Early HIV-related neuropsychological impairment: relationship to stage of viral infection. NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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Early HIV-related neuropsychological impairment: relationship to stage of viral infection.

J Clin Exp Neuropsychol. 1990 Oct;12(5):766-80. Unique Identifier : AIDSLINE MED/91079235
Gibbs A; Andrewes DG; Szmukler G; Mulhall B; Bowden SC; Department of Psychiatry, University of Melbourne, Parkville,; Victoria, Australia.

Abstract: Sixty male outpatients with no past neuropsychiatric history were examined for evidence of early HIV-related neuropsychological impairment. Significant cognitive deficit, as measured by the RAVLT and WAIS-R Digit Symbol Substitution tests, and moderate correlation with indices of immune function, were observed in a group of patients with AIDS-Related Complex [ARC]. Patients with asymptomatic HIV-infection demonstrated no significant differences in performance compared to a group of HIV-seronegative controls. No significant group differences in age, education, predicted-IQ or self-rated depression and anxiety were observed. These results support the hypothesis that HIV-related cognitive disturbance occurs within the context of immunosuppression.
Keywords: Adult AIDS Dementia Complex/*DIAGNOSIS/PSYCHOLOGY AIDS Serodiagnosis/PSYCHOLOGY AIDS-Related Complex/DIAGNOSIS Cohort Studies Homosexuality/PSYCHOLOGY Human HIV Infections/*DIAGNOSIS/PSYCHOLOGY HIV Seropositivity/DIAGNOSIS Longitudinal Studies Male *Neuropsychological Tests Prospective Studies Psychometrics Sick Role Support, Non-U.S. Gov't Wechsler Scales JOURNAL ARTICLEKWDadultaidsdementiacomplex/KWDdiagnosis/psychologyaidsserodiagnosis/psychologyaids-relatedcomplex/diagnosiscohortstudieshomosexuality/psychologyhumanhivinfections/KWDdiagnosis/psychologyhivseropositivity/diagnosislongitudinalstudiesmaleKWDneuropsychologicaltestsprospectivestudiespsychometricssickrolesupport,non-uKWDsKWDgov'twechslerscalesjournalarticle
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Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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