Chronic fatigue syndrome in northern Nevada. NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Chronic fatigue syndrome in northern Nevada.

Rev Infect Dis. 1991 Jan-Feb;13 Suppl 1:S39-44. Unique Identifier : AIDSLINE MED/91212807
Daugherty SA; Henry BE; Peterson DL; Swarts RL; Bastien S; Thomas RS; Department of Family Medicine, University of Nevada School of; Medicine, Reno 89557.

Abstract: The clinical and laboratory findings from studies of patients with chronic fatigue syndrome (CFS) from northern Nevada are summarized. Physicians caring for these patients have estimated that greater than 400 patients with CFS from northern Nevada and nearby communities in California were identified between 1984 and 1988. As a result of these studies, a cluster of clinical and laboratory features associated with the illness in moderately to severely affected patients has been identified: profound fatigue of prolonged duration; cervical lymphadenopathy; recurrent sore throat and/or symptoms of influenza; loss of cognitive function manifested by loss of memory and loss of ability to concentrate; myalgia; impairment of fine motor skills; abnormal findings on magnetic resonance imaging brain scan; depressed level of antibody to Epstein-Barr virus (EBV) nuclear antigen; elevated level of antibody to EBV early antigen restricted component; elevated ratio of CD4 helper to CD8 suppressor cells; and strong evidence of association of this syndrome with infection with human herpesvirus 6. More-serious and longer-lasting neurologic impairments, including seizures, psychosis, and dementia, have also been observed in some of these patients.
Keywords: Adult Brain/PHYSIOPATHOLOGY Case-Control Studies *Disease Outbreaks Fatigue Syndrome, Chronic/*EPIDEMIOLOGY/MICROBIOLOGY/ PHYSIOPATHOLOGY Female Follow-Up Studies Herpesviridae Infections/MICROBIOLOGY Herpesvirus 6, Human/ISOLATION & PURIF Human Magnetic Resonance Imaging Male Middle Age Nevada/EPIDEMIOLOGY JOURNAL ARTICLE

KWDadultbrain/physiopathologycase-controlstudiesKWDdiseaseoutbreaksfatiguesyndrome,chronic/KWDepidemiology/microbiology/physiopathologyfemalefollow-upstudiesherpesviridaeinfections/microbiologyherpesvirus6,human/isolation&purifhumanmagneticresonanceimagingmalemiddleagenevada/epidemiologyjournalarticle
910830
M9180154

Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1991. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1991. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .