[Infectious esophagitis in HIV infection] NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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[Infectious esophagitis in HIV infection]

Rev Med Interne. 1990 May-Jun;11(3):223-8. Unique Identifier : AIDSLINE MED/91262255
Pauwels A; Lecomte I; Eliaszewicz MC; Meyohas MC; Service d'Hepato-Gastroenterologie, Hopital Tenon, Paris.

Abstract: Infectious oesophagitis is the most frequent of digestive tract diseases occurring in patients with AIDS. It is diagnosed by endoscopy which permits brushing and biopsy of mucosal lesions for cytological, histological and microbiological examinations. In 40 to 50 percent of HIV positive patients, Candida is responsible for oesophagitis which is often asymptomatic and almost regularly associated with oral candidiasis. Brushing is preferable to biopsy to confirm a diagnosis which is frequently obvious at endoscopy. The prevalence of CMV and HSV oesophagitis has perhaps been underestimated. Diagnosis rests on the finding of intranuclear inclusions, usually in endothelial cells of the chorion for CMV and in epithelial cells for HSV. The demonstration of viral antigens by immunoperoxidase staining is useful in difficult cases, as is viral culture. Antiviral agents (gancyclovir against CMV, acyclovir against HSV) are usually effective. Co-infection with both Candida and a virus is not uncommon. The other pathogens, such as bacteria or mycobacteria, are exceptional. The authors suggest a therapeutic strategy taking into account epidemiological and clinical data.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Bacterial Infections/ETIOLOGY Candidiasis/ETIOLOGY English Abstract Esophagitis/*ETIOLOGY Human Opportunistic Infections/*ETIOLOGY Virus Diseases/ETIOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIALKWDacquiredimmunodeficiencysyndrome/KWDcomplicationsbacterialinfections/etiologycandidiasis/etiologyenglishabstractesophagitis/KWDetiologyhumanopportunisticinfections/KWDetiologyvirusdiseases/etiologyjournalarticlereviewreview,tutorial
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Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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