[Pathogenesis and clinical aspects of AIDS] NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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[Pathogenesis and clinical aspects of AIDS]

G Ital Med Lav. 1989 Jan-Mar;11(1-2):15-8. Unique Identifier : AIDSLINE MED/91235882
Maserati R; Minoli L; Istituto di Clinica delle Malattie Infettive, IRCCS Policlinico; San Matteo, Universita di Pavia.

Abstract: Infection by Human Immunodeficiency Virus (HIV) is the recognized cause of the Acquired Immunodeficiency Syndrome (AIDS) and related syndromes, all characterized by a devastating and progressive impairment of immunity. What ensues is the onset of opportunistic infections, neoplasms, both central and peripheral nervous system alterations and other conditions as well. Current therapeutic options, either with antiretroviral and anti-infective drugs, are only credited to prolong survival while not assuring definite cure. A significant improvement in the clinical management of these patients could be anticipated only after a better understanding of HIV life-cycle and its pathogenetic mechanisms.
Keywords: Acquired Immunodeficiency Syndrome/DIAGNOSIS/DRUG THERAPY/ *ETIOLOGY Anti-Infective Agents/THERAPEUTIC USE English Abstract Human HIV/PHYSIOLOGY Prognosis Virus Replication Zidovudine/THERAPEUTIC USE JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/diagnosis/drugtherapy/KWDetiologyanti-infectiveagents/therapeuticuseenglishabstracthumanhiv/physiologyprognosisvirusreplicationzidovudine/therapeuticusejournalarticle
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M9180978

Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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