Incidence of the WAIS-R Fuld profile in HIV-1 infection. NLM AIDSLINE Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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Incidence of the WAIS-R Fuld profile in HIV-1 infection.

J Clin Exp Neuropsychol. 1990 Oct;12(5):807-11. Unique Identifier : AIDSLINE MED/91079238
van Gorp WG; Tulin SJ; Evans G; Satz P; West Los Angeles VA Medical Center, Neuropsychology Laboratory,; CA 90073.

Abstract: The incidence of a WAIS-R subtest marker sensitive to cholinergic dysfunction was assessed in a sample 116 homosexual males infected with HIV (Acquired Immunodeficiency Syndrome [AIDS] N = 40; AIDS Related Complex [ARC], N = 76). The incidence of positive profiles was low in the overall sample (11/116, 9%), and significantly lower than incidence rates reported for known cholinergic deficient groups (Alzheimer's disease; scopolamine). However, significantly more AIDS patients (8/40, 20%) than ARC patients (3/76, 4%) demonstrated positive profiles. These results suggest that, as a group, persons with ARC or AIDS do not show an increased incidence of the Fuld profile associated with cholinergic disruption, and offer continued support for diagnostic specificity of the Fuld formula for Alzheimer's disease.
Keywords: Acquired Immunodeficiency Syndrome/PHYSIOPATHOLOGY/PSYCHOLOGY Adult AIDS Dementia Complex/*PHYSIOPATHOLOGY/PSYCHOLOGY AIDS-Related Complex/PHYSIOPATHOLOGY/PSYCHOLOGY Brain/PHYSIOPATHOLOGY Cholinergic Fibers/*PHYSIOLOGY Homosexuality/PSYCHOLOGY Human HIV Infections/*PHYSIOPATHOLOGY/PSYCHOLOGY HIV-1/*PATHOGENICITY Middle Age Psychometrics Receptors, Cholinergic/*PHYSIOLOGY *Wechsler Scales JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/physiopathology/psychologyadultaidsdementiacomplex/KWDphysiopathology/psychologyaids-relatedcomplex/physiopathology/psychologybrain/physiopathologycholinergicfibers/KWDphysiologyhomosexuality/psychologyhumanhivinfections/KWDphysiopathology/psychologyhiv-1/KWDpathogenicitymiddleagepsychometricsreceptors,cholinergic/KWDphysiologyKWDwechslerscalesjournalarticle
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Copyright © 1991 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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