Epidermal interleukin 1 in normal skin of patients with HIV infection. NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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Epidermal interleukin 1 in normal skin of patients with HIV infection.

Br J Dermatol. 1990 Oct;123(4):487-92. Unique Identifier : AIDSLINE MED/91248703
Dreno B; Milpied B; Dutartre H; Litoux P; Department of Dermatology, Hotel Dieu, Nantes, France.

Abstract: Interleukin 1 (IL-1) in the epidermis plays an important role together with Langerhans cells in the activation of the T cells. To determine whether IL-1 could be located in the normal epidermis of 54 patients with HIV infection and related to the stage of the disease, an indirect immunofluorescence technique was used. Intense epidermal fluorescence to IL-1 was noted in the asymptomatic stage II of the disease, whereas there was minimal reactivity in the other stages.
Keywords: Acquired Immunodeficiency Syndrome/*METABOLISM/PATHOLOGY Adolescence Adult Female Human *HIV-1 Immunohistochemistry Interleukin-1/*METABOLISM Male Middle Age Skin/*METABOLISM JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDmetabolism/pathologyadolescenceadultfemalehumanKWDhiv-1immunohistochemistryinterleukin-1/KWDmetabolismmalemiddleageskin/KWDmetabolismjournalarticle
910930
M9190683

Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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