Immunologic abnormalities in patients with chronic delta infection. NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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Immunologic abnormalities in patients with chronic delta infection.

Boll Ist Sieroter Milan. 1988;67(5-6):337-44. Unique Identifier : AIDSLINE MED/91299259
Castello G; Ciampi R; Leonardi E; Abrescia N; Ronga D; D'Alessio V; Sezione di Ematologia ed Immunologia Clinica, Istituto Nazionale; per lo Studio e la Cura dei Tumori, Napoli.

Abstract: Data reported in this paper emphasize the existence of close relationships between hepatitis delta patients and subjects affected by other viral diseases, first of all AIDS and related conditions. Some immunologic abnormalities characterizing initial stages of HIV infection (reduced CD4/CD8 ratio, based on increased CD8+ cells; B-cell polyclonal activation with the presence of circulating immune complexes) were found, in fact, also in delta patients. No statistically significant difference was observed by comparing delta vs no delta subjects.
Keywords: Adolescence Adult Antigen-Antibody Complex/*BLOOD Child Comparative Study *CD4-Positive T-Lymphocytes Delta Infection/COMPLICATIONS/*IMMUNOLOGY Female Hepatitis B/COMPLICATIONS/IMMUNOLOGY Hepatitis, Chronic Active/COMPLICATIONS/*IMMUNOLOGY Human Hypergammaglobulinemia/*ETIOLOGY/IMMUNOLOGY HIV Infections/IMMUNOLOGY IgG/ANALYSIS Immunoglobulins, Light-Chain/ANALYSIS Immunologic Deficiency Syndromes/*ETIOLOGY/IMMUNOLOGY Leukocyte Count Liver Cirrhosis/COMPLICATIONS Male Middle Age *T-Lymphocytes, Suppressor-Effector Virus Diseases/IMMUNOLOGY JOURNAL ARTICLEKWDadolescenceadultantigen-antibodycomplex/KWDbloodchildcomparativestudyKWDcd4-positivet-lymphocytesdeltainfection/complications/KWDimmunologyfemalehepatitisb/complications/immunologyhepatitis,chronicactive/complications/KWDimmunologyhumanhypergammaglobulinemia/KWDetiology/immunologyhivinfections/immunologyigg/analysisimmunoglobulins,light-chain/analysisimmunologicdeficiencysyndromes/KWDetiology/immunologyleukocytecountlivercirrhosis/complicationsmalemiddleageKWDt-lymphocytes,suppressor-effectorvirusdiseases/immunologyjournalarticle
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Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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