Comparison of cotton wool swab and cytobrush for detection of chlamydial infection in women attending a genitourinary medicine clinic. NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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Comparison of cotton wool swab and cytobrush for detection of chlamydial infection in women attending a genitourinary medicine clinic.

Int J STD AIDS. 1991 Jan-Feb;2(1):49-51. Unique Identifier : AIDSLINE MED/91242690
Mandal D; Ray TK; Richmond SJ; Goorney BP; Haye KR; Department of Genitourinary Medicine, Manchester Royal Infirmary,; UK.

Abstract: Endocervical specimens obtained by cytobrush and conventional cotton wool swabs from 90 women attending a genitourinary medicine clinic were compared for their efficiency in detecting chlamydial infection. Isolation of Chlamydia trachomatis and detection of the chlamydial lipopolysaccharide antigen were attempted on each specimen. Antigen was detected in 18% of cytobrush and 17% of swab specimens. The cytobrush proved less suitable than swabs for isolation because 8 cytobrush specimens (9%) were toxic to the McCoy cells. Toxicity was significantly associated with an infected endocervix (2P = 0.004). Cytobrush therefore appeared to have little advantage over the much cheaper alternative, the cotton wool swab.
Keywords: Antigens, Bacterial/ANALYSIS *Chlamydia trachomatis Chlamydia Infections/DIAGNOSIS/EPIDEMIOLOGY/*PATHOLOGY Comparative Study England/EPIDEMIOLOGY False Negative Reactions Female Genital Diseases, Female/DIAGNOSIS/EPIDEMIOLOGY/*PATHOLOGY Human Outpatient Clinics, Hospital Sensitivity and Specificity Vaginal Smears/*INSTRUMENTATION/METHODS CLINICAL TRIAL JOURNAL ARTICLEKWDantigens,bacterial/analysisKWDchlamydiatrachomatischlamydiainfections/diagnosis/epidemiology/KWDpathologycomparativestudyengland/epidemiologyfalsenegativereactionsfemalegenitaldiseases,female/diagnosis/epidemiology/KWDpathologyhumanoutpatientclinics,hospitalsensitivityandspecificityvaginalsmears/KWDinstrumentation/methodsclinicaltrialjournalarticle
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M9190603

Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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