cases of peripheral facial paralysis associated with infection by the human immunodeficiency virus in young intravenous drug abuser patients are reported. One patient manifested AIDS-related complex (ARC) and the other fulfilled the Center for Disease Control (CDC) criteria for AIDS. Clinical symptoms and signs oc
AIDS and surrogate decision making.: Mt Sinai J Med. 1991 Oct;58(5):375-8. Unique Identifier : AIDSLINE MED/92093011; Hansell DA; Legal Services Department, Gay Men's Health Crisis, New York, NY; 10011.
Foster parents as surrogates for infants and young children.: Mt Sinai J Med. 1991 Oct;58(5):393-7; discussion 398-402. Unique Identifier : AIDSLINE MED/92093017; Moreno JD; Department of Pediatrics and Medicine, SUNY Health Science; Center, Brooklyn 11203-2098.
The epidemiology of cocaine use in New York State.: Mt Sinai J Med. 1991 Oct;58(5):406-11; discussion 437-42. Unique Identifier : AIDSLINE MED/92093019; Frank B; Des Jarlais DC; Marel R; Schmeidler J; Maranda M; New York State Division of Substance Abuse Services, New York; 10027.
Drug policy in New York City.: Mt Sinai J Med. 1991 Oct;58(5):421-2; discussion 437-42. Unique Identifier : AIDSLINE MED/92093022; Joseph SC; Department of Health, New York City.
HIV infection in drug abusers: research implications of descriptive studies.: NIDA Res Monogr. 1991;109:101-13. Unique Identifier : AIDSLINE MED/92093056; Dorus W; Schaefer M; Pachucki CT; Schaaff DM; Lentino JR; Substance Abuse Treatment Program, Edward Hines, Jr. Hospital,; Department of Veterans Affairs, Hines, IL 60141.
Potential cofactors in the outcomes of HIV infection in intravenous drug users.: NIDA Res Monogr. 1991;109:115-23. Unique Identifier : AIDSLINE MED/92093057; Des Jarlais DC; Beth Israel Medical Center, New York, New York.
How can results of longitudinal studies help mathematicians model the HIV epidemic among intravenous drug abusers and the general population?: NIDA Res Monogr. 1991;109:125-44. Unique Identifier : AIDSLINE MED/92093058; Cooley PC; Hamill DN; Reade-Christopher SJ; Liner EC; van der Horst CM; Center for Computer Science, Research Triangle Institute,; Research Triangle Park, NC 27709.
Natural history of HIV infection in gay men and intravenous drug users.: NIDA Res Monogr. 1991;109:29-50. Unique Identifier : AIDSLINE MED/92093059; Friedland G; Albert Einstein College of Medicine, Bronx, New York.
Sampling issues for natural history studies including intravenous drug abusers.: NIDA Res Monogr. 1991;109:51-62. Unique Identifier : AIDSLINE MED/92093060; Wiebel WW; AIDS Outreach Intervention Program, School of Public Health,; University of Illinois, Chicago 60612.
Toward comprehensive studies of HIV in intravenous drug users: issues in treatment-based and street-based samples.: NIDA Res Monogr. 1991;109:63-73. Unique Identifier : AIDSLINE MED/92093061; Watters JK; Cheng YT; Department of Epidemiology and Biostatistics, School of Medicine,; University of California, San Francisco.
Strategies for enhancing existing studies of the natural history of HIV-1 infection among drug users.: NIDA Res Monogr. 1991;109:9-28. Unique Identifier : AIDSLINE MED/92093063; Chitwood DD; Comerford M; Trapido EJ; Sylvester Comprehensive Cancer Center, University of Miami School; of Medicine, FL 33136.
AIDS: advocacy and activism.: Nurs Health Care. 1991 Dec;12(10):515. Unique Identifier : AIDSLINE MED/92093242; Fedor MA
Do nursing students need AIDS education?: Nurse Educ. 1991 Nov-Dec;16(6):34-5. Unique Identifier : AIDSLINE MED/92093260; Carroll JL
Counseling to avoid AIDS.: Pa Med. 1991 Oct;94(10):30-2. Unique Identifier : AIDSLINE MED/92093414; Pazin GJ; University of Pittsburgh, School of Medicine.
Automated assembly of protein blocks for database searching.: Nucleic Acids Res. 1991 Dec 11;19(23):6565-72. Unique Identifier : AIDSLINE MED/92093619; Henikoff S; Henikoff JG; Howard Hughes Medical Institute, Fred Hutchinson Cancer Research; Center, Seattle, WA 98104.; A system is described for finding and assembling the most highly conserved regions of related proteins for database searching. First, an automated version of Smith s algorithm for finding motifs is used for sensitive detection of multiple local alignments. Next, the local alignments are converted to blocks and the bes
Double prejudice [news]: Nurs Times. 1991 Nov 20-26;87(47):21. Unique Identifier : AIDSLINE MED/92093675; Gaze H
More research needed to help women with HIV [news]: Nurs Times. 1991 Nov 27-Dec 3;87(48):6. Unique Identifier : AIDSLINE MED/92093708; Snell J
[Tuberculosis in the United States (review of foreign literature 1983-1989)]: Probl Tuberk. 1991;(7):71-3. Unique Identifier : AIDSLINE MED/92093976; Priimak AA; Kucherov AL; Smirnova LV; Bogdanova NB
Delivery of topical antibiotics: pharmacokinetics and clinical problems.: Semin Respir Infect. 1991 Sep;6(3):158-67. Unique Identifier : AIDSLINE MED/92094202; Ilowite JS; Niederman MS; Fein AM; Pulmonary and Critical Care Medicine Division,; Winthrop-University Hospital, Mineola, NY 11501.; Despite major advances in new therapeutic agents to treat pneumonia, pneumonia remains a major cause of morbidity and mortality in hospitalized patients. Topical antibiotics offer many potential advantages in the treatment and prevention of nosocomial pneumonia. These include a high delivery of the drug to the site of
Psychological symptoms and behavioural changes in Finns caused by fear of AIDS.: Scand J Prim Health Care. 1991 Sep;9(3):187-90. Unique Identifier : AIDSLINE MED/92094218; Viinamaki H; Tikkanen J; Koskela K; Department of Psychiatry, Kuopio University Hospital, Finland.; The purpose of the study was to explore personal fears about AIDS and their consequences in terms of psychological symptoms and behaviour. 1902 individuals, 15 to 64 years old, were selected at random from the Finnish population and interviewed by telephone (94%) or in person (6%). 2.5% regarded AIDS as a personal thr
Pathogenesis of SLE: immunopathology in man.: Rheumatol Int. 1991;11(3):95-100. Unique Identifier : AIDSLINE MED/92094291; Kalden JR; Winkler TH; Herrmann M; Krapf F; Department of Medicine III, University Erlangen-Nurnberg,; Federal Republic of Germany.; Antibodies against native DNA are not only a disease-specific marker for systemic lupus erythematosus (SLE); in addition, there is good direct evidence that these antibodies also play a major part in pathogenic mechanisms leading to systemic and organ-specific disease manifestations. The origin of anti-dsDNA antibodie
Cross reaction. Could AIDS really be an autoimmune disease? [news]: Sci Am. 1991 Dec;265(6):56-7. Unique Identifier : AIDSLINE MED/92094350; Beardsley T
Confronting the lack of resources for patients with AIDS dementia complex.: Soc Work. 1991 Nov;36(6):473-5. Unique Identifier : AIDSLINE MED/92094444; Lee KC; McGill C; Alta Bates Herrick Hospital, Berkeley, CA 94704.
Stimulation of natural killer cell activity by murine retroviral infection and cocaine.: Toxicol Lett. 1991 Dec;59(1-3):147-52. Unique Identifier : AIDSLINE MED/92094596; Poet TS; Pillai R; Wood S; Watson RR; Department of Pharmacology and Toxicology, University of Arizona,; Tucson.; The effects of cocaine and murine AIDS on natural killer (NK) cell activity in C57BL/6 mice was studied. Cocaine may play a major role in the development and progression to AIDS in the human population. Chronic intraperitoneal injection of cocaine was shown to cause an increase in NK cell activity over those of saline
Confidential unit exclusion: how should it be evaluated? [letter; comment]: Transfusion. 1991 Nov-Dec;31(9):869-71. Unique Identifier : AIDSLINE MED/92094676; Petersen LR; Busch MP
The CUE debate (continued): on surrogate tests and surrogate endpoints [letter; comment]: Transfusion. 1991 Nov-Dec;31(9):869, 870-1. Unique Identifier : AIDSLINE MED/92094677; Busch MP; Perkins HA; Holland P; Petersen L
Age is no bar to sexually acquired infection.: Age Ageing. 1991 Sep;20(5):377-8. Unique Identifier : AIDSLINE MED/92095184; Rogstad KE; Bignell CJ; Department of Genito-Urinary Medicine, City Hospital, Nottingham.; Two hundred and forty-two patients aged 60 years or over attended genito-urinary clinics in Nottingham and Leicester (England) in a 2-year period. Sixty-nine per cent of men and 53% of women were sexually active and 58 were found to have sexually transmitted diseases.
Pandemonium over gloves: use and abuse [editorial]: Am J Infect Control. 1991 Oct;19(5):225-7. Unique Identifier : AIDSLINE MED/92095497; DeGroot-Kosolcharoen J
[Bone marrow changes at several stages of HIV infection, studied on bone marrow biopsies in 85 patients]: Arch Anat Cytol Pathol. 1991;39(4):137-46. Unique Identifier : AIDSLINE MED/92095683; Diebold J; Tabbara W; Marche C; Audouin J; Le Tourneau A; Service Central Jacques Delarue d'Anatomie et de Cytologie; Pathologiques, Hotel-Dieu, Notre-Dame, Paris.; Bone marrow biopsies from eighty-five patients with different stages of HIV infection were reviewed. Biopsies were generally indicated to evaluate peripheral blood abnormalities, but suspicion of lymphoma and other specific pathologies was another important indication. The histopathological features are described and
[AIDS center--hospitals--nursing homes (news)]: TVZ. 1991 Oct 10;(19):678. Unique Identifier : AIDSLINE MED/92096125
Cytokines in viral diseases.: Curr Opin Immunol. 1991 Aug;3(4):486-91. Unique Identifier : AIDSLINE MED/92096140; Campbell IL; Scipps Research Institute, La Jolla, California.; As in many other areas of cytokine biology, recent studies of the role of cytokines in viral disease reveal numerous complex interactions that in many instances may contribute directly to the development of pathology. For example, data from the rapidly evolving field of human retrovirology has shown that these viruses
Control of human immunodeficiency virus replication by the tat, rev, nef and protease genes.: Curr Opin Immunol. 1991 Aug;3(4):526-36. Unique Identifier : AIDSLINE MED/92096147; Karn J; MRC Laboratory of Molecular Biology, Cambridge, UK.; Immediately after infection, human immunodeficiency virus directs the synthesis of three regulatory proteins tat, rev and nef that together allow the synthesis of the structural proteins of the virus after a delay of several hours. Viral mRNA production is controlled by the tat gene, which appears to stimulate elongat
HIV types and testing.: Curr Opin Immunol. 1991 Aug;3(4):543-6. Unique Identifier : AIDSLINE MED/92096149; Dalgleish AG; London Hospital Medical College, UK.; The past year has seen the discovery of new isolates which do not readily fit into the established categories HIV-1, HIV-2 and SIV, as well as the availability of new assays including the use of the polymerase chain reaction. New combination enzyme-linked immunosorbent assays can detect viruses from two or more groups
Immunodeficiency.: Curr Opin Immunol. 1991 Aug;3(4):611-42. Unique Identifier : AIDSLINE MED/92096154
Acquired immunodeficiency syndrome (AIDS). The STD/AIDS control programme.: Wkly Epidemiol Rec. 1991 Dec 6;66(49):361-4. Unique Identifier : AIDSLINE MED/92096363
The use of video tape in teaching how psychological factors influence nutritional status in chronic/terminal illness.: J Cancer Educ. 1991;6(4):213-7. Unique Identifier : AIDSLINE MED/92096367; LeGardeur BY; Fe-Bornstein M; Lopez A; Department of Medicine, Louisiana State University School of; Medicine, New Orleans 70112.; The medical students of Louisiana State University Medical School in New Orleans are required to take a clinical nutrition course in their senior year. In 1989, audio-visual media were used to introduce the students to the ways that the psychological aspects of chronic/terminal illness can influence nutritional status
Impaired in vitro growth of peripheral blood hematopoietic progenitor cells in HIV-infected patients: evidence of an inhibitory effect of autologous T lymphocytes.: Ann Hematol. 1991 Dec;63(6):320-5. Unique Identifier : AIDSLINE MED/92096496; Balleari E; Timitilli S; Puppo F; Gaffuri L; Musselli C; Rizzo F; Indiveri F; Ghio R; Department of Internal Medicine, University of Genova, Italy.; The in vitro growth of both circulating granulocyte-macrophage (CFU-GM) and erythroid (BFU-E) progenitor cells was assessed in 29 individuals infected with the human immunodeficiency virus (HIV) at different stages of infection. The effects of autologous T lymphocytes, adherent cells, and serum on the in vitro growth
Nosocomial tuberculosis in the AIDS era: strategies for interrupting transmission in developed countries.: Bull Int Union Tuberc Lung Dis. 1991 Jun-Sep;66(2-3):107-11. Unique Identifier : AIDSLINE MED/92096731; Nardell EA; Cambridge Hospital, Harvard Medical School, Massachusetts; Department of Public Health.; In developed countries where tuberculosis is increasing in association with HIV infection, nosocomial transmission among patients and from patients to health care workers is being increasingly reported. Nosocomial tuberculosis among HIV-infected patients is difficult to prevent by conventional control measures because
[Oral and parenteral immunization with HIV immunosome induce the secretion of IgA specific of HIV-1 in the salivary and the production of circulatory IgA in mice and rabbits]: C R Acad Sci III. 1991;313(9):389-94. Unique Identifier : AIDSLINE MED/92096875; Thibodeau L; Tremblay C; Lachapelle L; Institut Armand-Frappier, Universite du Quebec, Laval, Canada.; Given the sexual transmission of HIV, the establishment of a genital mucosal immunity through secretory IgA may be necessary to achieve protection. We have investigated if repeated stimulations of oral mucosa with HIV-Immunosomes would lead to the production of secretory IgA in saliva and also, if such an oral immuniz
Musculoskeletal disorders in the haemophilias.: Baillieres Clin Rheumatol. 1991 Aug;5(2):197-220. Unique Identifier : AIDSLINE MED/92097212; York JR; The management of the haemophilias has been improved by the advent of potent consistent clotting factor replacement therapy. The previously lethal major complications such as intracerebral haemorrhage are now rare, and the infective complications of treatment, most notably hepatitis and AIDS, are now potentially preve
[Cryptococcal meningitis in AIDS: successful long-term prophylaxis with fluconazole]: Dtsch Med Wochenschr. 1991 Dec 20;116(51-52):1955-8. Unique Identifier : AIDSLINE MED/92097487; Gluck T; Weber P; Wiedmann KH; Abteilung Innere Medizin I, Medizinische Universitatsklinik; Tubingen.; A 30-year-old, HIV-positive, man who had been repeatedly treated with amphotericin B for oral thrush , developed headaches, fever up to 38.5 degrees C, dizzy spells with falling tendency, as well as disorder of speech and word finding. Cerebrospinal fluid (CSF) contained 5700/3
[Pneumothorax in AIDS]: Dtsch Med Wochenschr. 1991 Dec 20;116(51-52):1981. Unique Identifier : AIDSLINE MED/92097493
HIV-1 Tat protein promotes formation of more-processive elongation complexes.: EMBO J. 1991 Dec;10(13):4189-96. Unique Identifier : AIDSLINE MED/92097539; Marciniak RA; Sharp PA; Center for Cancer Research, Massachusetts Institute of; Technology, Cambridge 02139.; The Tat protein of HIV-1 trans-activates transcription in vitro in a cell-free extract of HeLa nuclei. Quantitative analysis of the efficiency of elongation revealed that a majority of the elongation complexes generated by the HIV-1 promoter were not highly processive and terminated within the first 500 nucleotides. T
Expression of heterologous genes in Mycobacterium bovis BCG: induction of a cellular response against HIV-1 Nef protein.: Gene. 1991 Dec 20;109(1):47-54. Unique Identifier : AIDSLINE MED/92097951; Winter N; Lagranderie M; Rauzier J; Timm J; Leclerc C; Guy B; Kieny MP; Gheorghiu M; Gicquel B; Unite de Genie Microbiologique, C.N.R.S. URA 1300, Institut; Pasteur, Paris, France.; Mycobacterium bovis bacillus Calmette-Guerin (BCG) has been used as a live bacterial vaccine to immunize more than two billion people against tuberculosis. In an attempt to use this vaccinal strain as a vehicle for protective antigens, the human immunodeficiency virus type 1 gene encoding the Nef protein was cloned in
Inhibition of human immunodeficiency virus infection in monocytes by monoclonal antibodies against leukocyte adhesion molecules.: Immunol Lett. 1991 Oct;30(2):219-27. Unique Identifier : AIDSLINE MED/92098118; Kalter DC; Gendelman HE; Meltzer MS; Department of Cellular Immunology, Walter Reed Army Institute of; Research, Washington, DC.; CD4 is the surface receptor for HIV envelope. Some evidence exists, however, that other cell surface receptors may be involved in viral entry subsequent to the initial binding of gp120 to CD4. Antibodies to leukocyte integrin LFA-1, a major component of intercellular adhesive interactions, have been shown to inhibit H
Outcomes of an AIDS prevention program for methadone patients.: Int J Addict. 1991 Jun;26(6):629-55. Unique Identifier : AIDSLINE MED/92098226; Magura S; Siddiqi Q; Shapiro J; Grossman JI; Lipton DS; Marion IJ; Weisenfeld L; Amann KR; Koger J; Narcotic and Drug Research, Inc., New York, New York 10013.; Methadone maintenance patients are at risk of contracting or transmitting HIV through intravenous drug use and/or unsafe sexual practices. An outcome evaluation of a voluntary AIDS prevention program for methadone patients in three clinics (two experimental, one control) is reported. The prevention program included th
Characterization of circulating lymphocytes by monoclonal antibodies in childhood and adult leprosy.: Int J Dermatol. 1991 Nov;30(11):780-4. Unique Identifier : AIDSLINE MED/92098239; Sehgal VN; Chaudhry A; Sharma VK; Gupta CK; Department of Dermatology and Venereology, Maulana Azad Medical; College, Associated LNJPN Hospital, New Delhi, India.; Peripheral blood lymphocyte assays using monoclonal antibodies were done in 66 patients with leprosy, consisting of 25 children and 41 adults. The results were statistically analyzed for correlations, if any, among the different age groups and matched controls. The results, however, failed to show any significant corr
Papular pruritic eruption with human immunodeficiency virus infection.: Int J Dermatol. 1991 Nov;30(11):801-3. Unique Identifier : AIDSLINE MED/92098244; Banuls J; Ramon D; Aniz E; Jorda E; Torres V; Service of Dermatology, Valencia Clinic Hospital, Spain.
Cutaneous nocardiosis and human immunodeficiency virus infection.: Int J Dermatol. 1991 Nov;30(11):804-5. Unique Identifier : AIDSLINE MED/92098245; Boixeda P; Espana A; Suarez J; Buzon L; Ledo A; Department of Dermatology, Hospital Ramon y Cajal, Madrid, Spain.
Using the health belief model to predict safer sex intentions among adolescents.: Health Educ Q. 1991 Winter;18(4):463-76. Unique Identifier : AIDSLINE MED/92098341; Petosa R; Jackson K; Department of Health Education, Ohio State University, Columbus; 43210.; The purpose of this study was to use Health Belief Model (HBM) concepts to predict adolescents intentions to adopt safer sex behaviors. A stratified, random sampling technique was used to generate a sample of seventh-, ninth-, and eleventh-grade students representative of a southeastern state. A predictive model was c
Cytokine induction in HTLV-I associated myelopathy and adult T-cell leukemia: alternate molecular mechanisms underlying retroviral pathogenesis.: J Cell Biochem. 1991 Aug;46(4):302-11. Unique Identifier : AIDSLINE MED/92098593; Tendler CL; Greenberg SJ; Burton JD; Danielpour D; Kim SJ; Blattner WA; Manns A; Waldmann TA; Metabolism Branch, National Cancer Institute, National Institutes; of Health, Bethesda, Maryland 20892.; The human T-cell lymphotropic virus type I (HTLV-I) is capable of inducing a variety of host cellular genes including many of the cytokines responsible for immune regulation and osteoclast activation. This derangement in cytokine expression may contribute to the panoply of disease states associated with HTLV-I infecti
Mycobacterium avium complex disease in patients with AIDS: seroreactivity to native and recombinant mycobacterial antigens.: J Clin Microbiol. 1991 Dec;29(12):2715-9. Unique Identifier : AIDSLINE MED/92098679; Morris SL; Bermudez L; Chaparas SD; Center for Biologics Evaluation and Research, Food and Drug; Administration, Bethesda, Maryland 20892.; Antibodies to Mycobacterium avium complex (MAC) antigens were measured by enzyme-linked immunosorbent assays and immunoblot analyses in sera from 20 patients with AIDS and disseminated MAC disease, 5 human immunodeficiency virus-seronegative patients with pulmonary MAC infections, and 20 healthy controls. Whereas enzy
Radical reflection as a theoretical framework in nursing using acquired immunodeficiency syndrome as example.: J Prof Nurs. 1991 Sep-Oct;7(5):283-92. Unique Identifier : AIDSLINE MED/92098888; Kendall J; Roddy A; Georgia State University, Atlanta.; The purpose of this article is to present a critical theoretical analysis of society s view of the acquired immunodeficiency syndrome (AIDS) epidemic. The method of radical reflection that was developed by Jan Thompson in 1983 is used as the framework of analysis. Through the five steps of Thompson s method (bracketin
AIDS and homophobia among nurses.: J Homosex. 1991;21(4):17-27. Unique Identifier : AIDSLINE MED/92098924; Scherer YK; Wu YW; Haughey BP; School of Nursing, State University of New York, Buffalo, NY; 14214.; The purpose of this research was to study nurses attitudes toward homosexuality and caring for homosexual patients. The results reported in this article are a component of a larger study of nurses knowledge about and attitudes toward caring for patients with AIDS. The sample comprised 581 Registered Nurses residing
Astrogliosis in von Economo's and postencephalitic Parkinson's diseases supports probable viral etiology.: J Neurol Sci. 1991 Oct;105(2):131-4. Unique Identifier : AIDSLINE MED/92099078; Elizan TS; Casals J; Department of Neurology, Mount Sinai School of Medicine City; University of New York, NY 10029.; A marked generalized astrogliosis was observed in the frontal and temporal white matter from a case of von Economo s disease and another of postencephalitic Parkinson s disease, which areas were otherwise devoid of any other demonstrable microscopic lesions. No similar astrocytic reaction of any severity was observed
HIV-seropositive childbearing women. Nursing management.: J Obstet Gynecol Neonatal Nurs. 1991 Nov-Dec;20(6):446-52. Unique Identifier : AIDSLINE MED/92099122; Jones DA; Perinatal Unit, Southern Hills Medical Center, Nashville,; Tennessee.; With the implementation of the recommendation of the American College of Obstetricians and Gynecologists to screen all women who are at increased risk for HIV infection, more asymptomatic infected women will be identified. Obstetric and neonatal nurses who learn more about maternal and infant HIV infection can determi
HIV seroprevalence in Oklahoma childbearing women.: J Okla State Med Assoc. 1991 Nov;84(11):566-9. Unique Identifier : AIDSLINE MED/92099130; Govin M; Botchlet R; Graves T; Harkess J; Kudlac J; AIDS Division, Oklahoma State Department of Health, Oklahoma City; 73117-1299.; From October 1989 through September 1990, we conducted an unlinked seroprevalence survey in Oklahoma to determine the prevalence of human immunodeficiency virus, type 1 (HIV) in women at the time of childbirth. Blood specimens obtained from 41,809 newborns in conjunction with the state s newborn metabolic screening pr
Epidemiology of sharps accidents in general surgery.: J R Coll Surg Edinb. 1991 Oct;36(5):314-6. Unique Identifier : AIDSLINE MED/92099214; Camilleri AE; Murray S; Squair JL; Imrie CW; Department of Surgery, Glasgow Royal Infirmary, UK.; A prospective study was carried out of all general surgical operations in one theatre of a teaching hospital over a 6-week period to identify the predisposing factors involved in the occurrence of sharps accidents and their relative importance. Although various predisposing factors have been intimated, the relative im
Application of scanning electron microscopy (SEM) and microbead techniques to study the localization of p24 and p18 antigens of HIV-1 on the surface of HIV-1-infected H9-lymphocytes.: J Microsc. 1991 Oct;164 ( Pt 1):53-60. Unique Identifier : AIDSLINE MED/92099302; Dennin RH; Beyer A; Institut fur Medizinische Mikrobiologie, Medizinische; Universitat zu Lubeck, Germany.; Immunofluorescence staining techniques at present, when applied to follow the expression of HIV-1-specific antigens on infected cells, only give the information that the antigens detected are localized in the outer region of the membrane of the infected cell. We therefore set up a procedure using magnetic polystyrol p
Gastrointestinal parasitic infection in healthy Jamaican carriers of HTLV-I.: J Trop Med Hyg. 1991 Dec;94(6):411-5. Unique Identifier : AIDSLINE MED/92099335; Robinson RD; Murphy EL; Wilks RJ; Neva FA; Terry SI; Hanchard B; Figueroa JP; Blattner WA; Department of Zoology, University of the West, Indies, Kingston,; Jamaica.; A subsample (1.6%; n = 13,260) of a healthy Jamaican population of food-handlers, studied by Murphy et al. (1991), who were serologically positive (n = 99) or negative (n = 113) for HTLV-I was investigated for intestinal parasitic infection using coprological methods. Helminth infection included Ascaris lumbricoides (
[Medical application of liposomes]: Rinsho Byori. 1991 Sep;Suppl 91:238-48. Unique Identifier : AIDSLINE MED/92099441; Yasuda T
A case of hives and hip pain following steroid injection.: J Tenn Med Assoc. 1991 Oct;84(10):494-5. Unique Identifier : AIDSLINE MED/92099596; McCroskey DJ; Brown NJ; Morgan HJ; Vanderbilt University Hospital, Nashville.
[Vaccination in immunodepressed patients (editorial)]: Med Clin (Barc). 1991 Oct 19;97(13):497-9. Unique Identifier : AIDSLINE MED/92099680; Calico I
[Cannulas and gloves reduce the risk of blood contamination]: Lakartidningen. 1991 Dec 4;88(49):4237. Unique Identifier : AIDSLINE MED/92099706; van der Linden J; Anestesikliniken, Akademiska sjukhuset, Uppsala.
[Fluconazole in therapy of candidiasis of the oropharyngeal space in patients with HIV infection. Results of an open multicenter study of assessing the effectiveness and tolerance of fluconazole]: Med Klin. 1991 Oct 15;86(10):508-11. Unique Identifier : AIDSLINE MED/92099971; Tschechne B; Brunkhorst U; Ruhnke M; Trautmann M; Dempe S; Deicher H; Abteilung Immunologie und Transfusionsmedizin, Zentrum Innere; Medizin, Medizinische Hochschule, Hannover.; 50 HIV-positive patients (CDC stage III to VI) with oral candidiasis proven by culture and typical clinical findings were treated with fluconazole (50 to 100 mg/day) over a period of eight to 22 days. After completion of treatment, clinical signs of oral candidiasis had disappeared in 45/50 patients. In 10/50 patients
[Pentamidine protecting from the complications of AIDS (news)]: Minerva Pediatr. 1991 Oct;43(10):XII-XIII. Unique Identifier : AIDSLINE MED/92099981; Oliaro A
[Pentamidine against the complications of AIDS (news)]: Minerva Stomatol. 1991 Sep;40(9):XV-XVI. Unique Identifier : AIDSLINE MED/92100017; Oliaro A
[Mycobacterium avium disease in AIDS patients; diagnosis and therapy]: Ned Tijdschr Geneeskd. 1991 Dec 28;135(52):2485-9. Unique Identifier : AIDSLINE MED/92100219; Weits J; Sprenger HG; Ilic P; van Klingeren B; Elema JD; Steensma JT; Interne Kliniek, Academisch Ziekenhuis, Groningen.; In eight (25%) of 32 consecutive AIDS patients between 1986 and 1989, Mycobacterium avium infection was diagnosed: in seven disseminated, in one as a local lymph node process. Six patients were treated as consistently as possible with a combination of ethambutol, rifabutine, clofazimine and protionamide (or cycloserin
False positive auto-antibodies in HIV infection [letter]: Nephron. 1991;59(3):515-6. Unique Identifier : AIDSLINE MED/92100273; Davenport A; Grant PJ
Knowledge of HIV [news]: N J Med. 1991 Nov;88(11):776. Unique Identifier : AIDSLINE MED/92100392
AIDS [news]: N Z Med J. 1991 Dec 11;104(925):524. Unique Identifier : AIDSLINE MED/92100440
AMA sets policy on infectious disease and health-care workers [news]: Ohio Med. 1991 Nov;87(11):532. Unique Identifier : AIDSLINE MED/92100464
AIDS and cancer pain treated with slow release morphine.: Postgrad Med J. 1991;67 Suppl 2:S92-4. Unique Identifier : AIDSLINE MED/92100665; Dixon P; Higginson I; ACET (AIDS Care Education and Training), London, UK.; The use of slow release morphine was compared between those with cancer and those with advanced HIV disease in two retrospective studies covering a total of 512 patients at home. Pain was found to be less severe in HIV/AIDS but still requiring opioid use in over a third of patients of which 14% needed subcutaneous dia
Immunohistochemical studies of human immunodeficiency virus-1 in liver tissues of patients with AIDS.: Mod Pathol. 1991 Sep;4(5):578-81. Unique Identifier : AIDSLINE MED/92100729; Hoda SA; White JE; Gerber MA; Department of Pathology, Tulane University School of Medicine,; New Orleans, Louisiana.; A wide spectrum of hepatic lesions has been reported in AIDS, but it is not known whether the changes are related to the presence of human immunodeficiency virus type 1 (HIV-1). Therefore, we examined liver sections from 15 consecutively autopsied patients with AIDS for the presence of HIV-1 antigens p24 (core) and gp
Exploring the doctor-patient relationship reduces staff stress and enhances empathy when caring for AIDS patients.: Psychother Psychosom. 1991;56(3):167-73. Unique Identifier : AIDSLINE MED/92100846; Battegay M; Weber R; Willi J; Eich D; Siegenthaler W; Luthy R; Department of Medicine, University Hospital, Zurich,; Switzerland.; At our AIDS outpatient clinic we presently care for more than 1,200 HIV-infected patients. All physicians in this unit have participated for 1 year in a case work group supervised by a liaison psychiatrist. The doctor-patient relationship, the assessment in the case work group and the ensuing influence on perception a
[Telephone duty AIDS Information at the Vaudois University Hospital Center: who calls and why?]: Schweiz Med Wochenschr. 1991 Dec 14;121(50):1900-2. Unique Identifier : AIDSLINE MED/92101089; Chave JP; Juvet A; Erismann L; Francioli P; Departement de medecine interne, CHUV, Lausanne.; From January 1989 to December 1990, 7653 phone calls were answered by the AIDS Hot Line of the Centre Hospitalier Universitaire Vaudois. Most of the calls were from the general public (82%), 12% from health care workers and 6% from HIV-infected subjects. The main reasons for calling were information regarding the HIV
[Organization of a bone bank]: Unfallchirurg. 1991 Dec;94(12):619-23. Unique Identifier : AIDSLINE MED/92101104; Stutzle H; Kessler S; Mandelkow H; Schweiberer L; Chirurgische Klinik und Poliklinik,; Ludwig-Maximilians-Universitat Munchen.; The transmission of infectious diseases by allografts from bone banks has led to considerable restrictions on bone transplantations. HIV and hepatitis are considered to be the most dangerous diseases transmitted in this way. To prevent the transmission of any infections, extensive precautions have to be applied when a
Acquired pure amegakaryocytic thrombocytopenic purpura.: Semin Hematol. 1991 Oct;28(4):303-12. Unique Identifier : AIDSLINE MED/92101111; Hoffman R; Department of Medicine, Indiana University School of Medicine,; Indianapolis.
HIV-I testing not covered [letter] [see comments]: Tex Med. 1991 Nov;87(11):6. Unique Identifier : AIDSLINE MED/92101213; Pohl DR
Nurses' risk taking regarding HIV transmission in the workplace.: West J Nurs Res. 1991 Dec;13(6):732-45. Unique Identifier : AIDSLINE MED/92101551; McNabb K; Keller ML; School of Nursing, University of Wisconsin-Madison.
Final report of the Keystone AIDS vaccine liability project. The Keystone Center.: Vaccine. 1991 Oct;9(10):703-9. Unique Identifier : AIDSLINE MED/92101591
HIV vaccines.: Vaccine. 1991 Nov;9(11):777-91. Unique Identifier : AIDSLINE MED/92101603
The quest for vaccines against AIDS: progress and challenges. An overview.: Vaccine. 1991 Nov;9(11):779-81. Unique Identifier : AIDSLINE MED/92101604; Schild GC; Stott EJ
The challenge of HIV vaccines.: Vaccine. 1991 Nov;9(11):781-3. Unique Identifier : AIDSLINE MED/92101605; Girad M; Institut Pasteur, Paris, France.; Immunization of an animal or human being against an infectious agent provides levels of protection that are relative only. Protection can be overcome by high challenge doses. Even with a low challenge dose, protection can vary from absolute to relative. The invading pathogen may be neutralized and eliminated from the
Are we detouring from a direct route to development of HIV vaccines?: Vaccine. 1991 Nov;9(11):783-7. Unique Identifier : AIDSLINE MED/92101606; Fultz PN; Department of Microbiology, University of Alabama, Birmingham; 35294.; Experiments in animal model systems have demonstrated that it is possible for vaccination to elicit immune responses that can prevent or significantly delay lentiviral infection and perhaps disease. To facilitate the development of effective HIV vaccines, current research and development efforts must utilize the appro
SIV vaccines: current status. The role of the SIV-macaque model in AIDS research.: Vaccine. 1991 Nov;9(11):787-91. Unique Identifier : AIDSLINE MED/92101607; Gardner M; Department of Pathology, School of Medicine, University of; California, Davis 95616.; SIV vaccines made of inactivated whole virus, modified live virus and native and recombinant envelope antigens have protected macaques against experimental infection with low doses of cell-free SIV given systemically. The few vaccinated monkeys that do become infected have tended to live longer than the infected contr
Prospects for AIDS vaccines: the need for clinical trials in human populations.: Vaccine. 1991 Nov;9(11):791. Unique Identifier : AIDSLINE MED/92101608; Salk J
[Effect of perioperative allogenic blood transfusion on prognosis of colorectal cancer]: Zentralbl Chir. 1991;116(19):1125-38. Unique Identifier : AIDSLINE MED/92101627; Zimmermann T; Dobroschke J; Borowek U; Padberg W; Klinik fur Allgemeinchirurgie, Justus-Liebig-Universitat; Giessen.; In 1973 the observation was published that in patients who had received non specific blood transfusions before kidney transplantation graft survival was improved. An immunosuppressive effect of blood transfusion was suggested. Indeed, modulation on the cellular and humoral immunologic system has been demonstrated duri
[AIDS in children: selected topics for pediatric practice]: Arztl Jugendkd. 1991;82(2):119-22. Unique Identifier : AIDSLINE MED/92101847; Ratzmann GW; Klinik fur Kindermedizin, Ernst-Moritz-Arndt-Universitat,; Greifswald, Bundesrepublik Deutschland.
Interleukin-2 enhances production in 24 hours of infectious human immunodeficiency virus type 1 in vitro by naturally infected mononuclear cells from seropositive donors.: Arch Virol. 1991;121(1-4):227-32. Unique Identifier : AIDSLINE MED/92102350; Todd B; Pope JH; Georghiou P; Sir Albert Sakzewski Virus Research Laboratory, Royal Children's; Hospital, Brisbane, Queensland, Australia.; When peripheral blood mononuclear cells from HIV-1 seropositive patients were treated with rIL-2 in vitro a rapid increase of 2-12 fold in production of extracellular infectious HIV-1 occurred, in 6 of 9 experiments. Overall, the increase in the 9 experiments was significant (p less than 0.01) and provides more direct
Adult T-cell leukaemia lymphoma in an aborigine.: Aust N Z J Med. 1991 Oct;21(5):739-41. Unique Identifier : AIDSLINE MED/92102408; Kirkland MA; Frasca J; Bastian I; Department of Haematology, Flinders Medical Centre, Adelaide, SA.; A 44-year-old Aborigine with Adult T-cell Leukaemia/Lymphoma (ATLL) due to HTLV-I is reported. He presented with transverse myelitis of subacute onset, and subsequently developed frank T-cell leukaemia complicated by splenomegaly and hypercalcaemia. Cell surface marker studies showed a phenotype of CD3+ CD4+ CD8- CD25
Invasive aspergillosis in AIDS.: Aust N Z J Med. 1991 Oct;21(5):747-9. Unique Identifier : AIDSLINE MED/92102411; Fairley CK; Kent SJ; Street A; Mijch A; Hoy J; Department of Infectious Diseases, Fairfield Hospital, Melbourne,; Vic., Australia.; Invasive aspergillosis (IA) is a rare infection in patients with the Acquired Immune Deficiency Syndrome (AIDS). We report the first Australian cases of histologically and microbiologically proven IA diagnosed antemortem in AIDS patients. We also describe the first case of laryngeal involvement and the unusual case of
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):859-60. Unique Identifier : AIDSLINE MED/92102760; Gama Sosa MA; DeGasperi R; Kim YS; Fazely F; Sharma P; Ruprecht RM
Antigenic domains of the HIV-1 vif protein as recognized by human sera and murine monoclonal antibodies.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):861-7. Unique Identifier : AIDSLINE MED/92102761; Wieland U; Kratschmann H; Kehm R; Kuhn JE; Naher H; Kramer MD; Braun RW; Institute of Medical Virology, University of Heidelberg, Federal; Republic of Germany.; To analyze the vif antibody response in individuals infected with the human immunodeficiency virus type 1 (HIV-1) and to determine antigenic epitopes on the vif protein, 104 HIV-1+ sera were screened for reactivity with a recombinant vif protein; 30 (28.8%) of these sera recognized the recombinant vif protein in immun
In vivo sequence variation of the human immunodeficiency virus type 1 env gene: evidence for recombination among variants found in a single individual.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):869-76. Unique Identifier : AIDSLINE MED/92102762; Howell RM; Fitzgibbon JE; Noe M; Ren ZJ; Gocke DJ; Schwartzer TA; Dubin DT; Department of Molecular Genetics and Microbiology, University of; Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical; School, Piscataway 08854.; To assess in vivo sequence heterogeneity of the human immunodeficiency virus type 1 (HIV-1) env gene, we used the polymerase chain reaction to amplify proviral sequences present in peripheral blood mononuclear cell DNA of a patient with acquired immunodeficiency syndrome (AIDS). The amplified env gene fragment (575 bp
Human chromosome-dependent and -independent pathways for HIV-2 trans-activation.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):877-82. Unique Identifier : AIDSLINE MED/92102763; Hart CE; Westhafer MA; Galphin JC; Ou CY; Bacheler LT; Petteway SR Jr; Wasmuth JJ; Chen IS; Schochetman G; Centers for Disease Control, Atlanta, GA 30333.; Human immunodeficiency virus (HIV types 1 and 2) replication is controlled by the interaction of viral-encoded regulatory proteins and host cellular proteins with the viral long terminal repeat (LTR). The presence of HIV-1 and HIV-2 trans-activator proteins, tat1 and tat2, respectively, greatly increases viral gene ex
Functional and immunological characterization of SIV envelope glycoprotein produced in genetically engineered mammalian cells.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):889-98. Unique Identifier : AIDSLINE MED/92102765; Planelles V; Haigwood NL; Marthas ML; Mann KA; Scandella C; Lidster WD; Shuster JR; Van Kuyk R; Marx PA; Gardner MB; et al; Department of Medical Pathology, University of California, Davis; 95616.; Retroviral envelope glycoproteins interact with cell receptors and are targets for antiviral immune responses in infected hosts. Macaque simian immunodeficiency virus (SIVmac) is a T-lymphocytopathic lentivirus which causes an AIDS-like disease in rhesus macaques. The envelope gene of SIVmac encodes a precursor glycop
Nucleotide sequence analysis of isolates of human T-lymphotropic virus type 1 of diverse geographical origins.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):923-41. Unique Identifier : AIDSLINE GENBANK/M81694; Ratner L; Philpott T; Trowbridge DB; Department of Medicine, Washington University School of Medicine,; St. Louis, MO 63110.; Nucleotide sequences for long terminal repeat (LTR), gag, the protease gene, and pol of a human T-lymphotropic virus type 1 (HTLV-1) isolate of probable Caribbean origin (HTLV-1CH) and a Zairian isolate (HTLV-1EL) were determined providing complete proviral sequences for these isolates. These sequences were compared w
Differential alteration of the anti-HIV-1 effect of phosphorothioate oligonucleotide S-dC28 by AZT, interferon-alpha, and dextran sulfate.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):943-51. Unique Identifier : AIDSLINE MED/92102769; Chou TC; Zhu QY; Stein CA; Laboratory of Biochemical Pharmacology, Memorial Sloan-Kettering; Cancer Center, New York 10021.; The combination of S-dC28 (a phosphorothioate oligodeoxcytidine 28 mer) with AZT , recombinant interferon alpha-A (IFN-alpha A) or dextran sulfate (DS) against replication of human immunodeficiency virus type 1 (HIV-1) were studied in MT4 cells, using
Proliferative response of mononuclear cells from HIV-infected patients to B-cell mitogens: effects of lymphocyte subset frequency, T-cell defects and prostaglandins.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):953-61. Unique Identifier : AIDSLINE MED/92102770; Edelman AS; Zolla-Pazner S; Department of Pathology, New York University Medical Center; 10016.; Proliferative responses of mononuclear cells from patients seropositive for human immunodeficiency virus to B-cell mitogens are severely depressed compared with those of controls. The role of several immunoregulatory phenomena was analyzed. Experimental results show that addition of exogenous lymphokines to cultures i
Update on AIDS.: Wkly Epidemiol Rec. 1991 Nov 29;66(48):353-7. Unique Identifier : AIDSLINE MED/92102835
AIDS focus. Groups for people with HIV/AIDS.: Nurs Stand. 1991 Dec 11-17;6(12):50-1. Unique Identifier : AIDSLINE MED/92102864; Bor R; Tilling J
AIDS focus. Sexuality, saints and sinners.: Nurs Stand. 1991 Dec 11-17;6(12):52-5. Unique Identifier : AIDSLINE MED/92102865; Sundquist K
AIDS focus. The challenge of the nineties.: Nurs Stand. 1991 Dec 11-17;6(12):56. Unique Identifier : AIDSLINE MED/92102866; Alderman C
Management of fungal infections.: Nurs Stand. 1991 Nov 20-26;6(9):38-40. Unique Identifier : AIDSLINE MED/92102915; White G
Infection of human CD4+ rabbit cells with HIV-1: the possibility of the rabbit as a model for HIV-1 infection.: Int Immunol. 1991 Nov;3(11):1183-7. Unique Identifier : AIDSLINE MED/92103004; Yamamura Y; Kotani M; Chowdhury MI; Yamamoto N; Yamaguchi K; Karasuyama H; Katsura Y; Miyasaka M; Department of Immunology, Tokyo Metropolitan Institute of Medical; Science, Japan.; Although human T cell surface glycoprotein CD4 is the cellular receptor for human immunodeficiency virus 1 (HIV-1), the introduction of the human CD4 gene into murine cells does not render them susceptible to HIV-1 infection. Here we have established rabbit transfectant cell lines expressing human CD4 on the cell surf
Gay men and HIV/AIDS: understanding the double stigma.: J Assoc Nurses AIDS Care. 1991;2(4):28-32. Unique Identifier : AIDSLINE MED/92103195; Grossman AH; Many men with HIV/AIDS are and will continue to be homosexual or bisexual. Effective care requires understanding the impact of the double stigma of being gay and having HIV/AIDS. While providers have traditionally focused on gay men with HIV disease as individuals, this article directs providers attention to the impo
Overcoming methodological barriers to HIV/AIDS nursing research.: J Assoc Nurses AIDS Care. 1991;2(4):33-7. Unique Identifier : AIDSLINE MED/92103196; Gaskins S; Sowell R; Gueldner S; While more than 1,600 articles have been published in the nursing literature about HIV infection, only 54 (3%) have been research articles. The sparsity of nursing research related to HIV has partially resulted from methodological problems inherent in the implementation of research protocols with persons infected with
How long can HIV survive on environmental surfaces?: J Assoc Nurses AIDS Care. 1991;2(4):39. Unique Identifier : AIDSLINE MED/92103197; LaBombardi V
Association of Nurses in AIDS care. Position paper: duty to care.: J Assoc Nurses AIDS Care. 1991;2(4):44. Unique Identifier : AIDSLINE MED/92103198
Ten years: looking back, looking forward [editorial]: J Assoc Nurses AIDS Care. 1991;2(4):6. Unique Identifier : AIDSLINE MED/92103199; Simons JD
Tuberculosis: the other epidemic.: J Assoc Nurses AIDS Care. 1991;2(4):9-24. Unique Identifier : AIDSLINE MED/92103200; Allen MA; Ownby KK; In 1990, the number of cases of tuberculosis (TB) reported in the United States rose 6%. This is a noticeable change since, in prior years, TB had been declining. The increased incidence of TB is largely related to the HIV epidemic. TB is of particular interest in HIV-related illnesses
German haemophilic patients infected with HIV [news]: BMJ. 1991 Nov 30;303(6814):1352-3. Unique Identifier : AIDSLINE MED/92103347; Karcher H
Prison policies on HIV under review [news]: BMJ. 1991 Nov 30;303(6814):1354. Unique Identifier : AIDSLINE MED/92103348; Groves T
How do patients with HIV perceive their general practitioners?: BMJ. 1991 Nov 30;303(6814):1365-8. Unique Identifier : AIDSLINE MED/92103351; Kochen MM; Hasford JC; Jager H; Zippel S; L'age M; Rosendahl C; Fuessl HS; Eichenlaub D; Ludwig-Maximilians-University, Munich, Germany.; OBJECTIVE--To study the perceptions of patients with HIV of their general practitioners in terms of knowledge, abilities, confidence, and satisfaction. DESIGN--Questionnaire survey of inpatients, outpatients, and members of a self help group. SETTING--Two city hospitals, three outpatient clinics, and one AIDS self hel
Zidovudine after occupational exposure to HIV [letter; comment]: BMJ. 1991 Nov 30;303(6814):1404. Unique Identifier : AIDSLINE MED/92103373; De Wind CM
Seafarers and HIV infection [letter; comment]: BMJ. 1991 Nov 30;303(6814):1405. Unique Identifier : AIDSLINE MED/92103376
Stability of CD4/CD8 ratios in man: new correlation between CD4/CD8 profiles and iron overload in idiopathic haemochromatosis patients.: C R Acad Sci III. 1991;313(11):481-7. Unique Identifier : AIDSLINE MED/92103550; Reimao R; Porto G; de Sousa M; Institut Abel Salazar des Sciences biomedicales, Porto,; Portugal.; The proportions of CD4+, CD8+ cells were determined in peripheral blood samples obtained from 27 patients with idiopathic haemochromatosis and 67 healthy controls. Samples from the patients were obtained at the start of therapy and at intervals during intensive phlebotomy treatment in which 400 ml of blood are removed
Enhanced expansion of the thymic CD8+ cell subset as a potential mechanism for the generation of enhanced antitumor cytotoxicity by thymocytes from low-dose melphalan-treated MOPC-315 tumor bearers.: Cancer Immunol Immunother. 1991;34(2):79-89. Unique Identifier : AIDSLINE MED/92103650; Bartik MM; Baumgartel-Scofield BA; Mokyr MB; Department of Microbiology and Immunology, University of; Illinois, Chicago 60680.; We have previously shown that thymocytes from low-dose melphalan (L-phenylalanine mustard)-treated MOPC-315-tumor-bearing mice (melphalan TuB) are able to generate an enhanced level of anti-MOPC-315 cytotoxicity, as compared to thymocytes from untreated MOPC-315-tumor-bearing mice or thymocytes from untreated or low-d
HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer.: Cell. 1991 Dec 20;67(6):1211-21. Unique Identifier : AIDSLINE MED/92103686; Engelman A; Mizuuchi K; Craigie R; Laboratory of Molecular Biology, National Institute of Diabetes; and Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, Maryland 20892.; Retroviral DNA integration involves a coordinated set of DNA cutting and joining reactions. Linear viral DNA is cleaved at each 3 end to generate the precursor ends for integration. The resulting recessed 3 ends are inserted into target DNA by a subsequent DNA strand transfer reaction. Purified HIV-1 integration pro
[Guidelines for allogeneic bone transplantation]: Chirurg. 1991 Oct;62(10):763-5. Unique Identifier : AIDSLINE MED/92104053; Knaepler H; Ascherl R; von Garrel T; Gotzen L; Klinik fur Unfallchirurgie, Philipps-Universitat Marburg/Lahn.
[Infection screening in pregnancy]: Gynakol Rundsch. 1991;31(3):167-85. Unique Identifier : AIDSLINE MED/92104524; Gyr T; Schneider H; Linder HR; Universitats-Frauenklinik, Bern, Schweiz.; The aim of screening for infectious diseases in pregnancy is to identify subjects who are at risk of a specific infection, which lends itself to effective intervention. The value of routine screening is determined by the validity of the test and the prevalence of the disorder in the population. During pregnancy, serol
Spleen cell dialyzable extracts (SCDE) mediated immunotherapy for patients with myasthenia gravis.: Int J Immunopharmacol. 1991;13(7):825-9. Unique Identifier : AIDSLINE MED/92104746; Yang BZ; Li ZL; Cui ZY; Luo YM; Department of Immunology and Microbiology, Weifang Medical; College, Shandong, People's Republic of China.; We studied 14 cases of myasthenia gravis (MG) with regard to their anti-acetylcholine receptor antibody (AChR-Ab) production, peripheral blood CD4+/CD8+ ratio, and responses of peripheral lymphocytes to PHA and PWM stimulations. We found that the clinical severity was not proportional to AChR-Ab level in serum in term
Differential staphylococcal protein A-induced enhancement of natural killer cell activity of lymphocytes from HIV-seropositive individuals.: Int J Immunopharmacol. 1991;13(7):865-73. Unique Identifier : AIDSLINE MED/92104751; Kasparian S; Stefanescu I; Rivard GE; Menezes J; Laboratory of Immunovirology, University of Montreal, Quebec,; Canada.; A decrease in Natural Killer (NK) cell activity is a common feature of the immune dysfunction found in patients with HIV-induced acquired immune deficiency syndrome (AIDS). We and others have shown earlier that staphylococcal protein A (SpA) preparations enhance NK cell activity against tumor targets. The present stud
Clinical benefits and recovery of delayed-type hypersensitivity in patients with AIDS-related complex treated with IMREG-1 or placebo.: Int J Immunopharmacol. 1991;13(7):999-1004. Unique Identifier : AIDSLINE MED/92104766; Fiala M; Cone LA; Sayre JW; Eisenhower Medical Center, Rancho Mirage, California.; IMREG-1, an immunomodulatory biological therapeutic, was studied in a placebo-controlled, double-blind, six-month trial in 45 anergic patients with AIDS-related complex (ARC) and 4 with Kaposi s sarcoma, which was followed by compassionate IMREG-1 administration to all subjects. The IMREG-1 group had significantly les
Influencers of career choice among allied health students.: J Allied Health. 1991 Summer;20(3):181-9. Unique Identifier : AIDSLINE MED/92104830; Brown-West AP; School of Professional Studies, University of Maryland Eastern; Shore, Princess Anne 21853.; This study focused on the factors that influence students choice of an allied health profession. A survey of 153 students in three allied health programs at the University of Connecticut revealed that the need to help others, prestige, professional autonomy, opportunities for advancement, income potential, and the ef
An evaluation of AIDS education: a quasi-experimental exploration.: J Allied Health. 1991 Summer;20(3):191-202. Unique Identifier : AIDSLINE MED/92104831; Kowaleski L; Zeller R; Willis C; Department of Sociology, Bowling Green State University, OH; 43402.; This study reports on a quasi-experimental study designed to evaluate the relationship between receiving classroom instruction and subsequent AIDS knowledge, behavior, and attitudes. Survey information was gathered from 61 students enrolled in an AIDS course and 68 students enrolled in control courses. Both groups wer
Antifungal and antiviral activities of benanomicins and their analogues.: J Antibiot (Tokyo). 1991 Nov;44(11):1228-36. Unique Identifier : AIDSLINE MED/92104839; Kondo S; Gomi S; Ikeda D; Hamada M; Takeuchi T; Iwai H; Seki J; Hoshino H; Department of Hygiene, Gunma University School of Medicine,; Japan.; In vitro activities of benanomicins and their analogues against human immunodeficiency virus and fungi including Candida, Cryptococcus and Aspergillus, were examined. The free carboxyl group and at least one sugar moiety in the benanomicins were essential for their activities. Benanomicin A was most active and had low
Kinetic studies of human immunodeficiency virus type 1 protease and its active-site hydrogen bond mutant A28S.: J Biol Chem. 1991 Dec 25;266(36):24359-66. Unique Identifier : AIDSLINE GENBANK/M55201; Ido E; Han HP; Kezdy FJ; Tang J; Protein Studies Program, Oklahoma Medical Research Foundation,; Oklahoma City 73104.; Human immunodeficiency virus type 1 (HIV-1) protease optimally catalyzes in the pH range of 4-6 in contrast to nearly all of the other eukaryotic aspartic proteases, which catalyze best in the pH range of 2-4. A possible structural reason for the higher optimal pH of HIV-1 protease is the absence of a hydrogen bond to
Subset markers of CD8(+) cells and their relation to enhanced cytotoxic T-cell activity during human immunodeficiency virus infection.: J Clin Immunol. 1991 Nov;11(6):345-56. Unique Identifier : AIDSLINE MED/92105279; Vanham G; Kestens L; Penne G; Goilav C; Gigase P; Colebunders R; Vandenbruaene M; Goeman J; van der Groen G; Ceuppens JL; Laboratory of Pathology & Immunology, Institute of Tropical; Medicine, Antwerp, Belgium.; Using fresh whole blood or isolated lymphocytes, the activity of in vivo generated cytotoxic T-lymphocytes (CTL) was measured as the OKT3-specific lysis of HL-60 targets, in a cross-sectional study of 53 HIV (+) patients. CTL activity in the entire HIV(+) group was two to three times higher than in HIV(-) controls, wi
Nodular cutaneous B-cell lymphoma of the scalp in the acquired immunodeficiency syndrome.: J Am Acad Dermatol. 1991 Nov;25(5 Pt 2):933-6. Unique Identifier : AIDSLINE MED/92105515; Burns MK; Kennard CD; Dubin HV; Department of Dermatology, University of Michigan Medical Center,; Ann Arbor 41809-0314.; Aggressive B-cell non-Hodgkin s lymphoma frequently complicates human immunodeficiency virus type 1 infection. Although extranodal disease is an important feature of this condition, the incidence of cutaneous involvement has not been determined. A review of 754 published cases of B
HIV-1 gp41 antigen demonstration in esophageal ulcers with acquired immunodeficiency syndrome.: J Clin Gastroenterol. 1991 Dec;13(6):644-8. Unique Identifier : AIDSLINE MED/92105666; Jalfon IM; Sitton JE; Hammer RA; Agrawal NM; Ertan A; Mahatma M; Department of Medicine, Tulane University School of Medicine, New; Orleans, Louisiana 70112.; Esophageal ulcers associated with acquired immunodeficiency syndrome (AIDS) may be chronic, debilitating, and resistant to antifungal or antiviral therapy. The therapeutic management of these lesions remains controversial due to the difficulty in identifying pathogenic agent(s). We review previously published cases an
[Clinical study on ivermectin against Strongyloides stercoralis]: Kansenshogaku Zasshi. 1991 Sep;65(9):1085-90. Unique Identifier : AIDSLINE MED/92105801; Shikiya K; Uehara T; Uechi H; Ohshiro J; Arakaki T; Oyakawa T; Sakugawa H; Kinjo F; Saito A; Asato R; First Department of Internal Medicine, Faculty of Medicine,; University of the Ryukyus.; We previously reported the efficacy of ivermectin (IVM) for the treatment of 23 strongyloidiasis patients. We now reported the efficacy and safety of IVM therapy on 54 patients. Fifty-four patients, 28 males and 26 females, received a single oral dose of IVM one hour before breakfast and this treatment was repeated 2
[Detection of immune complex by C1q solid phase enzyme immunoassay]: Rinsho Byori. 1991 Oct;39(10):1098-104. Unique Identifier : AIDSLINE MED/92106507; Sakaeda H; Igata H; Mibuchi Y; Yonemasu K; Department of Research & Development, Japan Medical Laboratories,; Onojo.; We have developed a new and improved method for detecting immune complexes (IC) by C1q solid-phase enzyme immunoassay (CSP-EIA). The sensitivity of this method was between 0.62 micrograms/ml and 1.25 micrograms/ml, and values in normal individuals were 1.8 micrograms/ml and less. The positive rate of IC of sera in whi
[Lymphocytic subsets of tumor tissue, non tumorous kidney, and the peripheral blood in primary renal cell carcinoma]: Nippon Hinyokika Gakkai Zasshi. 1991 Nov;82(11):1781-9. Unique Identifier : AIDSLINE MED/92106620; Nagase Y; Moriyama N; Hosaka Y; Higashihara E; Murahashi I; Aso Y; Department of Urology, Branch Hospital, Faculty of Medicine,; University of Tokyo.; Lymphocyte subsets were examined in renal cell carcinoma (TILs), adjacent non-tumor renal tissue and peripheral blood (PBLs) by flow cytometry and histochemistry in eighteen patients with renal cell carcinoma. CD5-positive cells were predominant in the TILs in 14 patients. In the renal cell carcinoma tissue, CD8-posit
[The AIDS nursing concept of the German Federation of Nurses]: Krankenpflege (Frankf). 1991 Nov;45(11):606-8. Unique Identifier : AIDSLINE MED/92106760; Sowinski C
[Safety for the care givers]: Krankenpflege (Frankf). 1991 Nov;45(11):608-12. Unique Identifier : AIDSLINE MED/92106761; Schumacher B
[Alternative nursing possibilities for patients with AIDS]: Krankenpflege (Frankf). 1991 Nov;45(11):612-8. Unique Identifier : AIDSLINE MED/92106762; Recht C; Mittmann S
Individual responsibility.: J S C Med Assoc. 1991 Dec;87(12):563. Unique Identifier : AIDSLINE MED/92106795; Hawk JC 3d
Computer-assisted drug design. Part I. Conditions in the 1980s.: Med Res Rev. 1991 Nov;11(6):641-62. Unique Identifier : AIDSLINE MED/92106860; Snyder JP; Drug Design, Searle Research & Development, Skokie, Illinois; 60077.
The nurse executive and AIDS.: Mass Nurse. 1991 Dec;61(9):11-2. Unique Identifier : AIDSLINE MED/92107031; Edwards PA
Research commentary: testimony--Special Commission on Nursing Practice.: Mass Nurse. 1991 Dec;61(9):6. Unique Identifier : AIDSLINE MED/92107034; Skydell B
[The importance of the enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of tuberculosis]: Mikrobiyol Bul. 1991 Jul;25(3):294-8. Unique Identifier : AIDSLINE MED/92107116; Sacilik SC; Ankara Universitesi, Fen Fakultesi, Biyoloji Bolumu.; The remainders of tuberculosis infection are still existing as a problem, as important and threatening as AIDS (acquired immune deficiency syndrome), especially in underdeveloped countries. The diagnosis of tuberculosis infection frequently creates problems which is related to clinical, radiological and bacteriologica
Understanding OSHA's bloodborne pathogen standard [editorial]: Mo Med. 1991 Dec;88(12):795-6. Unique Identifier : AIDSLINE MED/92107133; Petroshak PJ
The use of alternative therapies by HIV-positive patients attending the St. Louis AIDS Clinical Trials Unit.: Mo Med. 1991 Dec;88(12):807-10. Unique Identifier : AIDSLINE MED/92107136; Rowlands C; Powderly WG; AIDS Clinical Trials Unit, Washington University School of; Medicine, St. Louis 63110.
Cost-effectiveness of drug abuse treatment for primary prevention of acquired immunodeficiency syndrome: epidemiologic considerations.: NIDA Res Monogr. 1991;113:114-28. Unique Identifier : AIDSLINE MED/92107272; Lampinen TM; AIDS Outreach Intervention Project, University of Illinois,; Chicago School of Public Health (M/C 922) 60612.; The prevention of AIDS has justified recent increases in drug abuse treatment expenditures. Three of the epidemiologic considerations involved in assessing the cost-effectiveness of drug treatment for primary prevention of AIDS among IV drug users were discussed. First, the considerable geographic variation in the pre
Fighting AIDS [letter]: N J Med. 1991 Dec;88(12):883. Unique Identifier : AIDSLINE MED/92107408; Samson ID
Purified recombinant CD4 inhibits HIV-1 infection of peripheral blood macrophages.: Pathol Biol (Paris). 1991 Oct;39(8):754-8. Unique Identifier : AIDSLINE MED/92107565; Molina JM; Ferriani R; Amirault C; Groopman JE; Division of Hematology/Oncology, New England Deaconess Hospital,; Boston, MA.; Purified recombinant soluble CD4 (rCD 4) is a new antiviral agent which has been shown to block HIV infection of lymphocytic and monocytic cell lines as well as peripheral blood mononuclear cells. The authors investigated here the ability of rCD4 to inhibit HIV-1 infection of peripheral blood macrophages. In this syst
Mandatory HIV testing of health care workers.: N J Nurse. 1991 Nov-Dec;21(6):12. Unique Identifier : AIDSLINE MED/92107633; Haq MB
Elected to counsel.: Nurs Times. 1991 Nov 13-19;87(46):22. Unique Identifier : AIDSLINE MED/92107747; Faugier J
Psychiatric help needed for people with HIV [news]: Nurs Times. 1991 Nov 13-19;87(46):8. Unique Identifier : AIDSLINE MED/92107761; McMillan I
Evolution of human immunodeficiency virus type 1 nucleotide sequence diversity among close contacts.: Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11236-40. Unique Identifier : AIDSLINE GENBANK/M77230; Burger H; Weiser B; Flaherty K; Gulla J; Nguyen PN; Gibbs RA; Department of Medicine, State University of New York, Stony Brook; 11794.; The degree of change in the nucleotide sequence of human immunodeficiency virus type 1 (HIV-1) that occurs when it is transmitted sexually from one individual to another or vertically from mother to child is unknown. Previous studies have shown that most cultured HIV-1 isolates from the same individuals differed in th
CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.: Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11320-4. Unique Identifier : AIDSLINE MED/92107941; Pollard SR; Meier W; Chow P; Rosa JJ; Wiley DC; Biogen Incorporated, Cambridge, MA 02142.; The gp120 envelope glycoprotein of human immunodeficiency virus type 1 binds the cell surface protein CD4 with high affinity. Here we report the use of proteolysis to define regions of gp120 involved in CD4 binding. Cleavage of gp120 with Staphylococcus aureus V8 protease at residue 269 or with trypsin at residue 432
Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer.: Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11445-9. Unique Identifier : AIDSLINE MED/92107967; Zhao LJ; Giam CZ; Department of Medicine, Case Western Reserve University School of; Medicine, Cleveland, OH 44106.; The human T-cell lymphotrophic virus type I (HTLV-I) Tax protein activates transcription from three 21-base-pair (bp) repeat sequences in the viral enhancer. Using gel electrophoretic mobility-shift assays, we now show that Tax interacts directly with the nuclear proteins, Tax activation factors (TAFs), that bind the
Where there's life ... Intensive care for patients with AIDS and HIV.: Prof Nurse. 1991 Dec;7(3):175-7. Unique Identifier : AIDSLINE MED/92108095; Taylor J; The most common cause of Aids-related death is respiratory failure. Although the mortality rates are high, drug therapy can lead to successful outcomes. By keeping up-to-date with current developments, nurses working in ICUs can help adapt practice to suit individual needs and requirements.
The potential use of catalytic RNAs in therapy of HIV infection and other diseases.: Pharmacol Ther. 1991;50(2):245-54. Unique Identifier : AIDSLINE MED/92108161; Rossi JJ; Cantin EM; Sarver N; Chang PF; Department of Molecular Genetics, Beckman Research Institute of; the City of Hope, Duarte, CA 91010.; This article describes the applications (both real and potential) of a new antiviral strategy, based on the use of antisense, catalytic RNAs (ribozymes) as therapeutic agents. An understanding of both antisense inhibition of gene expression and RNA autocleavage reactions are essential to the use of this technology. In
The Basic HIV Disease Knowledge Questionnaire: a Rasch-scaled instrument to measure essential HIV knowledge.: Psychol Rep. 1991 Oct;69(2):543-9. Unique Identifier : AIDSLINE MED/92108195; McCown W; Johnson J; Hahnemann University, Philadelphia, PA 19012.; The need for improvement in HIV disease-related psychometric questionnaires is noted. In response to this need a Rasch-scaled measure to ascertain basic HIV disease knowledge was developed and calibrated on 1092 subjects. Four studies conducted with the measure suggest adequate test-retest reliability. Three validity
Pharmacokinetics of peptide T in patients with acquired immunodeficiency syndrome (AIDS).: Prog Neuropsychopharmacol Biol Psychiatry. 1991;15(6):791-801. Unique Identifier : AIDSLINE MED/92108228; Ruff MR; Smith C; Kingan T; Jaffe H; Heseltine P; Gill MA; Mayer K; Pert CB; Bridge TP; Integra Institute, Potomac, MD.; 1. The pharmacokinetics of Dala1-peptide T-NH2 (peptide T) was determined during phase I clinical trials in patients with acquired immunodeficiency disease (AIDS) and AIDS related complex (ARC). Drug levels were determined by specific RIA, and in some cases with HPLC analysis, after intravenous (i.v.) or intranasal (i
[Respiratory cryptosporidiosis: apropos of a new case (letter)]: Rev Clin Esp. 1991 Oct;189(6):300-1. Unique Identifier : AIDSLINE MED/92108282; Martin Sanchez AM; Rodriguez Hernandez J; Fuertes Martin A; Canut Blasco A
[Cervical actinomycosis in a carrier of human immunodeficiency virus (letter)]: Rev Clin Esp. 1991 Oct;189(6):301-2. Unique Identifier : AIDSLINE MED/92108284; Molina M; Ortega G; de Paco M; Montoya JJ
[Hepatic epithelioid angiomatosis in the absence of HIV infection (letter)]: Rev Clin Esp. 1991 Oct;189(6):302-3. Unique Identifier : AIDSLINE MED/92108285; Nunez Sanchez JC; Iglesias Estevan F; Lopez Almenar A
Purine nucleotide content of lymphocytes from healthy subjects and asymptomatic HIV-1 seropositive patients.: Recenti Prog Med. 1991 Nov;82(11):581-4. Unique Identifier : AIDSLINE MED/92108306; Tabucchi A; Carlucci F; Marinello E; Re MC; Bisozzi L; Cacopardo F; Pagani R; Istituto di Biochimica e di Enzimologia, Universita, Siena.; The purine nucleotide content of lymphocytes of normal subjects and asymptomatic HIV-1 seropositive patients was analyzed by HPLC. An increase in IMP and a decrease in ADP, GDP, ATP and GPT were observed in the HIV-infected patients with respect to healthy subjects. The changes may depend on different factors and indi
Applying the chronic illness Trajectory Model to HIV/AIDS.: Sch Inq Nurs Pract. 1991 Fall;5(3):197-204. Unique Identifier : AIDSLINE MED/92108320; Nokes KM; The Corbin and Strauss chronic illness trajectory model is particularly helpful in explaining the different phases of HIV (Human Immunodeficiency Virus) disease, since this infectious process is characterized by both phases and subphases. The model is not particularly helpful in identifying when the illness trajectory
[AIDS--a dangerous pandemic (editorial)]: Schweiz Monatsschr Zahnmed. 1991;101(12):1519, 1521. Unique Identifier : AIDSLINE MED/92108396; Venner K
[The Turbocid. An apparatus for the cleaning, disinfection and lubrication of handpieces, anglepieces and turbines]: Schweiz Monatsschr Zahnmed. 1991;101(12):1570-85. Unique Identifier : AIDSLINE MED/92108401; Guggenheim B; Gander M; Roth U; Abteilung fur Orale Mikrobiologie und Allgemeine Immunologie,; Universitat Zurich.
[The prevention of AIDS: possibilities and limits]: Schweiz Monatsschr Zahnmed. 1991;101(12):1613-4, 1621-2. Unique Identifier : AIDSLINE MED/92108403; Venner K
New AIDS drug poised to move into development [news]: Science. 1991 Dec 20;254(5039):1715. Unique Identifier : AIDSLINE MED/92108407
HIV risk higher for first-born twins [news]: Science. 1991 Dec 20;254(5039):1729. Unique Identifier : AIDSLINE MED/92108413; Palca J
Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist.: Science. 1991 Dec 20;254(5039):1799-802. Unique Identifier : AIDSLINE MED/92108427; Hsu MC; Schutt AD; Holly M; Slice LW; Sherman MI; Richman DD; Potash MJ; Volsky DJ; Department of Virology, Hoffmann-La Roche, Nutley, NJ 07110.; The human immunodeficiency virus-1 (HIV-1) trans-activator Tat is an attractive target for the development of antiviral drugs because inhibition of Tat would arrest the virus at an early stage. The drug Ro 5-3335 [7-chloro-5-(2-pyrryl)-3H-1,4-benzodiazepine-2(H)-one], inhibited gene expression by HIV-1 at the level of
House of Delegates reaffirms voluntary, confidential testing for HIV.: S D Nurse. 1991 Nov;33(4):9, 11. Unique Identifier : AIDSLINE MED/92108433
Can anti-HBc testing decrease the residual risk of transfusion-related HIV transmission? [letter]: Vox Sang. 1991;61(2):144-5. Unique Identifier : AIDSLINE MED/92108732; Fiedler H
[Nicotine--drug addiction--AIDS. Drug use habits of Vienna addicts]: Wien Klin Wochenschr. 1991;103(20):617-20. Unique Identifier : AIDSLINE MED/92108742; Loimer N; Vedovelli H; Presslich O; Werner E; Hollerer E; Pfersmann V; Schmid-Siegel B; Psychiatrische Universitatsklinik, Wien.; In Austria it is illegal to sell tobacco to young adolescents. A diverse sample of 358 narcotic addicts was investigated at the Psychiatric University Clinic of Vienna. Data were obtained from on site confidential interviews and a HIV-test was conducted. The individual drug use hi
Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS.: DICP. 1991 Nov;25(11):1171-4. Unique Identifier : AIDSLINE MED/92108764; Briceland LL; Bailie GR; Albany College of Pharmacy, NY 12208.; The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities. There were 37 patients, mean age 35.6 +/- 7.7 years and mean initial creatinine clearance (Clcr) 96 mL/min (1.6 mL/s). The mea
Highlights of the 29th annual meeting of the American Society of Neuroradiology, Washington, DC, June 9-14, 1991.: AJNR Am J Neuroradiol. 1991 Nov-Dec;12(6):1241-9. Unique Identifier : AIDSLINE MED/92109115; Bryan RN; Caille JM; Chakeres DW; DeBrun G; Dillon WP; Fram EK; Lo WW; Masaryk TJ; Mawad ME; Moody DM; et al; Johns Hopkins Hospital, Baltimore, MD 21205.
DdI for AIDS patients intolerant to AZT [news]: Am Pharm. 1991 Dec;NS31(12):10. Unique Identifier : AIDSLINE MED/92109174
Antibiotic more effective for AIDS-related pneumonia [news]: Am Pharm. 1991 Dec;NS31(12):18. Unique Identifier : AIDSLINE MED/92109175
DdI approval offers second chance [letter]: Am Pharm. 1991 Dec;NS31(12):6. Unique Identifier : AIDSLINE MED/92109185; Albert SG
Low prevalence of human immunodeficiency virus-1 (HIV-1), HIV-2, and human T cell lymphotropic virus-1 infection in Somalia.: Am J Trop Med Hyg. 1991 Dec;45(6):653-9. Unique Identifier : AIDSLINE MED/92109270; Scott DA; Corwin AL; Constantine NT; Omar MA; Guled A; Yusef M; Roberts CR; Watts DM; US Naval Medical Research Unit No. 3, Cairo, Egypt.; A seroepidemiologic survey was conducted to determine the prevalence of human immunodeficiency virus type 1 (HIV-1), HIV-2, human T cell lymphotropic virus type I (HTLV-I), and Treponema pallidum infection among southern Somalis. Sera were collected from 1,269 study subjects in the urban area of the capital city, Moga
Acute fatal Trypanosoma cruzi meningoencephalitis in a human immunodeficiency virus-positive hemophiliac patient.: Am J Trop Med Hyg. 1991 Dec;45(6):723-7. Unique Identifier : AIDSLINE MED/92109280; Ferreira MS; Nishioka S de A; Rocha A; Silva AM; Ferreira RG; Olivier W; Tostes Junior S; Centro de Ciencias Biomedicas, Universidade Federal de; Uberlandia, Brazil.; A 37-year-old hemophiliac patient with known, asymptomatic human immunodeficiency virus infection and chronic Chagas disease was admitted to the hospital complaining of fever and headache. A computed tomographic scan revealed multiple ring-enhancing lesions in both cerebral hemispheres. No antibodies to Trypanosoma c
A survey of nurses' knowledge, opinions, and reported uses of the Body Substance Isolation system.: Am J Infect Control. 1991 Dec;19(6):268-76. Unique Identifier : AIDSLINE MED/92109341; Troya SH; Jackson MM; Lovrich-Kerr M; McPherson DC; Epidemiology Unit, University of California San Diego Medical; Center 92103-1990.; The Body Substance Isolation (BSI) system was implemented at the University of California San Diego Medical Center in May 1987. About 2 years later, an evaluation was done of the long-term effects of BSI education and training on the knowledge, attitudes, and reported behaviors of nursing personnel. In June 1989, a qu
The APIC statement on purposes for and elements of patient notification programs related to the health care worker infected with human immunodeficiency virus or the hepatitis B e antigen. The Association for Practitioners in Infection Control, Inc. Committee on Bloodborne Pathogens.: Am J Infect Control. 1991 Dec;19(6):30A-33A. Unique Identifier : AIDSLINE MED/92109345; Williams CO; Jackson MM; Russell B; Counts GW; Valenti WM
[Familial characteristics of children born to HIV-seropositive women]: Arch Fr Pediatr. 1991 Nov;48(9):607-9. Unique Identifier : AIDSLINE MED/92109505; Veber F; Blanche S; Rosset D; Chenuet P; Debre M; Terris J; Griscelli C; Unite d'Immunologie et Hematologie, Hopital; Necker-Enfants-Malades, Paris.; The family situation of 122 children followed at the Necker hospital is analysed in this study: 40% of these children live with both parents, while 22% live with one parent, 10% with their maternal grand mother and 28% are under the care of the Aide Sociale a l Enfance (Social Services for Children). At this time, les
Expression of human T-cell leukemia virus type I protease in Escherichia coli.: Biochem Biophys Res Commun. 1991 Dec 31;181(3):1281-7. Unique Identifier : AIDSLINE MED/92109739; Hayakawa T; Misumi Y; Kobayashi M; Ohi Y; Fujisawa Y; Kakinuma A; Hatanaka M; Biotechnology Research Laboratories, Takeda Chemical Industries,; Ltd., Osaka, Japan.; Human T-cell leukemia virus type I (HTLV-I) genome is believed to encode its own protease, although the protease has not yet been detected. To identify the HTLV-I protease, an in-frame gag (3 portion)-prt region was expressed in Escherichia coli. The 14-kDa product was detected using antisera against a synthetic pept
HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502.: Biochem Biophys Res Commun. 1991 Dec 31;181(3):1456-61. Unique Identifier : AIDSLINE MED/92109765; Lingham RB; Arison BH; Colwell LF; Hsu A; Dezeny G; Thompson WJ; Garrity GM; Gagliardi MM; Hartner FW; Darke PL; et al; Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey; 07065.; L-689,502 is a potent inhibitor of HIV-1 protease activity in vitro. Microbial biotransformations of L-689,502 by cultures belonging to the genus Streptomyces sp. were performed. Extracts of culture broths were examined for the production of metabolites of L-689,502 that could inhibit HIV-1 protease activity. One cult
Pediatric AIDS: comparative cranial MRI and CT scans.: Pediatr Neurol. 1991 Sep-Oct;7(5):357-62. Unique Identifier : AIDSLINE MED/92109822; Chamberlain MC; Nichols SL; Chase CH; Department of Neurosciences, University of California, San Diego; 92103.; Fourteen consecutive children (age range: 4 months to 11 years; median: 4 years) with acquired immunodeficiency syndrome (AIDS) were studied prospectively with cranial magnetic resonance imaging (MRI) and unenhanced computed tomography (CT). In 4 children, human immunodeficiency virus infection was transfusion-related
Quarterly communicable disease review April to June 1991. From the PHLS Communicable Disease Surveillance Centre.: J Public Health Med. 1991 Nov;13(4):332-41. Unique Identifier : AIDSLINE MED/92110073
Proteins of AIDS virus may link AIDS and Kaposi's sarcoma [news]: Dermatol Nurs. 1991 Dec;3(6):435. Unique Identifier : AIDSLINE MED/92110121
World AIDS Day: beyond myth and hysteria.: Nurs Stand. 1991 Nov 27-Dec 3;6(10):22-3. Unique Identifier : AIDSLINE MED/92110207; Tennant A
HIV and banked fascia lata.: Ophthal Plast Reconstr Surg. 1991;7(4):284-8. Unique Identifier : AIDSLINE MED/92110241; Bedrossian EH Jr; Wills Eye Hospital Fascia Lata Bank, Department of Ophthalmic; Plastic Surgery, Philadelphia, Pennsylvania 19107.; Concern over the transmission of communicable diseases through donor tissue has recently increased. Nine hundred and fifty-nine pieces of banked homologous irradiated fascia lata have been distributed to ophthalmic plastic surgeons nationwide over the past 3 years since the establishment of the Wills Eye Hospital Fasc
Tired of AIDS.: Tenn Nurse. 1991 Apr;54(2):12-5, 15, 17-8. Unique Identifier : AIDSLINE MED/92110250; Little M
Nashville CARES: providing hope & support [interview]: Tenn Nurse. 1991 Apr;54(2):16. Unique Identifier : AIDSLINE MED/92110251; Jackson L
Routine HIV serology.: Va Med Q. 1991 Fall;118(4):246. Unique Identifier : AIDSLINE MED/92110401; Kendig EL Jr
[Folates in human nutrition, Different clinical situations in which folate deficiencies exist]: Nutr Hosp. 1991 Jul-Aug;6(4):207-26. Unique Identifier : AIDSLINE MED/92110451; Zarazaga A; Garcia de Lorenzo A; Montanes P; Culebras JM; Servicio de Cirugia General, Hospital Universitario, La Paz,; Madrid.; The alimentary surveys carried out on various sectors of the population in industrialized countries have shown the existence of chronic clinically silent deficiency in micronutrients. In some cases, as in folates, their lability against conservation techniques, the change in alimentary habits, the abuse of alcohol and
Preparation of nucleoside-LDL-conjugates for the study of cell-selective internalization: stability characteristics and receptor affinity.: Eur J Clin Chem Clin Biochem. 1991 Oct;29(10):665-74. Unique Identifier : AIDSLINE MED/92110463; Schultis HW; von Baeyer H; Neitzel H; Riedel E; Institut fur Biochemie, Freie Universitat Berlin, Germany.; Antiviral therapy of human immunodeficiency virus (HIV) infection is currently based on inhibition of reverse transcriptase by dideoxynucleosides, such as azidothymidine. Because of widespread toxicity it is reasonable to selectively target these drugs to infected cells. This may be accomplished utilizing drug-LDL con
Incorporation of biotinylated nucleotides for the quantification of PCR-amplified HIV-1 DNA by chemiluminescence.: Eur J Clin Chem Clin Biochem. 1991 Oct;29(10):685-8. Unique Identifier : AIDSLINE MED/92110465; Bettens F; Pichler WJ; de Weck AL; Institut fur klinische Immunologie, Inselspital Bern.; Chemiluminescent detection of polymerase chain reaction (PCR-)amplified DNA was used as a quantitative method for detecting HIV-1. For this purpose, biotinylated dUMP was directly incorporated into the amplified DNA during the PCR reaction. Biotinylation was visualized in an enzymatic reaction using avidine-conjugated
Gastrointestinal emergencies in HIV infection.: Baillieres Clin Gastroenterol. 1991 Dec;5(4):887-911. Unique Identifier : AIDSLINE MED/92110642; Claydon EJ; Tanner A
Public education defuses cry for forced HIV testing.: Calif Nurse. 1991 Nov-Dec;87(10):3. Unique Identifier : AIDSLINE MED/92110684
[Caregivers and HIV]: Can Nurse. 1991 Dec;87(11):45. Unique Identifier : AIDSLINE MED/92110763; Savard N; An exploratory study conducted among 18 natural caregivers of persons with HIV revealed that extreme emotion was the results of the high cost of personal devotion.
[Evolution of the seroprevalence of HIV-1 and HIV-2 infections in the national hospital of Niamey, Niger]: Bull Soc Pathol Exot. 1991;84(3):235-9. Unique Identifier : AIDSLINE MED/92110874; Ousseini H; Pecarrere JL; Meynard D; Ahounou R; Adamou-Hassane; Directeur Programme National de Lutte contre le SIDA, Niamey,; Niger.; For 25,368 serologies examined in the biological laboratory of National Hospital of Niamey, Niger , from March 1987 to May 1990, the authors studied seroprevalence HIV1, HIV2 and HIV1 + HIV2 during this periode in the different groups studied: Blood donors, in women patients of child
[Seroprevalence of HIV-1 infections in patients consulting the clinic for sexually transmitted diseases in Bangui, Central African Republic]: Bull Soc Pathol Exot. 1991;84(3):240-6. Unique Identifier : AIDSLINE MED/92110875; Gresenguet G; Belec L; Martin PM; Georges AJ; Service National des Maladies Sexuellement Transmissibles,; Bangui, Republique Centrafricaine.; 140 consecutive African, exclusively heterosexual, adult outpatients to the Clinique des Maladies Sexuellement Transmissibles, with genital ulcers or urethritis, were studied in order to determine the status for HIV1-infection and syphilis. Comparison with 194 age and sex matched subjects, without STD, were chosen as
[A case of HTLV-1 associated myelopathy with diffuse white matter lesion of the frontal lobe and continuous lesion of the pyramidal tract on cranial MRI]: Rinsho Shinkeigaku. 1991 Aug;31(8):875-7. Unique Identifier : AIDSLINE MED/92111048; Konagaya M; Iida M; Department of Neurology, Suzuka National Hospital.; In this report, the characteristic findings of cranial MRI of a case with HTLV-1 associated myelopathy (HAM) is described. The patient was a 62-year-old woman with 6 years history of paraplegia. Her main clinical signs were bilateral spastic paraplegia in the lower limb girdle muscles and extremities, paresthesia belo
Psychosocial predictors of gay men's AIDS risk-reduction behavior.: Health Psychol. 1991;10(6):432-44. Unique Identifier : AIDSLINE MED/92111446; Aspinwall LG; Kemeny ME; Taylor SE; Schneider SG; Dudley JP; University of California, Los Angeles 90024.; Used psychosocial variables derived from the health belief model (Rosenstock, 1974), Bandura s (1986) self-efficacy framework, and protection motivation theory (Rogers, 1984) to predict self-reported AIDS risk-reduction behaviors in a sample of 389 homosexual men who participated in the Multicenter AIDS Cohort Study i
The epidemiology of HIV infection in children and their mothers--vertical transmission.: Epidemiol Rev. 1991;13:143-77. Unique Identifier : AIDSLINE MED/92111656; Boylan L; Stein ZA; HIV Center for Clinical and Behavioral Studies, New York State; Psychiatric Institute, School of Public Health, NY.
The epidemiology of classic, African, and immunosuppressed Kaposi's sarcoma.: Epidemiol Rev. 1991;13:178-99. Unique Identifier : AIDSLINE MED/92111657; Wahman A; Melnick SL; Rhame FS; Potter JD; Division of Epidemiology, School of Public Health, University of; Minnesota, Minneapolis 55454-1015.; The etiology of Kaposi s sarcoma remains somewhat obscure. While lesions of classic Kaposi s sarcoma, African Kaposi s sarcoma, and immunosuppressed Kaposi s sarcoma have been found to be indistinguishable from one another, the reasons for the variations in type and severity have not been established. The origin of th
A novel alternatively spliced viral mRNA transcribed in cells infected with human T cell leukemia virus type 1 is mainly responsible for expressing p21X protein [published erratum appears in FEBS Lett 1992 Mar 24;299(1):117]: FEBS Lett. 1991 Dec 16;295(1-3):127-34. Unique Identifier : AIDSLINE MED/92111722; Orita S; Saiga A; Takagi S; Tanaka T; Okumura K; Aono Y; Hinuma Y; Igarashi H; Shionogi Institute for Medical Science, Osaka, Japan.; The pX sequence of human T cell leukemia virus type 1 (HTLV-1) has been thought to be expressed as a doubly spliced mRNA that codes for p40tax, p27rex and p21X. However, we identified a novel alternatively spliced mRNA in the HTLV-1 infected cells by using reverse transcription followed by the polymerase chain reactio
Alternatively spliced mRNA of the pX region of human T lymphotropic virus type I proviral genome.: FEBS Lett. 1991 Dec 16;295(1-3):141-5. Unique Identifier : AIDSLINE MED/92111725; Furukawa K; Furukawa K; Shiku H; Department of Oncology, Nagasaki University School of Medicine,; Japan.; The pX region of human T lymphotropic virus type I (HTLV-I) is believed to be expressed as a consequence of a 2 step splicing. It is conceivable, however, that a donor site of the 1st splicing and an acceptor site of the 2nd splicing results in the production of an alternatively spliced mRNA which is capable of coding
Reluctance to care for patients with AIDS [letter]: Gen Hosp Psychiatry. 1991 Nov;13(6):410. Unique Identifier : AIDSLINE MED/92112006; Blumenfield M; Milazzo J; Wormser GP; Smith PJ
Zigzaids--an educational game about AIDS for children.: Hygie. 1991;10(4):32-5. Unique Identifier : AIDSLINE MED/92112235; Monteiro SS; Rebello SM; Schall VT; Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, Brazil.; In spite of the progress made in treating the different opportunistic illness in HIV syndrome, prevention remains the only real answer we have in stopping the spread of this disease. Programmes using new, innovative and interactive materials are necessary to reach a maximum number of people.
The birth of the WHO/GPA Regional AIDS Information Exchange Resource Centre; African Regional Health Education Centre, University of Ibadan, Nigeria [news]: Hygie. 1991;10(4):49-50. Unique Identifier : AIDSLINE MED/92112238; Olaseha IO; Adeniyi JD
Pooling resources for HIV/AIDS orphans [news]: Int Nurs Rev. 1991 Nov-Dec;38(6):164. Unique Identifier : AIDSLINE MED/92112402
Rampant HIV spread in developing countries [news]: Int Nurs Rev. 1991 Nov-Dec;38(6):168. Unique Identifier : AIDSLINE MED/92112404
Switzerland: an innovative AIDS prevention campaign [news]: Int Nurs Rev. 1991 Nov-Dec;38(6):168-9. Unique Identifier : AIDSLINE MED/92112405
Latex--a new cause of anaphylaxis.: Iowa Med. 1991 Oct;81(10):439-40. Unique Identifier : AIDSLINE MED/92112465; Caudill G; Zivkovich V; U. of I. Department of Pediatrics, Des Moines.; Increased use of latex gloves and condoms as protection against HIV could increase incidence of anaphylactic reaction, say these authors. Contact with latex during an examination, catheterization, delivery or surgery can also cause an anaphylaxis in some patients.
AIDS & entrepreneurs [news]: Hastings Cent Rep. 1991 Nov-Dec;21(6):2-3. Unique Identifier : AIDSLINE MED/92112479; Nelson HL
Please don't tell!: Hastings Cent Rep. 1991 Nov-Dec;21(6):39; discussion 39-40. Unique Identifier : AIDSLINE MED/92112483; Fleck L; Angell M; Center for Ethics and Humanities in the Life Sciences, Michigan; State University, East Lansing.
The patient's choice [news]: Hastings Cent Rep. 1991 Nov-Dec;21(6):4. Unique Identifier : AIDSLINE MED/92112485; Crigger BJ
About face [news]: Hastings Cent Rep. 1991 Nov-Dec;21(6):47. Unique Identifier : AIDSLINE MED/92112488
[Detection of causal agents of AIDS using polymerase chain reaction and chemiluminescence measurement]: Hautarzt. 1991 Dec;42(12):754-8. Unique Identifier : AIDSLINE MED/92112513; Schmidt BL; Gschnait F; Ludwig Boltzmann-Institut fur dermato-venerologische; Serodiagnostik Wien.; The polymerase chain reaction (PCR) allows the detection of minimal amounts of DNA segments, and thus is used for the laboratory diagnosis of HIV (human immunodeficiency virus). In the present study a solution hybridization assay using acridinium ester-labelled probes was applied for detection of amplified HIV-1 DNA s
HIV/AIDS prevention [letter]: Health Visit. 1991 Sep;64(9):311. Unique Identifier : AIDSLINE MED/92112588; Smith A
Public response to announcement of an HIV positive dental student.: J Dent Educ. 1991 Dec;55(12):777-80. Unique Identifier : AIDSLINE MED/92113147; Pashley EL; Comer RW; McCoy BP; Myers DR; Department of Oral Diagnosis and Patient Services, Medical; College of Georgia, School of Dentistry, Augusta 30912.
Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system.: J Immunol Methods. 1991 Dec 15;145(1-2):229-40. Unique Identifier : AIDSLINE MED/92113306; Karlsson R; Michaelsson A; Mattsson L; Pharmacia Biosensor AB, Uppsala, Sweden.; An automated biosensor system for measuring molecular interactions has been used to study the kinetics of monoclonal antibody-antigen reactions. The system combines a microfluidic unit in contact with a sensor surface for surface plasmon resonance detection. The specificity of the surface is determined by the operator
Acquired memory insufficiency syndrome.: J Fla Med Assoc. 1991 Nov;78(11):771. Unique Identifier : AIDSLINE MED/92113514; Brouillette JN
Long-term care preferences of hospitalized persons with AIDS.: J Gen Intern Med. 1991 Nov-Dec;6(6):524-8. Unique Identifier : AIDSLINE MED/92113772; McCormick WC; Inui TS; Deyo RA; Wood RW; University of Washington, Harborview Medical Center, Seattle; 98104.; OBJECTIVE: To determine in a cohort of hospitalized persons with AIDS: 1) their preferences for various postdischarge long-term care settings, 2) the postdischarge settings recommended by primary care providers (doctors, nurses, and social workers), and 3) the impact of these views on the resulting discharge dispositi
Counseling issues in methadone maintenance treatment.: J Psychoactive Drugs. 1991 Apr-Jun;23(2):177-90. Unique Identifier : AIDSLINE MED/92113798; Zweben JE; 14th Street Clinic and Medical Group, Oakland, California.; This article reviews some of the issues and dilemmas faced by methadone maintenance treatment (MMT) programs counselors. The context in which MMT occurs sets the tone and constraints within which clinicians must find ways to be effective; negative attitudes and tensions with regulatory agencies have a strong impact. C
Human T-cell lymphotrophic virus in California's injection drug users.: J Psychoactive Drugs. 1991 Apr-Jun;23(2):225-32. Unique Identifier : AIDSLINE MED/92113802; Trachtenberg AI; Gaudino JA; Hanson CV; Bureau of Drug Abuse Services, Santa Clara County Public Health; Department, San Jose, California.; Human T-cell lymphotrophic virus I (HTLV-I) and human T-cell lymphotrophic virus II (HTLV-II) are closely related retroviruses that are highly prevalent in injection drug users (IDUs). The bulk of infection in this group probably occurs with HTLV-II, with a lower prevalence of HTLV-I. HTLV-I is known to cause adult T-
Results of a prenatal screening program for the human immunodeficiency virus in a cross-sectional population.: J Reprod Med. 1991 Nov;36(11):773-8. Unique Identifier : AIDSLINE MED/92113962; Horowitz GM; Scott RT; Hankins GD; Department of Obstetrics and Gynecology, Wilford Hall United; States Air Force Medical Center, Lackland Air Force Base, Texas; 78236-5300.; A prenatal screening program for antibody to the human immunodeficiency virus (HIV) was examined prospectively in a cross-sectional population. Routine screening was performed on 3,241 women during the first trimester. Serum samples yielding repeatedly positive results on an enzyme-linked immunosorbent assay (ELISA) (
Rheumatic manifestations in populations at risk for HIV infection: the added effect of HIV.: J Rheumatol. 1991 Oct;18(10):1564-7. Unique Identifier : AIDSLINE MED/92114001; Berman A; Reboredo G; Spindler A; Lasala ME; Lopez H; Espinoza LR; Department of Medicine, Tucumah University School of Medicine,; General San Martin and Angel C. Padilla Hospital, Buenos Aires.; We assessed the frequency and variability of rheumatologic manifestations in 2 populations with similar risk factors for human immunodeficiency virus (HIV) infection, of which only one was affected. We studied 2 populations at risk for HIV infection (homosexual and intravenous drug users). Group A: 89 individuals carr
Examination of HIV-1 protease secondary structure specificity using conformationally constrained inhibitors.: J Med Chem. 1991 Dec;34(12):3395-9. Unique Identifier : AIDSLINE MED/92114030; Kahn M; Nakanishi H; Chrusciel RA; Fitzpatrick D; Johnson ME; Department of Chemistry, University of Illinois, Chicago 60680.
Novel alkaloids from the tropical plant Ancistrocladus abbreviatus inhibit cell killing by HIV-1 and HIV-2.: J Med Chem. 1991 Dec;34(12):3402-5. Unique Identifier : AIDSLINE MED/92114032; Manfredi KP; Blunt JW; Cardellina JH 2d; McMahon JB; Pannell LL; Cragg GM; Boyd MR; Laboratory of Drug Discovery Research and Development, National; Cancer Institute, Frederick, Maryland 21702-1201.
Absolute CD4 count as a predictor for Mycobacterium avium infection in AIDS patients [letter]: J Natl Med Assoc. 1991 Nov;83(11):943. Unique Identifier : AIDSLINE MED/92114087; Jordan WC
Dumping HIV-infected patients from private practice.: J Natl Med Assoc. 1991 Nov;83(11):961-5. Unique Identifier : AIDSLINE MED/92114092; Isaacman SH; John Marshall Law School, Chicago, Illinois 60604.; Physicians in private practice believe they have the freedom to accept or exclude patients. While this may be true on an individual basis, discrimination towards a patient subpopulation violates professional principles and the law. Once the doctor-patient relationship is formed, physicians may not unilaterally and arb
Ultrasound diagnosis of hepatic Kaposi sarcoma.: J Ultrasound Med. 1991 Dec;10(12):701-3. Unique Identifier : AIDSLINE MED/92114119; Towers MJ; Withers CE; Rachlis AR; Pappas SC; Kolin A; Department of Radiological Sciences, Sunnybrook Health Science; Centre, University of Toronto, Ontario, Canada.
Resolution approved November 15, 1991 MNA Convention. HIV testing for professionals.: Md Nurse. 1991 Nov-Dec;10(8):1. Unique Identifier : AIDSLINE MED/92114541
The patient had AIDS: facing my fears.: Md Nurse. 1991 Nov-Dec;10(8):10. Unique Identifier : AIDSLINE MED/92114542; Garnand R
AIDS protection is patient's right [interview]: Md Nurse. 1991 Nov-Dec;10(8):6. Unique Identifier : AIDSLINE MED/92114543; Joel L
Mandatory HIV testing for nurses: yes or no?: Md Nurse. 1991 Nov-Dec;10(8):6. Unique Identifier : AIDSLINE MED/92114544; Pannell J
Testing HCWs: a public misconception.: Md Nurse. 1991 Nov-Dec;10(8):6. Unique Identifier : AIDSLINE MED/92114545; Mallinson K
[Prevalence of infection by the human immunodeficiency virus type 1 in drug addicts in Madrid, over a 5 year period]: Med Clin (Barc). 1991 Nov 9;97(16):601-3. Unique Identifier : AIDSLINE MED/92114546; Sopelana P; Dieguez A; Bautista L; Unidad de Desintoxicacion de Drogodependientes, Hospital; Psiquiatrico de Madrid.; BACKGROUND: Firstly, to evaluate the annual levels of seroprevalence of antibodies against the type I human immunodeficiency virus in a sample of 1,232 intravenous drug users (IVDU) admitted for treatment to a hospital detoxication unit i Madrid over a period of 5 years. Secondly, attempt to distinguish the existence
[Cryptococcosis of the central nervous system. Clinical and diagnostic characteristics]: Med Clin (Barc). 1991 Nov 9;97(16):604-8. Unique Identifier : AIDSLINE MED/92114547; Jimenez-Mejias ME; Fernandez A; Alfaro E; Regordan C; Pachon Diaz J; Unidad de Enfermedades Infecciosas (Departamento de Medicina; Interna), Hospital Universitario Virgen del Rocio, Sevilla.; BACKGROUND: Evaluation of the clinical features and diagnostic methods in the cryptococcosis of central nervous system (CNS), so as to facilitate a rapid recognition which may result in earlier diagnosis in view of the rapid increase in frequency shown in that condition. METHODS: A retrospective study of 13 patients w
[Obliterating bronchiolitis in a patient with human immunodeficiency virus infection (letter)]: Med Clin (Barc). 1991 Nov 9;97(16):638. Unique Identifier : AIDSLINE MED/92114560; Laguna del Estal P; Martin T; Martin F; Lopez E
Intraoperative infectious disease exposure to otolaryngology operating room personnel.: Laryngoscope. 1991 Dec;101(12 Pt 1):1276-9. Unique Identifier : AIDSLINE MED/92114625; Benninger MS; Gupta N; Gilmore K; Department of Otolaryngology, Henry Ford Hospital, Detroit, MI; 48202.; Health care workers are at risk of exposure to serious infectious diseases. Since the seroconversion rate is approximately 0.4% for human immunodeficiency virus and may be greater than 20% for hepatitis exposure, these risks are substantial. To assess body fluid exposure to otolaryngology operating room personnel, ele
GDAHC studies offer new insights into AIDS care [news]: Mich Med. 1991 Dec;90(12):9. Unique Identifier : AIDSLINE MED/92114815
MNA opposes mandatory AIDS testing.: Mich Nurse. 1991 Aug;64(7):5. Unique Identifier : AIDSLINE MED/92114824
Oxidative imbalance in HIV infected patients.: Med Hypotheses. 1991 Sep;36(1):60-4. Unique Identifier : AIDSLINE MED/92114836; Fuchs J; Ochsendorf F; Schofer H; Milbradt R; Rubsamen-Waigmann H; Zentrum der Dermatologie und Venerologie, Johann Wolfgang Goethe; Universitat, Frankfurt/M, Germany.; We present an outline of the complex interplay of oxidants and antioxidants in infectious diseases in general, and in particular with reference to the HIV infection, and subsequent opportunistic infections. Viral and opportunistic infections may directly or indirectly cause an imbalance in prooxidant/antioxidant mecha
Sexually transmitted infections on the increase [news]: Nurs RSA. 1991 Oct;6(10):47. Unique Identifier : AIDSLINE MED/92114926
[AIDS in Italy]: Minerva Chir. 1991 Oct 31;46(20):1150-1. Unique Identifier : AIDSLINE MED/92115130; Di Nola F
[Several aspects of HIV infections]: Minerva Chir. 1991 Oct 31;46(20):1152. Unique Identifier : AIDSLINE MED/92115132; Costantino M
[Serology study for HBV and HIV-1 in a cohort of parenteral drug addicts]: Minerva Med. 1991 Nov;82(11):771-3. Unique Identifier : AIDSLINE MED/92115145; Mauri R; Fumagalli S; Durello R; Nucleo Operativo Tossicodipendenze (NOT), USL n. 67, Bollate,; Milano.; We studied 335 subjects, all drug addicts for the presence of the following serological markers: HIV1 antibody, HBsAg, HBsAb, HBcAb totals. We conclude that subjects HIV1 positive (n. 149) present HBsAb in a significantly lower number (p greater than 0.001) than HIV1 negative subjects (n. 95). The presence of HBcAb is
[AIDS in Italy]: Minerva Med. 1991 Nov;82(11):786-7. Unique Identifier : AIDSLINE MED/92115148; Di Nola F
[AIDS in the world]: Minerva Med. 1991 Nov;82(11):787-8. Unique Identifier : AIDSLINE MED/92115149; Di Nola F
[Various aspects of the therapy of HIV infections]: Minerva Med. 1991 Nov;82(11):788. Unique Identifier : AIDSLINE MED/92115150; Costantino M
[AIDS in Italy (news)]: Minerva Ginecol. 1991 Oct;43(10):490-1. Unique Identifier : AIDSLINE MED/92115162; Di Nola F
[AIDS around the world (news)]: Minerva Ginecol. 1991 Oct;43(10):491-2. Unique Identifier : AIDSLINE MED/92115163; Di Nola F
Determination of cadaveric antibody against HIV in vitreous humor of HIV-positive patients: potential use in corneal transplantation.: Ophthalmologica. 1991;203(1):12-6. Unique Identifier : AIDSLINE MED/92115280; Grupenmacher F; Silva FM; Abib FC; Grupenmacher L; Silva AC; de Almeida PT; Department of Ophthalmology, Federal University of Parana,; Brazil.; The authors suggest the determination of antibody against HIV in vitreous humor as a screening technique for AIDS carriers, specially in cases of corneal transplantation when the eye bank could make the examinations required and in cases when drawing blood after death becomes difficult. Ten eyes of patients having die
Daytime edema levels with plus powered low and high water content hydrogel contact lenses.: Optom Vis Sci. 1991 Nov;68(11):877-80. Unique Identifier : AIDSLINE MED/92115294; La Hood D; Cornea and Contact Lens Research Unit, School of Optometry,; University of New South Wales, Sydney, Australia.; Eleven unadapted contact lens wearers wore a high (74%) water content hydrogel lens (Permaflex, CooperVision) of oxygen transmissibility Dk/Lav 14 x 10(-9) in one eye and a low (43%) water content hydrogel lens (Aquaflex Superthin) of Dk/Lav 4 x 10(-9) in the other eye under open-eye conditions for 8 h. After 8 h, ave
HTLV-1 Tax has distinct but overlapping domains for transcriptional activation and for enhancer specificity.: Oncogene. 1991 Dec;6(12):2349-52. Unique Identifier : AIDSLINE MED/92115339; Fujii M; Tsuchiya H; Seiki M; Department of Virology, Cancer Research Institute, Ishikawa,; Japan.; Tax1 of human T-cell leukemia virus type 1 (HTLV-1) activates viral transcription dependent upon three 21-bp enhancer elements in the long terminal repeat. Difficulties in detecting any association of Tax1 with the viral enhancer have hampered elucidation of the molecular mechanisms of Tax1-mediated transcriptional ac
Disseminated fungal infections in children infected with human immunodeficiency virus.: Pediatr Infect Dis J. 1991 Dec;10(12):888-94. Unique Identifier : AIDSLINE MED/92115373; Leibovitz E; Rigaud M; Chandwani S; Kaul A; Greco MA; Pollack H; Lawrence R; Di John D; Hanna B; Krasinski K; et al; Department of Pediatrics, New York University Medical; Center/Bellevue Hospital Center, NY 10016.; A retrospective review of charts of 156 human immunodeficiency virus-infected children cared for during a 7.5-year period revealed 11 episodes of disseminateed candidiasis (DC) occurring in 11 patients (7%). All 11 patients developed the fungal infection in the context of advanced human immunodeficiency virus infectio
Pneumocystis carinii pneumonia in a human immunodeficiency virus 1-infected neonate with meconium aspiration.: Pediatr Infect Dis J. 1991 Dec;10(12):953-5. Unique Identifier : AIDSLINE MED/92115387; Beach RS; Garcia ER; Sosa R; Good RA; Division of Neonatology, Broward General Medical Center, Ft.; Lauderdale, FL.
Normative data for a brief neuropsychological screening battery. Multicenter AIDS Cohort Study.: Percept Mot Skills. 1991 Oct;73(2):539-50. Unique Identifier : AIDSLINE MED/92115458; Selnes OA; Jacobson L; Machado AM; Becker JT; Wesch J; Miller EN; Visscher B; McArthur JC; This study reports normative data for a group of 733 homosexual/bisexual men stratified by age (range 25 to 54 years) and by education on the following six neuropsychological tests: (1) Digit Span (WAIS-R), (2) Rey Auditory Verbal Learning Test, (3) Symbol Digit Modalities Test, (4) Controlled Oral Word Association Te
Routines for endoscopes [letter]: Nurs Times. 1991 Dec 11-17;87(50):12. Unique Identifier : AIDSLINE MED/92115579; Bottrill P
Onus on workers to get help for HIV [news]: Nurs Times. 1991 Dec 11-17;87(50):5. Unique Identifier : AIDSLINE MED/92115597; Carlisle D
AIDS vaccines [editorial]: Public Health. 1991 Jul;105(4):273-5. Unique Identifier : AIDSLINE MED/92115822; Dunlop JM
Computer skills course integrates AIDS education.: Radiol Technol. 1991 Nov-Dec;63(2):100-4. Unique Identifier : AIDSLINE MED/92115846; Walker PW; Stewart CK; Avdevich CK; University of Louisville, Ky 40292.; Health professionals play an important role in educating the public about AIDS and HIV patient and community health education. This article describes an innovative approach incorporating AIDS education into a basic skills course covering statistical computing, computerized literature searches and modeling.
Educating the public about AIDS [letter]: Radiol Technol. 1991 Nov-Dec;63(2):89. Unique Identifier : AIDSLINE MED/92115849; Hammrich H
[Immunologic evaluation of 246 HIV patients]: Rev Med Panama. 1991 Sep;16(3):173-83. Unique Identifier : AIDSLINE MED/92115868; Diaz-Isaacs M; Vernaza A; de Gomez IJ; Lozano L; de los Reyes Cano M; Servicio de Inmunologia y Alergia, Hospital Metropolitano; Arnulfo Arias Madrid.; The authors report the results of the immunological studies carried out on 246 individuals infected with the human immunodeficiency virus (HIV) in order to compare these data with those obtained in a previous study. They demonstrate an appreciable increase in the number of women with HIV infection and the change of th
[Risk of exposure to blood (news)]: Rev Infirm. 1991 Oct 17;41(16):15. Unique Identifier : AIDSLINE MED/92116076
[AIDS: the difficult elaboration of a vaccine]: Rev Infirm. 1991 Nov 7;41(17):44-6. Unique Identifier : AIDSLINE MED/92116098; Bourgault I
[Drug addicts with AIDS. The nurse facing conflict situations]: Rev Enferm. 1991 Nov;14(159):21-5. Unique Identifier : AIDSLINE MED/92116104; Salvador Roig C
Social disintegration and the spread of AIDS: thresholds for propagation along 'sociogeographic' networks.: Soc Sci Med. 1991;33(10):1155-62. Unique Identifier : AIDSLINE MED/92116185; Wallace R; Epidemiology of Mental Disorders Research Department, New York; State Psychiatric Institute, NY 10032.; Previous work on the asymptotic spread of HIV infection along a low dimensional sociogeographic network--a social network characteristically embedded within a limited geographic area--is extended to explore threshold conditions under which the infection extends widely beyond an initial set of infected individuals or
[Sanctuary for HIV-positive patients]: Sygeplejersken. 1991 Jul 3;91(27):21. Unique Identifier : AIDSLINE MED/92116315; Jensen IM
[AIDS--a spoke in the system]: Sygeplejersken. 1991 Jul 10;91(28):13. Unique Identifier : AIDSLINE MED/92116324; Kjaergaard G
[The 1st case of adult T-cell leukemia (ATL) with expressed immune response to HTLV in the USSR]: Vopr Onkol. 1991;37(5):563-8. Unique Identifier : AIDSLINE MED/92116523; Gurtsevich VE; Seniuta NB; Pivnik AV; Pavlish OA; Stepina VN; Syrtsev AV; Iakhnina EI; Kremenetskaia AM; The first of case of adult T-cell prolymphocytic lymphosarcoma is reported which according to the natural course, cell composition of tumor, cell surface markers as well as expressed immune response to a wide spectrum of HTLV-1 gag an env encoded proteins can be classified as HTLV-associated adult T-cell leukemia. Dia
[Immunosorption of individual HIV proteins and virions]: Vestn Akad Med Nauk SSSR. 1991;(11):60-3. Unique Identifier : AIDSLINE MED/92116625; Lopukhin IuM; Pavlenko VV; Kulaev DV; Liukova TK; Petrunin DD; Karamov EV; Rudneva IA; Immunosorbents specifically binding native (gp160, gp120, gp41) and recombinant env proteins and HIV-I virions were synthesized on the basis of Sepharose 4B and Silica with immobilized ligands such as gamma-fraction of rabbit antiserum to HIV-I proteins and purified antibodies to env proteins of HIV-I. The possibility
Reflections of an AIDS doctor [editorial]: J Am Board Fam Pract. 1991 Nov-Dec;4(6):473-4. Unique Identifier : AIDSLINE MED/92116796; Carmichael JK
Post-transfusion purpura [letter; comment]: J Am Board Fam Pract. 1991 Nov-Dec;4(6):477. Unique Identifier : AIDSLINE MED/92116797; Greenway J
HIV guidelines may spur lawsuits.: AORN J. 1991 Dec;54(6):1164. Unique Identifier : AIDSLINE MED/92117522
Separation and detection of DNA polynucleotides using capillary electrophoresis. Application to detection of polymerase chain reaction-amplified human immunodeficiency virus and HLA DNA.: Arch Pathol Lab Med. 1991 Dec;115(12):1228-34. Unique Identifier : AIDSLINE MED/92117841; Mayer A; Sunzeri F; Lee TH; Busch MP; Irwin Memorial Blood Centers, San Francisco, Calif.; The polymerase chain reaction (PCR) is a technique for rapid amplification of target DNA sequences. During the past several years, a large number of research applications of PCR have appeared, many of which may prove to be useful clinically. We report the use of capillary electrophoresis, a fully automated technique,
Condemnation of homosexuality in the black community: a gender-specific phenomenon?: Arch Sex Behav. 1991 Dec;20(6):579-85. Unique Identifier : AIDSLINE MED/92117858; Ernst FA; Francis RA; Nevels H; Lemeh CA; Department of Family and Preventive Medicine, Meharry Medical; College, Nashville, Tennessee 37208.; While it is commonly accepted that homosexuality finds less tolerance in the black community, little or no research has addressed this issue empirically. In the context of an epidemiological investigation of AIDS-related attitudes, 2006 state employees were surveyed to compare the condemnatory orientation of blacks an
Inhibition of AIDS virus replication by acemannan in vitro.: Mol Biother. 1991 Sep;3(3):127-35. Unique Identifier : AIDSLINE MED/92118241; Kahlon JB; Kemp MC; Carpenter RH; McAnalley BH; McDaniel HR; Shannon WM; Southern Research Institute, Birmingham, AL.; Acemannan (ACE-M), a beta-(1,4)-linked acetylated mannan, was evaluated for in vitro activity against human immunodeficiency virus type 1 (HIV-1). Castanospermine (CAS), deoxymannojirimycin (DMN), swainsonine (SWS), azidothymidine ( AZT ), and dideoxyth
The natural history of HIV and AIDS in women [editorial]: AIDS. 1991 Nov;5(11):1283-92. Unique Identifier : AIDSLINE MED/92118254; Brettle RP; Leen CL
Identification of mixed HIV-1/HIV-2 infections in Brazil by polymerase chain reaction.: AIDS. 1991 Nov;5(11):1293-9. Unique Identifier : AIDSLINE MED/92118255; Pieniazek D; Peralta JM; Ferreira JA; Krebs JW; Owen SM; Sion FS; Filho CF; Sereno AB; de Sa CA; Weniger BG; et al; Division of HIV/AIDS, Centers for Disease Control, Atlanta, GA; 30333.; Analysis of sera from hospitalized Brazilian patients by whole-virus lysate-based enzyme immunoassay and Western blot indicated that 0.4% were reactive to HIV-2 alone while 4% were reactive to both HIV-1 and HIV-2. When these sera were tested for HIV antibody by type-specific peptide enzyme immunoassays, dual seroposi
HIV-1 Nef protein exhibits structural and functional similarity to scorpion peptides interacting with K+ channels.: AIDS. 1991 Nov;5(11):1301-8. Unique Identifier : AIDSLINE MED/92118256; Werner T; Ferroni S; Saermark T; Brack-Werner R; Banati RB; Mager R; Steinaa L; Kreutzberg GW; Erfle V; GSF Forschungszentrum fur Umwelt und Gesundheit, Neuherberg,; Germany.; The persistent infection of human glial cells with HIV-1 is characterized by prominent expression of the Nef protein. In order to evaluate the possible role of Nef in the development of HIV-1-associated neurological disorders, we compared Nef with known neuroactive proteins. We found that HIV Nef shares sequence and s
Immunoglobulin G3-specific antibodies as a marker for early diagnosis of HIV infection in children.: AIDS. 1991 Nov;5(11):1315-8. Unique Identifier : AIDSLINE MED/92118258; Arico M; Caselli D; Marconi M; Avanzini MA; Colombo A; Pasinetti G; Maccabruni A; Rondanelli EG; Burgio GR; Department of Paediatrics, University of Pavia, IRCCS Policlinico; S. Matteo, Italy.; Early diagnosis of HIV infection in the child of an HIV-infected mother may be difficult as HIV-specific immunoglobulin (Ig) G antibodies are transmitted to the fetus transplacentally. In an attempt to provide a new, simpler tool for early identification of HIV-infected children we analysed the HIV-specific IgG subcla
Serum interleukin-6 concentrations are elevated and associated with elevated tumor necrosis factor-alpha and immunoglobulin G and A concentrations in children with HIV infection.: AIDS. 1991 Nov;5(11):1319-25. Unique Identifier : AIDSLINE MED/92118259; Rautonen J; Rautonen N; Martin NL; Philip R; Wara DW; Department of Pediatrics, University of California, San Francisco; 94143-0544.; Hypergammaglobulinemia is one of the most consistent, and usually the first observable abnormality in infants vertically infected with HIV. We have analyzed serum interleukin (IL)-4, IL-6, tumor necrosis factor (TNF)-alpha, and immunoglobulin (Ig) concentrations in 23 HIV-infected and 21 uninfected children. IL-6 and
Differences in the expression of histocompatibility antigen-DR and in anti-mycobacterial activity of monocytes from HIV-infected individuals.: AIDS. 1991 Nov;5(11):1327-32. Unique Identifier : AIDSLINE MED/92118260; Zwilling BS; Salkowitz J; Laufman H; Pearl D; Department of Microbiology, Ohio State University, Columbus.; This study assesses the changes in the expression of histocompatibility antigen (HLA)-DR by mononuclear phagocytes from HIV-infected individuals. Overnight culture of monocytes resulted in an increase in HLA-DR expression by monocytes from uninfected individuals. In contrast, the expression of HLA-DR by monocytes from
Oral candidiasis in HIV infection: pseudomembranous and erythematous candidiasis show similar rates of progression to AIDS.: AIDS. 1991 Nov;5(11):1339-43. Unique Identifier : AIDSLINE MED/92118262; Dodd CL; Greenspan D; Katz MH; Westenhouse JL; Feigal DW; Greenspan JS; Oral AIDS Center, University of California San Francisco; 94143-0512.; Candidiasis is the most common oral fungal infection seen in association with HIV infection. It may present in a number of clinical forms, including pseudomembranous and erythematous candidiasis. To determine whether erythematous candidiasis, like the pseudomembranous form, is predictive of the development of AIDS, we
Lack of compensatory megakaryocytopoiesis in HIV-1-seropositive thrombocytopenic individuals compared with immune thrombocytopenic purpura patients.: AIDS. 1991 Nov;5(11):1345-50. Unique Identifier : AIDSLINE MED/92118263; Zauli G; Re MC; Gugliotta L; Visani G; Vianelli N; Furlini G; La Placa M; Institute of Microbiology, University of Bologna, Italy.; In this study we demonstrate that HIV-1-seropositive thrombocytopenic individuals, in contrast with immune thrombocytopenic purpura (ITP) patients, fail to have a compensatory increase of megakaryocytopoiesis. The in vitro growth of bone-marrow megakaryocyte progenitors (CFU-MK) and the production of granulocyte/macro
HIV-seropositive thrombocytopenia: the action of zidovudine.: AIDS. 1991 Nov;5(11):1351-6. Unique Identifier : AIDSLINE MED/92118264; Boyar A; Beall G; Department of Medicine, Harbor-University of California Los; Angeles Medical Center, Torrance 90509.; The action of zidovudine when administered to individuals with severe HIV thrombocytopenia was investigated. Four individuals with platelets less than 50 x 10(9)/l and CD4 cells greater than 200 x 10(6)/l were treated with 600 mg zidovudine per day for 6 weeks, no drug for 6 weeks, 1200 mg zidovudine per day for 6 wee
The long-term use of zidovudine in patients with severe immune-mediated thrombocytopenia secondary to infection with HIV.: AIDS. 1991 Nov;5(11):1357-61. Unique Identifier : AIDSLINE MED/92118265; Rarick MU; Espina B; Montgomery T; Easley A; Allen J; Levine AM; Department of Internal Medicine, USC School of Medicine, Los; Angeles 90033.; Various treatments for HIV-related thrombocytopenia have been reported. Since etiologies of the thrombocytopenia may differ with regard to risk group treatment outcomes may also vary. We have recently studied the long-term use of zidovudine in individuals with sexually transmitted HIV infection and severe thrombocytop
Toxoplasma serology, parasitemia and antigenemia in patients at risk for toxoplasmic encephalitis.: AIDS. 1991 Nov;5(11):1363-5. Unique Identifier : AIDSLINE MED/92118266; Dannemann BR; Israelski DM; Leoung GS; McGraw T; Mills J; Remington JS; Research Institute, Palo Alto Medical Foundation Research; Institute, CA 94301.; In order to further characterize the pathogenesis of Toxoplasma gondii infection in patients with AIDS and AIDS-related complex (ARC), a cohort of HIV- and Toxoplasma-infected individuals were identified and prospectively followed. Four hundred and 10 HIV-infected individuals followed in the San Francisco General Hosp
AIDS in rural eastern North Carolina--patient migration: a rural AIDS burden.: AIDS. 1991 Nov;5(11):1373-8. Unique Identifier : AIDSLINE MED/92118268; Rumley RL; Shappley NC; Waivers LE; Esinhart JD; Department of Medicine, Carolina University School of Medicine,; Greenville, NC 27858-4354.; A descriptive retrospective study on the AIDS and HIV patients of rural eastern North Carolina was performed. Our data show what appears to be a second wave of HIV-related disease (HRD) in this area. Although most of our AIDS and HIV patients migrated from urban areas such as New York State, our patient population i
The need for rigorous molecular epidemiology [editorial]: AIDS. 1991 Nov;5(11):1379-80. Unique Identifier : AIDSLINE MED/92118269; Busch MP
Differential effect of serum on syncytium formation and virus production in cells chronically infected with HIV in vitro [letter]: AIDS. 1991 Nov;5(11):1386-8. Unique Identifier : AIDSLINE MED/92118272; Ushijima H; Unten S; Honma H; Tsuchie H; Kitamura T; Weiler BE; Muller WE
The inhibitory effects of suramin on HIV-1 are attenuated in the presence of albumin [letter]: AIDS. 1991 Nov;5(11):1389-91. Unique Identifier : AIDSLINE MED/92118274; Yao XJ; Wainberg MA; Pollak M
Field evaluation of immunoglobulin G antibody capture tests for HIV-1 and HIV-2 antibodies in African serum, saliva and urine [letter]: AIDS. 1991 Nov;5(11):1391-2. Unique Identifier : AIDSLINE MED/92118275; Klokke AH; Ocheng D; Kalluvya SE; Nicoll AG; Laukamm-Josten U; Parry JV; Mortimer PP; Connell JA
Respiratory insufficiency from dapsone-induced methemoglobinemia [letter]: AIDS. 1991 Nov;5(11):1392-3. Unique Identifier : AIDSLINE MED/92118276; Gallant JE; Hoehn-Saric E; Smith MD
Microsporidiosis detected in association with AIDS-related sclerosing cholangitis [letter]: AIDS. 1991 Nov;5(11):1394-5. Unique Identifier : AIDSLINE MED/92118277; McWhinney PH; Nathwani D; Green ST; Boyd JF; Forrest JA
Zidovudine-associated hypertrichosis and nail pigmentation in an HIV-infected patient [letter]: AIDS. 1991 Nov;5(11):1395-6. Unique Identifier : AIDSLINE MED/92118278; Sahai J; Conway B; Cameron D; Garber G
Interrater reliability of the Karnofsky Performance Status in an HIV-infected sample [letter]: AIDS. 1991 Nov;5(11):1396-7. Unique Identifier : AIDSLINE MED/92118279; O'Dell MW; Riggs RV; Turner JL; Crawford A; Abrams C
Statistical approaches to evaluating prognostic indices in HIV infection. The Transfusion Safety Study Group [letter]: AIDS. 1991 Nov;5(11):1398. Unique Identifier : AIDSLINE MED/92118280; Buckley JD; Pike MC; Mosley JW
[Changes in the small cerebral vessels in the acquired immunodeficiency syndrome]: Neurologia. 1991 Aug-Sep;6(7):238-41. Unique Identifier : AIDSLINE MED/92118407; Ferrer X; Aguilar M; Arbizu T; Podzamcer D; Bolao F; Martos A; Peres Serra J; Servicio de Neurologia, Universitat de Barcelona.; In the necropsy exam of the brains of 13 patients with acquired immune deficiency syndrome (AIDS) cerebrovascular lesions were seen in 5 cases, three of them having AIDS encephalopathy. Hyalinosis was noted in 3 cases, and endarteritis obliterans and fibrinoid necrosis in one case each; both of them had associated per
HTLV-I infection in high-risk groups in Vizcaya, northern Spain [letter]: AIDS Res Hum Retroviruses. 1991 Jul;7(7):569-70. Unique Identifier : AIDSLINE MED/92118452; Esparza B; Santamaria JM; Miguel F; Saenz de Ugarte JR; Aizpiri J; Merino F
Direct binding of complement component C1q to human immunodeficiency virus (HIV) and human T lymphotrophic virus-I (HTLV-I) coinfected cells.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):579-85. Unique Identifier : AIDSLINE MED/92118454; Spear GT; Jiang HX; Sullivan BL; Gewurz H; Landay AL; Lint TF; Department of Immunology/Microbiology, Rush-Presbyterian-St.; Luke's Medical Center, Chicago, IL 60612.; Previous studies have shown that coinfection of the human T lymphotrophic virus type I (HTLV-I) chronically infected cell line MT4 with human immunodeficiency virus type 1 (HIV-1) results in cells which spontaneously activate complement via the classical pathway. This complement activation was antibody independent, ye
Alteration of HIV-1 infectivity and neutralization by a single amino acid replacement in the V3 loop domain.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):595-603. Unique Identifier : AIDSLINE MED/92118456; Ivanoff LA; Looney DJ; McDanal C; Morris JF; Wong-Staal F; Langlois AJ; Petteway SR Jr; Matthews TJ; Department of Antiinfectives, SmithKline Beecham Pharmaceuticals,; King of Prussia, PA 19406-0939.; The V3 loop (residues 303-338) of the human immunodeficiency virus type 1 (HIV-1) gp120 envelope protein represents a principal neutralizing determinant for the virus. An HIV-1 proviral clone containing a mutation in the V3 loop was constructed in which the proline residue at position 313 was changed to an alanine (P3
Sequence analysis of the V3 loop regions of the env genes of Ugandan human immunodeficiency proviruses.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):605-14. Unique Identifier : AIDSLINE MED/92118457; Oram JD; Downing RG; Roff M; Serwankambo N; Clegg JC; Featherstone AS; Booth JC; Division of Pathology, Centre for Applied Microbiology and; Research, Salisbury, Wiltshire, England.; Ugandan strains of human immunodeficiency virus type 1 (HIV-1) were isolated by cocultivation of peripheral blood lymphocytes from infected individuals with cord blood lymphocytes. Sequences from the V3 region of the env gene were amplified by the polymerase chain reaction (PCR) from chromosomal DNA obtained from low
Neutralizing antibodies against HIV-1 BRU and SF2 isolates generated in mice immunized with recombinant vaccinia virus expressing HIV-1 (BRU) envelope glycoproteins and boosted with homologous gp160.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):615-20. Unique Identifier : AIDSLINE MED/92118458; Hu SL; Klaniecki J; Dykers T; Sridhar P; Travis BM; Bristol-Myers Squibb Pharmaceutical Research Institute, Seattle,; WA.; Anti-human immunodeficiency virus type 1 (Anti-HIV-1) antibody response was compared in four groups of mice following inoculation with HIV-1 gp160, with live recombinant vaccinia virus expressing HIV-1 envelope glycoproteins, or with both immunogens in alternate orders for primary or secondary immunizations. Both subu
Cross-neutralizing antibodies to HIV-1 in mice after immunization with gp160 iscoms. Dissection of the immune response.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):621-7. Unique Identifier : AIDSLINE MED/92118459; Akerblom L; Nara P; Dunlop N; Morein B; Department of Veterinary Microbiology, Section of Virology,; Uppsala, Sweden.; Gp160 expressed in vaccinia and produced in vero cells was integrated into iscoms. Gp160 iscoms elicited a high serum antibody response in mice, and after two immunizations a ceiling was reached. The serum antibody response was dissected by the use of defined recombinant DNA products, representing different regions of
Event-related potentials in HIV-infected outpatients.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):629-35. Unique Identifier : AIDSLINE MED/92118460; Grotemeyer KH; Husstedt IW; Brundermann H; Busch H; Schlake HP; Zidek W; Department of Neurology, University of Munster, Federal Republic; of Germany.; Event-related potentials (ERP) were determined in 138 human immunodeficiency virus (HIV)-infected outpatients and 92 healthy controls of a corresponding age. Of the HIV-infected patients, 31.8% showed an abnormal latency of the P3-component of ERPs (P3-ERP), exceeding the mean value + 2 SD of P3-ERP latencies from age
[Kaposi's sarcoma located in the upper digestive tract. Apropos a case]: Rev Esp Enferm Dig. 1991 Nov;80(5):331-4. Unique Identifier : AIDSLINE MED/92118468; Romaguera Monzonis A; Osorio Guillon A; Alcobendas Rudilla F; Sarro Palau M; Vilar Puig L; Servicio de Cirugia General, Hospital de Bellvitge Princeps; D'Espanya.; A case of rectal and gastric location of Kaposi s sarcoma is reported. Although the typical location is cutaneous, gastrointestinal involvement of Kaposi s sarcoma is not an uncommon finding. Usually, it is detected when endoscopic, radiologic and autopsy studies are performed in patients with previous AIDS diagnosis.
'HIV transmission via blood and saliva splashes to the face' [letter; comment] [see comments]: Br Dent J. 1991 Dec 7-21;171(11-12):352. Unique Identifier : AIDSLINE MED/92118512; Emrey C
AIDS and the dental environment [letter]: Br Dent J. 1991 Dec 7-21;171(11-12):352. Unique Identifier : AIDSLINE MED/92118513; Hale WJ
Epithelioid angiomatosis affecting the oral cavity as a first sign of HIV infection.: Br Dent J. 1991 Dec 7-21;171(11-12):367-70. Unique Identifier : AIDSLINE MED/92118521; Speight PM; Zakrzewska J; Fletcher CD; Joint Department of Oral Pathology, London Hospital Medical; College.; Oral lesions are frequently the first manifestation of HIV infection and accurate diagnosis may be important in determining the management of individual patients. Lesions may be relatively common but non-specific, such as candidosis, or may be indicative of AIDS, such as Kaposi s sarcoma. Epithelioid angiomatosis is a
IgA nephropathy in a child with human immunodeficiency virus type 1 infection.: Pediatr Nephrol. 1991 Nov;5(6):724-6. Unique Identifier : AIDSLINE MED/92118626; Trachtman H; Gauthier B; Vinograd A; Valderrama E; Department of Pediatrics, Schneider Children's Hospital, New Hyde; Park, New York 11042.; Infection with the human immunodeficiency virus type 1 (HIV-1) can cause a spectrum of renal disease, termed acquired immunodeficiency syndrome (AIDS) nephropathy. The most common clinical manifestations of kidney involvement in HIV-1-infected patients are proteinuria and/or nephrotic syndrome, and the histopathologic
DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs.: New Biol. 1991 Oct;3(10):969-76. Unique Identifier : AIDSLINE MED/92118717; Bednarik DP; Duckett C; Kim SU; Perez VL; Griffis K; Guenthner PC; Folks TM; Centers for Disease Control, Division of Viral and Rickettsial; Diseases, Atlanta, GA 30333.; The regulation of cellular or viral gene expression is directly influenced by the pattern of methylated cytosine residues localized in the DNA of enhancer/promoter sequences. The mechanism of transcriptional silencing has been explained on the basis of either an indirect model, in which densely methylated DNA is recog
Tax responsiveness of the GM-CSF promoter is mediated by mitogen-inducible sequences other than kappa B.: New Biol. 1991 Oct;3(10):997-1004. Unique Identifier : AIDSLINE MED/92118720; Nimer S; Department of Medicine, UCLA School of Medicine 90024-1678.; The mechanism by which the human T-cell leukemia viruses type I and II (HTLV-I and -II) transform T cells is unknown, but the nonstructural Tax protein that these viruses produce is known to be essential for viral replication and to have the capacity to trans-activate cellular gene expression. The HTLV-I and -II Tax p
Metastatic calcification due to hypercalcemia in adult T-cell leukemia-lymphoma (ATLL).: Zentralbl Pathol. 1991;137(4):341-5. Unique Identifier : AIDSLINE MED/92118769; Senba M; Kawai K; Department of Pathology, Nagasaki University, Japan.; Four cases of metastatic calcification due to hypercalcemia in adult T-cell leukemia-lymphoma (ATLL) are reported. Serum calcium was at high levels, 15.4-19.4 mg/dl (normal range 8.4-10.4 mg/dl). In our cases, metastatic calcification was detected by v. Kossa s silver nitrate method for calcium in tubules of kidneys (
A human immunodeficiency virus peer education program for adolescent females.: J Adolesc Health. 1991 Sep;12(6):434-42. Unique Identifier : AIDSLINE MED/92118911; Slap GB; Plotkin SL; Khalid N; Michelman DF; Forke CM; Department of Pediatrics, Children's Hospital of Philadelphia, PA; 19104.; Black adolescent females living in urban environments are at high risk for human immunodeficiency virus (HIV) infection. Our objectives were to develop an HIV peer education program and to pilot-test its effect on knowledge and sexual behavior. Between September 1989 and March 1990, all females aged 12-19 years attend
[Epidemiological study of prisoners at risk for AIDS in a Spanish prison]: An Med Interna. 1991 Aug;8(8):382-6. Unique Identifier : AIDSLINE MED/92119024; Carbajal CL; Vallina E; Arribas JM; Diaz J; Dominguez B; Departamento de Medicina, Facultad de Medicina, Hospital; Universitario Covadonga, Oviedo.; Different proportions of the several AIDS risk practices in a Spanish prison during 1988 were studied. Also a epidemiologic study of the infectious diseases of the prisoners with some risk of this type was carried out. Of 135 prisoners with risk of AIDS, it was found that 91.2% of them were drug addicts. The index of
[Austrian's syndrome and infection with human immunodeficiency virus]: An Med Interna. 1991 Aug;8(8):391-2. Unique Identifier : AIDSLINE MED/92119026; Carrasco R; Roig P; Salavert M; Nieto A; Bernacer B; Rodriguez M; Navarro V; Seccion de Enfermedades Infecciosas, Hospital General; Universitario, Valencia.; A case of a patient diagnosed of Austrian syndrome associated to HIV infection is presented. Our aim is to highlight the frequent but not enough described association to pneumonia, endocarditis and meningitis caused by Streptococcus pneumonia to increased its knowledge and permit a correct and early treatment, improv
[HIV infection and tuberculosis]: An Med Interna. 1991 Aug;8(8):401-10. Unique Identifier : AIDSLINE MED/92119030; Carcaba V; Carton JA; Unidad de Infecciones, Hospital Valle del Nalon, Langreo,; Asturias.
Intracerebral haemorrhage due to acquired factor XIII inhibitor--successful response to factor XIII concentrate.: Blood Coagul Fibrinolysis. 1991 Aug;2(4):507-14. Unique Identifier : AIDSLINE MED/92119058; Daly HM; Carson PJ; Smith JK; Department of Haematology, Royal Cornwall Hospital (Treliske),; Truro, UK.; A 63-year-old woman presented with extensive bruising. An inhibitor to factor XIII was detected. Subsequent subcutaneous bruising and soft tissue haemorrhage into the left foot were treated with infusions of pasteurized factor XIII concentrate with good effect. Immunosuppression with cyclophosphamide was attempted but
Injection drug use and risk of HIV [letter; comment]: Can J Public Health. 1991 Sep-Oct;82(5):357. Unique Identifier : AIDSLINE MED/92119587; Farkas CS
Recent advances in the diagnosis and treatment of infectious diseases.: Compr Ther. 1991 Sep;17(9):3-5. Unique Identifier : AIDSLINE MED/92119922; White A; Department of Medicine, Indiana University School of Medicine,; Indianapolis.
HIV infection in the elderly.: Compr Ther. 1991 Sep;17(9):39-42. Unique Identifier : AIDSLINE MED/92119925; Boudes P; Department of Research and Teaching in Immunology, Faculty of; Medicine, Creteil, France.
Pneumocystis carinii in FNA of the thyroid.: Diagn Cytopathol. 1991;7(6):615-7. Unique Identifier : AIDSLINE MED/92120047; Walts AE; Pitchon HE; Department of Pathology, Cedars-Sinai Medical Center, Los; Angeles, CA 90048.; We report the diagnosis of Pneumocystis carinii (PC) in a fine-needle aspirate (FNA) from the thyroid of a human immunodeficiency virus infected (HIV+) male receiving aerosolized pentamidine as prophylaxis for Pneumocystis carinii pneumonia (PCP). The clinical diagnosis prior to FNA was multinodular goiter. The patien
[Pancreatitis, hypocalcemia and myositis associated with primary HIV infection (letter)]: Gastroenterol Clin Biol. 1991;15(11):860. Unique Identifier : AIDSLINE MED/92120353; Combes R; Amouyal G; Rene E
AIDS, older people, and social work.: Health Soc Work. 1991 Nov;16(4):237-44. Unique Identifier : AIDSLINE MED/92120598; Gutheil IA; Chichin ER; Graduate School of Social Service, Fordham University, New York,; NY 10023.; The acquired immune deficiency syndrome (AIDS) epidemic is significantly affecting older people. Older people themselves may be HIV positive, or they may be the caregiving spouse, partner, parent, or grandparent of a person with AIDS. In addition, older people may share housing or institutional space with people with
[HIV pneumonia: a change in attitude? Cotrimoxazole is favored for prevention]: Fortschr Med. 1991 Nov 10;109(32):78. Unique Identifier : AIDSLINE MED/92120617; Mahler W; Redaktionsburo Urban & Vogel, Berlin.
[I don't see medical reasons for a change. Dr. H. Busch, Munster, takes a position on prevention of pneumocystis carinii pneumonia with pentamidine aerosol (interview by Wilma Mahler)]: Fortschr Med. 1991 Nov 20;109(33):94, 97. Unique Identifier : AIDSLINE MED/92120626; Busch H
Primary proliferative and cytotoxic T-cell responses to HIV induced in vitro by human dendritic cells.: Immunology. 1991 Nov;74(3):399-406. Unique Identifier : AIDSLINE MED/92120708; Macatonia SE; Patterson S; Knight SC; Antigen Presentation Research Group, MRC Clinical Research; Centre, Harrow, Middlesex.; In earlier studies, primary proliferative and cytotoxic T-cell (CTL) responses to influenza virus were produced in vitro by using mouse dendritic cells (DC) pulsed with virus or viral peptide as the stimulus for syngeneic T cells in 20-microliters hanging-drop cultures. We have now adapted this system for producing pr
Murine immune response to HIV-1 p24 core protein following subcutaneous, intraperitoneal and intravenous immunization.: Immunology. 1991 Nov;74(3):467-72. Unique Identifier : AIDSLINE MED/92120718; Fyfe L; Maingay J; Robinson AC; Howie SE; Department of Pathology, University of Edinburgh Medical School.; The murine immune response to baculovirus-produced human immunodeficiency virus type-1 (HIV-1)p24 was examined after injection by three different routes: subcutaneously (s.c.), intraperitoneally (i.p.) and intravenously (i.v.). Both antigen-specific T-cell proliferation and serum antibody were induced by i.p. injectio
Dendritic cells and dinitrochlorobenzene (DNCB): a new treatment approach to AIDS [published erratum appears in Immunol Lett 1992 Aug;33(3):316]: Immunol Lett. 1991 Aug;29(3):191-6. Unique Identifier : AIDSLINE MED/92120736; Stricker RB; Elswood BF; Children's Hospital of San Francisco, CA 94118.; Recent studies suggest that antigen-presenting cells (dendritic cells) may play a key role in the pathogenesis of human immunodeficiency virus (HIV) infection. This observation makes new immunomodulatory treatment strategies desirable. Topical dinitrochlorobenzene (DNCB) is discussed as a possible treatment modality i
Ethics and equity in U.S. health care: the data.: Int J Health Serv. 1991;21(4):637-51. Unique Identifier : AIDSLINE MED/92120808; Rice DP; Department of Social and Behavioral Sciences, University of; California, San Francisco 94143.; Access to and equality in health care has deteriorated in the 1980s, as shown by the data on racial differences in reducing infant mortality rates, in life expectancy, and in the incidence and economic burden of AIDS. Various health status measures indicate significant declines with decreasing income, and the use of m
[Detection of proviral HIV DNA with polymerase chain reaction in the epidermis]: Hautarzt. 1991 Nov;42(11):704-6. Unique Identifier : AIDSLINE MED/92120903; Naher H; Schule T; Hartmann M; Petzoldt D; Hautklinik, Ruprecht-Karls-Universitat Heidelberg.; The infection of cells of the epidermis with HIV can still not be taken as proved, since the demonstration of HIV in Langerhans cells has not been universally accepted. In our study, the polymerase chain reaction was used to look for proviral HIV-DNA in epidermal cells collected by the suction blister technique. The p
The role of the fibroblast in Dupuytren's contracture.: Hand Clin. 1991 Nov;7(4):669-80; discussion 681. Unique Identifier : AIDSLINE MED/92121230; Murrell GA; Division of Orthopedic Surgery, Duke University Medical Center,; Durham, North Carolina.; Ultrastructural, immunohistochemical, and biochemical studies to date show that the fibroblast in Dupuytren s contracture is identical to palmar fascia fibroblasts in patients unaffected by Dupuytren s contracture, and to all other fibroblasts. The major difference relating to fibroblasts is that in Dupuytren s contra
[Induction and analysis of viral specific cytotoxic T lymphocytes with modern biotechnology]: Nippon Ika Daigaku Zasshi. 1991 Dec;58(6):703-7. Unique Identifier : AIDSLINE MED/92121375; Takahashi H; Department of Microbiology and Immunology, Nippon Medical School.
Chronic pancreatitis and biliary fibrosis associated with cryptosporidiosis in simian AIDS.: J Comp Pathol. 1991 Nov;105(4):415-21. Unique Identifier : AIDSLINE MED/92121505; Baskerville A; Ramsay AD; Millward-Sadler GH; Cook RW; Cranage MP; Greenaway PJ; Public Health Laboratory Service, Centre for Applied Microbiology; and Research, Salisbury, Wiltshire, U.K.; Two Rhesus monkeys infected with simian immunodeficiency virus for 15 and 24 months developed generalized oedema and one became jaundiced. At necropsy, the liver and pancreas were hard and irregular and the gall bladder was thickened. Histopathological examination showed extensive fibrosis of the pancreas, loss of exo
Clinical applications of human granulocyte-macrophage colony-stimulating factor.: Int J Cell Cloning. 1991 Nov;9(6):531-41. Unique Identifier : AIDSLINE MED/92121666; Sakamoto KM; Gasson JC; Department of Pediatrics, UCLA School of Medicine 90024-1752.; Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor that stimulates myeloid cell proliferation and maturation and enhances the function of terminally differentiated effector cells. Phase I and II clinical trials have demonstrated mild to moderate toxicities at doses of less than
Primary intraosseous AIDS-associated Kaposi's sarcoma. Report of two cases with initial jaw involvement.: Int J Oral Maxillofac Surg. 1991 Dec;20(6):366-8. Unique Identifier : AIDSLINE MED/92121684; Langford A; Pohle HD; Reichart P; Abteilung fur zahnarztliche/Oralchirurgie Nord, Freie; Universitat, Berlin, Germany.; AIDS-associated Kaposi s sarcoma (KS), which in 80% of cases occurs in the oral cavity, usually presents with characteristic clinical features such as brown-bluish pigmented macules or tumorous lesions. In later stages the tumor, most probably originating from the vascular endothelium, may secondarily induce erosion o
Periodontal status of HIV-seropositive and AIDS patients.: J Periodontol. 1991 Oct;62(10):623-7. Unique Identifier : AIDSLINE MED/92122080; Friedman RB; Gunsolley J; Gentry A; Dinius A; Kaplowitz L; Settle J; Department of Oral and Maxillofacial Surgery, MCV/VCU School of; Dentistry, Richmond.; Few reported studies have evaluated the periodontal status of individuals infected by human immunodeficiency virus (HIV). The majority of these reports have evaluated the periodontal status of individuals presenting to dental care facilities due to oral problems. These reports suggest that severe gingival inflammation
Hematopoietic growth factors allowing aggressive treatment [news]: J Natl Cancer Inst. 1991 Dec 4;83(23):1710-1. Unique Identifier : AIDSLINE MED/92122314; Ismach J
Clinical features of human immunodeficiency virus associated nephropathy.: Kidney Int Suppl. 1991 Dec;35:S13-8. Unique Identifier : AIDSLINE MED/92122631; Rao TK; SUNY Health Science Center, Brooklyn.
The nephropathology in human immunodeficiency virus (HIV-1) infection.: Kidney Int Suppl. 1991 Dec;35:S19-23. Unique Identifier : AIDSLINE MED/92122632; Bourgoignie JJ; Pardo V; Department of Medicine, University of Miami School of Medicine,; Florida.; The nephropathology observed in patients with HIV infection is reviewed. A characteristic, though not specific, nephropathy associated with HIV infection can be encountered in HIV carriers, in patients with AIDS-related complex and in patients with AIDS. HIV-associated nephropathy typically exhibits the features of an
Gram-negative bacterial pneumonia with secondary aspergillosis in an AIDS patient.: Klin Wochenschr. 1991 Nov 15;69(18):853-6. Unique Identifier : AIDSLINE MED/92122694; Bonatz K; Weiss A; Hehlmann R; Assmus HP; Heine M; III. Medizinische Klinik, Fakultat fur Klinische Medizin; Mannheim, Universitat Heidelberg.; A 40-year-old, HIV-infected female patient received antibiotic treatment for a urinary tract infection. After the initial success of therapy and a symptom-free period, she developed pneumonia with septic shock and adult respiratory distress syndrome (ARDS). In spite of intensive care and respirator therapy with positi
GSH rescue by N-acetylcysteine.: Klin Wochenschr. 1991 Nov 15;69(18):857-62. Unique Identifier : AIDSLINE MED/92122695; Ruffmann R; Wendel A; Inpharzam SA, Cadempino, Schweiz.; Reduced glutathione (GSH) is the main intracellular low molecular weight thiol. GSH acts as a nucleophilic scavenger and as an enzyme-catalyzed antioxidant in the event of electrophilic/oxidative tissue injury. Therefore, GSH has a major role as a protector of biological structures and functions. GSH depletion has bee
Automated severity classification of AIDS hospitalizations.: Med Decis Making. 1991 Oct-Dec;11(4 Suppl):S41-5. Unique Identifier : AIDSLINE MED/92122948; Stitt FW; Lu Y; Dickinson GM; Klimas NG; Department of Epidemiology and Public Health, University of; Miami, School of Medicine, Florida 33101.; To validate an automated AIDS severity-of-illness prognostic algorithm, 2,113 discharge summaries of HIV-infected patients were merged with the Problem-Oriented Medical Synopsis (POMS) and an HIV risk registry. The combination of a medically derived classification and staging algorithm with multivariate statistical te
[HIV-associated non-hodgkin lymphoma. Prognosis and therapeutic options]: Med Klin. 1991 Dec 15;86(12):646-54, 660. Unique Identifier : AIDSLINE MED/92123031; Schrappe M; Pohl C; Tesch H; Diehl V; Medizinische Klinik I der Universitat zu Koln.
Tuberculosis morbidity in the United States: final data, 1990.: MMWR CDC Surveill Summ. 1991 Dec;40(3):23-7. Unique Identifier : AIDSLINE MED/92123063; Jereb JA; Kelly GD; Dooley SW Jr; Cauthen GM; Snider DE Jr; The number of tuberculosis cases reported to CDC has been increasing since 1988, after a long historic decline. In 1990, 25,701 cases were reported, an increase of 9.4% over the 1989 figure and the largest annual increase since 1953. From 1985 to 1990, reported cases increased by 15.8%. Disproportionately greater incr
[Rehabilitative measures in hearing-impaired children]: Monatsschr Kinderheilkd. 1991 Dec;139(12):803-7. Unique Identifier : AIDSLINE MED/92123232; von Wedel H; von Wedel UC; Zorowka P; Hals-Nasen-Ohren-Klinik der Universitat Koln.; On the basis of certain fundamental data on the maturation processes of the central auditory pathways in early childhood the importance of early intervention with hearing aids is discussed and emphasized. Pathological hearing, that is acoustical deprivation in early childhood will influence the maturation process. Ver
[AIDS in Italy (news)]: Minerva Chir. 1991 Oct 15;46(19):1074-5. Unique Identifier : AIDSLINE MED/92123490
[AIDS in the world (news)]: Minerva Chir. 1991 Oct 15;46(19):1075-6. Unique Identifier : AIDSLINE MED/92123491; Di Nola F
Is malabsorption an important cause of growth failure in HIV-infected children?: Nutr Rev. 1991 Nov;49(11):341-3. Unique Identifier : AIDSLINE MED/92123520; Sixty percent of HIV-infected children malabsorbed carbohydrate (lactose or D-xylose). Surprisingly, however, carbohydrate malabsorption was not predictive of growth failure. Although HIV infection, in the absence of detectable enteric infection, may result in small intestinal injury, additional factors may also be re
HIV infection among members of the Army Reserve components residing in New York City.: N Y State J Med. 1991 Nov;91(11):479-82. Unique Identifier : AIDSLINE MED/92123527; Cowan DN; Brundage JF; Pomerantz RS; Gardner LI; Miller RN; Wann ZF; SRA Technologies, Inc. Alexandria VA 22302.; A total of 10,722 members of the US Army Reserve and Army National Guard residing within the five boroughs of New York City (NYC) were tested for antibody to human immunodeficiency virus (HIV). The crude prevalence in NYC was found to be 10.6 per 1,000, compared with a national prevalence of 1.6 per 1,000. The highest
Face to face with AIDS [see comments]: N Y State Dent J. 1991 Dec;57(10):11-3. Unique Identifier : AIDSLINE MED/92123550; Giambalvo AM
[Insurance and AIDS (news)]: Rev Infirm. 1991 Nov 28;41(18):4. Unique Identifier : AIDSLINE MED/92124072
[Surgical gloves (news)]: Rev Infirm. 1991 Nov 28;41(18):8-9. Unique Identifier : AIDSLINE MED/92124075
[75% of seropositives are heterosexual (news)]: Rev Infirm. 1991 Dec 12;41(19):4. Unique Identifier : AIDSLINE MED/92124085
[Neuropsychiatric complications of AIDS]: Rev Infirm. 1991 Dec 12;41(19):43-6. Unique Identifier : AIDSLINE MED/92124086; Lamy C
[AIDS, hepatitis: waiting for a decree (news)]: Rev Infirm. 1991 Dec 12;41(19):6. Unique Identifier : AIDSLINE MED/92124091
[Chemotherapy of HIV]: Rev Infirm. 1991 Dec 27;41(20):44-8. Unique Identifier : AIDSLINE MED/92124101; Belec L; Bledin M
The prevention of HIV infection from injecting drug use--a review of health promotion approaches.: Soc Sci Med. 1991;33(9):977-83. Unique Identifier : AIDSLINE MED/92124203; Nutbeam D; Blakey V; Pates R; Department of Public Health, University of Sydney, NSW,; Australia.; This review examines the prevention of HIV infection among injecting drug users through the framework provided by the Ottawa Charter on Health Promotion. Among the key issues considered are the problems of achieving the changes in policy and service direction needed to prevent HIV infection. The role of the media in i
Notification of the sex and needle-sharing partners of individuals with human immunodeficiency virus in rural South Carolina: 30-month experience.: Sex Transm Dis. 1991 Oct-Dec;18(4):217-22. Unique Identifier : AIDSLINE MED/92124263; Wykoff RF; Jones JL; Longshore ST; Hollis SL; Quiller CB; Dowda H; Gamble WB; South Carolina Department of Health and Environmental Control; (SCDHEC).; The authors conducted a confidential and voluntary partner notification program to identify and educate the sex and needle-sharing partners of individuals with the human immunodeficiency virus (HIV) in a rural health district in South Carolina. During the first 30 months, of 485 named contacts, 290 (60%) were resident
A voluntary serosurvey and behavioral risk assessment for human immunodeficiency virus infection among college students.: Sex Transm Dis. 1991 Oct-Dec;18(4):223-7. Unique Identifier : AIDSLINE MED/92124264; Kotloff KL; Tacket CO; Wasserman SS; Bridwell MW; Cowan JE; Clemens JD; Brothers TA; O'Donnell SA; Quinn TC; Department of Pediatrics and Geographic Medicine, University of; Maryland School of Medicine, Baltimore 21201.; The authors conducted a voluntary serosurvey and educational campaign among 3394 undergraduate students attending the University of Maryland at College Park to determine the prevalence of and risk factors for human immunodeficiency virus type 1 (HIV-1) infection. Two students were seropositive (0.06%, 95% confidence i
A possible association between HLA and HTLV-I-associated myelopathy (HAM) in Japanese.: Tissue Antigens. 1991 May;37(5):230-1. Unique Identifier : AIDSLINE MED/92124457; Nishimura Y; Okubo R; Minato S; Itoyama Y; Goto I; Mori M; Hirayama K; Sasazuki T; Department of Genetics, Medical Institute of Bioregulation,; Fukuoka, Japan.
AIDS protection is patients' right [news]: Todays OR Nurse. 1991 Nov;13(11):39. Unique Identifier : AIDSLINE MED/92124508
Mechanisms behind heterosexual HIV transmission explored [news]: Todays OR Nurse. 1991 Nov;13(11):41-2. Unique Identifier : AIDSLINE MED/92124510
Toxin targets AIDS-infected cells [news]: Todays OR Nurse. 1991 Dec;13(12):39. Unique Identifier : AIDSLINE MED/92124518
Diagnostic value of ascites gamma interferon levels in tuberculous peritonitis. Comparison with adenosine deaminase activity.: Tubercle. 1991 Sep;72(3):193-7. Unique Identifier : AIDSLINE MED/92124591; Ribera E; Martinez Vasquez JM; Ocana I; Ruiz I; Jiminez JG; Encabo G; Segura RM; Pascual C; Department of Internal Medicine, Vall d'Hebron General Hospital,; Autonomous University of Barcelona, Spain.; The value of ascites gamma interferon concentration and ascites adenosine deaminase activity in distinguishing tuberculosis from other causes of ascites was examined in a prospective study of 86 patients with ascites, including 16 with tuberculous peritonitis. Gamma interferon concentration was higher in tuberculous p
Lentivirus-induced pulmonary lesions in rhesus monkeys (Macaca mulatta) infected with simian immunodeficiency virus.: Vet Pathol. 1991 Nov;28(6):506-13. Unique Identifier : AIDSLINE MED/92124666; Baskin GB; Murphey-Corb M; Martin LN; Soike KF; Hu FS; Kuebler D; Department of Pathology, Tulane University, Covington, LA.; Necropsy reports from 28 rhesus monkeys that had been experimentally infected with simian immunodeficiency virus (SIV) and that were free of cytomegalovirus were reviewed. Lung sections from 24 of these monkeys that had no etiologic agent other than SIV detected in the lung were st
[HIV infection in children]: Vrach Delo. 1991 Jul;(7):11-7. Unique Identifier : AIDSLINE MED/92124827; Dmitriev VI
Cardiac dysfunction in patients seropositive for the human immunodeficiency virus.: West J Med. 1991 Oct;155(4):373-9. Unique Identifier : AIDSLINE MED/92124888; Johnson JE; Slife DM; Anders GT; Bailey SR; Blanton HM; McAllister CK; Latham RD; Pulmonary Disease/Critical Care Service, Brooke Army Medical; Center, Fort Sam Houston, Texas 78234-6200.; To confirm the presence of cardiac dysfunction in a group of patients seropositive for the human immunodeficiency virus with either dyspnea on exertion or a reduced anaerobic threshold, 9 patients with no history of opportunistic infection underwent exercise right-sided heart catheterization. When compared with 13 con
Patterns of primary care of patients infected with human immunodeficiency virus.: West J Med. 1991 Oct;155(4):380-3. Unique Identifier : AIDSLINE MED/92124889; Wenrich MD; Ramsey PG; Department of Medicine, University of Washington School of; Medicine, Seattle 98195.; To determine the patterns of care of patients infected with the human immunodeficiency virus (HIV), data from 2 sources were analyzed. Initial data obtained from the Washington State HIV/Acquired Immunodeficiency Syndrome (AIDS) Epidemiology Unit indicate that 46% of patients with class IV AIDS were seen by physicians
[AIDS and the law. Does the state neglect its protective function?]: Diskussionsforum Med Ethik. 1991 Sep;(9):LIII-LV. Unique Identifier : AIDSLINE MED/92124934; von Brauchitsch I; Criminal law and labor legislation concerning with AIDS and the problems of data-protection in both countries are shown.
Cryptosporidiosis of the appendix vermiformis: a case report.: Z Gastroenterol. 1991 Nov;29(11):606-8. Unique Identifier : AIDSLINE MED/92124958; Oberhuber G; Lauer E; Stolte M; Borchard F; Institut fur Pathologie, Klinikum Bayreuth, Bundesrepublik; Deutschland.; The present case report describes a 30-year-old man with AIDS who developed cryptosporidiosis of the appendix vermiformis. The patient had been admitted to hospital with all the symptoms of appendicitis, and an appendectomy was performed. The histological work-up of the surgical specimen revealed an acute phlegmonous
Comparative specificity and sensitivity evaluation of a rapid test for the detection of anti HIV antibodies (Test Pack).: Allergol Immunopathol (Madr). 1991 Mar-Apr;19(2):85-7. Unique Identifier : AIDSLINE MED/92125251; d'Offizi G; Papetti C; Valdarchi C; Pinter E; Rainaldi L; Pontesilli O; Ferrara R; Aiuti F; Cattedra di Allergologia ed Immunologia Clinica, Universita di; Roma, La Sapienza, Italy.
Case report: disseminated Mycobacterium gordonae infection in a nonimmunocompromised host.: Am J Med Sci. 1991 Dec;302(6):382-4. Unique Identifier : AIDSLINE MED/92125319; Jarikre LN; Tuberculosis Treatment Unit, Hamad Medical Corporation, Rumailah; Hospital, Doha, State of Qatar, Arabian Gulf.; Mycobacterium gordonae is considered the least pathogenic of the Runyon Group II mycobacteria, although there are now well-documented reports of infection varying from localized soft tissue infection to disseminated life threatening diseases. We report a 40-year-old Pakistani housewife, treated in childhood for tuberc
Homeless youths and HIV infection.: Am Psychol. 1991 Nov;46(11):1188-97. Unique Identifier : AIDSLINE MED/92125661; Rotheram-Borus MJ; Koopman C; Ehrhardt AA; Division of Child Psychiatry, Columbia University, New York, NY; 10032.; Risk of human immunodeficiency virus (HIV) infection exacerbates the already difficult lives of 1.5 million homeless adolescents in the United States . Homeless youths engage in sexual and substance-abuse behaviors that place them at increased risk of contracting HIV, and they demonstra
New vaccines for the prevention and treatment of disease.: Ann Med Interne (Paris). 1991;142(6):429-33. Unique Identifier : AIDSLINE MED/92125719; Morrow WJ; Kohler H; IDEC Pharmaceuticals Corporation, La Jolla, California 92037.
[Zidovudine (AZT). Current state of the development]: Ann Med Interne (Paris). 1991;142(6):444-55. Unique Identifier : AIDSLINE MED/92125722; Kouzan S; Nebout T; Laboratoires Wellcome SA, Paris.
[Abdominal aortic aneurysm caused by Salmonella enteridis in a patient with human immunodeficiency virus (letter)]: Ann Med Interne (Paris). 1991;142(6):456-7. Unique Identifier : AIDSLINE MED/92125723; Roussin-Bretagne S; Robert M; Tricot JF; Pangon B; Harzic M; Doll J; Andrieu J
[A case of nocardiosis revealing acquired immunodeficiency syndrome (letter)]: Ann Med Interne (Paris). 1991;142(6):457-9. Unique Identifier : AIDSLINE MED/92125724; Balloul H; Perronne C; el Rassi R; Bouali I; Vachon F
[Kaposi's disease and HIV negative acquired immunodeficiency syndrome (AIDS) (letter)]: Ann Med Interne (Paris). 1991;142(6):459-61. Unique Identifier : AIDSLINE MED/92125725; Huart C; Heid E; Farque JF; Grosshans E
[Cardiac complications of pentamidine isethionate. Report of a case (letter)]: Ann Med Interne (Paris). 1991;142(6):461-2. Unique Identifier : AIDSLINE MED/92125726; Lortholary O; Caumes E; Valentin MA; Katlama C; Danis M; Gentilini M
AIDS, wound healing, and the surgeon's well-being [editorial]: Ann Plast Surg. 1991 Oct;27(4):297-8. Unique Identifier : AIDSLINE MED/92125755; Fisher JC; Gorney M
A unified hypothesis for three cardinal features of HIV immunology: authors' reply [letter; comment]: J Acquir Immune Defic Syndr. 1991;4(11):1165. Unique Identifier : AIDSLINE MED/92092183; Dalgleish AG; Habeshaw J; Manca F
Selenium status of HIV-1 infected individuals [letter; comment]: JPEN J Parenter Enteral Nutr. 1991 Nov-Dec;15(6):693-4. Unique Identifier : AIDSLINE MED/92114258; Mantero-Atienza E; Beach RS; Gavancho MC; Morgan R; Shor-Posner G; Fordyce-Baum MK
Treatment strategies for AIDS-related malignancies.: Oncology (Huntingt). 1991 Sep;5(9 Suppl):25-30. Unique Identifier : AIDSLINE MED/92088883; Triozzi PL; Division of Hematology and Oncology, Ohio State University.; We have made progress in the therapy of AIDS-related malignancies, although it is obvious that our treatment strategies, at present, are not--by any measure--satisfactory. Effective treatment should take into account the pathogenesis and etiology of the malignancy; immune and performance status of the patient; the rat
Generalised cutaneous rash associated with foscarnet usage in AIDS [letter; comment]: J Infect. 1991 Nov;23(3):336-7. Unique Identifier : AIDSLINE MED/92091844; Blanshard C
CD4 to CD8 ratio and in vitro lymphoproliferative responses during experimental gingivitis in pregnancy and post-partum.: J Periodontol. 1991 Nov;62(11):663-7. Unique Identifier : AIDSLINE MED/92092149; Raber-Durlacher JE; Zeijlemaker WP; Meinesz AA; Abraham-Inpijn L; Department of General Pathology and Internal Medicine, Academic; Center for Dentistry Amsterdam, The Netherlands.; The absolute numbers and percentages of peripheral T, B, and NK cells were assessed in 7 women, both during the second trimester of pregnancy and 6 months post-partum. Furthermore, the in vitro responses of peripheral blood lymphocytes (PBL) to several mitogens and a preparation of Prevotella intermedia were compared
[Usefulness of folinic acid in cytopenia induced by antiparasitic drugs in AIDS patients]: Presse Med. 1991 Oct 26;20(34):1677-81. Unique Identifier : AIDSLINE MED/92093881; Niyongabo T; Leport C; Vilde JL; Service des Maladies infectieuses et tropicales, Groupe; Hospitalier Bichat-Claude Bernard, Paris.; The scientific basis for using folinic acid in combination with the antiparasitic drugs prescribed to AIDS patients has been reviewed. In vitro and experimental data are unclear. On the basis of folinic acid metabolism and pharmacology and of clinical experience, we suggest that folinic acid should not be systematical
[Cutaneous and mucous hyperpigmentation in AIDS (letter)]: Presse Med. 1991 Oct 26;20(34):1686, 1690. Unique Identifier : AIDSLINE MED/92093891; Lacour JP; Gallais V; Bodokh I; Ghanem G; Ortonne JP
[Seroprevalence of HIV-1 virus in Zaire. Analysis of 1404 subjects]: Presse Med. 1991 Nov 2;20(35):1717-9. Unique Identifier : AIDSLINE MED/92093894; Welo K; Almaviva M; Maganga W; Mukengeshay K; Ceravolo C; Piccioni I; Furbatto A; Lupo A; Comite regional de lutte contre le SIDA, Goma, Zaire.; Between January and December 1989, 1,404 subjects (mean age 26 years) admitted or seen at the out-patient clinic of the hospital of Goma, Northern Kivu, were investigated for anti-HIV 1 antibodies by the ELISA and Western blot techniques. Seventy-eight out of 808 men (10 percent) and 127 out of 596 women (21 percent)
[Nephropathie associated with human immunodeficiency virus infection: possible therapeutic value of zidovudine (letter)]: Presse Med. 1991 Nov 9;20(36):1785-6. Unique Identifier : AIDSLINE MED/92093917; Michel C; Dosquet P; Viron B; Meyohas MC; Ronco P; Mignon F
Stimulatory and suppressive effects of infection of dendritic cells with HIV-1.: Immunol Lett. 1991 Oct;30(2):213-8. Unique Identifier : AIDSLINE MED/92098117; Knight SC; Patterson S; Macatonia SE; Antigen Presentation Research Group, Clinical Research Centre,; Harrow, Middlesex, U.K.; Two effects of HIV infection on human dendritic cells (DC) in vitro have been examined. The first was the stimulation of primary responses to HIV antigens in autologous lymphocytes from normal donors. When DC were exposed to HIV (10(4) TCID/10(5) cells) for up to 24 h before addition to autologous lymphocytes, a marke
Effect of thymic extract on allogeneic MLR and mitogen-induced responses in patients with chronic active hepatitis B.: Immunol Invest. 1991 Dec;20(7):545-55. Unique Identifier : AIDSLINE MED/92098126; Zeman K; Dworniak D; Tchorzewski H; Pokoca L; Majewska E; Department of Pathophysiology & Immunology, Military Medical; Academy, Lodz, Poland.; Cell-mediated immune reactions are involved in the development of chronic active hepatitis (CAH-B). The present studies confirm that lymphocyte from patients with CAH-B have a decreased allogeneic mixed lymphocyte reaction (allo-MLR) and mitogen-induced responses. These abnormalities probably play a role in the immuno
[The reasons for false positive results with recombinant preparations in HIV infection]: Zh Mikrobiol Epidemiol Immunobiol. 1991 Sep;(9):32-5. Unique Identifier : AIDSLINE MED/92101637; Karal'nik BV; Riazanova GL; Shuratov IKh; Enzyme immunoassay (EIA) with the use of test systems based on recombinant HIV antigens has yielded positive results much more often than that with the test systems based on HIV lysate. In comparison with the use of protein A-peroxidase conjugate, the use of antiglobulin conjugates decreased the specificity of EIA, th
Foscarnet effective in acyclovir-resistant herpes [news]: Am Pharm. 1991 Nov;NS31(11):12. Unique Identifier : AIDSLINE MED/92101886
Pyrimethamine-clarithromycin combination for therapy of acute Toxoplasma encephalitis in patients with AIDS.: Antimicrob Agents Chemother. 1991 Oct;35(10):2049-52. Unique Identifier : AIDSLINE MED/92102183; Fernandez-Martin J; Leport C; Morlat P; Meyohas MC; Chauvin JP; Vilde JL; Department of Infectious and Tropical Diseases, Bichat-Claude; Bernard Hospital, Paris, France.; Clarithromycin, a new macrolide, is effective in treating experimental Toxoplasma gondii infection. A pyrimethamine-clarithromycin combination was evaluated for the treatment of acute Toxoplasma encephalitis in 13 AIDS patients. The scheduled regimen was 2 g of clarithromycin per day and 75 mg of pyrimethamine per day
Prevention of hepatitis B in GI laboratories.: Gastroenterol Nurs. 1991 Dec;14(3):119-21. Unique Identifier : AIDSLINE MED/92103051; Sherman D
Expression of interleukin-2 receptor and HLA-DR on lymphocyte subsets of gingival crevicular fluid in patients with periodontitis.: J Periodontal Res. 1991 Nov;26(6):502-10. Unique Identifier : AIDSLINE MED/92106160; Takeuchi Y; Yoshie H; Hara K; Department of Periodontology, Niigata University School of; Dentistry, Japan.; Expression of interleukin-2 receptor (IL2R) and HLA-DR on lymphocytes of gingival crevicular fluid (GCF) was examined by two-color flow cytometric analysis. GCF from 15 patients with periodontitis was collected by crevicular washing. Mononuclear cells were isolated by Ficoll-paque gradient centrifugation from inflamed
[Adult T-cell leukemia with CD3 (-), CD4 (-) and CD8 (-)]: Rinsho Byori. 1991 Oct;39(10):1105-8. Unique Identifier : AIDSLINE MED/92106508; Ohta K; Ohira H; Nakao Y; Yasui Y; Tatsumi N; Okuda K; Department of Laboratory Medicine, Osaka City University Medical; School.; A case of an adult T-cell leukemia (ATL) with double negative (CD4-, CD8-) phenotype is reported. A-57-year-old man was consulted by his home doctor with us because of leucocytosis, splenomegaly and systemic lymphadenopathy. On admission, white blood cell count was 87,500/microliters with 77% of convoluted atypical ce
[Current status of HTLV1 infection. Human T cell Leukemia Virus type 1 (editorial]: Presse Med. 1991 Nov 23;20(39):1921-2. Unique Identifier : AIDSLINE MED/92107789; Vernant JC
[Pleurisy in HIV infected patients]: Presse Med. 1991 Nov 23;20(39):1931-4. Unique Identifier : AIDSLINE MED/92107792; Allier I; Cadranel J; Parquin F; Denis M; Lepen de Ven C; Antoine M; Mayaud C; Akoun G; Service de Pneumologie et de Reanimation respiratoire, Hopital; Tenon, Paris.; Thirty-seven records of pleural effusion of known cause which occurred in HIV-seropositive patients hospitalized at the Tenon hospital, Paris, between 1985 and 1990 were analyzed retrospectively and divided into two groups: group 1 (n = 21) made up of kaposian effusions, and group 2 (n = 16) of infectious effusions se
[Tuberculous splenic abscess in a patient with HIV seropositivity (letter)]: Presse Med. 1991 Nov 23;20(39):1946. Unique Identifier : AIDSLINE MED/92107797; De Marco O; Nasfi A; Bacques O; Gamerman H
[Monoclonal immunoglobulins in kidney transplantation. Characterisation, evolution and risk factors]: Presse Med. 1991 Nov 27;20(40):2033-5. Unique Identifier : AIDSLINE MED/92107830; Chakalarovski C; Lang P; Buisson C; Intrator L; Deforges L; Benmaadi A; Fruchaud G; Rostoker G; Bourgeon B; Remy P; et al; Service de Nephrologie, Hopital Henri-Mondor, Creteil.; Sera from 192 consecutive HIV negative renal transplant patients with more than 6 months follow-up were investigated for monoclonal or oligoclonal immunoglobulins (mIg) by immunoelectrophoresis or immunofixation. Gammapathy was present in 25 patients (13 percent). Eleven patients had only one monoclonal band, whereas
Second AIDS drug approved for those who can't tolerate AZT [news]: Oncology (Huntingt). 1991 Nov;5(11):103. Unique Identifier : AIDSLINE MED/92110137
Burroughs Wellcome AIDS-Patient Assistance Program announced [news]: Oncology (Huntingt). 1991 Nov;5(11):57. Unique Identifier : AIDSLINE MED/92110145
Oncology/AIDS grant received by Case Western Reserve University School of Nursing [news]: Oncology (Huntingt). 1991 Nov;5(11):57. Unique Identifier : AIDSLINE MED/92110146
[Experience in organizing a public showing of health bulletins on AIDS]: Feldsher Akush. 1991 Sep;56(9):40-2. Unique Identifier : AIDSLINE MED/92111820; Mozhaev VP
Maternal predictors of HIV vertical transmission.: Eur J Obstet Gynecol Reprod Biol. 1991 Nov 26;42(2):131-6. Unique Identifier : AIDSLINE MED/92111923; Monforte AA; Ravizza M; Muggiasca ML; Novati R; Musicco M; Zuccotti GV; Cavalli G; Principi N; Conti M; Pardi G; et al; Clinic of Infectious Diseases, Sacco Hospital, Milan, Italy.; We performed a retrospective study of 57 HIV-positive pregnant women and their children to look for maternal parameters related to rates of vertical transmission of HIV. Sixteen (28%) infants were HIV-infected. There was no positive correlation between maternal risk factors for HIV and vertical transmission of HIV. Mu
The 1990 Harry Bruce Legislative Fellowship.: J Dent Educ. 1991 Dec;55(12):802-9. Unique Identifier : AIDSLINE MED/92113153; Cameron CA; Department of Dental Public Health Sciences, School of Dentistry,; University of Washington, Seattle 98195.; The experiences described here recount my involvement in the various legislative processes and measure the tangible knowledge gained. It is most difficult to convey the impact of these experiences on my values and insights. This of course is not an uncommon phenomenon, it s encountered daily in dental education. Howev
Acquired immunodeficiency syndrome: the nurse's legal duty to serve.: J Prof Nurs. 1991 Nov-Dec;7(6):333-40. Unique Identifier : AIDSLINE MED/92113165; Downes J; City College of New York School of Nursing, New York.; Some nurses are reluctant to care for human immunodeficiency virus (HIV)-infected clients because of fear of contagion and discomfort in caring for people with alternate life-styles. Various federal, state, and local antidiscrimination statutes limit the right of the nurse to refuse to care for people with acquired im
[Diagnosis and treatment of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome]: Klin Med (Mosk). 1991 Oct;69(10):33-6. Unique Identifier : AIDSLINE MED/92114427; Vinogradov NA
[Epilepsy seizures in HIV infection. 52 cases]: Presse Med. 1991 Dec 7;20(42):2135-8. Unique Identifier : AIDSLINE MED/92115651; Bartolomei F; Pellegrino P; Dhiver C; Quilichini R; Gastaut JA; Gastaut JL; Service de Neurologie, Hopital Sainte-Marguerite, Marseille.; Fifty-two patients at various stages of human immunodeficiency virus (HIV) infection who had one or several epileptic seizures in the course of that disease were retrospectively studied from 1985 to 1990. Thirty-five percent of these patients were in overt clinical AIDS at the time of the seizure(s). AIDS was revealed
[Dysmyelopoiesis in HIV infection. Improvement in a case with dideoxyinosine (letter)]: Presse Med. 1991 Dec 7;20(42):2163. Unique Identifier : AIDSLINE MED/92115665; Lafeuillade A; Pellegrino P; Chaffanjon P; Delbeke E; Quilichini R
Rosacea-like lesions due to familial Mycobacterium avium-intracellulare infection.: Int J Dermatol. 1991 Jul;30(7):491-7. Unique Identifier : AIDSLINE MED/92120828; Nedorost ST; Elewski B; Tomford JW; Camisa C; Department of Dermatology, Cleveland Clinic Foundation, Ohio.; Mycobacterium avium-intracellulare (MAI) is a non-tuberculous, nonlepromatous or atypical mycobacterium now seen frequently in patients with acquired immunodeficiency syndrome (AIDS). In the past decade, the incidence appears to have increased in non-AIDS patients. Although cutaneous involvement is rare, two brothers
[Anatomo-clinical conference at the Hotel-Dieu in Montreal (clinical conference)]: Union Med Can. 1991 Nov-Dec;120(6):438-43. Unique Identifier : AIDSLINE MED/92124604; Jarry M; Lamarre L; Monte M; Lefebvre B; Vega C; Cadotte M; Departement de medecine, Hotel-Dieu de Montreal.
Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome.: Adv Exp Med Biol. 1991;294:687-90. Unique Identifier : AIDSLINE MED/92125230; Heyes MP; Brew B; Martin A; Markey SP; Price RW; Bhalla RB; Salazar A; Laboratory of Clinical Science, NIMH, Bethesda, Maryland 20892.
Sera from AIDS patients inhibit the responsiveness of normal lymphocytes in allogeneic and autologous mixed lymphocyte cultures.: Allergol Immunopathol (Madr). 1991 Mar-Apr;19(2):89-94. Unique Identifier : AIDSLINE MED/92125252; Puppo F; Stagnaro R; Ruzzenenti R; Indiveri F; Istituto Scientifico di Medicina Interna, Universita di Genova,; Italy.; We analyzed the effects of 10 sera from patients with AIDS on the responsiveness of normal lymphocytes in allogeneic and autologous mixed lymphocyte cultures (MLR and AMLR). Results show that all AIDS sera significantly inhibit lymphocyte responsiveness in either MLR or AMLR of non-T/T and T/T type. Experiments perfor
Behcet's disease associated with HIV infection [see comments]: J Rheumatol. 1991 Sep;18(9):1427-8. Unique Identifier : AIDSLINE MED/92099256; Stein CM; Thomas JE; Department of Clinical Pharmacology, University of Zimbabwe; Medical School, Harare.; The cooccurrence of Behcet s disease and human immunodeficiency virus infection is described in a 33-year-old man who died. If this is not a chance occurrence, then either the constellation of signs that characterize Behcet s disease may be simulated by complications of HIV infection, or else HIV infection causes, or
Proliferation of double-negative (CD4-CD8-) T cells bearing T-cell receptor-alpha beta in a haemophiliac with human immunodeficiency virus type 1 infection and factor VIII inhibitor: functional properties of double-negative T-cell receptor-alpha beta+ T cells.: Br J Haematol. 1991 Nov;79(3):372-6. Unique Identifier : AIDSLINE MED/92088908; Yasukawa M; Hato T; Matsumoto M; Takada K; Fujita S; Kobayashi Y; First Department of Internal Medicine, Ehime University School of; Medicine, Japan.; We present a patient with haemophilia A showing human immunodeficiency virus type 1 (HIV-1) infection and factor VIII inhibitor in whom a novel T-cell subpopulation, double-negative (CD4-CD8-) T cells bearing T-cell receptor (TCR)-alpha beta, proliferated polyclonally in the peripheral blood. An interleukin-2-dependen
Pathology of malignant lymphomas.: Curr Opin Oncol. 1991 Oct;3(5):813-21. Unique Identifier : AIDSLINE MED/92089215; Harris NL; Massachusetts General Hospital, Harvard Medical School, Boston.; Attempts to understand the malignant lymphomas have followed two major lines of investigation: attempts to define the relationship of neoplastic lymphoid cells to stages of normal T- and B-lymphocyte differentiation, and attempts to understand the genetic abnormalities associated with malignant transformation. It is h
Clinical aspects of AIDS-related non-Hodgkin's lymphoma.: Curr Opin Oncol. 1991 Oct;3(5):872-80. Unique Identifier : AIDSLINE MED/92089222; Northfelt DW; Kaplan LD; University of California, San Francisco.; The association of malignant lymphoma with the acquired immunodeficiency syndrome (AIDS) has been recognized since early in the human immunodeficiency virus epidemic. Important clues regarding the etiology of AIDS-related non-Hodgkin s lymphoma (AIDS-NHL) and estimates of the futur
Human papillomavirus-associated anogenital neoplasia and other solid tumors in human immunodeficiency virus-infected individuals.: Curr Opin Oncol. 1991 Oct;3(5):881-5. Unique Identifier : AIDSLINE MED/92089223; Palefsky JM; University of San Francisco, California.; The incidence and variety of solid tumors reported among human immunodeficiency virus (HIV)-infected individuals are increasing. Among the most common of these tumors are anogenital malignant and premalignant tumors associated with human papillomavirus infection. Cervical intraepithelial neoplasia is one such human pa
No retroviremia or pathology in long-term follow-up of monkeys exposed to a murine amphotropic retrovirus.: Hum Gene Ther. 1991 Fall;2(3):215-9. Unique Identifier : AIDSLINE MED/92089235; Cornetta K; Morgan RA; Gillio A; Sturm S; Baltrucki L; O'Reilly R; Anderson WF; Molecular Hematology Branch, National Heart, Lung, and Blood; Institute, National Institutes of Health, Bethesda, MD 20892.; Four monkeys were exposed to a retroviral vector and replication-competent murine amphotropic retrovirus in a bone marrow transplantation/gene transfer protocol (Kantoff et al., 1987). We have studied these animals 2 and 3 years post-transplantation and did not detect replicating virus in serum, peripheral blood monon
Heterosexual and homosexual transmission of hepatitis C virus: relation with hepatitis B virus and human immunodeficiency virus type 1.: Epidemiol Infect. 1991 Dec;107(3):667-72. Unique Identifier : AIDSLINE MED/92090474; Corona R; Prignano G; Mele A; Gentili G; Caprilli F; Franco E; Ferrigno L; Giglio A; Titti F; Bruno C; et al; Istituto Superiore di Sanita, Laboratorio di Epidemiologia e; Biostatistica, Roma.; A seroprevalence study was carried out on 1757 outpatients consecutively seen in a sexually transmitted disease (STD) clinic in order to evaluate the sexual transmission of hepatitis C virus (HCV). A total of 1442 consenting patients were tested for hepatitis C, hepatitis B and human immunodeficiency virus type 1 (HCV
Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival.: J Infect. 1991 Sep;23(2):129-37. Unique Identifier : AIDSLINE MED/92091804; Peters BS; Beck EJ; Anderson S; Coleman D; Coker R; Main J; Migdal C; Harris JR; Pinching AJ; Department of Immunology, St Mary's Hospital Medical School,; London, U.K.; Among 347 AIDS patients seen at St Mary s Hospital, London between 1983 and 1989, cytomegalovirus ( CMV ) disease was observed in 75 (22%). Of these, 58 (77%) had CMV retinitis, 26 (35%) CMV colitis, and 12 (16%) had CMV infect
Human cytomegalovirus infection and trans-activation of HIV-1 LTR in human brain-derived cells [published erratum appears in J Acquir Immune Defic Syndr 1992;5(2):214]: J Acquir Immune Defic Syndr. 1991;4(11):1098-106. Unique Identifier : AIDSLINE MED/92092171; Ho WZ; Song L; Douglas SD; Division of Infectious Diseases and Immunology, Children's; Hospital of Philadelphia, Pennsylvania 19104.; In order to investigate the hypothesis that human cytomegalovirus (HCMV) influences HIV-1 infection of brain cells, we studied primary astrocytes derived from human fetal brains and a neuronal cell line (SK-N-MC). Infection of these cells with two strains of HCMV resulted in expres
Human herpesvirus-6: the latest human herpes virus.: J Oral Pathol Med. 1991 Nov;20(10):465-8. Unique Identifier : AIDSLINE MED/92092186; Bagg J; Department of Oral Surgery, Medicine and Pathology, Dental; School, University of Wales College of Medicine, Cardiff.; Human herpesvirus-6 (HHV-6) was first isolated in 1986 from peripheral blood leukocytes of patients with lymphoproliferative disorders. Although HHV-6 is distinct from the other human herpes viruses, DNA studies have revealed some genomic similarities with cytomegalovirus . It has r
Frequent detection of Epstein-Barr viral deoxyribonucleic acid and absence of cytomegalovirus deoxyribonucleic acid in Hodgkin's disease and acquired immunodeficiency syndrome-related Hodgkin's disease.: Lab Invest. 1991 Dec;65(6):631-6. Unique Identifier : AIDSLINE MED/92092650; Samoszuk M; Ravel J; Pathology Department, University of California, Irvine.; Epstein-Barr viral DNA (EBV DNA) has been detected in 20 to 58% of Hodgkin s disease tumors analyzed by Southern blotting or polymerase chain reaction (PCR). Because patients with Hodgkin s disease are generally immunodepressed, it is possible that the EBV is not directly involved in the pathogenesis of Hodgkin s dise
The ALIVE study, a longitudinal study of HIV-1 infection in intravenous drug users: description of methods and characteristics of participants.: NIDA Res Monogr. 1991;109:75-100. Unique Identifier : AIDSLINE MED/92093062; Vlahov D; Anthony JC; Munoz A; Margolick J; Nelson KE; Celentano DD; Solomon L; Polk BF; Department of Epidemiology, Johns Hopkins School of Hygiene and; Public Health, Baltimore, MD 21205.
Serological prevalence of hepatitis C virus in a population of subjects with human immunodeficiency virus infection [letter]: Postgrad Med J. 1991 Aug;67(790):777. Unique Identifier : AIDSLINE MED/92093819; Lafeuillade A; Zandotti C; Tamalet C; Quilichini R; Gastaut JA
In vitro and in vivo evaluation of two factor VIII concentrates virally inactivated by solvent-detergent or by pasteurization.: Acta Clin Belg. 1991;46(5):298-304. Unique Identifier : AIDSLINE MED/92095002; Peerlinck K; Arnout J; Tamise M; Vanherle A; Fondu P; Vermylen J; Center for Thrombosis and Vascular Research, Katholieke; Universiteit Leuven.; The present study compares two new factor VIII preparations currently used in the treatment of haemophilia. A Factor VIII was partially purified from plasma obtained from unpaid voluntary Belgian donors in the blood transfusion centers of Lille and Amsterdam and virus-inactivated by exposure to solvent-detergent (FVII
Visceral leishmaniasis in an adult with HIV infection.: Acta Clin Belg. 1991;46(5):324-6. Unique Identifier : AIDSLINE MED/92095005; Chew SL; Bedert L; Zachee P; Verbraeken H; Colebunders RL; Department of Internal Medicine, Stuivenberg General Hospital,; Antwerp,Belgium.; We present the first case of visceral leishmaniasis (VL) in a Spanish patient with HIV infection living in Belgium . After four weeks of stibogluconate and zidovudine treatment, the initially low CD4 count improved, and the splenomegaly regressed. VL is becoming frequently reported
Glove use by health care workers: results of a tristate investigation.: Am J Infect Control. 1991 Oct;19(5):228-32. Unique Identifier : AIDSLINE MED/92095498; Kaczmarek RG; Moore RM Jr; McCrohan J; Arrowsmith-Lowe JT; Caquelin C; Reynolds C; Israel E; Center for Devices and Radiological Health, Food and Drug; Administration, Rockville, MD 20852.; The Center for Devices and Radiological Health, in collaboration with the state health departments of Iowa, Maryland, and Massachusetts, conducted a multi-state, multi-institutional investigation of glove use by health care workers (HCWs). Twenty-two hospitals and four ambulatory care centers were included in the inve
Hepatitis C infection in the health care setting. I. Low risk from parenteral exposure to blood of human immunodeficiency virus-infected patients.: Am J Infect Control. 1991 Oct;19(5):237-42. Unique Identifier : AIDSLINE MED/92095500; Wormser GP; Forseter G; Joline C; Tupper B; O'Brien TA; Department of Medicine, New York Medical College, Valhalla 10595.; Many patients with human immunodeficiency virus (HIV) infection have also been infected with hepatitis C virus (HCV). To understand better the epidemiology of HCV infection in the health care setting, HCV antibody testing was done for 125 health care workers who had experienced parenteral exposures to blood of HIV-inf
Immune responses in lentivirus-infected animals.: Curr Opin Immunol. 1991 Aug;3(4):559-63. Unique Identifier : AIDSLINE MED/92096152; Letvin NL; Harvard Medical School, Southborough, Massachusetts.
Immunovirology of transforming viruses.: Curr Opin Immunol. 1991 Oct;3(5):665-73. Unique Identifier : AIDSLINE MED/92096158; Klein G; Karolinska Institutet, Stockholm, Sweden.; The paradigmatic shift in cellular immunology, initiated by the realization that cytotoxic T lymphocytes recognize major histocompatibility complex class I antigens that carry endogenous (including virally encoded) protein-derived peptides in a special groove, has made a strong impact on the immunopathology of virus-a
Investigating the presence of HIV sequences and the distribution of virological markers in hemophiliacs and their sexual partners.: Ann Hematol. 1991 Dec;63(6):315-9. Unique Identifier : AIDSLINE MED/92096495; Cardoso M da S; Epple S; Koerner K; Kubanek B; Ellbruck D; Seifried E; German Red Cross Blood Bank Ulm.; In this study, we report the investigation of a hemophiliac cohort, in which the last HIV-1 seroconversion occurred in 1985. We wanted to evaluate whether 5 years later the results of serological screening and polymerase chain reaction (PCR) technology would match. We examined 61 German patients with congenital defici
CDC calls for AIDS testing for hospital patients.: Ohio Med. 1991 Nov;87(11):559. Unique Identifier : AIDSLINE MED/92100467
Phenotype of intramyocardial leukocytic infiltrates in acquired immunodeficiency syndrome (AIDS): a postmortem immunohistochemical study in 34 consecutive cases.: Mod Pathol. 1991 Sep;4(5):559-65. Unique Identifier : AIDSLINE MED/92100726; Parravicini C; Baroldi G; Gaiera G; Lazzarin A; Institute of Biomedical Science, Medical School, University of; Milan, Italy.; In 34 hearts, obtained at autopsy in consecutive AIDS cases, leukocytic phenotype and presence of viral antigens were investigated in paraffin-embedded (34 cases) and frozen myocardial sections (10 cases) by different monoclonal antibodies. The total frequency of focal lymphocytic infiltrates with and without myocell
Human papillomavirus types and recurrent cervical warts in immunocompromised women.: Mod Pathol. 1991 Sep;4(5):632-6. Unique Identifier : AIDSLINE MED/92100739; Nuovo GJ; Babury R; Calayag PT; Department of Pathology, SUNY, Stony Brook.; Little is known about the host s immunological response to human papillomavirus (HPV) infection, which is an important co-factor in genital tract cancers. This study analyzed the HPV type in pre- and posttreatment tissues in immunocompromised women with cervical squamous intraepithelial lesions (SILs) that recurred af
CMV pneumonia and response to ganciclovir treatment in an AIDS patient.: Respir Med. 1991 Sep;85(5):437-9. Unique Identifier : AIDSLINE MED/92100907; Lundgren JD; Vestbo J; Junge J; Mathiesen LR; Department of Infectious Diseases, Hvidovre Hospital, University; of Copenhagen, Denmark.
CDC to list exposure-prone procedures for HIV-infected physicians.: Tex Med. 1991 Nov;87(11):20. Unique Identifier : AIDSLINE MED/92101207
[Epidemiology and clinical aspects of FIV infection in Bavaria]: Tierarztl Prax. 1991 Oct;19(5):545-51. Unique Identifier : AIDSLINE MED/92101251; Hartmann K; Hinze K; I. Medizinischen Tierklinik, Ludwig-Maximilians-Universitat; Munchen.; In a comprehensive epidemiological study at the I. Medizinische Tierklinik at the Ludwig-Maximilians-University in Munich within the last two years, the spread and frequency of FIV infection as well as the clinical symptoms of FIV positive cats were evaluated. 5129 serum samples from clinically healthy and ill cats we
[Lymphadenopathy as an AIDS marker in the practice of the surgeon]: Vestn Khir Im I I Grek. 1991 Apr;146(4):125-7. Unique Identifier : AIDSLINE MED/92101368; Trutnev PV; Marerva G; Bigirimana V
Characterization of rhesus macaque B-lymphoblastoid cell lines infected with simian type D retrovirus.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):899-909. Unique Identifier : AIDSLINE MED/92102766; van Kuyk RW; Acevedo RA; Torres JV; Levy NB; Planelles V; Munn RJ; Unger RE; Gardner MB; Luciw PA; Department of Medical Pathology, University of California, Davis; 95616.; A simian type D retrovirus designated SRV induces a fatal immunosuppressive disease in rhesus macaques. This syndrome shows many clinical similarities to acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus-infected individuals. To investigate the mechanisms of immune dysfunction in SRV infection,
Experimental vaccine protection against feline immunodeficiency virus.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):911-22. Unique Identifier : AIDSLINE MED/92102767; Yamamoto JK; Okuda T; Ackley CD; Louie H; Pembroke E; Zochlinski H; Munn RJ; Gardner MB; Department of Medicine, School of Veterinary Medicine, University; of California, Davis 95616.; Infection of domestic cats with the feline immunodeficiency virus (FIV) represents an important veterinary health problem and a useful animal model for the development of vaccines against acquired immunodeficiency syndrome (AIDS). Two experimental FIV vaccines have been developed; one consisting of fixed infected cell
Mechanism of vasoconstriction in the rat's tail when warmed locally.: J Appl Physiol. 1991 Nov;71(5):1758-63. Unique Identifier : AIDSLINE MED/92104903; Sakurada S; Shido O; Nagasaka T; Department of Physiology, School of Medicine, Kanazawa; University, Japan.; The vascular response of the tail to local warming was investigated in urethan-anesthetized rats whose colonic temperature was maintained at 39.5 degrees C with an intravenous thermode at an ambient temperature of 23 degrees C. The tail, covered with thin latex tubing, was immersed in temperature-controlled water init
Analysis of DNA restriction fragments and polymerase chain reaction products towards detection of the AIDS (HIV-1) virus in blood.: J Chromatogr. 1991 Oct 18;559(1-2):267-83. Unique Identifier : AIDSLINE MED/92105253; Schwartz HE; Ulfelder K; Sunzeri FJ; Busch MP; Brownlee RG; Beckman Instruments, Inc., Palo Alto, CA 94304.; A high-performance capillary electrophoresis system with a polysiloxane-coated capillary and polymeric buffer additives was investigated for the analysis of DNA restriction fragments and polymerase chain reaction (PCR) products. Mobility data and Ferguson plots of the DNA fragments at different polymer (hydroxypropylm
Cutaneous lesions of hemophagocytic syndrome in a patient with T-cell lymphoma and active Epstein-Barr infection.: J Am Acad Dermatol. 1991 Nov;25(5 Pt 2):919-24. Unique Identifier : AIDSLINE MED/92105512; Smith KJ; Skelton HG 3d; Giblin WL; James WD; Walter Reed Army Institute of Research, Washington, DC.; The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali
Esophageal stricture after cytomegalovirus ulcer treated with ganciclovir.: J Clin Gastroenterol. 1991 Dec;13(6):678-81. Unique Identifier : AIDSLINE MED/92105672; Goodgame RW; Ross PG; Kim HS; Hook AG; Sutton FM; Department of Medicine, Baylor College of Medicine, Houston,; Texas.; A 49-year-old man with the acquired immune deficiency syndrome (AIDS) developed epigastric pain, nausea, vomiting, and gastrointestinal bleeding secondary to a cytomegalovirus ( CMV )-induced ulceration in the distal esophagus
[Clinical studies on lung cancer]: Nippon Naika Gakkai Zasshi. 1991 Sep 10;80(9):1356-68. Unique Identifier : AIDSLINE MED/92105835; Kimura I; Department of Internal Medicine, Okayama University Medical; School.
Visceral leishmaniasis in an HIV-infected patient: clinical features and response to treatment.: Klin Wochenschr. 1991 Oct 31;69(17):793-6. Unique Identifier : AIDSLINE MED/92106754; Fenske S; Stellbrink HJ; Albrecht H; Greten H; Medizinische Kernklinik und Poliklinik, Universitatskrankenhaus; Eppendorf, Hamburg.; We report the case of 43-year-old homosexual patient with HIV infection and a history of travel to the Far East in whom visceral leishmaniasis was the first infectious complication. Symptoms were fever, malaise, weight loss, hepatosplenomegaly, generalized lymphadenopathy, and oral
How AIDS has shaped CDC's prevention policies.: N J Med. 1991 Dec;88(12):914-6. Unique Identifier : AIDSLINE MED/92107416; Valdiserri RO; National Center for Prevention Services, Centers for Disease; Control, Atlanta, GA 30333.; The Centers for Disease Control HIV prevention strategy has developed into a plan that recognizes the complexity of human behavior change, the diversity of partners needed to combat this enemy, and the importance of integrating HIV prevention efforts into other prevention, medical, and social services.
Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein.: Nucleic Acids Res. 1991 Dec 25;19(24):6691-8. Unique Identifier : AIDSLINE MED/92107649; Vink C; Yeheskiely E; van der Marel GA; van Boom JH; Plasterk RH; Division of Molecular Biology, The Netherlands Cancer Institute,; Amsterdam.; Before integration of the human immunodeficiency virus (HIV) DNA, two nucleotides are removed from the 3 ends of the viral DNA by the integrase (IN) protein. We studied the chemistry of this reaction, and found that IN mediates site-specific hydrolysis of a phosphodiester bond, resulting in release of a dinucleotide.
[Prevention of genital erosions during treatments with foscarnet of cytomegalovirus infections in AIDS (letter)]: Presse Med. 1991 Nov 23;20(39):1951. Unique Identifier : AIDSLINE MED/92107807; Lowenstein W; Fadlallah JP; Roudiere L; Deneux C; Haas C; Durand H
[Peripheral neuropathy in HTLV-I-associated myelopathy (letter)]: Presse Med. 1991 Nov 30;20(41):2109. Unique Identifier : AIDSLINE MED/92107853; Pestre P; Olivares JP; Planche D; Pellissier JF; Gallais H
Human immunodeficiency virus glycoprotein (gp120) infused into rat brain induces interleukin 1 to elevate pituitary-adrenal activity and decrease peripheral cellular immune responses.: Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11246-50. Unique Identifier : AIDSLINE MED/92107926; Sundar SK; Cierpial MA; Kamaraju LS; Long S; Hsieh S; Lorenz C; Aaron M; Ritchie JC; Weiss JM; Department of Psychiatry, Duke University Medical Center, Durham,; NC 27710.; Intracerebroventricular (i.c.v.) infusion of glycosylated recombinant gp120, the envelope protein of human immunodeficiency virus, in various doses (100 ng to 4 micrograms) resulted in detection of interleukin 1 (IL-1) activity in a high percentage (61%; 33 of 54) of rat brains, whereas IL-1 was very rarely detected i
Synthesis and evaluation of antiviral activity of L-acosamine and L-ristosamine nucleosides of furanose configuration.: Acta Chem Scand. 1991 Jul;45(6):616-20. Unique Identifier : AIDSLINE MED/92110115; Lau J; Pedersen EB; Nielsen CM; Department of Chemistry, Odense University, Denmark.; Mercuric-catalyzed hydrolysis of acetylated L-rhamnal 1 gives an alpha,beta-unsaturated aldehyde 2. 1,4-Addition of DBU-phthalimide salt with concomitant acetyl shift resulted in L-ribo and L-arabino isomers of 5-O-acetyl-2,3,6-trideoxy-3-phthalimido-hexofuranose 3 and 4. After acetylation at the anomeric center, coup
Dronabinol found to stimulate appetite and prevent weight loss in patients with HIV infection [news]: Oncology (Huntingt). 1991 Nov;5(11):100, 103. Unique Identifier : AIDSLINE MED/92110136
[Malaria infection during childbirth and in newborns in Becedi (Ivory Coast)]: Bull Soc Pathol Exot. 1991;84(3):257-65. Unique Identifier : AIDSLINE MED/92110877; Bachschmid I; Soro B; Coulibaly A; Philippe E; Kingston L; Kien T; Rey JL; Hopital Protestant de Dabou, Maternite de Becedi.; Authors studied the parasitological and serological status of 108 new-born children from 102 deliveries during the 2nd term of 1987 at the Becedi Maternity Hospital in Ivory Coast . The parasitism frequency of different studied bloods (mother, cord, delivery) is varying from 8
[A case of adult T cell leukemia/lymphoma with motor and sensory polyneuropathy]: Rinsho Shinkeigaku. 1991 Aug;31(8):853-7. Unique Identifier : AIDSLINE MED/92111043; Nakano S; Ohnishi A; Oishi T; Murai Y; Nagata K; Department of Neurology, University of Occupational and; Environmental Health.; A 62-year-old man was admitted to our hospital because of two months continuing paresthesia and muscle weakness of distal portions of the four limbs. On general physical examination, skin lesions, lymphadenopathy and hepatosplenomegaly were not found. Neurological examination revealed moderate weakness in the bilatera
Condom conundrums: Part I.: Cutis. 1991 Nov;48(5):359-60. Unique Identifier : AIDSLINE MED/92111306; Fisher AA; New York University Medical School, New York.
New guidelines for preventing HIV/HBV transmission [news]: Int Nurs Rev. 1991 Nov-Dec;38(6):167-8. Unique Identifier : AIDSLINE MED/92112403
CDC open meeting to discuss invasive procedures under consideration for designation as exposure-prone and not exposure-prone.: J Dent Educ. 1991 Dec;55(12):810-3. Unique Identifier : AIDSLINE MED/92113154; Kalkwarf KL; University of Texas Health Science Center at San Antonio, School; of Dentistry 78284-7906.
Epstein-Barr virus infection in oral hairy leukoplakia: virus replication in the absence of a detectable latent phase.: J Gen Virol. 1991 Dec;72 ( Pt 12):3035-46. Unique Identifier : AIDSLINE MED/92113547; Niedobitek G; Young LS; Lau R; Brooks L; Greenspan D; Greenspan JS; Rickinson AB; Department of Cancer Studies, University of Birmingham Medical; School, U.K.; Epstein-Barr virus (EBV) infects both B lymphocytes and oropharyngeal epithelium, and it has been argued that the true reservoir of virus persistence in vivo is the self-renewing basal epithelial compartment. The identification of oral hairy leukoplakia (HL) of AIDS patients as a clinically apparent focus of EBV repli
HIV-infected intravenous drug users in methadone maintenance treatment: clinical problems and their management.: J Psychoactive Drugs. 1991 Apr-Jun;23(2):217-24. Unique Identifier : AIDSLINE MED/92113801; Ferrando SJ; Batki SL; Substance Abuse Services, San Francisco General Hospital,; California 94110.; Infection with the human immunodeficiency virus (HIV) is a significant and growing problem among intravenous drug users (IVDUs), both from the standpoint of personal morbidity and public health concerns regarding spread of the virus. Most HIV-infected IVDUs are opioid addicts. The most common form of long-term treatme
CDC issues guidelines for patient testing.: Maine Nurse. 1991 Winter;78(4):3. Unique Identifier : AIDSLINE MED/92114538; Richardson DR
Transactivation of heterologous promoters by HIV-1 tat.: Nucleic Acids Res. 1991 Dec;19(25):7225-9. Unique Identifier : AIDSLINE MED/92115574; Han P; Brown R; Barsoum J; Biogen, Inc., Fourteen Cambridge Center, MA 02142.; To determine whether HIV-1 tat can transactivate a heterologous promoter lacking HIV sequences other than the TAR element, TAR was placed downstream of the chicken beta-actin promoter. Tat increased expression directed by the actin-TAR promoter to a degree equal to tat induction of the HIV-1 LTR. Optimal transactivati
Effect of thymopentin on peripheral blood T-lymphocytes subsets and on the clinical course of the disease in patients affected by multiple sclerosis.: Riv Neurol. 1991 May-Jun;61(3):110-5. Unique Identifier : AIDSLINE MED/92116115; Cognazzo A; Seliak D; Fruttero A; Divisione di Neurologia, Ospedale S.S. Annunziata, Savigliano CN.; The effect on peripheral T-lymphocytes of Thymopentin (TP-5), asynthetic pentapeptide reproducing the biological activity of Thymopoietin, is known in Herpes Simplex infections and in Rheumatoid Arthritis. The aim of this study was to observe the effect of TP-5 on the OKT4 and OKT8 lymphocytes in Multiple Sclerosis. T
[Peripheral nerve damage in HIV infection]: Riv Neurol. 1991 May-Jun;61(3):97-104. Unique Identifier : AIDSLINE MED/92116120; Parisi L; Calandriello E; Valente G; Terracciano ME; Angele B; Amabile G; Morocutti C; Istituto di Clinica delle Malattie Nervose e Mentali, Universita; La Sapienza, Roma.; A critical review of the literature concerning PNS involvement in HIV infection was carried out. This complication was detected a short time ago (1982) and therefore a common classification is not yet available. The authors, through an analysis of the cases reported in literature, suggest a nosographic classification
HIV guidelines available for health care providers. Do you know how to respond to your patients' concerns for protection from HIV exposure from health care providers?: Tex Nurs. 1991 Sep;65(8):8-9. Unique Identifier : AIDSLINE MED/92116380
Avarol restores the altered prostaglandin and leukotriene metabolism in monocytes infected with human immunodeficiency virus type 1.: Virus Res. 1991 Nov;21(3):213-23. Unique Identifier : AIDSLINE MED/92116636; Schroder HC; Begin ME; Klocking R; Matthes E; Sarma AS; Gasic M; Muller WE; Abteilung Angewandte Molekularbiologie, Universitat, Mainz,; Germany.; Infection of monocytes with human immunodeficiency virus type 1 (HIV-1) (strain Ada-M) caused increased levels of leukotriene B4 (LTB4) and prostaglandin E2 (PGE2) in vitro. These two products result from the activities of the two enzymes cyclooxygenase and 5-lipoxygenase. The addition of the sesquiterpenoid hydroquin
In vitro evaluation of the synergistic antiviral effects of acemannan in combination with azidothymidine and acyclovir.: Mol Biother. 1991 Dec;3(4):214-23. Unique Identifier : AIDSLINE MED/92118251; Kahlon JB; Kemp MC; Yawei N; Carpenter RH; Shannon WM; McAnalley BH; Department of Biochemistry, Southern Research Institute,; Birmingham, Alabama.; The antiviral effects of selected combinations between acemannan (ACE-M), a long-chained, polydispersed, beta-(1,4)-acetylated mannan, were tested in combination with azidothymidine ( AZT ) and acyclovir (ACY) in
Effect of HIV-1 and cytomegalovirus in bronchoalveolar lavage cells on the transfer factor for lung carbon monoxide in AIDS patients.: AIDS. 1991 Nov;5(11):1333-8. Unique Identifier : AIDSLINE MED/92118261; Clarke JR; Fleming J; Donegan K; Moss FM; Nieman R; Williamson JD; Mitchell DM; Department of Medical Microbiology, St Mary's Hospital Medical; School, Paddington, London, UK.; Abnormalities in pulmonary function tests have been observed in AIDS patients with pulmonary disease. In this study, the polymerase chain reaction (PCR) was used to determine if the reductions in transfer factor for lung carbon monoxide (TLCO) were due to the presence of HIV-1 or cytom
Itraconazole versus ketaconazole in the treatment of oral and oesophageal candidosis in patients infected with HIV.: AIDS. 1991 Nov;5(11):1367-71. Unique Identifier : AIDSLINE MED/92118267; Smith DE; Midgley J; Allan M; Connolly GM; Gazzard BG; AIDS Unit, St. Stephens Clinic, London, UK.; To determine the efficacy and toxicity of two systemically active antifungal agents in the treatment of buccal and oesophageal candidiasis 111 HIV-infected patients with microscopically-confirmed candidiasis were randomized to receive either 200 mg itraconazole once a day or 200 mg ketoconazole twice a day for 28 days
Prevalence and transmission of simian immunodeficiency virus and simian T-cell leukemia virus in a semi-free-range breeding colony of mandrills in Gabon [letter]: AIDS. 1991 Nov;5(11):1385-6. Unique Identifier : AIDSLINE MED/92118271; Estaquier J; Peeters M; Bedjabaga L; Honore C; Bussi P; Dixson A; Delaporte E
A murine model for rectal transmission of retrovirus [letter]: AIDS. 1991 Nov;5(11):1388-9. Unique Identifier : AIDSLINE MED/92118273; Ushijima H; Koike H; Unten S; Ami Y; Tsuchie H; Yoshikura H
Statistics from the World Health Organization and the Centers for Disease Control.: AIDS. 1991 Nov;5(11):1399-403. Unique Identifier : AIDSLINE MED/92118281
New synthesis of 2',3'-didehydro-2',3'-dideoxynucleosides.: Acta Chem Scand. 1991 Nov;45(10):1060-3. Unique Identifier : AIDSLINE MED/92118554; Abdel-Megied AE; Hansen P; Pedersen EB; Nielsen CM; Department of Chemistry, Odense University, Denmark.; The 3 -iodonucleoside 4 and the 3 -O-methylsulfonylthymidine 9 have been synthesized by condensation of silylated uracils 2 with methyl 5-O-tert-butyldiphensilyl-2,3-dideoxy-3-iodo-D-threo-pentofuran oside (3) and methyl 5-O-tert-butyldiphenylsilyl-2-deoxy-3-methylsulfonyl-D-erythro- pentofuranoside (8), respectively.
Elevated serum beta-glucuronidase activity in acquired immunodeficiency syndrome.: Clin Chim Acta. 1991 Jul 15;199(3):311-6. Unique Identifier : AIDSLINE MED/92119798; Saha AK; Glew RH; Kotler DP; Omene JA; Department of Biochemistry, School of Medicine, University of New; Mexico, Albuquerque.
Cytomegalovirus endocervicitis diagnosed by cervical smear [see comments]: Diagn Cytopathol. 1991;7(6):625-7. Unique Identifier : AIDSLINE MED/92120050; Gideon K; Zaharopoulos P; Division of Cytopathology, University of Texas Medical Branch,; Galveston 77550.; Cytomegalovirus ( CMV ) cytologic changes were found in a routine cervical smear of a 21-yr-old HIV-negative woman, 4 wk post partum. The CMV changes were associated with columnar cervical epithelium. The case is reported because of the rarity of such an occurrenc
[Transmission of viral infections during transfusion of blood and its components]: Gematol Transfuziol. 1991 Jun;36(6):25-7. Unique Identifier : AIDSLINE MED/92120427; Agranenko VA; Krizhevskaia IuV
[HIV infection. Dithiocarb treatment in AIDS is unsuccessful (news)]: Fortschr Med. 1991 Nov 20;109(33):18. Unique Identifier : AIDSLINE MED/92120619
[Massive and multi-transfusions in polytraumatized patients: long-term serologic markers of hepatitis B, hepatitis C and AIDS]: Infusionstherapie. 1991 Oct;18(5):248-55. Unique Identifier : AIDSLINE MED/92120787; Schneck HJ; Dobler G; Hundelshausen B; Nathrath M; Drescher M; Institut fur Anaesthesiologie, Technischen Universitat; Munchen.; 302 out of 712 (42%) consecutive polytraumatized ICU patients received ten or more units of stored blood during primary and/or intensive care (1982 to 1987) treatment. 120 of the 197 surviving patients with an average number of transfusions of 23 (10 to 89) units were followed up after a mean interval of 70 (20 to 104
Central nervous system pathology in children with AIDS. A review.: Ir J Med Sci. 1991 Sep;160(9):277-81. Unique Identifier : AIDSLINE MED/92120873; Keohane C; Gray F; Pathology Department, Cork Regional Hospital, Wilton.
Clinical, hematologic, and survival data from cats infected with feline immunodeficiency virus: 42 cases (1983-1988).: J Am Vet Med Assoc. 1991 Oct 1;199(7):913-6. Unique Identifier : AIDSLINE MED/92120983; Fleming EJ; McCaw DL; Smith JA; Buening GM; Johnson C; Department of Veterinary Medicine and Surgery, College of; Veterinary Medicine, University of Missouri, Columbia 65211.; A retrospective study of stored feline serum samples was done to determine the infection rate of feline immunodeficiency virus in cats in central Missouri. Infected cats were compared with uninfected cats subjected to the same selection criteria on the basis of signalment, clinical signs, and CBC abnormalities. A sign
Does MNA need an AIDS Committee?: Mass Nurse. 1991 Aug;61(6):4. Unique Identifier : AIDSLINE MED/92122963; Huyett JW
[Mycoses as opportunistic infections in AIDS patients]: Med Klin. 1991 Dec;86 Suppl 1:19-22. Unique Identifier : AIDSLINE MED/92123036; Viviani MA; Instituto di Igiene, Milano, Italien.; Since January 1985 more than 100 patients with deep fungal infections have been treated with itraconazole (200 to 400 mg/day) in Northern Italy . Evaluation of the drug efficacy and tolerance was possible in one patient with sporotrichosis, in 34 with aspergillosis, and in 36 with cr
[The treatment of aspergillosis, cryptococcosis and histoplasmosis in immunocompromised patients. Report of experience in the United States]: Med Klin. 1991 Dec;86 Suppl 1:8-10. Unique Identifier : AIDSLINE MED/92123039; Hostetler JS; Stevens DA; California Institute for Medical Research, Santa Clara Valley; Medical Center, San Jose.; Itraconazole has emerged as an important new oral agent in the treatment of systemic fungal infections. We report a summary of available data on its use in aspergillosis, cryptococcosis and histoplasmosis compiled in the United States with particular attention to the immunocompromised
AIDS and science [letter; comment]: N Y State Dent J. 1991 Dec;57(10):8-9. Unique Identifier : AIDSLINE MED/92123554; Fein SI
Gonococcal infection and human fertility in sub-Saharan Africa [published erratum appears in Proc R Soc Lond B Biol Sci 1992 Mar 23;247(1320):223]: Proc R Soc Lond B Biol Sci. 1991 Nov 22;246(1316):173-7. Unique Identifier : AIDSLINE MED/92123725; Brunham RC; Garnett GP; Swinton J; Anderson RM; Parasite Epidemiology Research Group, Imperial College, London; University, U.K.; An analysis is presented of the influence of Neisseria gonorrhoeae on human population growth in regions of sub-Saharan Africa where gonococcal infections are prevalent in sexually active adults. Combining epidemiological and demographic data within the framework of a mathematical model, we show that gonorrhoea has a
Should health-care workers undergo mandatory HIV screening?: Todays OR Nurse. 1991 Nov;13(11):43. Unique Identifier : AIDSLINE MED/92124511
Rifabutin in combination with clofazimine, isoniazid and ethambutol in the treatment of AIDS patients with infections due to opportunist mycobacteria. Groupe d'Etude et de Traitement des Infections a Mycobacteries Resistantes.: Tubercle. 1991 Sep;72(3):168-75. Unique Identifier : AIDSLINE MED/92124586; Dautzenberg B; Truffot C; Mignon A; Rozenbaum W; Katlama C; Perronne C; Parrot R; Grosset J; Service de Pneumologie, Groupe Hospitalier Pitie Salpetriere,; Paris, France.; 96 AIDS patients with fever and either acid-fast bacilli on microscopic examination of bacteriological samples or mycobacteria isolated by culture were treated with a daily 4-drug combination of 7-10 mg/kg rifabutin, 5 mg/kg isoniazid, 20 mg/kg ethambutol and 100 mg clofazimine. 46 patients were excluded from efficacy
Quinolinic acid concentrations are increased in cerebrospinal fluid of Rhesus macaques (Macaca mulatta) naturally infected with simian retrovirus type-D.: Adv Exp Med Biol. 1991;294:555-8. Unique Identifier : AIDSLINE MED/92125200; Heyes MP; Gravell M; April M; Blackmore D; London WT; Yergey JA; Markey SP; Laboratory of Clinical Science, NIMH, Bethesda, Maryland 20892.
[VIIth International AIDS Congress if Florence]: TVZ. 1991 Oct 24;(20):744-5. Unique Identifier : AIDSLINE MED/92088476; Hoeksema K; Esman H; Quint G
RNA tumor virus update.: Cancer Cells. 1991 Sep;3(9):351-4. Unique Identifier : AIDSLINE MED/92088812; Linial ML; Emerman M; Fred Hutchinson Cancer Research Center, Seattle, Washington; 98104.
[Lymphoproliferative diseases of granular lymphocytes]: Haematologica. 1991 Jun;76 Suppl 3:65-71. Unique Identifier : AIDSLINE MED/92090867; Zambello R; Semenzato G; Istituto di Medicina Clinica, Universita degli Studi di Padova.
HIV-1 env sequence variation in brain tissue of patients with AIDS-related neurologic disease.: J Acquir Immune Defic Syndr. 1991;4(11):1082-92. Unique Identifier : AIDSLINE MED/92092169; Pang S; Vinters HV; Akashi T; O'Brien WA; Chen IS; Department of Medicine, UCLA School of Medicine, Los Angeles,; California.; We investigated sequence variation in the human immunodeficiency virus type 1 (HIV-1) env gene region that encodes the fourth disulfide-bonded domain of the external membrane glycoprotein, gp120, among three HIV-1 isolates from patients with AIDS-related neurologic disease. The sequences of HIV-1 isolated directly fro
Prevalence of HIV infection in seronegative high-risk individuals examined by virus isolation and PCR.: J Acquir Immune Defic Syndr. 1991;4(11):1107-11. Unique Identifier : AIDSLINE MED/92092172; Nielsen C; Teglbjaerg LS; Pedersen C; Lundgren JD; Nielsen CM; Vestergaard BF; Department of Virology, Statens Seruminstitut, Copenhagen,; Denmark.; HIV seronegative individuals with high-risk behavior were tested for HIV infection by sensitive virus isolation techniques using T4 lymphocytes and monocyte/macrophages, and by detection of proviral DNA using PCR with three different sets of nested primers. No evidence of HIV infection was found among the 31 seronegat
The dynamics of CD4+ T-lymphocyte decline in HIV-infected individuals: a Markov modeling approach.: J Acquir Immune Defic Syndr. 1991;4(11):1141-7. Unique Identifier : AIDSLINE MED/92092177; Longini IM Jr; Clark WS; Gardner LI; Brundage JF; Division of Biostatistics, School of Public Health, Emory; University, Atlanta, Georgia 30322.; We modeled the decline of CD4+ T-lymphocytes (T4 cells) in HIV-infected individuals with a continuous-time Markov process. The model partitions the HIV infection period into six progressive T4-cell count intervals (states), followed by a seventh state: a definitive HIV-infection end point, i.e., AIDS diagnosis or Walt
Role of insulin-like growth factor-1 in spontaneous proliferation of HTLV-infected lymphocytes [letter]: J Acquir Immune Defic Syndr. 1991;4(11):1165-6. Unique Identifier : AIDSLINE MED/92092184; Lal RB; Rudolph DL; Folks TM; Hooper C
[Are zinc and selenium markers of worsening in HIV infected subjects? (letter)]: Presse Med. 1991 Nov 2;20(35):1737. Unique Identifier : AIDSLINE MED/92093899; Allavena C; Dousset B; May T; Amiel C; Nabet-Belleville F; Canton P
A study of nineteen immunocompromised patients with extensive skin lesions caused by Pseudomonas aeruginosa with and without bacteremia.: Acta Derm Venereol. 1991;71(5):411-5. Unique Identifier : AIDSLINE MED/92095018; el Baze P; Thyss A; Vinti H; Deville A; Dellamonica P; Ortonne JP; Department of Bacteriology, Pasteur Hospital School of Medicine,; Nice, France.; Nineteen immunocompromised patients with extensive skin lesions caused by Pseudomonas aeruginosa with or without P. aeruginosa bacteremia were analysed. Patients whose lesions originated in the skin were in the majority (14 patients). Skin lesions were located at the site of entry of bacteria (apocrine areas in 12 pat
HIV infection and loss of treponemal test reactivity [letter] [see comments]: Acta Derm Venereol. 1991;71(5):458. Unique Identifier : AIDSLINE MED/92095033; Sjovall P; Flamholc L; Kroon BM; Bredberg A
Antabuse (disulfiram) and AIDS.: Alcohol Clin Exp Res. 1991 Oct;15(5):900-1. Unique Identifier : AIDSLINE MED/92095476; Gallant DM; Head-Dunham R; Department of Psychiatry and Neurology, Tulane University School; of Medicine, Veterans Administration Medical Center, New Orleans,; LA.
HIV/AIDS pathogenesis and treatment: new twists and turns.: Curr Opin Immunol. 1991 Aug;3(4):537-42. Unique Identifier : AIDSLINE MED/92096148; Pinching AJ; St Mary's Hospital Medical School, London, UK.; This review focuses on some new insights into human immunodeficiency virus pathogenesis, as it affects CD4 lymphocytes and other key cells in the immune system. It also critically reviews recent progress in anti-retroviral therapy.
Predominance of distinct viral genotypes in brain and lymph node compartments of HIV-1-infected individuals.: Viral Immunol. 1991 Summer;4(2):123-31. Unique Identifier : AIDSLINE MED/92102542; Haggerty S; Stevenson M; Department of Pathology and Microbiology, University of Nebraska; Medical Center, Omaha.; A modified polymerase chain reaction protocol was used to amplify the entire envelope-coding region of HIV-1 directly from brain and lymph node tissue obtained at autopsy from three HIV-1-infected individuals. Molecular analysis of amplified DNA by digestion with 18 restriction endonucleases, singly and in combination
Pharmacy World Congress highlights international pharmacy practice.: Am Pharm. 1991 Dec;NS31(12):26-7. Unique Identifier : AIDSLINE MED/92109178
Damage control [news]: Hastings Cent Rep. 1991 Nov-Dec;21(6):47. Unique Identifier : AIDSLINE MED/92112489
IS901, a new member of a widespread class of atypical insertion sequences, is associated with pathogenicity in Mycobacterium avium.: Mol Microbiol. 1991 Sep;5(9):2265-72. Unique Identifier : AIDSLINE GENBANK/X52372; Kunze ZM; Wall S; Appelberg R; Silva MT; Portaels F; McFadden JJ; Molecular Microbiology Group, School of Biological Sciences,; University of Surrey, Guildford, UK.; An insertion sequence (IS901), found in pathogenic strains of Mycobacterium avium, but absent in M. avium complex isolates from patients with acquired immune deficiency syndrome (AIDS), has been isolated and sequenced. This insertion element has a nucleotide sequence of 1472 bp, with one open reading frame (ORF1), whi
Fatal B-cell lymphoproliferative syndrome in allogeneic marrow graft recipients. A clinical, immunobiological and pathological study.: Virchows Arch B Cell Pathol Incl Mol Pathol. 1991;60(5):307-19. Unique Identifier : AIDSLINE MED/92116494; Simon M; Bartram CR; Friedrich W; Arnold R; Schmeiser T; Hampl W; Muller-Hermelink HK; Heymer B; Department of Pathology, University of Ulm, Federal Republic of; Germany.; We have studied four cases of fatal B-cell lymphoproliferative syndrome (LPS) developing among 333 patients (incidence 1.2%) treated with allogeneic bone marrow transplantation (BMT). All four patients had received a T-cell depleted graft. Onset of the first clinical symptoms (palpable lymph node enlargement in three
HIV-1 binding to CD4 T cells does not induce a Ca2+ influx or lead to activation of protein kinases.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):587-93. Unique Identifier : AIDSLINE MED/92118455; Orloff GM; Kennedy MS; Dawson C; McDougal JS; Division of Immunologic, Oncologic and Hematologic Diseases,; Centers for Disease Control, U.S. Department of Health and Human; Services, Atlanta, GA 30333.; The penetration of CD4+ cells by human immunodeficiency virus (HIV) involves a high affinity interaction between the viral attachment protein, gp120, and the cellular receptor, CD4. The mechanism by which the virus penetrates the host cell subsequent to viral binding is unknown. We have investigated the possibility th
[Effect of alfa-2b interferon on prognostic parameters and clinical events in HIV positive patients in the LAS/ARC stage]: Med Klin. 1991 Nov 15;86(11):555-60, 606. Unique Identifier : AIDSLINE MED/92123014; Plettenberg A; Nilsson M; Bahlmann W; Franke C; Stoehr A; Arndt R; Baumann B; Laufs R; Meigel W; Abteilungen fur Allgemeines Krankenhaus St. Georg, Hamburg.; A number of in vivo and in vitro results suggest that interferons have an antiretroviral effect on HIV. To check this, 15 HIV-positive patients who had no full-blown AIDS, were treated with recombinant interferon alpha 2b (5 mill. IU s. c. three times a week) over a period of six months. Twelve to 16 weeks after the i
A mathematical model of vaccination against HIV to prevent the development of AIDS.: Proc R Soc Lond B Biol Sci. 1991 Nov 22;246(1316):141-6. Unique Identifier : AIDSLINE MED/92123720; Nowak MA; McLean AR; Department of Zoology, University of Oxford, U.K.; Vaccination and post-exposure immunization against the human immunodeficiency viruses (HIV-1 and HIV-2) faces the problem of the extensive genetic and antigenic variability of these viruses. This raises the question of what fraction of all possible antigen strains of the virus must be recognized by the immune response
Quinolinic acid and kynurenic acid in the mammalian brain.: Adv Exp Med Biol. 1991;294:185-99. Unique Identifier : AIDSLINE MED/92125148; Schwarcz R; Du F; Maryland Psychiatric Research Center, Baltimore 21228.
Management of anorexia-cachexia associated with cancer and HIV infection.: Oncology (Huntingt). 1991 Sep;5(9 Suppl):13-7. Unique Identifier : AIDSLINE MED/92088881; Gorter R; Division of AIDS Oncology, University of California School of; Medicine, San Francisco.; The cachexia associated with cancer and AIDS appears to result from a number of processes, most of which impair caloric intake. Although past attempts to reverse anorexia-cachexia have generally been disappointing, several promising new pharmacologic approaches are currently being evaluated, including megestrol acetatf
An overview of palliative care in cancer and AIDS.: Oncology (Huntingt). 1991 Sep;5(9 Suppl):7-11. Unique Identifier : AIDSLINE MED/92088884; Walsh TD; Department of Hematology/Oncology, Cleveland Clinic Foundation.; Many patients with cancer or AIDS present with pain and multiple other physical and psychological symptoms. For patients with advanced cancer or AIDS, the symptoms are truly the disease and should be the basis for the therapeutic plan. This requires maintaining an active problemsolving approach, giving particular attef
Protein-protein interactions of HIV-1 reverse transcriptase: implication of central and C-terminal regions in subunit binding.: Biochemistry. 1991 Dec 17;30(50):11707-19. Unique Identifier : AIDSLINE MED/92089078; Becerra SP; Kumar A; Lewis MS; Widen SG; Abbotts J; Karawya EM; Hughes SH; Shiloach J; Wilson SH; Lewis MS; Laboratory of Biochemistry, National Cancer Institute, National; Institutes of Health, Bethesda, Maryland 20892.; Human immunodeficiency virus 1 reverse transcriptase (RT) purified from virions is composed of a approximately 51,000 Mr polypeptide and a approximately 66,000 Mr polypeptide that are thought to be in heterodimer structure (Chandra et al., 1986; Hansen et al., 1988; Starnes & Cheng, 1989) and are identical except f
Metabolic and structural effects of HIV infection in human peripheral blood mononuclear cells can be monitored with 1H NMR spectroscopy.: J Acquir Immune Defic Syndr. 1991;4(11):1073-81. Unique Identifier : AIDSLINE MED/92092168; Federico M; Maggiorella MT; Sulli N; Guidoni L; Luciani AM; Rosi A; Viti V; Rossi GB; Verani P; Laboratory of Virology, Istituto Superiore di Sanita, Rome,; Italy.; Infection of human peripheral blood lymphocytes by human immunodeficiency virus type 1 (HIV-1) was investigated by means of 1H nuclear magnetic resonance spectroscopy, taking advantage of the presence of signals from fluid lipid domains in the membrane of stimulated lymphocytes. A transient decrease of the lipid methy
[The treatment of large-cell non-Hodgkin's lymphomas with the MACOP-B protocol]: Med Clin (Barc). 1991 Oct 26;97(14):521-5. Unique Identifier : AIDSLINE MED/92092805; Montalban C; Rodriguez Garcia JL; Marcos Robles J; Serrano M; Arechaga S; Perales J; Bellas C; Servicio de Medicina Interna, Hospital Ramon y Cajal, Madrid.; BACKGROUND: To investigate the results of the treatment of large-cell non-Hodgkin s lymphomas (LCNHL) with the MACOP-B chemotherapy protocol. METHODS: 20 patients with the following inclusion criteria were treated: LCNHL with a definite majority of large lymphoid cells and absence of previous therapy, HIV infection or
[Reverse transcriptase of the human immunodeficiency virus: cloning, expression in Escherichia coli, purification of the enzyme, and production of monoclonal antibodies]: Mol Biol (Mosk). 1991 Sep-Oct;25(5):1248-57. Unique Identifier : AIDSLINE MED/92092979; Rechinskii VO; Barbashov SF; Degtiarev IL; Vorob'ev SM; Liakhov DL; Kostiuk DA; Starov AI; Matsevich GR; Kochetkov SN; To express HIV-1 reverse transcriptase in E. coli a number of genetic constructions containing reverse transcriptase and virus protease nucleotide sequences was obtained. The products of expression were characterized; monoclonal antibodies to reverse transcriptase were produced. The purification of reverse transcripta
CD4-gp120 interactions.: Curr Opin Immunol. 1991 Aug;3(4):552-8. Unique Identifier : AIDSLINE MED/92096151; McDougal JS; Klatzmann DR; Maddon PJ; Centers for Disease Control, Atlanta, Georgia.; The three-dimensional structure of the binding domain of the CD4 molecule has been determined and extensive mutational analyses of the respective binding sites on gp120 and CD4 have been completed. The consequences of gp120-CD4 binding with respect to secondary changes in the virion, or the cell, that may be required
Acquired immunodeficiency syndrome (AIDS)--data as at 1 October 1991.: Wkly Epidemiol Rec. 1991 Oct 4;66(40):289-90. Unique Identifier : AIDSLINE MED/92096358
T cell responses to peptides covering the gag p24 region of HIV-1 occur in HIV-1 seronegative individuals.: Int Immunol. 1991 Oct;3(10):939-47. Unique Identifier : AIDSLINE MED/92096413; Vyakarnam A; Matear PM; Cranenburg C; Michie C; Beverley PC; Wahren B; Gill SK; Weller I; Academic Department of Genito-Urinary Medicine, University; College London, UK.; We demonstrate that peptides (16 amino acids long) covering the sequence of the HIV-1 core protein p24 induce significant proliferation in peripheral blood mononuclear cells (PBMC) of several (greater than 50%) healthy seronegative volunteers as well as seronegative homosexual men. The nature of this response was char
A transposition of the reverse transcriptase gene reveals unexpected structural homology to E. coli DNA polymerase I.: Genetica. 1991;84(2):77-86. Unique Identifier : AIDSLINE MED/92097932; Taylor EW; Jaakkola J; Department of Medicinal Chemistry, College of Pharmacy,; University of Georgia, Athens 30602.; The rational design of antiviral agents targeting the reverse transcriptase (RT) of the human immunodeficiency virus (HIV) would greatly benefit from a more intimate knowledge of the structure of RT. Until now, the degree of sequence similarity between RT and E. coli DNA polymerase I (Pol I) has been thought to be con
Analysis of prognostic factors in thymectomized patients with myasthenia gravis: correlation between thymic lymphoid cell subsets and postoperative clinical course.: J Neurol Sci. 1991 Oct;105(2):143-9. Unique Identifier : AIDSLINE MED/92099080; Fujii N; Itoyama Y; Machi M; Goto I; Department of Neurology, Faculty of Medicine, Kyushu University,; Fukuoka, Japan.; We retrospectively examined the postoperative clinical course of 50 consecutive patients with myasthenia gravis who underwent a transsternal extended thymectomy. Twenty-six patients (52%) showed a steady improving postoperative course without any additional immunotherapy (group A). The remaining 24 patients (48%) had
[Pulmonary Kaposi's sarcoma in a heterosexual parenteral drug addict patient with the acquired immunodeficiency syndrome]: Med Clin (Barc). 1991 Oct 19;97(13):500-2. Unique Identifier : AIDSLINE MED/92099681; Grocin AI; Goya MA; Arrizabalaga J; Iribarren JA; Rodriguez-Arrondo F; Tuneu A; Lobo C; Unidad de Enfermedades Infecciosas, Hospital Nuestra Senora de; Aranzazu, San Sebastian.; A case of Kaposi syndrome is described in a 28-year-old heterosexual male with acquired immunodeficiency syndrome. The disease began clinically with pulmonary disease, without mucocutaneous lesions. This form of presentation is extremely infrequent and has not been described in non-homosexual subjects. Clinical manife
[Cytomegalovirus ileocolitis in patients with HIV infection is a treatable cause of severe abdominal problems]: Lakartidningen. 1991 Dec 4;88(49):4249-50. Unique Identifier : AIDSLINE MED/92099710; Soderlund C; Bratt G; Grutzmeier S; Rieger A; Sandstrom E; Sjunnesson M; Kirurgiska kliniken, Samtliga vid Sodersjukhuset, Stockholm.
Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine.: Antimicrob Agents Chemother. 1991 Oct;35(10):2003-11. Unique Identifier : AIDSLINE MED/92102174; Kong XB; Zhu QY; Ruprecht RM; Watanabe KA; Zeidler JM; Gold JW; Polsky B; Armstrong D; Chou TC; Laboratory of Biochemical Pharmacology, Memorial Sloan-Kettering; Cancer Center, New York, New York 10021.; The effects of 3 -azido-3 -deoxythymidine ( AZT ), phosphonoformate (PFA), and 2 ,3 -dideoxythymidine (ddT) and their combination on human immunodeficiency type 1 (HIV-1) replication were studied by measuring the HIV-1 p24 antigen expression and reverse
Cytokine enhancement of simian immunodeficiency virus (SIV/mac) from a chronically infected cloned T-cell line (HuT-78).: Arch Virol. 1991;121(1-4):43-53. Unique Identifier : AIDSLINE MED/92102354; Lairmore MD; Post AA; Goldsmith CS; Folks TM; Division of Viral and Rickettsial Diseases, Centers for Disease; Control, Atlanta, Georgia.; Simian immunodeficiency viruses (SIV) are a family of primate lentiviruses similar to human immunodeficiency viruses (HIV) in their genetic sequence and pathogenesis. However, host-derived cofactors which may determine the extent of viral replication are not clearly defined for SIV or HIV infections. A HuT-78 cell lin
Anti-idiotypic antibodies against anti-CD4 antibodies MT151 and OKT4A.: Viral Immunol. 1991 Summer;4(2):83-90. Unique Identifier : AIDSLINE MED/92102545; Liang SH; Rieber P; Prewett M; Riethmuller G; Pletcher C; Hoxie J; Koprowski H; Herlyn D; Wistar Institute, Philadelphia, Pennsylvania.; Anti-idiotypic antibodies (Ab2) binding to the antigen-combining site of other antibodies may functionally and even structurally mimic antigen. Ab2 to antibodies directed against the lymphocyte CD4 receptor for human immunodeficiency virus type 1 (HIV-1) may mimic the receptor and therefore inhibit viral infectivity.
Quantification of alphafetoprotein (AFP) endocytosis by PHA-activated peripheral blood mononuclear cells (PBMC) from HIV-infected individuals. A useful test of predictive value for the progression of AIDS.: Microbiologia. 1991 Sep;7(2):98-105. Unique Identifier : AIDSLINE MED/92102616; Aguilar JJ; Macho A; Semmel M; Uriel J; Laboratoire de Chimie des Proteines, Institut de Recherches; Scientifiques sur le Cancer (CNRS), Villejuif, France.; Serum alphafetoprotein (AFP) is actively taken up, through receptor-mediated endocytosis, by many embryo-fetal cells during ontogenic development but also by neoplastic cells, as well as by normal peripheral T lymphocytes after mitogenic activation. We have previously shown that the ability to internalize AFP is impai
The DNA-dependent and RNA-dependent DNA polymerase activities of the reverse transcriptases of human immunodeficiency viruses types 1 and 2.: AIDS Res Hum Retroviruses. 1991 Nov;7(11):883-8. Unique Identifier : AIDSLINE MED/92102764; Shaharabany M; Hizi A; Department of Cell Biology and Histology, Sackler School of; Medicine, Tel Aviv University, Israel.; We have constructed a series of plasmids which, when introduced into Escherichia coli, induce the overexpression of soluble wild-type and mutated forms of the reverse transcriptases (RTs) from human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2, respectively). These proteins were analyzed previously for thei
Human immunodeficiency virus reverse transcriptase displays a partially processive 3' to 5' endonuclease activity.: J Biol Chem. 1991 Dec 25;266(36):24295-301. Unique Identifier : AIDSLINE MED/92105079; DeStefano JJ; Buiser RG; Mallaber LM; Bambara RA; Fay PJ; Department of Biochemistry, University of Rochester, New York; 14642.; We have examined the ribonuclease H (RNase H) activity of human immunodeficiency virus reverse transcriptase (HIV-RT) using a natural sequence 83-nucleotide-long RNA template to which was hybridized a DNA oligomer. This substrate configuration allowed for the simultaneous electrophoretic resolution of 5 -, 3 -, and in
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture.: Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11241-5. Unique Identifier : AIDSLINE MED/92107925; Richman D; Shih CK; Lowy I; Rose J; Prodanovich P; Goff S; Griffin J; Department of Pathology, University of California, San Diego.; We have recently described a nonnucleoside compound that specifically inhibits the reverse transcriptase of human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS. This compound, nevirapine (BI-RG-587), interacts with highly conserve
An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein.: Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11276-80. Unique Identifier : AIDSLINE MED/92107932; Tsomides TJ; Walker BD; Eisen HN; Department of Biology, Massachusetts Institute of Technology,; Cambridge 02139.; CD8+ cytotoxic T lymphocytes recognize cell surface complexes formed by class I major histocompatibility complex (MHC-I) glycoproteins and antigenic peptides. We have identified a peptide nonamer (termed IV9) derived from the human immunodeficiency virus that is over a millionfold more active (at subpicomolar concentr
Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase.: Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11363-7. Unique Identifier : AIDSLINE MED/92107950; Prasad VR; Lowy I; de los Santos T; Chiang L; Goff SP; Department of Microbiology and Immunology, Albert Einstein; College of Medicine, Bronx, NY 10461.; The appearance of drug-resistant strains of viral pathogens is a major difficulty confounding current efforts to block viral infections. The identification and analysis of mutations responsible for drug resistance can provide important clues helpful in understanding the mechanisms of resistance and in the eventual dev
[Combination therapies with anti-retroviral agents in HIV and AIDS infections (editorial)]: Rev Clin Esp. 1991 Oct;189(6):253-5. Unique Identifier : AIDSLINE MED/92108265; Fernandez-Cruz E
Constitutive expression of c-jun and jun-B in cell lines infected with human T-lymphotropic virus types I and II.: Biochem Biophys Res Commun. 1991 Dec 31;181(3):976-80. Unique Identifier : AIDSLINE MED/92109789; Hooper WC; Rudolph DL; Lairmore MD; Lal RB; Hematologic Diseases Branch, National Center for Infectious; Diseases, Centers for Disease Control, Public Health Service,; U.S. Department of Health and Human Services, Atlanta, Georgia; 30333.; To better understand the transcriptional regulation of human T-lymphotropic viruses, expression of the nuclear proto-oncogenes, jun-B and c-jun were examined in cell lines infected with HTLV-I/II. Constitutive high levels of jun-B and c-jun expression were observed in HTLV-I (MT-2, Hut-102, IR, FS, SP) and HTLV-II inf
Idiotypic cascades associated with the CD4-HIV gp120 interaction: principles for idiotype-based vaccines.: Int Rev Immunol. 1990;7(1):109-19. Unique Identifier : AIDSLINE MED/92113414; Attanasio R; Kennedy RC; Department of Virology and Immunology, Southwest Foundation for; Biomedical Research, San Antonio, Texas.; Idiotypes (Id) are antigenic determinants expressed on the variable (V) region of the immunoglobulin molecule. Id-bearing antibodies, or Ab-1, are produced upon stimulation with a given antigen. Ab-1 may elicit the production of anti-idiotypic antibodies (anti-Id) or Ab-2. The anti-Id also expresses Id determinants an
HIV-neutralizing antibodies: epitope identification and significance for future vaccine.: Int Rev Immunol. 1990;7(1):15-30. Unique Identifier : AIDSLINE MED/92113415; Robert-Guroff M; National Institutes of Health, National Cancer Institute,; Laboratory of Tumor Cell Biology, Bethesda, Maryland 20892.
Peptide component vaccine engineering: targeting the AIDS virus.: Int Rev Immunol. 1990;7(1):85-107. Unique Identifier : AIDSLINE MED/92113420; Cease KB; Department of Internal Medicine, University of Michigan, Ann; Arbor 48109-0724.; Most of the successful vaccines developed to date induce protective immunity resembling that produced by natural infection. HIV infection does not induce protective immunity. Thus, previously successful approaches based on live- or killed-virus preparations may not yield an effective and safe AIDS vaccine and many fee
Bovine immunodeficiency virus: immunochemical characterization and serological survey.: J Gen Virol. 1991 Dec;72 ( Pt 12):2923-8. Unique Identifier : AIDSLINE MED/92113533; Horzinek M; Keldermans L; Stuurman T; Black J; Herrewegh A; Sillekens P; Koolen M; Department of Virology, Veterinary Faculty, State University of; Utrecht, The Netherlands.; Bovine immunodeficiency virus (BIV) was purified by isodensity centrifugation; viral activities were monitored in gradient fractions using the reverse transcriptase assay and a p26-specific monoclonal antibody ELISA. In the coincident peak fractions (density about 1.17 g/ml) proteins with Mr values of 26K, 17K, 53K, 1
[AIDS in the world]: Minerva Chir. 1991 Oct 31;46(20):1151-2. Unique Identifier : AIDSLINE MED/92115131; Di Nola
Antibody-dependent cell-mediated cytotoxicity directed by a human monoclonal antibody reactive with gp120 of HIV-1.: AIDS. 1991 Nov;5(11):1309-14. Unique Identifier : AIDSLINE MED/92118257; Koup RA; Robinson JE; Nguyen QV; Pikora CA; Blais B; Roskey A; Panicali D; Sullivan JL; Department of Pediatrics, University of Massachusetts Medical; School, Worcester.; We used a human monoclonal antibody (MAb; 15e) to identify an antibody-dependent cell-mediated cytotoxicity (ADCC) epitope on HIV-1 gp120. 15e has been shown to recognize a conformation-dependent epitope on gp120 which is important in both CD4 binding and neutralizing of HIV-1 infection. 15e binds to gp120 of HIV-1III
Similarities of viral proteins to toxins that interact with monovalent cation channels [editorial]: AIDS. 1991 Nov;5(11):1381-4. Unique Identifier : AIDSLINE MED/92118270; Garry RF; Kort JJ; Koch-Nolte F; Koch G
Chemoattractant(s) in culture supernatants of HTLV-I-Infected T-cell lines.: AIDS Res Hum Retroviruses. 1991 Jul;7(7):571-7. Unique Identifier : AIDSLINE MED/92118453; Saggioro D; Wang JM; Sironi M; Luini W; Mantovani A; Chieco-Bianchi L; Istituto di Oncologia, Centro Interuniversitario per la Ricerca; sul Cancro (C.I.R.C.), I.S.T., Padova, Italy.; Supernatants obtained from four HTLV-I transformed cell lines (MT2, MT4, C91/PL, and 81-66/45) induced in vitro migration of monocytes, polymorphonuclear leukocytes (PMN), and lymphocytes. The MT2, C91/PL, and 81-66/45 cell lines expressed both lymphotoxin (LT) and tumor necrosis factor (TNF-alpha) mRNA transcripts, a
A leucine zipper-like motif may mediate HIV reverse transcriptase subunit binding [letter]: New Biol. 1991 Oct;3(10):1015-9. Unique Identifier : AIDSLINE MED/92118707; Baillon JG; Nashed NT; Kumar A; Wilson SH; Jerina DM
Prospects for the use of synthetic antigens in immunodiagnosis.: Biomed Sci. 1990;1(6):553-64. Unique Identifier : AIDSLINE MED/92119040; Khaitov RM; Andreev SM; Institute of Immunology, Ministry of Health of the USSR, Moscow.; Methods for the localization and prediction of protein antigenic determinants are described, and the diagnostic potential of synthetic peptide antigens in cases of HIV, hepatitis B, and influenza is demonstrated. Attention is concentrated on the principles governing the creation and application of artificial diagnosti
RNA-mediated transfer of cellular immunity to a synthetic env antigen of the human immunodeficiency virus (HIV-1).: Mol Cell Biochem. 1991 Nov 13;108(1):1-8. Unique Identifier : AIDSLINE MED/92123160; Passos Junior GA; de Lucca FL; Dept. of Morphology, School of Dentistry of Ribeirao Preto,; University of Sao Paulo, Brasil.; A sheep was immunized with a synthetic peptide corresponding to amino acid residues 586-606 of the precursor envelope protein GP-160 of the HIV-1 including a conserved epitope region of the GP-41 transmembrane protein in the mature viral particles, referred to as SM 284 HIV-1 [1]. It is demonstrated that immune RNA ex
Zidovudine and other reverse transcriptase inhibitors in the management of human immunodeficiency virus-related disease.: Pharmacotherapy. 1991;11(6):419-48; discussion 448-9. Unique Identifier : AIDSLINE MED/92123686; Matthews SJ; Cersosimo RJ; Spivack ML; Department of Pharmacy Practice, College of Pharmacy/AHP,; Northeastern University, Boston, Massachusetts.; Licensed in 1987, zidovudine remains the only medication with proved efficacy for the treatment of disease caused by the human immunodeficiency virus (HIV). New information on the pharmacology (adults and children), effects of kidney and liver dysfunction on the disposition of the drug, and drug-drug interactions have
Differential HIV replication and HIV-induced interferon production in mononuclear phagocytes: relationship to cell maturation.: Res Virol. 1991 Sep-Oct;142(5):353-61. Unique Identifier : AIDSLINE MED/92124002; Mosborg-Petersen P; Toth FD; Zachar V; Villadsen JA; Norskov-Lauritsen N; Aboagye-Mathiesen G; Chermann JC; Ebbesen P; Department of Virus and Cancer, Danish Cancer Society, Aarhus,; Denmark.; We have investigated the replication of human immunodeficiency virus (HIV) and HIV-induced interferon (IFN) production in human mononuclear phagocytes at 2 different stages of in vitro maturation. Blood monocytes and monocyte-derived macrophages from 6 healthy, HIV-seronegative donors were challenged with HIV1IIIB and
Inhibition of human immunodeficiency virus replication in a human T cell line by antisense RNA expressed in the cell.: Virus Genes. 1991 Jul;5(3):189-202. Unique Identifier : AIDSLINE MED/92124760; Gyotoku J; el-Farrash MA; Fujimoto S; Germeraad WT; Watanabe Y; Teshigawara K; Harada S; Katsura Y; Department of Immunology, Kyoto University, Japan.; The effect of the expression of antisense RNA against the human immunodeficiency virus (HIV) genome in a human T-cell line CEM on HIV replication was investigated. A 2.7 kilobase (kb) fragment of the HIV genome, including tat and a part of rev and env, was cloned into the retroviral vector WB in the antisense orientat
Implications of interferon-induced tryptophan catabolism in cancer, auto-immune diseases and AIDS.: Adv Exp Med Biol. 1991;294:425-35. Unique Identifier : AIDSLINE MED/92125173; Brown RR; Ozaki Y; Datta SP; Borden EC; Sondel PM; Malone DG; Department of Human Oncology, University of Wisconsin Medical; School, Madison 53792.; Tryptophan (Trp) is an indispensable amino acid required for biosynthesis of proteins, serotonin and niacin. Indoleamine 2,3-dioxygenase (IDO) is induced by infections, viruses, lipopolysaccharides, or interferons (IFNs) and this results in significant catabolism of Trp along the kynurenine (Kyn) pathway. Intracellula
Heterogeneity of the CD8 lymphocytes in healthy and HIV 1 infected subjects.: Allergol Immunopathol (Madr). 1991 Mar-Apr;19(2):79-84. Unique Identifier : AIDSLINE MED/92125250; Arras M; Contu L; Cattedra di Genetica Medica, Universita di Cagliari.; CD8 lymphocytes have been subdivided on the basis of Leu2 antigen cell surface density and coexpression of Leu4 and Leu11 antigens in two categories: Leu2bright and Leu2dim. Some CD8 lymphocyte phenotypes present in small percentages in some subjects do not come under these subsets. Flow cytometry analysis moreover sh
Human T-cell leukemia virus type I associated lymphadenitis.: Cancer. 1992 Jan 1;69(1):239-48. Unique Identifier : AIDSLINE MED/92089849; Ohshima K; Kikuchi M; Masuda Y; Sumiyoshi Y; Eguchi F; Mohtai H; Takeshita M; Kimura N; Department of Pathology, School of Medicine, Fukuoka University,; Japan.; Histopathologic changes in lymph nodes were examined from ten patients with mild lymphadenopathy, a few atypical lymphocytes in their peripheral blood, skin lesions, and proviral DNA of human T-cell leukemia virus type I (HTLV-I) in their nodes. The proviral DNA of HTLV-I was detected by southern blot analysis, in sit
Quantitative analysis of human immunodeficiency virus type 1 antibody reactivity by western immunoblots: evaluation of relative antibody levels in seropositive individuals and mothers.: J Infect Dis. 1992 Jan;165(1):111-8. Unique Identifier : AIDSLINE MED/92091857; Geffin RB; Lai SH; Hutto C; Scott GB; Scott WA; Master M; Parks WP; Department of Pediatrics, University of Miami, School of; Medicine, FL 33136.; A quantitative analysis of antibody responses to human immunodeficiency virus type 1 (HIV-1) proteins using Western immunoblots and 125I-labeled protein A is reproducible and can be validated. The antibody levels obtained by Western immunoblots were compared with stoichiometric p24 radioimmunoassay over a wide range o
Nonspecific proctitis: association with human immunodeficiency virus infection in homosexual men [see comments]: J Infect Dis. 1992 Jan;165(1):150-4. Unique Identifier : AIDSLINE MED/92091865; Law CL; Qassim M; Cunningham AL; Mulhall B; Grierson JM; Sexually Transmissible Diseases Centre, Sydney Hospital,; Australia.; In a cross-sectional study of 140 homosexual men attending a sexually transmissible diseases clinic, the association between the presence of antibody to the human immunodeficiency virus (HIV) and the presence of proctitis, as determined by histologic examination, as well as part or present exposure to other pathogens
Are strains of Mycobacterium avium more drug resistant when isolated from human immunodeficiency virus-infected patients? [letter; comment]: J Infect Dis. 1992 Jan;165(1):179-80. Unique Identifier : AIDSLINE MED/92091872; Hoffner SE
An animal model of Mycobacterium avium complex disseminated infection after colonization of the intestinal tract.: J Infect Dis. 1992 Jan;165(1):75-9. Unique Identifier : AIDSLINE MED/92091886; Bermudez LE; Petrofsky M; Kolonoski P; Young LS; Kuzell Institute for Arthritis and Infectious Diseases, Medical; Research Institute of San Francisco at California Pacific Medical; Center 94115.; Mycobacterium avium complex infections occur in 30%-80% of patients with AIDS. Recent evidence supports the gastrointestinal tract as the source of M. avium. Although a reproducible animal model exists, a model more closely resembling the infection in AIDS patients is needed to answer pertinent questions regarding res
Concurrent human immunodeficiency virus and mycobacterial infection of macrophages in vitro does not reveal any reciprocal effect.: J Infect Dis. 1992 Jan;165(1):80-6. Unique Identifier : AIDSLINE MED/92091887; Meylan PR; Munis JR; Richman DD; Kornbluth RS; Department of Medicine, University of California, San Diego,; School of Medicine.; To test whether in vitro infection of macrophages with either human immunodeficiency virus (HIV) or mycobacteria would influence the replication of the other pathogen, macrophages were infected sequentially with the macrophage-tropic isolate HTLV-IIIBa-L/85 and Mycobacterium tuberculosis H37Rv or Mycobacterium avium.
Prevalence of human immunodeficiency virus infection among patients attending tuberculosis clinics in the United States.: J Infect Dis. 1992 Jan;165(1):87-92. Unique Identifier : AIDSLINE MED/92091888; Onorato IM; McCray E; Division of HIV/AIDS, Centers for Disease Control, Atlanta, GA; 30333.; In 1988-1989, surveillance for human immunodeficiency virus (HIV) infection was conducted in 20 clinics providing medical care for patients with suspected and confirmed tuberculosis (TB) in 14 cities. A total of 3077 specimens from consecutive patients were tested for HIV after patient identifiers were removed. The me
Clinical pharmacology of 2',3'-dideoxyinosine in human immunodeficiency virus-infected children.: J Infect Dis. 1992 Jan;165(1):99-104. Unique Identifier : AIDSLINE MED/92091890; Balis FM; Pizzo PA; Butler KM; Hawkins ME; Brouwers P; Husson RN; Jacobsen F; Blaney SM; Gress J; Jarosinski P; et al; Pediatric Branch, National Cancer Institute, National Institutes; of Health, Bethesda, MD 20892.; The pharmacokinetics of intravenous and oral 2 ,3 -dideoxyinosine (ddI) and the relationships between pharmacokinetic parameters and measures of response were studied in 48 human immunodeficiency virus-infected children. Disappearance of ddI from plasma after the intravenous dose was rapid and biexponential, with half
Prevalence of tuberculin positivity and skin test anergy in HIV-1-seropositive and -seronegative intravenous drug users [see comments]: JAMA. 1992 Jan 15;267(3):369-73. Unique Identifier : AIDSLINE MED/92092276; Graham NM; Nelson KE; Solomon L; Bonds M; Rizzo RT; Scavotto J; Astemborski J; Vlahov D; Department of Epidemiology, Johns Hopkins Univesity School of; Hygiene and Public Health, Baltimore, MD 21205.; OBJECTIVES.--To identify differences in purified protein derivative (PPD) tuberculin positivity and skin test anergy rates by human immunodeficiency virus (HIV) serostatus, CD4+ lymphocyte count, and other risk factors in intravenous drug users (IVDUs); and to evaluate the appropriateness of the Centers for Disease Co
Tuberculin skin testing and the HIV epidemic [editorial; comment]: JAMA. 1992 Jan 15;267(3):409-10. Unique Identifier : AIDSLINE MED/92092285; Huebner RE; Villarino ME; Snider DE Jr
Sexual behavior among high school students--United States, 1990.: MMWR Morb Mortal Wkly Rep. 1992 Jan 3;40(51-52):885-8. Unique Identifier : AIDSLINE MED/92092945; Since the 1970s, sexually transmitted diseases (STDs) (including human immunodeficiency virus infection and acquired immunodeficiency syndrome), unintended pregnancies, and other problems that result from sexual activity have increased among adolescents in the United States . For exampl
Epidemiology of transfusion-associated acquired immunodeficiency syndrome in children in the United States, 1981 through 1989.: Pediatrics. 1992 Jan;89(1):123-7. Unique Identifier : AIDSLINE MED/92093463; Jones DS; Byers RH; Bush TJ; Oxtoby MJ; Rogers MF; Division of HIV/AIDS, Centers for Disease Control, Atlanta, GA; 30333.; From 1981 through 1989, 212 cases of transfusion-associated (TA) acquired immunodeficiency syndrome (AIDS) were reported to the Centers for Disease Control. In a study of the epidemiology of pediatric TA AIDS, this group was compared with perinatally acquired (PA) and adult TA AIDS cases. The number of pediatric TA AI
Chest manifestations of AIDS.: Am Fam Physician. 1992 Jan;45(1):163-8. Unique Identifier : AIDSLINE MED/92095233; Poulton TB; Aultman Hospital, Canton, Ohio.; Chest radiographs, computed tomography and gallium scanning are useful in diagnosing the pulmonary manifestations of acquired immunodeficiency syndrome. Most opportunistic infections in patients with AIDS affect the lung as the primary target organ. Bilateral perihilar or basilar interstitial infiltrates, which may pr
Retinal toxicity in human immunodeficiency virus-infected children treated with 2',3'-dideoxyinosine.: Am J Ophthalmol. 1992 Jan 15;113(1):1-7. Unique Identifier : AIDSLINE MED/92095332; Whitcup SM; Butler KM; Caruso R; de Smet MD; Rubin B; Husson RN; Lopez JS; Belfort R Jr; Pizzo PA; Nussenblatt RB; Laboratory of Immunology, National Eye Institute, National; Institutes of Health, Bethesda, MD 20892.; To assess the safety and antiretroviral activity of 2 ,3 -dideoxyinosine, we enrolled 43 children with symptomatic (Centers for Disease Control class P-2) human immunodeficiency virus infection in a Phase I-II study and monitored them prospectively for the development of ocular complications secondary to HIV infection
Visual dysfunction without retinitis in patients with acquired immunodeficiency syndrome.: Am J Ophthalmol. 1992 Jan 15;113(1):8-13. Unique Identifier : AIDSLINE MED/92095356; Quiceno JI; Capparelli E; Sadun AA; Munguia D; Grant I; Listhaus A; Crapotta J; Lambert B; Freeman WR; Department of Ophthalmology, University of California, San Diego.; Patients with human immunodeficiency virus infection may have noninfectious and infectious retinopathies, as well as clinical symptoms consistent with optic nerve dysfunction. Noninfectious acquired immunodeficiency syndrome-related retinopathy is seen in most patients with AIDS. Morphologic studies have shown that th
Pharmacotherapy and psychotherapy for major depression in a man with AIDS [letter]: Am J Psychiatry. 1992 Jan;149(1):138. Unique Identifier : AIDSLINE MED/92095379; Sullivan PF; Carra J; Musgrave J; Rabinowitz J; Cornes C; Johnson D
A prospective controlled study of magnetic resonance imaging of the brain in gay men and parenteral drug users with human immunodeficiency virus infection.: Arch Neurol. 1992 Jan;49(1):38-43. Unique Identifier : AIDSLINE MED/92095802; Dooneief G; Bello J; Todak G; Mun IK; Marder K; Malouf R; Gorman J; Hilal S; Stern Y; Mayeux R; HIV Center for Clinical and Behavioral Studies, New York State; Psychiatric Institute.; To detect the earliest structural changes in the brain in human immunodeficiency virus (HIV) infection, 118 gay men and 115 parenteral drug users enrolled in a study of the natural history of HIV infection underwent magnetic resonance imaging evaluations. Routine T2-weighted and heavily T2-weighted scans for quantific
Increased adherence of T cells to human endothelial cells in patients with human T-cell lymphotropic virus type I-associated myelopathy.: Arch Neurol. 1992 Jan;49(1):74-6. Unique Identifier : AIDSLINE MED/92095807; Ichinose K; Nakamura T; Kawakami A; Eguchi K; Nagasato K; Shibayama K; Tsujihata M; Nagataki S; First Department of Internal Medicine, Nagasaki University School; of Medicine, Japan.; We investigated the adherence of T cells to human umbilical vein endothelial cells in seven patients with human T-lymphotropic virus type I (HTLV-I)-associated myelopathy. The adherence of T cells to endothelial cells increased significantly in all the patients with HTLV-I-associated myelopathy when compared with the
Analysis and perspective from the infectious disease department.: Arch Otolaryngol Head Neck Surg. 1992 Jan;118(1):19-20. Unique Identifier : AIDSLINE MED/92096209; Pollard RB
Human immunodeficiency virus-associated Hodgkin's disease [letter; comment]: Cancer. 1992 Jan 15;69(2):601. Unique Identifier : AIDSLINE MED/92097003; Delabie J; De Wolf-Peeters C
AIDS: legal implications for managers.: J Am Diet Assoc. 1992 Jan;92(1):74-7. Unique Identifier : AIDSLINE MED/92098909; Cross EW; School of Human Ecology, Louisiana State University Baton Rouge; 70803-4301.; As the incidence of acquired immunodeficiency syndrome (AIDS) escalates, its consequences increasingly will affect the workplace. Dietitians with management responsibilities will be called upon to make decisions concerning the rights of both employees and clients or patrons. They must be knowledgeable about AIDS-relat
Stimulation of cutaneous T-cell lymphoma cells with superantigenic staphylococcal toxins.: J Invest Dermatol. 1992 Jan;98(1):33-7. Unique Identifier : AIDSLINE MED/92098975; Tokura Y; Heald PW; Yan SL; Edelson RL; Department of Dermatology, Yale University School of Medicine,; New Haven, CT 06510.; Stimulation of T cells by superantigenic bacterial toxins is selective for cells bearing particular B chain variable (VB) gene segments of T-cell receptor (TCR). In humans, staphylococcal exfoliating toxin (ExT) and toxic shock syndrome toxin-1 (TSST-1) are known to stimulate VB 2-bearing T cells and staphylococcal en
The second 100,000 cases of acquired immunodeficiency syndrome--United States, June 1981-December 1991.: MMWR Morb Mortal Wkly Rep. 1992 Jan 17;41(2):28-9. Unique Identifier : AIDSLINE MED/92100045; The first cases of acquired immunodeficiency syndrome (AIDS) were reported in June 1981. From 1981 through December 1987, 50,000 AIDS cases had been reported to CDC, and by August 1989, 100,000 cases had been reported. From September 1989 through November 1991, state and territorial health departments reported 100,000
Vaccination with gp160 in HIV [letter; comment]: N Engl J Med. 1992 Jan 30;326(5):347; discussion 348. Unique Identifier : AIDSLINE MED/92100158; Oyaizu N; Chirmule N; Pahwa S
Vaccination with gp160 in HIV [letter; comment]: N Engl J Med. 1992 Jan 30;326(5):347-8. Unique Identifier : AIDSLINE MED/92100160; Stanberry LR; Bernstein DI; Myers MG
Histopathologic findings of duodenal biopsy specimens in HIV-infected patients with and without diarrhea and malabsorption [see comments]: Am J Clin Pathol. 1992 Jan;97(1):21-8. Unique Identifier : AIDSLINE MED/92101988; Ehrenpreis ED; Patterson BK; Brainer JA; Yokoo H; Rademaker AW; Glogowski W; Noskin GA; Craig RM; Department of Medicine, Northwestern University Medical School,; Chicago, Illinois.; The significance of the human immunodeficiency virus (HIV) in the small intestinal lamina propria in patients with the acquired immune deficiency syndrome or conditions related to that syndrome who have chronic diarrhea and malabsorption is unclear. To investigate this issue, upper endoscopy (after a 12- to 16-hour fa
Use of antibody/peptide constructs of direct antigenic peptides to T cells: evidence for T cell processing and presentation.: Cell Immunol. 1992 Jan;139(1):268-73. Unique Identifier : AIDSLINE MED/92103708; Wyss-Coray T; Brander C; Bettens F; Mijic D; Pichler WJ; Institute of Clinical Immunology, Inselspital, Bern, Switzerland.; Human T cells can express MHC-class II products and were shown to be potential antigen-presenting cells. However, they are unable to capture the antigen and only antigens, which bind to T cell membranes such as the gp120 glycoprotein of HIV, are internalized, processed, and presented by T cells. To better understand t
Pneumococcal bacteremia with pneumonia. Mortality in acquired immunodeficiency syndrome.: Chest. 1992 Jan;101(1):150-5. Unique Identifier : AIDSLINE MED/92103955; Pesola GR; Charles A; Department of Medicine, St. Clare's Hospital, New York.; OBJECTIVE: To compare mortality due to bacteremic pneumococcal pneumonia in patients with acquired immunodeficiency syndrome (AIDS) vs (control) patients without human immunodeficiency virus (HIV) infection. Non-AIDS patients with HIV infection were incidentally tabulated as a separate group. DESIGN: A two-year retros
Upper lobe pulmonary parenchymal calcification in a patient with AIDS and Pneumocystis carinii pneumonia receiving aerosolized pentamidine.: Chest. 1992 Jan;101(1):266-7. Unique Identifier : AIDSLINE MED/92103981; Srivatsa SS; Burger CD; Douglas WW; Division of Thoracic Diseases and Internal Medicine, Mayo Clinic,; Rochester, Minnesota 55905.; In patients with AIDS-related Pneumocystis carinii infection occurring during aerosolized pentamidine prophylaxis, roentgenographic findings may be atypical. Pulmonary parenchymal calcification due to P carinii is rare. In this case, extensive upper lobe pulmonary parenchymal, splenic, and nodal calcifications occurre
Long-term follow-up of tuberculoma of the brain in an AIDS patient.: Chest. 1992 Jan;101(1):278-9. Unique Identifier : AIDSLINE MED/92103988; Malasky C; Reichman LB; University of Medicine and Dentistry of New Jersey, Newark.; Human immunodeficiency virus infection and extrapulmonary TB are defined as AIDS. The clinical manifestations of the TB are related to the interplay of the organism and the host s immune system. A seven-year follow-up of a woman successfully treated for biopsy- and culture-documented tuberculous brain abscess is descr
Eflornithine treatment of refractory Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome.: Chest. 1992 Jan;101(1):67-74. Unique Identifier : AIDSLINE MED/92104015; Paulson YJ; Gilman TM; Heseltine PN; Sharma OP; Boylen CT; School of Pharmacy, University of Southern California, Los; Angeles.; Eflornithine was offered as compassionate treatment of 33 episodes of Pneumocystis carinii pneumonia in 31 patients with acquired immunodeficiency syndrome who were intolerant of and/or unresponsive to conventional trimethoprim-sulfamethoxazole or pentamidine therapy. A full course of eflornithine consisted of ten day
High incidence of bronchospasm with regular administration of aerosolized pentamidine.: Chest. 1992 Jan;101(1):79-81. Unique Identifier : AIDSLINE MED/92104017; Katzman M; Meade W; Iglar K; Rachlis A; Berger P; Chan CK; Department of Medicine, Wellesley Hospital, Sunnybrook Medical; Center, Canada.; A systematic evaluation of changes in pulmonary status by objective spirometric assessment and subjective rating using visual analog scale was performed in a cohort of 134 patients receiving aerosolized pentamidine (AP) for the prevention of Pneumocystis carinii pneumonia. Significant bronchospasm defined as greater t
Deposition of aerosolized pentamidine and failure of pneumocystis prophylaxis.: Chest. 1992 Jan;101(1):82-7. Unique Identifier : AIDSLINE MED/92104019; Smaldone GC; Dickinson G; Marcial E; Young E; Seymour J; Department of Medicine, State University, Stony Brook, NY.; OBJECTIVE: To determine if outcome of Pneumocystis carinii prophylaxis is related to total lung dose of aerosolized pentamidine. SETTING: AIDS treatment centers at a VA and University Hospital. PATIENTS: Fifty-eight HIV-infected patients receiving P carinii prophylaxis with aerosolized pentamidine using a nebulizer (C
Data watch. Study: 21% rise in HIV treatment costs by 1994.: Hospitals. 1992 Jan 20;66(2):18. Unique Identifier : AIDSLINE MED/92104584
Significance of bowel wall enhancement on CT following blunt abdominal trauma in childhood.: J Comput Assist Tomogr. 1992 Jan-Feb;16(1):94-8. Unique Identifier : AIDSLINE MED/92105553; Hara H; Babyn PS; Bourgeois D; Department of Radiology, Hospital for Sick Children, Toronto,; Ontario, Canada.; Over a 3-year period, 12 children with blunt abdominal trauma were noted to have intense bowel wall enhancement (BWE) on CT. In four, with fatal CNS injury, there was no evidence of bowel perforation, and the changes may be related to the hypovolemic complex. In the remaining eight patients with a gastrointestinal per
Induction of IFN-alpha in peripheral blood mononuclear cells by HIV-infected monocytes. Restricted antiviral activity of the HIV-induced IFN.: J Immunol. 1992 Jan 15;148(2):422-9. Unique Identifier : AIDSLINE MED/92105736; Gendelman HE; Baca LM; Kubrak CA; Genis P; Burrous S; Friedman RM; Jacobs D; Meltzer MS; Department of Cellular Immunology, Walter Reed Army Institute of; Research, Washington, DC 20307-5100.; PBMC cocultured with HIV-infected monocytes for 12 to 48 h released high levels of IFN activity. IFN titers were directly dependent upon time after virus infection and level of HIV replication in infected cells. IFN induction in PBMC was evident with HIV-infected monocytes and PBMC and with myeloid and lymphoblastoid
Rural nursing research priorities.: J Nurs Adm. 1992 Jan;22(1):50-6. Unique Identifier : AIDSLINE MED/92106075; Bushy A; College of Nursing, University of Utah, Salt Lake City.; The magnitude and variety of clinical concerns in rural healthcare delivery mandate a focused plan for building a substantiated body of knowledge. The author identifies research priority areas to develop a body of knowledge for rural nursing.
Prostatic abscess due to Histoplasma capsulatum in a patient with the acquired immunodeficiency syndrome.: J Urol. 1992 Jan;147(1):166-8. Unique Identifier : AIDSLINE MED/92106385; Zighelboim J; Goldfarb RA; Mody D; Williams TW; Bradshaw MW; Harris RL; Department of Internal Medicine, Baylor College of Medicine,; Houston, Texas.; Disseminated histoplasmosis is a systemic fungal infection that may occur in previously healthy or immunocompromised patients. The condition is being recognized with increasing frequency in persons infected with the human immunodeficiency virus. The most common organs involved include the lung, bone marrow, lymph node
Re: Decreasing the risk of human immunodeficiency virus or hepatitis B virus infection during endoscopic surgery [letter; comment]: J Urol. 1992 Jan;147(1):174. Unique Identifier : AIDSLINE MED/92106395; Davies JH; Notley RG
Re: Decreasing the risk of human immunodeficiency virus or hepatitis B virus infection during endoscopic surgery [letter; comment]: J Urol. 1992 Jan;147(1):174. Unique Identifier : AIDSLINE MED/92106396; Fassuliotis TM
The treatment of AIDS-related lymphoma. French-Italian Cooperative Study Group [letter; comment]: JAMA. 1992 Jan 22-29;267(4):509-10. Unique Identifier : AIDSLINE MED/92106459; Tirelli U; Errante D; Oksenhendler E; Vaccher E; Gastaldi R; Rizzardini G; Monfardini S; Gisselbrecht C
Critical care of patients with AIDS.: JAMA. 1992 Jan 22-29;267(4):541-7. Unique Identifier : AIDSLINE MED/92106470; Wachter RM; Luce JM; Hopewell PC; Medical Service, San Francisco, General Hospital Medical Center,; University of California 94143-0862.; OBJECTIVE--We sought to review the clinical and ethical issues surrounding critical care for patients with the acquired immunodeficiency syndrome (AIDS). DATA SOURCES--We reviewed published studies and abstracts dealing with the outcome of critical care for patients with AIDS, decision making about life-sustaining tre
Variation in health service use among HIV-infected patients.: Med Care. 1992 Jan;30(1):17-29. Unique Identifier : AIDSLINE MED/92106833; Mor V; Fleishman JA; Dresser M; Piette J; Center for Gerontology and Health Care Research, Brown; University, Providence, RI 02912.; The effects of sociodemographic factors on health service use among people with human immunodeficiency virus (HIV) infection are assessed. Data are from a survey of 939 clients of the Robert Wood Johnson Foundation s AIDS Health Services Program in nine communities across the country. Dependent variables are the numbe
Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs.: Mol Cell Biol. 1992 Jan;12(1):207-19. Unique Identifier : AIDSLINE GENBANK/K03455; Schwartz S; Felber BK; Pavlakis GN; Human Retrovirus Section, National Cancer Institute-Frederick; Cancer Research and Development Center, Maryland 21702-1201.; We have used a panel of cDNA clones expressing wild-type and mutant human immunodeficiency virus type 1 (HIV-1) mRNAs to study translation of these mRNAs in eucaryotic cells. The tat open reading frame (ORF) has a strong signal for translation initiation, while rev and vpu ORFs have weaker signals. The expression of d
Seroprevalence of HTLV-1 and HTLV-2 among intravenous drug users and persons in clinics for sexually transmitted diseases.: N Engl J Med. 1992 Feb 6;326(6):375-80. Unique Identifier : AIDSLINE MED/92107230; Khabbaz RF; Onorato IM; Cannon RO; Hartley TM; Roberts B; Hosein B; Kaplan JE; Division of Viral and Rickettsial Diseases, Centers for Disease; Control, Atlanta, GA 30333.; Background. The human T-cell lymphotropic virus Type I (HTLV-I) is associated with adult T-cell leukemia and myelopathy, whereas HTLV-II infection has uncertain clinical consequences. We assessed the seroprevalence of these retroviruses among intravenous drug users and among patients seen at clinics for sexually trans
AIDS treatment. Confusion over therapy [news]: Nature. 1992 Jan 9;355(6356):102. Unique Identifier : AIDSLINE MED/92107285; Aldhous P
Sequence analysis of cytoplasmic mRNA-binding proteins of Xenopus oocytes identifies a family of RNA-binding proteins.: Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):11-5. Unique Identifier : AIDSLINE GENBANK/M80257; Murray MT; Schiller DL; Franke WW; Division of Membrane Biology and Biochemistry, German Cancer; Research Center, Heidelberg.; Storage of maternal mRNAs as nontranslated ribonucleoprotein (RNP) complexes is an adaptive strategy in various vertebrate and invertebrate oocytes, for rapid translational recruitment during embryonic development. Previously, we showed that Xenopus laevis oocytes have a soluble cytoplasmic pool of mRNA-binding protei
A mutation in the human immunodeficiency virus type 1 transmembrane glycoprotein gp41 dominantly interferes with fusion and infectivity.: Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):70-4. Unique Identifier : AIDSLINE MED/92108081; Freed EO; Delwart EL; Buchschacher GL Jr; Panganiban AT; McArdle Laboratory for Cancer Research, University of Wisconsin,; Madison 53706.; Several domains of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein have been identified that are involved in HIV-1-mediated membrane fusion. One domain that is involved in membrane fusion is the hydrophobic amino terminus of the HIV-1 transmembrane glycoprotein gp41. Here we show that a polar sub
Regs put new legal force behind universal precautions [news]: Am J Nurs. 1992 Jan;92(1):82, 84. Unique Identifier : AIDSLINE MED/92109268
OSHA releases final standard on HIV, hepatitis B exposures.: Am Nurse. 1992 Jan;24(1):1, 19. Unique Identifier : AIDSLINE MED/92109367; Richardson D
Effect of recombinant human growth hormone on acute and chronic human immunodeficiency virus infection in vitro.: Blood. 1992 Jan 15;79(2):467-72. Unique Identifier : AIDSLINE MED/92110581; Laurence J; Grimison B; Gonenne A; Laboratory for AIDS Virus Research, New York Hospital, NY.; Growth hormone (somatotropin) is a potent anabolic protein currently being evaluated clinically in cachexia associated with malignancy and human immunodeficiency virus (HIV) disease. Growth hormone can also lead to enhancement of lectin-mediated cellular proliferation, macrophage activation, and cytokine induction, ev
Cellular composition of germinal centers in lymph nodes after HIV-1 infection: evidence for an inadequate support of germinal center B lymphocytes by follicular dendritic cells.: Clin Immunol Immunopathol. 1992 Feb;62(2):148-59. Unique Identifier : AIDSLINE MED/92110958; Rademakers LH; Schuurman HJ; de Frankrijker JF; Van Ooyen A; Department of Pathology, University Hospital Utrecht, The; Netherlands.; Germinal centers in lymph nodes with follicular hyperplasia from 15 patients with HIV-1 infection were analyzed by qualitative and quantitative electron microscopical methods and compared with control follicular hyperplasia (FH). Using a pattern recognition method, two main clusters were recognized within the germinal
Monocyte-derived macrophage function in HIV-infected subjects: in vitro modulation by rIFN-gamma and rGM-CSF.: Clin Immunol Immunopathol. 1992 Feb;62(2):176-82. Unique Identifier : AIDSLINE MED/92110961; Capsoni F; Minonzio F; Ongari AM; Rizzardi GP; Lazzarin A; Zanussi C; Instituto di Medicina Interna, Malattie Infettive e; Immunopatologia, University of Milan, Italy.; We investigated monocyte-derived macrophage function in 25 HIV-positive patients, 19 in the CDC class III and 6 class IV; 17 were intravenous drug abusers (IVDA) and 8 were homosexual men. Macrophages from HIV-positive patients behaved normally in assays of superoxide anion (O2-) production and candidacidal activity.
Dermatopathologic findings in patients infected with HIV.: Dermatol Clin. 1992 Jan;10(1):59-71. Unique Identifier : AIDSLINE MED/92110982; LeBoit PE; Department of Pathology, University of California School of; Medicine, San Francisco.; Several inflammatory, infectious, and neoplastic conditions in HIV-infected patients are distinctive or require a biopsy for diagnosis. Some differ subtly from similar conditions seen in noninfected patients. The exanthem of acute HIV infection cannot be diagnosed specifically on biopsy as its histologic appearance is
Leprosy.: Dermatol Clin. 1992 Jan;10(1):73-96. Unique Identifier : AIDSLINE MED/92110983; Meyers WM; Armed Forces Institute of Pathology, Washington, DC.; Growing out of the successful transmission of leprosy to armadillos, making available large quantities of M. leprae, there have been remarkable recent advances in the knowledge of the leprosy bacillus. These bacilli and their isolated chemical constituents provide organisms for in vitro testing of new drugs, reagents
Criteria for use of zidovudine in adult and pediatric inpatients and outpatients.: Clin Pharm. 1992 Jan;11(1):63-8. Unique Identifier : AIDSLINE MED/92111103; Goodwin SD; Shipp KW; Division of Pharmacy Practice, School of Pharmacy, University of; Colorado Health Sciences Center, Denver.
Pneumonia. Patient profiles, choice of empiric therapy, and the place of third-generation cephalosporins.: Diagn Microbiol Infect Dis. 1992 Jan;15(1):57-65. Unique Identifier : AIDSLINE MED/92111118; Leedom JM; University of Southern California Medical Center, Los Angeles; 90033.; Choosing appropriate antimicrobial therapy for patients with pneumonia requires knowledge of the etiologic agents seen in specific kinds of patients at specific times and places. For community-acquired pneumonia, there is an important difference in the agents seen in the normal and the compromised host. The normal hos
HIV counseling and testing of psychiatric patients: time to reexamine policy and practices [editorial; comment]: Gen Hosp Psychiatry. 1992 Jan;14(1):1-2. Unique Identifier : AIDSLINE MED/92112007; Ostrow DG
Assessing HIV risk in the general hospital psychiatric clinic [see comments]: Gen Hosp Psychiatry. 1992 Jan;14(1):3-6. Unique Identifier : AIDSLINE MED/92112011; Hellerstein DJ; Prager ME; Department of Psychiatry, Beth Israel Medical Center, New York,; New York 10003.; Of 101 new admissions to an urban outpatient psychiatric clinic, 17 (16.8%) were known to be at high risk and 11 (10.9%) at suspected high risk for developing or transmitting HIV infection, but apparently few were appropriately counseled. This suggests a need for implementing specific policies and procedures for HIV a
Characterization of inhibition of Mycobacterium avium replication in macrophages by normal human serum.: Infect Immun. 1992 Feb;60(2):345-52. Unique Identifier : AIDSLINE MED/92112289; Douvas GS; May MH; Ross E; Crowle AJ; Division of Immunology, Webb-Waring Lung Institute, Denver,; Colorado.; Serum from some AIDS patients permits the rapid multiplication of Mycobacterium avium in cultured human macrophages. Serum from human immunodeficiency virus-negative individuals inhibits replication. The characteristics of the serum-induced inhibition were examined here. M. avium 7497 serovar 4 grew exponentially in m
HTLV-I-positive and HTLV-I-negative peripheral T-cell lymphomas in Taiwan Chinese.: Int J Cancer. 1992 Jan 21;50(2):186-91. Unique Identifier : AIDSLINE MED/92112362; Shih LY; Kuo TT; Dunn P; Liaw SJ; Department of Internal Medicine, Chang Gung Memorial Hospital,; Chang Gung Medical College, Taipei, Taiwan, Republic of China.; The clinico-pathologic features of 107 adult Chinese patients with peripheral T-cell lymphoma (excluding primary cutaneous lymphoma) are described and a comparison between HTLVI+ and HTLV-I- patients is made. There were 27 HTLV-I+ and 80 HTLV-I- patients. The virus-positive and -negative groups both had a male predomi
Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells.: Int J Cancer. 1992 Jan 21;50(2):289-97. Unique Identifier : AIDSLINE MED/92112377; Coulie PG; Somville M; Lehmann F; Hainaut P; Brasseur F; Devos R; Boon T; Ludwig Institute for Cancer Research, Bruxelles, Belgium.; Limiting numbers of peripheral-blood mononuclear cells (PBMC) from melanoma patients were stimulated with irradiated autologous tumor cells in the presence of interleukins-2 and -4 and in the absence of feeder cells. The responder cells were restimulated every week. After 2 to 4 weeks, the microcultures were tested fo
Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus.: J Biol Chem. 1992 Jan 5;267(1):257-60. Unique Identifier : AIDSLINE MED/92112659; Chen MS; Suttmann RT; Wu JC; Prisbe EJ; Institute of Cancer and Developmental Biology, Syntex Research,; Palo Alto, California 94304.; 4 -Azidothymidine (ADRT) is a novel nucleoside analog, that selectively inhibits human immunodeficiency virus replication in human lymphocytes. Unlike the dideoxyribonucleoside analogs and 3 -azido-2 ,3 -dideoxythymidine ( AZT ), ADRT retains the 3 -hyd
Interactions of azidothymidine triphosphate with the cellular DNA polymerases alpha, delta, and epsilon and with DNA primase.: J Biol Chem. 1992 Jan 15;267(2):848-54. Unique Identifier : AIDSLINE MED/92112818; Nickel W; Austermann S; Bialek G; Grosse F; Max-Planck-Institut fur Experimentelle Medizin, Abetilung; Chemie, Gottingen, Germany.; The interactions of azidothymidine triphosphate, the metabolically active form of the anti-AIDS drug azidothymidine (zidovudine), with the cellular DNA polymerases alpha, delta, and epsilon, as well as with the RNA primer-forming enzyme DNA primase were studied in vitro. DNA polymerase alpha was shown to incorporate a
Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1.: J Biol Chem. 1992 Jan 25;267(3):1904-9. Unique Identifier : AIDSLINE MED/92112920; Heidenreich O; Eckstein F; Max-Planck-Institut fur Experimentelle Medizin, Gottingen,; Federal Republic of Germany.; Three ribozymes targeted against different sites of the long terminal repeat RNA (LTR RNA) of human immunodeficiency virus type 1 cleaved a LTR RNA transcript 1,000 x less efficiently than corresponding short synthetic oligoribonucleotide substrates. Varying the stem lengths of the ribozyme resulted in changes of the
AIDS--the second decade: a global perspective.: J Infect Dis. 1992 Feb;165(2):245-50. Unique Identifier : AIDSLINE MED/92113328; Mann JM; Department of Epidemiology, Harvard School of Public Health,; Boston, Massachusetts 02115.; The human immunodeficiency virus (HIV) and AIDS epidemic merits its designation as a pandemic: AIDS cases are reported to the World Health Organization from 163 countries, and at least 10 million adults have been infected with HIV. The pandemic is a relatively new phenomenon, and there
Increased risk of early measles in infants of human immunodeficiency virus type 1-seropositive mothers.: J Infect Dis. 1992 Feb;165(2):262-7. Unique Identifier : AIDSLINE MED/92113331; Embree JE; Datta P; Stackiw W; Sekla L; Braddick M; Kreiss JK; Pamba H; Wamola I; Ndinya-Achola JO; Law BJ; et al; Department of Medical Microbiology, University of Manitoba,; Winnipeg, Canada.; An increase in illness due to measles is one of the potential consequences of the human immunodeficiency virus (HIV) epidemic in Africa. During a study of perinatal HIV transmission conducted in Kenya , the risk of acquiring measles before vaccination (9 months of age) was found to b
Passive immunotherapy in AIDS: a randomized trial of serial human immunodeficiency virus-positive transfusions of plasma rich in p24 antibodies versus transfusions of seronegative plasma.: J Infect Dis. 1992 Feb;165(2):364-8. Unique Identifier : AIDSLINE MED/92113344; Vittecoq D; Mattlinger B; Barre-Sinoussi F; Courouce AM; Rouzioux C; Doinel C; Bary M; Viard JP; Bach JF; Rouger P; et al; Unite de Traitement des Maladies Infectieuses et Dysimmunitaires; and Hopital Necker, Paris, France.; To assess the place of passive immunotherapy in the treatment of AIDS, a randomized study was conducted that evaluated the safety and short-term efficacy of serial transfusions of human immunodeficiency virus type 1 (HIV-1) seropositive plasma in 18 patients. Heat-inactivated anti-HIV antibody-rich plasma was compared
Human T lymphotropic virus (HTLV) type I and II DNA amplification in HTLV-I/II-seropositive blood donors of the French West Indies.: J Infect Dis. 1992 Feb;165(2):369-72. Unique Identifier : AIDSLINE MED/92113345; Wattel E; Mariotti M; Agis F; Gordien E; Prou O; Courouce AM; Rouger P; Wain-Hobson S; Chen IS; Lefrere JJ; Laboratoire de Biologie Moleculaire, Institut National de; Transfusion Sanguine, Paris, France.; To confirm the presence of DNA from human T lymphotropic virus type I (HTLV-I), HTLV-II, or both in individuals found HTLV-I/II-positive through systematic screening of blood donations in Guadeloupe (French West Indies), 42 blood do
Early diagnosis of human immunodeficiency virus infection in infants by detection of free and complexed p24 antigen [letter]: J Infect Dis. 1992 Feb;165(2):394-5. Unique Identifier : AIDSLINE MED/92113352; Palomba E; Gay V; de Martino M; Fundaro C; Perugini L; Tovo PA
Construction of a binding site for human immunodeficiency virus type 1 gp120 in rat CD4.: J Exp Med. 1992 Jan 1;175(1):301-4. Unique Identifier : AIDSLINE MED/92113475; Schockmel GA; Somoza C; Davis SJ; Williams AF; Healey D; Medical Research Council Cellular Immunology Unit, Sir William; Dunn School of Pathology, University of Oxford, United Kingdom.; The human immunodeficiency virus (HIV-1) infects T lymphocytes via an interaction between the virus envelope glycoprotein gp120 and the CD4 antigen of T helper cells. Previous studies demonstrated that mutations in various regions of CD4 domain 1 lead to the loss of gp120 binding. In the present study the gp120 bindin
Cells surviving infection by human immunodeficiency virus type 1: vif or vpu mutants produce non-infectious or markedly less cytopathic viruses.: J Gen Virol. 1992 Jan;73 ( Pt 1):77-87. Unique Identifier : AIDSLINE MED/92113582; Kishi M; Nishino Y; Sumiya M; Ohki K; Kimura T; Goto T; Nakai M; Kakinuma M; Ikuta K; Institute of Immunological Science, Hokkaido University, Sapporo,; Japan.; Under conditions in which a clonal cell line (M10) isolated from a human T cell lymphotrophic virus type I-transformed MT-4 cell line was completely killed by infection with wild-type human immunodeficiency virus type 1 (HIV-1), equivalent M10 cells survived infection with HIV-1 vif, vpr or vpu mutant virus after tran
Technetium-99m-DTPA aerosol and gallium-67 scanning in pulmonary complications of human immunodeficiency virus infection.: J Nucl Med. 1992 Jan;33(1):81-7. Unique Identifier : AIDSLINE MED/92113712; Rosso J; Guillon JM; Parrot A; Denis M; Akoun G; Mayaud C; Scherrer M; Meignan M; Hopital Henri Mondor, Service de Medecine Nucleaire, Creteil,; France.; We retrospectively compared the results of 67Ga chest scans and 99mTc-DTPA aerosol clearance measurements with those of fiberoptic bronchoscopy in 88 patients infected with the human immunodeficiency virus. Of 100 investigations, a pulmonary infection was diagnosed in 39, mainly Pneumocystis carinii pneumonia and a no
Meningoencephalitis in a neonate congenitally infected with human immunodeficiency virus type 1.: J Pediatr. 1992 Jan;120(1):93-5. Unique Identifier : AIDSLINE MED/92113840; Srugo I; Wittek AE; Israele V; Brunell PA; Division of Pediatric Infectious Diseases, Ahmanson Pediatric; Center, Los Angeles, CA 90048.; A newborn infant born to a mother infected with human immunodeficiency virus type 1 had acute meningoencephalitis on the second day of life. Human immunodeficiency virus type 1 was isolated from the plasma, cerebrospinal fluid, and peripheral blood mononuclear cells. Specific IgM for human immunodeficiency virus type
Complex formation of human T-cell leukemia virus type I p40tax transactivator with cellular polypeptides.: J Virol. 1992 Feb;66(2):1040-9. Unique Identifier : AIDSLINE MED/92114125; Nagata K; Ide Y; Takagi T; Ohtani K; Aoshima M; Tozawa H; Nakamura M; Sugamura K; Department of Microbiology, Tohoku University School of Medicine,; Sendai, Japan.; We examined cellular components which associate with p40tax, the viral transactivation molecule of human T-cell leukemia virus type I. Such molecules were searched by immunoprecipitation with polyclonal and monoclonal antibodies specific for p40tax. Two cellular proteins with molecular masses of 95 kDa (p95) and 60 kD
Extensive sequence-specific information throughout the CAR/RRE, the target sequence of the human immunodeficiency virus type 1 Rev protein.: J Virol. 1992 Feb;66(2):1139-51. Unique Identifier : AIDSLINE MED/92114136; Dayton ET; Konings DA; Powell DM; Shapiro BA; Butini L; Maizel JV; Dayton AI; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, Bethesda, Maryland 20892.; The significance and location of sequence-specific information in the CAR/RRE, the target sequence for the Rev protein of the human immunodeficiency virus type 1 (HIV-1), have been controversial. We present here a comprehensive experimental and computational approach combining mutational analysis, phylogenetic compari
Differential susceptibilities of U-937 cell clones to infection by human immunodeficiency virus type 1.: J Virol. 1992 Feb;66(2):1183-7. Unique Identifier : AIDSLINE MED/92114141; Boulerice F; Geleziunas R; Bour S; Li HL; D'Addario M; Roulston A; Hiscott J; Wainberg MA; Lady Davis Institute for Medical Research, Sir Mortimer B.; Davis-Jewish General Hospital, Chemin Cote-Ste-Catherine, Quebec,; Canada.; Single-cell clones derived from the U-937 monocytic cell line were studied for susceptibility to infection by human immunodeficiency virus type 1 (HIV-1). Of four such clones, we found that three (UC12, UC14, and UC18) supported replication of HIV-1 more efficiently than parental U-937 cells, as measured by reverse tr
Defective interfering influenza virus inhibits immunopathological effects of infectious virus in the mouse.: J Virol. 1992 Feb;66(2):1188-92. Unique Identifier : AIDSLINE MED/92114142; Morgan DJ; Dimmock NJ; Department of Biological Sciences, University of Warwick,; Coventry, United Kingdom.; Mice inoculated intranasally with a lethal dose of standard influenza virus die with an immune-mediated pneumonia but are protected by coinoculation with defective interfering (DI) virus. Here we show that recruitment of immune cells into the infected lung is halved by treatment with DI virus although the CD4+/CD8+ ce
Conserved cysteine residues in the human immunodeficiency virus type 1 transmembrane envelope protein are essential for precursor envelope cleavage.: J Virol. 1992 Feb;66(2):1207-9. Unique Identifier : AIDSLINE MED/92114146; Dedera D; Gu RL; Ratner L; Department of Medicine, Washington University School of Medicine,; St. Louis, Missouri 63110.; The transmembrane (TM) protein of human immunodeficiency virus type 1 has been demonstrated to be involved in viral infectivity and syncytium formation. Two highly conserved cysteine residues in the extracellular region of the TM protein are shown to be essential for processing the 160-kDa envelope precursor into the
Human immunodeficiency virus type 1 and type 2 protease monomers are functionally interchangeable in the dimeric enzymes.: J Virol. 1992 Feb;66(2):1228-31. Unique Identifier : AIDSLINE MED/92114151; Patterson CE; Seetharam R; Kettner CA; Cheng YS; DuPont Merck Pharmaceutical Company, Wilmington, Delaware; 19880-0328.; Human immunodeficiency virus type 1 (HIV-1) and HIV-2 proteases are dimers of identical subunits. We made a construct for the expression of recombinant one-chain HIV-2 protease dimer, which, like the previously described one-chain HIV-1 protease dimer, is fully active. The constructs for the one-chain dimers of HIV-1
Resistance to respiratory syncytial virus (RSV) challenge induced by infection with a vaccinia virus recombinant expressing the RSV M2 protein (Vac-M2) is mediated by CD8+ T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies.: J Virol. 1992 Feb;66(2):1277-81. Unique Identifier : AIDSLINE MED/92114160; Connors M; Kulkarni AB; Collins PL; Firestone CY; Holmes KL; Morse HC 3d; Murphy BR; Respiratory Viruses Section, National Institute of Allergy and; Infectious Diseases, Bethesda, Maryland 20892.; It was previously demonstrated that the vaccinia virus recombinants expressing the respiratory syncytial virus (RSV) F, G, or M2 (also designated as 22K) protein (Vac-F, Vac-G, or Vac-M2, respectively) induced almost complete resistance to RSV challenge in BALB/c mice. In the present study, we sought to identify the h
Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity.: J Virol. 1992 Feb;66(2):757-65. Unique Identifier : AIDSLINE MED/92114178; de Jong JJ; Goudsmit J; Keulen W; Klaver B; Krone W; Tersmette M; de Ronde A; Human Retrovirus Laboratory, The Netherlands Red Cross Blood; Transfusion Service, Amsterdam.; Chimeric human immunodeficiency virus type 1 (HIV-1) molecular clones differing only in the envelope V3 region were constructed. The V3 regions were derived from two HIV-1 isolates with a non-syncytium-inducing, non-T-cell-tropic phenotype and from four HIV-1 isolates with a syncytium-inducing, T-cell-tropic phenotype
Tightly bound zinc in human immunodeficiency virus type 1, human T-cell leukemia virus type I, and other retroviruses.: J Virol. 1992 Feb;66(2):840-7. Unique Identifier : AIDSLINE MED/92114187; Bess JW Jr; Powell PJ; Issaq HJ; Schumack LJ; Grimes MK; Henderson LE; Arthur LO; AIDS Vaccine Program, National Cancer Institute-Frederick Cancer; Research and Development Center, Maryland 21702-1201.; Human immunodeficiency virus type 1 (HIV-1) and human T-cell leukemia virus type I (HTLV-I) were purified by sucrose density gradient centrifugation in the presence of 1 mM EDTA. Pelleted gradient fractions were analyzed for total protein, total Gag capsid protein, and total zinc. Zinc was found to copurify and concen
Human immunodeficiency virus type 1 envelope gene structure and diversity in vivo and after cocultivation in vitro.: J Virol. 1992 Feb;66(2):875-85. Unique Identifier : AIDSLINE GENBANK/M79354; Kusumi K; Conway B; Cunningham S; Berson A; Evans C; Iversen AK; Colvin D; Gallo MV; Coutre S; Shpaer EG; et al; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.; Nested-primer polymerase chain reaction (PCR) has been applied to the molecular cloning of 4.6-kb half-genome fragments of human immunodeficiency virus type 1 (HIV-1) taken directly from the peripheral blood mononuclear cells (PBMC) of an individual with neurological symptoms of HIV-1 infection. In a similar manner, g
Unusual structure of the human immunodeficiency virus type 1 trans-activation response element.: J Virol. 1992 Feb;66(2):930-5. Unique Identifier : AIDSLINE MED/92114197; Colvin RA; Garcia-Blanco MA; Section of Cell Growth, Regulation and Oncogenesis, Duke; University Medical Center, Durham, North Carolina 27710.; The trans-activation response element (TAR) of human immunodeficiency virus type 1 is a structured RNA consisting of the first 60 nucleotides of all human immunodeficiency virus type 1 RNAs. Computer analyses and limited structural analyses indicated that TAR consists of a stem-bulge-loop structure. Mutational analyse
Scientific misconduct. A final frenzy for landmark cases? [news]: Nature. 1992 Jan 2;355(6355):6-7. Unique Identifier : AIDSLINE MED/92114935; Anderson C
Daniel Zagury cleared of misconduct charges [news]: Nature. 1992 Jan 23;355(6358):286. Unique Identifier : AIDSLINE MED/92114977; Culliton BJ
AIDS and malaria experiments [letter; comment]: Nature. 1992 Jan 23;355(6358):305. Unique Identifier : AIDSLINE MED/92114992; Gosden RG
AIDS and malaria experiments [letter; comment]: Nature. 1992 Jan 23;355(6358):305. Unique Identifier : AIDSLINE MED/92114993; Kuvin SF
HIV testing: promote a rational approach... [letter; comment]: Nurs Manage. 1992 Jan;23(1):12. Unique Identifier : AIDSLINE MED/92115203; Woods BJ
What was the source? [letter; comment]: Nurs Manage. 1992 Jan;23(1):12. Unique Identifier : AIDSLINE MED/92115205; Thompson RC
Healthcare workers and occupational exposure to AIDS.: Nurs Manage. 1992 Jan;23(1):59-60. Unique Identifier : AIDSLINE MED/92115223; Levine AS; Goody MM
OSHA final bloodborne standard expected to prevent more than 9,200 infections and 200 deaths per year. Occupational Safety and Health Administration.: Pa Nurse. 1992 Jan;47(1):10. Unique Identifier : AIDSLINE MED/92115358
Perforin and granzyme A expression identifying cytolytic lymphocytes in rheumatoid arthritis.: Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):549-53. Unique Identifier : AIDSLINE MED/92115698; Griffiths GM; Alpert S; Lambert E; McGuire J; Weissman IL; Howard Hughes Medical Institute, Stanford University, CA 94305.; Lymphocytes from the synovial fluid of patients with rheumatoid arthritis were examined for the expression of granzyme A and perforin. Previous studies have demonstrated that the expression of these proteins, which are implicated as mediators of cytotoxicity, can be used to identify putative cytolytic lymphocytes in v
Treatment of premalignancy: prevention of lymphoma in radiation leukemia virus-inoculated mice by cyclosporin A and immunotoxin.: Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):728-32. Unique Identifier : AIDSLINE MED/92115734; Yefenof E; Abboud G; Epszteyn S; Vitetta ES; Lautenberg Center for General and Tumor Immunology, Hebrew; University-Hadassa Medical School, Jerusalem, Israel.; Radiation leukemia virus (RadLV)-induced preleukemic (PL) latency is characterized by the appearance of virus-infected PL cells in the thymus. The survival of these PL cells is dependent upon autostimulation with interleukin 4 (IL-4). We have intervened prophylactically in RadLV-induced preleukemia by using cyclospori
Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein [published erratum appears in Proc Natl Acad Sci U S A 1992 Mar 1;89(5):1997]: Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):758-62. Unique Identifier : AIDSLINE MED/92115740; Tiley LS; Malim MH; Tewary HK; Stockley PG; Cullen BR; Howard Hughes Medical Institute, Duke University Medical Center,; Durham, NC 27710.; Expression of the structural proteins of human immunodeficiency virus type 1 requires the direct interaction of multiple copies of the viral Rev protein with its highly structured RNA target sequence, the Rev response element (RRE). Nucleotides critical for Rev monomer binding have been mapped by chemical interference
Ischemic stroke as the sole manifestation of human immunodeficiency virus infection [letter]: Stroke. 1992 Jan;23(1):117-8. Unique Identifier : AIDSLINE MED/92116406; Casado Naranjo I; Toledo Santos JA; Antolin Rodriguez MA
Transmission of human T-lymphotropic virus type I by blood components from a donor lacking anti-p24: a case report. The Transfusion Safety Study Group.: Transfusion. 1992 Jan;32(1):68-71. Unique Identifier : AIDSLINE MED/92116436; Donegan E; Pell P; Lee H; Shaw GM; Mosley JW; University of California, San Francisco.; The present criteria for confirmation of human T-lymphotrophic virus types I and II (HTLV-I/II) infection in blood donors are based on seroreactivity to p24 (gag) and gp46 and/or gp61 (env) on Western blot (WB) and radioimmunoprecipitation assays (WB/RIPA). Any single band and other combinations are classified as inde
Human T-lymphotropic virus type I infection among blood donors in the Solomon Islands [letter]: Transfusion. 1992 Jan;32(1):89. Unique Identifier : AIDSLINE MED/92116444; Yanagihara R; Hefner C; Ajdukiewicz AB
Spinal cord syphilis associated with human immunodeficiency virus infection: a treatable myelopathy.: Am J Med. 1992 Jan;92(1):101-3. Unique Identifier : AIDSLINE MED/92117044; Berger JR; Department of Neurology, University of Miami School of Medicine,; Florida 33151.; A 33-year-old woman, seropositive for human immunodeficiency virus type 1 (HIV-1), presented with progressive weakness and numbness of the lower extremities, gait difficulties, and urinary frequency. Physical examination revealed bilateral lower extremity weakness, a left-sided Babinski reflex, and a thoracic sensory
Methadone and immune function [letter; comment] [see comments]: Am J Med. 1992 Jan;92(1):113-5. Unique Identifier : AIDSLINE MED/92117051; Novick DM; Kreek MJ
Occupational exposure to HIV [letter; comment]: Am J Med. 1992 Jan;92(1):115-6. Unique Identifier : AIDSLINE MED/92117052; Schinstock B; Schaffer B
The risks of blood transfusion: the relative influence of acquired immunodeficiency syndrome and non-A, non-B hepatitis [see comments]: Am J Med. 1992 Jan;92(1):45-52. Unique Identifier : AIDSLINE MED/92117058; Carson JL; Russell LB; Taragin MI; Sonnenberg FA; Duff AE; Bauer S; Division of General Internal Medicine, University of Medicine and; Dentistry, New Jersey-Robert Wood Johnson Medical School, New; Brunswick 08903.; PURPOSE: The acquired immunodeficiency syndrome epidemic has greatly increased concern about the risk of blood transfusion. Many transfusions are now autologous, and when these are not available, both physicians and patients are more likely to question the advisability of transfusion. We evaluate the risk of preoperat
Low levels of human immunodeficiency virus replication in the brain tissue of children with severe acquired immunodeficiency syndrome encephalopathy.: Am J Pathol. 1992 Jan;140(1):137-44. Unique Identifier : AIDSLINE MED/92117072; Vazeux R; Lacroix-Ciaudo C; Blanche S; Cumont MC; Henin D; Gray F; Boccon-Gibod L; Tardieu M; Viral Oncology Unit, Pasteur Institute, Paris, France.; The authors examined the autopsy brain samples of nine children infected with human immunodeficiency virus (HIV) at birth by histology, immunologic staining, and in situ hybridization. Surprisingly, although seven of these children presented with typical AIDS encephalopathy, the authors could detect a multifocal HIV i
Strategy for AIDS.: Aust N Z J Surg. 1992 Jan;62(1):83-4. Unique Identifier : AIDSLINE MED/92117948; Parker BJ
[A case of subacute sclerosing panencephalitis developing 8 years after immunosuppressive treatment for acute lymphocytic leukemia]: No To Hattatsu. 1992 Jan;24(1):60-4. Unique Identifier : AIDSLINE MED/92118436; Fukuya H; Ohfu M; Tomoda Y; Nibu K; Ichiki S; Mitsudome A; Department of Pediatrics, School of Medicine, Fukuoka University.; A 13-year-old girl developed subacute sclerosing panencephalitis (SSPE) with atypical absence attacks as an initial symptom. Eight years earlier she had been treated for acute lymphocytic leukemia with cytotoxic treatment and radiotherapy, which had resulted in complete remission. She was first treated with an anticon
Hepatitis associated with primary HIV infection [letter]: Gastroenterology. 1992 Feb;102(2):739. Unique Identifier : AIDSLINE MED/92120414; Molina JM; Welker Y; Ferchal F; Decazes JM; Shenmetzler C; Modai J
Cerebrospinal fluid anti-cerebellar soluble lectin antibodies in human immunodeficiency virus type 1 infection.: J Neuroimmunol. 1992 Feb;36(2-3):245-9. Unique Identifier : AIDSLINE MED/92121423; Hagberg L; Norkrans G; Zanetta JP; Lehmann S; Bergstrom T; Department of Infectious Diseases, University of Goteborg,; Sweden.; Cerebrospinal fluid samples from 14 human immunodeficiency type 1 (HIV-1) seropositive patients in various stages of HIV infection were tested for the presence of autoantibodies to an endogenous manose-binding protein, the cerebellar soluble lectin (CSL), which has recently been found to be detected in a high proporti
Polymorphous cutaneous cryptococcosis: nodular, herpes-like, and molluscum-like lesions in a patient with the acquired immunodeficiency syndrome.: J Am Acad Dermatol. 1992 Jan;26(1):122-4. Unique Identifier : AIDSLINE MED/92121520; Manrique P; Mayo J; Alvarez JA; Ganchegui X; Zabalza I; Flores M; Department of Dermatology, Hospital de Galdacano, Vizcaya,; Spain.
The scintigraphic appearance of Alzheimer's disease: a prospective study using technetium-99m-HMPAO SPECT [published erratum appears in J Nucl Med 1992 Apr;33(4):484] [see comments]: J Nucl Med. 1992 Feb;33(2):181-5. Unique Identifier : AIDSLINE MED/92121958; Holman BL; Johnson KA; Gerada B; Carvalho PA; Satlin A; Department of Radiology, Brigham and Women's Hospital, Boston,; Massachusetts 02115.; Alzheimer s disease produces regional abnormalities in brain blood flow and metabolism that may result in recognizable scintigraphic patterns. We determined the predictive value of 99mTc-HMPAO SPECT for the presence of Alzheimer s disease based on a prospective study of 132 consecutive patients coming to our nuclear m
Plasma viremia in human immunodeficiency virus infection: relationship to stage of disease and antiviral treatment.: J Acquir Immune Defic Syndr. 1992;5(2):107-12. Unique Identifier : AIDSLINE MED/92122094; Katzenstein DA; Holodniy M; Israelski DM; Sengupta S; Mole LA; Bubp JL; Merigan TC; Center for AIDS Research, Stanford University Medical Center, CA; 94305.; Quantitative culture of human immunodeficiency virus (HIV) was performed on 121 plasma samples from 76 HIV-infected individuals to determine the sensitivity of the assay at different stages of disease and to measure the effect of antiviral therapy on plasma viremia. Plasma virus was detected in 49 of 76 (64%) of patie
Diagnosis of vertical HIV-1 transmission using the polymerase chain reaction and dried blood spot specimens.: J Acquir Immune Defic Syndr. 1992;5(2):113-9. Unique Identifier : AIDSLINE MED/92122095; Cassol SA; Lapointe N; Salas T; Hankins C; Arella M; Fauvel M; Delage G; Boucher M; Samson J; Charest J; et al; Federal Centre For AIDS, Health and Welfare Canada, Ottawa,; Ontario.; We have used the polymerase chain reaction (PCR) to detect HIV proviral sequences in minute amounts of peripheral blood collected onto newborn screening blotters. Forty-three newborns, infants, and children of HIV-infected mothers were serially studied: dried blood spot (DBS) specimens were processed for PCR; serum wa
The effect of antiviral therapy on the natural history of human immunodeficiency virus infection in a cohort of hemophiliacs [see comments]: J Acquir Immune Defic Syndr. 1992;5(2):120-6. Unique Identifier : AIDSLINE MED/92122096; Ragni MV; Kingsley LA; Zhou SJ; Department of Medicine, University of Pittsburgh School of; Medicine, PA 15219.; The antiviral drug zidovudine (ZDV) slows progression to AIDS and improves survival after AIDS diagnosis. Although clinical trials have demonstrated early improvement in CD4 lymphocyte number with ZDV, long-term effects of ZDV on CD4 in advanced and asymptomatic disease are not well known. The purpose of this study wa
Autopsy findings in HIV-infected inner-city patients.: J Acquir Immune Defic Syndr. 1992;5(2):132-6. Unique Identifier : AIDSLINE MED/92122098; Afessa B; Greaves W; Green W; Olopoenia L; Delapenha R; Saxinger C; Frederick W; Department of Medicine, Howard University College of Medicine,; Washington, D.C.; To assess the importance of the autopsy in HIV-1 infection, we retrospectively reviewed the autopsy reports of 70 HIV-1-seropositive patients at Howard University Hospital. Of the 58 patients with AIDS, the diagnosis of AIDS was made after autopsy in 24 (41%) cases. The lung was the most common site of AIDS-diagnostic
Pyrimethamine alone as maintenance therapy for central nervous system toxoplasmosis in 38 patients with AIDS.: J Acquir Immune Defic Syndr. 1992;5(2):137-42. Unique Identifier : AIDSLINE MED/92122099; de Gans J; Portegies P; Reiss P; Troost D; van Gool T; Lange JM; Department of Neurology, Academisch Medisch Centrum, Amsterdam,; The Netherlands.; We retrospectively assessed the efficacy of maintenance therapy with pyrimethamine alone in 38 patients with AIDS and central nervous system (CNS) toxoplasmosis. The diagnosis was based on clinical presentation and compatible CT scan abnormalities with subsequent response to therapy. Survival analysis was performed by
The relationship between AIDS and immunologic tolerance.: J Acquir Immune Defic Syndr. 1992;5(2):143-7. Unique Identifier : AIDSLINE MED/92122100; Sheppard HW; Ascher MS; Division of Laboratories, California Department of Health; Services, Berkeley 94704.; A hypothesis is presented in which the immunodeficiency and cell loss leading to acquired immune deficiency syndrome and the clonal deletion associated with immunologic tolerance occur through a common mechanism. In a previous publication we proposed that the interaction of human immunodeficiency virus (HIV) with CD4
Lack of association between maternal antibodies to V3 loop peptides and maternal-infant HIV-1 transmission.: J Acquir Immune Defic Syndr. 1992;5(2):153-7. Unique Identifier : AIDSLINE MED/92122102; Halsey NA; Markham R; Wahren B; Boulos R; Rossi P; Wigzell H; Department of International Health, Johns Hopkins University,; School of Hygiene and Public Health, Baltimore, Maryland 21205.; We investigated the association between maternal antibodies to HIV-1 peptides in pregnant women and the acquisition of HIV-1 infection by their offspring. Pregnant HIV-1-infected Haitian women were tested for the presence of antibodies against peptides of 14-17 amino acid length from the V3 loop region of strains IIIb
HTLV-I among U.S. Marines stationed in a hyperendemic area: evidence for female-to-male sexual transmission.: J Acquir Immune Defic Syndr. 1992;5(2):158-62. Unique Identifier : AIDSLINE MED/92122103; Brodine SK; Oldfield EC 3d; Corwin AL; Thomas RJ; Ryan AB; Holmberg J; Molgaard CA; Golbeck AL; Ryden LA; Benenson AS; et al; Department of Internal Medicine (Infectious Disease Division),; Naval Hospital, San Diego, CA 92134-5000.; Among 5,255 active duty United States Marines on permanent tour in Okinawa, Japan , screened for human T-cell leukemia/lymphoma virus type I (HTLV-I) seropositivity, 3 (0.06%) were confirmed by Western blot analysis to have core and envelope reactivit
HIV prevalence among intravenous drug users: model-based estimates from New Haven's legal needle exchange.: J Acquir Immune Defic Syndr. 1992;5(2):163-9. Unique Identifier : AIDSLINE MED/92122104; Kaplan EH; Heimer R; Yale School of Organization and Management, New Haven, CT 06520.; The legal needle exchange in New Haven, Connecticut, was signed into law in July 1990. As part of a rigorous effort to evaluate this program, all distributed syringes receive unique tracking codes, and a sample of returned needles are tested for the presence of HIV proviral DNA via polymerase chain reaction. These dat
Alternative confirmatory strategies in HIV-1 antibody testing.: J Acquir Immune Defic Syndr. 1992;5(2):170-6. Unique Identifier : AIDSLINE MED/92122105; Urassa WK; Bredberg-Raden U; Mbena E; Palsson K; Minja E; Lema RA; Pallangyo K; Mhalu FS; Biberfeld G; Department of Microbiology and Immunology, Muhimbili Medical; Centre, University of Dar es Salaam, Tanzania.; Alternatives to confirmation of human immunodeficiency virus (HIV)-1 seropositivity by Western blot analysis were evaluated retrospectively using combinations of six anti-HIV-1 screening assays, including four enzyme-linked immunosorbent assays (ELISA) and two simple tests (a rapid dot immunoassay and an agglutination
Preactivated merocyanine 540 inactivates HIV-1 and SIV: potential therapeutic and blood banking applications.: J Acquir Immune Defic Syndr. 1992;5(2):188-95. Unique Identifier : AIDSLINE MED/92122107; Tran CC; Allan JS; Pervaiz S; Matthews JL; Trevino SR; Gulliya KS; Department of Virology and Immunology, Southwest Foundation for; Biomedical Research, San Antonio, TX 78228-0147.; A novel photodynamic procedure employing preactivated merocyanine 540 (P-MC 540) was assessed for its effectiveness in inactivating human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV). Merocyanine 540 was preactivated by exposure to laser light at 514 nm prior to addition to viruses or
Transgenic mice carrying intact HIV provirus: biological effects and organization of a transgene.: J Acquir Immune Defic Syndr. 1992;5(2):196-203. Unique Identifier : AIDSLINE MED/92122108; Abramczuk JW; Pezen DS; Leonard JM; Monell-Torrens E; Belcher JH; Martin MA; Notkins AL; Laboratory of Oral Medicine, National Institute of Dental; Research, National Institutes of Health, Bethesda, Maryland.; Twelve transgenic founder animals retaining intact copies of the infectious molecular clone of human immunodeficiency virus (HIV)-1 were obtained. All the founders appeared healthy during a 9- to 12-month observation period. However, transgenic offspring of one of the founders (female #13), died within the 1st month o
Contribution of charged amino acids in the CDR2 region of CD4 to HIV-1 gp120 binding.: J Acquir Immune Defic Syndr. 1992;5(2):204-10. Unique Identifier : AIDSLINE MED/92122109; Choe HR; Sodroski J; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, MA 02115.; Several negatively charged amino acids of the human immunodeficiency virus type 1 (HIV-1) gp120 glycoprotein have been implicated in binding to the CD4 viral receptor. The CD4 region implicated in binding gp120 consists of a hydrophobic ridge protruding from a positively charged surface. To examine whether any of the
The first report of HTLV-I infection associated with blood transfusion in a thalassemic patient from Sicily, Italy [letter]: J Acquir Immune Defic Syndr. 1992;5(2):211-2. Unique Identifier : AIDSLINE MED/92122110; Nunnari A; Russo R; Cosentino S; Cacopardo B; Celesia BM; La Rosa R; Nigro L; Saracco A; Lillo F; Varnier OE; et al
Seroprevalence stable and seroconversions rare among injection drug users in Los Angeles [letter]: J Acquir Immune Defic Syndr. 1992;5(2):212-3. Unique Identifier : AIDSLINE MED/92122111; Longshore D; Anglin MD
Structure-activity relationships of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine analogues: effect of substitutions at the C-6 phenyl ring and at the C-5 position on anti-HIV-1 activity.: J Med Chem. 1992 Jan 24;35(2):337-45. Unique Identifier : AIDSLINE MED/92122250; Tanaka H; Takashima H; Ubasawa M; Sekiya K; Nitta I; Baba M; Shigeta S; Walker RT; De Clercq E; Miyasaka T; School of Pharmaceutical Sciences, Showa University, Tokyo,; Japan.; The effect of substitution on the pyrimidine moiety of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)-2-thiothymine (HEPT-S) on anti-HIV-1 activity was investigated by synthesizing a series of 5-methyl-6-(arylthio) and 5-substituted-6-(phenylthio) derivatives. P
Synthesis and biologic activity of 2'-fluoro-2-halo derivatives of 9-beta-D-arabinofuranosyladenine.: J Med Chem. 1992 Jan 24;35(2):397-401. Unique Identifier : AIDSLINE MED/92122259; Montgomery JA; Shortnacy-Fowler AT; Clayton SD; Riordan JM; Secrist JA 3d; Southern Research Institute, Organic Chemistry Research,; Birmingham, Alabama 35255-5305.; The synthesis of 2-halo-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenines (4b and 4d) by coupling the 2,6-dihalopurine with 3-acetyl-5-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide (2) followed by replacement of the 6-halogen with concomitant removal of the acyl blocking groups is described. 2-Fluoroadenine d
Head of 1992 AIDS conference outlines many innovations and new participation [news]: JAMA. 1992 Feb 12;267(6):775-6. Unique Identifier : AIDSLINE MED/92122417; Goldsmith MF
From the Centers for Disease Control. The second 100,000 cases of acquired immunodeficiency syndrome--United States.: JAMA. 1992 Feb 12;267(6):788. Unique Identifier : AIDSLINE MED/92122423
HIV-infected surgeons [letter; comment]: JAMA. 1992 Feb 12;267(6):803; discussion 805. Unique Identifier : AIDSLINE MED/92122425; Burget GC; Orane AM; Teplica D
HIV-infected surgeons [letter]: JAMA. 1992 Feb 12;267(6):803-4; discussion 805. Unique Identifier : AIDSLINE MED/92122426; Halevy A
HIV-infected surgeons [letter; comment]: JAMA. 1992 Feb 12;267(6):804; discussion 805. Unique Identifier : AIDSLINE MED/92122427; Novick A
HIV-infected surgeons [letter; comment]: JAMA. 1992 Feb 12;267(6):804-5. Unique Identifier : AIDSLINE MED/92122428; Isaacman SH
HIV-infected surgeons [letter; comment]: JAMA. 1992 Feb 12;267(6):805. Unique Identifier : AIDSLINE MED/92122429; Yawn BP
Pneumocystis carinii pneumonia among patients without AIDS at a cancer hospital.: JAMA. 1992 Feb 12;267(6):832-7. Unique Identifier : AIDSLINE MED/92122440; Sepkowitz KA; Brown AE; Telzak EE; Gottlieb S; Armstrong D; Infectious Disease Service, Memorial Sloan-Kettering Cancer; Center, Cornell University Medical College, New York, NY 10021.; OBJECTIVES--To determine the predisposing factors, attack rate by underlying disease, and outcome of Pneumocystis carinii pneumonia among patients without the acquired immunodeficiency syndrome (AIDS) at a cancer center. DATA SOURCE--Twelve-year retrospective review from a tertiary-care cancer center. STUDY SELECTION-
Effect of HIV posttest counseling on STD incidence.: JAMA. 1992 Feb 12;267(6):843-5. Unique Identifier : AIDSLINE MED/92122442; Zenilman JM; Erickson B; Fox R; Reichart CA; Hook EW 3d; Johns Hopkins University School of Medicine, Division of; Infectious Diseases, Baltimore, Md.; OBJECTIVE--To evaluate the effectiveness of human immunodeficiency virus (HIV) testing and posttest counseling in reducing subsequent high-risk behavior. METHODS--The incidence of sexually transmitted diseases (STDs) in the Baltimore, Md, public STD clinic population after HIV testing and counseling was determined by
Antifungal agents used for deep-seated mycotic infections.: Mayo Clin Proc. 1992 Jan;67(1):69-91. Unique Identifier : AIDSLINE MED/92122834; Terrell CL; Hughes CE; Division of Infectious Diseases, Mayo Clinic, Rochester, MN; 55905.; The increased use of immunosuppressive regimens in organ transplantation and in the treatment of malignant lesions and the epidemic of acquired immunodeficiency syndrome (AIDS) are major reasons for the greater prevalence of fungal infections seen in clinical practice during the past decade. The traditional cornerston
Failure to detect HTLV-I by in situ hybridization in the biopsied muscles of viral carriers with polymyositis.: Muscle Nerve. 1992 Jan;15(1):43-7. Unique Identifier : AIDSLINE MED/92123270; Higuchi I; Nerenberg M; Yoshimine K; Yoshida M; Fukunaga H; Tajima K; Osame M; Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima University, Japan.; Direct infection of muscle fibers by human T-lymphotropic virus type I (HTLV-I) has recently been reported in a patient with polymyositis infected with both HTLV-I and human immunodeficiency virus (HIV). Coinfections of these viruses are frequently found in the United States . In Kagosh
Treatment of HIV infection--progress in perspective [editorial; comment]: N Engl J Med. 1992 Feb 13;326(7):484-6. Unique Identifier : AIDSLINE MED/92123288; Corey L; Fleming TR
[Frequent side effects of cotrimoxazole in persons infected with HIV, possibly due to metabolites of sulfamethoxazole]: Ned Tijdschr Geneeskd. 1992 Jan 11;136(2):61-3. Unique Identifier : AIDSLINE MED/92123353; van der Ven AJ; Koopmans PP; Vree TB; van der Meer JW; Kliniek voor Inwendige Ziekten, afd. Algemeen Interne; Geneeskunde, Academisch Ziekenhuis St. Radboud, Nijmegen.
[HIV infection in pregnant women in The Netherlands]: Ned Tijdschr Geneeskd. 1992 Jan 11;136(2):80-4. Unique Identifier : AIDSLINE MED/92123358; Mulder-Kampinga GA; Boer K; Scherpbier HJ; Afd. Virologie, Academisch Medisch Centrum, Amsterdam.; A review is given of the pregnant women with HIV infection known to the co-ordinating centre of the Dutch prospective study of HIV seropositive pregnant women and their children . Fifty-five women with 57 pregnancies were discovered between 1 September 1985 and 1 January 1991. Of these women, 60% were not of Dutch or
AIDS: advocacy & activism.: Nurs Health Care. 1992 Jan;13(1):12-3. Unique Identifier : AIDSLINE MED/92123492; Fedor MA
Liability issue related to advising and counseling on health issues.: Nurse Educ. 1992 Jan-Feb;17(1):3-4. Unique Identifier : AIDSLINE MED/92123510; Brooke PS
Cranial MR imaging in HIV-seropositive individuals [letter; comment]: Radiology. 1992 Feb;182(2):583-4. Unique Identifier : AIDSLINE MED/92123922; Reboulot B; Diaine B; Coussement A; Cassuto JP
[Pneumocystis carinii pneumonia in HIV-negative immunosuppressed patients]: Schweiz Med Wochenschr. 1992 Jan 18;122(3):45-54. Unique Identifier : AIDSLINE MED/92124158; Speich R; Hohl M; Hess T; Russi EW; Departement fur Innere Medizin, Medizinische Klinik,; Universitatsspital Zurich.; During a period of 10 years 129 immunosuppressed HIV-negative patients were evaluated for pulmonary complications. A definite diagnosis could be established in 72 cases (56%): Pneumocystis carinii pneumonia (PCP) (25), pulmonary involvement of underlying disease (10), drug toxicity (8), mycobacterioses (6), bacterial
AIDS in South Africa--into the second decade [editorial]: S Afr Med J. 1992 Jan 18;81(2):55-6. Unique Identifier : AIDSLINE MED/92124246; Schoub BD
Statistical approaches to determine the current extent and future prevalence of HIV infection in South Africa [editorial]: S Afr Med J. 1992 Jan 18;81(2):57. Unique Identifier : AIDSLINE MED/92124247; Padayachee GN; Groeneveld H
Children with AIDS--can we afford to treat them?: S Afr Med J. 1992 Jan 18;81(2):61-2. Unique Identifier : AIDSLINE MED/92124250; Hussey G; Robertson A; Beatty D
Estimations of the total size of the HIV and hepatitis B epidemics in South Africa.: S Afr Med J. 1992 Jan 18;81(2):63-6. Unique Identifier : AIDSLINE MED/92124251; Schoub BD; MRC AIDS Virus Research Unit, University of the Witwatersrand,; Johannesburg.; The total number of people infected with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in South Africa was estimated from a number of sources of seroprevalence for each of these viruses. A total figure of 122,951 HIV-infected individuals in South Africa was arrive
A stochastic model for medium-term estimation of the prevalence of HIV infection in a South African heterosexual population [published erratum appears in S Afr Med J 1992 Mar 7;81(5):284]: S Afr Med J. 1992 Jan 18;81(2):67-70. Unique Identifier : AIDSLINE MED/92124252; Groeneveld H; Padayachee N; Department of Statistics, University of Pretoria.; This paper describes the development of a micro-simulation model to estimate the extent of HIV infection among black heterosexual South Africans and attempts to predict the number of newly acquired cases of HIV infection for the period 1985-2000. Owing to the lack of key data inputs, many assumptions are made. The inp
Perceptions and knowledge about AIDS among family planning clinic attenders in Johannesburg.: S Afr Med J. 1992 Jan 18;81(2):71-4. Unique Identifier : AIDSLINE MED/92124253; Govender V; Bhana R; Pillay A; Panchia R; Padayachee GN; de Beer M; Department of Community Health, University of the Witwatersrand,; Johannesburg.; Many studies assessing the impact of national AIDS prevention programmes on knowledge, attitudes and practices have been published world-wide. Most have found that, while general knowledge increased, there was little change in behaviour. A survey of a random sample of 50 women attending a family planning clinic in Joh
Sexually transmitted disease surveillance in a child abuse clinic.: S Afr Med J. 1992 Jan 18;81(2):84-6. Unique Identifier : AIDSLINE MED/92124257; de Villiers FP; Prentice MA; Bergh AM; Miller SD; Child Abuse Clinic, Transvaal Memorial Institute for Child; Health, Johannesburg.; The sexually transmitted disease surveillance system instituted at the Child Abuse and Neglect (CAN) clinic of the Transvaal Memorial Institute for Child Health and Development was evaluated after 1 year. The presenting complaint of the vast majority of the 227 patients was sexual abuse. In more than half (52%), child
Immunization with tween-ether-treated SIV adsorbed onto aluminum hydroxide protects monkeys against experimental SIV infection.: Virology. 1992 Feb;186(2):588-96. Unique Identifier : AIDSLINE MED/92124733; Stahl-Hennig C; Voss G; Nick S; Petry H; Fuchs D; Wachter H; Coulibaly C; Luke W; Hunsmann G; Deutsches Primatenzentrum, Abteilung Virologie und Immunologie,; Gottingen, Germany.; In order to examine the efficiency of an AIDS vaccine potentially acceptable for human use we have investigated a split vaccine. Since such vaccines are safe and efficient, they have been in use for many years to protect man against enveloped RNA viruses, e.g., influenza and measles. Seven rhesus monkeys were immunize
DNA sequence analysis of the gene encoding the HTLV-I p21e transmembrane protein reveals inter- and intraisolate genetic heterogeneity.: Virology. 1992 Feb;186(2):619-27. Unique Identifier : AIDSLINE GENBANK; Ehrlich GD; Andrews J; Sherman MP; Greenberg SJ; Poiesz BJ; Department of Pathology, University of Pittsburgh, Pennsylvania; 15261.; DNA sequence analysis was performed on a 235-bp region of the p21 e transmembrane protein gene of the human T-cell lymphoma/leukemia virus type I (HTLV-I) which encompassess the putative immunosuppressive peptide. Polymerase chain reaction-based amplification was used to generate multiple molecular clones from isolate
HIV1 cytopathogenicity-genetic difference between direct cytotoxic and fusogenic effect.: Virology. 1992 Feb;186(2):647-54. Unique Identifier : AIDSLINE MED/92124739; Hirsch I; Salaun D; Brichacek B; Chermann JC; Unite de Recherches INSERM U322 sur les Retrovirus et Maladies; Associees, Marseille, France.; Formation of large syncytia, rapid cell killing, and early onset of replication are characteristics of the highly cytopathic Zairian virus strain HIV1 NDK compared with the HIV1 LAV prototype. Recombinant provirus molecules derived from cloned infectious DNAs of HIV1 LAV and NDK were constructed by reciprocal exchange
Myb protein binds to multiple sites in the human T cell lymphotropic virus type 1 long terminal repeat and transactivates LTR-mediated expression.: Virology. 1992 Feb;186(2):764-9. Unique Identifier : AIDSLINE MED/92124752; Bosselut R; Lim F; Romond PC; Frampton J; Brady J; Ghysdael J; Laboratoire d'Oncologie Virale et Cellulaire, CNRS URA 1443,; Institut Curie, Orsay, France.; The members of the c-myb proto-oncogene family encode sequence-specific transcriptional activators. In T cells, expression of c-myb and the related B-myb gene is induced following mitogenic stimulation. Using a purified recombinant protein, we report here that the human T cell lymphotropic virus type 1 (HTLV-1) LTR c
SIV from stump-tailed macaques: molecular characterization of a highly transmissible primate lentivirus.: Virology. 1992 Feb;186(2):783-7. Unique Identifier : AIDSLINE GENBANK/M83293; Novembre FJ; Hirsch VM; McClure HM; Fultz PN; Johnson PR; Department of Microbiology, Georgetown University, Rockville,; Maryland 20852.; Over the past 6 years, simian immunodeficiency viruses (SIVs) have been isolated from four distinct species of macaques (Macaca mulatta, M. fascicularis, M. nemestrina, and M. arctoides) in captivity in the United States . However, the epidemiologic and genetic relationships among SIVs
Cognitive and motor development in infants at risk for human immunodeficiency virus.: Am J Dis Child. 1992 Feb;146(2):218-22. Unique Identifier : AIDSLINE MED/92125295; Aylward EH; Butz AM; Hutton N; Joyner ML; Vogelhut JW; Department of Psychiatry and Behavioral Sciences, Johns Hopkins; University Medical Institutions, Baltimore, Md.; To evaluate the natural course of cognitive and motor development among infants infected with human immunodeficiency virus from birth, the Bayley Scales of Infant Development were administered to 96 infants between 5.5 and 24 months of age. Infants were divided into three groups on the basis of subsequent assessment o
Low-dose splenic irradiation in the treatment of autoimmune thrombocytopenia in HIV-infected patients.: Ann Intern Med. 1992 Feb 15;116(4):310-1. Unique Identifier : AIDSLINE MED/92125694; Needleman SW; Sorace J; Poussin-Rosillo H; University of Maryland Hospital, Baltimore.
Cardiomyopathy associated with antiretroviral therapy in patients with HIV infection: a report of six cases.: Ann Intern Med. 1992 Feb 15;116(4):311-3. Unique Identifier : AIDSLINE MED/92125695; Herskowitz A; Willoughby SB; Baughman KL; Schulman SP; Bartlett JD; Johns Hopkins Hospital, School of Public Health and Hygiene,; Baltimore.
Predictors of mortality among HIV-infected women in Kigali, Rwanda.: Ann Intern Med. 1992 Feb 15;116(4):320-8. Unique Identifier : AIDSLINE MED/92125697; Lindan CP; Allen S; Serufilira A; Lifson AR; Van de Perre P; Chen-Rundle A; Batungwanayo J; Nsengumuremyi F; Bogaerts J; Hulley S; Center for AIDS Prevention Studies, University of California at; San Francisco.; OBJECTIVE: To better characterize the natural history of disease due to human immunodeficiency virus (HIV) infection in African women. DESIGN: Prospective cohort study over a 2-year follow-up period. PARTICIPANTS: A total of 460 HIV-seropositive women and a comparison cohort of HIV-seronegative women recruited from pr
Syphilis and AIDS in Belle Glade, Florida, 1942 and 1992 [see comments]: Ann Intern Med. 1992 Feb 15;116(4):329-34. Unique Identifier : AIDSLINE MED/92125698; Grey MR; Occupational Medicine Program, University of Connecticut Health; Center, Farmington 06030.
HIV in Africa: what is the future? [editorial] [see comments]: Ann Intern Med. 1992 Feb 15;116(4):339-41. Unique Identifier : AIDSLINE MED/92125700; Berkley S
The lessons of Belle Glade [editorial; comment]: Ann Intern Med. 1992 Feb 15;116(4):343-4. Unique Identifier : AIDSLINE MED/92125702; Swenson RM
Pathology of pentamidine-induced pancreatitis.: Arch Pathol Lab Med. 1992 Feb;116(2):162-4. Unique Identifier : AIDSLINE MED/92125925; Klatt EC; Department of Laboratories and Pathology, LAC-USC Medical Center.; Extensive acute necrotizing pancreatitis occurred in three patients with the acquired immunodeficiency syndrome who had received both aerosolized pentamidine as prophylaxis and intravenous pentamidine for Pneumocystis carinii pneumonia. The clinical manifestations along with gross and microscopic pathologic findings a
Vaccination with gp160 in HIV [letter; comment]: N Engl J Med. 1992 Jan 30;326(5):347; discussion 348. Unique Identifier : AIDSLINE MED/92100159; Seligman SJ
A human issue [letter; comment]: Nurs Health Care. 1992 Jan;13(1):8. Unique Identifier : AIDSLINE MED/92123498; Morgan DO
Effect of triiodothyronine on the expression of T cell markers and immune function in thyroidectomized White Leghorn chickens.: Proc Soc Exp Biol Med. 1992 Jan;199(1):104-13. Unique Identifier : AIDSLINE MED/92093981; Johnson BE; Marsh JA; King DB; Lillehoj HS; Scanes CG; Department of Microbiology, Immunology, and Parasitology, College; of Veterinary Medicine, Cornell University, Ithaca, New York; 14853.; Hypothyroid K-strain chickens were produced by neonatal thyroidectomy and treatment with 6-propyl-2-thiouracil. Thyroidectomized birds were given 0, 1.5, 4.5, 15, or 45 micrograms/kg body wt of triiodothyronine (T3) by daily injection. At 5 weeks of age, thymocytes were prepared for flow cytometric analysis of CT-1a,
Desensitization to dapsone in HIV-positive patients [letter]: JAMA. 1992 Jan 22-29;267(4):512. Unique Identifier : AIDSLINE MED/92106463; Metroka CE; Lewis NJ; Jacobus DP
OSHA stiffens bloodborne rules, decrees free hepatitis B vaccine [news]: Am J Nurs. 1992 Jan;92(1):82-4. Unique Identifier : AIDSLINE MED/92109267
Abnormal immune adherence and elimination of hepatitis B surface antigen/antibody complexes in patients with AIDS.: J Immunol. 1992 Feb 1;148(3):723-8. Unique Identifier : AIDSLINE MED/92113251; Madi N; Steiger G; Estreicher J; Schifferli JA; Departement de Medecine, Hopital Cantonal Universitaire,; Geneva, Switzerland.; C3b-coated immune complexes (IC) adhere to complement receptor 1 (CR1) on human E in the circulation. E from AIDS patients have an acquired low CR1 number. To study immune adherence and IC elimination in AIDS, radiolabeled hepatitis B surface Ag/antibody complexes were injected i.v. in six AIDS patients and in 14 heal
Enhancement of in vitro and in vivo antigen-specific antibody responses by interleukin 11.: J Exp Med. 1992 Jan 1;175(1):211-6. Unique Identifier : AIDSLINE MED/92113461; Yin TG; Schendel P; Yang YC; Department of Medicine, Indiana University School of Medicine,; Indianapolis 46202.; The availability of large quantities of highly purified recombinant interleukin 11 (rhuIL-11) has allowed us to investigate the effects of rhuIL-11 on sheep red blood cell (SRBC)-specific antibody responses in the murine system. The results showed that rhuIL-11 was effective in enhancing the generation of mouse spleen
Human T-cell leukemia virus type I envelope protein maturation process: requirements for syncytium formation.: J Virol. 1992 Feb;66(2):906-13. Unique Identifier : AIDSLINE MED/92114194; Pique C; Pham D; Tursz T; Dokhelar MC; CNRS UA 1156, Institut Gustave Roussy, Villejuif, France.; The human T-cell leukemia virus type I (HTLV-I) envelope protein is synthesized as a gp61 precursor product cleaved into two mature proteins, a gp45 exterior protein and a gp20 anchoring the envelope at the cell membrane. Using N-glycosylation inhibitors and site-directed mutagenesis of the potential glycosylation sit
Follicular dendritic cells are a major reservoir for human immunodeficiency virus type 1 in lymphoid tissues facilitating infection of CD4+ T-helper cells.: Am J Pathol. 1992 Jan;140(1):15-22. Unique Identifier : AIDSLINE MED/92117074; Spiegel H; Herbst H; Niedobitek G; Foss HD; Stein H; Institute of Pathology, Klinikum Steglitz, Free University; Berlin, Federal Republic of Germany.; Human immunodeficiency virus type 1 (HIV-1) infection causes progressive depletion of CD4/HIV-receptor-positive T helper lymphocytes, ultimately leading to AIDS. The major HIV reservoir and site of T-helper cell infection in lymphoid tissues, however, has remained poorly defined. The authors used in situ hybridization
Endothelial cell dysfunction in HIV infection.: J Acquir Immune Defic Syndr. 1992;5(2):127-31. Unique Identifier : AIDSLINE MED/92122097; Lafeuillade A; Alessi MC; Poizot-Martin I; Boyer-Neumann C; Zandotti C; Quilichini R; Aubert L; Tamalet C; Juhan-Vague I; Gastaut JA; CISIH, Hopital Salvator, Marseille, France.; We have investigated plasma levels of endothelial cell products playing a role in hemostasis in 125 HIV-positive patients and 30 controls. Antigenic von Willebrand factor increased significantly with disease progression and was closely correlated with CD4+ cell counts and beta 2-microglobulin levels. Tissue-type plasm
Parathyroid hormone-related protein binding to human T-cell lymphotropic virus type I-infected lymphocytes.: Endocrinology. 1992 Jan;130(1):300-6. Unique Identifier : AIDSLINE MED/92090329; McCauley LK; Rosol TJ; Merryman JI; Capen CC; Department of Veterinary Pathobiology, Ohio State University,; Columbus 43210.; An HTLV-I-infected human lymphocyte line (MT-2) was evaluated for 1) the presence of receptors for PTH-related protein (PTHrP), 2) cell proliferation in response to PTHrP, and 3) adrenylate cyclase and intracellular calcium response to PTHrP. PTHrP-(1-36) was labeled with 125I, purified, and used to detect binding to
Cytomegalovirus infection of the appendix in AIDS [letter; comment]: Gastroenterology. 1992 Jan;102(1):379-80. Unique Identifier : AIDSLINE MED/92090661; Lauwers GY
Subclinical varicella-zoster virus viremia, herpes zoster, and T lymphocyte immunity to varicella-zoster viral antigens after bone marrow transplantation.: J Infect Dis. 1992 Jan;165(1):119-26. Unique Identifier : AIDSLINE MED/92091858; Wilson A; Sharp M; Koropchak CM; Ting SF; Arvin AM; Department of Pediatrics, Stanford University School of Medicine,; CA 94305.; Bone marrow transplant (BMT) recipients were evaluated for subclinical varicella-zoster virus (VZV) viremia and symptoms of herpes zoster after transplantation. Viremia was demonstrated by testing peripheral blood mononuclear cells using polymerase chain reaction and was documented in 19% of 37 patients. When reactiva
Impact of Pneumocystis carinii and cytomegalovirus on the course and outcome of atypical pneumonia in advanced human immunodeficiency virus disease.: J Infect Dis. 1992 Jan;165(1):93-8. Unique Identifier : AIDSLINE MED/92091889; Bozzette SA; Arcia J; Bartok AE; McGlynn LM; McCutchan JA; Richman DD; Spector SA; Division of Infectious Diseases, UCSD Medical Center 92103-8208.; Patients undergoing bronchoscopy for possible pneumocystis pneumonia were studied retrospectively to characterize the impact of common viral pathogens on the course of advanced human immunodeficiency virus (HIV) disease and atypical pneumonia. In 327 episodes, Pneumocystis carinii was found in 220 (67%),
Extension of public comment period for revision of HIV infection classification system and expansion of AIDS surveillance case definition.: MMWR Morb Mortal Wkly Rep. 1992 Jan 3;40(51-52):891. Unique Identifier : AIDSLINE MED/92092947
The treatment of cytomegalovirus in AIDS--more than meets the eye [editorial; comment]: N Engl J Med. 1992 Jan 23;326(4):264-6. Unique Identifier : AIDSLINE MED/92093037; Hirsch MS
Simultaneous herpes simplex types 1 and 2 keratitis in acquired immunodeficiency syndrome [letter]: Am J Ophthalmol. 1992 Jan 15;113(1):102-3. Unique Identifier : AIDSLINE MED/92095334; Rosenwasser GO; Greene WH
Repair of retinitis-related retinal detachments with silicone oil in patients with acquired immunodeficiency syndrome.: Am J Ophthalmol. 1992 Jan 15;113(1):21-7. Unique Identifier : AIDSLINE MED/92095345; Regillo CD; Vander JF; Duker JS; Fischer DH; Belmont JB; Kleiner R; Retina Service, Wills Eye Hospital, Thomas Jefferson University,; Philadelphia, Pennsylvania.; To provide prompt visual rehabilitation and to reduce the need for repeated operations, we performed vitrectomy with silicone oil tamponade in 16 consecutive eyes with retinal detachments related to cytomegalovirus retinitis and acute retinal necrosis in 13 patients with acquired i
Epstein-Barr virus induced lymphoproliferative tumors in severe combined immunodeficient mice are oligoclonal.: Blood. 1992 Jan 1;79(1):173-9. Unique Identifier : AIDSLINE MED/92096602; Pisa P; Cannon MJ; Pisa EK; Cooper NR; Fox RI; Department of Immunology, Scripps Clinic and Research Foundation,; La Jolla, CA 92037.; Severe combined immunodeficient (SCID) mice reconstituted with lymphocytes from Epstein-Barr virus (EBV) negative human donors develop aggressive tumors after the chimeric mice are infected with EBV. The tumors were composed of human B cells that expressed EBV encoded antigens (latent membrane protein and EBV nuclear
Genital papillomavirus infection and cervical dysplasia--opportunistic complications of HIV infection.: Int J Cancer. 1992 Jan 2;50(1):45-8. Unique Identifier : AIDSLINE MED/92098208; Laga M; Icenogle JP; Marsella R; Manoka AT; Nzila N; Ryder RW; Vermund SH; Heyward WL; Nelson A; Reeves WC; Center for Infectious Diseases, Centers for Disease Control,; Atlanta, GA 30333.; Certain human genital papillomaviruses (HPV) are strongly associated with cervical dysplasia and cancer. Evidence is accumulating that HPV infection and ano-genital cancers are more common in patients with the acquired immunodeficiency syndrome. The objective of our study was to evaluate the extent to which HPV infect
Foscarnet.: Med Lett Drugs Ther. 1992 Jan 10;34(861):3-4. Unique Identifier : AIDSLINE MED/92099939
Special reports on awareness of AIDS and HIV among racial and ethnic minority groups.: MMWR Morb Mortal Wkly Rep. 1992 Jan 17;41(2):30. Unique Identifier : AIDSLINE MED/92100046
New antibiotics look good against M. avium [news]: Am J Nurs. 1992 Jan;92(1):12. Unique Identifier : AIDSLINE MED/92109255
Agency abandons HIV-related list.: Am Nurse. 1992 Jan;24(1):3. Unique Identifier : AIDSLINE MED/92109372
Follicular dendritic cell-B cell interactions in virus disease. Common localization but different cell damage caused by antibody immobilized virus?: Arch Virol. 1992;122(1-2):215-8. Unique Identifier : AIDSLINE MED/92109573; van Rooijen N; Department of Cell Biology, Free University, Amsterdam, The; Netherlands.; Follicular dendritic cells (FDC) are involved in the trapping and retention of antigen-antibody complexes in lymphoid follicles. This FDC immobilized antigen is thought to be involved in the generation of memory B-lymphocytes. Follicular trapping of both Aleutian disease virus and HIV particles has been demonstrated.
Pentoxifylline in treatment of acquired immunodeficiency syndrome? [letter; comment]: Blood. 1992 Jan 15;79(2):535-6. Unique Identifier : AIDSLINE MED/92110594; Ambrus JL; Lillie MA
Pristane induced gene activation.: Chem Biol Interact. 1992 Jan;81(1-2):119-30. Unique Identifier : AIDSLINE MED/92110860; Garrett LR; Jones CJ; Cuchens MA; Department of Microbiology University of Mississippi Medical; Center, Jackson 39216-4505.; Studies were performed to examine the effects of 2,6,10,14-tetramethyl pentadecane (pristane) versus 12-O-tetradecanoylphorbol 13-acetate (TPA) on the activation of the CAT gene under the regulatory control of viral promoter/enhancer elements transfected into NIH-3T3, CV-1 and COS-7 cells. The results of these studies
Didanosine and foscarnet marketed for use by patients with AIDS [news]: Clin Pharm. 1992 Jan;11(1):4, 6. Unique Identifier : AIDSLINE MED/92111099
Herpes simplex virus infection as a risk factor for human immunodeficiency virus infection in heterosexuals [see comments]: J Infect Dis. 1992 Feb;165(2):251-5. Unique Identifier : AIDSLINE MED/92113329; Hook EW 3d; Cannon RO; Nahmias AJ; Lee FF; Campbell CH Jr; Glasser D; Quinn TC; Division of Infectious Diseases, Johns Hopkins University School; of Medicine, Baltimore, MD 21205.; To determine if infection with herpes simplex virus (HSV) type 2 is associated with human immunodeficiency virus (HIV) type 1 infection among patients attending sexually transmitted diseases clinics, a case-control study was done on coded sera from 179 HIV-1-infected patients and 367 age-, race-, and gender-matched HI
Role of Epstein-Barr virus and interleukin 6 in the development of lymphomas of human origin in SCID mice engrafted with human tonsillar mononuclear cells.: J Gen Virol. 1992 Jan;73 ( Pt 1):113-21. Unique Identifier : AIDSLINE MED/92113559; Nadal D; Albini B; Schlapfer E; Bernstein JM; Ogra PL; Departments of Pediatrics, State University of New York, Buffalo; School of Medicine and Biomedical Sciences.; Mice with severe combined immunodeficiency were inoculated intraperitoneally with 50 x 10(6) human tonsillar mononuclear cells (hu-TMCs) from Epstein-Barr virus (EBV) antibody seropositive or seronegative human subjects. Between 5 and 11 weeks later, 29.4% (10/34) of mice injected with hu-TMCs from EBV seropositive do
Characterization of early pathogenic effects after experimental infection of calves with bovine immunodeficiency-like virus.: J Virol. 1992 Feb;66(2):1074-83. Unique Identifier : AIDSLINE MED/92114129; Carpenter S; Miller LD; Alexandersen S; Whetstone CA; VanDerMaaten MJ; Viuff B; Wannemuehler Y; Miller JM; Roth JA; Department of Microbiology, Immunology and Preventive Medicine,; College of Veterinary Medicine, Iowa State University, Ames; 50011.; The early pathogenic effects of bovine immunodeficiency-like virus (BIV) were studied in calves experimentally inoculated with BIV. All animals inoculated with BIV R29-infected cells seroconverted by 6 weeks postinoculation, and BIV was recoverable from each animal at 2 weeks postinoculation. However, levels of BIV re
Isolation and partial characterization of infectious molecular clones of feline immunodeficiency virus obtained directly from bone marrow DNA of a naturally infected cat.: J Virol. 1992 Feb;66(2):1091-7. Unique Identifier : AIDSLINE GENBANK/M73965; Siebelink KH; Chu IH; Rimmelzwaan GF; Weijer K; Osterhaus AD; Bosch ML; Laboratory of Immunobiology, National Institute of Public Health; and Environmental Protection, Bilthoven, The Netherlands.; Replication-competent molecular clones of feline immunodeficiency virus (FIV) were isolated directly from the DNA of bone marrow cells of a naturally FIV-infected cat. After transfection in a feline kidney cell line (CrFK) and subsequent cocultivation with peripheral blood mononuclear cells (PBMC), the viral progeny o
Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virus.: J Virol. 1992 Feb;66(2):1219-22. Unique Identifier : AIDSLINE MED/92114149; Takeuchi Y; Vile RG; Simpson G; O'Hara B; Collins MK; Weiss RA; Chester Beatty Laboratories, Institute of Cancer Research,; London, England.; Pseudotypes of gibbon ape leukemia virus/simian sarcoma-associated virus (GALV/SSAV) and feline leukemia virus subgroup B (FeLV-B) have been constructed by rescuing a Moloney murine leukemia virus vector genome with wild-type GALV/SSAV or FeLV-B. The resulting recombinant viruses utilized core and envelope proteins fr
In vitro resolution of adeno-associated virus DNA hairpin termini by wild-type Rep protein is inhibited by a dominant-negative mutant of rep.: J Virol. 1992 Feb;66(2):1236-40. Unique Identifier : AIDSLINE MED/92114153; Owens RA; Carter BJ; Laboratory of Molecular and Cellular Biology, National Institute; of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland; 20892.; An adeno-associated virus (AAV) genome with a Lys-to-His (K340H) mutation in the consensus nucleotide triphosphate binding site of the rep gene has a dominant-negative DNA replication phenotype in vivo. We expressed both wild-type (Rep78) and mutant (Rep78NTP) proteins in two helper-free expression systems consisting
v-mos proteins encoded by myeloproliferative sarcoma virus and its ts159 mutant.: J Virol. 1992 Feb;66(2):1267-72. Unique Identifier : AIDSLINE MED/92114158; Singh B; Stocking C; Walker R; Yang YD; Ostertag W; Arlinghaus RB; Department of Molecular Pathology, University of Texas M.D.; Anderson Cancer Center, Houston 77030.; The myeloproliferative sarcoma virus (MPSV) v-mos protein was predicted to be identical in size to p39c-mos because of an observed one-base deletion in the seventh codon of the env-mos open reading frame, which would allow translation to initiate at the methionine equivalent to codon 32 of the env-mos gene. On the bas
A cyclic AMP-responsive DNA-binding protein (CREB2) is a cellular transactivator of the bovine leukemia virus long terminal repeat.: J Virol. 1992 Feb;66(2):766-72. Unique Identifier : AIDSLINE MED/92114179; Willems L; Kettmann R; Chen G; Portetelle D; Burny A; Derse D; Faculty of Agronomy, Gembloux, Belgium.; To gain insight into the cellular regulation of bovine leukemia virus (BLV) trans activation, a lambda-gt11 cDNA library was constructed with mRNA isolated from a BLV-induced tumor and the recombinant proteins were screened with an oligonucleotide corresponding to the tax activation-responsive element (TAR). Two clone
Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C.: J Virol. 1992 Feb;66(2):983-91. Unique Identifier : AIDSLINE MED/92114203; Lucito R; Schneider RJ; Department of Biochemistry, New York University Medical Center,; New York 10016.; The hepatitis B virus X protein stimulates transcription from a variety of promoter elements, including those activated by transcription factor NF-kappa B. A diverse group of extra- and intracellular agents, including growth factors and the human immunodeficiency virus tat protein, have been shown to require a functio
Peripheral neuropathy induced by 2',3'-dideoxycytidine. A rabbit model of 2',3'-dideoxycytidine neurotoxicity.: Lab Invest. 1992 Jan;66(1):63-74. Unique Identifier : AIDSLINE MED/92114499; Anderson TD; Davidovich A; Arceo R; Brosnan C; Arezzo J; Schaumburg H; Department of Toxicology and Pathology, Hoffmann-La Roche Inc.,; Nutley, New Jersey.; The nucleoside analog 2 ,3 -dideoxycytidine ( ddC ) is a potent inhibitor of the reverse transcriptase of human immunodeficiency virus and a DNA chain terminator. In clinical trials in patients with acquired immunodeficiency syndrome, ddC treatment has
Ultrastructure of peripheral neuropathy induced in rabbits by 2',3'-dideoxycytidine.: Lab Invest. 1992 Jan;66(1):75-85. Unique Identifier : AIDSLINE MED/92114500; Feldman D; Brosnan C; Anderson TD; Department of Toxicology and Pathology, Hoffmann-La Roche Inc.,; Nutley, New Jersey.; The nucleoside analogue, 2 ,3 -dideoxycytidine ( ddC ), an inhibitor of human immunodeficiency virus reverse transcriptase, mediates virologic and immunologic improvements in acquired immunodeficiency syndrome patients. However, in clinical studies ddC
Immunosuppressive effects of corticotropin and melanotropin and their possible significance in human immunodeficiency virus infection.: Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):782-6. Unique Identifier : AIDSLINE MED/92115745; Smith EM; Hughes TK Jr; Hashemi F; Stefano GB; Department of Psychiatry, University of Texas Medical Branch,; Galveston 77550.; The activation of human granulocytes and invertebrate immunocytes was found to be suppressed by corticotropin (ACTH) and melanotropin (MSH). In spontaneously active granulocytes both neuropeptides caused significant conformational changes indicative of inactivity plus a reduction in their locomotion. Significant inact
HIV and health care providers: to test or not to test.: Tex Nurs. 1992 Jan;66(1):8-9. Unique Identifier : AIDSLINE MED/92116382; Halloran JP
Expression of feline immunodeficiency virus gag gene in Escherichia coli.: Arch Virol. 1992;122(3-4):383-90. Unique Identifier : AIDSLINE MED/92117876; Furuya T; Hasegawa A; Saitoh M; Miyazawa T; Tohya Y; Hayami M; Takahashi E; Miki K; Mikami T; Department of Veterinary Microbiology, Faculty of Agriculture,; University of Tokyo, Japan.; The gag gene of a Japanese feline immunodeficiency virus (FIV) isolate, designated as FIV TM 2, was expressed in Escherichia coli as a fusion protein with TrpE. Using this expressed protein, an enzyme-linked immunosorbent assay was developed for detection of antibodies to FIV gag protein in feline sera. With serum sam
Solvent/detergent-treated plasma: a virus-inactivated substitute for fresh frozen plasma.: Blood. 1992 Feb 1;79(3):826-31. Unique Identifier : AIDSLINE MED/92119309; Horowitz B; Bonomo R; Prince AM; Chin SN; Brotman B; Shulman RW; New York Blood Center, New York 10021.; Fresh frozen plasma (FFP) is prepared in blood banks world-wide as a by-product of red blood cell concentrate preparation. Appropriate clinical use is for coagulation factor disorders where appropriate concentrates are unavailable and when multiple coagulation factor deficits occur such as in surgery. Viral safety dep
Identification and analysis of the gag-pol ribosomal frameshift site of feline immunodeficiency virus.: Virology. 1992 Feb;186(2):389-97. Unique Identifier : AIDSLINE GENBANK/X57002; Morikawa S; Bishop DH; AIDS Research Center, National Institute of Health, Tokyo, Japan.; The pol genes of retroviruses are translated as gag-pol fusion proteins by ribosomal frameshifting within the gag-pol overlap region. During the ribosomal frameshift event, the gag open reading frame is shifted -1 nt to allow in-phase reading of the pol open reading frame. A consensus frameshift signal sequence of GGG
Expression of bovine immunodeficiency-like virus envelope glycoproteins by a recombinant baculovirus in insect cells [published erratum appears in Virology 1992 Jun;188(2):959]: Virology. 1992 Feb;186(2):551-61. Unique Identifier : AIDSLINE MED/92124729; Rasmussen L; Greenwood JD; Gonda MA; Laboratory of Cell and Molecular Structure, National Cancer; Institute-Frederick Cancer Research and Development Center,; Maryland 21702-1201.; The bovine immunodeficiency-like virus (BIV) env open reading frame (ORF) contains both sequences encoding env and sequences for exon 1 of the putative rev gene. Recombinant baculoviruses incorporating BIV env ORF sequences were constructed to characterize the expression, processing, and immunogenicity of products of
Genomic organization and expression of simian foamy virus type 3 (SFV-3).: Virology. 1992 Feb;186(2):597-608. Unique Identifier : AIDSLINE GENBANK/M74895; Renne R; Friedl E; Schweizer M; Fleps U; Turek R; Neumann-Haefelin D; Abteilung Virologie, Universitat Freiburg, Germany.; The complete nucleotide sequence of simian foamy virus type 3 (SFV-3) strain LK-3, isolated from an African green monkey, was determined. In addition to translation frames representing the gag, pol, and env genes, two open reading frames are located in the region between the env gene and the 3 long terminal repeat (L
Transactivation of the HIV-1 LTR by HSV-1 immediate-early genes.: Virology. 1992 Feb;186(2):788-91. Unique Identifier : AIDSLINE MED/92124756; Margolis DM; Rabson AB; Straus SE; Ostrove JM; Medical Virology Section, NIAID, NIH, Bethesda, Maryland 20892.; Herpes simplex virus type 1 (HSV-1) activates transcription from the long terminal repeat (LTR) promoter region of the human immunodeficiency virus type 1 (HIV-1). HSV-1 immediate-early (IE) genes ICP0 and ICP4 are thought to be important mediators of this process, which is known to involve the induction of the cellul
The HIV-infected health care worker: another AIDS policy conundrum [editorial]: Ann Intern Med. 1992 Feb 15;116(4):341-3. Unique Identifier : AIDSLINE MED/92125701; Scott HD
From the eye of the storm, with the eyes of a physician [see comments]: Ann Intern Med. 1992 Feb 15;116(4):335-8. Unique Identifier : AIDSLINE MED/92125699; Aoun H
CD4+ subset regulation in viral infection. Preferential activation of Th2 cells during progression of retrovirus-induced immunodeficiency in mice.: J Immunol. 1992 Jan 1;148(1):182-8. Unique Identifier : AIDSLINE MED/92091770; Gazzinelli RT; Makino M; Chattopadhyay SK; Snapper CM; Sher A; Hugin AW; Morse HC 3d; Laboratory of Parasitic Diseases, National Institute of Allergy; and Infectious Diseases, National Institutes of Health, Bethesda,; MD 20892.; Progressive lymphoproliferation and increasingly severe immunodeficiency are prominent features of a syndrome, designated mouse AIDS, which develops in susceptible strains of mice infected with the mixture of murine leukemia viruses, termed LP-BM5. Development of splenomegaly and lymphadenopathy, caused primarily by i
Absence of infectious human immunodeficiency virus type 1 in natural eccrine sweat.: J Infect Dis. 1992 Jan;165(1):155-8. Unique Identifier : AIDSLINE MED/92091866; Wormser GP; Bittker S; Forseter G; Hewlett IK; Argani I; Joshi B; Epstein JS; Bucher D; Division of Infectious Diseases, New York Medical College,; Westchester County Medical Center, Valhalla 10595.; Although human immunodeficiency virus type 1 (HIV-1) has been found in numerous body fluids, there are no reports of attempts to demonstrate this virus in eccrine sweat, a fluid frequently encountered during person-to-person interactions. Natural eccrine sweat samples and blood from 50 HIV-1-seropositive patients and
Abnormalities of morning serum cortisol levels and circadian rhythms of CD4+ lymphocyte counts in human immunodeficiency virus type 1-infected adult patients [letter]: J Infect Dis. 1992 Jan;165(1):185-6. Unique Identifier : AIDSLINE MED/92091877; Malone JL; Oldfield EC 3d; Wagner KF; Simms TE; Daly R; O'Brian J; Burke DS
Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis. Studies of Ocular Complications of AIDS Research Group, in collaboration with the AIDS Clinical Trials Group [published erratum appears in N Engl J Med 1992 Apr 23;326(17):1172] [see comments]: N Engl J Med. 1992 Jan 23;326(4):213-20. Unique Identifier : AIDSLINE MED/92093029; BACKGROUND AND METHODS. We performed a multicenter, randomized, unblinded clinical trial (the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial) designed to compare ganciclovir with foscarnet in the treatment of cytomegalovirus retinitis in patients with the acquired immunodefi
An outbreak of tuberculosis with accelerated progression among persons infected with the human immunodeficiency virus. An analysis using restriction-fragment-length polymorphisms.: N Engl J Med. 1992 Jan 23;326(4):231-5. Unique Identifier : AIDSLINE MED/92093032; Daley CL; Small PM; Schecter GF; Schoolnik GK; McAdam RA; Jacobs WR Jr; Hopewell PC; Medical Service, San Francisco General Hospital Medical Center,; Calif.; BACKGROUND. Tuberculosis typically develops from a reactivation of latent infection. Clinical tuberculosis may also arise from a primary infection, and this is thought to be more likely in persons infected with the human immunodeficiency virus (HIV). However, the relative importance of these two pathogenetic mechanism
Retinal microvasculopathy and reduced cerebral blood flow in patients with acquired immunodeficiency syndrome [letter]: Am J Ophthalmol. 1992 Jan 15;113(1):100-1. Unique Identifier : AIDSLINE MED/92095333; Geier SA; Schielke E; Klauss V; Muller A; Einhaupl KM; Goebel FD; Tatsch K
Comparative biological responses of rabbits infected with human T-lymphotropic virus type I isolates from patients with lymphoproliferative and neurodegenerative disease.: Int J Cancer. 1992 Jan 2;50(1):124-30. Unique Identifier : AIDSLINE MED/92098195; Lairmore MD; Roberts B; Frank D; Rovnak J; Weiser MG; Cockerell GL; Centers For Disease Control, Division of Viral and Rickettsial; Diseases, Atlanta, GA.; An experimental rabbit model was used to determine host responses to infection by various human T-lymphotropic virus type-I (HTLV-I) strains. Seven groups of 4 to 5 rabbits each were inoculated with lethally-irradiated HTLV-I-infected cell lines derived from patients with adult T-cell leukemia/lymphoma or from patient
Determinants of HIV disease progression [letter; comment]: Lancet. 1992 Jan 11;339(8785):130. Unique Identifier : AIDSLINE MED/92099749; Pizzolo G; Vinante F; Morosato L; De Sabata D; Sinicco A; Raiteri R; Agostini C; Semenzato G
Reducing HIV transmission by seronegative blood [letter; comment] [see comments]: Lancet. 1992 Jan 11;339(8785):130-1. Unique Identifier : AIDSLINE MED/92099750; Zangerle R; Schonitzer D; Fuchs D; Most J; Dierich MP; Wachter H
In-vitro activity of zidovudine against mycoplasma [letter] [see comments]: Lancet. 1992 Jan 11;339(8785):131. Unique Identifier : AIDSLINE MED/92099751; Lafeuillade A; Papierok G; Pautrat G; Escarguel C; Pellegrino P; Quilichini R
HIV-1 sensitivity to zidovudine and clinical outcome in children.: Lancet. 1992 Jan 4;339(8784):15-9. Unique Identifier : AIDSLINE MED/92106862; Tudor-Williams G; St Clair MH; McKinney RE; Maha M; Walter E; Santacroce S; Mintz M; O'Donnell K; Rudoll T; Vavro CL; et al; Department of Pediatrics, Duke University Medical Center, Durham,; North Carolina.; In adults with the acquired immunodeficiency syndrome, long-term monotherapy with zidovudine selects for human immunodeficiency virus type 1 (HIV-1) strains with substantially reduced in-vitro susceptibility to the drug. We have assessed the relation between in-vitro resistance to zidovudine and clinical outcome in ch
Twinning among HIV-infected mothers [letter]: Lancet. 1992 Jan 4;339(8784):66-7. Unique Identifier : AIDSLINE MED/92106910; Lallemant-Le Coeur S; Lallemant M
Social care of children born to HIV-infected parents [letter]: Lancet. 1992 Jan 18;339(8786):189-90. Unique Identifier : AIDSLINE MED/92106968; Giaquinto C; Giacomet V; Pagliaro A; Ruga E; Cozzani S; D'Elia R; Newell ML
Formulations of didanosine (ddI) and salt overload [letter] [see comments]: Lancet. 1992 Jan 18;339(8786):190. Unique Identifier : AIDSLINE MED/92106969; Willocks L; Brettle R; Keen J; Valentine C; Pinching AJ
Selective killing of CD4+ cells harboring a human immunodeficiency virus-inducible suicide gene prevents viral spread in an infected cell population.: Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):182-6. Unique Identifier : AIDSLINE MED/92108015; Caruso M; Klatzmann D; Laboratoire de Biologie et Genetique des Pathologies; Immunitaires, Hopital de la Pitie-Salpetriere, Paris, France.; We have stably expressed in CD4+ lymphoid cells the herpes simplex virus type 1 thymidine kinase (HSV1-TK) gene under the control of the human immunodeficiency virus (HIV) promoter and transactivation response element sequences. Upon HIV infection these regulatory sequences were transactivated, switching on high-level
Human immunodeficiency virus (HIV) type 1 can superinfect HIV-2-infected cells: pseudotype virions produced with expanded cellular host range.: Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):363-7. Unique Identifier : AIDSLINE MED/92108055; Le Guern M; Levy JA; Cancer Research Institute, University of California, School of; Medicine, San Francisco 94143-0128.; In studies on viral interference, cloned T-cell lines chronically infected with human immunodeficiency virus (HIV) type 1 or HIV-2 were inoculated with several strains of these two AIDS retrovirus subtypes. HIV-2UC1-infected cells, which still express the CD4 receptor, could be superinfected with a variety of HIV-1 an
TNF-alpha production by U937 promonocytes is enhanced by factors released from HIV-infected T4 lymphocytes: TNF-alpha is one of the mediators causing lysis of HIV-infected T4 cells.: Clin Immunol Immunopathol. 1992 Feb;62(2):168-75. Unique Identifier : AIDSLINE MED/92110960; Hober D; Lucas B; Wattre P; Capron A; Haque A; Centre d'Immunologie et de Biologie Parasitaire, Institut; Pasteur, Lille, France.; In the present study, we have shown that the addition of culture supernatants from HIV-infected SupT1 cells (T4) but not from noninfected cells markedly increased the production of TNF-alpha by U937 promonocytic cells after stimulation with phorbol 12-myristate 13-acetate (PMA). Pretreatment of supernatants with the a
Elevation of IgE in HIV-infected subjects: a marker of poor prognosis.: J Allergy Clin Immunol. 1992 Jan;89(1 Pt 1):68-75. Unique Identifier : AIDSLINE MED/92113183; Israel-Biet D; Labrousse F; Tourani JM; Sors H; Andrieu JM; Even P; Department of Specialized Medicine and Immunopathology, Hopital; Laennec, Paris, France.; The IgE synthesis is tightly controlled by a complex network of T and B cells. Because human immunodeficiency virus (HIV) disease associates T cell activation and depletion, polyclonal B cell activation, atopic symptoms, drug hypersensitivity, and autoimmune activity, we have evaluated IgE, as well as IgA, IgG, and Ig
CD4+ lymphocyte cell enumeration for prediction of clinical course of human immunodeficiency virus disease: a review [see comments]: J Infect Dis. 1992 Feb;165(2):352-63. Unique Identifier : AIDSLINE MED/92113343; Stein DS; Korvick JA; Vermund SH; Medical Branche, Division of AIDS, National Institutes of Allergy; and Infectious Diseases, National Institutes of Health, Bethesda,; Maryland 20892.; Over the last 10 years the appreciation of the full breadth of the spectrum of human immunodeficiency virus (HIV) infection has gradually increased; it is now known that AIDS represents merely the end stage of this progressive infectious process. The surrogate marker that most closely correlates with the stage of HIV
AIDS in Africa [news]: Lancet. 1992 Jan 25;339(8787):238. Unique Identifier : AIDSLINE MED/92114579; Potts M
Trial by myth [news]: Lancet. 1992 Jan 25;339(8787):239. Unique Identifier : AIDSLINE MED/92114580
Intrauterine and intrapartum transmission of HIV [letter; comment]: Lancet. 1992 Jan 25;339(8787):245-6. Unique Identifier : AIDSLINE MED/92114591; Ehrnst A; Lindgren S; Belfrage E; Sonnerborg A; Dictor M; Johansson B; Bohlin AB
Transmission of HIV-1 infection after a fight [letter]: Lancet. 1992 Jan 25;339(8787):246. Unique Identifier : AIDSLINE MED/92114592; O'Farrell N; Tovey SJ; Morgan-Capner P
Treatment of CMV retinitis [letter; comment] [see comments]: Lancet. 1992 Jan 25;339(8787):247. Unique Identifier : AIDSLINE MED/92114595; Morris DJ
Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.: J Exp Med. 1992 Feb 1;175(2):331-40. Unique Identifier : AIDSLINE MED/92121814; Groux H; Torpier G; Monte D; Mouton Y; Capron A; Ameisen JC; Unite Institut National de la Sante et de la Recherche; Medicale U167-Centre National de la Recherche Scientifique 624,; Instiut Pasteur, Lille, France.; In immature thymocytes, T cell receptor for antigen (TCR) mobilization leads to an active T cell suicide process, apoptosis, which is involved in the selection of the T cell repertoire. We have proposed that inappropriate induction of such a cell death program in the mature CD4+ T cell population could account for bot
The cumulative risk of AIDS as the CD4 lymphocyte count declines.: J Acquir Immune Defic Syndr. 1992;5(2):148-52. Unique Identifier : AIDSLINE MED/92122101; Phillips AN; Lee CA; Elford J; Janossy G; Kernoff PB; Haemophilia Centre, Royal Free Hospital and School of Medicine,; London, England.; A method is proposed for assessing the cumulative risk of various AIDS-defining conditions as the CD4 lymphocyte count declines in HIV-infected individuals. The method is analogous to survival analysis but is based on the CD4 lymphocyte count rather than on time. Thus, the level to which the CD4 lymphocyte count has d
Medical care following HIV testing [letter]: JAMA. 1992 Feb 12;267(6):805-6. Unique Identifier : AIDSLINE MED/92122430; Henry K; Sonnen M
Intrarectal challenge of macaques vaccinated with formalin-inactivated simian immunodeficiency virus.: Lancet. 1992 Feb 1;339(8788):273-4. Unique Identifier : AIDSLINE MED/92122865; Cranage MP; Baskerville A; Ashworth LA; Dennis M; Cook N; Sharpe S; Farrar G; Rose J; Kitchin PA; Greenaway PJ; Division of Pathology, PHLS Centre for Applied Microbiology and; Research, Porton Down, Wiltshire, UK.; Macaques can be protected from intravenous infection with simian immunodeficiency virus (SIV) by vaccination with chemically inactivated virus. However, protection against infection via a mucosal surface has not been demonstrated. We vaccinated four rhesus macaques with formalin-inactivated SIV given intramuscularly.
Vertical transmission of HTLV-I [letter; comment]: Lancet. 1992 Feb 1;339(8788):305-6. Unique Identifier : AIDSLINE MED/92122886; Miyoshi I; Muneishi H; Tanaka Y
Efficacy of cytarabine in progressive multifocal leucoencephalopathy in AIDS [letter; comment]: Lancet. 1992 Feb 1;339(8788):306. Unique Identifier : AIDSLINE MED/92122887; Nicoli F; Chave B; Peragut JC; Gastaut JL
A controlled trial of early versus late treatment with zidovudine in symptomatic human immunodeficiency virus infection. Results of the Veterans Affairs Cooperative Study [see comments]: N Engl J Med. 1992 Feb 13;326(7):437-43. Unique Identifier : AIDSLINE MED/92123281; Hamilton JD; Hartigan PM; Simberkoff MS; Day PL; Diamond GR; Dickinson GM; Drusano GL; Egorin MJ; George WL; Gordin FM; et al; Department of Veterans Affairs Medical Centers, Baltimore.; BACKGROUND. Zidovudine is recommended for asymptomatic and early symptomatic human immunodeficiency virus (HIV) infection. The best time to initiate zidovudine treatment remains uncertain, however, and whether early treatment improves survival has not been established. METHODS. We conducted a multicenter, randomized,
Effect of cacao husk extract on human immunodeficiency virus infection.: Lett Appl Microbiol. 1991 Dec;13(6):251-4. Unique Identifier : AIDSLINE MED/92096226; Unten S; Ushijima H; Shimizu H; Tsuchie H; Kitamura T; Moritome N; Sakagami H; AIDS Research Center, National Institute of Health, Tokyo, Japan.; A sodium hydroxide extract from cacao husk inhibited the cytopathic effect of human immunodeficiency virus type 1 (HIV-1) against HTLV-1-transformed T-cell lines MT-2 and MT-4. It also inhibited syncytium formation between HIV-infected and uninfected lymphoblastoid T-cell line, MOLT-4. The anti-HIV activity was concen
Oligonucleotides: problems and frontiers of practical applications.: Trends Biotechnol. 1991 Oct;9(10):339-40. Unique Identifier : AIDSLINE MED/92102644; Helene C; Le Doan T; Laboratoire de Biophysique, Museum National d'Histoire; Naturelle, INSERM U.201-CNRS UA. 481, Paris, France.
Poliovirus antigen chimeras.: Trends Biotechnol. 1991 Dec;9(12):415-21. Unique Identifier : AIDSLINE MED/92096204; Rose CS; Evans DJ; Department of Microbiology, University of Reading, Whiteknights,; UK.; Poliovirus, the aetiological agent of paralytic poliomyelitis, is arguably the best characterized of all animal viruses. Using recombinant-DNA technology, this information, together with the availability of infectious cDNA clones of the notably safe and efficacious live attenuated Sabin 1 vaccine strains of poliovirus
Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects.: J Infect Dis. 1992 Jan;165(1):105-10. Unique Identifier : AIDSLINE MED/92091856; Boucher CA; O'Sullivan E; Mulder JW; Ramautarsing C; Kellam P; Darby G; Lange JM; Goudsmit J; Larder BA; Department of Virology, University of Amsterdam, Netherlands.; The order of appearance in the reverse transcriptase gene of four mutations implicated in the development of resistance to zidovudine was investigated by selective polymerase chain reaction. Serial human immunodeficiency virus isolates were studied from 18 initially asymptomatic individuals who had been treated with z
Morphometric comparisons of optic nerve axon loss in acquired immunodeficiency syndrome.: Am J Ophthalmol. 1992 Jan 15;113(1):14-20. Unique Identifier : AIDSLINE MED/92095344; Tenhula WN; Xu SZ; Madigan MC; Heller K; Freeman WR; Sadun AA; Department of Ophthalmology and Neurosurgery, University of; Southern California, School of Medicine, Los Angeles.; Axonal degeneration and diminution of the axonal population in the optic nerve have been documented in aging and in various neuro-ophthalmic conditions. We applied morphometric techniques to the postmortem examination of optic nerves obtained from patients with acquired immunodeficiency syndrome. Twelve optic nerves (
BEAM regimen and G-CSF in HTLV-I-associated T-cell lymphoma [letter]: Lancet. 1992 Jan 11;339(8785):133-4. Unique Identifier : AIDSLINE MED/92099757; Brito-Babapulle F; Arya R; Griffiths T; Pagliuca A; Mufti GJ
A dual anti-tumor effect of a combination of interferon-alpha or interleukin-2 and 5-fluorouracil on natural killer (NK) cell-mediated cytotoxicity.: Clin Immunol Immunopathol. 1992 Jan;62(1 Pt 1):103-11. Unique Identifier : AIDSLINE MED/92103799; Reiter Z; Ozes ON; Blatt LM; Taylor MW; Department of Biology, Indiana University, Bloomington 47405.; Previous in vitro and in vivo studies have shown a synergism between interferon (IFN) and 5-fluorouracil (5-FU) against different tumor cell lines. In the present study we report that the combination of IFN-alpha and 5-FU has a significant effect not only on the inhibition of tumor cell growth but also on the regulati
Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1).: J Clin Invest. 1992 Jan;89(1):176-83. Unique Identifier : AIDSLINE MED/92105381; Rich EA; Chen IS; Zack JA; Leonard ML; O'Brien WA; Department of Medicine, Case Western Reserve University,; Cleveland, Ohio.; Differences in susceptibility to infection of most mononuclear phagocytes with HIV-1 are not known. We investigated the relative susceptibility of autologous freshly isolated blood monocytes (MN), MN cultured in vitro to allow differentiation (CM), and alveolar macrophages (AM) from healthy subjects to productive infe
Carboxyl-terminal and central regions of human immunodeficiency virus-1 NEF recognized by cytotoxic T lymphocytes from lymphoid organs. An in vitro limiting dilution analysis.: J Clin Invest. 1992 Jan;89(1):53-60. Unique Identifier : AIDSLINE MED/92105407; Hadida F; Parrot A; Kieny MP; Sadat-Sowti B; Mayaud C; Debre P; Autran B; Laboratoire d'Immunologie Cellulaire et Tissulaire, Centre; Hopitalier Universitaire Pitie-Salpetriere, Paris, France.; Cytotoxic T lymphocytes (CTL) specific for human immunodeficiency virus (HIV) proteins have been analyzed in lymphoid organs from seropositive patients. Indeed, an active HIV replication coexists with a major CD8+ lymphocytic infiltration in these organs. We have shown in a previous report that HIV-seropositive patien
Enhancement of HIV-1 infection by the capsular polysaccharide of Cryptococcus neoformans.: Lancet. 1992 Jan 4;339(8784):21-3. Unique Identifier : AIDSLINE MED/92106864; Pettoello-Mantovani M; Casadevall A; Kollmann TR; Rubinstein A; Goldstein H; Department of Pediatrics, Albert Einstein College of Medicine,; Bronx, New York 10461.; Patients with AIDS who become infected with Cryptococcus neoformans have a poor prognosis. We speculated that the presence of cryptococcal capsular polysaccharide may enhance HIV-1 infection. In an in-vitro study, the presence of cryptococcal polysaccharide significantly increased (p less than 0.05) production of p24
The gene for B7, a costimulatory signal for T-cell activation, maps to chromosomal region 3q13.3-3q21.: Blood. 1992 Jan 15;79(2):489-94. Unique Identifier : AIDSLINE MED/92110585; Freeman GJ; Disteche CM; Gribben JG; Adler DA; Freedman AS; Dougery J; Nadler LM; Division of Tumor Immunology, Dana-Farber Cancer Institute,; Boston, MA 02115.; B7 is an activation antigen expressed on activated B cells and gamma-interferon-stimulated monocytes. The B7 antigen is the natural ligand for CD28 on T cells. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of
Identification of a CD21 receptor-deficient, non-Ig-secreting peripheral B lymphocyte subset in HIV-seropositive drug abusers.: Clin Immunol Immunopathol. 1992 Feb;62(2):139-47. Unique Identifier : AIDSLINE MED/92110957; Benedetto A; Di Caro A; Camporiondo MP; Gallone D; Zaniratti S; Tozzi V; Elia G; Center of Virology USL, Osp. S. Camillo, Rome, Italy.; We have studied 61 HIV-seropositive heroin addicts (18 asymptomatic, 20 ARC, and 23 AIDS cases), 26 HIV-seronegative heroin addicts, and 45 healthy blood donors, matching the groups each other for age and sex. We have focused on the phenotypic characteristics of B subpopulations in the peripheral blood of HIV-seroposi
Age-associated increase in number of CD4+CD8+ intestinal intraepithelial lymphocytes in rats.: Eur J Immunol. 1992 Jan;22(1):159-64. Unique Identifier : AIDSLINE MED/92111620; Takimoto H; Nakamura T; Takeuchi M; Sumi Y; Tanaka T; Nomoto K; Yoshikai Y; Laboratory of Germfree Life, Nagoya, University School of; Medicine, Japan.; A significant number of CD4+CD8+ T cells were detected in intestinal intraepithelial lymphocytes (IEL) of various strains of rats including Wistar, WKA, BN, LEW and F344. The site of the CD4+CD8+ population in IEL increased with age in all strains we examined. Most IEL bearing CD8 expressed no CD5 antigen in young rat
The binding of a novel bisheteroarylpiperazine mediates inhibition of human immunodeficiency virus type 1 reverse transcriptase.: J Biol Chem. 1992 Jan 5;267(1):27-30. Unique Identifier : AIDSLINE MED/92112661; Dueweke TJ; Kezdy FJ; Waszak GA; Deibel MR Jr; Tarpley WG; Upjohn Laboratories, Kalamazoo, Michigan 49001-0199.; The bisheteroarylpiperazines (BHAPs) are potent inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and specifically block HIV-1 replication (Romero, D. L., Busso, M., Tan, C.-K., Reusser, F., Palmer, J. R., Poppe, S. M., Aristoff, P. A., Downey, K. M., So, A. G., Resnick, L., and Tarp
The effects of cysteine mutations on the reverse transcriptases of human immunodeficiency virus types 1 and 2.: J Biol Chem. 1992 Jan 15;267(2):1293-7. Unique Identifier : AIDSLINE MED/92112775; Hizi A; Shaharabany M; Tal R; Hughes SH; Department of Cell Biology and Histology, Sackler School of; Medicine, Tel Aviv University, Israel.; Chemical modification of HIV-1 and HIV-2 (human immunodeficiency virus, types 1 and 2) reverse transcriptases (RT) with three thiol reactive compounds selectively inhibits the RNase H function of the enzyme. HIV-1 RT has 2 cysteines (at positions 38 and 280); HIV-2 RT has 3 (38, 280, 445). Both of the cysteines in HIV
A network antigen for human CD4. A murine monoclonal anti-idiotype to Leu-3a induces an anti-CD4 response in naive mice.: J Immunol. 1992 Feb 1;148(3):821-6. Unique Identifier : AIDSLINE MED/92113265; Healey DG; Dianda L; Beverley PC; Human Tumour Immunology Group, Imperial Cancer Research Fund,; London, UK.; Previous studies have evaluated anti-CD4 mAb as idiotypic models of the HIV gp120-binding site for CD4. The success of this strategy depends upon the concept of internal image, whereby the binding paratope of the anti-CD4 structurally mimics the equivalent binding surface on HIV gp120. To test this concept of internal
A chemically defined synthetic vaccine model for HIV-1.: J Immunol. 1992 Feb 1;148(3):914-20. Unique Identifier : AIDSLINE MED/92113278; Nardelli B; Lu YA; Shiu DR; Delpierre-Defoort C; Profy AT; Tam JP; Rockefeller University, New York, NY 10021.; Multiple Ag peptide (MAP) system without the use of a protein carrier was used as a vaccine model in three species of animals. Synthetic peptides from the V3 region of the gp120 of IIIB, RF and MN HIV-1 isolates were used as the Ag. MAP consisting of various chain lengths, from 11 to 24 residues, were prepared in a mo
Geographic diversity of human immunodeficiency virus type 1: serologic reactivity to env epitopes and relationship to neutralization.: J Infect Dis. 1992 Feb;165(2):256-61. Unique Identifier : AIDSLINE MED/92113330; Cheingsong-Popov R; Callow D; Beddows S; Shaunak S; Wasi C; Kaleebu P; Gilks C; Petrascu IV; Garaev MM; Watts DM; et al; St. Mary's Hospital Medical School, London, United Kingdom.; The antibody recognition of the major neutralization epitopes of human immunodeficiency virus type 1 (HIV-1) in 829 HIV-1-seropositive subjects from North America (106), Europe (241), Africa (342), and Asia (100) was investigated. Peptides derived from diverse published V3 loop sequences were used as antigen, and seru
Segregation of human T cell lymphotropic virus type I and II infections by antibody reactivity to unique viral epitopes.: J Infect Dis. 1992 Feb;165(2):268-72. Unique Identifier : AIDSLINE MED/92113332; Lipka JJ; Miyoshi I; Hadlock KG; Reyes GR; Chow TP; Blattner WA; Shaw GM; Hanson CV; Gallo D; Chan L; et al; Department of Pathology, Stanford University School of Medicine,; CA.; A recombinant protein of the human T cell lymphotropic virus type I (HTLV-I) gp46 outer membrane envelope, MTA-4 (residues 129-203), reacted by Western blot with sera from HTLV-I-infected individuals from the United States and Jamaica but not with
Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1.: J Virol. 1992 Feb;66(2):1031-9. Unique Identifier : AIDSLINE MED/92114124; Boyer PL; Ferris AL; Hughes SH; ABL-Basic Research Program, NCI-Frederick Cancer Research and; Development Center, Maryland 21702-1201.; We constructed a series of BspMI cassettes that simplify the introduction of specific point mutations in the polymerase domain of human immunodeficiency virus type 1 reverse transcriptase. A series of point mutants were constructed by using these cassette vectors. The RNA-dependent DNA polymerase and RNase H activitie
RNase H activity associated with reverse transcriptase from feline immunodeficiency virus.: J Virol. 1992 Feb;66(2):1215-8. Unique Identifier : AIDSLINE MED/92114148; Cronn RC; Whitmer JD; North TW; Division of Biological Sciences, University of Montana, Missoula; 59812-1002.; Reverse transcription of retroviral genomes requires the action of an RNase H for template switching and primer generation. In this report, we compare enzymatic properties of the RNase H associated with the reverse transcriptase (RT) from feline immunodeficiency virus (FIV) and that from human immunodeficiency virus (
Defects in Moloney murine leukemia virus replication caused by a reverse transcriptase mutation modeled on the structure of Escherichia coli RNase H.: J Virol. 1992 Feb;66(2):615-22. Unique Identifier : AIDSLINE MED/92114162; Telesnitsky A; Blain SW; Goff SP; Department of Biochemistry and Molecular Biophysics, Columbia; University College of Physicians and Surgeons, New York, New York; 10032.; We have studied a mutant Moloney murine leukemia virus with a deletion in reverse transcriptase (RT) which is predicted to make its RNase H domain resemble structurally that of human immunodeficiency virus RT. This deletion was based on improved RNase H homology alignments made possible by the recently solved three-di
Detailed mapping of the antigenicity of the surface unit glycoprotein of equine infectious anemia virus by using synthetic peptide strategies.: J Virol. 1992 Feb;66(2):732-42. Unique Identifier : AIDSLINE MED/92114175; Ball JM; Rushlow KE; Issel CJ; Montelaro RC; Department of Molecular Genetics and Biochemistry, University of; Pittsburgh School of Medicine, Pennsylvania 15261.; We describe here a detailed analysis of the antigenic determinants of the surface unit glycoprotein (gp90) of equine infectious anemia virus (EIAV), using a comprehensive panel of synthetic peptides in enzyme-linked immunosorbent assays with immune serum from naturally and experimentally infected horses and with a pan
Three epitopic peptides of the simian immunodeficiency virus Nef protein recognized by macaque cytolytic T lymphocytes.: J Virol. 1992 Feb;66(2):750-6. Unique Identifier : AIDSLINE MED/92114177; Bourgault I; Venet A; Levy JP; Institut Cochin de Genetique Moleculaire, Hopital Cochin,; Paris, France.; In 8 of 12 experimentally infected macaques, the Nef SIVmac 251 protein was recognized by cytolytic T lymphocytes (CTL) and appeared strongly immunogenic. Here, we report experiments which have been performed by using synthetic peptides to precisely determine the epitopes recognized by macaque CTL. Three epitopes of t
Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120.: J Virol. 1992 Feb;66(2):848-56. Unique Identifier : AIDSLINE MED/92114188; Fung MS; Sun CR; Gordon WL; Liou RS; Chang TW; Sun WN; Daar ES; Ho DD; Tanox Biosystems, Inc., Houston, Texas 77025.; Two monoclonal antibodies designated BAT085 and G3-136 were raised by immunizing BALB/c mice with gp120 purified from human immunodeficiency virus type 1 (HIV-1) IIIB-infected H9 cell extracts. Among three HIV-1 laboratory isolates (IIIB, MN, and RF), BAT085 neutralized only IIIB infection of CEM-SS cells, whereas G3-
Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins.: Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):461-5. Unique Identifier : AIDSLINE MED/92115682; Broliden PA; von Gegerfelt A; Clapham P; Rosen J; Fenyo EM; Wahren B; Broliden K; Department of Virology, National Bacteriological Laboratory,; Stockholm, Sweden.; Four major neutralizing regions of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein were identified and characterized with a panel of 80 HIV-1 antibody-positive human sera. Levels of neutralizing antibodies against the HIV-1 strains IIIB, SF2, and RF were compared with reactivity in ELISAs against
Inhibitory effect of HIV-1 envelope glycoproteins gp120 and gp160 on the in vitro growth of enriched (CD34+) hematopoietic progenitor cells.: Arch Virol. 1992;122(3-4):271-80. Unique Identifier : AIDSLINE MED/92117865; Zauli G; Re MC; Visani G; Furlini G; La Placa M; Institute of Microbiology, University of Bologna, Italy.; The effect of increasing concentrations (from 0.01 to 10 micrograms/ml) of HIV-1 envelope glycoproteins gp160, gp120, gp41 and core protein p24 was evaluated on the in vitro growth of enriched hematopoietic progenitors (CD34+ cells). Both gp120 and gp160, at concentrations from 0.01 to 10 micrograms/ml, caused a progr
Identification of the primer binding domain in human immunodeficiency virus reverse transcriptase.: Biochemistry. 1992 Jan 21;31(2):616-23. Unique Identifier : AIDSLINE MED/92118864; Basu A; Ahluwalia KK; Basu S; Modak MJ; Department of Biochemistry and Molecular Biology, University of; Medicine and Dentistry of New Jersey, Newark 07103-2714.; We have labeled the primer binding domain of HIV1-RT with 5 -32P-labeled (dT)15 primer using ultraviolet light energy. The specificity of the primer cross-linking to HIV1-RT was demonstrated by competition experiments. Both synthetic and natural primers, e.g., p(dA)15, p(dC)15, and tRNA(Lys), inhibit p(dT)15 binding a
Cerebrospinal fluid myelin basic protein as predictive marker of demyelination in AIDS dementia complex.: J Neuroimmunol. 1992 Feb;36(2-3):251-4. Unique Identifier : AIDSLINE MED/92121424; Liuzzi GM; Mastroianni CM; Vullo V; Jirillo E; Delia S; Riccio P; Dipartimento di Biochimica e Biologia Molecolare, Universita di; Bari, Italy.; Myelin basic protein (MBP) was measured in cerebrospinal fluid (CSF) of patients with acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) in order to investigate the degree of white matter destruction. Results show that increased CSF levels of MBP were detected in all
Genetic modulation of antigen presentation by HLA-B27 molecules.: J Exp Med. 1992 Feb 1;175(2):361-9. Unique Identifier : AIDSLINE MED/92121817; Pazmany L; Rowland-Jones S; Huet S; Hill A; Sutton J; Murray R; Brooks J; McMichael A; Institute of Molecular Medicine, John Radcliffe Hospital,; Headington, Oxford, United Kingdom.; In studies of antigenic peptide presentation, we have found a healthy volunteer whose lymphoblastoid cells were unable to present three different virus-derived epitopes to cytotoxic T lymphocytes (CTL) despite expressing the correct restricting HLA-B27 molecules on the cell surface. B cell lines were established from
Identification of B-cell antigenic sites on HIV-2 gp125.: J Acquir Immune Defic Syndr. 1992;5(2):177-87. Unique Identifier : AIDSLINE MED/92122106; Mannervik M; Putkonen P; Ruden U; Kent KA; Norrby E; Wahren B; Broliden PA; Department of Virology, National Bacteriological Laboratory,; Stockholm, Sweden.; Synthetic peptides were used to identify continuous antigenic sites on the external envelope glycoprotein gp125 of human immunodeficiency virus (HIV)-2. Initially, seven HIV-2-positive human serum samples were screened with 172 sequential nonapeptides containing a six-amino-acid overlap. This represents the entire gp1
Crystal structure of nevirapine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase, and computational alignment with a structurally diverse inhibitor.: J Med Chem. 1992 Jan;35(1):201-2. Unique Identifier : AIDSLINE MED/92122221; Mui PW; Jacober SP; Hargrave KD; Adams J; Department of Medicinal Chemistry, Boehringer Ingelheim; Pharmaceuticals, Inc., Ridgefield, Connecticut 06877.
Allosteric inhibition of human immunodeficiency virus type 1 reverse transcriptase by tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and thione compounds.: Mol Pharmacol. 1992 Jan;41(1):203-8. Unique Identifier : AIDSLINE MED/92123146; Debyser Z; Pauwels R; Andries K; Desmyter J; Engelborghs Y; Janssen PA; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; The reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) is present in virions and infected cells as an heterodimer (p66/p51). A new class of potent and selective HIV-1 inhibitors, the tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and thione (TIBO) derivatives, were found to exert their
Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles.: Virology. 1992 Feb;186(2):712-24. Unique Identifier : AIDSLINE MED/92124746; Sato H; Orenstein J; Dimitrov D; Martin M; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, Maryland 20892.; Although virus infections have been classically studied with cell-free virio