Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.
[Evaluation of the antibody response and antigenemia in anti-HIV positive subjects with or without candidiasis]
G Batteriol Virol Immunol. 1989 Jan-Dec;82(1-12):101-7. Unique Identifier : AIDSLINE MED/91285286 Castelli L; Capra E; Gaido E; Milano R; Sampo A; Laboratorio Analisi Ospedale Amedeo di Savoia, Torino.
Abstract:
As a diagnostic tool in infectious diseases by CANDIDA species, two different commercial kits have been tested. A LATEX agglutination-test for CANDIDA circulating antigens and an E.L.I.S.A. for detecting specific antibodies. We have examined 107 sets of anti-HIV + subjects (63 with positive culture and 44 negative) against 44 health controls. All controls were negative for circulating antigens, where as 27% resulted positive for specific antibodies. In the group of anti-HIV +, with positive culture for CANDIDA the 45% proved positive for CANDIDA circulating antigens, whereas only the 9.5% resulted negative. The results, shown in the present work, suggests the weight of LATEX test for its diagnostic reliability, its simplicity, while the E.L.I.S.A. for detection of specific antibodies turns out of difficult interpretation in distinguishing between common colonization and infection by CANDIDA species.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/IMMUNOLOGY Antibodies, Fungal/*BLOOD Antigens, Fungal/*BLOOD AIDS-Related Complex/COMPLICATIONS/IMMUNOLOGY Candida albicans/*IMMUNOLOGY Candidiasis/ETIOLOGY/*IMMUNOLOGY Comparative Study English Abstract Enzyme-Linked Immunosorbent Assay Esophagitis/IMMUNOLOGY Evaluation Studies Human HIV Seropositivity/COMPLICATIONS/*IMMUNOLOGY Latex Fixation Tests Predictive Value of Tests Reagent Kits, Diagnostic Septicemia/IMMUNOLOGY JOURNAL ARTICLE 911030
M91A1109
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