[Cardiac lesions in acquired immunodeficiency syndrome (AIDS). Apropos of an autopsy series of 25 cases] NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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[Cardiac lesions in acquired immunodeficiency syndrome (AIDS). Apropos of an autopsy series of 25 cases]

Ann Pathol. 1990;10(4):247-57. Unique Identifier : AIDSLINE MED/91076949
Hofman P; Michiels JF; Saint Paul MC; Bernard E; Dellamonica P; Loubiere R; Laboratoire d'Anatomie Pathologique, Hopital Pasteur, Nice.

Abstract: The pathologic study of the cardiac lesions in 25 persons who died of AIDS were studied from autopsies. Most of these patients were intravenous drug abusers (14 cases). Heart failure was symptomatic and lead to death in 4 cases. This study showed histological abnormalities in 76% of the cases. We observed 12 myocarditis. In 6 cases, pathogenes were found: Toxoplasma gondii (2), Cryptococcus neoformans (2), Candida (1), Aspergillus (1). A lymphocytic myocarditis was observed in 6 hearts. By immunohistochemical technique, we could distinguish 2 toxoplasmic myocarditis, and in 4 cases, solitary cysts in the myocardium without inflammation. The remaining lesions comprised respectively: 3 lymphocytic pericarditis, 2 marastic endocarditis and 1 dilated myocardiopathy.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Autopsy English Abstract Female Human Male Middle Age Myocardial Diseases/MICROBIOLOGY/*PATHOLOGY Myocarditis/PATHOLOGY JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASESKWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultautopsyenglishabstractfemalehumanmalemiddleagemyocardialdiseases/microbiology/KWDpathologymyocarditis/pathologyjournalarticlereviewreviewofreportedcases
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M9140665

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