Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.
HIV AND AIDS: PATHOGENESIS, THERAPY AND VACCINE
J Cell Biochem; (Suppl 14D):77-181 1990. Unique Identifier : AIDSLINE ICDB/90665936 Anonymous; No affiliation given
Abstract:
A symposium on HIV and AIDS, part of the UCLA series, was held in Keystone, Colorado, from March 31 to April 6, 1990. The symposium covered HIV regulation and pathogenesis; cellular targets for HIV infection; genetic and biologic variants of HIV; pathogenic mechanisms and immune responses in HIV; molecular targets for therapy; primate/animal models of AIDS; candidate vaccines and clinical trials; Kaposi's sarcoma and other AIDS-associated malignancies; human T lymphotropic virus-I and other virus cofactors; HIV genes and gene products; cellular and viral (non-HIV) factors that influence HIV production; HIV-related viruses and animal models; serology, immunology, and cell biology; and AIDS vaccine and treatment. Specific topics include replication and pathogenesis of HIV-1, structural organization and regulation of expression of HIV-1, HIV regulatory genes, envelope glycoproteins of HIV-1, epidemiology and natural history of HIV-2, immunopathogenesis of HIV infection, HIV in hematopoiesis, immune reactivity of HIV (damaging or beneficial to the host?), gene therapy for AIDS, interaction of the HIV envelope with the human CD4 receptor, regulation of gene expression in animal and primate lentiviruses, immunobiology of the HIV envelope, biosynthesis and assembly of recombinant HIV proteins, the effects of dideoxynucleosides on HIV infection, molecular interaction of HIV and human cytomegalovirus, limited DNA diversity in HIV-1 isolates obtained from close contacts, detection of HIV-1 proviral sequences in liver cells, retrovirus-mediated transfer of tat and rev genes of HIV, nonessential genes of HIV-1, processing of the gag precursor of HIV, toxin gene regulation by HIV-1 tat and rev, polymerase chain reaction standardization program, expression of HIV-1 protein and mRNA in lymphoid tissue after HIV infection, electron microscopic visualization of HIV reverse transcriptase, effect of recombinant lymphokines on naturally HIV-1-infected CD4+ T cells in vitro, cellular proteins that react with the negative regulatory element of the HIV-1 long-terminal repeat, modulation of HIV-1 multiplication by recombinant interferon-alpha 2 and azidothymidine treatment of monocytic cells, cytokine gene expression during HIV-1 infection of monocytic cells, and possible association between HIV infection in monocytes and the monocyte cell surface antigens CD13 and CD14.
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY/*THERAPY Animal Human HIV/*IMMUNOLOGY HIV Antibodies/ANALYSIS HIV Infections/IMMUNOLOGY/*THERAPY Viral Vaccines/*ADMINISTRATION & DOSAGE MONOGRAPH 910228
M9120718
AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.
Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.
