[The medical interview motivated by the discovery of markers of viral hepatitis permits the identification, in blood donors, of behavior at risk for HIV infection]

Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

[The medical interview motivated by the discovery of markers of viral hepatitis permits the identification, in blood donors, of behavior at risk for HIV infection]

Rev Fr Transfus Hemobiol. 1990 Jul;33(4):249-58. Unique Identifier : AIDSLINE MED/91025299
Guillard A; Tirtaine C; Ouzan D; Follana R; Centre de Transfusion Sanguine des Alpes-Maritimes,; Saint-Laurent-du-Var.

Abstract: From December 1988 to September 1989, 973 blood donors, deferred for anti-HBc reactivity, Ag-HBs positivity, elevated ALT, isolated or associated, but negative for anti-HIV, were interviewed in our blood center in the weeks after donation. Among these 973 donors, 53 (5.4%, 46 males, 7 females) were found at risk for HIV infection: intravenous drug abuse: 24 cases; heterosexuality with multiple partners: 17 cases; homosexuality: 8 cases; sexual relations with persons at risk: 4 cases. These 53 donors did not recognize their risk behaviour during the medical talk before donation. 25 out of these 53 donors were seen afterwards and one of them, homosexual man, seroconverted for anti-HIV seven months after the anti HIV negative but anti-HBc positive blood donation. We conclude that, in our experience, director surrogate viral hepatitis markers help to identify donors at risk for HIV infection, and, in one case, earlier in the course of demonstrated HIV infection than the enzyme immunoassays currently licensed.

Keywords: Alanine Aminotransferase/BLOOD *Blood Donors English Abstract Female Follow-Up Studies Hepatitis B/DIAGNOSIS/IMMUNOLOGY Hepatitis B Antibodies/*ANALYSIS Hepatitis B Core Antigens/ANALYSIS Hepatitis B Surface Antigens/ANALYSIS Human HIV Infections/DIAGNOSIS Male Risk Factors JOURNAL ARTICLE
910228
M9120694

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