Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.
[Prevalence and prognostic significance of anti-HTLV-I and anti-HIV-2 antibodies in patients with HIV infection in the Roman region]
Boll Ist Sieroter Milan. 1988;67(5-6):345-50. Unique Identifier : AIDSLINE MED/91299260 Antinori A; Tamburrini E; Ventura G; Nervo P; Ortona L; Universita Cattolica del Sacro Cuore, Facolta di Medicina e; Chirurgia, Instituto di Clinica delle Malattie Infettive, Roma.
Abstract:
A chronic coinfection with CMV, EBV etc. has been described in patients with HIV infection; recently a coinfection with other retroviruses has been described too. We have looked for the presence of antibodies to HTLV-I (anti HTLV-I) and to HIV-2 (anti HIV-2) in 135 HIV infected (HIV-positive) subjects living in Rome. They were 100 i.v. drug addicts, 24 homo/bisexuals, 4 partners of HIV-positive patients, 5 polytransfused and 2 without any known risk factor; 32 of them had a full-blown AIDS, 52 had ARC and 51 were symptom-free. Anti HIV, anti HTLV-I and anti HIV-2 were detected with ELISA method and confirmed by Western Blot (W.B.) technique. Antibodies to HTLV-I were found in 14 cases (10.4%) and antibodies to HIV-2 in 12 cases (8.9%). The contemporary presence of anti HIV, anti HTLV-I and anti HIV-2 was not found in any subjects. Our data fail to show a clear relationship among the coinfection with different retroviruses and the various risk factors for HIV infection and the HIV-related clinical picture (AIDS, ARC, etc.).
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY Adolescence Adult Aged AIDS-Related Complex/IMMUNOLOGY Comparative Study Cross-Sectional Studies English Abstract Female Human HIV Antibodies/*BLOOD HIV Infections/*COMPLICATIONS/EPIDEMIOLOGY/IMMUNOLOGY HIV-1/IMMUNOLOGY HIV-2/*IMMUNOLOGY HTLV-BLV Antibodies/*BLOOD HTLV-BLV Infections/*COMPLICATIONS/EPIDEMIOLOGY/IMMUNOLOGY HTLV-I/*IMMUNOLOGY Male Middle Age Prognosis Risk Factors Rome/EPIDEMIOLOGY JOURNAL ARTICLE 911030
M91A1110
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