Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.
[New methods of interlaboratory monitoring of HIV-1 ELISA kits. Comparative study of 2 periods: 1/12/1988 to 15/4/1989 and 15/4/1989 to 31/8/1989. Le Groupe Retrovirus de la Societe Nationale de Transfusion Sanguine]
Rev Fr Transfus Hemobiol. 1990 Jun;33(3):211-22. Unique Identifier : AIDSLINE MED/91000043 North ML; Noel L; Courouce AM
Abstract:
Since december 1st 1988, the Retrovirus study Group of the French Society of Blood Transfusion has initiated a systematic multicentric control of all anti-HIV screening EIA test kits lots used by each member of the group. For this purpose a special panel (GRV) has been designed and forwarded to each laboratory. From december 1st 1988 to august 8 1989, 6 HIV-1 kits have been in use (Diagnostics Pasteur Elavia 1; Diagnostics Pasteur Rapid'Elavia; Organon Vironostika; Abbott HIV recombinant; Du Pont env 9; Wellcome Wellcozyme). The GRV panel has been run 204 times on 102 different lots in 12 laboratories. Results after 9 months show that these 6 kits almost always properly recognize the 5 HIV 1 positive samples of the panel. However they differ in their ability to recognize HIV 2 positive samples. Variations in results are observed from lot to lot as well as between the first half of this period and the second.
Keywords: AIDS Serodiagnosis/*METHODS/STANDARDS Comparative Study English Abstract *Enzyme-Linked Immunosorbent Assay France Human HIV Antibodies/*ANALYSIS HIV Antigens/IMMUNOLOGY HIV Seropositivity/*DIAGNOSIS HIV-1/*IMMUNOLOGY HIV-2/*IMMUNOLOGY Predictive Value of Tests *Reagent Kits, Diagnostic Recombinant Proteins/IMMUNOLOGY JOURNAL ARTICLE 910130
M9110585
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