IgG subclass deficiency.

Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

IgG subclass deficiency.

Immunodefic Rev. 1990;2(2):129-49. Unique Identifier : AIDSLINE MED/91026001
Preud'homme JL; Hanson LA; Laboratory of Immunology and Immunopathology (CNRS URA 1172),; University Hospital, Poitiers, France.

Abstract: Although the occurrence of selective deficiencies of serum IgG subclasses has been known for 20 years, the large body of data presently available was collected only recently owing to the use of performing monoclonal antibodies. IgG subclass deficiency is frequent, both as an apparently isolated defect (about one fourth of patients suffering otherwise unexplained repeated infections) and in association with a number of primary and required immunodeficiency states. This paper briefly reviews the methodological problems of serum IgG subclass measurement and data on subclass deficiency in a variety of clinical conditions.

Keywords: Acquired Immunodeficiency Syndrome/MICROBIOLOGY Ataxia Telangiectasia/IMMUNOLOGY Bone Marrow Transplantation/IMMUNOLOGY Dysgammaglobulinemia/*DIAGNOSIS Human IgG/*DEFICIENCY Immunoglobulin Isotypes/*DEFICIENCY Immunologic Deficiency Syndromes/*IMMUNOLOGY Wiskott-Aldrich Syndrome/IMMUNOLOGY JOURNAL ARTICLE REVIEW REVIEW, ACADEMIC
910228
M9120692

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