1990
- AIDS : facts and fears, crisis and controversy. [videorecording]
- [Mt. Kisco, N.Y.] : Guidance Associates, c1986 1 videocassette (57 min.) : sd., col. ; 1/2 in. + 1 guide + 2 handouts Unique Identifier : AIDSLINE AV/9000919A
- Pindyck J
- (Producer) Here s a video that explicitly presents how AIDS is transmitted - stressing the behaviors that put people at risk. Experts present evidence that there is little or no risk of contagion through blood transfusions and casual contact. Medical experts explain the clinical nature of the virus and how it attack
- One of our own. [videorecording]
- Chicago, Ill. : Dartnell Corp., c1987 1 videocassette (30 min.) : sd., col. ; 1/2 in. + 2 guides + 4 handouts + 1 poster Unique Identifier : AIDSLINE AV/9000930A
- (Producer) Since the first cases of AIDS were diagnosed, the fear of AIDS has spread almost as quickly as the disease itself. Even though the virus associated with AIDS is transmitted in only a limited number of identifiable ways, questions have been raised about possible exposure to the disease in the workplace. As
- [Hilfe vor AIDS : der AIDS-Report der Gesellschaft fur Naturheilkunde Deutschland e.V.]
- Munchen : Die Gesellschaft, c1986 94 p Unique Identifier : AIDSLINE CAT/9011179
- Wahler J
- Trends in sexually transmitted diseases in Western Australia, 1974-1987 : with special reference to effects of the AIDS public education campaign.
- Perth : Health Dept. of Western Australia, 1987 i, 29 leaves : ill Unique Identifier : AIDSLINE CAT/9010564
- Roberts M; Holman CD; Machin J
- AIDS and syphilis : the hidden link.
- Berkeley, Calif. : North Atlantic Books ; Washington, D.C. : Wehawken Book Co., c1987 xii, 132 p Unique Identifier : AIDSLINE CAT/9010619
- Coulter HL
- AIDS, the problem in Ireland.
- Dublin : Town House, 1987 141 p Unique Identifier : AIDSLINE CAT/9010621
- Freedman D
- The:AIDS book : information for workers. 3rd rev. ed.
- Calif.). AIDS Education Committee Washington, D.C. : Service Employees International Union (1313 L St., NW, Washington, DC 20005), 1988 96 p Unique Identifier : AIDSLINE CAT/9010312
- Administrator's guide to AIDS education.
- Chicago, Ill. : National Safety Council, c1988 31 p Unique Identifier : AIDSLINE CAT/9010598
- AIDS in Africa : the social and policy impact.
- Lewiston : Edwin Mellen Press, c1988 xxxi, 336 p. : ill (Studies in African health and medicine ; v. 10 [i.e. 1]) Unique Identifier : AIDSLINE CAT/9010620
- Miller NN; Rockwell RC
- Coping with AIDS : the public response to the epidemic.
- Dubuque, Iowa : Kendall/Hunt Pub. Co. ; Dayton, Ohio : National Issues Forms, [c1988] 44 p. : ill (National issues forums) Unique Identifier : AIDSLINE CAT/9010660
- Melville K
- Reports on aids in the African press : an annotated bibliography.
- Bloomington, IN : African Studies Program, Indiana University, [1988] 47 p Unique Identifier : AIDSLINE CAT/9010899
- Schmidt NJ
- Secretary's Work Group on Pediatric HIV Infection and Disease : final report.
- Work Group on Pediatric HIV Infection and Disease [Washington, D.C.] : Dept. of Health and Human Services ; Washington, DC : For sale by the Supt. of Docs., U.S. G.P.O., [1988] 92 p. : ill (NIH publication ; no. 89-3063) Unique Identifier : AIDSLINE CAT/9010908
- AIDS in gastroenterology and hepatology : proceedings of the First International Congress on the Gastrointestinal Tract and the Liver in the Acquired Immunodeficiency Syndrome, Munich, June 9-10, 1988.
- Grafelfing : Demeter Verlag, [1988?] ix, 77 p. : ill Unique Identifier : AIDSLINE CAT/9011051
- Classen M; Dancygier H; Liver in the Acquired Immunodeficiency Syndrome
- HIV infection in the brain.
- [Stockholm] : Dept. of Virology, Karolinska Institute, [1989] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9010064
- Chiodi F
- HIV infection : a prospective longitudinal study of clinical, immunological, and virological characteristics of the infection.
- Stockholm : Karolinska institute, 1989 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9010402
- Morfeldt-Manson L
- AIDS, Africa, and racism. [New and rev. ed.].
- London : Free Association Books, 1989 192 p Unique Identifier : AIDSLINE CAT/9011052
- Chirimuuta RC; Chirimuuta RJ
- Guidelines for prevention of transmission of human immunodeficiency virus and hepatitis B virus to health-care and public-safety workers : a response to P.L. 100-607, the Health Omnibus Programs Extension Act of 1988.
- Atlanta, Ga. : U.S. Dept. of Health and Human Services, Public Health Service, Centers for Disease Control, [1989] 46 p (DHHS (NIOSH) publication ; 89-107) Unique Identifier : AIDSLINE CAT/9011167
- Report.
- Pacific AIDS/HIV Infection Manila, Philippines : Printed and distributed by the Regional Office for the Western Pacific of the World Health Organization, 1989 28 p Unique Identifier : AIDSLINE CAT/9011323
- WorldAIDS. No. 1 (Jan. 1989)-
- London : Panos Institute in association with the Bureau of Hygiene and Tropical Diseases, c1989- v. : ill Unique Identifier : AIDSLINE CAT/9011394
- Economic aspects of AIDS and HIV infection.
- Berlin ; New York : Springer-Verlag, c1990 xvi, 364 p. : ill (Health systems research) Unique Identifier : AIDSLINE CAT/9010017
- Schwefel D; Committee on Health Services Research; (Gesellschaft fur Strahlen- und Umweltforschung)
- Planning for AIDS care.
- Chicago, IL : American Hospital Association, c1990 46 p. : ill Unique Identifier : AIDSLINE CAT/9010506
- Sandrick KM; McGrath DG; Reczynski DF; Neiman JS; and Marketing; and Marketing. Issues and Policy Committee
- AIDS and intravenous drug use : future directions for community-based prevention research.
- Rockville, MD (5600 Fishers Lane, Rockville, 20857) : U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse ; Washington, D.C. : For sale by the Supt. of Docs., U.S. G.P.O., 1990 xiv, 305 p. : ill (NIDA research monograph ; 93) Unique Identifier : AIDSLINE CAT/9011050
- Leukefeld CG; Battjes R; Amsel Z
- Rehabilitation for patients with HIV disease.
- New York : McGraw-Hill, Health Professions Division, c1991 xix, 507 p. : ill., form Unique Identifier : AIDSLINE CAT/9010618
- Mukand J
- TREATMENT OF BURKITT'S AND UNDIFFERENTIATED NON-BURKITT'S LYMPHOMA USING INTENSIFICATION HIGH-DOSE ARA-C AND EXTENDED CONSOLIDATION CHEMOTHERAPY. AN ECOG STUDY (MEETING ABSTRACT)
- Proc Annu Meet Am Soc Clin Oncol; 9:A1010 1990. Unique Identifier : AIDSLINE ICDB/90661789
- Mazza JJ; Hines JD; Anderson JW; O'Connell MJ; Marshfield Clinic, Marshfield, WI 54449
- 73 patients (pts) were entered into a protocol for treatment of Burkitt s and undifferentiated non-Burkitt s lymphoma (EST3484) consisting of induction chemotherapy (CTX 1.2 g/m2 day 1; Oncovin 1.4 mg/m2 days 3, 10, 17 and 24; MTX 300 mg/m2 iv day 12 followed by leucovorin rescue; prednisone 60 mg/m2 po days 3-30 with
- STUDIES ON TRANSACTIVATION BY HUMAN T CELL LEUKEMIA VIRUS
- Diss Abstr Int [B]; 50(9):3846 1990. Unique Identifier : AIDSLINE ICDB/90665700
- Kitado H; Univ. of California, Irvine
- We have inserted sequences from the human T-cell leukemia viruses (HTLVs) that are responsive to tax, into the long terminal repeats (LTRs) of Moloney murine leukemia virus (M-MuLV). The inserted HTLV sequences conferred tax-response to the Moloney promoter in transient expression assays whether or not the Moloney enh
- [Seroprevalence of HTLV-I virus in the general population of six Central African countries]
- Int Conf AIDS. 1989 Jun 4-9;5:47 (abstract no. M.A.O.16). Unique Identifier : AIDSLINE ICA5/00001689
- Delaporte E; Peeters M; Durand JP; Porte P; Audoin J; Josse R; Centre International de Recherches Medicales, BP 769; Franceville, Gabon
- [Free and anonymous French Screening Centers - evaluation of 2 Parisron centers - City of Paris]
- Int Conf AIDS. 1989 Jun 4-9;5:49 (abstract no. M.A.O.24). Unique Identifier : AIDSLINE ICA5/00002489
- Cavelier A; Ancelle-Park R; Helal H; Loygue J; Poinsard R; Pretet S; D.A.S.E.S., Paris, France
- [Prevalence of HIV Infections and pulmonary Tuberculosis in an asymptomatic population in Haiti]
- Int Conf AIDS. 1989 Jun 4-9;5:50 (abstract no. M.A.O.29). Unique Identifier : AIDSLINE ICA5/00002989
- Lassegue A; Elie R; Hippolithe R; Cesar D; Cesar M; Centre Medical de Port-au-Prince, P-au-P, Haiti
- [Study of the risks of contamination by hepatitis B and HIV-1 virus in prison]
- Int Conf AIDS. 1989 Jun 4-9;5:52 (abstract no. M.A.O.40). Unique Identifier : AIDSLINE ICA5/00004189
- Espinoza P; Balian P; Bouchard I; Hopital de Fresnes Alle des Thuyas 94261 Fresnes Cedex France
- [Impact of the new definition of AIDS in Barcelona: the role of the tuberculosis patient]
- Int Conf AIDS. 1989 Jun 4-9;5:55 (abstract no. T.A.O.3). Unique Identifier : AIDSLINE ICA5/00005389
- Cayla JA; Plasencia A; Batalla J; Parellada N; Jansa JM; Institut Municipal de la Salut. Barcelona. Spain
- [HIV-1 and HIV-2 in a Dakar prison (Senegal)]
- Int Conf AIDS. 1989 Jun 4-9;5:81 (abstract no. M.A.P.19). Unique Identifier : AIDSLINE ICA5/00017589
- Samb ND; Boye CS; Diouf G; Siby T; Sow A; M'Boup S; Universite de Dakar, Senegal
- [Incidence of Hospitalization and HIV infections in prison]
- Int Conf AIDS. 1989 Jun 4-9;5:81 (abstract no. M.A.P.24). Unique Identifier : AIDSLINE ICA5/00018089
- Bouchard I; Espinoza P; Stein S; Polo Devoto J; D'Havillivillee P; Benamouzig R; Hopital de Fresnes (EHPNF) Allee des Thuyas 94261 Fresnes Cedex; France
- [Epidemiology of AIDS in prison]
- Int Conf AIDS. 1989 Jun 4-9;5:82 (abstract no. M.A.P.25). Unique Identifier : AIDSLINE ICA5/00018189
- Espinoza P; Bouchard I; Atkhen P; Polo DJ; Hopital de Fresnes (EHPNF) Allee des Thuyas 94261 Fresnes France
- [HIV seropositivity in blood donors and estimation of residual risk in transfusion]
- Int Conf AIDS. 1989 Jun 4-9;5:83 (abstract no. M.A.P.33). Unique Identifier : AIDSLINE ICA5/00018989
- Courouce AM; Groupe de travail Retrovirus de la Societe Nationale de; Transfusion Sanguine - Paris France
- HIV-1 infection in New York City STD clinic patients: evidence for stable seroprevalence, 1987-1988.
- Int Conf AIDS. 1989 Jun 4-9;5:89 (abstract no. M.A.P.67). Unique Identifier : AIDSLINE ICA5/00022489
- Weisfuse IB; Chiasson MA; Back S; Ramirez L; Greenberg B; Ewing W; New York City Department of Health, NY, NY. USA
- OBJECTIVE: To determine HIV-1 seroprevalence in patients at New York City STD clinics, and to compare rates over time in one clinic. METHODS: Blinded serosurveys were conducted among STD clinic patients in one clinic in 1987 and in all 12 STD clinics in 1988. The interval between the 2 surveys was 18 months. Specimens
- Characterization of HIV infected STD clinic clients identified through routine voluntary screening: implications for future health care needs.
- Int Conf AIDS. 1989 Jun 4-9;5:89 (abstract no. M.A.P.68). Unique Identifier : AIDSLINE ICA5/00022589
- Erickson B; Glasser D; Wasserheit JN; Rompalo AM; Brathwaite W; Hook EW; Baltimore City Health Dept., Baltimore, USA
- OBJECTIVE: To describe demographic and historical characteristics of HIV infected patients identified by a routine voluntary screening program in Baltimore STD clinics. METHODS: Consenting patients are screened for HIV-1 using commercially available EIA, confirmed using a licensed Western Blot test, and are given appo
- Frequency of HIV infection among patients of STD out-patient clinic.
- Int Conf AIDS. 1989 Jun 4-9;5:89 (abstract no. M.A.P.69). Unique Identifier : AIDSLINE ICA5/00022689
- Stapinski A; Mazurkiewicz W; Wojtowicz U; Napiorkowska T; Babiuch L; Medical Academy Warsaw, Poland
- OBJECTIVE: The incidence of HIV antibodies has been investigated in 1327 patients with various STD, 1022 males and 305 females, seen in the STD out-patient clinic. Sixty six males/6.5%/ were homosexuals or bisexuals. METHODS: The HIV antibodies were tested by the EIA method, and positive tests were confirmed by the We
- Analysis of trends over time in client characteristics at Minnesota (MN) HIV-1 antibody counseling and testing sites.
- Int Conf AIDS. 1989 Jun 4-9;5:89 (abstract no. M.A.P.70). Unique Identifier : AIDSLINE ICA5/00022789
- Danila R; Shultz J; Osterholm M; Henry K; Simpson M; MacDonald K; MN Dept. of Health, MN, USA
- OBJECTIVE: To evaluate the role of Minnesota HIV-1 antibody counseling and testing site programs (CTS) in HIV-1 transmission prevention efforts. METHODS: CTS client demographic and risk factor data were analyzed for 18,483 CTS clients with HIV-1 serology from 7/85-6/88. RESULTS: The highest seroprevalence rates were i
- Blind HIV-ab and syphilis-ab seroprevalence survey in New York State STD clinics.
- Int Conf AIDS. 1989 Jun 4-9;5:89 (abstract no. M.A.P.71). Unique Identifier : AIDSLINE ICA5/00022889
- DiFerdinando G; Arthur K; Hipp S; Murphy D; New York State (NYS) Department of Health, Albany, NY, USA
- OBJECTIVE: To monitor over time the HIV and syphilis seroprevalence among STD clients in all regions of NYS, excluding NYC. METHODS: Sera of clients receiving syphilis testing (RPR, FTA) at 19 STD clinics in 8 NYS counties during 1988 were tested anonymously for HIV (ELISA, WB). Clients were excluded if they had been
- HIV-1 infection in persons attending sexually transmitted disease (STD) clinics in Minnesota (MN).
- Int Conf AIDS. 1989 Jun 4-9;5:90 (abstract no. M.A.P.72). Unique Identifier : AIDSLINE ICA5/00022989
- Danila R; Henry K; Simpson M; Osterholm M; MacDonald K; MN Dept. of Health, MN, USA
- OBJECTIVE: To determine HIV-1 seroprevalence and risk factors associated with infection in persons attending STD clinics in Minnesota. METHODS: 1094 patients attending two STD clinics from 4/1/88-11/1/88 were systematically selected; participants were interviewed for HIV-1 infection risks and had blood drawn for HIV-1
- HIV seroprevalence of STD clinics in Houston, Texas, USA.
- Int Conf AIDS. 1989 Jun 4-9;5:90 (abstract no. M.A.P.73). Unique Identifier : AIDSLINE ICA5/00023089
- Enochs M; Falletti RL; Sullivan K; Sanchez D; Penaloza D; Honeycutt H; Bureau of Epidemiology, Houston Dept. of Health & Human Services,; Houston, Texas, USA
- OBJECTIVE: To present statistical data supporting the growing threat of HIV infection within specific sexually active populations attending an STD clinic. METHODS: A blinded survey was conducted at a large STD clinic servicing a predominantly black area of Houston. All blood samples taken for standard RPR screening we
- HIV seroprevalence in sexually transmitted disease clinics in Los Angeles County.
- Int Conf AIDS. 1989 Jun 4-9;5:90 (abstract no. M.A.P.74). Unique Identifier : AIDSLINE ICA5/00023189
- Ford WL; Rose T; Kerndt P; Onorato I; Waterman S; Los Angeles County Department of Health Services, Los Angeles,; California, USA
- OBJECTIVE: To estimate the seroprevalence of human immunodeficiency virus (HIV) among patients attending sexually transmitted disease (STD) clinics in Los Angeles County (LAC). METHODS: Between July and December 1988, consecutive attendees at 4 public STD clinics were screened for HIV Ab. Repeat ELISA positives were c
- Development and funding of public HIV counseling and testing services in the United States.
- Int Conf AIDS. 1989 Jun 4-9;5:90 (abstract no. M.A.P.75). Unique Identifier : AIDSLINE ICA5/00023289
- Cahill K; Bowen G; Kirby C; Centers for Disease Control (CDC), Atlanta, GA, USA
- OBJECTIVE: To describe the history and development of public sector funded HIV counseling and testing (CT) services in the U.S. since 1985. METHOD: We reviewed quarterly reports from State HIV/AIDS prevention programs and the CDC funding awards of State AIDS prevention cooperative agreements in order to document fundi
- Incidence of HIV infection in gay and bisexual men attending a counseling and testing site or an AIDS prevention program.
- Int Conf AIDS. 1989 Jun 4-9;5:90 (abstract no. M.A.P.76). Unique Identifier : AIDSLINE ICA5/00023389
- Cohn D; Koleis J; Cooper S; Cole V; Judson F; Denver Disease Control Service, Denver, CO, USA
- OBJECTIVE: To determine incidence of HIV infection in gay and bisexual men (GM) using a counseling and testing site (CTS) or enrolled in an AIDS Prevention longitudinal cohort study (APS). METHODS: GM who attended Denver s voluntary CTS from July, 1985 through December, 1988, and GM enrolled in APS from January, 1987
- HIV2 infection: some clinical and epidemiological aspects in Portugal.
- Int Conf AIDS. 1989 Jun 4-9;5:90 (abstract no. M.A.P.77). Unique Identifier : AIDSLINE ICA5/00023489
- Botas J; Tavares L; Carvalho C; Feliciano H; Antunes F; Dep. Inf. Diseases, Hosp. Sta Maria, Lisboa, Portugal
- OBJECTIVE: To assess the frequency of HIV2 infection in HIV seropositives studied at our Department. METHODS: The charts of 225 HIV seropositives (ELISA and Western blot) were analysed. Tests for HIV2 were performed in HIV1 negatives with disease, sexual partners of HIV2 positives or possibility of infection in Africa
- HIV-2 in Italy: no evidence, yet.
- Int Conf AIDS. 1989 Jun 4-9;5:91 (abstract no. M.A.P.78). Unique Identifier : AIDSLINE ICA5/00023589
- Cadeo GP; Corda L; Pizzocolo G; Albertini A; Carosi G; Dept. of Infectious Tropical Diseases, Dept. Chemistry,; University of Brescia, Brescia, Italy
- OBJECTIVE: The authors have carried out a wide-scale seroepidemiological survey in the region of Lombardy ( Italy ) to verify the presence of HIV-2 infection among risk categories. METHODS: 1069 subjects (946 drugs addicts, 80 homosexuals, 25 haemophiliacs and sexual partners) have be
- [Effectiveness of HIV-2 blood screening]
- Int Conf AIDS. 1989 Jun 4-9;5:92 (abstract no. M.A.P.85). Unique Identifier : AIDSLINE ICA5/00024289
- Courouce AM; groupe de travail Retrovirus de la Societe Nationale de; Transfusion Sanguine - Paris, France
- [Surveillance - health education of prostitutes in Senegal]
- Int Conf AIDS. 1989 Jun 4-9;5:97 (abstract no. M.A.P.117). Unique Identifier : AIDSLINE ICA5/00027389
- Siby T; Thior I; Sankale JL; Ndoye I; Gueye A; Mboup S; Bacterio-Virologie/Universite de Dakar
- [Control of quality in commercialized anti-HIV kits in France]
- Int Conf AIDS. 1989 Jun 4-9;5:97 (abstract no. M.A.P.118). Unique Identifier : AIDSLINE ICA5/00027489
- North M; Mouillot L; Courouce AM; Societe Nationale de Transfusion Sanguine, France
- [Evaluation of significance of a test using synthetic peptides (immunocomb) for the serologic diagnosis of HIV infections]
- Int Conf AIDS. 1989 Jun 4-9;5:97 (abstract no. M.A.P.119). Unique Identifier : AIDSLINE ICA5/00027589
- Rosenheim M; Ritterband M; Kerouedan D; Schwartz Y; M'Pele P; Gentilini M; Dpt de Medecine Tropicale et Unite INSERM 313, Hopital; Salpetriere, 47 Bd de 1'Hopital, 75013 Paris, France
- [HIV-1 virus in sickle cell anemia children after multiple transfusions in yaounde (Cameroun)]
- Int Conf AIDS. 1989 Jun 4-9;5:99 (abstract no. T.A.P.1). Unique Identifier : AIDSLINE ICA5/00027689
- Tetanye E; Nyouma E; Ndumbe P; Kaptue-Noche L; Centre Universitaire des Sciences de la Sante
- [Diffusion of sexual precautions and evolution of seropositivity in a french homosexual population: 1985 - 1988]
- Int Conf AIDS. 1989 Jun 4-9;5:102 (abstract no. T.A.P.19). Unique Identifier : AIDSLINE ICA5/00029489
- Pollak M; Schiltz MA; Boisson P; CNRS-GSPM, Paris
- [Hospital Surveillance of HIV infections in Bordeaux, France epidemiologic trends, 1985-1988]
- Int Conf AIDS. 1989 Jun 4-9;5:103 (abstract no. T.A.P.25). Unique Identifier : AIDSLINE ICA5/00030089
- Chaslerie A; Dupon M; Morlat P; Lacoste D; Pellegrin JL; Departement d'Informatique Medicale, Universite de Bordeaux; II, Bordeaux, France
- [Heterosexual transmission of HIV infections in sex partners of HIV seropositive drug abusers]
- Int Conf AIDS. 1989 Jun 4-9;5:117 (abstract no. T.A.P.111). Unique Identifier : AIDSLINE ICA5/00038689
- Errante I; Orso M; Meini M; Caggese L; Ferrazzi D; Schlacht I; Hopital Niguarda Ca' Granda-Milan
- [Analysis of trends in socio - demographic characteristics in AIDS cases reported in France]
- Int Conf AIDS. 1989 Jun 4-9;5:124 (abstract no. W.A.P.25). Unique Identifier : AIDSLINE ICA5/00042089
- Laporte A; Hubert B; Marciniak A; Cluzan S; Brunet JB; Direction Generale de la Sante, Paris, France
- [Outcome of HIV infected subjects: 1st results of a hospital surveillance]
- Int Conf AIDS. 1989 Jun 4-9;5:129 (abstract no. W.A.P.60). Unique Identifier : AIDSLINE ICA5/00045589
- Dabis F; Commenges D; Chene G; Pellegrin JL; Schmitt A; Departement d'Informatique Medicale, Universite de Bordeaux; II, France
- [HTLV-I in metropolitan France]
- Int Conf AIDS. 1989 Jun 4-9;5:147 (abstract no. Th.A.P.3). Unique Identifier : AIDSLINE ICA5/00051889
- Lemaire JM; Coste J; Courouce AM; CRTS - 34010 Montpellier, France
- [HIV-1 and HIV-2 coinfections in Martinique]
- Int Conf AIDS. 1989 Jun 4-9;5:145 (abstract no. Th.A.P.30). Unique Identifier : AIDSLINE ICA5/00054489
- Neisson-Vernant C; Monplaisir N; Chout R; Sobesky G; Demeleumesster R; Cales-Quist D; CHRU Fort-de-France
- [Adjustment of chronologic models with separation of the discriminant function]
- Int Conf AIDS. 1989 Jun 4-9;5:157 (abstract no. Th.A.P.99). Unique Identifier : AIDSLINE ICA5/00061389
- Prum B; Picard D; Rozenbaum W; Garbanzadeh D; Guihenneuc C; Universite Paris V
- [3 year surveillance of T4 lymphocytes and B2 microglobulin in a cohort of 166 subjects infected with HIV]
- Int Conf AIDS. 1989 Jun 4-9;5:166 (abstract no. A.531). Unique Identifier : AIDSLINE ICA5/00066589
- Brugnetti A; Negre M; Pesce A; Fuzibet JG; Quaranta JF; Dujardin P; Cassuto JP; C.H.R.U. de Nice, France
- [Modifications and geographical variations in transmission groups of HIV infections in France]
- Int Conf AIDS. 1989 Jun 4-9;5:167 (abstract no. A.539). Unique Identifier : AIDSLINE ICA5/00067389
- Jestin C; Ligue Francaise pour la Prevention des Maladies Infectieuses,; France
- [HIV, syphilis and drug abuse]
- Int Conf AIDS. 1989 Jun 4-9;5:168 (abstract no. A.543). Unique Identifier : AIDSLINE ICA5/00067789
- Espinoza P; Loubeyre JL; Benamouzig R; Bouchard I; Etablissement d'Hospitalisation Public National de Fresnes,; France
- [Epidemiological profile of infections due to human immunodeficiency virus (HIV) in Estrie]
- Int Conf AIDS. 1989 Jun 4-9;5:168 (abstract no. A.547). Unique Identifier : AIDSLINE ICA5/00068189
- Duperval R; Boivin D; Marcoux JA; Lepine M; Saad WP; Universite de Sherbrooke, Sherbrooke, Quebec, Canada
- [Coinfection with HIV-1 and HTLV-I]
- Int Conf AIDS. 1989 Jun 4-9;5:169 (abstract no. A.552). Unique Identifier : AIDSLINE ICA5/00068689
- Patey O; N'Go N; Dublanchet A; Lafaix C; Service des maladies infectieuses et tropicales, Villeneuve St; Georges-France
- [Evaluation of susceptibility to AIDS prevention in university students in Aix-Marseille]
- Int Conf AIDS. 1989 Jun 4-9;5:170 (abstract no. A.557). Unique Identifier : AIDSLINE ICA5/00069189
- Beresniak A; Enel P; Sambuc R; San Marco JL; Laboratoire de Sante Publique, Faculte de Medecine, Marseille,; France
- [Actual absence of HIV2 in Brazzaville (Congo)]
- Int Conf AIDS. 1989 Jun 4-9;5:172 (abstract no. A.558). Unique Identifier : AIDSLINE ICA5/00070289
- Yala F; Biendo M; Madzouka J; Copin N; Carme B; CHU BrazzavilleBP32, Brazzaville, Congo
- [IM-9 classification for HIV infections in the french experience of hospital morbidity]
- Int Conf AIDS. 1989 Jun 4-9;5:172 (abstract no. A.571). Unique Identifier : AIDSLINE ICA5/00070589
- Boulay F; Pibarot ML; Jestin C; Laporte A; Brunet JB; Direction des Hopitaux, Paris, France
- [High prevalence of HTLV-I and low prevalence of HIV in ivory coast lepers]
- Int Conf AIDS. 1989 Jun 4-9;5:175 (abstract no. A.587). Unique Identifier : AIDSLINE ICA5/00072189
- Sangare A; Verdier M; Sorro B; Gershy-Damet GM; Leonard G; Fran:cois D; Institut Pasteur et, Cote d'Ivoire
- [The demand for HIV serology examination in general medicine]
- Int Conf AIDS. 1989 Jun 4-9;5:176 (abstract no. A.595). Unique Identifier : AIDSLINE ICA5/00072889
- Van Casteren V; Stroobant A; Institut D'hygiene ET D'epidemiologie, Bruxelles, Belgique
- [Heterosexual transmission of HIV: hospital surveillance in Aquintaine, France - 1985-88]
- Int Conf AIDS. 1989 Jun 4-9;5:183 (abstract no. A.635). Unique Identifier : AIDSLINE ICA5/00076589
- Poumerol G; Chaslerie A; Morlat P; Lacoste D; Dupon M; Department d'Informatique Medicale, Universite de Bordeaux II,; Bordeaux, France
- [Epidemiological characteristics of new HIV seropositives in central-western France: evaluation of incidence and behavior]
- Int Conf AIDS. 1989 Jun 4-9;5:183 (abstract no. A.636). Unique Identifier : AIDSLINE ICA5/00076689
- Marchand S; Choutet P; CHRU Bretonneau, 37044 Tours France
- [Treatment of cerebral toxoplasmosis with clindamycin and 5-fluorouracil]
- Int Conf AIDS. 1989 Jun 4-9;5:193 (abstract no. M.B.O.36). Unique Identifier : AIDSLINE ICA5/00080589
- Eliaszewicz M; Kirstetter M; Meyohas MC; Frottier J; Hopital Saint-Antoine, Paris, France
- [Effects of prophylactic pentamidine aerosols on respiratory function in mid term]
- Int Conf AIDS. 1989 Jun 4-9;5:196 (abstract no. T.B.O.2). Unique Identifier : AIDSLINE ICA5/00082189
- Camus F; de Picciotto C; Lepretre A; Landman R; Girard PM; Saimot AG; Hopital Bichat-Claude Bernard, Paris, France
- [Study comparing the prevalence of HIV-1, HIV-2, and HTLV-I in lepers in 4 countries: Ivory Coast, Congo, Senegal, Yemen]
- Int Conf AIDS. 1989 Jun 4-9;5:197 (abstract no. T.B.O.9). Unique Identifier : AIDSLINE ICA5/00082889
- Mireille V; Sangare A; Sassou-Guesseau E; Gaye A; Al-Qubati Y; Denis F; Virologie et Neurologie CHU Dupuytren Limoges, France
- [Immunomodulators: alternative therapy associated with HIV infections]
- Int Conf AIDS. 1989 Jun 4-9;5:198 (abstract no. T.B.O.15). Unique Identifier : AIDSLINE ICA5/00083489
- Pompidou A; Faculte de Medecine Cochin Port Royal Paris
- [Circulating HIV-1 antigens]
- Int Conf AIDS. 1989 Jun 4-9;5:202 (abstract no. T.B.O.32). Unique Identifier : AIDSLINE ICA5/00085189
- Rouzioux C; Hopital Necker-Enfants Malades, Paris, France
- [Bacterial and viral pneumonias in AIDS patients who use I.V. drugs]
- Int Conf AIDS. 1989 Jun 4-9;5:214 (abstract no. Th.B.O.13). Unique Identifier : AIDSLINE ICA5/00092089
- Mouton Y; Chidiac C; Senneville E; Service Regional des Maladies Infectieuses, Centre Hospitalier; F-59208 Tourcoing, France
- Isoprinosine reduced clinical progression in HIV infected patients in a double blind placebo controlled study.
- Int Conf AIDS. 1989 Jun 4-9;5:219 (abstract no. Th.B.O.46). Unique Identifier : AIDSLINE ICA5/00095189
- Hidovre, Denmark
- OBJECTIVE: To determine the influence of isoprinosine (Imunovir) on the clinical course of HIV infection. METHODS: A total of 866 HIV infected patients from Sweden and Denmark were randomised and
- [Comparison of performances of ELISA reactants using a recombinant peptide for detection of HIV-2 infections]
- Int Conf AIDS. 1989 Jun 4-9;5:221 (abstract no. Th.B.O.55). Unique Identifier : AIDSLINE ICA5/00095989
- Catalan F; Milovanovic A; Ly TD; Odehouri K; Moreau J; Kadiot A; Institut Alfred Fournier - Paris - France
- [Epidemiological characteristics and clinical evolution of 45 pregnant patients seropositive for HIV]
- Int Conf AIDS. 1989 Jun 4-9;5:227 (abstract no. M.B.P.32). Unique Identifier : AIDSLINE ICA5/00099589
- Parnet-Mathieu F; Meyohas MC; Vincenti O; Barrat J; Eliaszewicz M; Brossard Y; Centre d'Hemobiologie Perinatale
- [Contribution of the CAT scan in diagnosing pulmonary complications of AIDS in the adult]
- Int Conf AIDS. 1989 Jun 4-9;5:228 (abstract no. M.B.P.41). Unique Identifier : AIDSLINE ICA5/00100489
- Trotot PM; Sandoz-Tronca C; Marichez M; Levillain R; Institut Pasteur
- [Diagnosis and treatment of cervico-vaginal and vulvar papilloma virus lesions in women seropositive for HIV virus]
- Int Conf AIDS. 1989 Jun 4-9;5:231 (abstract no. M.B.P.55). Unique Identifier : AIDSLINE ICA5/00101889
- Caubel P; Foulques H; Blondon J; Lefranc JP; Hopital de la Salpetriere, Paris, France
- [African disseminated histoplasmosis in a black child from Guinea-Bissau, seropositive for HIV-2]
- Int Conf AIDS. 1989 Jun 4-9;5:235 (abstract no. M.B.P.82). Unique Identifier : AIDSLINE ICA5/00104589
- Matos Almeida MJ; Service Dermatologie, Hosp. Sta Maria, Lisbonne Portugal
- [Pharmacokinetics (blood-spinal fluid) of large doses of acyclovir in HIV patients intravenous]
- Int Conf AIDS. 1989 Jun 4-9;5:236 (abstract no. M.B.P.88). Unique Identifier : AIDSLINE ICA5/00105189
- Chavanet P; Buisson M; Lokiec P; Aho S; Bielefeld P; Waldner A; Portier H; Hopital du Bocage, BP1542, 21034 Dijon cedex
- [Cryptococcosis, histoplasmosis and AIDS in the Congo]
- Int Conf AIDS. 1989 Jun 4-9;5:237 (abstract no. M.B.P.91). Unique Identifier : AIDSLINE ICA5/00105489
- Carme B; Mbitsi A; Ngolet A; Itoua-Ngaporo A; Ebikili B; Aya GM; Centre Hospitalier et Universitaire de Brazzaville, Congo
- [Transmission of HIV-1 by transfusion: a decreasing risk]
- Int Conf AIDS. 1989 Jun 4-9;5:247 (abstract no. M.B.P.151). Unique Identifier : AIDSLINE ICA5/00111489
- Jullien AM; Courouce AM; Richard D; Girard M; Elghouzzi MH; Habibi B; Fondation Nationale de Transf. Sang., Paris, France
- [Blood HIV antigens: systematic screening of blood donors in the parision region]
- Int Conf AIDS. 1989 Jun 4-9;5:247 (abstract no. M.B.P.154). Unique Identifier : AIDSLINE ICA5/00111789
- Vignon D; Transfustion Hopital Foch, Suresnes, France
- [Varicella and HIV infection]
- Int Conf AIDS. 1989 Jun 4-9;5:251 (abstract no. M.B.P.179). Unique Identifier : AIDSLINE ICA5/00114289
- Perronne C; Lazanas M; Leport C; Salmon D; Bricaire F; Vilde JL; Hopital Claude-Bernard, 75018 Paris, France
- [Cutaneous and veneral manifestations in patients infected with HIV in French Guiana]
- Int Conf AIDS. 1989 Jun 4-9;5:252 (abstract no. M.B.P.181). Unique Identifier : AIDSLINE ICA5/00114489
- Pradinaud R; Sainte-Marie D; Centre Hospitalier de Cayenne, Cayenne, Guyanne Fran:caise
- [Cutaneous and mucous membrane manifestations of African AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:252 (abstract no. M.B.P.183). Unique Identifier : AIDSLINE ICA5/00114689
- Coll AM; Ball MD; Benga E; Fatyndiaye C; Fayendao MA; Feller-Dansokho E; C.H.U. de Dakar, Service des Maladies infectieuses
- [Cutaneous manifestations of HIV infections in Rwanda]
- Int Conf AIDS. 1989 Jun 4-9;5:253 (abstract no. M.B.P.188). Unique Identifier : AIDSLINE ICA5/00115189
- Harelimana F; Bugingo G; Hopital Universitaire, Butare, Rwanda
- [Clinical aspects of HIV-1 and HIV-2 and classification by Bangui]
- Int Conf AIDS. 1989 Jun 4-9;5:254 (abstract no. M.B.P.195). Unique Identifier : AIDSLINE ICA5/00115889
- Sow AB; Coll AM; Fayendao MA; Diouf G; Feller-Dansokho E; Diop BM; Service des Maladies Infectieuses, C.H.U. de Dakar, Senegal
- [Surveillance by magnetic resonance imaging since October 1986 of a cohort of 50 HIV patients, initially asymptomatic]
- Int Conf AIDS. 1989 Jun 4-9;5:254 (abstract no. M.B.P.196). Unique Identifier : AIDSLINE ICA5/00115989
- Trotot PM; Cabanis EA; Lavayssiere R; Cabee AE; Thibierge M; Bigot JM; Vignaud J; Sandoz-Tronca C; Sansonetti PJ; Levillain R; et al; Institut Pasteur, Paris, France
- [Study of the protein S during an HIV infection]
- Int Conf AIDS. 1989 Jun 4-9;5:254 (abstract no. M.B.P.197). Unique Identifier : AIDSLINE ICA5/00116089
- Lebret-Lerolle D; Pulik M; Jari L; Teillet-Thiebaud F; Cannesson G; Teillet F; Hopital Louis Mourier, Colombes, France
- [Ocular toxoplasmosis during AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:259 (abstract no. M.B.P.225). Unique Identifier : AIDSLINE ICA5/00118889
- Fegueux S; Sazoun L; Matheron S; de Truchis P; Couland JP; Saimot AG; Hopital Bichat-Claude Bernard, Paris, France
- [Ocular toxoplasmosis during AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:259 (abstract no. M.B.P.226). Unique Identifier : AIDSLINE ICA5/00118989
- Chakroun M; Meyohas MC; Pelosse B; Zazoun L; Vacherot B; Leport C; Hopital Claude Bernard, Paris, France
- [Thrombotic microangiopathy and HIV infection]
- Int Conf AIDS. 1989 Jun 4-9;5:263 (abstract no. M.B.P.249). Unique Identifier : AIDSLINE ICA5/00121289
- Khuong M; De Truchis P; Oksenhendler E; Matheron S; Dosquet P; Clauvel JP; Hopital Bichat-Claude Bernard, Paris, France
- [Prospective study on coagulation anomalies in 156 consecutive patients seropositive for HIV]
- Int Conf AIDS. 1989 Jun 4-9;5:263 (abstract no. M.B.P.250). Unique Identifier : AIDSLINE ICA5/00121389
- Taillan B; Roul C; Fuzibet JG; Vinti H; Pesce A; Bayle J; Cassuto JP; Dujardin P; C.H.R.U. de Nice, France
- [Are chronic lymphadenopathies evidence of an aggravation of the immunodeficiency tied to HIV? Cohort study of 264 seropositive subjects, Bordeaux, France]
- Int Conf AIDS. 1989 Jun 4-9;5:264 (abstract no. M.B.P.254). Unique Identifier : AIDSLINE ICA5/00121789
- Morlat P; Lacoste D; Msellati P; Dupon M; Pellegrin JL; Centre Hospitalier Regional Universitaire (CHRU), Bordeaux,; France
- [Nursing care and the AIDS epidemic]
- Int Conf AIDS. 1989 Jun 4-9;5:274 (abstract no. M.B.P.316). Unique Identifier : AIDSLINE ICA5/00127989
- Schneeberger C; Assistance Publique, Villejuif, France
- [Evaluation of active T lymphocytes and natural killer subpopulations during treatment of ARC patients with zidouudine]
- Int Conf AIDS. 1989 Jun 4-9;5:279 (abstract no. M.B.P.347). Unique Identifier : AIDSLINE ICA5/00131089
- Levacher M; Dournon E; Tallet S; Rouveix B; Pocidalo JJ; INSERM U.13, 10, Avenue de la Porte d'Aubervilliers 75944 Paris,; France
- [In the patient, only a fraction of the retrovirus infection seems sensitive to AZT]
- Int Conf AIDS. 1989 Jun 4-9;5:280 (abstract no. M.B.P.350). Unique Identifier : AIDSLINE ICA5/00131389
- Mathez D; Leibowitch J; Cesari D; Belilovsky C; Gorin I; Deleuze J; Paul D; Hopital Raymond-Poincare/Universite Rene-Descartes,; Garches/Paris-ouest, France
- [Prevalence of psychiatric disorders in patients hospitalized for AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:286 (abstract no. M.B.P.384). Unique Identifier : AIDSLINE ICA5/00134789
- Zamperetti M; Ferrazzi D; Schlacht I; Cusini M; Muratori S; Zerboni R; Servizio Psichiatrico Origgi I (Responsible Prof.G.F.Goldwurn); Ospedale Ca Granda Niguarda - Milano - Italy
- [Quantitative evaluation of parasitism in pneumocytosis in patients with AIDS or other immunodepressions]
- Int Conf AIDS. 1989 Jun 4-9;5:287 (abstract no. T.B.P.1). Unique Identifier : AIDSLINE ICA5/00134889
- Roux P; Parrot A; Denis M; Mayaud C; Parquin F; Lancastre F; Hopital Tenon - 4, rue de la chine - 75020 - Paris
- [Significance and limitations of induced expectorations in the diagnosis of AIDS pneumocytosis]
- Int Conf AIDS. 1989 Jun 4-9;5:287 (abstract no. T.B.P.4). Unique Identifier : AIDSLINE ICA5/00135189
- Delacour T; Roux P; Camus F; Fay M; Denis M; Girard PM; Hopital Tenon, Paris, France
- [Pneumocystosis and AIDS in Brazzaville, Congo]
- Int Conf AIDS. 1989 Jun 4-9;5:290 (abstract no. T.B.P.19). Unique Identifier : AIDSLINE ICA5/00136689
- Carme B; Mboussa J; Mpele P; Datry A; Mouanga-Yidika G; Itoua-Ngaporo A; Centre Hospitalier et Universitaire de Brazzaville, Congo
- [Treatment of AIDS pneumocystosis with DFMO]
- Int Conf AIDS. 1989 Jun 4-9;5:291 (abstract no. T.B.P.27). Unique Identifier : AIDSLINE ICA5/00137489
- Girard PM; Garou A; Rozenbaum W; Perronne C; Wolff M; Coulaud JP; Hopital Bichat - Claude Bernard, Paris, France
- [Treatment of pneumocystosis with cotrimoxazole]
- Int Conf AIDS. 1989 Jun 4-9;5:293 (abstract no. T.B.P.41). Unique Identifier : AIDSLINE ICA5/00138889
- Traore B; Eckert D; Rosenheim M; Gentilini M; Department de Medecine Tropicale, Sante Publique et; Parasitologie Universite de Paris VII. France
- [Use of fansidar for pneumocystosis and toxoplasmosis prophylaxis]
- Int Conf AIDS. 1989 Jun 4-9;5:294 (abstract no. T.B.P.47). Unique Identifier : AIDSLINE ICA5/00139489
- Livrozet JM; Mounilaila K; Garin JP; Mojon M; Garnier JL; Touraine JL; Hopital E. Herriot, PAV.P, Place D'arsonval, 69437 Lyon CX3; France
- [Prevention of pneumocystosis recurrence by pentamidine aerosols: prospective randomized study of AIDS patients treated by AZT]
- Int Conf AIDS. 1989 Jun 4-9;5:295 (abstract no. T.B.P.49). Unique Identifier : AIDSLINE ICA5/00139689
- Girard PM; Landman R; Gaudebout C; Lepretre A; Michon C; Saimot AG; Hopital Bichat - Claude Bernard, Paris, France
- [Secondary prophylaxis of pulmonary pneumocytosis with aerosol pentamidine]
- Int Conf AIDS. 1989 Jun 4-9;5:298 (abstract no. T.B.P.71). Unique Identifier : AIDSLINE ICA5/00141889
- Eliaszewicz M; Lacassin F; Lebas J; Meyohas MC; Perrin M; Picard O; Hopital Saint-Antoine, Paris, France
- [Effectiveness and safety in aerosol pentamidine prophylaxis in Italian I.V. drug abusers affected by AIDS, in zidovudine therapy]
- Int Conf AIDS. 1989 Jun 4-9;5:298 (abstract no. T.B.P.74). Unique Identifier : AIDSLINE ICA5/00142189
- Gafa S; Giudici MG; Vezzani F; Tuzza A; Calonghi GF; Malattie Infettive, Arcispedale S.Maria Nuova, Reggio Emilia,; Italy
- [Blood HIV antigens during the first infection]
- Int Conf AIDS. 1989 Jun 4-9;5:301 (abstract no. T.B.P.90). Unique Identifier : AIDSLINE ICA5/00143789
- Schiavini D; Puel J; Averous S; Bazex J; Laboratoire de Virologie, CHU Purpan, Toulouse, France
- [Aptitude of a rapid test for anti HIV and agglutination tests for detecting anti-HIV-2 antibodies in Senegal]
- Int Conf AIDS. 1989 Jun 4-9;5:304 (abstract no. T.B.P.105). Unique Identifier : AIDSLINE ICA5/00145289
- Mboup S; Sankale JL; Kabeya CM; Diakhate L; Thiam D; Mitchell S; Bacterio-Virologie/Universite de Dakar
- [Frequency of HIV virus isolation in the blood and vaginal secretions of seropositive women]
- Int Conf AIDS. 1989 Jun 4-9;5:305 (abstract no. T.B.P.113). Unique Identifier : AIDSLINE ICA5/00146089
- Ly TD; Hoffmeister-Barcellos S; Henrion G; Coulaud JP; Catalan F; Institut Alfred Fournier - Paris
- [Reflections on isolation of HIV in a virology hospital unit]
- Int Conf AIDS. 1989 Jun 4-9;5:306 (abstract no. T.B.P.115). Unique Identifier : AIDSLINE ICA5/00146289
- Fleury HJ; Delord B; Masquelier B; Laboratoire de Virologie, CHR de Bordeaux et Universite de; Bordeaux II, Bordeaux, France
- [Evaluation of a test of rapid detection for HIV-1 and HIV-2 seropositive subjects]
- Int Conf AIDS. 1989 Jun 4-9;5:306 (abstract no. T.B.P.120). Unique Identifier : AIDSLINE ICA5/00146789
- Catalan F; Milovanovic A; Ly TD; Institut Alfred Fournier - Paris
- Longitudinal evaluation of immunologic and viral markers of HIV infection in children: clinical correlation.
- Int Conf AIDS. 1989 Jun 4-9;5:315 (abstract no. T.B.P.172). Unique Identifier : AIDSLINE ICA5/00151889
- Hernandez-Sampelayo T; Perez Alvarez L; Gurbindo MD; Munoz L; Fermosel J; Casado C; Instituto de Salud Carlos III: Unidad de SIDA, Madrid, Spain
- OBJECTIVE: To determine the proportion of HIV infected newborn to HIV Ab+newborn and define changes of immunologic and viral markers that correlate with disease stage, to determine predictive prognostic markers of HIV infection in children. METHODS: We studied 35 HIV+ children born to HIV+ drug abuser mothers, ELISA(E
- [Severe and early neurologic expression in a newborn infected with HIV virus]
- Int Conf AIDS. 1989 Jun 4-9;5:318 (abstract no. T.B.P.187). Unique Identifier : AIDSLINE ICA5/00153389
- Tricoire J; Rolland M; Robert A; Delisle MB; Puel J; Berrebi A; P-ediatrie B, CHU Purpan, 31059 Toulouse C-edex, France
- [Predictive value of clinical and biological status of HIV mothers on their infants' status]
- Int Conf AIDS. 1989 Jun 4-9;5:319 (abstract no. T.B.P.195). Unique Identifier : AIDSLINE ICA5/00154189
- Matheron S; Di Maria H; Courpotin C; Brun-Vezinet F; Dormont D; Balloul H; Hopital Bichat, Paris, France
- Cryptosporidium SP and Isospora belli infections in pediatric patients.
- Unique Identifier : AIDSLINE ICA5/00154289
- De Paula MD; Queiroz W; Janini M; Soraggi C; Hughes V; Rodriguez C; Hospital Emilio Ribas, Sao Paulo, Brazil
- OBJECTIVE: It is known that Isospora belli and Cryptosporidium sp are protozoa very frequently associated with acute self limited diarrheal illness in children and young adults. This evolution is not observed among immunocompromised individuals. This report shows the prevalence of Cryptosporidiosis and Isosporiasis in
- Natural history of AIDS in children of African origin seen in Belgium: evidence for two patterns.
- Int Conf AIDS. 1989 Jun 4-9;5:319 (abstract no. T.B.P.197). Unique Identifier : AIDSLINE ICA5/00154389
- Jonckheer T; Levy J; Alimenti A; Francois A; Ninane J; Institute of Tropical Medicine, Antwerp, Belgium
- OBJECTIVE: To describe the diseases indicative of AIDS in children of African origin seen in Belgium . METHODS: The children of African origin with at least one disease indicative of AIDS according to the latest CDC-case definition were selected. RESULTS: Forty-four children met th
- Perinatal transmission of HIV-1: is a decreased CD4 cell count predictive?
- Int Conf AIDS. 1989 Jun 4-9;5:320 (abstract no. T.B.P.198). Unique Identifier : AIDSLINE ICA5/00154489
- Dattel BJ; Hauer LB; Wofsy CB; Crombleholme W; Weintrub P; Wara D; Sweet RL; University of California, San Francisco, San Francisco General; Hospital, USA
- OBJECTIVE: To investigate possible immunologic, virologic and/or clinical factors which might correlate with perinatal transmission of HIV-1. METHODS: Pregnant HIV+ women were followed prenatally and postpartum with testing for immune function, HIV-1 in peripheral blood, and P24 Antigen (Ag). Infants were considered i
- Pulmonary infectious complications in pediatric AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:320 (abstract no. T.B.P.199). Unique Identifier : AIDSLINE ICA5/00154589
- De Paula MD; Janini M; Queiroz W; Hughes V; Rodriguez C; Loren:co R; Hospital Emilio Ribas, Sao Paulo, Brazil
- OBJECTIVE: Infectious pulmonary processes are very common among HIV infected children. This report shows the etiologic agents more frequently associated with pulmonary disease among our children. METHODS: From January/86 up to November/88, 42 children aged from 2 months to 10 years were followed monthly. All of them f
- Perinatal and heterosexual transmission through HIV-positive women.
- Int Conf AIDS. 1989 Jun 4-9;5:320 (abstract no. T.B.P.200). Unique Identifier : AIDSLINE ICA5/00154689
- Rehmet S; Staszewski S; Wegerich B; Kreuz W; Stille W; Zentrum der Inneren Medizin, Universitatsklinik Frankfurt, FRG
- Since 1984, we have examined HIV-infected women and their partners in order to gain information on infectivity, perinatal and heterosexual transmission rates, and possible relations between these factors. 44 women examined in this period had borne a total of 47 children since their HIV infection. 10 children are posit
- Immunological, serological and clinical evaluation of HIV pos. pregnant women in relation to vertical transmission of HIV.
- Int Conf AIDS. 1989 Jun 4-9;5:320 (abstract no. T.B.P.201). Unique Identifier : AIDSLINE ICA5/00154789
- Muggiasca ML; Conti M; Zanchetta N; Salvaggio L; Novati R; Massironi E; VII dep. Obste. Gynecol., University of Milan. Milan, Italy
- OBJECTIVE: To evaluate the prevalence of vertical transmission of HIV in relation to immunity, HIV related diseases and viral replication in their mothers. METHODS: 23 HIV pos. pregnant women (6 IVDA; 13 ex-IVDA; 3 partners of HIV) have been clinically evaluated and tested for HIV circulating antigen (p24 Ag, Elisa, A
- Clinical and serologic prospective study in infants born from HIV seropositive mothers.
- Int Conf AIDS. 1989 Jun 4-9;5:320 (abstract no. T.B.P.202). Unique Identifier : AIDSLINE ICA5/00154889
- Fortuny C; Sanchez C; Barrera JM; Ercilla MG; Navio D; Jimenez R; Gelabert A; Dept. Pediatry and Blood Transmitted Diseases Unit. Hospital; Clinic. Villarroel 170. Barcelona. Spain
- OBJECTIVE: To evaluate the serological and clinical evolution of newborns (NB) from seropositive mothers. METHODS: 70 NB were clinically controlled monthly and serologically (HIV-Ab, HIV-Ag) each two months. RESULTS: At birth all NB showed IgG Ab against HIV-1 with a mirror pattern in Western blot (WB) when compared w
- Ophthalmic manifestations of HIV infection in an African pediatric population.
- Int Conf AIDS. 1989 Jun 4-9;5:321 (abstract no. T.B.P.203). Unique Identifier : AIDSLINE ICA5/00154989
- Kestelyn P; Lepage P; Stevens AM; Van de Perre P; Department of Ophthalmology and Department of Pediatrics, Centre; Hospitalier de Kigali, National AIDS program, Kigali, Rwanda,; Africa
- OBJECTIVE: HIV infection in adults is associated with a wide variety of ophthalmic manifestations. The purpose of this study was to investigate the spectrum of ophthalmic involvement in a pediatric HIV seropositive population. METHODS: All seropositive children attending the department of pediatrics of the Centre Hosp
- Anthropocentric measures in a cohort of children born to HIV women in Kinshasa, Zaire.
- Int Conf AIDS. 1989 Jun 4-9;5:321 (abstract no. T.B.P.204). Unique Identifier : AIDSLINE ICA5/00155089
- Hassig SE; Manzila T; Nsa W; Kashamuka M; Ryder R; Projet SIDA, Kinshasa, Zaire; Tulane University, New Orleans, USA
- OBJECTIVES: To determine the prevalence and correlates of wasting and stunting in a cohort of children born to HIV+ women. METHODS: Monthly weights, heights and illness experience (diarrhea, pneumonia, fever) were collected on 366 children born to HIV+ women and 513 children born to HIV- women. Weight-for-height (wast
- High HIV-associated infant mortality correlates with poor post-partum maternal health: 18 months follow-up of 477 children (CH) born to HIV(+) mothers (MO) in Zaire.
- Int Conf AIDS. 1989 Jun 4-9;5:321 (abstract no. T.B.P.205). Unique Identifier : AIDSLINE ICA5/00155189
- Badi N; Ryder R; Nsuami M; Matela B; Nsa W; Projet SIDA, Kinshasa, Zaire
- OBJECTIVES: To determine mortality/1000 live births and associated postpartum maternal risk factors in CH with perinatally-acquired HIV infection (PI). METHODS: Infant cause of death and maternal factors predictive of PI and infant mortality were prospectively determined during the 18 month postpartum period in 3 grou
- Perinatal immune function in offspring of HIV seronegative women at risk for AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:321 (abstract no. T.B.P.206). Unique Identifier : AIDSLINE ICA5/00155289
- Rich K; Landay A; Chasnoff I; University of Illinois, Chicago, IL, USA
- OBJECTIVE: To examine possible association of maternal immune function on the immunologic function of infants less than or equal to 6 weeks old. METHODS: Substance abusing women at risk for HIV infection and their infants less than or equal to 6 wks. old were tested for their immune function. Patients were excluded if
- ADCC in HIV-1 infected children.
- Int Conf AIDS. 1989 Jun 4-9;5:321 (abstract no. T.B.P.207). Unique Identifier : AIDSLINE ICA5/00155389
- Walter E; McKinney R; Wilfert C; Tyler D; Bolognesi D; Weinhold K; Duke University Medical Center, Durham, NC, USA
- OBJECTIVE: To determine the prevalence of antibodies directing gp120 specific antibody-dependent cellular cytotoxicity (ADCC) within a cohort of HIV-1 infected children. METHODS: Sera from 35 HIV-1 infected and 10 seronegative children (ages 1 mos-13 yrs) were evaluated for ADCC directing activities in a series of 6-h
- Longterm follow-up of immunologic parameters in HIV-exposed infants.
- Int Conf AIDS. 1989 Jun 4-9;5:321 (abstract no. T.B.P.208). Unique Identifier : AIDSLINE ICA5/00155489
- Wintergerst; Rosendahl WR; Lutz R; Fahrenheim E; Belohradsky BH; immundefekt-Ambulanz der Universitats-Kinderkliniken,; Lindwurmstr.4, 8000 Munchen 2, West-Germany
- INTRODUCTION: Infants with ARC or AIDS following vertically acquired HIV-infection develop severe B- and T-cell defects. The longterm follow-up of immunologic parameters was studied in vertically HIV-infected versus HIV-exposed infants, who became HIV-Ab negative and were otherwise healthy. METHODS: Since 1985 35 chil
- HIV-specific immune responses in congenital HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:321 (abstract no. T.B.P.209). Unique Identifier : AIDSLINE ICA5/00155589
- Luzuriaga K; Koup R; Panicali D; Sullivan J; University of Massachusetts Medical School, Worcester,; Massachusetts, USA
- OBJECTIVE: To investigate HIV-specific immune responses in infants and children with congenital HIV infection. METHODS: Diagnosis of HIV infection was made in 7 children by viral isolation. HIV-specific antibody-dependent cell-mediated cytotoxicity (ADCC) was studied in all of the children using an EBV-transformed lym
- HIV infection in infants: natural history and outcome.
- Int Conf AIDS. 1989 Jun 4-9;5:322 (abstract no. T.B.P.210). Unique Identifier : AIDSLINE ICA5/00155689
- Johnson JP; Nair P; Advani M; O'Neil K; Seiden S; Hines S; University of Maryland School of Medicine, Baltimore, Maryland,; USA
- OBJECTIVE: To determine the natural history and outcome of HIV infection in infants. METHODS: 35 children born to seropositive women were followed from birth to 18 months. Physical exam and laboratory data were collected at 2,4,6,9 and 12 months of age. Nine of these children were confirmed infected by increasing IgG
- Perinatal transmission of HIV - indicators of infection.
- Int Conf AIDS. 1989 Jun 4-9;5:322 (abstract no. T.B.P.211). Unique Identifier : AIDSLINE ICA5/00155789
- Mok J; Hague RA; Hargreaves FD; Whitelaw J; Yap PL; City Hospital, Edinburgh, HIV Immunology Lab, Western General; Hospital, Edinburgh, United Kingdom
- OBJECTIVE: To define the natural history of vertically acquired HIV infection and to elicit methods for early diagnosis. METHODS: Forty nine index infants born to HIV seropositive mothers have been followed up for a median duration of 27 months, together with 24 control infants of HIV seronegative mothers. RESULTS: Cl
- Serum interleukin 2 receptor (sIL-2R) levels in neonates born of HIV-infected mothers: preliminary results.
- Int Conf AIDS. 1989 Jun 4-9;5:322 (abstract no. T.B.P.212). Unique Identifier : AIDSLINE ICA5/00155889
- Ridolfo AL; Galli M; d'Arminio MA; Cocchi F; Novati R; Marchisio P; Massironi P; Balotta C; Infectious Diseases Clinic; University of Milan, Italy
- OBJECTIVE: To state whether sIL-2R levels present any difference between infected and non-infected neonates. METHODS: sIL-2R serum samples were quantified using an ELISA method (T Cell Science) in the 7th and 14th month in 13 neonates born of anti-HIV positive mothers. IgG anti-HIV (ELISA, Abbott; Western Blot, WB-DuP
- Serum neutrophil antibodies in children with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:322 (abstract no. T.B.P.213). Unique Identifier : AIDSLINE ICA5/00155989
- Church JA; Beyer L; Coates T; Childrens Hospital of Los Angeles, and U.S.C. School of Medicine,; Los Angeles, California, USA
- OBJECTIVE: To determine the prevalence of serum neutrophil antibodies (NA) in children with HIV infection and the relationship of NA to neutropenia in these patients. METHODS: Serum was obtained from 18 HIV-infected children, 9M, 9F, 1 to 7 years of age (mean 3.5 +/- 1.5). 3 were asymptomatic (P-1), 6 had ARC (P-2A,F)
- Immunological abnormalities in HIV infection by vertical transmission.
- Int Conf AIDS. 1989 Jun 4-9;5:322 (abstract no. T.B.P.214). Unique Identifier : AIDSLINE ICA5/00156089
- Espanol T; Curell N; Figuera T; Quer J; Garcia X; Caragol I; Immunology and Pediatric Infectious Diseases Units. R.S. Valle; Hebron. Barcelona. Spain
- The first risk for AIDS in Spain is drug addiction and the number of cases by vertical transmission is 2,6% of the total. Immunological abnormalities are very severe in children infected during pregnancy or perinatally, and early diagnosis is important to establish therapeutic proto
- Immunoglobulin E (IgE) in children with acquired immunodeficiency syndrome (AIDS).
- Int Conf AIDS. 1989 Jun 4-9;5:322 (abstract no. T.B.P.215). Unique Identifier : AIDSLINE ICA5/00156189
- Gurbindo Gutierrez MD; Tornero P; del Moral A; Fermosel J; Hernandez-Sampelayo T; Hospital General Grerorio Maranon. Madrid. Spain
- Serum IgE levels are increased in some congenital T-Cell deficiencies and autoimmune disorders. IgE synthesis is regulated by cooperation between T helper and B cells. Patients infected by Human Immunodeficiency Virus (HIV) show an early increase in serum IgG and IgA, indicating and B-cell polyclonal activation. To de
- Early detection of HIV in childhood.
- Int Conf AIDS. 1989 Jun 4-9;5:323 (abstract no. T.B.P.216). Unique Identifier : AIDSLINE ICA5/00156289
- Castillo I; Ruiz-Moreno M; Onenaca F; Varas F; Zanora L; Carreno V; Hepatology Unit, S. Hospital, Madrid, Spain
- It is unclear the fiability of the anti-HIV detection in children from HIV seropositive mothers, as the maternal antibodies and the p24 antigen (HIVAg) remain in children for a mean time of 9-10 months. For this it is necessary to develop new diagnostic techniques for the early identification of the current HIV infect
- Detection of specific IgM antibody by radioimmunoprecipitation assay for early diagnosis of HIV infection in infants.
- Int Conf AIDS. 1989 Jun 4-9;5:323 (abstract no. T.B.P.217). Unique Identifier : AIDSLINE ICA5/00156389
- Fauvel M; Lecomte J; Claessens C; Samson J; Lapointe N; Laboratoire de sante publique du Quebec, Montreal, Canada
- OBJECTIVE: To evaluate IgM-specific HIV antibody (Ab) by radioimmunoprecipitation assay (RIPA) in infants born to seropositive mothers as a tool for early diagnosis. METHODS: Sequential sera from 5 HIV-infected infants were analyzed by standard RIPA with protein-A Sepharose and by RIPA-IgM. For the latter, CNBr-activa
- IgG subclass concentrations and antibody levels to bacterial toxoids in children with human deficiency virus (HIV).
- Int Conf AIDS. 1989 Jun 4-9;5:323 (abstract no. T.B.P.218). Unique Identifier : AIDSLINE ICA5/00156489
- Kreuz W; Enenkel S; Zlelen S; Gungor T; Haas S; Wegerich B; Bauscher P; Ahrens P; Rehmet S; Hofmann D; et al; Klinikum der JW Goethe-Universitat Frankfurt (Main) FRG
- Infection with HIV leads to a combined Immunodefect. As a result of polyclonal B-cell activation there is a significant increase in the serum immunoglobulin levels. The specific humoral immune response is, however, usually impaired. We have investigated to what extent the levels of IgG subclasses undergo change as a r
- [Quantitative Western blot: surveillance of HIV seropositive newborns]
- Int Conf AIDS. 1989 Jun 4-9;5:323 (abstract no. T.B.P.219). Unique Identifier : AIDSLINE ICA5/00156589
- Schiavini D; Puel J; Rousseau A; Gayet-Mengelle C; Laboratoire de Virologie, CHU Purpan, Toulouse, France
- Serologic response to HIV infection in infants.
- Int Conf AIDS. 1989 Jun 4-9;5:323 (abstract no. T.B.P.220). Unique Identifier : AIDSLINE ICA5/00156689
- Johnson JP; Davis E; Shinaberry R; Nair P; University of Maryland School of Medicine, Baltimore, Md, USA
- OBJECTIVE: To document the antibody response to HIV infection in neonates. METHODS: Blood was collected from 35 children born to seropositive women at 2,4,6, and 12 months. Serum was assayed using the DuPont HIV ELISA and P24 assay. IgG and IgM Western blots were run using strips from Organon-Technica and sequential a
- The use of anti-HIV IgM immunoblot in the diagnosis of neonatal HIV infection: a report of 5 cases.
- Int Conf AIDS. 1989 Jun 4-9;5:323 (abstract no. T.B.P.221). Unique Identifier : AIDSLINE ICA5/00156789
- Panmoung W; Sirivichayakul S; Chumdermpadetsuk S; Likitnukul S; Phanuphak P; Chulalongkorn University Hospital, Bangkok, Thailand
- OBJECTIVE: To evaluate the reliability of anti-HIV IgM immunoblot in the early diagnosis of HIV infection in babies of HIV-infected mothers. METHODS: Paired maternal and cord blood from 5 babies at Chulalongkorn University Hospital from HIV-infected intravenous heroin abusing mothers were studied. Anti-HIV IgM immunob
- Is the IgM antibodies status a useful marker to assess the neonates contamination by HIV-1?
- Int Conf AIDS. 1989 Jun 4-9;5:324 (abstract no. T.B.P.222). Unique Identifier : AIDSLINE ICA5/00156889
- Gayet-Mengelle C; Puel J; Tricoire J; Rousseau A; Laboratoire de Virologie, CHU Purpan, Toulouse, France
- OBJECTIVE: Realization of an early diagnosis of congenital or neonatal transmission in order to initiate an immediate therapy against HIV-1. METHODS: We tested IgM antibodies in 53 neonates born to intravenous drug abusers (N=45) heterosexually contaminated (N=7) and unknown mothers (N=1) using the Western-blot assay
- Enumeration of peripheral blood antibody-secreting cells as a diagnostic aid for HIV infection in children.
- Int Conf AIDS. 1989 Jun 4-9;5:324 (abstract no. T.B.P.223). Unique Identifier : AIDSLINE ICA5/00156989
- Nahmias A; Lee F; Nesheim S; O'Neil C; Muther J; Slade B; Depts. of Pediatrics and Pathology, Emory University, Atlanta,; GA, USA
- OBJECTIVE: To evaluate the enzyme-linked immunoblot (ELISPOT) for diagnosis of HIV infection in symptomatic children and infants born to seropos. mothers. METHODS: The ELISPOT, using a gP41 recombinant protein, was applied to peripheral blood mononuclear cells (PBMC) obtained from 31 negative children, 28 children wit
- Recovery of HIV from lymphocytes and monocytes of symptomatic HIV infected children.
- Int Conf AIDS. 1989 Jun 4-9;5:324 (abstract no. T.B.P.224). Unique Identifier : AIDSLINE ICA5/00157089
- Landay AL; Chadwick EG; Kucik S; Yogev R; Rush Medical Center, Chicago, IL, USA
- OBJECTIVE: Correlation of immunologic and virologic findings with clinical status in perinatally HIV-infected children. METHODS: HIV antibody (Ab+) and antigen (Ag+) status was determined by commercial EIA procedures. CD4 and CD8 lymphocyte analysis was performed by a whole blood lysis procedure and analyzed by dual p
- Neopterin - potential early marker of perinatal HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:324 (abstract no. T.B.P.225). Unique Identifier : AIDSLINE ICA5/00157189
- Lischner HW; Bagasra O; Raphael SA; Treston CS; Shandilya L; Temple Univ & St Christopher's Hosp for Children, Philadelphia,; PA, USA
- OBJECTIVE: To test the hypothesis that neopterin (N) levels can differentiate infected from non-infected infants and children of HIV-infected mothers. METHODS: N was determined by 125I radioimmunoassay (DRG, Berlin) in 58 serum and/or EDTA plasma specimens from 40 children of HIV-infected mothers 1 to 59 mo of AGE AND
- High prevalence of HIV-specific IgA and IgG-specific IgM antibodies in neonates of HIV-positive mothers.
- Int Conf AIDS. 1989 Jun 4-9;5:324 (abstract no. T.B.P.226). Unique Identifier : AIDSLINE ICA5/00157289
- Schupbach J; Wunderli W; Kind C; Kernen R; Baumgartner A; Tomasik Z; Swiss National Center for Retroviruses, Institute of Immunology; and Virology, University of Zurich, Zurich, Switzerland
- OBJECTIVE: To analyze the specificity of Western blot (WB)-reactive IgM and IgA in cord bloods. METHODS: Cord blood of 21 babies of HIV+ mothers was tested for HIV-specific IgM or IgA by WB. Preabsorptions of IgG with immobilized protein A or G were done to determine whether reactions were mediated by HIV-specific IgM
- Prospective study of polymerase chain reaction for early detection of HIV infection in infants born to HIV antibody positive women.
- Int Conf AIDS. 1989 Jun 4-9;5:324 (abstract no. T.B.P.227). Unique Identifier : AIDSLINE ICA5/00157389
- Weintrub P; Ulrich P; Edwards J; Rumsey C; Vyas G; Cowan M; University of California, San Francisco, California, USA
- OBJECTIVE: To determine the applicability of polymerase chain reaction (PCR) for early diagnosis of HIV infection in high-risk infants. METHODS: All infants referred for prospective evaluation who were less than or equal to 3 months of age and born to HIV antibody positive women were studied. For PCR, amplifications u
- HIV p24 antigen assay as a diagnostic/prognostic test in pediatric HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:325 (abstract no. T.B.P.228). Unique Identifier : AIDSLINE ICA5/00157489
- Silva TJ; Olson B; Simpson BJ; Andiman WA; Yale University School of Medicine, New Haven, CT, USA
- OBJECTIVE: To learn if HIV p24 antigen (Ag) detection tests can be used to diagnose infection in children or to select mothers at risk of transmitting infection. METHODS: We examined sera from a group of children born to HIV seropositive (HIV+) women as part of an ongoing prospective study of pediatric AIDS. We used a
- Sequential in parallel study of HIV infected mothers and their children since the neonatal period age.
- Int Conf AIDS. 1989 Jun 4-9;5:325 (abstract no. T.B.P.229). Unique Identifier : AIDSLINE ICA5/00157589
- Perez Alvarez L; Gurbindo MD; Munoz L; Hernandez-Sampelayo T; Varela JM; Garcia A; Instituto de Salud Carlos III; Unidad de SIDA. Madrid. Spain
- OBJECTIVES: Sequential follow up of HIV antibodies in mother-child pairs since birth and the analysis of the evolution of the bands against the different viral proteins by WB technique. - Study of the potential usefulness of the P-24 Ag analysis as suggestive marker of neonatal infection. - Confirm the existence of HI
- Comparison of the ortho HIV recombinant antigen neutralization assay and Dupont Western blot for confirmation of ELISA reactive sera from children.
- Int Conf AIDS. 1989 Jun 4-9;5:325 (abstract no. T.B.P.230). Unique Identifier : AIDSLINE ICA5/00157689
- Frost A; Mohla C; Luban N; Campos J; George Washington University Hospital, Washington, DC, USA
- OBJECTIVE: To compare the performance of the HIV Recombinant Antigen Neutralization Assay (RANA) (Ortho Diagnostic Systems, Raritan, NJ, USA) and the HIV Western blot Kit (WB) (DuPont Company, Wilmington, DE, USA) as confirmatory tests of HIV ELISA repeatedly reactive sera from high-risk children. METHODS: RANA uses a
- A novel HIV 1 EIA detects IgG and IgM antibodies in adults and neonates.
- Int Conf AIDS. 1989 Jun 4-9;5:325 (abstract no. T.B.P.231). Unique Identifier : AIDSLINE ICA5/00157789
- Baccard-Longere M; Blanc S; Genoulaz O; Giroud M; Seigneurin JM; Department of virology, A. Michallon Hospital, BP217 X, 38043; Grenoble Cedex, France
- OBJECTIVE: To study the utility of the Wellcozyme HIV Recombinant EIA in HIV diagnosis, and in particular its ability to detect IgM antibodies in infants. METHODS: The EIA was initially evaluated on 4000 sera and 500 positive samples, including 12 sera from individuals at the beginning of sero-conversion. IgM antibodi
- IgM may be directed to conformational epitopes early in seroconversion to HIV.
- Int Conf AIDS. 1989 Jun 4-9;5:325 (abstract no. T.B.P.232). Unique Identifier : AIDSLINE ICA5/00157889
- Gregg R; Smith G; Mayner R; Pollock L; Epstein JS; FDA, Bethesda, MD, USA
- OBJECTIVE: To determine if the apparent insensitivity of a whole virus immunoblot (WB) to early anti-HIV IgM in seroconversion series is a function of conformation or mass of epitopes available in that format. METHODS: Anti-HIV detection by WB (DuPont) and a recombinant gp160, p24 immunoblot (rBlot) were compared usin
- Hypergammaglobulinemia and hypogammaglobulinemia as manifestations of HIV disease in perinatally infected children.
- Int Conf AIDS. 1989 Jun 4-9;5:325 (abstract no. T.B.P.233). Unique Identifier : AIDSLINE ICA5/00157989
- Calvelli T; Steinhauer E; Pathak R; Davydov V; Bernstein L; Rubinstein A; Albert Einstein College of Medicine, Bronx, New York, USA
- OBJECTIVE: Diagnosis of HIV infection in children born to HIV positive mothers can be complicated as a result of infant B cell dysfunction even after disappearance of maternal antibody. In our experience, 8% of children presenting with symptomatology consistent with HIV infection show negative or equivocal ELISAs and
- Association between plasma human immunodeficiency virus type (HIV) viremia and clinical class of pediatric HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:326 (abstract no. T.B.P.234). Unique Identifier : AIDSLINE ICA5/00158089
- Burchett S; Coombs R; Chaloupka K; Stamateou J; Wilson C; Corey L; University of Washington, Seattle, WA, USA
- OBJECTIVE: To develop sensitive virologic markers predictive of asymptomatic and symptomatic pediatric HIV infection. METHODS: Sequentially obtained samples from 12 HIV infected children as they progressed from CDC classification P1 to P2 and from 15 PO children were analyzed. Plasma or peripheral blood mononuclear ce
- Detection of HIV sequences in children born to seropositive mothers.
- Int Conf AIDS. 1989 Jun 4-9;5:326 (abstract no. T.B.P.235). Unique Identifier : AIDSLINE ICA5/00158189
- Borghi V; Selleri L; Lami G; Frigieri G; De Rienzo B; Torelli G; Department of Infectious Diseases, University of Modena, Modena,; Italy
- Purpose: Early detection of HIV infection in children born to seropositive mothers is now possible utilizing the polymerase chain reaction (PCR). METHODS: PCR was performed on DNA extracted from PBMCs of children born to seropositive mothers as described by Saiki. Using the SK 68 - SK 69 primers and the SK 70 probe, h
- Lymphokine and immunoglobulin production in vitro in neonates and infants with human immunodeficiency virus (HIV) infection.
- Int Conf AIDS. 1989 Jun 4-9;5:326 (abstract no. T.B.P.236). Unique Identifier : AIDSLINE ICA5/00158289
- Prieto C; Hanson IC; Hansen TN; Shearer WT; Baylor College of Medicine, Texas Children's Hospital, Houston,; TX, USA
- OBJECTIVE: To assess early immune parameters in HIV+ neonates and infants. METHODS: Interleukin-2 ( IL-2 ) was measured using an IL-2 dependent cell line (CTLL) after stimulation with PHA and augmentation with recombinant IL-2 in placental (Con 1) and infant (Con 2) cont
- Early detection of HIV-1 seroconversion in infants of seropositive mothers using serial dilutions in Western blotting.
- Int Conf AIDS. 1989 Jun 4-9;5:326 (abstract no. T.B.P.237). Unique Identifier : AIDSLINE ICA5/00158389
- Barnes S; Alexander S; Young M; Olopoenia L; Manak M; Frederick W; Howard University Hospital, Washington, DC, USA
- OBJECTIVE: To determine if serial dilutions in Western blot (WB) assay can distinguish HIV-1 seroconversion from passively transferred maternal antibody (Ab) in infants born to seropositive mothers. METHODS: Sequential serum samples collected at 3-month intervals on 17 male and 9 female infants were tested by standard
- Detection of secretory antibodies to HIV in neonates.
- Int Conf AIDS. 1989 Jun 4-9;5:326 (abstract no. T.B.P.238). Unique Identifier : AIDSLINE ICA5/00158489
- Archibald D; Nair P; Hines S; Davis E; Johnson J; University of Maryland at Baltimore, Baltimore, MD, USA
- Viral-specific, non-maternally derived secretory IgA (sIgA) antibodies have been demonstrated soon after birth in certain infections. SIgA to HIV antigens has been detected in infected adults. We collected serum and saliva from 21 children (ages 2 to 48 months) born to women at risk for HIV infection to investigate th
- Anemia and hypergammaglobulinemia in infants with perinatal HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:326 (abstract no. T.B.P.239). Unique Identifier : AIDSLINE ICA5/00158589
- Welsh G; Hutton N; Modlin J; Department of Pediatrics, Johns Hopkins University School of; Medicine, Baltimore, Maryland, USA
- OBJECTIVE: To determine whether hematologic abnormalities or hypergammaglobulinemia are early indicators of HIV infection in infants born to HIV infected mothers. METHODS: Complete blood counts and immunoglobulin concentrations were obtained from 20 five to nine month old infants born to HIV infected mothers and who w
- ELISA (E) and Western blot (WB) patterns and a possible marker of seroreversion (SR) in infants born to seropositive (SP) women.
- Int Conf AIDS. 1989 Jun 4-9;5:327 (abstract no. T.B.P.240). Unique Identifier : AIDSLINE ICA5/00158689
- Mendez H; Holman S; Stevens R; Wethers J; Minkoff H; Landesman S; SUNY-HSCB, Brooklyn, NY, USA
- OBJECTIVE: To describe HIV serological responses and to identify predictors of infection or SR in infants born to SP mothers. METHODS: Pre and post-partum maternal sera, and infant sera collected at birth and at 3 months intervals, were frozen and later tested by E (Dupont) and WB (Organon-Teknika) against known contr
- Sequential Western blot patterns in confirmed HIV seropositive infants.
- Int Conf AIDS. 1989 Jun 4-9;5:327 (abstract no. T.B.P.241). Unique Identifier : AIDSLINE ICA5/00158789
- Luban NL; Criss VC; Joseph S; Mohla C; Campos JM; Children's Hospital National Medical Center, George Washington; University School of Medicine, Washington, DC, USA
- OBJECTIVE: To follow Western blot patterns over time in confirmed HIV seropositive infants and compare loss of specific bands with the Centers for Disease Control classification of disease. METHODS: One hundred eighty-five serial serum specimens were collected at approximate 3 month intervals from 37 confirmed seropos
- Evaluation of the Western blot IgM technique specificity.
- Int Conf AIDS. 1989 Jun 4-9;5:327 (abstract no. T.B.P.242). Unique Identifier : AIDSLINE ICA5/00158889
- Gayet-Mengelle C; Rousseau A; Puel J; Laboratoire de Virologie, CHU Purpan, Toulouse, France
- OBJECTIVE: Evaluation of the Western blot IgM technique specificity. METHODS: During the virological screening of seropositive intravenous drug abusers women (N=67) and infants born to seropositive mothers (N=20) we investigated the IgM status by the Western blot assay (Du Pont HTLV-III Western blot IgM). The test was
- Monitoring of HIV antibody profiles by RIPA as a means of diagnosing infection in infants.
- Int Conf AIDS. 1989 Jun 4-9;5:327 (abstract no. T.B.P.243). Unique Identifier : AIDSLINE ICA5/00158989
- Fauvel M; Samson J; Delage G; Boucher M; Lapointe N; Laboratoire de sante publique du Quebec, Montreal, Canada
- OBJECTIVE: In an ongoing prospective study of HIV perinatal infection, radio-immunoprecipitation assay (RIPA) was evaluated for its ability to differentiate de novo synthesis from passively transferred antibody (Ab). RIPA was also compared with virus isolation and HIV antigen (Ag) detection for early diagnosis. METHOD
- Early diagnosis of HIV-infection in children born to seropositive mothers: critical evaluation of new diagnostic approaches.
- Int Conf AIDS. 1989 Jun 4-9;5:327 (abstract no. T.B.P.244). Unique Identifier : AIDSLINE ICA5/00159089
- De Rossi A; Amadori A; Giaquinto C; Del Mistro A; Mammano F; Zacchello F; Chieco-Bianchi L; Institute of Oncology, University of Padova, Padova, Italy
- OBJECTIVE: Develop a protocol for early diagnosis in children born to HIV seropositive mothers. Correlation between diagnostic results and HIV infection status. METHODS: Children born to seropositive mothers were studied at birth and/or in the first months of life for the following parameters: 1) in vitro production o
- [Significance of systematic culturing of HIV in infants born of infected mothers]
- Int Conf AIDS. 1989 Jun 4-9;5:327 (abstract no. T.B.P.245). Unique Identifier : AIDSLINE ICA5/00159189
- Fleury HJ; Delord B; Douard D; Perel Y; Micheau M; Contraires B; Laboratoire de Virologie, CHR de Bordeaux et Universite de; Bordeaux II, Bordeaux, France
- Infusion of anti p24 antibody rich plasma in two children with persistent HIV antigenaemia - a pilot study.
- Int Conf AIDS. 1989 Jun 4-9;5:328 (abstract no. T.B.P.246). Unique Identifier : AIDSLINE ICA5/00159289
- Hague R; Yap Pl; Mok JY; Jackson GG; Hargreaves FD; Coutts NA; City Hospital, Edinburgh, United Kingdom
- OBJECTIVES: To study the clinical and laboratory sequelae of passive immunotherapy with plasma rich in anti p24 antibody on 2 children with persistent HIV core antigenaemia and seronegative for anti p24 antibody. METHODS: Plasma was harvested as previously described (Lancet 1988 ii647-652). The 2 children aged 5 and 4
- Dideoxycytidine (DDC) alone and in combination with AZT for children with symptomatic HIV infection. A phase I evaluation.
- Int Conf AIDS. 1989 Jun 4-9;5:328 (abstract no. T.B.P.247). Unique Identifier : AIDSLINE ICA5/00159389
- Pizzo PA; Einloth M; Butler K; Eddy J; Meer J; Falloon J; Pediatric Branch, National Cancer Institute, Bethesda, MD, USA
- OBJECTIVE: An agent that inhibits HIV replication without bone marrow suppression would be an important addition to the antiretroviral armamentarium. ddC , a dideoxynucleoside, like AZT
- The effects of encephalopathy and AZT treatment on the social and emotional behavior of pediatric AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:328 (abstract no. T.B.P.248). Unique Identifier : AIDSLINE ICA5/00159489
- Moss H; Wolters P; Eddy J; Weiner J; Pizzo L; Brouwers P; Pediatric Branch, National Cancer Institute, NIH, Bethesda, MD,; USA
- Estimates are that encephalopathy occurs in as many as 80% of pediatric AIDS patients. Evidence of improved CNS functions appears to be a sensitive indicator of the efficacy of pharmacological treatment. Therefore, it is important to further develop objective and systematic methods for monitoring behaviors reflective
- Elevated hepatic transaminases are not associated with increased Zidovudine toxicity in children with congenitally acquired HIV-1 infection.
- Int Conf AIDS. 1989 Jun 4-9;5:328 (abstract no. T.B.P.249). Unique Identifier : AIDSLINE ICA5/00159589
- Martin SR; LeMay MD; McIntosh K; Winter HS; Children's Hospital, Harvard University, Boston, MA, USA
- Zidovudine ( AZT ) has been implicated as the cause of acute hepatitis in some adults with HIV-1 infection. In addition, hepatic dysfunction may potentiate AZT bone-marrow toxicity by altering the metabolism of the drug. Children with elevated transamin
- Long-term treatment of symptomatic HIV-infection in children with Zidovudine.
- Int Conf AIDS. 1989 Jun 4-9;5:328 (abstract no. T.B.P.250). Unique Identifier : AIDSLINE ICA5/00159689
- Vocks M; Wintergerst U; Sauer S; Kreuz W; Wahn V; Rosendahl C; Koch S; Haas S; Debatin KM; Kynast I; et al; Dept. of Pediatrics, Univ. Berlin, FRG
- OBJECTIVE: To evaluate clinical, immunological and virological effects of long-term therapy in children with Zidovudine (ZDV). METHODS: 24 patients (pts) with AIDS ranging in age from 1-20 years have been treated with ZDV orally in a dosage of 3.5 mg/kg (12 pts) every 6 hours for meanly 44 weeks (4 pts 5 mg/kg; 2 pts
- Chorioretinitis responding to AZT therapy in an infant with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:328 (abstract no. T.B.P.251). Unique Identifier : AIDSLINE ICA5/00159789
- Jonckheer T; Pierre C; de Seliys A; Moens E; Taelman H; Piot P; Institute of Tropical Medicine, Antwerp, Belgium
- INTRODUCTION: Cytomegalovirus ( CMV ) chorioretinitis is exceptionally reported in children with AIDS (2 cases mentioned). In adults CMV chorioretinitis is known to respond only to Ganciclovir or Foscarnet therapy. CASE REPORT: A six months old boy of African orig
- AZT therapy in HIV infected children.
- Int Conf AIDS. 1989 Jun 4-9;5:329 (abstract no. T.B.P.252). Unique Identifier : AIDSLINE ICA5/00159889
- Terragna A; De Maria A; Ciravegna B; Loy A; Forni F; Ferrazin A; 1 C1 Mal Infettive Istituto G. Gaslini Genova, Italy
- 12 children (6 males, 6 females) aged 4 months to 12 years, with HIV infection in class P1 (1 case) or P2 (11 cases) (CDC 1987) were treated with Zidovudine (20 to 28 mg/kg/d) every six hours for a mean of six months (range 2-6 months). Out of the study patient 12/12 were HIVp24Ag positive, 7/12 virus culture positive
- Zidovudine treatment in adolescent hemophiliac children with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:329 (abstract no. T.B.P.253). Unique Identifier : AIDSLINE ICA5/00159989
- Knutsen AP; Bouhasin JD; Gioia K; Mueller KB; St. Louis University Medical Center, St. Louis, MO, USA
- Nine hemophilia children with HIV infection, mean age of 13.8-years-old (range 7.6 to 18.1 years), were treated with Zidovudine (azidothymidine; AZT ), dose 115+/-14 mg/M2/dose four times daily orally for 9.9+/-3.6 months. Three children had acquired i
- Disease progression and effect of Zidovudine (AZT) in pediatric AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:329 (abstract no. T.B.P.254). Unique Identifier : AIDSLINE ICA5/00160089
- Gupta A; Ravipati M; Slade H; Leombruno C; Marecki M; Pahwa S; Dept. of Pediatrics, North Shore University Hospital, Cornell; University Medical College, Manhasset, NY, USA
- OBJECTIVE: To evaluate infants and children with presumed or established HIV infection and influence of AZT treatment. METHODS: 46 cases, age range 1 mo. to 8 years at presentation, of whom 32 had P1/P2 disease and 14 were in the PO category were eval
- Our experience in treatment with Zidovudine in children.
- Int Conf AIDS. 1989 Jun 4-9;5:329 (abstract no. T.B.P.255). Unique Identifier : AIDSLINE ICA5/00160189
- Mellado MJ; Cilleruelo MJ; Garcia M; Villota J; Perez ML; Fontelos PM; Instituto Carlos III. Serv. Pediatria. Madrid. Spain
- OBJECTIVE/METHODS: In October 87, we began a prospective study to evaluate the effectiveness of Zidovudine (ZDV) in the treatment of children suffering from AIDS. Selection parameters were: 1) Children with viremia or HIV antibodies and symptomatic infection according to class P2 of CDC for pediatric AIDS. 2) To be ol
- Selenium deficiency and cardiomyopathy in malnourished pediatric AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:329 (abstract no. T.B.P.256). Unique Identifier : AIDSLINE ICA5/00160289
- Kavanaugh-McHugh A; Rowe S; Benjamin Y; Hutton N; Modlin J; Ruff A; The Johns Hopkins Hospital, Baltimore, MD, USA
- OBJECTIVE: To examine the relationship between selenium deficiency and cardiomyopathy in pediatric AIDS patients. METHODS: Echocardiograms and serum selenium values were obtained on 9 pediatric patients undergoing therapy with azidothymidine for symptomatic HIV disease. Cardiomyopathy was defined as ejection fraction
- Clinical and immunological course of HIV-infection in hemophiliac and perinatally infected children prophylactically treated with immunoglobulins containing high titers of anti-CMV, anti-EBV and anti-HIV and timing of azidothymidine indication. A prospective longitudinal study of 61 children.
- Int Conf AIDS. 1989 Jun 4-9;5:329 (abstract no. T.B.P.257). Unique Identifier : AIDSLINE ICA5/00160389
- Kreuz W; Ebener U; Wegerich B; Gungor T; Haas S; Enenkel S; Debatin KM; Rehmet S; Krackhardt B; Kynast I; et al; Klinikum der J.W. Goethe-Universitat, Frankfurt am Main, FRG
- In our clinic we care for 61 children consisting of 10 HIV-infected hemophiliacs or von Willebrand patients (up to 19 years) and 51 born to HIV-positive mothers (up to 6,5 years). 24 children are classified as P 1 and P2, 6 are classified as P O according to CDC-criteria, 31 were initially P O and considered not to be
- Experience with central venous catheters in pediatric AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:330 (abstract no. T.B.P.258). Unique Identifier : AIDSLINE ICA5/00160489
- Futterman D; Connor E; Boland M; Oleske J; Children's Hospital of NJ & UMD-NJ Medical School, Newark, New; Jersey, USA
- OBJECTIVE: Children with AIDS are at high risk for infection and malnutrition, frequently requiring prolonged venous access for antibiotics and nutritional support. We undertook this study to determine the course and complication rate of central venous catheters (Broviacs) when used in a pediatric AIDS population. MET
- Neoplastic diseases in children with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:330 (abstract no. T.B.P.259). Unique Identifier : AIDSLINE ICA5/00160589
- Joshi VV; Connor EM; DiCarlo F; Epstein LG; Oleske JM; Departments of Clinical Pathology and Pediatrics, East Carolina; University School of Medicine, Greenville, NC, USA
- OBJECTIVE: To describe the incidence and types of neoplastic diseases (ND) in children with AIDS. METHODS: Biopsy (35 cases) and/or autopsy (18 cases) material from 102 HIV infected children. RESULTS: Seven cases showed ND. The risk factor in five of the cases was parental IV drug use. In 2 cases HIV was acquired via
- Safety and efficacy of central venous catheters in pediatric AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:330 (abstract no. T.B.P.260). Unique Identifier : AIDSLINE ICA5/00160689
- Gleason-Morgan D; Church J; Bagnall H; Atkinson J; Childrens Hospital of Los Angeles & University of Southern; California School of Medicine, Los Angeles, California, USA
- OBJECTIVE: To determine the safety and efficacy of central venous catheters (CVCs) in pediatric AIDS patients (pts). METHOD: A retrospective chart review of children with CDC-defined AIDS (P2D) who had CVCs placed due to inadequate venous access. RESULTS: The medical records of 11 pts (7 male, 4 female), ages 3 mos to
- HIV infection (HIV) in patients (pts) treated for leukemia or solid tumor, a pediatric oncology group (POG) study.
- Int Conf AIDS. 1989 Jun 4-9;5:330 (abstract no. T.B.P.261). Unique Identifier : AIDSLINE ICA5/00160789
- Baruchel S; Clavel L; Toledano S; McGill University, Montreal, Quebec, Canada
- OBJECTIVE AND METHODS: A questionnaire was sent to POG institutions to enquire about (a) the number of pts infected by HIV among children treated for leukemia or solid tumors; (b) the impact of chemotherapy on the natural history of HIV; (c) the interaction between HIV and cancer; (d) and institutional attitudes regar
- Very late onset of group B streptococcal sepsis in infants with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:330 (abstract no. T.B.P.262). Unique Identifier : AIDSLINE ICA5/00160889
- Di John D; Johnson JP; Lawrence R; Schieken LS; Rennels MB; New York University Medical Center-Bellevue Hospital Center, New; York, NY, USA
- OBJECTIVE: To describe characteristics of Group B streptococcal (GBS) disease in HIV infected children. METHODS: GBS disease was identified in 3/200 (1.5%) of HIV infected children diagnosed at the University of Maryland and NYU Medical Center. Charts were reviewed to describe clinical features, course, and outcome of
- Diarrhea and its consequences in HIV-infected children.
- Int Conf AIDS. 1989 Jun 4-9;5:330 (abstract no. T.B.P.263). Unique Identifier : AIDSLINE ICA5/00160989
- Kotloff K; Johnson JP; Nair P; Losonsky GA; Young A; Morris JG; University of Maryland School of Medicine, Baltimore, Maryland,; USA
- OBJECTIVE: To determine the incidence, etiology, and sequelae of diarrhea in children with symptomatic HIV infection. METHODS: Children with AIDS and ARC (n=16) were prospectively enrolled and serially evaluated. When a physician visit was made for diarrhea, a whole stool or rectal swab was examined for bacterial ente
- Burkitt lymphoma in an HIV-infected child.
- Int Conf AIDS. 1989 Jun 4-9;5:331 (abstract no. T.B.P.264). Unique Identifier : AIDSLINE ICA5/00161089
- Caselli D; Arico M; Deicas A; Michelone G; Maccabruni A; Lanzarini P; Dept. Pediatrics, University of Pavia, Italy
- HIV infection in children is infrequently complicated with malignancies: Kaposi sarcoma (less than 5%), a few cases of malignant brain lymphoma, one case of Burkitt lymphoma (BL) were reported. We describe BL in a 3-year-old white female, born to drug abuser seropositive mother, admitted because of fever, anorexia, in
- Chronic mucocutaneous candidiasis in pediatric AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:331 (abstract no. T.B.P.265). Unique Identifier : AIDSLINE ICA5/00161189
- Iosub S; Bamji M; Stone RK; Gromisch DS; Wasserman E; New York Medical College, New York, USA
- OBJECTIVE: To compare the incidence of persistent mucocutaneous candidiasis in patients diagnosed as AIDS in the first year of life (group I) vs those diagnosed later (group II). METHODS: The study was performed at two public hospitals in New York City on sixty two patients with perinatal HIV infection admitted from 1
- Opportunistic infections and mortality in an urban pediatric population infected with human immunodeficiency virus (HIV).
- Int Conf AIDS. 1989 Jun 4-9;5:331 (abstract no. T.B.P.266). Unique Identifier : AIDSLINE ICA5/00161289
- Hanson IC; Rosenblatt HM; Shearer WT; Baylor College of Medicine and Texas Children's Hospital,; Houston, Texas, USA
- OBJECTIVE: To define opportunistic infections (OI) that were most prevalent and linked with the highest mortality rate in an urban pediatric population. METHODS: 73 pediatric HIV patients followed up to 7 years (mean 2 years) were reviewed for evidence of OI (Centers for Disease Control, stage D-1). RESULTS: As in the
- Spectrum of infections identified at autopsy in pediatric AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:331 (abstract no. T.B.P.267). Unique Identifier : AIDSLINE ICA5/00161389
- Ross LA; Wong VK; Gomperts ED; Ricalde AL; Church JA; Childrens Hospital of Los Angeles and U.S.C. School of Medicine,; Los Angeles, California, USA
- OBJECTIVE: To identify the spectrum and sites of infection in children dying of AIDS. METHOD: 33 children with full-blown AIDS have been followed at Childrens Hospital of Los Angeles; 22 have expired; 12 postmortem examinations revealed the following: TABULAR DATA, SEE ABSTRACT VOLUME. CONCLUSION: Multiple infectious
- Hematologic effects and outcome of Zidovudine (AZT) therapy.
- Int Conf AIDS. 1989 Jun 4-9;5:331 (abstract no. T.B.P.268). Unique Identifier : AIDSLINE ICA5/00161489
- Schlech W; Marrier G; Johnston B; Dalhousie University Faculty of Medicine, Halifax, Nova Scotia,; Canada
- OBJECTIVE: To describe the hematologic effects and outcomes of Zidovudine ( AZT ) therapy in CDC group III and group IV HIV-infected patients (pts). METHODS: 20 AIDS and 14 group IVa and group III (n=34) pts were enrolled in the open trial of AZT and fo
- Thrombocytopenia in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:331 (abstract no. T.B.P.269). Unique Identifier : AIDSLINE ICA5/00161589
- Sacchi G; Zorzi F; Bonetti M; Falchetti M; Stellini R; Scalzini A; 1st Service of Pathology, Spedali Civili Brescia, Italy
- OBJECTIVE: To describe the incidence of thrombocytopenia in HIV positive pts., to assess the bone marrow lesions and the prognostic significance of thrombocytopenia in the AIDS evolution. METHODS: On Dec. 31, 1988, eighty-eight cases of thrombocytopenia were observed within a population of about 1000 HIV positive pts.
- Platelet production in HIV infection - evidence for a compensated thrombolytic state enhanced by AZT.
- Int Conf AIDS. 1989 Jun 4-9;5:332 (abstract no. T.B.P.270). Unique Identifier : AIDSLINE ICA5/00161689
- Ballem P; Belzberg A; Chambers H; Spruston B; Department of Medicine. St. Paul's Hospital, Vancouver, B.C.,; Canada
- Thrombocytopenia (decreased plt) is common in HIV infection, often due to marrow suppression 2 degrees infection, drugs or infiltration. In the absence of these, some patients have decreased plts. associated with increased plt.-associated IgG (HIV-1TP). Kinetic studies performed with 111-Indium-labelled plts. in 12 pa
- Effects of long term Zidovudine on platelet count.
- Int Conf AIDS. 1989 Jun 4-9;5:332 (abstract no. T.B.P.271). Unique Identifier : AIDSLINE ICA5/00161789
- Flegg PJ; Jones ME; MacCallum LR; Williams KG; Cook MK; Brettle RP; ID Unit, City Hospital, Haematology, Edinburgh, United Kingdom
- OBJECTIVE: To assess the long term platelet response of Zidovudine following reports of short term beneficial effects in HIV related immune thrombocytopenia (ITP). METHODS: 38 patients received Zidovudine in standard doses with adjustments or stoppage for toxicity for greater than 12 weeks (14 with AIDS and 24 others)
- Response to splenectomy for severe HIV-related thrombocytopenia in 10 drug abusers and pathological features of the spleens.
- Int Conf AIDS. 1989 Jun 4-9;5:332 (abstract no. T.B.P.272). Unique Identifier : AIDSLINE ICA5/00161889
- Landonio G; de Cataldo F; Gargantini L; Nosari AM; Costantini M; Gambacorta M; Department of Hemathology Niguarda Ca'Granda Hospital, Milan,; Italy
- OBJECTIVE: To evaluate the response to splenectomy for severe HIV-related thrombocytopenia in a medium term follow-up and the pathological features of the spleens. METHODS: 10 patients (all intravenous drug abusers -IVDAs-) with severe HIV-related thrombocytopenia (PLT less than 5x10 (9)/L), who failed to respond to s
- HIV-related immune thrombocytopenia: follow up and treatment of 132 patients.
- Int Conf AIDS. 1989 Jun 4-9;5:332 (abstract no. T.B.P.273). Unique Identifier : AIDSLINE ICA5/00161989
- Oksenhendler E; Archambault MP; Delfraissy JF; Bierling P; Peynet J; SelIgMann M; Groupe d'etude des cytopenies liees au HIV - Paris - France
- OBJECTIVE: Longitudinal study of HIV infected patients with thrombocytopenia (platelets less than 50 x 10(9)/1). Patients at initial evaluation: 132 patients (IV drug addicts: 56; homosexual men: 36, hemophiliacs: 23; others: 17). 56% belonged to CDC group II, 30% to group III and 14% to group IV, none had AIDS. CD4 c
- HIV - associated thrombocytopenia (HTP), platelet - associated immunoglobulin (PAI) and Zidovudine.
- Int Conf AIDS. 1989 Jun 4-9;5:332 (abstract no. T.B.P.274). Unique Identifier : AIDSLINE ICA5/00162089
- Carcaba V; Carton JA; Vicente P; Maradona JA; SanRoman F; Llorente R; Garcia Z; Hospital Universitario de Oviedo. Spain
- OBJECTIVE: To establish the incidence, permanence and pathogenic role of PAI in HTP treated with Zidovudine, and in non-thrombocytopenic HIV-infected patients. METHODS: PAI was determined by platelet suspension immunofluorescence test to 23 HIV-infected patients with normal platelet count and 8 HTP (less than 100 x 10
- Therapy of HIV associated thrombocytopenia.
- Int Conf AIDS. 1989 Jun 4-9;5:332 (abstract no. T.B.P.275). Unique Identifier : AIDSLINE ICA5/00162189
- Lim SG; Lee CA; Kernoff PB; Haemophilia Centre and Haemostasis Unit, Academic department of; Haematology, Royal Free Hospital, London, United Kingdom
- OBJECTIVE: To assess the therapy of HIV associated thrombocytopenia. METHODS: A retrospective analysis of 111 HIV positive haemophiliacs showed 7 with thrombocytopenia less than 50 x 10(9)/L. 4 patients were CDC II, 1 was CDC III and 2 were CDC IV. Their mean age was 26 years (range:5-38), and they had been HIV positi
- Lack of efficacy of on-line column-A-adsorption in treatment of HIV-associated ITP.
- Int Conf AIDS. 1989 Jun 4-9;5:333 (abstract no. T.B.P.276). Unique Identifier : AIDSLINE ICA5/00162289
- Scolaro MJ; Kennedy P; Los Angeles Oncologic Institute, St. Vincent Medical Center, Los; Angeles, California 90057, USA
- OBJECTIVE: To determine the clinical efficacy of on-line CAA in restoring normal platelet count in patients with HIV-related ITP. Previous studies have demonstrated the value of off-line CAA in treatment of HIV-1TP. METHOD: We treated 7 patients with ITP (platelet count range 18,000/cu mm to 85,000/cu mm, mean 39,000/
- [Effectiveness of zidovudine in a low dose in treating thrombopenia related to HIV virus]
- Int Conf AIDS. 1989 Jun 4-9;5:333 (abstract no. T.B.P.277). Unique Identifier : AIDSLINE ICA5/00162389
- Routy JP; Blanc AP; Garabedian C; Maurice C; David M; Jolio Y; Hopital Cezanne 13616 Aix-en-Provence France
- Combined steroid-Zidovudine treatment of severe thrombocytopenia associated with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:333 (abstract no. T.B.P.278). Unique Identifier : AIDSLINE ICA5/00162489
- Arrizabalaga J; Iribarren JA; Santamaria JM; Zubero Z; Garde C; Zulaica D; Hospital Nuestra Senora de Aranzazu, San Sebastian, and; Hospital Civil de Basurto, Bilbao, Spain
- OBJECTIVE: Assessment of the efficacy of combined steroid-Zidovudine treatment in patients with severe thrombocytopenia and HIV infection. METHODS: Since June 1988 a therapeutic protocol of steroids and Zidovudine has been in effect for patients with HIV infection and severe thrombocytopenia (platelets under 20.10(9)/
- Phase II study of alpha 2A interferon (INF) associated with AZT in patients (pts) with AIDS related Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:333 (abstract no. T.B.P.279). Unique Identifier : AIDSLINE ICA5/00162589
- Gonzalez-Canali G; Navarro-Carola E; De Gramont A; Demuynck B; Louvet C; Krulik M; Hopital Saint-Antoine - Paris - France
- INF is the standard therapy for AIDS-KS and AZT has demonstrated antiviral activity in AIDS. 15 pts with AIDS-KS received alpha 2A INF (18 MU daily IM) associated with AZT 1200 mg orally (200 mg every 4 hs) daily. All pts had biopsy proven KS with a m
- Treatment of lymphomas (NHL) associated with human immunodeficiency virus (HIV).
- Int Conf AIDS. 1989 Jun 4-9;5:333 (abstract no. T.B.P.280). Unique Identifier : AIDSLINE ICA5/00162689
- Gisselbrecht C; Oksenhendler E; Farcet JP; Dombret H; Coiffier B; Raphael M; Paris, Creteil, Lyon, Nice, France. Supported by INSERM
- NHL-HIV have a poor prognosis related to both lymphoma and associated opportunistic infections (OI). In order to evaluate the place of intensive chemotherapy in a subset of patients with NHL-HIV. Pts were stratified in 2 risk groups. Group A: no OI and performance status less than 2 (OMS); group B: performance status
- Correlation of effects of interferon-alpha in AIDS-associated Kaposi's sarcoma with serum levels and dose.
- Int Conf AIDS. 1989 Jun 4-9;5:333 (abstract no. T.B.P.281). Unique Identifier : AIDSLINE ICA5/00162789
- Sawyer L; Boone E; Zoon K; Metcalf J; Lane H; Quinnan G; Division of Virology, CBER, FDA, Bethesda, MD, USA
- OBJECTIVE: To study the relationship between the dose and blood levels of interferon-alpha (IFN) to responses to treatment of patients with Kaposi s sarcoma (KS). METHODS: We studied 37 patients with KS enrolled in studies of IFN therapy alone and in combination with Zidovudine (
- Efficacy of high dose (50 MU/M2) intravenous recombinant interferon ALFA-2-b (HD.IV.rIFN alpha 2b) in AIDS related Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:334 (abstract no. T.B.P.282). Unique Identifier : AIDSLINE ICA5/00162889
- Beaucaire G; Chidiac C; Brion JP; Lacut JY; Massip P; Department of Infectious Diseases. University of Lille. France.
- OBJECTIVES: From March 1987 to December 1988, an open study was performed to assess the efficacy of HD.IV.rIFN alpha 2b that was given 5 days/week, every other week, in the treatment of AIDS related Kaposi s sarcoma (AIDS/KS). METHODS: The KS stages were ranged according to the KRIGEL classification with a special ref
- HIV-antigenemia in patients with AIDS-related Kaposi's sarcoma (KS) treated with recombinant alpha-2a interferon (IFN).
- Int Conf AIDS. 1989 Jun 4-9;5:334 (abstract no. T.B.P.283). Unique Identifier : AIDSLINE ICA5/00162989
- Rozenbaum W; Gharakhanian S; Rouzioux C; De Sahb R; Bugard M; Cardon B; Infectious Disease Unit, Rothschild Hosp.; Virology lab, Necker; Hosp.; Paris, France
- OBJECTIVE: To assess the link between HIV antigen (Ag) level and clinical response to IFN in KS. METHODS: 76 males, mean age 37.5, were treated for biopsy-proven KS with 18M units a day of IFN during a mean of 168+/-77 days. Ag was assessed before and during treatment, measured blind by the Abbott technique with conce
- Chemotherapy with or without granulocyte-marcrophage colony stimulating factor (rGM-CSF) in patients with AIDS-associated non-Hodgkin's lymphoma (NHL).
- Int Conf AIDS. 1989 Jun 4-9;5:334 (abstract no. T.B.P.284). Unique Identifier : AIDSLINE ICA5/00163089
- Kaplan LD; Kahn JO; Grossberg H; Volberding PA; Department of Medicine, San Francisco General Hospital, San; Francisco, CA, USA
- OBJECTIVE: To determine whether rGM-CSF can reduce chemotherapy-induced myelosuppression in patients with AIDS-associated NHL. METHODS: Patients were randomized to receive CHOP (Cyclophosphamide 1g/m2/d1, Doxorubicin 40mg/m2/d2, vincristine 2mg, Prednisone 100mg/m2/d1-5) with or without rGM-CSF 10-15mcg/kg subcutaneou
- Adoptive transfer of immunity to recall antigens following allogeneic bone marrow transplantation (BMT) in an AIDS patient with non-hodgkin's lymphoma (NHL).
- Int Conf AIDS. 1989 Jun 4-9;5:334 (abstract no. T.B.P.285). Unique Identifier : AIDSLINE ICA5/00163189
- Donnenberg AD; Holland HK; Burns WH; Santos GW; Saral R; The Johns Hopkins University, Baltimore, MD, USA
- OBJECTIVES: We have previously shown that transfer of donor immunity can be reproducibly achieved after allogeneic BMT by boosting the BM donor before transplant and/or the recipient on the day of BMT. The present study was conducted on a 41 yo HIV-1 culture+ man with NHL who received combined modality therapy of allo
- Carbon monoxide diffusing capacity (DLCO) as a predictor of lung function in patients receiving bleomycin for treatment of Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:334 (abstract no. T.B.P.286). Unique Identifier : AIDSLINE ICA5/00163289
- Akil B; Ireland-Gill A; Espinar BE; Gill P; University of Southern California, Los Angeles, California 90033
- OBJECTIVES: The purpose of this study was to evaluate the effect of Bleomycin-containing chemotherapeutic regimens on the pulmonary function in patients with Kaposi s Sarcoma (KS) associated with AIDS. METHODS: We evaluated 19 patients who had at least two sets of Pulmonary Function Tests (PFT s) one before and after
- Regression of Kaposi's sarcoma (KS) following PROSORBA(R) column treatments.
- Int Conf AIDS. 1989 Jun 4-9;5:334 (abstract no. T.B.P.287). Unique Identifier : AIDSLINE ICA5/00163389
- Reed DE; Snyder HW; Balint JP; Jones FR; IMRE Corporation, Seattle, WA, USA
- OBJECTIVE: - To modulate immune system activity and induce regression of KS by removal of IgG and circulating immune complexes (CIC) from patient plasma. METHODS: - A clinical trial of immunoadsorption of plasma was carried out with 23 patients who had progressive KS and had received no anti-tumor or anti-viral therap
- Adverse reactions with high dose (50MU/M2) intravenous recombinant interferon ALFA 2b (HD.IV.rIFN.alpha 2b) in AIDS related Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:335 (abstract no. T.B.P.288). Unique Identifier : AIDSLINE ICA5/00163489
- Beaucaire G; Mouton Y; Biron F; Lepeu G; Reynes J; Department of Infectious Diseases. University of Lille. France
- OBJECTIVES: From March 1987 to December 1988, an open study was performed to appraise the efficacy and the tolerance of HD.IV.rIFN alpha 2b, that was given 5 days/week, every other week, in the treatment of AIDS related Kaposi s sarcoma (AIDS/KS). METHODS: The 34 initially enrolled patients were all men: 25 homo- and
- High doses of interferon ALFA 2-b in Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:335 (abstract no. T.B.P.289). Unique Identifier : AIDSLINE ICA5/00163589
- Ocana I; De Luis A; Ruiz I; Bejarano E; De Buen L; Martinez Vazquez JM; Department of Internal Medicine, Hospital Vall d'Hebron,; Barcelona, Spain
- OBJECTIVE: The efficacy and safety of Interferon alfa 2-b (Intron A) were evaluated in patients with AIDS related Kaposi s sarcoma (KS). METHODS: From June 1986 to December 1988, 9 patients (8 homosexual or bisexual men and 1 drug-addict woman) were included in this trial. The mean age was 32 years (20-41 Yrs). The KS
- Intralesional vinblastine (Velban) treatment of lesions of Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:335 (abstract no. T.B.P.290). Unique Identifier : AIDSLINE ICA5/00163689
- Conant MA; Galzagorry G; Illeman M; University of California, San Francisco, California, USA
- OBJECTIVE: To determine effectiveness and safety of using Vinblastine (Velban) therapy intralesionally into individual lesions of Kaposi s sarcoma. METHODS: Fifteen subjects with previously diagnosed Kaposi s sarcoma and positive HIV antibody tests were entered into the study. Lesions of Kaposi s sarcoma of any cutane
- Remission of Kaposi-sarcoma by a combined therapy with interferon-beta + AZT in an AIDS patient.
- Int Conf AIDS. 1989 Jun 4-9;5:335 (abstract no. T.B.P.291). Unique Identifier : AIDSLINE ICA5/00163789
- Knechten H; Braeck F; Hem.-Onc. Institute, Aachen, FRG
- We report the case of an HIV-1-infected patient with Kaposi-Sarcoma (KS), who was treated with human fibroblast interferon-beta (IFN-beta, FIBLAFERON(R), Dr. Rentschler, Laupheim, FRG)+ AZT (RETROVIR(R), Wellcome, Burgwedel, FRG). The HIV-1-infection
- Interferon administered intralesionally in skin, conjunctiva and oral cavity lesions in patients with AIDS-related Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:355 (abstract no. T.B.P.292). Unique Identifier : AIDSLINE ICA5/00163889
- Sulis E; Floris C; Sulis ML; Tedde A; Turno R; Contu L; Div. Medicina I, Osp. Oncol. A. Businco, USL 21, Cagliari,; Italy
- The efficacy of interferon (IFN) in the therapy of AIDS related Kaposi s Sarcoma (AIDS-KS) seems to be dose-dependent. The concentration of massive doses of IFN in the tumoral lesions by intralesional injection seems to be a rational approach. We have treated 9 male patients (average age 24 years, heterosexuals, drug
- Assessment of the management of Kaposi's sarcoma (KS) in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:335 (abstract no. T.B.P.293). Unique Identifier : AIDSLINE ICA5/00163989
- Garcia-Polo I; Santos I; del Arco C; Fraga J; Fernandez J; Noguerado A; Hospital de la Princesa,-M. Interna, Universidad Autonoma,; Madrid-Spain
- OBJECTIVES: To assess the usefulness of Zidovudine (ZDV) and Interferon (IF) in patients with KS associated to AIDS. PATIENTS AND METHODS: 17 patients aged 24-44 years (mean 34,3), without previous opportunistic infection with histologically proven KS. 7 patients received ZDV - only (1200 mg/day) and 4 patients with m
- Comparison of ribavirin versus placebo for preventing the progression of HIV infected subjects from CDC stage III to stage IV.
- Int Conf AIDS. 1989 Jun 4-9;5:336 (abstract no. T.B.P.294). Unique Identifier : AIDSLINE ICA5/00164089
- Barcelona, Madrid, Bilbao, San Sebastian, Spain
- OBJECTIVE: To compare the efficacy of ribavirin versus placebo to prevent the progression of HIV-infected patients from CDC stage III to stage IV. METHODS: 131 HIV-infected patients (20% homosexuals, 64% drug addicts) on CDC stage III, and a CD4 cell count between 50 and 500 per mm3 were included in a double blind mul
- Dextran sulfate is poorly absorbed after oral administration.
- Int Conf AIDS. 1989 Jun 4-9;5:336 (abstract no. T.B.P.295). Unique Identifier : AIDSLINE ICA5/00164189
- Lorentsen K; Hendrix C; Collins J; Eckel R; Petty B; Lietman P; Johns Hopkins University, Baltimore, MD
- OBJECTIVE: To determine whether dextran sulfate, a synthetic analogue of heparin with anti-human immunodeficiency virus activity in vitro, is absorbed after oral administration. METHODS: Volunteers were given an 1800 mg. oral dose followed forty-eight hours later by a 225 mg. intravenous infusion of dextran sulfate. B
- Ribavirin dose escalating phase 1 trial in patients with AIDS and ARC.
- Int Conf AIDS. 1989 Jun 4-9;5:336 (abstract no. T.B.P.296). Unique Identifier : AIDSLINE ICA5/00164289
- Crumpacker C; Cotton D; Pearlstein G; Valentine F; Mills J; Spector S; Beth Israel Hospital, Boston, MA, USA
- OBJECTIVE: To carry out an increasing dose phase I trial to find maximum tolerated dose of Ribavirin (RBV). METHODS: Patients in 3 arms, 1) AIDS no previous treatment; 2) ARC; 3) AIDS, AZT failures; were enrolled in a 6 month trial of RBV 800, 1200, 1
- Phase I study of 2', 3' dideoxyinosine (ddI) given once daily to patients with AIDS or ARC.
- Int Conf AIDS. 1989 Jun 4-9;5:336 (abstract no. T.B.P.297). Unique Identifier : AIDSLINE ICA5/00164389
- Cooley T; Saunders CA; Perkins CJ; McCaffery RP; McLaren C; Liebman HA; Boston University School of Medicine, Boston, MA, USA
- OBJECTIVE: To determine maximum tolerated dose (MTD), pharmacokinetics (PK) and efficacy of iv and oral ddI given once daily. METHODS: To date, 8 patients (6 men, 2 women) with AIDS (4) or ARC (4) were treated. Plasma and urine were collected after initial iv infusion and at steady state doses of 0.8 (1), 2 (5), 3.5 (
- Evaluation of megestrol acetate treatment in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:336 (abstract no. T.B.P.298). Unique Identifier : AIDSLINE ICA5/00164489
- Gold J; Oliver C; Albion Street (AIDS) Centre, Sydney Hospital, Sydney, Australia
- OBJECTIVE: To evaluate the components of weight gain associated with megestrol acetate therapy in cachexic males with stage IV HIV disease. METHODS: Ten males with a weight loss of 15-20% of usual weight due to late stage HIV disease were treated with megestrol acetate (80 mg, three times a day). Subjects were treated
- Recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF): lack of neurological toxicity.
- Int Conf AIDS. 1989 Jun 4-9;5:336 (abstract no. T.B.P.299). Unique Identifier : AIDSLINE ICA5/00164589
- Brew BJ; Keilp JG; Sadler AE; Krown SE; Anselmo W; Birnhak L; Sidtis JJ; Price RW; Bonnem E; Memorial Sloan-Kettering Cancer Center, NY, NY, USA
- OBJECTIVE: To assess the possibility of neurological toxicity of GM-CSF in neutropenic AIDS patients without dementia . METHODS: Patients enrolled in a phase 1 trial of GM-CSF as treatment for AIDS-related neutropenia were evaluated by quantitative neurological and neuropsychologica
- Occupational therapy for people with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:337 (abstract no. T.B.P.300). Unique Identifier : AIDSLINE ICA5/00164689
- Jacobs J; Lebowitz V; Center for Special Studies, NY, NY, USA
- OBJECTIVE: To maintain and/or improve functional independence and quality of life for HIV+/AIDS patients and their families. To be cost effective by decreasing frequency and length of hospital admissions and hours of home health care needed. METHODS: Occupational therapy as a component of Rehabilitation Medicine, assi
- Supervised physical exercise leads to psychological and immunological improvement in pre-AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:337 (abstract no. T.B.P.301). Unique Identifier : AIDSLINE ICA5/00164789
- Schlenzig C; Jager H; Rieder H; Hammel G; Popescu M; University of Heidelberg, Heidelberg, FRG
- OBJECTIVE: The immunological and psychological effects of therapeutically supervised physical exercise in HIV-AB positive individuals were investigated in a randomized controlled prospective study. METHODS: Twenty-eight HIV-AB positive patients were stratified according to the Walter-Reed-Staging- Classification (Stag
- Long term ribavirin treatment.
- Int Conf AIDS. 1989 Jun 4-9;5:337 (abstract no. T.B.P.302). Unique Identifier : AIDSLINE ICA5/00164889
- Banhegyi D; Lendvay J; Ujhelyi E; Fust G; Mihaly I; Varnai F; Institute for Infectious and Tropical Diseases, Postgraduate; Medical School, Budapest, Hungary
- OBJECTIVE: To evaluate clinical efficacy, safety and tolerance of long term ribavirin treatment. METHODS: Four patients /pts/ /stage III-3 stage IVA-1/ were treated with 600 mg/day ribavirin orally. Number and ratio of CD4+ and CD8+ lymphocytes, serum levels of immunoglobulin, neopterin and HIV p24 antigen were determ
- A phase I study of the safety and pharmacokinetics of soluble recombinant CD4 (rCD4) in patients with AIDS and ARC.
- Int Conf AIDS. 1989 Jun 4-9;5:337 (abstract no. T.B.P.303). Unique Identifier : AIDSLINE ICA5/00164989
- Allan JD; Kahn J; Hodges T; Sherwin S; Volberding P; Groopman J; New England Deaconess Hospital, Boston, MA, USA
- OBJECTIVE: To determine the safety and maximal tolerated dose of rCD4 and preliminary indications of antiviral effects of rCD4 in patients with AIDS & ARC. METHODS: A 2 center, phase I study with dose escalation and monitoring of the safety, pharmacokinetics, and clinical effect of rCD4 in 30 patients with AIDS or
- [Randomized trial of placebo versus high dosage acyclovir in HIV patients]
- Int Conf AIDS. 1989 Jun 4-9;5:337 (abstract no. T.B.P.304). Unique Identifier : AIDSLINE ICA5/00165089
- Chavanet P; Aho S; Mallet J; Waldner A; Buisson M; Bielefeld P; Portier H; Service des Maladies Infectieuses. Hopital du Hocage, BP1542,; 21034 Dijon, France
- [Generalized epileptic seizure after absorption of a toxic dose of zidovudine (a case report)]
- Int Conf AIDS. 1989 Jun 4-9;5:337 (abstract no. T.B.P.305). Unique Identifier : AIDSLINE ICA5/00165189
- Routy JP; Prajs E; Blanc AP; Drony S; Moriceau M; Sarrazin C; Hopital Cezanne, Aix en Provence, France
- Effective doses of AZT in HIV-1TP is associated with erythroid hypoplasia.
- Int Conf AIDS. 1989 Jun 4-9;5:338 (abstract no. T.B.P.306). Unique Identifier : AIDSLINE ICA5/00165289
- Huebsch LB; Garber G; Cameron DW; Aye MT; Department of Medicine, University of Ottawa and Ottawa General; Hospital, Ottawa, ON, Canada
- Idiopathic thrombocytopenic purpura (ITP) is not an uncommon finding in patients with HIV infection. The etiology of this thrombocytopenia remains unclear although immune complex disease has often been quoted as a contributory cause. Another possible mechanism is a defect in platelet production by HIV infected marrow
- Vitamin B 12 supplements in patients treated with Zidovudine.
- Int Conf AIDS. 1989 Jun 4-9;5:338 (abstract no. T.B.P.307). Unique Identifier : AIDSLINE ICA5/00165389
- Navarette MS; Gharakhanian S; Cardon B; Rozenbaum W; Infectious Disease Unit, Rothschild Hospital, Paris, France
- OBJECTIVE: To evaluate the efficacy of Vitamin B12 (Vit. B12) in the prevention of Zidovudine (Z) induced anemia. METHODS: AIDS or ARC patients (pts), receiving Z were randomized in 2 groups. One group was administered weekly injections of Vit. B12 (1000 mcg) as of the first week of their treatment. Both groups receiv
- Toxicity of Zidovudine (AZT) in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:338 (abstract no. T.B.P.308). Unique Identifier : AIDSLINE ICA5/00165489
- Clotet B; Gimeno JM; Jou A; Sirera G; Tor J; Dominguez M; Foz M; Infectious Diseases Unit. Hospital de Badalona Germans Trias i; Pujol, Barcelona, Catalonia, Spain
- OBJECTIVE: To report the hematologic toxicity observed in 32 AIDS patients treated with Zidovudine for a 3 month period. MATERIAL: Thirty-two AIDS patients, fulfilling the CDC criteria for AIDS, received AZT at a dosage regimen of 1200 mg/d. Hematolog
- [Prolonged corticotherapy in a dermatopolymyositis patient with HIV]
- Int Conf AIDS. 1989 Jun 4-9;5:338 (abstract no. T.B.P.309). Unique Identifier : AIDSLINE ICA5/00165589
- Roue R; Debord T; Dormont D; Vazeux R; Tisne B; Hopital Militaire Begin, 94160, Saint-Mandee
- Successful re-introduction of Zidovudine (AZT) after an allergic cutaneous reaction to AZT.
- Int Conf AIDS. 1989 Jun 4-9;5:338 (abstract no. T.B.P.310). Unique Identifier : AIDSLINE ICA5/00165689
- Mathieu-Boue A; Halfon P; Lebras P; Caquet R; CISIH, Paris Sud, France
- Allergic cutaneous reactions to AZT are uncommon and usually lead to definitive withdrawal of this drug. We report here a case of successful reintroduction schedule. A HIV seropositive 29 year old male (heterosexual exposure) with an oral hairy leucop
- Role of p24 Ag testing in patients on Zidovudine.
- Int Conf AIDS. 1989 Jun 4-9;5:339 (abstract no. T.B.P.311). Unique Identifier : AIDSLINE ICA5/00165789
- Hoy J; Chua J; Mijch A; Dimitrikakis M; Gust I; Lucas CR; Fairfield Infectious Diseases Hosp., Melbourne, Victoria,; Australia
- OBJECTIVE: To examine the role of regular measurement of serum p24 antigen (ag) in the management of HIV infected patients (pts) on Zidovudine ( AZT ). METHODS: From 1 June 1987, 95 pts (59 AIDS, and 36 ARC) have received AZT for 6-18 months, reviewed 2
- Change in beta-2 microglobulin (B2M) during Zidovudine (ZDV) therapy (RX) predicts clinical outcome.
- Int Conf AIDS. 1989 Jun 4-9;5:339 (abstract no. T.B.P.312). Unique Identifier : AIDSLINE ICA5/00165889
- Jacobson MA; Abrams D; Bacchetti P; Kocurek K; Wilber J; Moss AR; UCSF, SF General Hospital, San Francisco, CA, USA
- OBJECTIVE: Determine if changes during ZDV Rx in CD4 lymphocyte number or any of 4 serologic markers of HIV activity predict clinical outcome. METHODS: Whole blood CD4 lymphocytes (CD4) and serum p24 antigen (p24 Ag), beta-2 microglobulin (B2M), neopterin (NPT) and p24 antibody (p24 Ab) were measured pre-Rx and serial
- Use of multiparametric flow cytometry (lymphocyte p24-FCA) to evaluate azidothymidine therapy.
- Int Conf AIDS. 1989 Jun 4-9;5:339 (abstract no. T.B.P.313). Unique Identifier : AIDSLINE ICA5/00165989
- Ohlsson-Wilhelm BM; Cory JM; Kessler HA; Eyster ME; Rapp F; Landay A; M.S. Hershey Medical Center, The Pennsylvania State Univ.,; Hershey, PA, USA
- OBJECTIVE: To evaluate in a cross-sectional study the effect of azidothymidine ( AZT ) treatment on levels of active HIV-1 infection in AIDS patients. METHODS: A new test, lymphocyte p24-FCA, based on multiparametric flow cytometry, was used to quantita
- The inhibitory effects of AZT on HIV replication as determined by p24 antigen capture assays.
- Int Conf AIDS. 1989 Jun 4-9;5:339 (abstract no. T.B.P.314). Unique Identifier : AIDSLINE ICA5/00166089
- O'Shaughnessy MV; Lepine D; Wainberg M; Reudy J; Tsoukas C; Fanning M; Montemar J; Gelmon K; Federal Centre for AIDS, Ottawa, Canada
- A Canadian multicenter study assessed the possible toxic effects of AZT (Zidovudine) in 72 HIV-1 infected individuals. In this dose-escalating study, the patients were initially treated with 600 mg of drug/day for 18 weeks, 900 mg/day for another 9 we
- The effect of treatment with Zidovudine on immune system defects early in the course of HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:339 (abstract no. T.B.P.315). Unique Identifier : AIDSLINE ICA5/00166189
- Reiter WM; Cimoch PJ; Center for Special Immunology, Ft. Lauderdale, FL, USA
- OBJECTIVE: To study the immune system effects and toxicity of Zidovudine in patients with HIV infection and T4 lymphocyte counts between 200 and 400 cells/cu mm. METHODS: Patients were further evaluated by determination of HIV p24 antigen level, lymphocyte blastogenesis response to stimulation with the mitogen PHA, be
- Cutaneous reactions to trimethoprim-sulfamethoxazole (TMP-SMZ) in the treatment of Pneumocystis carinii pneumonia (PCP).
- Int Conf AIDS. 1989 Jun 4-9;5:339 (abstract no. T.B.P.316). Unique Identifier : AIDSLINE ICA5/00166289
- Schoefer H; Ochsendorf FR; Bauer H; Milbradt R; Stille W; Klinikum der J.W. Goethe Universitat, Dept. of Dermatology,; Frankfurt, FRG
- OBJECTIVE: To evaluate the prevalence, clinical morphology and course of cutaneous reactions to TMP-SMZ in the treatment of HIV-associated PCP. METHODS: Prospective clinical and morphological examination for untoward skin reactions in the treatment of 76 consecutive episodes of PCP in 61 patients (51 first manifestati
- Preliminary observations about the adverse effects of pefloxacin in the treatment of salmonella bacteremia in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:340 (abstract no. T.B.P.317). Unique Identifier : AIDSLINE ICA5/00166389
- Levi GC; Medeiros EA; Mendon:ca JS; Carvalho MC; Stefani HA; Pinczowski H; Servi:co de Molestias Infecciosas, Hospital do Servidor Publico; Estadual - Sao Paulo, Brazil
- We treated 3 patients with AIDS and positive blood cultures for Salmonella sp; in 2 cases S. typhimurium and, in one, S. dublin. They received pefloxacin orally, 800 mg/day, in 2 divided doses. They had a fast clinical and microbiological response, with disappearance of fever in few days and negativation of the blood
- Severe, acute trimethoprim-sulfamethoxazole (T-S) reaction mimics sepsis in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:340 (abstract no. T.B.P.318). Unique Identifier : AIDSLINE ICA5/00166489
- Johnson MP; Goodwin SD; Shands JW; College of Medicine, University of Florida; Gainesville, Florida,; USA
- OBJECTIVE: To describe a severe, acute syndrome of fever, hypotension, and pulmonary infiltrates in HIV infected patients receiving T-S. METHODS: We present the cases of two patients that we have seen and the four cases reported in the literature to describe this new syndrome. RESULTS: The clinical features occurred w
- [Hypolycemia and diabetes due to pentamidine mesylate during AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:340 (abstract no. T.B.P.319). Unique Identifier : AIDSLINE ICA5/00166589
- Perronne C; Bricaire F; Leport C; Vilde JL; Assan D; Assan R; Hopitaux Claude-Bernard
- Oral desensitization to sulfadiazine and trimethoprim-sulfamethoxazole (TMP-SMZ) in 4 patients with acquired immunodeficiency syndrome.
- Int Conf AIDS. 1989 Jun 4-9;5:340 (abstract no. T.B.P.320). Unique Identifier : AIDSLINE ICA5/00166689
- Moreno JN; Maggio CM; University of Miami School of Medicine, Miami, Florida, USA
- OBJECTIVE: To develop and evaluate an abbreviated oral desensitization program for patients with AIDS allergic to sulfadiazine and/or TMP-SMZ. METHODS: Four patients with prior allergic reactions to sulfadiazine (3) and TMP-SMZ (1) were identified. Allergic reactions included a severe generalized erythematosus rash wi
- A method for rapid oral desensitization of patients allergic to AZT.
- Int Conf AIDS. 1989 Jun 4-9;5:340 (abstract no. T.B.P.321). Unique Identifier : AIDSLINE ICA5/00166789
- MacFadden DK; Toronto Western Hospital, University of Toronto, Toronto,; Ontario, Canada
- Patients with HIV infection experience an increased frequency of allergic reactions to antimicrobial drugs with approximately 1% experiencing a sufficiently severe reaction to AZT to warrant discontinuation of the drug. In a population of 200 patients
- Recombinant interferon beta (ser) protects against Zidovudine-induced genetic damage in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:340 (abstract no. T.B.P.322). Unique Identifier : AIDSLINE ICA5/00166889
- Shafik H; Nokta M; Pollard RB; Department of Community, Environmental and Occupational Medicine,; University of Ain Shams, Cairo, Egypt
- This study was conducted to evaluate the in vivo geno-toxicity of Zidovudine (ZDV) in patients with AIDS. AIDS patients that were non-smokers and on ZDV (1200 mg/day) as a sole medication for 4 weeks to 7 months were recruited in the study. AIDS and ARC patients prior to receiving any therapy served as a negative cont
- Megaloblastic changes in the bone marrow of AZT treated AIDS-patients as a prognostic marker for need of blood transfusion.
- Int Conf AIDS. 1989 Jun 4-9;5:341 (abstract no. T.B.P.323). Unique Identifier : AIDSLINE ICA5/00166989
- Buys L; Van Den Berg-Wolf M; Pietersz R; Ten Veen J; Reesink H; Vereeniging voor Ziekenverpleging Prinsengracht, Amsterdam, The; Netherlands
- OBJECTIVE: To study the effects of one year azidothymidine ( AZT ) treatment on the erythropoiesis of AIDS-patients. PATIENTS AND METHODS: Twenty three male patients, classified as having AIDS underwent serial bone marrow aspirations during AZT treatmen
- The effects of PCP prophylactic agents on Zidovudine-induced anemias.
- Int Conf AIDS. 1989 Jun 4-9;5:341 (abstract no. T.B.P.324). Unique Identifier : AIDSLINE ICA5/00167089
- Rodgers P; Keyes C; Marte C; Wolbert J; Kelly J; Ribble D; Bellevue Hospital Center/ Community Health Project, NY, NY, USA
- OBJECTIVE: To review transfusion requirements in PCP prophylaxed patients receiving Zidovudine. METHOD: Through chart review, transfusion requirements for 169 patients on Zidovudine therapy for a median of 22 weeks were compared by type or absence of PCP prophylaxis. Eighty-eight patients received TMP/Sulfa, 59 patien
- Home transfusion for AIDS patients on Zidovudine.
- Int Conf AIDS. 1989 Jun 4-9;5:341 (abstract no. T.B.P.325). Unique Identifier : AIDSLINE ICA5/00167189
- Busalacchi M; Ivantic K; Gilson I; Visiting Nurse Association, Milwaukee, WI, USA
- OBJECTIVE: To describe a home blood transfusion (HT) program for AIDS patients (pts) on Zidovudine (ZDV) therapy. METHODS: AIDS pts with ZDV-related anemia (Hgb less than 8 gm%) were administered HT by home care nurses as an alternative to hospital transfusions (tx), usually as 2 units of WBC-poor packed RBC, under su
- The toxicity of Zidovudine in the treatment of patients with AIDS-related complex (ARC) and AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:341 (abstract no. T.B.P.326). Unique Identifier : AIDSLINE ICA5/00167289
- Stambuk D; Mir N; Hawkins D; Costello C; Gazzard B; St. Stephen's Hospital, London, England
- OBJECTIVE: To evaluate Zidovudine toxicity over a two year period of its clinical use in HIV patients. METHODS: Zidovudine-treated 351 ARC and AIDS patients, on 200mg 4-hourly oral regimen, have been monitored fortnightly for up to two years. RESULTS: Over a median follow-up of 8.5 months (range 1 - 23) Zidovudine was
- Polymyositis during Zidovudine therapy.
- Int Conf AIDS. 1989 Jun 4-9;5:341 (abstract no. T.B.P.327). Unique Identifier : AIDSLINE ICA5/00167389
- Sharpton T; Kaiser Foundation Hospital, Oakland, California, USA
- OBJECTIVE: To determine the incidence of polymyositis during Zidovudine ( AZT ) therapy. METHODS: A 12 month prospective followup of a cohort of 20 patients (pts) taking AZT. Creatine phosphokinase (CPK) was routinely monitored during visits and in pts
- Eosinophilia in HIV infected patients under Zidovudine therapy.
- Int Conf AIDS. 1989 Jun 4-9;5:341 (abstract no. T.B.P.328). Unique Identifier : AIDSLINE ICA5/00167489
- Dejace P; Morgan JE; O'Neil CE; Valainis G; Hyslop NH; Tulane University, New Orleans, LA, USA
- OBJECTIVE: To evaluate eosinophilia in patients with symptomatic HIV infection before and during Zidovudine (ZDV) therapy. METHODS: Forty nine individuals with late ARC or AIDS who had negative stools for parasites were studied. The natural history of eosinophilia, and absolute numbers of neutrophils and lymphocytes,
- AZT: Double edged sword.
- Int Conf AIDS. 1989 Jun 4-9;5:342 (abstract no. T.B.P.329). Unique Identifier : AIDSLINE ICA5/00167589
- Pivar I; Temoshok L; University of California School of Medicine, San Francisco, CA.,; USA
- OBJECTIVE: To provide information about patients stressors as well as positive perceptions regarding AZT that may influence their decision to take AZT, cooperate with treatment, and possibly their treatment outcome. METHODS: 103 seropositive homosexu
- Psoriasis in HIV AB positive drug abusers.
- Int Conf AIDS. 1989 Jun 4-9;5:342 (abstract no. T.B.P.330). Unique Identifier : AIDSLINE ICA5/00167689
- Masina M; Patrizi A; Costa AM; Ricchi E; Costigliola P; Chiodo F; Istituto di Clinica Dermatologica, Universita' di Bologna, Italy
- OBJECTIVE: To describe the onset of psoriasis during HIV infection in drug abuser patients. METHOD/RESULTS: We report on 5 Italian patients, aged between 22 and 34 years, who all had been drug abusers for more than 2 years. They have never been affected by psoriasis before diagnosis of HIV infection was made, and thre
- Phase I study of interferon alpha-2b (INTRON), Zidovudine and rGM-CSF in patients with AIDS-associated Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:342 (abstract no. T.B.P.331). Unique Identifier : AIDSLINE ICA5/00167789
- Fischl M; Uttamchandani R; Gagnon S; Thompson L; Santiago S; University of Miami, Miami, Florida, USA
- OBJECTIVE: To evaluate the efficacy and safety of rGM-CSF in combination with Intron and Zidovudine in patients with AIDS-associated Kaposi s sarcoma (KS). METHODS: Patients with KS and no active infections were enrolled. Intron was given as 12 mu Sq daily and Zidovudine-200mg orally every 4 hrs for 16 wks. Patients r
- A new more sensitive and highly specific anti HIV-1 assay based on recombinant proteins.
- Int Conf AIDS. 1989 Jun 4-9;5:342 (abstract no. T.B.P.332). Unique Identifier : AIDSLINE ICA5/00167889
- Beckford U; Berrisford C; Duncan RJ; Mackinlay L; Weston P; Tedder R; Wellcome Diagnostics, Beckenham, Kent, UK
- OBJECTIVE: To replace tissue culture raised viral lysate antigen with recombinant antigen in the Wellcozyme Monoclonal test and to further improve on the specificity seen in Wellcozyme competitive assays. METHODS: A recombinant DNA produced fusion protein containing the immunodominant regions of HIV-1 envelope and cor
- Update on program standardization among public health laboratories in the U.S.A. performing tests for human retroviruses.
- Int Conf AIDS. 1989 Jun 4-9;5:342 (abstract no. T.B.P.333). Unique Identifier : AIDSLINE ICA5/00167989
- Hausler WJ; DiSalvo A; Joseph J; Getchell J; State Hygienic Laboratory, IA, USA
- OBJECTIVE: To promote uniformity and assure quality of testing for HIV and other human retroviruses. METHODS: A survey of the fifty-four member laboratories of the Association of State and Territorial Public Health Laboratory Directors seeking information and data on human retrovirus programs was conducted in January
- T4a-internal image-bearing antibodies in sera of patients with HIV-1-infection.
- Int Conf AIDS. 1989 Jun 4-9;5:342 (abstract no. T.B.P.334). Unique Identifier : AIDSLINE ICA5/00168089
- Schedel I; Winkelmann P; Dreikhausen U; Flik J; Deicher H; Department of Internal Medicine, Division of Immunology, Medical; School Hannover, FRG
- Human immunodeficiency virus (HIV)-neutralizing antibodies could be detected in HIV-infected individuals by different groups. Obviously, the infection of the target-cell for HIV takes place by specific binding of the viral surface-glycoprotein (gp120) with the cellular CD4-receptor. This binding site is conserved in d
- Evaluation of different anti-HIV reagents that are available in Mexico.
- Int Conf AIDS. 1989 Jun 4-9;5:343 (abstract no. T.B.P.335). Unique Identifier : AIDSLINE ICA5/00168189
- Dominguez J; Morales C; Romero M; Moreno M; Orozco M; Centro Nacional de la Transfusion Sanguinea, Mexico, DF
- OBJECTIVE: To get to know percentage of sensitivity, specificity, false positives, false negatives of the reagents that are used in the Mexican health care system. METHOD: 6 traditional Elisa, 3 recombinant Elisa, 3 agglutination and 2 quick technology Elisa were evaluated with a known panel of 160 samples with AIDS,
- Which is the best laboratory marker when following HIV-positive person?
- Int Conf AIDS. 1989 Jun 4-9;5:343 (abstract no. T.B.P.336). Unique Identifier : AIDSLINE ICA5/00168289
- Reis M; Sprinz E; Kronfeld M; Azevedo M; Seadi C; Oravec R; Laboratorio Weimann de Porto Alegre, Brazil
- OBJECTIVE: Establish the best laboratory marker when following HIV-positive patients. METHODS: It were analyzed 60 ambulatory patients and 19 hospitalized HIV-positive patients. The following tests were executed Western-blot (WB- Dupont), Envacor HIV1 (EC-Abbott) and the presence of viral circulating antigen (HIV-Ag).
- Comparisons of commercially available test for HIV antibodies using Zambian sera.
- Int Conf AIDS. 1989 Jun 4-9;5:343 (abstract no. T.B.P.337). Unique Identifier : AIDSLINE ICA5/00168389
- Luo NP; Hira S; Siyambango J; Nshimbi R; Chipuka L; Macwacwa; University Teaching Hospital, Lusaka, Zambia
- OBJECTIVE: To compare the available test, the first generation, and confirmatory test with a view to decide the best Screening test and confirmatory test in Zambia . METHODS: 3 Panels of Sera were set. Each panel of Sera was screened for HIV antibodies using a set of test from the f
- Comparison of two HIV1 immunoblot techniques.
- Int Conf AIDS. 1989 Jun 4-9;5:343 (abstract no. T.B.P.338). Unique Identifier : AIDSLINE ICA5/00168489
- Wanzala P; Maitha G; Kenya Medical Research Institute, Kenya, Nairobi
- OBJECTIVE: To investigate the pattern of bands in strips of two electrophoretic immunoblot techniques to same sera. METHOD: 72 adult sera, 51 positive for HIV1 and 21 seronegative were tested with DUPONT and ANCOS Western blot electrophoretic techniques. RESULTS: Comparison of tests with DUPONT as reference test. (Pos
- Laboratory testing for HIV I antibody testing in California: analysis of current practices and improvement efforts.
- Int Conf AIDS. 1989 Jun 4-9;5:343 (abstract no. T.B.P.339). Unique Identifier : AIDSLINE ICA5/00168589
- Peddecord KM; Benenson A; Hofherr L; Ascher M; San Diego State University, San Diego, California, USA
- OBJECTIVE: This program uses HIV antibody testing as a model to develop and evaluate methods of monitoring and improving laboratory quality. METHOD: Using a blind proficiency test system, serum samples with known HIV content were submitted as clinical specimens by physicians, clinics and hospitals to their usual sourc
- Cross-reactivity between ELISA's for detection of HIV-1 and HIV-2.
- Int Conf AIDS. 1989 Jun 4-9;5:343 (abstract no. T.B.P.340). Unique Identifier : AIDSLINE ICA5/00168689
- Bouzas MB; Muchinik G; Picchio G; Simon F; Mathov I; Brun Vezinet F; IIHEMA, Academia Nacional de Medicina, Buenos Aires, Argentina
- OBJECTIVE: To study the cross-reactivity of HIV-1 and HIV-2 in ELISA assays. METHODS: Sixty sera from hemophiliacs were tested for antibodies HIV-1 (HIV-1 recombinant, Abbott) and confirmed by means of ENVACORE (Abbott) and RIPA. In all the sera, HIV-2 antibodies were determined using a commercial available anti-HIV-2
- Failure of ELISA and WB testing to detect HIV infected subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:344 (abstract no. T.B.P.341). Unique Identifier : AIDSLINE ICA5/00168789
- Mannella E; Ippolito G; Miceli M; Mirolo M; Pezzella M; Angeloni P; Italian Red Cross, National Center for Blood Transfusion, Rome,; Italy
- OBJECTIVE: To assess the efficacy of ELISA and WB test routinely used in laboratory setting to detect HIV infected subjects. METHODS: All sexual partners of seropositive blood donors were tested by ELISA and WB; most negative for anti-HIV were in situ hybridized (ISH) with an SP64 plasmid containing the nine-kilobase
- Correction of false-positive results of ELISA of immunodeficient state.
- Int Conf AIDS. 1989 Jun 4-9;5:344 (abstract no. T.B.P.342). Unique Identifier : AIDSLINE ICA5/00168889
- Kukaine R; Sochnev A; Svirska R; Burstein A; Shif B; Denisova A; August Kirchenstein Institute of Microbiology, Latvian SSR; Acad.Sci., Riga, USSR
- SUMMARY: A mass-scale serotesting of various subpopulations in order to detect HIV infection demonstrated that ELISA is a most widespread method of examination, and, irrespective of its high specificity, yields false-positive results in a definite percent of cases. METHODS: Serological testing for the presence of anti
- Serosurvey of women in a maternity ward.
- Int Conf AIDS. 1989 Jun 4-9;5:344 (abstract no. T.B.P.343). Unique Identifier : AIDSLINE ICA5/00168989
- Santos Pinto AS; Canas Ferreira WC; Prieto E; Sousa RA; Institute of Hygiene and Tropical Medicine, Ministry of health,; Cape Verde
- OBJECTIVE: To study the prevalence of hepatitis B markers and HIV antibodies in parturients receiving clinical care at a hospital in a Cape Verde island (West Africa). METHODS: During January and May 1988 serosurvey of the vertical transmission of hepatitis B virus was performed
- Lookback: an update on the New York experience.
- Int Conf AIDS. 1989 Jun 4-9;5:344 (abstract no. T.B.P.344). Unique Identifier : AIDSLINE ICA5/00169089
- Gaynor S; Kessler D; Andrews S; Berge P; DelValle C; New York Blood Center, New York, NY, USA
- OBJECTIVE: To evaluate results and assess costs of the Lookback Program. METHODS: A lookback of previous donations from 1358 anti-HIV positive blood donors identified since April, 1985 has been carried out. 203 hospitals in the greater New York region have been notified of receipt of 2417 components back to May, 1980.
- The Italian hemophilic register and natural history of HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:344 (abstract no. T.B.P.345). Unique Identifier : AIDSLINE ICA5/00169189
- Schinaia N; Ghirardini A; Valdarchi C; Gringeri A; Mariani G; Mannucci PM; Istituto Superiore di Sanita, Rome, Italy
- OBJECTIVES: To present the results of a nationwide survey of all population affected by congenital coagulation disorders, with the aim to evaluate the time-trend of the incidence of HIV-1 seropositivity and AIDS in the Italian Hemophilia population through a retrospective national cohort study. METHODS: This project i
- Transfusion-associated (T-A) AIDS cases in Italy.
- Int Conf AIDS. 1989 Jun 4-9;5:344 (abstract no. T.B.P.346). Unique Identifier : AIDSLINE ICA5/00169289
- Schinaia N; Valdarchi C; Istituto Superiore di Sanita, Rome, Italy
- OBJECTIVES: To present an update of the patients with AIDS due to blood transfusion, and to discuss the importance of an active surveillance system of T-A AIDS within the overall AIDS surveillance. The peculiarities of this specific surveillance will also be discussed. METHODS: A database has been created including al
- HIV-1 p24 antigen screening of male blood donors in localities with high HIV-1 antibody prevalence.
- Int Conf AIDS. 1989 Jun 4-9;5:344 (abstract no. T.B.P.347). Unique Identifier : AIDSLINE ICA5/00169389
- Busch M; Participating institutions in New York City, Miami, Detroit,; Seattle, San Francisco, Los Angeles, CA, USA
- OBJECTIVE: To assess the frequency of HIV-1 p24 antigen (Ag) positivity among male donors in high anti-HIV-1 prevalence areas in the city of San Francisco (SF) during a period with a high rate of HIV seroconversions. METHODS: The SF component of the TSS/NHLBI Donor Repository has 25,892 sera collected in late 1984-ear
- HIV infection in Western blot indeterminate blood donors.
- Int Conf AIDS. 1989 Jun 4-9;5:345 (abstract no. T.B.P.348). Unique Identifier : AIDSLINE ICA5/00169489
- Jackson B; Hanson M; Kwok S; Stramer S; Balfour HH; MacDonald K; St. Paul Red Cross, St. Paul, MN, USA
- OBJECTIVE: To determine whether U.S. Upper Midwest blood donors with indeterminate HIV-1 Western blot results are HIV-1 infected. METHODS: 187 volunteer blood donors who had tested repeatedly reactive by enzyme immunoassay (EIA) and had at least one HIV-1 characteristic band on Western blot (but not positive) were ask
- Multicenter evaluation of a recombinant based HIV-1/HIV-2 combination screening enzyme immunoassay.
- Int Conf AIDS. 1989 Jun 4-9;5:345 (abstract no. T.B.P.349). Unique Identifier : AIDSLINE ICA5/00169589
- Avilez F; Guertler L; Joller-Jemelka H; Ranger S; Siedl S; Simon F; Sondag D; Hampl H; Schoen B; Troonen H; European Clinical Study Group. Wiesbaden-Delkenheim, Federal; Republic of Germany (FRG)
- OBJECTIVE: To evaluate a newly developed screening assay which utilizes HIV-1 and HIV-2 recombinant proteins. A significant number of HIV-2 infected individuals would not be detected with current HIV-1 screening assays. METHODS: An enzyme immunoassay (EIA) was developed which utilizes both HIV-1 recombinant envelope a
- Human immunodeficiency virus antibody screening of blood donors - an international survey.
- Int Conf AIDS. 1989 Jun 4-9;5:345 (abstract no. T.B.P.350). Unique Identifier : AIDSLINE ICA5/00169689
- Perrault R; Mankikar S; Adatia A; The Canadian Red Cross Society, Ottawa, Canada
- Between October 1985 and March 1988, the Canadian Red Cross Society (CRCS) conducted three surveys on international practices of screening blood donors for anti-HIV. During this period, the reported cases of AIDS per 100,000 population increased from two in 1985 to six in 1988. At the same time, the mortality rate due
- Use of rapid assays for antibody to HIV in blood donors, persons practicing high risk behaviors and suspected AIDS cases in Ghana.
- Int Conf AIDS. 1989 Jun 4-9;5:345 (abstract no. T.B.P.351). Unique Identifier : AIDSLINE ICA5/00169789
- Mingle J; Mitchell S; Osei-Kwasi; Noguchi Memorial Institute for Medical Research, Accra, Ghana,; Africa
- OBJECTIVE: To evaluate three tests for antibody to HIV which do not require specialized equipment in three different populations in Ghana . METHOD: Seven laboratories in Ghana participated in the study. Two thousand specimens from 3 populations were tested with HIVCHEK, SERODIA and R
- The gift relationship revisited: HIV seroprevalence of blood donors and other low-risk groups in Africa.
- Int Conf AIDS. 1989 Jun 4-9;5:345 (abstract no. T.B.P.352). Unique Identifier : AIDSLINE ICA5/00169889
- Torrey BB; Mulligan M; Way P; Bureau of the Census, Washington, DC, USA
- OBJECTIVE: HIV survey data from 22 African countries reenforces the conclusion of Titmuss The Gift Relationship that the quality of donated blood varies considerably. METHOD: Compared HIV seroprevalence estimates from non-random sample surveys of blood donors and other low-risk groups (i.e., pregnant women) in the sa
- The impact of AIDS on blood transfusion services at the University Teaching Hospital, Lusaka.
- Int Conf AIDS. 1989 Jun 4-9;5:346 (abstract no. T.B.P.353). Unique Identifier : AIDSLINE ICA5/00169989
- Mwile A; University Teaching Hospital (UTH), Lusaka, Zambia
- OBJECTIVE: To describe the impact of AIDS on the Blood Transfusion services provided by the UTH. METHOD: The data was obtained from annual records and my full participation in the recruitment of blood donors. RESULTS: The number of blood units discarded on account of HIV positivity is rising and thus making it more di
- HIV antigen tests amongst new blood donors.
- Int Conf AIDS. 1989 Jun 4-9;5:346 (abstract no. T.B.P.354). Unique Identifier : AIDSLINE ICA5/00170089
- Das PC; de Vries AH; McShine RL; Smit Sibinga CT; Red Cross Blood Bank Groningen-Drenthe, Groningen, NL
- OBJECTIVE/METHOD: A window-phase (3-12 weeks) may exist following HIV infection when no antibody could be demonstrable but HIV antigen may appear in the blood. We have tested this possibility in first time (new) blood donors, since in our blood bank 60,000 annual donations have been followed over 3 years without add
- Indeterminate HTLV-I Western blot results in blood donors: absence of infectivity to recipients of blood.
- Int Conf AIDS. 1989 Jun 4-9;5:346 (abstract no. T.B.P.355). Unique Identifier : AIDSLINE ICA5/00170189
- Van Der Poel C; Lelie N; Reesink H; Ehlers P; Bakker E; Huisman H; Red Cross Blood Bank, Amsterdam, The Netherlands
- OBJECTIVE: To investigate if donor blood with indeterminate test results in HTLV-I Western blot (WB) transmits HTLV-I to recipients. METHODS: Serum samples from blood donors (n=5, 332) and recipients (n=392), who participated in a prospective study for posttransfusion hepatitis, were tested for HTLV-I antibodies with
- Case control study in HIV seropositivity in hemodialysis patients.
- Int Conf AIDS. 1989 Jun 4-9;5:346 (abstract no. T.B.P.356). Unique Identifier : AIDSLINE ICA5/00170289
- Salmao R; Accetturi C; Barata R; Salvador J; Longo IM; Mendes NF; Escola Paulista de Medicina and Casa de Saude Sante Marcelina; Sao Paulo SP Brazil
- To investigate the extent of HIV infection among dialysis patients, we studied 117 patients of the hemodialysis unit of the Santa Marcelina Hospital, east region of Sao Paulo city, to assess anti-HIV (ELISA and Western blot), immunological status, exposure to blood transfusion and time on hemodialysis. Twelve patients
- A clinical and serological follow-up of HIV 2 - positive patients from Guinea-Bissau (West Africa).
- Int Conf AIDS. 1989 Jun 4-9;5:346 (abstract no. T.B.P.357). Unique Identifier : AIDSLINE ICA5/00170389
- Costa C; Canas Ferreira WF; Champalimaud J; Mansinho K; Santos Pinto A; Dias F; Mendes P; Silva AP; Prieto E; Baptista JL; et al; Institute of Hygiene and Tropical Medicine-Dept. Microbiology and; Dept. Clinical Tropical Medicine-Ministry of Health,; Guinea-Bissau
- OBJECTIVE: - To establish the clinical and laboratorial features of HIV 2 infection and to determine parameters of these infection related to disease progression in people from Guinea-Bissau . METHODS: - 59 asymptomatic persons with documented (serological) HIV 2 infection in 1986
- Latex agglutination testing of whole blood for HIV-1 in the field.
- Int Conf AIDS. 1989 Jun 4-9;5:346 (abstract no. T.B.P.358). Unique Identifier : AIDSLINE ICA5/00170489
- Musgrave S; Biryahwaho B; Ojiwya A; Ndumu J; Downing R; Sempala S; Columbia University, New York, USA
- OBJECTIVE: To determine the reliability and practicability of using a Latex Agglutination (L.A.) test (RECOMBIGEN donated by Cambridge Bioscience) to test for HIV antibodies in a field serosurvey in Rakai, District, a highly endemic area of Uganda . METHODS: RECOMBIGEN L.A. is a rap
- Anti-HIV lookback programme of the Canadian Red Cross Society.
- Int Conf AIDS. 1989 Jun 4-9;5:347 (abstract no. T.B.P.359). Unique Identifier : AIDSLINE ICA5/00170589
- Hogan V; Mankikar S; Adatia A; Whittemore NB; The Canadian Red Cross Society, Ottawa, Canada
- Between November 1985 and December 1988, the Canadian Red Cross Society (CRCS) collected over 3.7 million units of blood. Of those, 395 (0.011%) were found to be Western blot (WB) positive. A total of 3.2 million units were collected from repeat donors, thus it is conceivable that some of the WB positive donors may ha
- Retrospective study of posttransfusion HIV infections.
- Int Conf AIDS. 1989 Jun 4-9;5:347 (abstract no. T.B.P.360). Unique Identifier : AIDSLINE ICA5/00170689
- Gathof B; Backer U; Gathof G; Gurtler L; Eberle J; Deinhardt F; Bavarian Red Cross Blood Transfusion Service, Munich, Federal; Republic of Germany
- OBJECTIVE: Between May 1, 1985 and Dec. 31, 1988 26 recipients (17 male, 5 female, 1 newborn male, 3 of unknown sex) of blood transfusions, were reported anti-HIV positive; the 285 donors involved were traced for testing for anti-HIV. METHODS: Donors who had not donated blood after the donation involved were tested fo
- Determination of erythrocyte adenosine deaminase activity in anti-HIV seronegative homosexual men with latent HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:347 (abstract no. T.B.P.361). Unique Identifier : AIDSLINE ICA5/00170789
- Ferrazzi M; De Rinaldis ML; Pezzella M; Caprilli F; Bozzi A; Strom R; Institute of Infectious Diseases, Policlinico Umberto I,; University of Rome, Rome, Italy
- OBJECTIVE: The aim of our research was to evaluate the erythrocyte, adenosine deaminase/pyruvate kinase activity (ADA/PK) in anti-HIV seronegative, non intravenous drug abusers, homosexual men with multiple partners (ELISA test, Western blot confirmed). METHODS: Erythrocytes from 21 heparinized blood samples were exam
- Clinical characterisation of HIV2 disease in West Africa.
- Int Conf AIDS. 1989 Jun 4-9;5:347 (abstract no. T.B.P.362). Unique Identifier : AIDSLINE ICA5/00170889
- Tumani Corrah Egboga AA; Wilikins AB; Gaye I; Whittle H; Greenwood B; Medical Research Council, Fajara, The Gambia
- OBJECTIVES: Particular attention is paid to the pattern of secondary infections in patients with HIV2 disease. METHODS: All cases suspected of having AIDS, AIDS selected complex or progressive generalized lymphopathy were included in the study. Serological diagnosis was made by Harvard methods priority testing in our
- Clinical evolution of 377 cases of LAS/ARC (follow - up since 6 - 48 months).
- Int Conf AIDS. 1989 Jun 4-9;5:347 (abstract no. T.B.P.363). Unique Identifier : AIDSLINE ICA5/00170989
- Ranieri S; Nicolli F; De Dona D; Bassi P; Ballardini G; Barelli A; Infectious Disease Division; Ravenna S. Maria delle Croci; Hospital, Italy
- OBJECTIVE/METHOD: The incidence of progression to AIDS of 377 patients with LAS/ARC (334 drug-addicts 2 drug-addicts and prostitutes, 14 homo/bisexual men, 3 homosexuals and drug-addicts, 10 haemophiliacs, 9 heterosexual contacts of drug-addicts HIV-Ab+, 4 individuals with no known risk factors and 1 subject infected
- Clinical and epidemiological spectrum of AIDS disease in Rio De Janeiro, Brasil
- Int Conf AIDS. 1989 Jun 4-9;5:347 (abstract no. T.B.P.364). Unique Identifier : AIDSLINE ICA5/00171089
- Sereno AB; Ismael C; Quinhoes EP; Ramos Filho CF; Perez MA; Weniger BG; Morais de Sa CA; Loures LA; Krebs JW; Hosp Universitario, Univ Fed do Rio de Janeiro (RJ), Brasil
- OBJECTIVE: To determine the clinical presentation--symptoms, signs, and diagnoses--of HIV+ and HIV- patients in order to provide an empirical basis for revision of the national case definition for AIDS surveillance in Brazil . METHODS: All consenting adults (n=496) admitted to medic
- AIDS associated glomerulopathy.
- Int Conf AIDS. 1989 Jun 4-9;5:348 (abstract no. T.B.P.365). Unique Identifier : AIDSLINE ICA5/00171189
- Marques LP; Santos OR; Lopes GS; Basilio de Oliveira CA; Oliveira AV; Riodja LS; Clinica Medica III-Escola de Medicina e Cirurgia, UNI-RIO, Brasil
- OBJECTIVE: To demonstrate the presence of glomerulopathy in HIV-infected patients. METHODS: We study 303 HIV-infected patients. The risk factors for HIV were: 221 homosexuals; 37 hemophiliacs; 14 unknown; 13 heterosexual contacts; 12 blood transfusions; 6 IV drug addicts. RESULTS: We found nephrotic syndrome in 3 (0.9
- Cervical lesions and HIV infection in a cohort of prostitutes in Kinshasa, Zaire.
- Int Conf AIDS. 1989 Jun 4-9;5:348 (abstract no. T.B.P.366). Unique Identifier : AIDSLINE ICA5/00171289
- Nsiangana Z; Nelson AM; Nzila N; Laga M; Edidi B; Marsella R; Mama Yemo Hospital, Kinshasa, Zaire
- OBJECTIVE: To describe the relation of cervical lesions and HIV infection in a cohort of prostitutes in Kinshasa, Zaire . METHODS: Cervical PAP smears were taken as part of the initial work up on 801 prostitutes enrolled in a cohort study in Kinshasa from May to December 1988. Data
- [Relationship between hepatitis B, HIV infections and acquired immunodeficiency syndrome]
- Int Conf AIDS. 1989 Jun 4-9;5:348 (abstract no. T.B.P.368). Unique Identifier : AIDSLINE ICA5/00171389
- Ouattara A; Meite M; Gody M; Manlan LK; de-The G; Institut Pasteur de Cote-d'Ivoire
- Lymphadenopathy and HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:348 (abstract no. T.B.P.369). Unique Identifier : AIDSLINE ICA5/00171489
- Basilio CA; Valle HA; Quinhoes EP; Fialho F; Sion FS; Morais de Sa CA; Gaffree & Guinle University Hospital - University of Rio de; Janeiro (UNI-RIO) - Brazil
- OBJECTIVE: To show the histopathological alterations of lymphnodes in HIV infected patients of groups III and IV according to CDC criteria. METHODS: We made a retrospective study of 80 biopsy and 28 necropsy material. We studied only cervical lymphnodes. The staining techniques used were: Hematoxilin-eosin, PAS, Groco
- Thymic pathology in pediatric AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:348 (abstract no. T.B.P.370). Unique Identifier : AIDSLINE ICA5/00171589
- Greco M; Thomas P; Mahnovski V; Magid M; Kahn E; Anderson V; New York University, NY, NY, USA
- OBJECTIVE: A variety of thymic lesions have been reported in AIDS. This more detailed and systematic description expands the previous reports. METHODS: We examined the thymuses of 19 infants and children with AIDS aged 2.5 mos to 5.5 years, at autopsy. One infant had a normal thymic shadow on chest roentgenogram at 4
- Delayed healing of infectious syphilitic lesions in HIV-infected Zambian men receiving appropriate penicillin treatment.
- Int Conf AIDS. 1989 Jun 4-9;5:349 (abstract no. T.B.P.371). Unique Identifier : AIDSLINE ICA5/00171689
- Hira SK; Mwendasilumba D; Macauca R; Perine PL; University Teaching Hospital, Lusaka, Zambia
- Twenty-two men with darkfield-confirmed primary or secondary genital syphilis were followed at weekly intervals to determine their response to treatment with 2.4 mega units of benzathine penicillin IM; seven had HIV infections confirmed by Western blot. Darkfield exam of lesion exudate was done on lesions persisting f
- Dermatitis of the face and yellow toe nail changes indicate progression to AIDS/OI in patients with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:349 (abstract no. T.B.P.372). Unique Identifier : AIDSLINE ICA5/00171789
- Morfeldt-Manson L; Julander I; Nilsson B; Karolinska Institute, Roslagstull Hospital, Stockholm, Sweden
- OBJECTIVE: To verify that seborrheic-like dermatitis of the face (DF) and yellow toe nail changes (YN) are clinical signs of deterioration in patients with HIV infection. METHODS: 77 consecutive patients with HIV infection and PGL were studied with regard to the presence/absence of DF and YN at the point of 30 months
- [A study of skin manifestations of HIV1 HIV2 seropositives]
- Int Conf AIDS. 1989 Jun 4-9;5:349 (abstract no. T.B.P.373). Unique Identifier : AIDSLINE ICA5/00171889
- Ndiaye B; Mboup S; Guiraud M; Kane A; Dieng MT; Universite de Dakar, Dakar, Senegal
- Clinical manifestations in African children.
- Int Conf AIDS. 1989 Jun 4-9;5:349 (abstract no. T.B.P.374). Unique Identifier : AIDSLINE ICA5/00171989
- Leoage P; Van de Perre P; Nitimans DG; Van Goethem C; Kestelyn P; Msengumuremyi F; Centre Hospitalier de Kigali, Kigali, Rwanda
- OBJECTIVE: To describe the clinical features of perinatally HIV-infected Rwandese children surviving over 5 years of age. METHODS: Sixteen HIV-seropositive children born to HIV-infected mothers, age 5 to 12 years old (9 girls and 7 boys; mean age 0.5 years) and diagnosed between 1984 and 1987 in Kigali,
- Gastrointestinal Kaposi sarcoma in AIDS - endoscopic findings.
- Int Conf AIDS. 1989 Jun 4-9;5:349 (abstract no. T.B.P.375). Unique Identifier : AIDSLINE ICA5/00172089
- Heise W; Mostertz P; Skorde J; Nehm K; Grosse G; L'age M; Auguste-Viktoria-Hospital, Berlin, West Germany
- OBJECTIVE: Frequency and distribution of gastrointestinal (GI) Kaposi sarcoma (KS) lesions, clinical sequelae and the value of endoscopic forceps biopsy shall be discussed. METHODS: In a prospective study, endoscopies of the upper and lower GI tract were done in 170 AIDS patients with GI symptoms. 39/170 (23%) had ski
- Severe reversible gastrointestinal dilatation associated with HIV1 infection.
- Int Conf AIDS. 1989 Jun 4-9;5:349 (abstract no. T.B.P.376). Unique Identifier : AIDSLINE ICA5/00172189
- Victorino R; Lucas M; Neto F; Moura MC; Faculty of Medicine of Lisbon, University Hospital of Santa; Maria, Department of Medicine 2, Av. Prof. Egas Moniz 1600; Lisbon, Portugal
- There is evidence of autonomic nerve dysfunction in patients with HIV infection and more recently extensive damage of the enteric autonomic nerves was documented in patients with HIV associated diarrhea. We report the case of a patient who presented to an intensive care unit with massive gastrointestinal dilation and
- The spectrum of clinical disease among Filipino cases.
- Int Conf AIDS. 1989 Jun 4-9;5:350 (abstract no. T.B.P.377). Unique Identifier : AIDSLINE ICA5/00172289
- Monzon OT; Basaca-Sevilla V; Hayes C; Capellan J; Manaloto C; Saniel MC; Department of Health Research Institute for Tropical Medicine,; Philippines
- OBJECTIVE: To determine the spectrum of clinical disease in Filipino AIDS cases. METHODS: The records of cases of AIDS among Filipino patients reported to the Department of Health AIDS Registry and referred to one of the authors were analyzed to determine the spectrum of secondary conditions seen. RESULTS: 11/13 cases
- Intrauterine HIV exposed children - results of a four-year prospective investigation.
- Int Conf AIDS. 1989 Jun 4-9;5:350 (abstract no. T.B.P.378). Unique Identifier : AIDSLINE ICA5/00172389
- Grosch-Worner I; Koch S; Vocks M; Schafer A; Habermehl KO; Mielke M; Universitats Klinikum Rudolf Virchow,; Kinderklinik/Frauen-Klinik, Standort Charlottenburg, Berlin,; Federal Republic of Germany
- OBJECTIVE: To report and discuss results to central questions like the transmission frequency, the difficulties in early and reliable definition of HIV-infection, the duration of latency period, the prevalence of symptomatic HIV-infection and early signs of symptomatic HIV-infection beyond the CDC-classification crite
- Pneumocystis carinii pneumonia (PCP) presenting as cystic apical lung lesions while on aerosolized pentamidine prophylaxis.
- Int Conf AIDS. 1989 Jun 4-9;5:350 (abstract no. T.B.P.379). Unique Identifier : AIDSLINE ICA5/00172489
- Siegel B; Flynn N; Martin W; Soehn M; Pomerantz S; University of California Davis Medical Center, Sacramento,; California USA
- We have been prophylaxing patients at high risk for PCP for almost 2 years with 300 mg of pentamidine aerosolized via a Respigard-II nebulizer q 2 weeks. Thus far we have had only two documented cases of PCP. CASE 1 was a 28 year old male who was diagnosed with AIDS secondary to wasting in 3/88. He was in a Zidovudine
- Occurrence of Kaposi sarcoma (KS) in patients treated with Zidovudine (AZT).
- Int Conf AIDS. 1989 Jun 4-9;5:350 (abstract no. T.B.P.380). Unique Identifier : AIDSLINE ICA5/00172589
- Mathieu-Boue A; Boue F; Halfon P; Delfraissy JF; CISIH, Paris Sud, France
- Among the 135 HIV positive patients treated with AZT in our center, 5 had KS at the initiation of treatment and of the 131 remaining patients, 4 developed KS during therapy. PATIENTS (pts): Median age was 41 (36-53), 2 were homosexuals, 2 had heterose
- Regression of Kaposi sarcoma and improvement of performance status by a combined interferon beta and Zidovudine therapy in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:350 (abstract no. T.B.P.381). Unique Identifier : AIDSLINE ICA5/00172689
- Brockmeyer NH; Mertins L; Malessa R; Biniek R; Goos M; University Essen, FRG
- Eight HIV infected patients with Kaposi sarcoma (KS) (stadium WR6), were treated with human fibroblast interferon beta and Zidovudine for a period of four months. KS were histologically verified, and localised at the hard palate, gum, at the plantar side of the feet, abdomen, and on the arms. In the last two months be
- [An acute encephalitis spontaneously regressive and disclosing an HIV-2 infection]
- Int Conf AIDS. 1989 Jun 4-9;5:350 (abstract no. T.B.P.382). Unique Identifier : AIDSLINE ICA5/00172789
- Rogez JP; Ranger S; Buffet-Janvresse C; Morcamp D; Denis F; Leroy J; Service de Medecine Interne, CHG Elbeuf, 76500 France
- Fluconazole therapy of patients with AIDS and cryptococcal meningitis and failed conventional antifungal therapy.
- Int Conf AIDS. 1989 Jun 4-9;5:352 (abstract no. W.B.P.1). Unique Identifier : AIDSLINE ICA5/00172989
- Rubin R; Robinson PA; Knirsch AK; Joseph JA; Massachusetts General Hospital, Boston, MA, USA
- OBJECTIVE: The study evaluates fluconazole (flu) therapy in patients (pts) who failed or could not tolerate conventional antifungal therapy (conv rx) because of its toxicity or serious contraindications. METHODS: Pts were enrolled if they met both of the stringent entry criteria: 1) life-threatening fungal infection;
- Itraconazole in the treatment of cryptococcal meningitis in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:352 (abstract no. W.B.P.2). Unique Identifier : AIDSLINE ICA5/00173089
- De Gans J; Portegies P; Tiessens G; Eeftinck Schattenkerk JK; van Ketel RJ; Academisch Medisch Centrum, 1105 AZ Amsterdam, The Netherlands
- OBJECTIVE: To assess the efficacy and tolerance of itraconazole (ICZ), a new antifungal triazole, in AIDS patients with cryptococcal meningitis. METHODS: Fourteen AIDS patients with cryptococcal meningitis were treated with ICZ. Nine patients (group I) received induction treatment with i.v. amphotericin B and oral flu
- Pulmonary involvement in cryptococcosis in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:352 (abstract no. W.B.P.3). Unique Identifier : AIDSLINE ICA5/00173189
- Cameron M; Bartlett J; Waskin H; Gallis H; Duke University, Durham, North Carolina, USA
- OBJECTIVE: To study the pulmonary manifestations of cryptococcosis in patients with AIDS. METHODS: A retrospective review was performed of patients with both HIV and cryptococcal infection. Twenty-eight patients were identified who met this criteria from 1983 to 1989. Nine patients had definite evidence of pulmonary C
- Prognostic factors of cryptococcal meningitis in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:352 (abstract no. W.B.P.4). Unique Identifier : AIDSLINE ICA5/00173289
- Kayembe-Kalambayi MD; Desmet P; Dept. of Internal Medicine, Cliniques Universitaires de Kinshasa,; Zaire
- AIM: Investigate which parameters could be indicative of a good or bad prognosis for cryptococcal meningitis in AIDS patients. METHODS: 34 HIV+ patients (21 males and 13 females) with cryptococcal meningitis confirmed by microscopy, antigen determination and Sabouraud culture were followed up at the University Hospita
- Intravenous and oral fluconazole (FCZ) for the treatment of acute cryptococcal meningitis.
- Int Conf AIDS. 1989 Jun 4-9;5:352 (abstract no. W.B.P.5). Unique Identifier : AIDSLINE ICA5/00173389
- Veeraf S; Davidson M; Mullen M; Boyle D; Raviglione M; Cortes H; Cabrini Medical Center, New York City, NY, USA
- OBJECTIVE: To assess the safety and efficacy of I.V. and oral FCZ in the therapy of acute cryptococcal meningitis (ACM). METHODS: Since 9/88, 7 consecutively diagnosed pts. with ACM were treated with FCZ IV (400 mg loading dose then 20 mg/d) for 2 weeks, then orally (200 mg/d) thereafter. RESULTS: 6/7 pts. responded.
- Serum cryptococcal antigen screening in the early diagnosis of cryptococcal infection in patients with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:352 (abstract no. W.B.P.6). Unique Identifier : AIDSLINE ICA5/00173489
- Masci J; Pierone G; Nicholas P; Mount Sinai Services, Elmhurst Hospital Center, Elmhurst, N.Y.,; USA
- OBJECTIVE: To determine if serum cryptococcal antigen is of value as a screening test for cryptococcal infection in patients with human immuno-deficiency virus (HIV) infection. METHODS: Serum cryptococcal antigen tests were performed on 88 HIV infected patients who were felt to be at risk for cryptococcal infection on
- Response of cryptococcal meningitis to anti-fungal therapy in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:353 (abstract no. W.B.P.7). Unique Identifier : AIDSLINE ICA5/00173589
- Nelson K E; Thaker GK; Merz W; Bartlett JG; Johns Hopkins Medical Institutions (JHMI), Baltimore, MD
- OBJECTIVE: To describe the natural history and response to antifungal therapy of cryptococcal meningitis in AIDS patients. METHODS: Medical records were reviewed and follow-up information obtained for all patients with disseminated cryptococcal infections at JHMI between Jan 1, 1985 and May 15, 1988. Patients were cha
- Spectrum of Cryptococcus neoformans infection in 68 HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:353 (abstract no. W.B.P.8). Unique Identifier : AIDSLINE ICA5/00173689
- Clark R; Greer D; Atkinson W; Valainis G; Hyslop N; Tulane/LSU ACTU, New Orleans, LA, USA
- OBJECTIVE: To review the spectrum of clinical features and results of therapy of Cryptococcus neoformans (Cn) infections in HIV infected (HIV+) patients. METHOD: Hospital records and X-rays of all HIV+ patients found to be infected with Cn by either microbiological or histopathologic evidence were reviewed retrospecti
- Fluconazole (FLU) treatment of persistent urinary cryptococcosis (PUC) after cryptococcal meningitis (CM).
- Int Conf AIDS. 1989 Jun 4-9;5:353 (abstract no. W.B.P.9). Unique Identifier : AIDSLINE ICA5/00173789
- Bozzette SA; Larsen RA; Chiu J; Leal ME; Large K; McCutchan JA; UC San Diego, California, USA
- OBJECTIVE: To study the response of PUC to FLU. PUC occurs in up to 30% of AIDS patients successfully treated for CM, is usually localized in the prostate, appears to resist further amphotericin B (AB) therapy, and is probably associated with relapse of CM. METHODS: Thirteen patients who completed standard therapy for
- Therapy (RX) of cryptococcal meningitis (CM) and cryptococcosis (C) in AIDS with oral itraconazole (IZ).
- Int Conf AIDS. 1989 Jun 4-9;5:353 (abstract no. W.B.P.10). Unique Identifier : AIDSLINE ICA5/00173889
- Denning DW; Tucker RM; Hamilton JR; Hanson LH; Stevens DA; Santa Clara Valley Med. Ctr., Stanford Univ., Institute Medical; Research, San Jose and Stanford, CA, USA
- OBJECTIVE: Despite poor CSF penetration, IZ is efficacious in CM models; we studied its efficacy in man as sole therapy. METHODS: We studied clinical, culture, serological responses to IZ (400mg/d) in 24 patients (pts) with AIDS: 18 with CM, 13 with cryptococcemia (CB), 5 with cryptococcuria (UC) and 3 with pulmonary
- Persistent Cryptococcus neoformans prostatic infection after successful treatment of meningitis.
- Int Conf AIDS. 1989 Jun 4-9;5:353 (abstract no. W.B.P.11). Unique Identifier : AIDSLINE ICA5/00173989
- Larsen R; Bozzette S; McCutchan JA; Chiu J; Leal M; Richman D; California Collaborative Treatment Group, USA
- OBJECTIVE: To assess the frequency of persistent C. neoformans infection in patients with AIDS after receiving apparently adequate treatment for meningitis. METHODS: All patients had AIDS and C. neoformans meningitis. Therapy consisted of either 2.0 grams of amphotericin B alone, or an adjusted minimum amphotericin B
- [Effectiveness of fluconazole compared with amphotericin b plus 5 flucytosine in intensive treatment and control of cryptococcal meningitis associated with AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:353 (abstract no. W.B.P.12). Unique Identifier : AIDSLINE ICA5/00174089
- Kahotwa M; Kapita B; Colebunders B; Mungieri A; Perriens J; Projet SIDA, Hopital Mama Yemo, Kinshasa, Zaire
- [Fluconazole in the treatment of cryptococcocal meninigitis in AIDS patients]
- Int Conf AIDS. 1989 Jun 4-9;5:354 (abstract no. W.B.P.13). Unique Identifier : AIDSLINE ICA5/00174189
- Kayembe K; Desmet P; Cliniques Universitaires de Kinshasa
- [Cryptococcosis in Burundi]
- Int Conf AIDS. 1989 Jun 4-9;5:354 (abstract no. W.B.P.14). Unique Identifier : AIDSLINE ICA5/00174289
- Floch JJ; Deppner M; Laroche R; Kadende P; Centre Hospitalo-Universitaire de Bujumbura/Burundi
- Cryptococcal disease and HIV infection in North Carolina.
- Int Conf AIDS. 1989 Jun 4-9;5:354 (abstract no. W.B.P.15). Unique Identifier : AIDSLINE ICA5/00174389
- Waskin H; Bartlett JA; Gallis HA; Duke University Medical Center Durham, North Carolina, USA
- OBJECTIVE: Evaluate characteristics of cryptococcal disease among persons with human immunodeficiency virus infection in rural, southeastern USA. METHODS: A retrospective review of clinical and laboratory records. RESULTS: From 1985 through 1988, the proportion of patients with cryptococcal disease who also had HIV in
- Cryptococcal meningitis in patients with AIDS. Diagnostic features and outcome in 8 cases.
- Int Conf AIDS. 1989 Jun 4-9;5:354 (abstract no. W.B.P.16). Unique Identifier : AIDSLINE ICA5/00174489
- Antonucci G; Armignacco O; Ippolito G; Bordi E; Galgani S; Grillo LR; Lazzaro Spallanzani Hospital for Infectious Diseases, Rome, Italy
- OBJECTIVE: To study clinical and laboratory features of cryptococcal meningitis (CM) in patients (pts) with AIDS. METHODS: Investigations involved clinical manifestation, tests on blood, CSF, other fluid and tissues, CT brain scans and/or cranial MRI. RESULTS: Among 101 patients with AIDS observed from 1984 to 1988, 8
- The limited value of routine serum antigen screening for cryptococcal infection.
- Int Conf AIDS. 1989 Jun 4-9;5:354 (abstract no. W.B.P.17). Unique Identifier : AIDSLINE ICA5/00174589
- Nelson MR; Smith DE; Hawkins D; Shanson D; Reed C; Gazzard BG; St Stephens Hospital, Fulham Road, London England
- OBJECTIVE: To assess the routine serum cryptococcal antigen as a screening procedure for diagnosis of cryptococcal infection. METHOD: All HIV Antibody positive patients over a three year period who had pyrexia of unknown origin or meningism underwent screening by serum cryptococcal antigen latex agglutination test. Al
- Cryptococcus neoformans pulmonary infection in 17 HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:354 (abstract no. W.B.P.18). Unique Identifier : AIDSLINE ICA5/00174689
- Clark R; Greer D; Valainis G; Hyslop N; Tulane/LSU ACTU, New Orleans, LA, USA
- OBJECTIVE: To review the presentation and clinical course of Cryptococcus neoformans (Cn) pulmonary infections in HIV infected (HIV+) patients. METHOD: Hospital records and chest X-rays of HIV+ patients known to have Cn pulmonary infection either by positive respiratory cultures or histopathologic evidence were retros
- Cryptococcosis in AIDS patients: clinical and therapeutic aspects.
- Int Conf AIDS. 1989 Jun 4-9;5:355 (abstract no. W.B.P.19). Unique Identifier : AIDSLINE ICA5/00174789
- Weinke T; Rogler G; Ortmann C; Pohle HD; Universitatsklinikum Rudolf Virchow, Freie Universitat Berlin,; West-Germany
- OBJECTIVE: Cryptococcus neoformans is a dangerous pathogen in AIDS patients and usually leads to disseminated disease. Prognosis depends on early diagnosis and early onset of proper treatment. We report an attempt at identifying characteristics that facilitate earlier recognition of cryptococcosis and describe the eff
- Cryptococcal meningitis in AIDS patients: incidence in Rio Grande do Sul (Brasil).
- Int Conf AIDS. 1989 Jun 4-9;5:355 (abstract no. W.B.P.20). Unique Identifier : AIDSLINE ICA5/00174889
- Kronfeld M; Sprinz E; Universidade Federal, Porto Alegre, Rio Grande do Sul, Brasil
- OBJECTIVE: Establish the incidence of cryptococcal meningitis in Rio Grande do Sul (RS) state. METHODS: It has been reviewed, at random, 80 registers of AIDS patients that have been hospitalized between January and November 1988 at HCPA. In 60 patients al lumbar puncture has been done and the liquor examined with the
- Therapeutic study in 35 patients with AIDS and cryptococcal meningitis.
- Int Conf AIDS. 1989 Jun 4-9;5:355 (abstract no. W.B.P.21). Unique Identifier : AIDSLINE ICA5/00174989
- Del Bianco R; Scapini R; Prado PS; Brunetti G; Leme SS; Mendon:ca M; Centro de Referencia e Treinamento em AIDS-Sao Paulo, Brazil
- OBJECTIVE: Analysis of the cerebrospinal fluids in 35 patients during therapeutic with Amphotericin B. METHODS: 35 patients were studied from October 86 until November 88. They were treated with AmphB and 5-fluorocytosine was also added in 19 patients (54,3%). The cerebrospinal fluids were obtained from all the patien
- Maintenance therapy with amphotericin B in AIDS patients with cryptococcal meningitis.
- Int Conf AIDS. 1989 Jun 4-9;5:355 (abstract no. W.B.P.22). Unique Identifier : AIDSLINE ICA5/00175089
- Clotet B; Villegas R; Sirera G; Dominguez M; Jou A; Gimeno JM; Foz M; Infectious Diseases Unit. Hospital de Badalona Germans Trias i; Pujol. Badalona. Barcelona. Catalonia. Spain
- OBJECTIVE: To report the efficacy of amphotericin B and Ketoconazole as a maintenance therapy for cryptococcal meningitis in an AIDS patient. MATERIAL/RESULTS: A 25 year-old intravenous drug abuser with antibodies to HIV presented a cryptococcal meningitis and received initial therapy with amphotericin B and flucytosi
- [Pulmonary toxoplasmosis during AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:355 (abstract no. W.B.P.23). Unique Identifier : AIDSLINE ICA5/00175189
- Marche C; Wolff M; Mayorga R; Matheron S; Salmon D; Matthiessen L; Claude B; Paris, France
- Long-term survival of AIDS patients successfully treated for toxoplasmic encephalitis.
- Int Conf AIDS. 1989 Jun 4-9;5:355 (abstract no. W.B.P.24). Unique Identifier : AIDSLINE ICA5/00175289
- Antoniskis D; Nussbaum JM; Dannemann BR; McCutchan JA; Chiu J; Leedom JM; LA Co.- USC, Los Angeles, California, USA
- OBJECTIVE: To describe long-term maintenance treatment and survival of AIDS patients (pts) with toxoplasmic encephalitis (TE). METHODS: Follow-up data [greater than 10 weeks (wks)] were available on 18 pts diagnosed at 4 centers since 1987. PTs received 6-8 wks primary therapy (Rx) with either 3 wks IV clindamycin (C)
- Toxoplasma gondii pneumonia (TGP) in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:356 (abstract no. W.B.P.25). Unique Identifier : AIDSLINE ICA5/00175389
- Oksenhendler E; Cadranel J; Datry A; Sarfati C; Marche C; Clauvel JP; Hopital Saint Louis, Paris, France
- Between 1984 and 1988, we observed TGP in 11 patients - 10 Europeans and 1 Haitian infected with HIV. 8 had AIDS prior to the diagnosis of TGP, 3 of them had non-Hodgkin lymphoma. Mean CD4 cell count was 30.5+/- 23.4 x 10(6)/1. The clinical features were: fever (11), dyspnea (10) and hemoptysis (2). Chest X-ray showed
- [Incidence of cerebral toxoplasmosis during AIDS: anatomo-clinical data. (Paris 1982-1985)]
- Int Conf AIDS. 1989 Jun 4-9;5:356 (abstract no. W.B.P.25). Unique Identifier : AIDSLINE ICA5/00175489
- Saimot AG; Matthiessen L; Matheron S; Leport C; Marche C; Vedrenne C; Hopital Bichat-Claude Bernard, Paris, France
- Cerebral toxoplasmosis in Danish AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:356 (abstract no. W.B.P.27). Unique Identifier : AIDSLINE ICA5/00175589
- Smith E; Pers C; Mathiesen L; Hvidovre Hosp., Univ. of Copenhagen, DK
- OBJECTIVE AND METHODS: To evaluate the diagnostic accuracy of cerebral toxoplasmosis in AIDS patients using clinical features, radiologic characteristics, serology and brain biopsy, we reviewed the charts from 1981-1988. RESULTS: Five (2%) patients had cerebral toxoplasmosis diagnosed at autopsy but were never treated
- [Cerebral toxoplasmosis and AIDS in Spain]
- Int Conf AIDS. 1989 Jun 4-9;5:356 (abstract no. W.B.P.28). Unique Identifier : AIDSLINE ICA5/00175689
- Ocana I; De Luis A; Ruiz I; Castro A; Romero J; Martinez-Vazquez JM; Departements de Medecine Interne et Neuroradiologie Hospital; Valle de Hebron
- Failure of high doses of roxithromycin (R) in AIDS patients with central nervous system toxoplasmosis (CNST).
- Int Conf AIDS. 1989 Jun 4-9;5:356 (abstract no. W.B.P.29). Unique Identifier : AIDSLINE ICA5/00175789
- Decazes JM; Doco-Lecompte T; Modai J; Department of Infectious Diseases, St Louis Hospital, Paris,; France
- AIM: To evaluate R, a new macrolide antibiotic, in CNST of AIDS patients with serious intolerance to conventional therapy. R has good activity in animal models of toxoplasmosis and high concentrations in human brain tissue has been demonstrated. METHODS: R (450 mg Q12h) was administered orally as the single agent, to
- Vesicle toxoplasmosis: a new sign of parasitic dissemination in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:356 (abstract no. W.B.P.30). Unique Identifier : AIDSLINE ICA5/00175889
- Noel G; Morisset R; Gregoire M; Lamarre L; Lapointe S; Universite de Montreal and Hotel-Dieu de Montreal, Montreal,; Quebec, Canada
- Protozoan affection remains the first killer of patients afflicted with AIDS. As of January 1989, 25 cases of Toxoplasmosis (T) were observed in such patients hospitalized in our institution. OBJECTIVE: To report a peculiar manifestation of T. among AIDS sufferers. METHODS: Since the first evidence of HIV seroconversi
- Therapeutic of toxoplasmic encephalitis in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:357 (abstract no. W.B.P.31). Unique Identifier : AIDSLINE ICA5/00175989
- Mendon:ca JS; Lobo IM; Stefani HN; Biancalana ML; Rodrigues GA; Levi GC; Servi:co de Molestias Infecciosas, Hospital do Servidor Publico; Estadual, Sao Paulo, Brazil
- Seventeen patients with AIDS and toxoplasmic encephalitis were studied regarding therapeutic response and adverse effects, diagnosis being established on clinical and tomographic basis. All patients had positive specific serological tests; IgM was always negative and IgG was always greater than 1/256; median CD4+ coun
- In vitro secretion of toxoplasma specific antibodies by peripheral blood cells from HIV1 infected subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:357 (abstract no. W.B.P.32). Unique Identifier : AIDSLINE ICA5/00176089
- Vendrell JP; Ducos J; Reyens J; Huguet MF; Cannat A; Serre A; Laboratoire d'Immunologie, Hopital Lapeyronie Montpellier,; France
- INTRODUCTION: Severe cerebral complications of Toxoplasmosis occur in 10 to 20% of AIDS patients. Serology is no great help for their diagnosis which relies on clinical and scanner arguments. We wondered whether specific B cells could not be present in the blood stream at earlier stages of active toxoplasmosis infecti
- The value of pyrimethamine/sulfadoxine (Fansidar) in the prevention of CNS-toxoplasmosis in AIDS-patients.
- Int Conf AIDS. 1989 Jun 4-9;5:357 (abstract no. W.B.P.33). Unique Identifier : AIDSLINE ICA5/00176189
- Balzer T; Rolfs A; Hoffken G; Deppermann KM; Hamm B; Riecken EO; Med.Clin., Freie Universitat Berlin, Federal Republic of Germany
- OBJECTIVE: Is FANSIDAR (FAN) 2 tbls/week sufficient for prevention of CNS-toxoplasmosis (C-Tox) in AIDS-patients (pts)? METHODS: Retrospective analysis of 16 pts. treated for C-Tox between 1986 and 1988. RESULTS: Sixteen human-immunodeficiency-virus-seropositive pts with acute C-Tox (typical intracerebral lesions in N
- Treatment of CNS toxoplasmosis in AIDS patients. results of prospective studies using pyrimethamine and macrolide antibiotics.
- Int Conf AIDS. 1989 Jun 4-9;5:357 (abstract no. W.B.P.34). Unique Identifier : AIDSLINE ICA5/00176289
- Ruf B; Pohle HD; Iglesias JR; Department of Internal Medicine, Rudolf Virchow University; Hospital (Wedding), Freie Universitat Berlin, FRG
- For treatment of cerebral toxoplasmosis pyrimethamine in combination with sulfonamides is commonly used. In our study the sulfonamide component was replaced by macrolide antibiotics. The results of treatment with pyrimethamine and with one or two macrolides were compared: with clindamycin and spiramycin (three drug re
- [Sites of toxoplasmosis in the digestive tract during AIDS. Anatomo-clinical study]
- Int Conf AIDS. 1989 Jun 4-9;5:357 (abstract no. W.B.P.35). Unique Identifier : AIDSLINE ICA5/00176389
- Marche C; Mayorga Ruben; Clair B; Trophilme D; Frottier J; Saimot AG; Hopital Bichat-Claude Bernard, Paris, France
- [Adenovirus isolated from the digestive tract of 20 AIDS patients, what is the clinical significance?]
- Int Conf AIDS. 1989 Jun 4-9;5:357 (abstract no. W.B.P.36). Unique Identifier : AIDSLINE ICA5/00176489
- Salmon D; Leport J; Garcia J; Leport C; Bricout F; Vilde JL; Hopital Claude-Bernard Paris, France
- Blastocystis hominis infection in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:358 (abstract no. W.B.P.37). Unique Identifier : AIDSLINE ICA5/00176589
- Rolston K; Rodriguez S; The University of Texas M.D. Anderson Cancer Center, Houston,; Texas, USA
- Although associated with some instances of human gastrointestinal disease, the pathogenicity of Blastocystis hominis is still under question. OBJECTIVE: - To evaluate the pathogenic potential of B. hominis in AIDS patients. METHODS: - The records of HIV-infected individuals whose stool specimens contained B. hominis (
- Variable localization of intestinal cryptosporidiosis in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:358 (abstract no. W.B.P.38). Unique Identifier : AIDSLINE ICA5/00176689
- Heller TD; Tierney AR; Kotler DP; St Luke's-Roosevelt Hospital Center, Columbia University, New; York, NY, USA
- OBJECTIVE: To examine the localization of cryptosporidial (Crypto) infection in the gastrointestinal tracts of patients with AIDS. METHODS: In a retrospective review of biopsies from 25 AIDS patients with Crypto, the small intestine was the primary site of involvement in 16 patients, the colon was the primary site of
- Colonoscopic etiological diagnosis of diarrhea in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:358 (abstract no. W.B.P.39). Unique Identifier : AIDSLINE ICA5/00176789
- Bonfim de Lima D; Jurado E; Favoreto C; Treistman M; Passos R; Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil
- From August 1985 to September 1988, 18 patients were studied by the same physicians at the Department of Infectious Diseases and private clinic. They presented diarrhoea for more than 30 days. Among them were 14 homosexual men, 2 blood receivers and 2 women married with bisexual men. After negative laboratorial invest
- Incidence of infectious gastroenteritis in Spanish AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:358 (abstract no. W.B.P.40). Unique Identifier : AIDSLINE ICA5/00176889
- Mallolas J; Moreno A; Miro JM; Gatell JM; Latorre X; Soriano E; Infectious Diseases Unit. Hospital Clinic. University of; Barcelona. Barcelona, Spain
- OBJECTIVE: To describe the characteristics of the infectious gastroenteritis (IG) in 226 Spanish AIDS cases. METHODS: Since 1984, all patients who fulfilled the CDC criteria for AIDS case definition were prospectively followed. Seventy four (33%) were male homosexuals (HMS) and 132 (60%) drug addicts (DA). RESULTS: Fi
- Gastrointestinal multiinfection in AIDS patient: a case report.
- Int Conf AIDS. 1989 Jun 4-9;5:358 (abstract no. W.B.P.41). Unique Identifier : AIDSLINE ICA5/00176989
- Kronfeld M; Sprinz E; Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil
- OBJECTIVE: Report a gastrointestinal multiinfection in AIDS patient in Rio Grande do Sul (RS) state. CASE REPORT: A 29 years old, white, drug addict and promiscuous was hospitalized with a copious, explosive, bloody diarrhea. First stool analysis revealed Strongyloides stercoralis and Ascaris lumbricoides. Thiabendazo
- Rotavirus as a diarrhea agent in adult AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:358 (abstract no. W.B.P.42). Unique Identifier : AIDSLINE ICA5/00177089
- Slim J; DeLuca P; Perez G; Shah J; DeLuca A; Saint Michael's Medical Center, Newark, New Jersey, USA
- OBJECTIVE: To determine incidence and importance of rotavirus as a cause of diarrhea in AIDS patients. METHODS: Stool samples were assayed by latex agglutination and Elisa technique for the presence of rotavirus. These stool samples were collected from 12/88 through 1/89 when the incidence of rotavirus was at its heig
- [Effectiveness of long acting somatostatin (SMS 201 955) in the treatment of diarrheas and cytopenias in 2 AIDS patients]
- Int Conf AIDS. 1989 Jun 4-9;5:359 (abstract no. W.B.P.43). Unique Identifier : AIDSLINE ICA5/00177189
- Routy JP; Latreille J; Phaneuf D; Neemeh JA; Monte M; Beaulieu R; H\lcotel Dieu Montreal H2W1T8 Canada
- Gastric leishmaniasis in an AIDS-patient.
- Int Conf AIDS. 1989 Jun 4-9;5:359 (abstract no. W.B.P.44). Unique Identifier : AIDSLINE ICA5/00177289
- Pesce A; Vinti H; Taillan B; Saint-Paul MC; Marty P; Le Fichoux Y; Cassuto JP; C.H.R.U. Nice, France
- Visceral leishmaniasis has been previously described in HIV seropositive patients and even proposed as a new opportunistic disease. A 28-old patient, seropositive for HIV, followed since 1985, was admitted for weight loss, epigastric pain. Two years ago, he had developed cerebral toxoplasmosis. Since June 1987, he rec
- Successful use of hyperimmune bovine colostrum to treat Cryptosporidium infection in an AIDS patient.
- Int Conf AIDS. 1989 Jun 4-9;5:359 (abstract no. W.B.P.45). Unique Identifier : AIDSLINE ICA5/00177389
- Ungar B; Ward D; Fayer R; Quinn C; Uniformed Services University of the Health Sciences, Bethesda,; MD, USA
- Cryptosporidium is a protozoan parasite of the human gastrointestinal tract which can cause life-threatening diarrhea in immunodeficient patients. Although close to eighty agents have been tried with occasional anecdotal success, treatment remains primarily limited to hydration. We describe a 38-year-old homosexual ma
- A comparison of electron microscopy (E/M) and light microscopy (L/M) in the diagnosis of cryptosporidial and blastocystis infection.
- Int Conf AIDS. 1989 Jun 4-9;5:359 (abstract no. W.B.P.46). Unique Identifier : AIDSLINE ICA5/00177489
- Connolly GM; Tovey G; Gazzard BG; St. Stephen's Hospital, London. United Kingdom
- OBJECTIVE: To assess the value of L/M and E/M in the identification of apparent cryptosporidial infection. METHODS: Rectal biopsy and stool specimens were examined by L/M and E/M from 40 AIDS patients with diarrhoea (at least 3 liquid motions/day for longer than one month). RESULTS: E/M confirmed the presence of crypt
- Treatment of cryptosporidial infection with recombinant interleukin-2 (rIL-2).
- Int Conf AIDS. 1989 Jun 4-9;5:359 (abstract no. W.B.P.47). Unique Identifier : AIDSLINE ICA5/00177589
- Connolly GM; Owen SL; Hawkins DA; Gazzard BG; St. Stephen's Hospital, London, England. United Kingdom
- OBJECTIVE: To assess the response of cryptosporidial diarrhoea to rIL-2. METHODS: Three patients with cryptosporidial diarrhoea (present in 3 stool specimens and rectal biopsy) had stool volumes measured for four days prior and seven days after a course of intravenous rIL-2 (400ug over 2 hours daily for 14 days). A pa
- Gastrointestinal cryptosporidiosis in Rio Grande do Sul (RS) state: the highest incidence.
- Int Conf AIDS. 1989 Jun 4-9;5:359 (abstract no. W.B.P.48). Unique Identifier : AIDSLINE ICA5/00177689
- Sprinz E; Kronfeld M; Capobianco K; Barth A; Petrillo V; Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil
- OBJECTIVE: Establish the incidence of gastrointestinal cryptosporidiosis in AIDS patients in RS. METHODS: It was reviewed, at random, 50 registers of AIDS inpatients at HCPA between July and November 1988. 8 cases were excluded because they did not meet the inclusion criteria (at least 4 stool analysis for cryptospori
- Atypical secondary syphilis in HIV seropositive patients.
- Int Conf AIDS. 1989 Jun 4-9;5:360 (abstract no. W.B.P.49). Unique Identifier : AIDSLINE ICA5/00177789
- Caumes E; Janier M; Janssen F; Rybojad M; Dallot A; Morel P; Department of Dermatology, Hopital Saint-Louis, Paris, France
- OBJECTIVE: To describe secondary syphilis in 8 HIV-seropositive patients. METHODS: Retrospective study of clinical, serological, bacteriological and histopathological data in 8 consecutive patients (HIV +) seen in our department from 1984 to 1988 for a secondary syphilis. RESULTS: Patients: 8 males (mean age: 36, 8 +/
- Neurosyphilis in HIV-infected patients: evidence of unreliable serologic responses.
- Int Conf AIDS. 1989 Jun 4-9;5:360 (abstract no. W.B.P.50). Unique Identifier : AIDSLINE ICA5/00177889
- Malessa R; Bahro M; Brockmeyer N; Biniek R; Schwendemann G; Dept. of Neurology, University Clinic, Essen, FRG
- OBJECTIVE AND METHODS: The combined infection with Treponema pallidum and HIV by unknown interaction leads to an atypical presentation of Neurosyphilis (NS), but reagin and treponemal antibody tests have remained the cornerstone of diagnosis. We report on 4 HIV-infected men (C
- Syphilitic myelopathy with human immunodeficiency virus: a treatable cause of spinal cord disease.
- Int Conf AIDS. 1989 Jun 4-9;5:360 (abstract no. W.B.P.51). Unique Identifier : AIDSLINE ICA5/00177989
- Berger JR; Hensley G; Moskowitz L; Department of Neurology, University of Miami School of Medicine,; Miami, Florida, USA
- Three individuals with syphilitic myelopathy occurring in association with human immunodeficiency virus (HIV) infection are described. One patient responded dramatically to high dose intravenous penicillin therapy. In the other two patients, syphilitic spinal cord involvement was confirmed at autopsy by the presence o
- History of and conventional tests for syphilis in HIV-1 seropositive homosexual men in the Baltimore MACS.
- Int Conf AIDS. 1989 Jun 4-9;5:360 (abstract no. W.B.P.52). Unique Identifier : AIDSLINE ICA5/00178089
- Alwood K; Fox R; Hook E; McArthur JH; Starkey D; Saah A; The Johns Hopkins Medical Institutions, Baltimore, MD, USA
- OBJECTIVE: To determine the validity of syphilis testing in HIV-1 seropositive homosexual men with self-reported syphilis history. METHODS: Sixty HIV-1 seropositive Rapid Plasma Reagin (RPR) - men in the Baltimore MACS were stratified by self-reported history of syphilis and tested for evidence of past or present infe
- An association of syphilis episodes and human immunodeficiency virus (HIV) infection in sexually transmitted disease (STD) patients in Los Angeles County.
- Int Conf AIDS. 1989 Jun 4-9;5:360 (abstract no. W.B.P.53). Unique Identifier : AIDSLINE ICA5/00178189
- Rose TP; Ford W; Kerndt P; Mohilef E; Onorato I; Los Angeles County Department of Health Services, Los Angeles,; California, USA
- OBJECTIVE: To determine if an association exists between a history of syphilis episodes and HIV seropositivity. METHODS: Clients participating in confidential HIV testing in Los Angeles County STD clinics between July 1 and December 15, 1988, were interviewed by pretest counselors about their history of STDs and high
- Seroreversion of treponemal tests during HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:360 (abstract no. W.B.P.54). Unique Identifier : AIDSLINE ICA5/00178289
- Haas JS; Bolan G; Larsen S; Clement M; Moss A; San Francisco General Hospital & UCSF, SF, CA, USA
- OBJECTIVE: To evaluate the sensitivity of treponemal tests (i.e. FTA-ABS and/or MHA-TP) for syphilis in individuals with HIV infection. METHODS: Subjects -- 110 homosexual men with a documented history of syphilis, who enrolled in a longitudinal cohort between 1982-85. Syphilis serology done on entry into cohort was c
- Meningovascular syphilis in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:361 (abstract no. W.B.P.55). Unique Identifier : AIDSLINE ICA5/00178389
- Saint-Marc T; Garnier JL; Livrozet JM; Touraine JL; Meignan F; Pavillon P, Hopital Edouard Herriot, 69 437 Lyon Cedex 03; France
- HIV may alter the natural history of syphilis by increasing the propensity of the disease to progress to neurosyphilis. Meningeal inflammation induced by either pathogen (HIV and T. pallidum) could allow the other agent to penetrate further into the CNS. We reported two cases of meningovascular syphilis in homosexual
- Serological and cerebrospinal fluid parameters related to syphilis in HIV asymptomatic seropositives.
- Int Conf AIDS. 1989 Jun 4-9;5:361 (abstract no. W.B.P.56). Unique Identifier : AIDSLINE ICA5/00178489
- Berger JR; McCarthy M; Fletcher MA; Klimas N; Lo E; Pall L; Department of Neurology, University of Miami School of Medicine,; Miami, Florida, USA
- Serological and CSF parameters associated with syphilis were analyzed in asymptomatic HIV-seropositives. Thirty-four of 86 (39.5%) reported a remote history of syphilis. Serum FTA-ABS was positive in 25/34 (73.5%) of those with a positive history and in 4/52 (7.7%) without a history. Only 8 subjects had a positive ser
- Syphilis treatment response in HIV infected persons.
- Int Conf AIDS. 1989 Jun 4-9;5:361 (abstract no. W.B.P.57). Unique Identifier : AIDSLINE ICA5/00178589
- Telzak E; Zweig M; Harrison J; Stoneburner R; Schultz S; New York City Department of Health (NYCDOH), NY, NY, USA
- OBJECTIVE: To determine whether HIV infected persons treated for primary (PS) or secondary syphilis (SS) have a modified rapid plasma reagin (RPR) response and thus are more likely to be considered treatment failures compared to HIV-patients with a comparable stage of treated syphilis. METHODS: Medical records were re
- Retreatment of syphilis in HIV positive patients.
- Int Conf AIDS. 1989 Jun 4-9;5:361 (abstract no. W.B.P.58). Unique Identifier : AIDSLINE ICA5/00178689
- Phillip H; Harris JR; Goldmeier D; The Praed Street Clinic, St Mary's Hospital, London, W2 1NY,; United Kingdom
- OBJECTIVE: Treponemes can persist in the CNS following standard treatment of early syphilis with benzathine or procaine penicillin. Approximately 50% of homosexuals with AIDS have had syphilis, and it is possible that persisting treponemal infection contributes to the neurological manifestations of AIDS. We are perfor
- Failure of benzathine penicillin to eradicate syphilis in HIV positive patients.
- Int Conf AIDS. 1989 Jun 4-9;5:361 (abstract no. W.B.P.59). Unique Identifier : AIDSLINE ICA5/00178789
- Hay P; Kitchen V; Harris JR; Goldmeier D; The Praed Street Clinic, St Mary's Hospital, London, W2 1NY,; United Kingdom
- OBJECTIVE/METHOD: An increasing number of reports document failure when using benzathine penicillin to treat early syphilis in HIV positive patients. Alternative regimes that have been suggested include procaine penicillin with probenecid, oral amoxicillin with probenecid, and intravenous benzylpenicillin. We reviewed
- HIV-related primary medical care for intravenous drug users (IVDU) in a methadone maintenance treatment program (MMTP).
- Int Conf AIDS. 1989 Jun 4-9;5:361 (abstract no. W.B.P.60). Unique Identifier : AIDSLINE ICA5/00178889
- Selwyn PA; Feingold AR; Iezza A; Satyadeo M; Shaw JF; Torres R; Montefiore Medical Center/Albert Einstein College of Medicine,; Bronx, NY, USA
- OBJECTIVE: To evaluate the feasibility of providing on-site HIV-related primary medical care for IVDU s enrolled in a longterm outpatient MMIP in New York City. METHODS: IVDU s with or at risk for HIV infection were offered on-site primary medical care at a Bronx MMTP. Patients with AIDS or advanced HIV disease (CDC I
- Report on a statewide survey to determine levels of outpatient clinic/ambulatory care services for persons with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:362 (abstract no. W.B.P.61). Unique Identifier : AIDSLINE ICA5/00178989
- Young SR; Grant CM; New Jersey State Department of Health, New Jersey, USA
- OBJECTIVE: To determine the configuration and cost of needed ambulatory services for HIV infected persons in New Jersey which has the fourth highest number of AIDS cases and significant HIV seroprevalence. METHOD: Data was obtained from a statewide survey of 16 hospital- and community-based ambulatory health centers c
- A collaborative approach to primary outpatient oriented care of patients with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:362 (abstract no. W.B.P.62). Unique Identifier : AIDSLINE ICA5/00179089
- Bartlett K; Hadley D; Jensen PC; Departments of Nursing and Medicine, Veterans Administration; Medical Center and The University of California, San Francisco,; California, USA
- The San Francisco Veterans Administration Medical Center (SFVAMC) is a 300 bed teaching hospital with a traditional emphasis on inpatient care that is located in an area of high endemicity for HIV infection. The Infectious Diseases Clinics provide primary outpatient care for the majority of HIV-infected patients seen.
- Comprehensive HIV case management protocols for 26 Northern California counties.
- Int Conf AIDS. 1989 Jun 4-9;5:362 (abstract no. W.B.P.63). Unique Identifier : AIDSLINE ICA5/00179189
- Blomberg PS; Flynn N; Sacramento AIDS Foundation, Sacramento, CA, USA
- OBJECTIVE: To develop for Northern California area physicians and hospitals HIV education and a comprehensive case management protocol for HIV, ARC/AIDS patients. Northern California has had 600 cases of AIDS recorded since 1983. Projections indicate 1,500 cases of AIDS and over 12,000 HIV cases in the region by 1992.
- Visiting physician service for AIDS patients in Nassau County.
- Int Conf AIDS. 1989 Jun 4-9;5:362 (abstract no. W.B.P.64). Unique Identifier : AIDSLINE ICA5/00179289
- Feleke G; Forlenza S; Agins BD; AIDS Program, Nassau County Medical Center (NCMC), East Meadow,; NY, USA
- OBJECTIVE: To describe a visiting physician service for AIDS patients in suburban Nassau County. METHODS: Prospective records were kept of patient characteristics and each physician intervention. RESULTS: In 1988 a visiting physician service for PWAs was created at NCMC and supported by the Robert Wood Johnson Foundat
- Home transfusion: A safe, effective alternative to traditional care.
- Int Conf AIDS. 1989 Jun 4-9;5:362 (abstract no. W.B.P.65). Unique Identifier : AIDSLINE ICA5/00179389
- Peugeot RL; Atlanta Home Care, Atlanta, Georgia, USA
- OBJECTIVE: To describe an active, safe and effective home blood transfusion program designed to meet the needs to the HIV + patient experiencing anemia. METHODS: We set up a home blood transfusion program designed to meet the needs of the anemic HIV + patient who often requires 3-4 units of Packed Red Cells per episod
- At-home care of terminal AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:362 (abstract no. W.B.P.66). Unique Identifier : AIDSLINE ICA5/00179489
- Garde C; Arrizabalaga C; Arrizabalaga J; Iribarren JA; Zulaica D; Hospital Nuestra Senora de Aranzazu. Servicio Vasco de Salud.; Osakidetza. San Sebastian. Spain
- OBJECTIVE: Evaluation of the problems of this new form of care of AIDS patients. METHOD: The hospital team included a physician and a nurse who were charged with at-home care of AIDS patients, particularly terminal cases. The number of visits was determined by the patient s individual needs, and the objective of each
- A survey of complementary AIDS/HIV therapies and services.
- Int Conf AIDS. 1989 Jun 4-9;5:363 (abstract no. W.B.P.67). Unique Identifier : AIDSLINE ICA5/00179589
- Ostrow D; Heirich M; Shefner A; University of Michigan, Ann Arbor, MI, USA
- OBJECTIVES: To determine the range of information and services provided by complementary/alternative AIDS/HIV therapy organizations and practitioners, the range of therapies in use beyond standardized medical treatments, and their willingness to participate in a computerized database of complimentary therapies. METHOD
- Effect of cardiovascular conditioning in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:363 (abstract no. W.B.P.68). Unique Identifier : AIDSLINE ICA5/00179689
- Keyes C; Rodgers P; Wolbert J; Marte C; Kelly J; Ribble D; Bellevue Hospital/Community Health Project, NY, NY, USA
- OBJECTIVE: Clinical and immunologic evaluation of cardiovascular conditioning in persons with HIV infection. METHODS: 28 patients (6AIDS, 18ARC, 4PGL) were randomized to 1 of 2 groups for cardiovascular conditioning in a crossover trial of 16 weeks duration. Treatment phase consisted of 3-1hr periods/wk of aerobic exe
- Clinical value of a Tac-inhibitory activity produced spontaneously by adherent cells of HIV-infected subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:363 (abstract no. W.B.P.69). Unique Identifier : AIDSLINE ICA5/00179789
- Ammar A; Cibert C; Bertoli AM; Meyer P; Jasmin C; Georgoulias V; Oncogenese Appliquee, (INSERM U268), Hop. Paul Brousse,; 14-16, av. P.V. Couturier, 94804 Villejuif. France
- OBJECTIVE: Determine the clinical value of a Tac-inhibitory activity produced during HIV infection. METHODS: Peripheral blood adherent cells were isolated from 15 asymptomatic seropositives, 11 LAS, 4 ARC and 5 AIDS patients, and 24h-conditioned media were prepared without any cell stimulation under serum-free conditi
- Appearance of p24 antigen and decline in T4 cell counts as predictive markers for AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:363 (abstract no. W.B.P.70). Unique Identifier : AIDSLINE ICA5/00179889
- Eyster ME; Goedert J; Pennsylvania State University, Hershey, PA, USA
- OBJECTIVE: To investigate the predictive value of assays for HIV, p24 antigen (Ag), p24 antibody (ab) and gp120 ab compared to T4 cell counts in a cohort of 87 hemophiliacs with an actuarial cumulative AIDS incidence of 26% (+/- 7% SE) 8 years after ab seroconversion. METHODS: Ag was measured by the Abbott EIA, p24 an
- Chicago/Boston cohorts study: alpha p24/gp41 antibody response at HIV seroconversion.
- Int Conf AIDS. 1989 Jun 4-9;5:363 (abstract no. W.B.P.71). Unique Identifier : AIDSLINE ICA5/00179989
- Blaauw BB; Allen R; Falk L; Mayer K; Dawson G; Saltzman S; Rush-Presbyterian-St. Luke's Med Ctr Chicago, IL, USA
- Prognostic value of p24 Ag in HIV+ individuals is well established and recent studies have demonstrated that decline of alpha p24 may precede antigenemia by several years. We have reported previously use of alpha p24 for staging HIV+ individuals in the Chicago/Boston cohorts. Because of emerging relevance and prognost
- Predictive value of CD4+ numbers, levels of neopterin and beta-2-microglobulin and risk of developing Pneumocystis carinii pneumonia.
- Int Conf AIDS. 1989 Jun 4-9;5:363 (abstract no. W.B.P.72). Unique Identifier : AIDSLINE ICA5/00180089
- Weber R; Bruhwiler J; Ledergerber B; Vogt M; Fierz W; Luthy R; Department of Medicine, University Hospital, Zurich, Switzerland
- Primary prophylaxis of Pneumocystis carinii pneumonia (Pcp), the most frequent life threatening complication in AIDS, is not generally recommended, because the duration of asymptomatic HIV-infection is variable. Predictive indices are required to improve decision making regarding primary prophylaxis. OBJECTIVE: To det
- Human immunodeficiency virus (HIV) IgA serum antibodies in a longitudinal study of HIV infection and subsequent progression of the disease in homosexual men.
- Int Conf AIDS. 1989 Jun 4-9;5:364 (abstract no. W.B.P.73). Unique Identifier : AIDSLINE ICA5/00180189
- Levy E; Margalith M; Sarov B; Sarov I; Rinaldo C; Saah A; Faculty of Health Sciences, Ben-Gurion University of the Negev,; Beer Sheva, Israel
- OBJECTIVE: To determine the value of serum specific HIV IgA antibodies as a predictor of the progression of HIV infection. METHODS: A sensitive solid phase, enzyme linked immunosorbent assay (ELISA) has been adapted. Microplates coated with a mixture of 4 peptides which correspond to the serological active epitopes of
- T-cell subset, B2 microglobulin, and neopterin levels in Edinburgh haemophiliacs.
- Int Conf AIDS. 1989 Jun 4-9;5:364 (abstract no. W.B.P.74). Unique Identifier : AIDSLINE ICA5/00180289
- Cuthbert RJ; Ludlam CA; Beatson D; Steel CM; Dept. of Haematology, Royal Infirmary of Edinburgh, Scotland
- OBJECTIVE: To assess the value of B2 microglobulin, neopterin and T-cell subset estimations in predicting clinical progression to serious HIV disease in a cohort of haemophiliacs. METHODS: Longitudinal study of 18 HIV seropositive haemophiliacs since seroconversion in 1984, following exposure to a batch of HIV-contami
- IFN-alpha production, correlation with circulating IFN-alpha antigenemia P 24 and serological profile in HIV infected patients at different clinical stages.
- Int Conf AIDS. 1989 Jun 4-9;5:364 (abstract no. W.B.P.75). Unique Identifier : AIDSLINE ICA5/00180389
- Ruffault A; Genetet N; Michelet C; Guisthau O; Cartier F; Fauconnier B; Lab. Virologie, CHU, Rennes-France
- The aim of this work was to investigate the interferon system, both stimulated and circulating IFN-alpha and to correlate these markers to antigenemia P 24 and decline or lack of antibodies to Gag (P 18 - P 24 - P 55) and or to Pol (P 34 - P 68) antigens, in an attempt to predict the evolution and risk for opportunist
- Comparison of activation markers for progression to AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:364 (abstract no. W.B.P.76). Unique Identifier : AIDSLINE ICA5/00180489
- Di Franco MJ; Berger C; Friedman-Kien A; Edelson R; McLane M; Marlink R; Harvard School of Public Health, Boston, MA, USA
- OBJECTIVE: To assess progression to AIDS using markers of immune activation. METHODS: 60 gay men had serum neopterin (NEOP), a marker of macrophage activation, and beta2 microglobulin (BETA2) measured with a subset of men assessed for T4/T8 and BE2, a T4 cell antigen elevated in ATL, CTCL and AIDS. RESULTS: NEOP and B
- Forecasting individual rates of progression from ARC to AIDS using routine clinical laboratory tests.
- Int Conf AIDS. 1989 Jun 4-9;5:364 (abstract no. W.B.P.77). Unique Identifier : AIDSLINE ICA5/00180589
- Kvitash VI; Schmidt RM; Center for Preventive Medicine and Health Research, San Francisco; State University, San Francisco, California, USA
- OBJECTIVE: To develop a diagnostic procedure which definitively predicts the rate of progression of an individual with ARC to clinical AIDS. METHODS: In a prospective study of 30 ARC patients 6 immunological and 7 metabolic parameters were analyzed by Immuno-Balascopy (IBa), an artificial intelligence system for cogni
- Increased beta 2-microglobulin concentrations in children with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:364 (abstract no. W.B.P.78). Unique Identifier : AIDSLINE ICA5/00180689
- Chan M; Josephs S; Morales A; Campos JM; Rifai N; Children's Hospital National Medical Center and The George; Washington University School of Medicine, Washington, DC, USA
- OBJECTIVE: To determine whether serum beta2-microglobulin (beta2m) concentrations can be a sensitive marker for HIV infection in children, particularly infants, born to HIV-infected mothers. METHODS: beta2m is measured using an immunoturbidimetric procedure. RESULTS: Sera from 35 patients were tested in this study. Ni
- Neopterin as predictive marker for disease progression in human immunodeficiency virus-1 infection.
- Int Conf AIDS. 1989 Jun 4-9;5:365 (abstract no. W.B.P.79). Unique Identifier : AIDSLINE ICA5/00180789
- Fuchs D; Spira TJ; Hausen A; Reibnegger G; Werner ER; Wachter H; University of Innsbruck and Ludwig Boltzmann Institute of; AIDS-Research, A-6020 Innsbruck, Austria
- OBJECTIVE: The value of urinary neopterin levels for disease progression was determined in HIV-1 infected patients. METHOD: 68 HIV-1 seropositive homosexuals with lymphadenopathy syndrome were tested for urinary neopterin and T-cell subsets in 1982/83. Their AIDS incidence rate was evaluated in May 1988. RESULTS: Over
- Persistence of good E-CR1 activity relates to non-progression of immune dysfunction in HIV positive individuals.
- Int Conf AIDS. 1989 Jun 4-9;5:365 (abstract no. W.B.P.80). Unique Identifier : AIDSLINE ICA5/00180889
- Lange M; Inada Y; Buimovici-Klein E; Ramey W; Cooper LZ; Grieco MH; St. Luke's-Roosevelt Hospital Center, Columbia University, New; York, New York, USA
- OBJECTIVE: The Erythrocyte complement 3B receptor (E-CR1) is postulated to provide a cofactor role for the factor I in the inactivation of Complement 3B (C3B) thereby preventing (i) amplification of the positive alternate complement loop and (ii) activation of the terminal complement cascade. In addition E-CR1 binds c
- Serum B2M in intravenous drug abusers with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:365 (abstract no. W.B.P.81). Unique Identifier : AIDSLINE ICA5/00180989
- Cooper EH; Forbes MA; Sutherland S; MacManus TJ; University of Leeds, Leeds, England
- OBJECTIVE: To determine whether IVDA influences serum beta-2-microglobulin distribution in HIV infection that may interfere with its interpretation as a prognostic index to determine the risk of progressing to AIDS. METHODS: Sera referred to the PHLS were measured by the Pharmacia B2M-RIA. RESULTS: The patients were s
- [1-14C] arachidonic acid release from human CD4+ monocytic U 937 and CD4+ T-lymphocytic CEM cell lines in the early stage of HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:365 (abstract no. W.B.P.82). Unique Identifier : AIDSLINE ICA5/00181089
- Dray F; Renard CA; Guetard D; Errasfa M; Vulliez-Le Normand B; Massiet du Biest B; Montagnier L; U.207 INSERM, URIA; Paris, France
- OBJECTIVE/METHODS: Phospholipids (PLs) of cellular membranes require an appropriate percentage of unsaturated fatty acids in the various lipids to maintain their structural and functional characters. This percentage is mainly influenced by phospholipase activities (PLA). Such PLA should be studied in the different cel
- Evaluation of beta-2-microglobulin and neopterin as prognostic markers in HIV disease.
- Int Conf AIDS. 1989 Jun 4-9;5:365 (abstract no. W.B.P.83). Unique Identifier : AIDSLINE ICA5/00181189
- Sandstrom E; Karlsson A; Holmberg V; The Gay Mens Health Clinic, Sodersjukhuset, Stockholm, Sweden
- OBJECTIVE: A study was designed to elucidate the usefulness of Beta-2-microglobulin (beta2m) and Neopterin in predicting disease progression to ARC and AIDS. METHODS: A total of 1198 frozen serum samples, collected during 1983-88 in Stockholm from 185 homo-and bisexual men who were or turned HIV seropositive, were ana
- Increased proliferation of oral epithelial cells in HIV-infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:365 (abstract no. W.B.P.84). Unique Identifier : AIDSLINE ICA5/00181289
- Langford A; Kunze R; Ehm I; Pohle HD; Reichart P; Free University, Rudolf-Virchow Univ., D-1 Berlin 65, FRG
- OBJECTIVE: To determine the proliferation of oral epithelium in patients in different clinical stages of HIV infection. MATERIAL AND METHODS: Mouth washes (10 ml PBS) of 20 HIV seropositive patients (asympt. n=5, ARC: n=7, AIDS n=8) and of 20 HIV seronegative persons were obtained under standard conditions. The oral e
- Measurement of beta2-microglobulin (beta2M) by rate immunonephelometric assay in blood from AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:366 (abstract no. W.B.P.85). Unique Identifier : AIDSLINE ICA5/00181389
- Khayam-Bashi H; Johnson N; Chen K; Wilber J; Clinical Labs, SF General Hospital and Dept. Lab Med., UCSF, San; Francisco, CA, USA
- OBJECTIVE: beta2M content of blood, CD4 T-cell count, hemoglobin and social and behavioral risk factors have been proposed as prognostic indicators in AIDS/ARC patients. We developed a method to measure beta2M by immunonephelometry (INA). METHODS: We used the Beckman ICS nephelometer and commercially available anti-be
- The classification of HIV disease: correlation of beta-2-microglobulin (B-2-M) and erythrocyte sedimentation rate (ESR).
- Int Conf AIDS. 1989 Jun 4-9;5:366 (abstract no. W.B.P.86). Unique Identifier : AIDSLINE ICA5/00181489
- Kilborn J; Fisher EJ; Markowitz N; Saravolatz LD; Henry Ford Hospital, Detroit, Michigan, USA
- OBJECTIVE: To identify the role of beta-2-microglobulin, erythrocyte sedimentation rate, and hemoglobin (Hb) as predictive indicators of CDC-HIV stages. METHODS: At the time of initial medical assessment, 70 HIV(+) men were classified according to CDC clinical stage and had serum B-2-M, ESR, Hb and CD2, CD4, and CD8 T
- Quest for prognostic markers in HIV infected haemophiliac children.
- Int Conf AIDS. 1989 Jun 4-9;5:366 (abstract no. W.B.P.87). Unique Identifier : AIDSLINE ICA5/00181589
- Skidmore S; Williams MD; Mawson SJ; Hill FG; Regional Virus Laboratory, East Birmingham Hospital, Birmingham,; UK
- OBJECTIVE: To assess the predictive value of laboratory markers in progression of HIV infection in a cohort of haemophiliac boys. METHODS: Assays for anti-HIV, anti-p24 antibody, p24-antigen, alpha-interferon, neopterin and B2-microglobulin were bought in kit form and carried out according to the manufacturer s instru
- Routine laboratory tests which correlate with HIV-1 infection prior to onset of AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:366 (abstract no. W.B.P.88). Unique Identifier : AIDSLINE ICA5/00181689
- Wallace JI; Beatrice S; Sacks HS; Foundation for Research on Sexually Transmitted Diseases, NY, NY,; USA
- OBJECTIVE: To identify routine laboratory tests whose results can correlate with HIV-1 infection in asymptomatic people. METHODS: A group of 110 apparently healthy, formerly drug addicted women was evaluated during 1983-1985. The relationship of routine laboratory tests to anti-HIV-1 antibody presence was evaluated by
- Neopterin is a relevant diagnostic marker in HIV-infection.
- Int Conf AIDS. 1989 Jun 4-9;5:366 (abstract no. W.B.P.89). Unique Identifier : AIDSLINE ICA5/00181789
- Reisinger E; Kern P; Schwander S; Dorlemann A; Ernst M; Berzow D; Plettenberg A; Flad HD; Dietrich M; Clin. Dptm. Bernhard-Nocht-Inst. for Tropical Med., Hamburg, FRG
- OBJECTIVE: Neopterin is produced by gamma-interferon stimulated macrophages. We report on the correlation of serum-neopterin with the course of HIV-infection during a prospective randomized double blind treatment study. METHODS: 54 patients were examined in 6-weeks intervals and the neopterin levels were correlated wi
- The use of serum oligoclonal immunoglobulins to monitor the course of HIV-infection.
- Int Conf AIDS. 1989 Jun 4-9;5:366 (abstract no. W.B.P.90). Unique Identifier : AIDSLINE ICA5/00181889
- Papadopoulos N; Costello R; National Institutes of Health, Bethesda, Maryland, USA
- OBJECTIVE: To use oligoclonal bands as markers to follow the course of HIV-infection. METHODS: The increased sensitivity of our zone electrophoresis technique to determine serum proteins demonstrates discrete oligoclonal immunoglobulin bands (OIB) within an intense diffuse gamma-globulin zone. Originally OIB were foun
- CSF neopterin in HIV-1 infection and as a function of AIDS dementia complex (ADC) severity.
- Int Conf AIDS. 1989 Jun 4-9;5:367 (abstract no. W.B.P.91). Unique Identifier : AIDSLINE ICA5/00181989
- Brew BJ; Bhalla R; Schwartz M; Price RW; Memorial Sloan-Kettering Cancer Center, New York, NY, USA
- OBJECTIVES: To determine the clinical significance of elevated concentrations of neopterin in the cerebrospinal fluid (CSF) of HIV-infected individuals and assess the value of CSF neopterin as a marker of ADC. METHODS: 50 samples of CSF and serum from 44 neurologically symptomatic patients at various stages of HIV inf
- Predictive value of neopterin, beta2-microglobulin and thymidinkinase in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:367 (abstract no. W.B.P.92). Unique Identifier : AIDSLINE ICA5/00182089
- Goebel FD; Matuschke A; Heinrich B; Fuessl HS; Bogner JR; Med. Poliklinik Universitat Munchen, FRG
- OBJECTIVE: To determine the predictive value of beta2 Microglobulin (beta2), Neopterin (Npt) and Thymidinkinase (Tk) in patients (pts) with or without progression of HIV disease. METHODS: 60 HIV-AB pos. pts in 4 groups with different clinical deterioration within 2 years (group I: progression WR1 to WR 6; II: WR1 to W
- Efficient screening for HIV 1- and HIV 2-antibodies with a 3rd generation assay.
- Int Conf AIDS. 1989 Jun 4-9;5:367 (abstract no. W.B.P.93). Unique Identifier : AIDSLINE ICA5/00182189
- Krupka U; Brust S; Julien T; Behringwerke AG, 3550 Marburg, FRG
- OBJECTIVE: To describe the features of a new ELISA (Enzygnost-Anti-HIV 1 + 2) based on synthetic peptides corresponding to env-proteins of HIV 1 and HIV 2. METHODS: 50 mul undiluted specimen are added to 50 mul diluent into each well of microtitration plates coated with a cocktail of 4 synthetic peptides. After an inc
- The use of the N-terminal portion of the transmembrane proteins for the early detection and discrimination of HIV 1 and HIV 2 infection.
- Int Conf AIDS. 1989 Jun 4-9;5:367 (abstract no. W.B.P.94). Unique Identifier : AIDSLINE ICA5/00182289
- Vornhagen R; Hinderer W; Nebel-Schickel H; Motz M; Soutschek-Bauer E; Walz A; Wolf H; Sonneborn HH; Biotest AG, Research Dept., Offenbach, FRG
- OBJECTIVE: To determine the usefulness of the transmembrane proteins for early discrimination of HIV 1 and HIV 2 infections. METHODS: A DNA-fragment coding for the N-terminal region of the transmembrane protein of HIV 1 and the corresponding sequence of HIV 2 which has been chemically synthesized were cloned and expre
- A semiautomated dot blot immunoassay for the confirmation of HIV seropositivity.
- Int Conf AIDS. 1989 Jun 4-9;5:367 (abstract no. W.B.P.95). Unique Identifier : AIDSLINE ICA5/00182389
- Knigge KM; Braun B; Chan E; Kapsalis A; Schulze W; Stephens J; Abbott Laboratories, North Chicago, IL, USA
- OBJECTIVE: To develop an HIV confirmatory assay which is more sensitive and specific than Western blot. METHODS: Purified recombinant proteins of HIV-1 and HIV-2 are immobilized on nitrocellulose. The assay is conducted in a 35 C incubator automated for timed incubations, sample removal, washing, drying and reflectanc
- Improvement of anti-HIV-2 reactivity of Vironostika anti-HTLV-III.
- Int Conf AIDS. 1989 Jun 4-9;5:367 (abstract no. W.B.P.96). Unique Identifier : AIDSLINE ICA5/00182489
- Sprengers ED; Ten Kortenaar P; Hellings JA; Theunissen HJ; Ariens J; Sprang VR; Diagnostics Research Labs, Organon International B.V., P.O. Box; 20, 5340 BH, Oss, The Netherlands
- HIV-2 has been described as a second causative agent of AIDS. Therefore anti-HIV-screening assays should be fully sensitive to both anti-HIV-1 and anti-HIV-2 antibodies. The existing competitive anti-HIV-1 EIA s have a sensitivity of 28-51% for anti-HIV-2 sera; existing indirect EIA s have a sensitivity of 70-93% for
- Development of two diagnostic systems for HIV seroconversion using two recombinant antigens.
- Int Conf AIDS. 1989 Jun 4-9;5:368 (abstract no. W.B.P.97). Unique Identifier : AIDSLINE ICA5/00182589
- Benitez J; Novoa LI; Machado JA; Garcia J; Padron G; Herrera L; Center of Genetic Engineering and Biotechnology. C. Habana, Cuba
- OBJECTIVE: To develop two alternative diagnostic systems for HIV-antibodies detection using two recombinant antigens. METHODS: The recent development of second-generation tests based on simple and manual procedures for rapid diagnosis of HIV antibodies are said to be so reliable and easy to use, they could allow futur
- Cross reaction between HIV-1 and HIV-2 or double infection.
- Int Conf AIDS. 1989 Jun 4-9;5:368 (abstract no. W.B.P.98). Unique Identifier : AIDSLINE ICA5/00182689
- Schmidt BL; Gschnait F; Mayer F; Hutterer J; Banekowich F; Schulz TF; Dierich M; Department of Dermatology of the Hospital of Lainz, Vienna,; Austria; Ludwig Boltzmann Institute for Dermato-Venerological; Serodiagnosis, Vienna, Austria
- HIV-1 and HIV-2 viruses exhibit a high degree of sequence homology, in particular in the core proteins. Antibodies to HIV-2 core proteins might cross-react with HIV-1 and vice versa, whereas envelope proteins are antigenically distinct. Distinction between antibodies to HIV-1 and HIV-2 thus is usually attempted on the
- Evaluation of HIV-1 and HIV-2 ELISA based on synthetic peptides of gp41.
- Int Conf AIDS. 1989 Jun 4-9;5:368 (abstract no. W.B.P.99). Unique Identifier : AIDSLINE ICA5/00182789
- Kunz C; Heinz FX; Parkhede U; Institute of Virology, University of Vienna, Vienna, Austria
- OBJECTIVE: Assessment of peptide-based enzyme-immunoassays for the detection of antibodies against HIV. METHODS: Three different tests were used: an HIV-1 assay based on a peptide from gp41, an HIV-2 assay based on the corresponding peptide from gp36, and a combi-test which contains both the HIV-1 and the HIV-2 peptid
- [Aptitude of a rapid test for HIV1 and of aggatination tests for detecting anti-HIV2 antibodies in Senegal]
- Int Conf AIDS. 1989 Jun 4-9;5:368 (abstract no. W.B.P.100). Unique Identifier : AIDSLINE ICA5/00182889
- M'Boup S; Sankale JL; Kabeya CM; Diakhate L; Thiam D; Mitchell S; Bacterio-Virologie/Universite de Dakar, Senegal
- Contribution of synthetic peptides (SYP) to the serologic diagnosis of HIV-1 and HIV-2 reactivity.
- Int Conf AIDS. 1989 Jun 4-9;5:368 (abstract no. W.B.P.101). Unique Identifier : AIDSLINE ICA5/00182989
- Ercilla G; Barrera JM; Gil MP; Baylo A; Gatell JM; Castillo R; Blood Bank and Infectious Med. Dept. Hospital Clinic. Barcelona.; Spain
- OBJECTIVE: To determine the extent of HIV-2 infection in high risk populations and its relationship with HIV-1 infection. METHODS: HIV-1 and HIV-2 antibodies were studied in sera of 215 individuals at risk, 22 out of them showing an indeterminate HIV-1 Western blot, and 70 sera from West Africa people. Sera were scree
- Type specificity of the highly immunoreactive epitopes of HIV-1 and HIV-2.
- Int Conf AIDS. 1989 Jun 4-9;5:368 (abstract no. W.B.P.102). Unique Identifier : AIDSLINE ICA5/00183089
- Korkolainen M; Narvanen A; Kontio S; Rescaldani R; Visconti A; Huhtala ML; Labsystems Research Laboratories, Helsinki, Finland
- We have developed sensitive EIA s to detect human serum antibodies elicited against HIV-1 and HIV-2. EIA s are based on synthetic peptides derived from transmembrane proteins gp41 and gp34 respectively. These peptides share 30 % homology with each other. In our earlier studies we have compared the HIV-1 specific env p
- Evaluation of a new combined HIV1&2 IgG EIA based on synthetic peptides.
- Int Conf AIDS. 1989 Jun 4-9;5:369 (abstract no. W.B.P.103). Unique Identifier : AIDSLINE ICA5/00183189
- Seidl S; Blutenspendedienst Hessen, Frankfurt, West Germany
- OBJECTIVE: Recently a new type of retrovirus, HIV2, associated with AIDS was discovered. Although the majority of HIV2 infections are concentrated to West Africa it has also been detected in Europe. Anti-HIV screening might thus in a near future require simultaneous detection of antibodies to HIV1 and HIV2 respectivel
- Reliable differentiation between anti HIV-1 and anti HIV-2 antibodies using a competitive assay.
- Int Conf AIDS. 1989 Jun 4-9;5:369 (abstract no. W.B.P.104). Unique Identifier : AIDSLINE ICA5/00183289
- Meyer CG; Berzow D; Schmitz H; Bernhard-Nocht-Institut for Tropical Medicine, Hamburg, FRG
- OBJECTIVE: To clarify the question, if sera, reacting in both HIV-1 and HIV-2 test systems have to be assessed either to Human immunodeficiency virus type I or type II. METHODS: F(ab)2 fragments were prepared from 6 crossreacting sera, purified by gel and affinity chromatography, pooled, and incubated simultaneously w
- Line immunoassay for the simultaneous detection of antibodies to HIV-1 and HIV-2 in human sera.
- Int Conf AIDS. 1989 Jun 4-9;5:369 (abstract no. W.B.P.105). Unique Identifier : AIDSLINE ICA5/00183389
- Pollet DE; Saman E; van der Borght B; Vercauteren G; Buscher P; van der Groen G; Innogenetics NV, Antwerp, Belgium
- OBJECTIVE: Evaluation of recombinant proteins and chemically synthesized peptides in a line immunoassay technique (LIA) on their sensitivity and specificity compared to Western blot, for the detection of antibodies to HIV-1 and HIV-2. METHODS: In the LIA technique gag (p24 and p17), and pol (endonuclease) recombinant
- Efficacy of Abbott recombinant HIV-1/HIV-2 EIA for early detection of HIV-2 and/or HIV-1 seroconversion.
- Int Conf AIDS. 1989 Jun 4-9;5:369 (abstract no. W.B.P.106). Unique Identifier : AIDSLINE ICA5/00183489
- Ferchal F; Agbalika F; Honderlick P; Barateau V; Perol Y; Laboratoire de bacteriologie/virologie, Hopital St-Louis,; Paris, France
- The greatest difficulty in HIV diagnosis in Europe is to have at one s disposal an ELISA test sensitive enough to detect low levels of HIV-2 as well as HIV-1 antibodies. We determined the performance characteristics of Abbott Recombinant HIV-1/HIV-2 EIA by studying sequential sera from one HIV-2 and seven HIV-1 seroco
- Detection of HIV-1 and HIV-2 antibodies in African sera by the ENV-9 (gp120-HIV1) recombinant protein.
- Int Conf AIDS. 1989 Jun 4-9;5:369 (abstract no. W.B.P.107). Unique Identifier : AIDSLINE ICA5/00183589
- Peeters M; Delaporte E; Honore C; Bedjabaga L; Ossari S; Brun-Vezinet F; Centre International de Recherches Medicales, BP 769,; Franceville, Gabon
- OBJECTIVE: To evaluate the performance of the ENV-9 recombinant protein in an ELISA test and a rapid test (HIV-check) in detecting antibodies to HIV2. METHODS: A panel of 49 sera, positive for HIV2 antibodies by WB and/or RIPA (presence of gp36 and/or gp140) were tested with the ENV-9 recombinant ELISA (Dupont de Nemo
- [Performances obtained with 11 ELISA HIV-1 and/or HIV-2 kits, using whole viruses, recombinant antigens or synthetic peptides and African blood specimens]
- Int Conf AIDS. 1989 Jun 4-9;5:369 (abstract no. W.B.P.108). Unique Identifier : AIDSLINE ICA5/00183689
- Leonard G; Gershy-Damet GM; Sangare A; Verdier M; Ranger S; Denis F; Department Virologie, CHU Limoges, France
- Sensitivity and discriminatory value of synthetic peptide assays for HIV-1 and 2 infections.
- Int Conf AIDS. 1989 Jun 4-9;5:370 (abstract no. W.B.P.109). Unique Identifier : AIDSLINE ICA5/00183789
- Lange J; Vahlne A; Boucher C; Barin F; Parkhede U; Goudsmit J; Academic Medical Centre, University of Amsterdam, Netherlands
- OBJECTIVE: To evaluate a combined HIV-1 and 2 enzyme immunoassay. METHODS: Microtiter plates were coated with: a) a 23 mer synthetic peptide, presenting a continuous epitope of the HIV-1 transmembrane protein (env-1), or b) a 24 mer peptide, presenting a homologous region of the HIV-2 transmembrane protein (env-2), orr
- Comparative performance of cyclic versus linear peptides in an ELISA for HIV-1- and HIV-2-specific antibodies.
- Int Conf AIDS. 1989 Jun 4-9;5:370 (abstract no. W.B.P.110). Unique Identifier : AIDSLINE ICA5/00183889
- Lacroix M; Chalifour R; Stern MD; Dionne G; IAF BioChem International Inc., Laval, Quebec, Canada, H7V 1B7
- OBJECTIVE: Report on the superiority of cyclic peptides of the transmembrane glycoproteins over their linear counterparts as antigens in an ELISA for the highly sensitive detection of antibodies to HIV-1 and to HIV-2. METHODS: Peptides covering an immunodominant region of HIV-1 and of HIV-2 transmembrane glycoproteinsr
- A peptide-based microtiter ELISA kit for the detection of antibodies to HIV-1 and to HIV-2.
- Int Conf AIDS. 1989 Jun 4-9;5:370 (abstract no. W.B.P.111). Unique Identifier : AIDSLINE ICA5/00183989
- Lacroix M; Penney CL; Dwyer RJ; Stern MD; Bellini F; Dionne G; Tsoukas C; IAF BioChem International Inc., Montreal, Can., H7V 1B7
- Although many assays for HIV-1 antibodies are now on the market, they do not always perform as well as claimed by the manufacturers. Clearly, there is an urgent need for a more specific and more sensitive HIV antibody test. Our assay uses synthetic peptides mimicking highly conserved and immunodominant epitopes of gp4r
- Serologic classification of US patient sera dually reactive for HIV-1 and HIV-2.
- Int Conf AIDS. 1989 Jun 4-9;5:370 (abstract no. W.B.P.112). Unique Identifier : AIDSLINE ICA5/00184089
- Pau CP; George R; Wolinsky S; Schochetman G; Centers for Disease Control, Atlanta, GA, USA
- OBJECTIVE: To characterize and classify sera of US origin, which are dually reactive for HIV-1 and HIV-2 by EIA. METHODS: Forty-one sera from the Multi-center AIDS Cohort Study that were dually reactive by ELISA were further tested for HIV-1 and HIV-2 antibodies by Western blot (Genetic Systems and DuPont) and by virar
- Evaluation of HIV-1 and HIV-2 peptide ELISA tests in sera from Abidjan, Cote d'Ivoire.
- Int Conf AIDS. 1989 Jun 4-9;5:370 (abstract no. W.B.P.113). Unique Identifier : AIDSLINE ICA5/00184189
- Heyward W; Rayfield M; Krebs J; De Cock K; Odehouri K; Schochetman G; Centers for Disease Control, Atlanta, GA, USA
- OBJECTIVE: To evaluate HIV-1 and HIV-2 peptide ELISA tests in a population with both HIV-1 and HIV-2 infections. METHODS: Sera from 957 persons (hospitalized and non-hospitalized) from Abidjan were tested for HIV-1 and HIV-2 by whole virus lysate ELISA (VEIA), type-specific peptide ELISA (PEIA) against the immunodominr
- Evaluation of Pharmacia HIV 1&2 Combi IgG EIA, a synthetic peptide EIA.
- Int Conf AIDS. 1989 Jun 4-9;5:370 (abstract no. W.B.P.114). Unique Identifier : AIDSLINE ICA5/00184289
- Grillner L; Parkhede U; Persson PO; Sandstrom E; Karolinska Institute, Stockholm, Sweden
- OBJECTIVE: To evaluate a new anti-HIV EIA, HIV 1&2 Combi IgG (Pharmacia Diagnostics AB). In the test synthetic peptides corresponding to parts of the transmembraneous protein of HIV-1 and HIV-2 are used as antigens. METHODS: 10 402 consecutive blood donations were tested for HIV antibodies by HIV 1&2 Combi, Vir
- Detection of HIV-1 antibodies using synthetic peptides.
- Int Conf AIDS. 1989 Jun 4-9;5:371 (abstract no. W.B.P.115). Unique Identifier : AIDSLINE ICA5/00184389
- Mendes N; Peixinho Z; Hernandez H; Longo I; Nakaie C; Paiva A; Escola Paulista de Medicina, Sao Paulo, Brazil
- OBJECTIVE: To standardize an indirect immunoenzymatic assay for the detection of HIV-1 antibodies using synthetic peptides. METHODS: Two synthetic peptides corresponding to a segment of gp41 described by Wang (PNAS 83:6159,1986) and Gnann et al. (Science 237:1346, 1987), respectively with 21 (RILAVERYLKDQQLLGIWGCS) an
- Detection of anti-HIV, core and envelope IgG, in HIV-infected and tropical diseased from Brazil.
- Int Conf AIDS. 1989 Jun 4-9;5:371 (abstract no. W.B.P.116). Unique Identifier : AIDSLINE ICA5/00184489
- Timmerman A; Hammerschlak N; Hospital Albert Einstein, Sao Paulo, Brazil
- OBJECTIVE: Anti-HIV assays based on synthetic peptides and recombinant produced antigens have been developed in Europe and US. These tests need, however, also to be documented in countries with other patterns of infections and possibly variations of HIV. METHODS: We have used a test system based on synthetic peptides
- Comparison of Cambridge Biosciences Recombigen HIV Latex Agglutination Assay with three commercial ELISA assays.
- Int Conf AIDS. 1989 Jun 4-9;5:371 (abstract no. W.B.P.117). Unique Identifier : AIDSLINE ICA5/00184589
- Tamburini M; Downing RG; Biryahwaho B; WHO/AIDS Control Programme, Entebbe - Uganda
- OBJECTIVE: ELISA screening facilities are difficult to maintain in small hospital laboratories. We therefore decided to evaluate a rapid Latex Agglutination Assay for use in Uganda . METHODS: Manufacturers protocols were followed carefully. We gratefully acknowledge the gift of Late
- The determination of additional serological markers concerning HIV-infection using recombinant viral antigens of all HIV 1 reading frames.
- Int Conf AIDS. 1989 Jun 4-9;5:371 (abstract no. W.B.P.118). Unique Identifier : AIDSLINE ICA5/00184689
- Vornhagen R; Motz M; Soutschek-Bauer E; Pichler W; Siegl G; Hinderer W; Wolf H; Sonneborn HH; BIOTEST AG, Research Dept., Offenbach, FRG
- OBJECTIVE: The evaluation of additional serological markers for prognostic purposes using recombinant viral antigens of all HIV 1-reading frames. METHODS: DNA-Fragments of all HIV 1-reading frames coding for the major structural antigens and parts of them as well as the in vivo weakly expressed regulative proteins hav
- Anti-HTLV-I tax ELISA for detection of infection in standard HTLV-I ELISA negative intravenous drug users (IVDUs).
- Int Conf AIDS. 1989 Jun 4-9;5:371 (abstract no. W.B.P.119). Unique Identifier : AIDSLINE ICA5/00184789
- Glaser JB; Poiesz BJ; Sliwkowski M; Simpkins H; Sninsky JJ; Ehrlich GD; Richmond Memorial & Staten Island Hospitals, SI, NY, USA
- OBJECTIVE: To assess the sensitivity of the standard ELISA for detection of HTLV-I infection. METHODS: Serum was obtained from 235 IVDUs from 5/1/86 to 8/15/87 and tested by HTLV-I ELISA. Since the HTLV-I tax protein product is not packaged in the mature virion, a variety of assays to detect this antigen were prepared
- Clinical evaluation of Testpack HIV-1/HIV-2 rapid assay for the detection of antibody to HIV-1 and HIV-2 using recombinant dNA derived HIV-1 and HIV-2 proteins.
- Int Conf AIDS. 1989 Jun 4-9;5:371 (abstract no. W.B.P.120). Unique Identifier : AIDSLINE ICA5/00184889
- Alcalde X; Weiss R; Staller J; Prozorovsky L; Knigge K; Pennington R; Abbott Laboratories, North Chicago, IL, USA
- OBJECTIVE: The Testpack HIV-1/HIV-2 rapid enzyme immunoassay for the detection of antibody to two Human Immunodeficiency Viruses (HIV-1 and HIV-) has been evaluated in clinical trials at four European sites. METHODS: To date, these sites have tested a total of 2455 specimens by both the Testpack HIV-1/HIV-2 assay and
- Testpack HIV: rapid assays capable of detecting antibodies to HIV present in serum, plasma, and whole blood.
- Int Conf AIDS. 1989 Jun 4-9;5:372 (abstract no. W.B.P.121). Unique Identifier : AIDSLINE ICA5/00184989
- Weiss RA; Pennington RM; Knigge KM; Staller JM; Prozorovsky LA; Martorano A; Abbott Laboratories, North Chicago, Il. and Howard Brown Memorial; Clinic, Chicago, IL, USA
- OBJECTIVE: To develop rapid, visual immunoassays to detect antibodies to Human Immunodeficiency Viruses 1 and 2. These assays require minimal sample preparation, minimal technical expertise, no sophisticated equipment and provide easily interpretable results. METHODS: These tests utilize full length recombinant antige
- Unique immunoreactivity of a normal human serum with recombinant HTLV-I env gene products.
- Int Conf AIDS. 1989 Jun 4-9;5:372 (abstract no. W.B.P.122). Unique Identifier : AIDSLINE ICA5/00185089
- Shih J; Genesca J; Frenkl T; Terry R; Buonagurio D; Longiaru M; Dept. Transfusion Medicine, NIH, Bethesda, MD, USA
- OBJECTIVE: To assess an anti-HTLV-I ELISA test based on recombinant products and to identify the specificity and significance of the immunoreactivity between the serum of a normal blood donor and recombinant HTLV-I envelope proteins. METHODS: Clones containing different regions of HTLV-I genome were constructed and re
- Improved in situ detection of HIV nucleic acid with fluorescent probes and laser excitation.
- Int Conf AIDS. 1989 Jun 4-9;5:372 (abstract no. W.B.P.123). Unique Identifier : AIDSLINE ICA5/00185189
- Hart L; Donovan RM; Bradey PF; Peterson WR; Goldstein E; University of California, Davis, California, USA
- OBJECTIVE: To develop more sensitive instrumentation to detect and quantitate HIV infected cells in culture and in clinical specimens using nonradioactive in situ hybridization. METHODS: Acetylaminofluorene (AAF) HIV DNA probes were made and reacted by in situ hybridization with HIV infected CEM cell lines. The AAF-la
- Detection of HIV in hematopoietic cells from patients with AIDS and AIDS-related complex (ARC).
- Int Conf AIDS. 1989 Jun 4-9;5:372 (abstract no. W.B.P.124). Unique Identifier : AIDSLINE ICA5/00185289
- Sun NC; Hsu MY; Conrad A; Shapshak P; Beall G; Imagawa D; Harbor-UCLA Medical Center, Torrance, CA, USA
- OBJECTIVE: To test the hypothesis that hematologic abnormalities in patients (pts) with ARC and AIDS were related to direct and persistent HIV infection of the hematopoietic precursors in the bone marrows. METHOD: We used (3)H-labelled cDNA probe and in situ hybridization (ISH) method to detect the presence of HIV nuc
- Seroconversion followed by recombinant- and synthetic peptide based anti-HIV analysis.
- Int Conf AIDS. 1989 Jun 4-9;5:372 (abstract no. W.B.P.125). Unique Identifier : AIDSLINE ICA5/00185389
- Lauritzen E; Petersen C; Vejlsgaard GL; Lindhardt BO; Black F; Horal P; Statens Seruminstitut, Copenhagen, Denmark
- OBJECTIVE: To define the sensitivity of recombinant- and synthetic peptide based anti-HIV ELISA tests. METHODS: A total of 290 sera, which were collected during the weeks and months of seroconversion, from 75 patients were studied with anti-HIV tests. The 28 patients had acute symptoms, while 47 patients did not repor
- HIV-1 pol synthetic peptides.
- Int Conf AIDS. 1989 Jun 4-9;5:372 (abstract no. W.B.P.126). Unique Identifier : AIDSLINE ICA5/00185489
- Sprengers ED; Schalken JJ; Hellings JA; Sprang RV; Diagnostics Research Labs, Organon International B.V., P.O. BOX; 20, 5340 BH, Oss, The Netherlands
- The HIV-1 POL amino-acid sequence was analysed for antigenic epitopes by epitope-prediction programmes such as Hopp and Woods. Of the epitopes predicted by this method 14, partially overlapping, peptides were synthesized by solid phase methodology. The peptides were coated to microelisa plates and analysed for reactiv
- Investigation of recombigen (TM) HIV EIA (Cambridge BioScience Corporation).
- Int Conf AIDS. 1989 Jun 4-9;5:373 (abstract no. W.B.P.127). Unique Identifier : AIDSLINE ICA5/00185589
- Major C; McLaughlin B; O'Shaughnessy MV; Ontario Ministry of Health, Toronto
- OBJECTIVE: A new, indirect EIA test employing recombinant polypeptides gp41 and 120 (env) and p24 (gag) expressed in E. coli, for the detection of antibodies to HIV was investigated. METHODS: A panel of 875 sera was selected to include: 55 seroconversions (134 sera); 89 confirmed reactive sera, including 10 weakly-rea
- Production and characterization of monoclonal antibodies against HTLV-I core proteins.
- Int Conf AIDS. 1989 Jun 4-9;5:373 (abstract no. W.B.P.128). Unique Identifier : AIDSLINE ICA5/00185689
- Yoshihara P; Williams S; Benelli M; Majewski S; Logan D; Goldstein AS; Epitope, Inc., Beaverton, Oregon, USA
- OBJECTIVE: To identify and characterize core protein fragments on HTLV-I Western blot strips utilizing anti-core protein monoclonal antibodies (MAb). METHODS: Balb/c mice were immunized utilizing HTLV-I viral lysate as immunogen. Hybridoma cells were cloned which produced MAb reactive with HTLV-I core protein as analy
- Early seroconversion detected by anti-HIV recombinant ELISA.
- Int Conf AIDS. 1989 Jun 4-9;5:373 (abstract no. W.B.P.129). Unique Identifier : AIDSLINE ICA5/00185789
- Samuelson A; Sydow M; Grillner L; Gaines H; Forsgren M; Strannegard O; Central Microbiological Laboratory of Stockholm County Council
- OBJECTIVE: To study the usefulness of the Wellcozyme HIV recombinant test for the diagnosis of HIV infection and, in particular, the ability of the test to detect early seroconversion. METHODS: 526 sera comprising a panel including 120 confirmed HIV-positive, 30 Western blot (WB)-negative sera with ambiguous results b
- Detection of anti-tax antibody in HTLV-I Western blots.
- Int Conf AIDS. 1989 Jun 4-9;5:373 (abstract no. W.B.P.130). Unique Identifier : AIDSLINE ICA5/00185889
- Connelly M; Tadler M; O'Connell C; E.I. DuPont, Medical Products Department, Wilmington, DE, USA
- OBJECTIVE: To determine whether antibody to the TAX gene product of HTLV-I may be detected by using viral lysate based Western blots (WB). METHODS: HTLV-I WB strips were obtained from Biotech Research Laboratory and Diagnostics Biotechnology Limited. Samples were incubated as per WB kit instructions. Recombinant p40X
- Detection of HIV--1 antibodies in immunometric elisa based on labeled synthetic peptide.
- Int Conf AIDS. 1989 Jun 4-9;5:373 (abstract no. W.B.P.131). Unique Identifier : AIDSLINE ICA5/00185989
- Kozhich AT; Ivanov VS; Suvorova ZK; Shemyakin Institute of Bioorganic Chemistry, Moscow, USSR
- OBJECTIVE: To compare synthetic-peptide immunometric ELISA and standard ELISA with labeled immunoglobulins. METHODS: Both techniques utilize microtiter plates coated with synthetic peptide. Bound antibodies are detected either by the same but labeled peptide (immunometric format), or labeled anti-immunoglobulins, or p
- Vironstika HIV core assay: an anti-p24/p55 specific test using viral antigen and monoclonal antibodies.
- Int Conf AIDS. 1989 Jun 4-9;5:373 (abstract no. W.B.P.132). Unique Identifier : AIDSLINE ICA5/00186089
- Schalken JJ; Keur W; Jacobs A; Vodegel P; Hellings JA; Organon Int., Diagnostics Res. Labs., Oss, The Netherlands
- OBJECTIVE: Progression in seropositive individuals to AIDS is strongly associated with declining or absent levels of anti-p24 antibodies, and high levels of antigen. Therefore, it was of interest to develop an assay specific for anti-p24 antibodies. METHODS: Vironostika HIV CORE is based on the inhibition principle us
- A screening assay for antibodies to HIV-1 using recombinant antigens.
- Int Conf AIDS. 1989 Jun 4-9;5:374 (abstract no. W.B.P.133). Unique Identifier : AIDSLINE ICA5/00186189
- Wu P; Keehn DR; Liu DJ; Pawlowski JM; Roser MA; Staser JA; Abbott Laboratories, North Chicago, Illinois, USA
- OBJECTIVE: To develop a screening enzyme immunoassay (EIA) for antibodies to HIV-1 using recombinant antigens which allows detection of both IgG and IgM. This assay is capable of reducing the window between antigenemia and seroconversion. METHODS: The recombinant gag (rp24) protein includes the full sequence of p24. T
- Characterization of full-length recombinant HIV-1 p41 and p24 for use in the improved abbott HIV-1 enzyme immunoassay.
- Int Conf AIDS. 1989 Jun 4-9;5:374 (abstract no. w.B.P.134). Unique Identifier : AIDSLINE ICA5/00186289
- Rote K; Holzman R; Robey G; Braun B; Knicker S; Severin J; Abbott Laboratories, North Chicago, IL, USA
- OBJECTIVE: Abbott Laboratories has produced a plasmid containing the gene for full length HIV-1 envelope protein p41 in Bacillus megaterium. The protein which contains the 45 C-terminal amino acids of gp120 was recovered as inclusion bodies following cell lysis. We have also expre
- Detection of antibodies to HIV-1 by a passive hemagglutination assay (retrocell HIV-1).
- Int Conf AIDS. 1989 Jun 4-9;5:374 (abstract no. W.B.P.135). Unique Identifier : AIDSLINE ICA5/00186389
- Kapsalis A; Wiesner D; Krene C; Traylor D; Scheffel J; Abbott Laboratories, North Chicago, IL, USA
- OBJECTIVE: To evaluate the sensitivity and specificity of a simple, passive hemagglutination assay for the detection of antibodies to HIV-1. METHODS: Stabilized human red cells (Duracytes) are coated with affinity purified p24 and gp41 HIV-1 viral antigens. The assay is initiated by mixing 50 ul of diluted patient ser
- Detection of IgM and IgA antibodies to HIV-1 after removal of IgG by protein G.
- Int Conf AIDS. 1989 Jun 4-9;5:374 (abstract no. W.B.P.136). Unique Identifier : AIDSLINE ICA5/00186489
- Weiblen B; Schmacher R; Hoff R; Massachusetts Department of Public Health, Center for Disease; Control, Boston, Massachusetts, USA
- OBJECTIVE: To develop sensitive and specific microassays for IgM and IgA antibodies to HIV-1 utilizing Protein G treatment to remove interfering IgG. METHODS: Twenty-five ul aliquots of plasma were treated with Protein G agarose (Genex) to remove IgG. Removal of IgG was confirmed by ELISA for IgG antibody to HIV-1. Tr
- Structural characterization of recombinant HIV-1 proteins p25 and p41 by HPLC protease V8 mapping and mass spectrometry.
- Int Conf AIDS. 1989 Jun 4-9;5:374 (abstract no. W.B.P.137). Unique Identifier : AIDSLINE ICA5/00186589
- Martin O; Buko A; Rote K; Dorwin S; Whatley H; Robey G; Abbott Laboratories, North Chicago, IL, USA
- OBJECTIVE: Abbott Laboratories has produced recombinant HIV p24 core protein and envelope protein p41. The recombinant p24 contains the full length sequence of HIB p24 with 12 residues from p17 and 44 residues from p15. The recombinant p41 contains the full length sequence of HIV
- A filter immunoplaque assay for the detection and enumeration of human HIV1 antibody secreting cells.
- Int Conf AIDS. 1989 Jun 4-9;5:374 (abstract no. W.B.P.138). Unique Identifier : AIDSLINE ICA5/00186689
- Vendrell J; Favero J; Huguet MF; Rabesandratana H; Serre A; Cannat A; INSERM U65, France
- OBJECTIVE: To allow the enumeration and the study of the circulating B cells shown to secrete specific HIV1 antibodies in vitro during the whole course of HIV1 infection. METHODS: PBMC from HIV1 infected and control subjects were incubated on nitrocellulose filters coated with either: HIV1 virus (Diagnostic Pasteur),
- Characterization and clinical significance of HIV p24 antibody.
- Int Conf AIDS. 1989 Jun 4-9;5:375 (abstract no. W.B.P.139). Unique Identifier : AIDSLINE ICA5/00186789
- McRae B; Thys R; Fico R; Falk L; Allain J; Abbott Laboratories, N. Chicago, Illinois, USA
- OBJECTIVE: Detect and quantitate p24 antibody (p24 Ab) to monitor natural history and therapy of HIV antigen (HIV Ag) negative individuals. METHODS: Solid phase was coated with recombinant p24 antigen to capture specific antibody. The same antigen labelled with HRPO was used as a probe. Titer and slope of p24 Ab were
- Evaluation of the wellcozyme recombinant enzyme immunoassay.
- Int Conf AIDS. 1989 Jun 4-9;5:375 (abstract no. W.B.P.140). Unique Identifier : AIDSLINE ICA5/00186889
- Cunningham PH; Imrie AA; Cooper DA; Centre for Immunology, St. Vincent's Hospital, Sydney, Australia
- OBJECTIVE: To evaluate the performance of the Wellcozyme HIV 1 Recombinant EIA in a clinical laboratory. METHOD: 1621 serum samples collected from patients with AIDS, ARC or Asymptomatic HIV infection and 36 serial serum samples from 3 seroconverting subjects were tested by the Wellcozyme assay; 5 other commercial EIA
- HIV-1 seropositive individuals recognize different epitopes of p17: potential for staging disease progression.
- Int Conf AIDS. 1989 Jun 4-9;5:375 (abstract no. W.B.P.141). Unique Identifier : AIDSLINE ICA5/00186989
- Naylor PH; Goldstein AL; Sinnadorai G; Sarin PS; Wang SS; The George Washington University Medical Center, Washington, DC
- OBJECTIVE: Development of an ELISA method to quantitate the levels of antibody to specific epitopes of HIV p17. METHODS: Synthetic peptides of 15 to 35 amino acids in length, representing the entire HIV p17 protein were synthesized. The presence of antibodies in serum to the peptides was determined using an ELISA proc
- Detection of HIV-1 antibodies in urines of asymptomatic and ARC /AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:375 (abstract no. W.B.P.142). Unique Identifier : AIDSLINE ICA5/00187089
- Gottfried T; Govindarajan AG; Kung J; Friedman-Kien A; Cao Y; Urnovitz HB; Calypte Biomedical Company, Berkeley, CA
- OBJECTIVE: We (AFK, YC) have reported detection of antibodies to HIV-1 in the urines of HIV-1 seropositive infected (H+) individuals using FDA licensed tests. In this study, using a recombinant protein dipstick format, we evaluate the detection of antibodies to HIV-1 in the urine of H
- Simple, easy to use HIV-1 recombinant antigen based blood antibody test.
- Int Conf AIDS. 1989 Jun 4-9;5:375 (abstract no. W.B.P.143). Unique Identifier : AIDSLINE ICA5/00187189
- Urnovitz HB; Mitra I; Govindarajan AG; Weiss T; Haight V; Gottfried T; Calypte Biomedical Company, Berkeley, CA, USA
- OBJECTIVE: Calypte Biomedical Company (CBC) has developed a simple and easy to use dipstick assay for HIV-1 antibodies. In this study, we evaluate the detection of antibodies to HIV-1 in the blood, serum or plasma of HIV-1 seropositive (H+) individuals. METHOD: A dipstick format with recombinant HIV-1 envelope and cor
- Proliferative response to soluble and microplate-absorbed gp41 synthetic peptide in HIV+ versus normal subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:375 (abstract no. W.B.P.144). Unique Identifier : AIDSLINE ICA5/00187289
- Gabiano C; Biglino A; Paiomba E; Pugliese A; Dalvanthal H; Istituto di Clinica Pediatrica e 'Istituto di Malattie Infettive,; Universita' di Torino, Torino, Italy
- OBJECTIVE: To detect specific cell-mediated immunity to a gp41 synthetic peptide, in soluble and absorbed form, in HIV+ individuals. METHODS: Peripheral blood mononuclear cells obtained from 10 HIV+ subjects (3 AIDS, 7 ARC; 5 adults, 3 children), were incubated in triplicate for 6 days with different concentrations of
- Direct detection of HIV-DNA in peripheral blood mononuclear cells from asymptomatic patients: comparison of three different probes.
- Int Conf AIDS. 1989 Jun 4-9;5:376 (abstract no. W.B.P.145). Unique Identifier : AIDSLINE ICA5/00187389
- Castillo I; Bartolome J; Martinez MG; Porres JC; Carreno V; Hepatology Unit, Fundacion Jimenez Diaz, Madrid, (Spain)
- Several methods allow the detection of HIV infection, being the nucleic acid hybridization the most useful and sensitivity one. The aim of this study was to directly determine the presence of HIV-DNA in peripheral blood mononuclear cells (PBMC) from anti-HIV positive patients, using 3 different HIV-probes. A total of
- Detection of anti-nef antibodies in sera of at risk individuals.
- Int Conf AIDS. 1989 Jun 4-9;5:376 (abstract no. W.B.P.146). Unique Identifier : AIDSLINE ICA5/00187489
- Verani P; Titti F; Butto S; Sernicola L; Rezza G; Lazzarin A; Rossi GB; Laboratory of Virology, Instituto Superiore di Sanita, Rome,; Italy
- OBJECTIVE: Nef gene seems to down regulate replication of HIV. It is suggested that following infection, antibodies anti-nef would be detected first and would remain the only detectable HIV-specific parameter during the variable period of latency. Moreover, in the hypothesis of the association of expression of nef pro
- Clinical and theoretical applications of new procedures for HIV rt and rt antibody (AB) quantitation.
- Int Conf AIDS. 1989 Jun 4-9;5:376 (abstract no. W.B.P.147). Unique Identifier : AIDSLINE ICA5/00187589
- Gronowitz JS; Neumuller M; Bhikhabhai R; Kallander CF; Fenyo ME; Albert J; Depts of Medical Virology, and (1) of Molecular Biology, Uppsala; University, Stockholm, Sweden
- In two accompanying abstracts ( ), we have shown the synthesis and usefulness of a new substrate 125I-Iododeoxyuridine triphosphate for RT analyses, as well as the construction of solid phase coupled templates to achieve further improvements potentiating the direct detection of RT activity in crude specimen. Due to th
- Passive agglutination with recombinant env antigen to detect antibodies to human immunodeficiency virus.
- Int Conf AIDS. 1989 Jun 4-9;5:376 (abstract no. W.B.P.148). Unique Identifier : AIDSLINE ICA5/00187689
- Proulx A; Riggin C; Cambridge BioScience Corporation, Worcester, MA, USA
- OBJECTIVE: To develop a simple and stable test for antibodies to human immunodeficiency virus (HIV-1) which requires no instrumentation and could be used for large scale screening. METHODS: Highly purified recombinant HIV env antigen, CBre3, was absorbed to blue polystyrene microbeads. A colloidal suspension (0.6% w/v
- Chemiluminescent detection of HIV infected cells using in-Situ hybridization assay technique.
- Int Conf AIDS. 1989 Jun 4-9;5:376 (abstract no. W.B.P.149). Unique Identifier : AIDSLINE ICA5/00187789
- Bronstein I; Kerschner JH; Voyta JC; Jablonski EG; Quest Systems, Inc., Bedford, MA
- Recently, we have developed a sensitive chemiluminescent assay for alkaline phosphatase and alkaline phosphatase conjugates based on adamantyl-stabilized dioxetane, AMPPD. (Voyta, J.C. et al, Clin. Chem. 34, 1157 (1988), Bronstein, I., et al, J. Biolum. Chemilum. 2, 186 (1988)). We have applied this chemiluminescent t
- Indirect immunofluorescence to detect anti-HIV antibody.
- Int Conf AIDS. 1989 Jun 4-9;5:376 (abstract no. W.B.P.150). Unique Identifier : AIDSLINE ICA5/00187889
- Croxson TS; Shah VJ; Strand CL; Polensky H; Holland PV; Randell R; Beth Israel Medical Center-NYC
- OBJECTIVE: An immunofluorescent method [IFA] (Fluorognost-HIV, Thermascan, Inc.) to detect anti-HIV antibody was compared to ELISA and Western blot [WB] (E.I. DuPont) methods. METHODS: Samples (n=10454) from 3 blood donation sites and samples from patients (n=1177) with known clinical histories (classified by CDC crit
- [HIV serology and infection with plasmodium falciparum]
- Int Conf AIDS. 1989 Jun 4-9;5:377 (abstract no. W.B.P.151). Unique Identifier : AIDSLINE ICA5/00187989
- Carme B; Copin N; Rosenheim M; Mpele P; Biendo M; Yala F; Centre Hospitalier et Universitaire de Brazzaville, Congo
- Elevated serum lactate dehydrogenase (LDH) in non-hospitalized AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:377 (abstract no. W.B.P.152). Unique Identifier : AIDSLINE ICA5/00188089
- Thomas S; Kaiser Foundation Hospital, Oakland, CA, USA
- OBJECTIVE: To evaluate use of LDH in early diagnosis of Pneumocystis carinii Pneumonia (PCP) in non-hospitalized AIDS patients (pts) METHODS: Retrospective review of 20 pts taking Zidovudine who had monthly LDH levels as part of routine followup. RESULTS: Isolated LDH elevations (normal hepatic transaminases and creat
- Evaluation of HIV1 antibody testing strategy in a mixed low risk/high risk population.
- Int Conf AIDS. 1989 Jun 4-9;5:377 (abstract no. W.B.P.153). Unique Identifier : AIDSLINE ICA5/00188189
- Downie J; Howard R; Bowcock B; Cunningham A; Virology Unit, ICPMR, Westmead Hospital, Westmead, 2145.; Australia
- Non-specific ELISA screening reactions in low risk persons invariably lead to atypical or indeterminate band profiles on Western blotting which must be evaluated alongside incomplete Western blot profiles of true HIV1 positive sera. METHOD: The Westmead HIV1 antibody testing strategy consists of the concurrent use of
- Significance of an indeterminate HIV Western blot (WBI).
- Int Conf AIDS. 1989 Jun 4-9;5:377 (abstract no. W.B.P.154). Unique Identifier : AIDSLINE ICA5/00188289
- Genesca J; Shih J; Jett B; Hewlett I; Epstein J; Alter H; Department of Transfusion Medicine and Division of Virology; (FDA), NIH, Bethesda, MD, USA
- OBJECTIVE: To determine the significance of a WBi result in a normal blood donor population at low-risk for HIV infection. METHODS: One hundred donors (D) to 50 recipients (R) were selected from prospective studies of post-transfusional hepatitis. Anti-HIV were tested by EIA (Dupont) and by a licensed WB assay (Biotec
- [Quantitative western blotting: value in the surveillance of HIV-seropositive patients]
- Int Conf AIDS. 1989 Jun 4-9;5:377 (abstract no. W.B.P.155). Unique Identifier : AIDSLINE ICA5/00188389
- Schiavini D; Puel J; Laboratoire de Virologie, CHU Purpan, Toulouse, France
- Field evaluation for the detection of HIV-1 specific igg antibodies (HIV-AB) in saliva: a cost-effective and accurate alternative to blood testing.
- Int Conf AIDS. 1989 Jun 4-9;5:377 (abstract no. W.B.P.156). Unique Identifier : AIDSLINE ICA5/00188489
- Behets F; Edidi B; Atikala L; Quinn TC; Brown C; Project SIDA, Kinshasa, Zaire
- OBJECTIVE: To determine the sensitivity and specificity for the detection of HIV-1 antibody in saliva using commercial ELISA and Western blot assays in a high risk population. METHODS: Saliva and serum samples were concurrently collected from 387 prostitutes and their 71 male clients in Kinshasa. Both serum and saliva
- Application of virus culture and pcr for HIV detection in blood donors with persistent anti-p24 reactivity in Western blot.
- Int Conf AIDS. 1989 Jun 4-9;5:378 (abstract no. W.B.P.157). Unique Identifier : AIDSLINE ICA5/00188589
- Van Der Poel C; Wester M; Reesink H; Tersmette M; Bruisten S; Huisman J; Red Cross Blood Bank, Amsterdam, The Netherlands
- OBJECTIVE: To investigate the presence of HIV in blood donors with persistent indeterminate anti-p24 reactivity in HIV Western Blot. METHODS: PBL from 11 blood donors with persistent anti-p24 in HIV WB, previously described as non infective to recipients of blood (Lancet 1986; ii: 752-753) and HIV positive cells were
- Anti-nef antibodies in blood donors with persistent anti-p24 reactivity in HIV Western blot, and characterisation with recombinant p24 in bidimential blot and ELISA.
- Int Conf AIDS. 1989 Jun 4-9;5:378 (abstract no. W.B.P.158). Unique Identifier : AIDSLINE ICA5/00188689
- Van Der Poel C; Gadelle S; Reesink H; Red Cross Blood Bank, Amsterdam, The Netherlands
- OBJECTIVE: To investigate the presence of anti-NEF antibodies as a marker of HIV infection in blooddonors with indeterminate anti-p24 HIV Western blot reactions, and to further characterize this reactivity employing recombinant p24 as antigen. METHODS: Serum samples of 11 blood donors with persistent isolated anti-p24
- Detection of HIV-1 specific antibodies and neutralizing activity (NT Act.) in the urine of seropositive persons.
- Int Conf AIDS. 1989 Jun 4-9;5:378 (abstract no. W.B.P.159). Unique Identifier : AIDSLINE ICA5/00188789
- Cao Y; Mirabile M; Li XL; Ho DD; Dietrich D; Friedman-Kien AE; New York University Med. Center, NY. NY
- OBJECTIVE: To detect antibodies to HIV-1, including neutralizing antibodies in urine samples from 56 HIV-1 seropositive individuals. METHODS: Fifty-six persons including 17 patients with AIDS-KS, 16 with AIDS-OI, 8 with ARC and 15 asymptomatic seropositive homosexual men were tested for HIV-1 specific antibodies in bo
- Comparison of Western blot (WB) interpretive criteria for HIV-1 antibody.
- Int Conf AIDS. 1989 Jun 4-9;5:378 (abstract no. W.B.P.160). Unique Identifier : AIDSLINE ICA5/00188889
- Schable C; George J; Phillips S; Schochetman G; Centers for Disease Control, Atlanta, GA, USA
- OBJECTIVE: To compare the four main proposed WB interpretations for their ability to confirm HIV-1 infection. METHODS: Proposed criteria include: I) Assoc State Terr Public Health Lab Directors (ASTPHLD), II) Consortium Retro Serol Stand (CRSS), III) American Red Cross (RC), IV) Dupont- FD
- The use of recombinant HIV ELISA kits as a secondary supplemental test for confirmation of HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:378 (abstract no. W.B.P.161). Unique Identifier : AIDSLINE ICA5/00188989
- Lepine D; Frenette S; O'Shaughnessy MV; Federal Centre for AIDS, Ottawa, Ontario, Canada
- Improvements in the sensitivity and specificity of HIV EIA kits and in the performance of supplemental confirmatory tests have made the serological diagnosis of HIV infection far more reliable in recent years. We initiated a study involving over 3000 sera to evaluate the performance of a Recombinant HIV ELISA Ab kit f
- Laboratory identification of recent HIV seroconversion: the utility of early repeat specimens and coordination with the counseling team.
- Int Conf AIDS. 1989 Jun 4-9;5:378 (abstract no. W.B.P.162). Unique Identifier : AIDSLINE ICA5/00189089
- Wilber JC; Louie B; Soncuya E; Back A; Brickman A; Lifson A; San Francisco Dept of Public Health San Francisco, CA, USA
- OBJECTIVE: To study the collection of followup specimens when there are apparent indeterminate results in a high risk population. The objective was to determine serologic patterns consistent with early seroconversion, minimize time of uncertainty for clients with indeterminate results, and communicate these findings t
- The d-mannose-specific lectin from gerardia savaglia blocks binding of HIV-1 to h9 cells in vitro.
- Int Conf AIDS. 1989 Jun 4-9;5:379 (abstract no. W.B.P.163). Unique Identifier : AIDSLINE ICA5/00189189
- Muller E; Reuter P; Renneisen K; Schroder HC; Institut fluur Physiologische Chemie, Universitat, Duesberweg 6,; 6500 Mainz, West Germany
- OBJECTIVE: To describe that lectins can be used as a tool to inhibit HIV infection in vitro. METHODS: Human T-Cells (H9), infected with HIV-1 have been used for the studies. RESULTS: The new (alpha-1-- greater than 2) D-mannose specific lectin from Gerardia savaglia is shown to prevent infection of H9 cells with HIV-1
- Early serologic evidence of infection with human immunodeficiency virus-type 1 (HIV-1).
- Int Conf AIDS. 1989 Jun 4-9;5:379 (abstract no. W.B.P.164). Unique Identifier : AIDSLINE ICA5/00189289
- Phair J; Crisler J; Huprikar J; Tsung L; Hart D; Chmiel J; Northwestern University Medical School and Howard Brown Memorial; Clinic, Chicago, Illinois, USA
- OBJECTIVE: To determine the prevalence and significance of indeterminant Western blot (WB) assays in homosexual men with negative Enzyme-Immunoabsorbent Assays (EIA). METHOD: The Chicago component of the MACS followed 396 EIA-negative men from 1984-85 through 10/1988. At 6 mo. intervals an EIA was obtained; WB were pe
- Is there a long 'silent' period before anti-HIV-1 serum antibodies appearance in HIV-1 infection?
- Int Conf AIDS. 1989 Jun 4-9;5:379 (abstract no. W.B.P.165). Unique Identifier : AIDSLINE ICA5/00189389
- Pineda JA; Leal M; Aguado I; Rey C; Torres Y; Lissen E; University of Seville. Seville. Spain
- Ranki have suggested that a period as long as 14 months can pass since HIV-1 infection is acquired to Anti-HIV-1 serum antibodies appearance, if a non-recombinant, type sandwich EIA (sEIA) is used to test them. However, if a recombinant, competitive EIA (cEIA) or a Western-Blot analysis (WB) are employed, antibodies
- Comparison of false positive reactions in direct binding anti-HIV elisa using cell lysate or recombinant antigens.
- Int Conf AIDS. 1989 Jun 4-9;5:379 (abstract no. W.B.P.166). Unique Identifier : AIDSLINE ICA5/00189489
- Craske J; Abbott R; Collier M; Martlew V; Love E; Lee D; National Blood Transfusion Service, Manchester and Lancaster,; Public Health Laboratory, Manchester, UK
- OBJECTIVE: Comparison of prevalence of false positive reactions in a commercial anti-HIV ELISA in blood donors using antigen from H9 infected cell lysates with those in the same assay using recombinant antigen. METHOD: In 1987-88 a commercial anti-HIV ELISA test using antigen from infected H9 cells was used to screen
- Negative results of in vitro tests for HIV1 antibody production by peripheral blood cells in 12 cases of isolated gag-encoded protein positivity.
- Int Conf AIDS. 1989 Jun 4-9;5:379 (abstract no. W.B.P.167). Unique Identifier : AIDSLINE ICA5/00189589
- Ducos J; Vendrell JP; Reynes J; Huguet MF; Cannat A; Serre A; INSERM U65, Laboratoire d'Immunologie, Hopital Lapeyronie,; France
- OBJECTIVE: To provide a help for the interpretation of ambiguous results observed in the course of systematic surveys: weak HIV1 seropositivity of ELISA tests, together with isolated bands of p25 (or other gag-encoded/protein) bands with no gp bands probably correspond to HIV1 false positivity and not to a very early
- Comparison of indirect immunofluroescence and Western blot tests for detection of antibody to human immunodeficiency - virus.
- Int Conf AIDS. 1989 Jun 4-9;5:379 (abstract no. W.B.P.168). Unique Identifier : AIDSLINE ICA5/00189689
- Gustavo B A; Peredo LV; Castillo TN; Herrera LR; Hospital de Infectologia, Centro Medico La Raza, I.M.S.S. Ciudad; de Mexico, Mexico.
- OBJECTIVE: To compare two confirmatory tests in the serological diagnosis of -- infection with A.I.D.S. virus. METHODS: 237 sera and 25 c.s.f. from the same number of people that were selected on the basis of screening enzyme immunoassay reactivity to A.I.D.S. -- virus were tested using Indirect Immunofluorescence (I.
- Resolution of indeterminate HIV Western blot results by additional testing.
- Int Conf AIDS. 1989 Jun 4-9;5:380 (abstract no. W.B.P.169). Unique Identifier : AIDSLINE ICA5/00189789
- Carlson JR; Yee JL; University of California, Davis, CA, USA
- OBJECTIVE: Current laboratory practice for the serological diagnosis of HIV infection involves initial screening of the specimen for anti-HIV antibody using an enzyme immunoassay (EIA) and validation of EIA positive results with Western blot (WB). The resolution of indeterminate WB results is a major problem in this a
- Prognostic value of repeated Western blot analysis.
- Int Conf AIDS. 1989 Jun 4-9;5:380 (abstract no. W.B.P.170). Unique Identifier : AIDSLINE ICA5/00189889
- Kamps B S; Niese D; Brackmann HH; Kamradt T; Euler P; van Loo B; Universitatsklinik Bonn, FRG
- OBJECTIVE: To assess the prognostic usefulness of Western blot testing in HIV-infection. METHODS: In 214 asymptomatic patients of the Bonn Hemophiliac Cohort Study Western blot analysis has been performed at intervals of 3 to 6 months since 1986. RESULTS: Only loss of anti-p24 or loss of anti-p17 was correlated with c
- Sensitivity of a new recombinant inhibition type ELISA system for the detection of HIV-1 antibodies.
- Int Conf AIDS. 1989 Jun 4-9;5:380 (abstract no. W.B.P.171). Unique Identifier : AIDSLINE ICA5/00189989
- Van Der Poel C; Lelie N; Reesink H; Plaisier A; Bakker E; Moshe-Sterk T; Red Cross Blood Bank, Amsterdam, The Netherlands
- OBJECTIVE: To establish the sensitivity of a new inhibition type ELISA for the detection of HIV-1 antibodies, employing recombinant antigens. METHODS: A serum panel of 1593 confirmed HIV-1 Western blot positive samples, classified as: clear (n=408), turbid (n-1139), hemolytic (n=46), obtained from asymptomatic individ
- Performance of a dot immunoblot kit for HIV antibody testing.
- Int Conf AIDS. 1989 Jun 4-9;5:380 (abstract no. W.B.P.172). Unique Identifier : AIDSLINE ICA5/00190089
- Sherlock C; Cook D; O'Shaughnessy M; Gill P; University of British Columbia and Provincial Laboratory,; Vancouver
- OBJECTIVE: To evaluate the performance of a dot immunoblot kit containing recombinant gp160 protein (MGSearch, MicroGeneSys) as a definitive screening and confirmatory HIV antibody test. METHODS: Sera were received for routine testing and were tested at the B.C. Provincial Lab by EIA (DuPont) and immunofluorescence (I
- Use of agglutination assays supplemental tests for antibody to HIV.
- Int Conf AIDS. 1989 Jun 4-9;5:380 (abstract no. W.B.P.173). Unique Identifier : AIDSLINE ICA5/00190189
- Tukei P; Nyamongo J; Mitchell S; Muniu E; Virus Research Centre, Kenya Medical Research Institute, Nairobi
- OBJECTIVE: To evaluate two agglutination assays for antibody to HIV as supplemental tests in field laboratories in Kenya . METHODS: A particle agglutination test (SERODIA-HIV, Fujirebio, Japan ) and a hemagglutination test (RETROCELL, Abbott, USA) w
- Performance appraisal of laboratories testing dried blood spot specimens for blinded HIV seroprevalence surveys in the United States.
- Int Conf AIDS. 1989 Jun 4-9;5:380 (abstract no. W.B.P.174). Unique Identifier : AIDSLINE ICA5/00190289
- Hannon H; Lewis S; McGee S; George R; Pappaioanou M; Center for Environmental Health and Injury Control
- OBJECTIVE: To determine and monitor the quality of analytical performance for HIV antibody analysis of dried blood spots (routinely collected for newborn screening programs) by laboratories participating in the blinded seroprevalence surveys of childbearing women. METHODS: Dried blood spot (DBS) specimens on filter pa
- Assessment of dried blood spot quality control and performance evaluation materials for national HIV seroprevalence surveys.
- Int Conf AIDS. 1989 Jun 4-9;5:381 (abstract no. W.B.P.175). Unique Identifier : AIDSLINE ICA5/00190389
- McGee S; Hannon H; Lewis S; Center for Environmental Health & Injury Control, Centers for; Disease Control, Atlanta, Georgia, USA
- OBJECTIVE: To characterize dried blood spot (DBS) materials prepared for quality assurance of laboratories screening for HIV seroprevalence. METHODS: DBS specimens were produced, characterized, and distributed for bench level controls and laboratory evaluation. Quality control (QC) materials were prepared on filter pa
- Chronic HIV Infection with delayed appearance of antibodies by usual techniques and a case of seroreversion.
- Int Conf AIDS. 1989 Jun 4-9;5:381 (abstract no. W.B.P.176). Unique Identifier : AIDSLINE ICA5/00190489
- McLaughlin B; Major C; Swantee C; Brunton J; Read S; Ontario Ministry of Health, Ontario, Canada
- We describe 2 unusual serology profiles from HIV-infected persons. Case 1: A 47 year old male, was intermittently symptomatic for a year, but not seropositive. The P24 Ag capture Assay was persistently reactive. HIV was isolated in 09/88. Case 2: A 33 year old female who presented an acute HIV encephalopathy and was s
- Reducing false reactive results when testing for antibodies to HIV-1.
- Int Conf AIDS. 1989 Jun 4-9;5:381 (abstract no. W.B.P.177). Unique Identifier : AIDSLINE ICA5/00190589
- Prensky W; Canguly ME; Lifshitz M; Brassel JH; Solanki D; Li Y; St. Clares Hospital and Health Center, New York, NY, 10019
- Sera from a population of 40,458 prospective immigrants to the US presently residing in New York City were tested for the presence of antibodies to HIV-1. Screening was with DuPont ELISA and confirmatory testing was with DuPont Western blot (WB) kits. By WB analysis there were 1,256 (3.1%) reactive and 514 (1.26%) inc
- Interpretation and follow-up of indeterminate Western blot (WB) test results.
- Int Conf AIDS. 1989 Jun 4-9;5:381 (abstract no. W.B.P.178). Unique Identifier : AIDSLINE ICA5/00190689
- Argirova R; Bodjeva E; Ivanova V; Beshkoy D; Troshev O; Central AIDS Lab., Institute for Infectious and Parasitic; Diseases, Bulgarian Medical Academy, Sofia, Bulgaria
- OBJECTIVE: To describe the follow-up of indeterminate in WB test persons. METHODS: 53 indeterminate persons (16 belonging to high risk and 37 - to low risk groups) were followed-up for 6-14 months (3-8 sera tested in 4-6 week intervals) using- WB HIV-1 IgG (DuPont, USA). RESULTS: The most characteristic patterns of in
- Evaluation of twelve commercial kits for screening of HIV-1 antibodies in Mexico.
- Int Conf AIDS. 1989 Jun 4-9;5:381 (abstract no. W.B.P.179). Unique Identifier : AIDSLINE ICA5/00190789
- Soler C; Mosqueira C; Morales C; Valdespino JL; Sepulveda J; Institute of Biomedical Research, National University of Mexico
- OBJECTIVE: To evaluate sensibility, specificity and operative performance of twelve commercial kits for use in screening programs for HIV-1 antibodies in Mexico . METHODS: A 775 sera panel, integrated by 32 AIDS patients sera, 49 HIV-1 seropositive sera, 42 sera from patients with p
- Neuropsychological function in physically asymptomatic HIV seropositive and seronegative gay/bisexual men.
- Int Conf AIDS. 1989 Jun 4-9;5:381 (abstract no. W.B.P.180). Unique Identifier : AIDSLINE ICA5/00190889
- Belsky-Barr D; Perry S; Swanda R; Barr W; Jacosberg L; Cornell Medical Center, USA
- OBJECTIVE: To determine if HIV-induced neuropsychological impairment occurs prior to physical manifestations of immunosuppression. METHODS: A 2-hour battery of standardized neuropsychological tests was administered to 20 HIV seropositive and 20 HIV seronegative gay/bisexual men matched for age, education and distress
- Immunological and psychological predictors of disease progression in gay males at risk for AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:382 (abstract no. W.B.P.181). Unique Identifier : AIDSLINE ICA5/00190989
- Fletcher MA; Ironson G; Laperriere A; Simoneau J; Klimas N; Schneiderman N; University of Miami, Miami, FL, USA
- OBJECTIVE: To determine the immunologic and psychologic factors which appear to be useful predictors of progression of HIV-1 infection. METHOD: A cohort of 24 gay males (participants in a larger study, in which they received their anti-HIV-1 status), were followed for 1 to 2 years. Six of these progressed in severity
- A comparison of neuropsychological testing and mental status exam in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:382 (abstract no. W.B.P.182). Unique Identifier : AIDSLINE ICA5/00191089
- Kobayashi J; Heaton R; Thompson L; Norton I; Cohn D; University of Colorado, Denver, Colorado, USA
- OBJECTIVE: To document the inaccuracy of a standardized mental status exam compared to neuropsychological (NP) testing in the assessment of cognitive function in people with AIDS. METHODS: NP testing (Numerical Attention; Symbol-Digit; Trails A, B; Story Recall and Figure Learning) and the NBCSE (Neurobehavioral Cogni
- Neuropsychiatric manifestations of HIV disease - St. Stephen's cohort study.
- Int Conf AIDS. 1989 Jun 4-9;5:382 (abstract no. W.B.P.183). Unique Identifier : AIDSLINE ICA5/00191189
- Riccio M; Jadresic D; Hawkins D; Wilson B; Thompson C; Charing Cross Hospital Southampton United Kingdom
- OBJECTIVE: To update our cohort study findings on association between HIV infection and neuropsychiatric morbidity. METHOD: Prior to notice of their HIV test results (in double blind conditions) gay men, first time attenders of an HIV clinic, are assessed with a standardized psychiatric interview (PSE) and neurologica
- Mood state, neuropsychology & self reported cognitive deficits in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:382 (abstract no. W.B.P.185). Unique Identifier : AIDSLINE ICA5/00191289
- Herns M; Newman S; McAllister R; Weller I; Harrison M; UCMSM, London UK
- OBJECTIVE: To examine the relationships between mood state, neuropsychological performance and self reported cognitive deficits in HIV+ve homosexual males. METHOD: 32 -ve and 77 well, +ve (CDC 2 + 3) were assessed using a comprehensive neuropsychological battery. Self reported and observer rated measures of mood were
- Neuropsychiatric disturbances in HIV-infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:382 (abstract no. W.B.P.186). Unique Identifier : AIDSLINE ICA5/00191389
- Cairoli S; Verri AP; Barbarini G; Parisi A; D'Avola G; Cerutti PG; 3rd Dept. of Neurology, IRCCS C. Mondino University of Pavia,; 27100 Pavia, Italy
- OBJECTIVE. To describe frequency, type, severity of affective/behavioral disturbances among HIV-infected patients in the different stages of the disease; to evaluate the personality traits of these patients. METHODS. The study included n. 113 subjects (M=77; F=36; mean age 26.9+/-5.4 yrs; i.v.drug abusers n.96/113) of
- Psychometric evaluations in Zidovudine treated patients - standardized test-procedures demonstrate measurable psychological improvement.
- Int Conf AIDS. 1989 Jun 4-9;5:383 (abstract no. W.B.P.187). Unique Identifier : AIDSLINE ICA5/00191489
- Jager H; Franke G; AIDS-Study Group, Schwabinger Krankenhaus, Munich, FRG
- OBJECTIVE: To evaluate the psychosocial impact of Zidovudine treatment in ARC and AIDS, 40 patients were sequentially tested using the SCL-90-R, a psychological symptom index. Medical, immunological and sociodemographic data were collected, in addition patients were staged using the Walter-Reed-Staging Classification.
- The use of medroxyprogesterone as pharmacologic treatment of hypersexuality in male patients with HIV-1 infection.
- Int Conf AIDS. 1989 Jun 4-9;5:383 (abstract no. W.B.P.189). Unique Identifier : AIDSLINE ICA5/00191589
- Schaerf FW; Koenig T; Wiser-Carlson B; Berlin F; The Johns Hopkins Hospital, Baltimore, MD, USA
- OBJECTIVE: To examine the efficacy of the anti-androgen medroxyprogesterone acetate (MPA, Depo-Provera) in reducing sexual urges and high-risk behavior in patients with hypersexuality and HIV-1 infection. METHODS: Four HIV-1 seropositive male patients aged 22-44 were seen in psychiatric consultation for suspected or s
- Norepinephrine response & immune functioning in HIV+ subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:383 (abstract no. W.B.P.190). Unique Identifier : AIDSLINE ICA5/00191689
- Kumar AM; Morgan R; Fletcher MA; Kumar M; Szapocznik J; Eisdorfer C; The Biopsychosocial Center on AIDS, University of Miami, School; of Medicine, Miami, Florida, USA
- Stress is one of the proposed cofactors that could influence the clinical course in HIV infection. This study of 43 HIV+ homosexual males examines the hypothesis that norepinephrine (NE) response to a cold pressor test is related to immune functioning in HIV+ subjects. A sample of blood for determining PHA stimulation
- Response to antidepressant therapy in depressed persons with advanced HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:383 (abstract no. W.B.P.191). Unique Identifier : AIDSLINE ICA5/00191789
- Fernandez F; Levy JK; Mansell PW; Baylor College of Medicine, USA
- OBJECTIVE: To determine differences in therapeutic response to two antidepressants in advanced HIV infection. METHOD: Twenty-eight subjects (19 ARC/9 AIDS) were selected as meeting DSM-III-R criteria for major depression. Subjects received either amitriptyline (AMI) or desipramine (DMI) in a randomly assigned fashion.
- Neuropsychological manifestations of HIV infection in gay men.
- Int Conf AIDS. 1989 Jun 4-9;5:383 (abstract no. W.B.P.192). Unique Identifier : AIDSLINE ICA5/00191889
- Stern Y; Sano M; Goldstein S; Mindry D; Richards M; Todak G; Williams JB; Ghrhardt A; Gorman J; New York State Psychiatric Institute, New York, NY, USA
- OBJECTIVE: Cognitive function in HIV+ individuals without AIDS may be impaired. However, prior studies have been limited by inappropriate control groups and failure to medically stage HIV. METHODS: Blind to HIV status, we administered tests assessing general intellectual function, memory, language, executive function,
- The use of the mini mental status exam as a cognitive screen in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:384 (abstract no. W.B.P.193). Unique Identifier : AIDSLINE ICA5/00191989
- Dilley JW; Boccellari A; Davis A; San Francisco General Hospital, UCSF School of Medicine San; Francisco, California, USA
- OBJECTIVE: To examine the utility of the Mini Mental Status Exam (MMSE) as a screening instrument in detecting cognitive deficits in patients with AIDS. METHODS: Hospitalized subjects (N=50) with first episode Pneumocystis carinii pneumonia (PCP) were given a battery of 10 neuropsychological tests (NP), Auditory Brain
- Tryptophan levels are unrelated to disturbances of mood in HIV-1 infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:384 (abstract no. W.B.P.194). Unique Identifier : AIDSLINE ICA5/00192089
- Keilp JG; Brew BJ; Heyes M; Sadler AE; Price RW; Sidtis JJ; Memorial Sloan-Kettering Cancer Center, NY, NY, USA
- OBJECTIVE: Disturbances of mood frequently accompany early symptoms of the AIDS Dementia Complex (ADC). Metabolism of tryptophan (TRYP), a serotonin precursor, is also disrupted by HIV-1 infection. In order to investigate a possible biochemical mechanism of mood disturbance in ADC, mood and psychiatric symptom ratings
- Neuropsychological and immunological abnormalities in advanced HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:384 (abstract no. W.B.P.195). Unique Identifier : AIDSLINE ICA5/00192189
- Fernandez F; Levy JK; Pirozzolo FP; Baylor College of Medicine, Houston, Texas, USA
- OBJECTIVE: To study the relationship between systemic immunodeficiency status and neurobehavioral impairment in advanced HIV infection. METHODS: Eighty subjects (39 ARC/41 AIDS) studied at entry for baseline neuropsychological testing were evaluated for their hematological and immunological status (white blood cell co
- A brief screening test battery for cognitive deficits in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:384 (abstract no. W.B.P.196). Unique Identifier : AIDSLINE ICA5/00192289
- Woo S; Hunter J; Wang P; Simor A; Wortzman G; Fernandes B; Bury A; Mount Sinai Hospital, University of Toronto, Toronto, Ontario,; Canada
- OBJECTIVE: (1) To design a brief screening measure with the capacity for early detection of neurocognitive impairment in HIV infected individuals. (2) To establish if scores on this measure may be used to infer the degree of CNS or immune impairment. METHODS: This is a 2 year longitudinal study of a case group with HI
- Drug use history in gay men with AIDS and its relation to neuropsychological findings.
- Int Conf AIDS. 1989 Jun 4-9;5:384 (abstract no. W.B.P.197). Unique Identifier : AIDSLINE ICA5/00192389
- SanGiovanni D; Boccellari A; Dilley JW; Davis A; San Francisco General Hospital, UCSF School of Medicine, San; Francisco, California, USA
- OBJECTIVES: To characterize the drug use histories of gay men with AIDS and to explore possible interactions of drug use with neuropsychological (NP) findings. METHODS: Self reported drug use histories for the prior 6 months and prior 7 years were obtained from 46 gay men during their first hospitalization for AIDS. T
- Relationship between neuropsychological and immune variables in HIV positive asymptomatic men.
- Int Conf AIDS. 1989 Jun 4-9;5:384 (abstract no. W.B.P.198). Unique Identifier : AIDSLINE ICA5/00192489
- Dilley JW; Boccellari A; Davis A; Moss A; Bacchetti P; Young M; San Francisco General Hospital, University of California San; Francisco School of Medicine San Francisco, California, USA
- OBJECTIVE: To describe the interrelationships between neuropsychological (NP) function, immune status and neuropsychiatric measures in asymptomatic HIV positive gay men. METHODS: Fifty-six asymptomatic gay men (HIV+=33, HIV-=23) were given a one time battery of NP tests and psychiatric rating scales. Measures of immun
- Cognitive dysfunction and psychosocial factors in symptomatic seropositive men.
- Int Conf AIDS. 1989 Jun 4-9;5:385 (abstract no. W.B.P.199). Unique Identifier : AIDSLINE ICA5/00192589
- Temoshok L; Canick JP; Sweet DM; University of California School of Medicine, San Francisco, CA.,; USA
- OBJECTIVE: Questions remain about the prevalence and severity of cognitive impairment along the spectrum of HIV disease. Our aim was to determine the presence and degree of cognitive impairment in symptomatic seropositive men, and whether severity was associated with certain psychosocial factors. METHODS: 103 seroposi
- Early diagnosis of HIV infection in infants.
- Int Conf AIDS. 1989 Jun 4-9;5:385 (abstract no. W.B.P.200). Unique Identifier : AIDSLINE ICA5/00192689
- d'Arminio MA; Novati R; Marchisio P; Zanchetta N; Lazzarin A; Tornaghi R; Massironi E; Infectious Dis. Clinic, Milan, Italy
- OBJECTIVE: To evaluate the role of serial IgM anti-HIV and p24Ag testing in the neonatal diagnosis of HIV infection. METHODS: 24 neonates from anti-HIV pos. mothers were followed-up bimonthly for 10+/-6 mo.s. At each time clinical, immunological (lymphocyte subsets, immunoglobulin levels) and serological (IgG anti-HIV
- Impact of HIV diagnosis on mood - St. Stephen's Cohort Study.
- Int Conf AIDS. 1989 Jun 4-9;5:385 (abstract no. W.B.P.207). Unique Identifier : AIDSLINE ICA5/00192789
- Jadresic D; Riccio M; Hawkins D; Wilson B; Thompson C; St. Stephen's Hospital, London; United Kingdom
- OBJECTIVE: To assess the impact of HIV positivity on mood state. METHOD: As part of the St. Stephen s prospective cohort study, mood is assessed prior to notification of HIV Ab status and reassessed 6 months later. Assessment consists in the following self-report questionnaires: HAD, POMS, STAI and a Physical Complain
- A VA hospital specialized psychiatry program for patients with HIV disease: a review of the first 50 referrals.
- Int Conf AIDS. 1989 Jun 4-9;5:385 (abstract no. W.B.P.202). Unique Identifier : AIDSLINE ICA5/00192889
- Vanderburg D; San Francisco Veterans Administration Hospital, San Francisco,; USA
- OBJECTIVE: To identify characteristics of a population of patients with HIV disease referred for outpatient psychiatric consultation in the San Francisco VA Hospital and to use these data for program planning purposes. METHODS: Since the first cases of HIV disease appeared at the San Francisco VA Hospital in 1982, the
- Request of mental health-care workers intervention by physicians attending HIV+ or AIDS patients: the importance of an integrated and multidisciplinary approach.
- Int Conf AIDS. 1989 Jun 4-9;5:385 (abstract no. W.B.P.203). Unique Identifier : AIDSLINE ICA5/00192989
- Cardoso G; Tostes M; Queiroz A; Navarro A; Zornitta M; Hospital Universitario CFF, Brazil
- OBJECTIVE: To identify and evaluate the reasons that make physicians, leading with HIV+ or AIDS patients, to request mental health-care workers approach. METHOD: Retrospective review of 124 patients assisted by mental health-care workers from a total of 439 registered patients attended in a National Reference Centre o
- Personality, behaviour and cognitive changes in AIDS as rated by patients and their careers and as related to neuropsychological test results.
- Int Conf AIDS. 1989 Jun 4-9;5:385 (abstract no. W.B.P.204). Unique Identifier : AIDSLINE ICA5/00193089
- Kocsis AE; Church J; Vearnals S; Green J; Paterson Wing, St. Mary's Hospital, London, W2 1NY, UK
- OBJECTIVES: To determine if; (1) Informal carers of AIDS patients notice changes in their partners which may be predictive of objective neuropsychological impairment; (2) Patients own perceptions are correlated with objective neuropsychological impairment. METHOD: The informal carers of AIDS patients (N=75) rated the
- Competency consolation to HIV patients: a liaison psychiatry perspective.
- Int Conf AIDS. 1989 Jun 4-9;5:386 (abstract no. W.B.P.205). Unique Identifier : AIDSLINE ICA5/00193189
- Weisman H; Perton L; Agnelli P; Queens Hospital Center Affiliation, Long Island Jewish Medical; Center, Jamaica, New York, USA
- OBJECTIVE: 1) To identify the reasons for competency consultation to patients infected with HIV, 2) to classify such consultations by psychiatric diagnosis and 3) to determine if the competency consultation provides a significant access route to mental health care for HIV patients. METHODS: All psychiatric competency
- [HIV positivity in psychiatry: observations over 18 months]
- Int Conf AIDS. 1989 Jun 4-9;5:386 (abstract no. W.B.P.206). Unique Identifier : AIDSLINE ICA5/00193289
- Zamperetti M; Goldwurm GF; Fernandez I; Sassoli V; Servizio Psichiatrico di Diagnosi e Cura Origgi I e Centro di; Medicina Comportamentale, Ospedale Ca Granda Niguarda, Milano,; Italy
- [Study of the demand for psychotherapy in 100 AIDS patients]
- Int Conf AIDS. 1989 Jun 4-9;5:386 (abstract no. W.B.P.207). Unique Identifier : AIDSLINE ICA5/00193389
- Edel Y; Ouvry O; Rognier-Aeberhard F; Marchand-Gonod N; Rodriguez J; Departement des Maladies Parasitaires et Infectieuses, et Sante; Publique, Unite INSERM 313 (Pr M. Gentilini), Groupe Hospitalier; Pitie-Salpetriere, Paris, France
- [Classification of psychiatric disorders according to DSM III-r during the course of AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:386 (abstract no. W.B.P.208). Unique Identifier : AIDSLINE ICA5/00193489
- Zamperetti M; Schlacht I; Ferrazzi D; Servizio Psichiatrico di Diagnosi e Cura Origgi I e Centro di; Medicina Comportamentale
- HIV seroprevalence study of involuntarily hospitalized mentally ill homeless from the streets of Manhattan, New York.
- Int Conf AIDS. 1989 Jun 4-9;5:386 (abstract no. W.B.P.209). Unique Identifier : AIDSLINE ICA5/00193589
- Empfield M; Weinstock A; Cournos F; Schrage H; Meyer I; Schoenbaum E; Creedmoor Psychiatric Center, Queens, NY
- OBJECTIVES: To determine the rate of HIV seroprevalence and risk taking behavior among a group of high risk psychiatric patients, i.e., the homeless mentally ill who shun health care services and are involuntarily hospitalized by mental health teams in New York City. METHODS: The study is conducted on The Creedmoor Ps
- Psychiatric diagnoses among volunteers for HIV testing.
- Int Conf AIDS. 1989 Jun 4-9;5:386 (abstract no. W.B.P.210). Unique Identifier : AIDSLINE ICA5/00193689
- Jacobsberg L; Perry S; Fishman B; Frances A; Ryan J; Fogel K; Cornell Medical Center, New York, NY
- OBJECTIVE: The determine the rates of DSM-III-R diagnoses among individuals volunteering for HIV serological testing. METHODS: We administered the Structured Clinical Interview for DSM-III-R (for Axis I) and the Personality Disorders Examination (for Axis II) one week prior to HIV serological testing to a heterogeneou
- Psychiatric diagnoses and treatment outcome in an AIDS specialty center.
- Int Conf AIDS. 1989 Jun 4-9;5:387 (abstract no. W.B.P.211). Unique Identifier : AIDSLINE ICA5/00193789
- Havens J; Finkelstein E; Viederman M; Jacobs J; New York Hospital-Cornell Medical Center, New York, New York, USA
- OBJECTIVE: We examined baseline patterns of psychiatric referrals, psychiatric diagnosis and treatment outcome in a cohort of PWA s in an AIDS specialty center. METHODS: Twenty-eight patients were referred for psychiatric evaluation and treatment in a six month period. This number represents 50% of inpatient admission
- Psychosocial status of 192 patients with HIV infection and AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:387 (abstract no. W.B.P.212). Unique Identifier : AIDSLINE ICA5/00193889
- King MB; Institute of Psychiatry, De Crespigny Park, London SE5, UK
- OBJECTIVE: Before planning psychological services for patients infected with HIV, we need epidemiological data on immediate and long-term psychological consequences of the diagnosis. METHODS: HIV positive outpatients were interviewed in a standardized manner at the HIV clinics of 2 London hospitals. RESULTS: 192 patie
- Analysis of initial psychiatric referrals from a hospital HIV service.
- Int Conf AIDS. 1989 Jun 4-9;5:387 (abstract no. W.B.P.213). Unique Identifier : AIDSLINE ICA5/00193989
- DiGiovanni C; Goyer PF; National Naval Medical Center, Bethesda, Maryland, USA
- OBJECTIVE: To determine patterns of initial utilization of psychiatric services by a hospital HIV program. METHODS: We reviewed 396 admissions to a military hospital s HIV service made by 354 patients over a 12-month period to determine the nature of initial requests for psychiatric consultation. RESULTS: Nearly 14% o
- A comparison of suicidal behaviors in patients in an AIDS related psychiatric clinic and in a general psychiatry clinic.
- Int Conf AIDS. 1989 Jun 4-9;5:387 (abstract no. W.B.P.214). Unique Identifier : AIDSLINE ICA5/00194089
- O'Dowd M; McKegney FP; Natali C; Harkavy J; Asnis G; Montefiore Med. Center, Albert Einstein College of Medicine,; Bronx, New York, USA
- OBJECTIVE: To assess the extent of suicidal behaviors in a population of AIDS, ARC and HIV positive patients. METHODS: 69 patients attending a psychiatric outpatient clinic for HIV related problems were surveyed as to past or present suicidal behaviors, and compared to a demographically matched sample of patients atte
- Psychiatric history among homosexuals and drug-addicts infected with human immunodeficiency virus.
- Int Conf AIDS. 1989 Jun 4-9;5:387 (abstract no. W.B.P.215). Unique Identifier : AIDSLINE ICA5/00194189
- Gala C; Martini S; Pergami A; Rossini M; Russo R; Lazzarin A; Institute of Psychiatry
- OBJECTIVE: to evaluate psychiatric history among HIV-infected subjects (homosexuals, drug-addicts and heterosexuals). METHODS: 218 subjects HIV-infected (II, III C.D.C.), 60 subjects at risk of HIV infection seronegative for antibody to HIV, 50 healthy heterosexual controls were recruited from the Dpt. of Infectious D
- A comparison of psychiatric consultations in AIDS and non AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:387 (abstract no. W.B.P.216). Unique Identifier : AIDSLINE ICA5/00194289
- O'Dowd MA; McKegney FP; Montefiore Medical Center, Albert Einstein College of Medicine,; Bronx, New York, USA
- OBJECTIVE: To identify differences between AIDS patients and age matched medical patients without AIDS seen in psychiatric consultation on the medical service of a large voluntary general hospital. METHOD: All psychiatric consultations done in one year on the acute medical service of a large voluntary hospital were re
- Establishment of an HIV related psychiatric clinic in an area of high substance abuse.
- Int Conf AIDS. 1989 Jun 4-9;5:388 (abstract no. W.B.P.217). Unique Identifier : AIDSLINE ICA5/00194389
- O'Dowd MA; Natali C; McKegney FP; Montefiore Medical Center, Albert Einstein College of Medicine,; Bronx, New York, USA
- OBJECTIVE: To describe an innovative psychiatric outpatient clinic for HIV related care and to identify factors related to patient drop out. METHOD: A psychiatric outpatient program was established in an area with a high rate of HIV infection among Hispanic and black intravenous drug users (IVDU) and their sexual part
- Effect of neuropsychiatric signs and symptoms on homeless persons with AIDS in a group residence.
- Int Conf AIDS. 1989 Jun 4-9;5:388 (abstract no. W.B.P.218). Unique Identifier : AIDSLINE ICA5/00194489
- Staats J; Hough G; Dornan D; AIDS Resource Center, New York, USA
- OBJECTIVE: To assess and manage HIV neuropsychiatric impairment in persons living in a residence for homeless persons with AIDS. METHODS: Consecutive admissions (N=120) to Baily House, a residence for 44 homeless persons with AIDS in New York City, were evaluated by a nurse-practitioner for psychiatric symptoms as a p
- Locus of control, social supports and depression among HIV infected subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:388 (abstract no. W.B.P.219). Unique Identifier : AIDSLINE ICA5/00194589
- Gala C; Martini S; Pergami A; Rossini M; Russo R; Durbano F; University of Milan, Medical School, Dept. of Psychiatry, Milan,; Italy
- OBJECTIVE: To evaluate the relationship among social supports, external-internal coping and psychopathological responses in subjects infected with Human Immunodeficiency Virus. METHODS: 125 subjects HIV infected (65 drug-addicts, 43 homosexuals, 17 heterosexuals) in CDC groups 2-3 were administered: 1) I-E Locus of Co
- Frequency of psychiatric disorders in hospitalized AIDS patients: comparison to a general hospital population.
- Int Conf AIDS. 1989 Jun 4-9;5:388 (abstract no. W.B.P.220). Unique Identifier : AIDSLINE ICA5/00194689
- Schaerf FW; Koenig T; Wisner-Carlson B; Johns Hopkins Hospital, Baltimore, Maryland, USA
- OBJECTIVE: To report results of psychiatric consultations on hospitalized AIDS patients and compare prevalences of diagnoses to those from general hospital consultations. METHODS: Eighty-five consecutive consultations (mean age 35) from the inpatient AIDS unit were compared to 85 consecutive general hospital (GH) cons
- Handedness and immune system function in gay/bisexual men: the multicenter AIDS cohort study (MACS).
- Int Conf AIDS. 1989 Jun 4-9;5:388 (abstract no. W.B.P.221). Unique Identifier : AIDSLINE ICA5/00194789
- Becker JT; Kingsley L; Bass S; Satz P; Dew MA; Penkower L; Selnes O; Sheridan K; Depts. Psychiatry, Neurology & Epidemiology, Univ. of Pittsburgh,; Pittsburgh, PA, USA
- OBJECTIVES: The purpose of the present study was to evaluate the relationships between handedness and immune system function in gay/bisexual men. Two hypotheses were tested: 1) gay/bisexual men are more likely to be left-handed; 2) left-handers are more likely to show impaired immune function. METHODS: Sixteen hundred
- Psychoneuroimmunologic studies of gay men with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:388 (abstract no. W.B.P.222). Unique Identifier : AIDSLINE ICA5/00194889
- Gorman JM; Williams J; Stern Y; Mayeux R; Goetz R; Kertzner R; HIV Center for Clinical and Behavioral Studies New York, NY, USA
- In order to explore possible relationships between psychiatric and neurological morbidity with medical and immunological status in patients with HIV infection, we began a five year follow-up study in October, 1987. At present, 196 gay men have been seen at least one time, 118 of whom were HIV seropositive at the time
- Psychiatric disorder and HIV infection: a controlled, longitudinal study.
- Int Conf AIDS. 1989 Jun 4-9;5:389 (abstract no. W.B.P.223). Unique Identifier : AIDSLINE ICA5/00194989
- Atkinson H; Grant I; Heaton R; Weinrich J; McCutchan J; Univ. of California, San Diego, CA, USA
- OBJECTIVE: To examine the prevalence of psychiatric disorder in various stages of HIV infection. We recently reported elevated lifetime prevalences of psychiatric disorder in HIV illness, and noted that onset of selected psychiatric disorders often preceded the AIDS pandemic, suggesting that some individuals might be
- Neuropsychological and psychosocial function in two cohorts of gay men: relation to stage of HIV-1 infection.
- Int Conf AIDS. 1989 Jun 4-9;5:389 (abstract no. W.B.P.224). Unique Identifier : AIDSLINE ICA5/00195089
- Saykin AJ; Janssen R; Sprehn G; Spira T; Cannon L; Kaplan J; O'Connor B; Watson S; Allen R; University of Pennsylvania, Philadelphia, USA
- OBJECTIVE: To characterize neuropsychological function, affective status and changes in activities of daily living in relation to stage of HIV infection. METHODS: Eighty-five HIV-1 seropositive gay men enrolled in prospective studies in Atlanta, GA, and San Francisco, CA, [Asymptomatic (ASX=35); Generalized Lymphadeno
- The effect of HIV antibody status on U.S. military applicant aptitude test scores.
- Int Conf AIDS. 1989 Jun 4-9;5:389 (abstract no. W.B.P.225). Unique Identifier : AIDSLINE ICA5/00195189
- Arday DR; Brundage JF; Gardner LI; Goldenbaum M; Wann F; Wright S; Walter Reed Army Institute of Research, Washington, DC, USA
- OBJECTIVE: To estimate the effect of HIV-1 seropositivity on Armed Services Vocational Aptitude Battery (ASVAB) test scores in otherwise healthy individuals with early HIV infection. METHODS: The ASVAB is a ten test written multiple aptitude battery, administered to all military enlisted applicants. Since 1 Oct 85, al
- A longitudinal analysis of perception of physical health and symptoms of depression in gay/bisexual men: the multicenter AIDS cohort study (MACS).
- Int Conf AIDS. 1989 Jun 4-9;5:389 (abstract no. W.B.P.226). Unique Identifier : AIDSLINE ICA5/00195289
- Becker JT; Zeger S; Dew MA; Karim R; Kingsley L; Satz P; Schaerf FW; Sheridan K; Depts. Psychiatry, Neurology & Epidemiology, Univ. of Pittsburgh,; Pittsburgh, PA, USA
- OBJECTIVES: The perception of symptoms of impaired physical health, specifically lymphadenopathy syndrome (LAS) has been associated with elevated scores on the Center for Epidemiological Studies- Depression scale (CES-D). The purpose of this study was to evaluate the change in this relationship during a four year foll
- Neuropsychiatric features of AIDS: a comparison with multiple sclerosis.
- Int Conf AIDS. 1989 Jun 4-9;5:389 (abstract no. W.B.P.227). Unique Identifier : AIDSLINE ICA5/00195389
- Morriss R; Schaerf FW; Brandt J; McArthur J; Folstein M; Department of Psychiatry, Leeds University, Leeds, UK
- OBJECTIVE: To compare rates of psychiatric disorders and cognitive functioning in outpatients with AIDS and ambulatory patients with Multiple Sclerosis (MS). METHODS: Twenty gay male AIDS outpatients, 20 gay male HIV-1 seronegative volunteers and 20 MS outpatients (steroid free) received a structured psychiatric inter
- Psychiatric findings in HIV-seropositive persons in a mandatory HIV screening program.
- Int Conf AIDS. 1989 Jun 4-9;5:389 (abstract no. W.B.P.228). Unique Identifier : AIDSLINE ICA5/00195489
- Rundell J; Brown G; Paolucci S; Uniformed Services University of the Health Sciences, Bethesda,; Maryland, USA
- OBJECTIVE: To determine the frequency of psychiatric diagnoses and degree of psychological distress in persons found to be HIV-infected in the U.S. military s mandatory HIV screening program. METHODS: 95 randomly selected HIV-infected military personnel were examined by board-certified psychiatrists. RESULTS: The most
- Auditory event related potentials (ERPs) in the clinical examination of HIV infected drug users.
- Int Conf AIDS. 1989 Jun 4-9;5:390 (abstract no. W.B.P.229). Unique Identifier : AIDSLINE ICA5/00195589
- Chiswick A; Egan V; Goodwin GM; St Clair D; Brettle RP; City Hospital; Royal Edinburgh Hospital; Edinburgh, EH10,; Scotland. United Kingdom
- OBJECTIVE: Slowing of the long latency ERP occurring some 300 msec. post stimulus has been detected in patients suffering from Alzheimer s disease. A prospective study of the ERPs of HIV infected Injection Drug Users (IDUs) was undertaken to detect the onset of HIV related dementia e
- Discriminating depression from cognitive impairment in HIV illness.
- Int Conf AIDS. 1989 Jun 4-9;5:390 (abstract no. W.B.P.230). Unique Identifier : AIDSLINE ICA5/00195689
- Grant I; Olshen R; Atkinson H; Heaton R; Weinrich J; McCutchan J; Univ of Calif, San Diego, CA, USA
- OBJECTIVE: To understand the relationship between depression and impaired neuropsychological (NP) performance in HIV illness. METHODS: Subjects were ambulatory homosexual men classed as CDC IV (N = 37) and CDC II-III (N = 58); and HIV negative homosexual (N = 34) and heterosexual (N = 27) controls, matched for age ande
- Preliminary findings on a screening symptom checklist for HIV dementia.
- Int Conf AIDS. 1989 Jun 4-9;5:390 (abstract no. W.B.P.231). Unique Identifier : AIDSLINE ICA5/00195789
- Boccellari A; Dilley JW; Davis A; Moss A; Bacchetti P; Wagner B; San Francisco General Hospital, University of California San; Francisco School of Medicine, Dept. of Psychiatry and UCSF AIDS; Health Project, San Francisco, California, USA
- OBJECTIVE: To describe the development of a screening self-report symptom checklist to detect individuals at risk for the development of HIV Related Dementia. METHODS: Seventy-nine subjects (56 HIV+ and 23 HIV-Controls) completed a 55 item checklist of HIV Related CNS symptoms. Subjects were also given a battery of nee
- Correlation of p300 auditory evoked potentials (AEPs) and tests of cognitive function in HIV positive drug users.
- Int Conf AIDS. 1989 Jun 4-9;5:390 (abstract no. W.B.P.232). Unique Identifier : AIDSLINE ICA5/00195889
- Egan V; Chiswick A; Goodwin G; St Clair D; Brettle RP; Depts. of Psychiatry/Infectious Diseases, Edinburgh, Scotland.; United Kingdom
- OBJECTIVE: In cortical/subcortical dementias AEPs, particularly P3 latency (the time the brain takes to make a tonal discrimination) slow. Neuropsychological (NP) testing enables specific cognitive deficits to be assessed. A prospective study of synchronously-infected drug users currently examines electrophysiologicale
- Relating depression to neuropsychological impairment.
- Int Conf AIDS. 1989 Jun 4-9;5:390 (abstract no. W.B.P.233). Unique Identifier : AIDSLINE ICA5/00195989
- Heaton R; Atkinson H; Grant I; Weinrich J; McCutchan A; University of California, San Diego, La Jolla, CA, USA
- OBJECTIVE: Since depression can affect neuropsychological (NP) functioning, we assessed whether observed NP deficits in men with HIV illness might be due to depressed mood. METHODS: Subjects were 72 homosexual men (CDC IV, N=9; CDC II/III, N=41; HIV-controls, N=22) participating in a longitudinal study of NP functionie
- The development of a brief screening battery to detect cognitive deficits in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:390 (abstract no. W.B.P.234). Unique Identifier : AIDSLINE ICA5/00196089
- Boccellari A; Davis A; Dilley JW; San Francisco General Hospital, University of California San; Francisco School of Medicine, Dept. of Psychiatry, and UCSF AIDS; Health Project, San Francisco, California, USA
- OBJECTIVE: To determine the clinical value of a brief screening battery in detecting cognitive deficits in patients with AIDS. METHODS: Fifty patients with AIDS were given the following battery of Neuropsychological tests (NP): Trail Making Test Part A & B (TMT), Wechsler Memory Scale Logical Memory & Visual Re
- Neuropsychological functioning in HIV-infection.
- Int Conf AIDS. 1989 Jun 4-9;5:391 (abstract no. W.B.P.235). Unique Identifier : AIDSLINE ICA5/00196189
- Schick U; Perro C; Naber D; Goebel FD; Psychiatrische Klinik der Universitat Munchen Medizinische; Poliklinik der Universitat Munchen
- OBJECTIVE: To study the natural history of neuropsychological deficits in patients with HIV-infection. METHODS: 132 HIV-positive patients, 100 in early stages, underwent psychiatric exploration and neuropsychological testing. Psychopathology was rated by means of the AMDP-System, self-rated by SDS, POMS, STAI and SCL.y
- Qualitative aspects of depressed mood and neuropsychological function in HIV-1+/- gay and bisexual men: the multicenter AIDS cohort study (MACS).
- Int Conf AIDS. 1989 Jun 4-9;5:391 (abstract no. W.B.P.236). Unique Identifier : AIDSLINE ICA5/00196289
- Becker JT; Schaerf FW; Kingsley L; Fox R; Dew MA; Depts. Psychiatry, Neurology & Epidemiology, Univ. Pittsburgh; Sch. Med, Pittsburgh, PA, USA
- OBJECTIVES: This study evaluated the relationship between measures of affect and cognitive function in HIV-1+/-) gay/bisexual men. METHODS: HIV-1 seropositive (n=157) and seronegative (n=113) gay/bisexual men from the Pittsburgh and Baltimore MACS sites completed the Beck Depression Inventory (BDI), Spielberger s Staty
- Evaluation of training for physicians at the national reference centers in Brazil.
- Int Conf AIDS. 1989 Jun 4-9;5:391 (abstract no. W.B.P.237). Unique Identifier : AIDSLINE ICA5/00196389
- Rodrigues J; Rodrigues L; Universidade de Brasilia - Brazil
- Under the sponsorship of the National Division of STD/AIDS, and evaluation of the clinical training on AIDS delivered by the three Reference Centers-Emilio Ribas (ER), Universidade Federal do Rio de Janeiro (UFRJ) and Gaffree & Guinle (G&G)- was carried out. The evaluation took into account guidelines set up by
- A comprehensive approach to community hospital care of AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:391 (abstract no. W.B.P.238). Unique Identifier : AIDSLINE ICA5/00196489
- Andrews L; Klimek J; Hartford Hospital, Hartford, Connecticut, USA
- OBJECTIVE: To provide clinical care, education, counseling, testing and social services to HIV infected patients (pts) served by an 850 bed tertiary care community teaching hospital in central Connecticut. METHODS: An AIDS Task Force acts in a reflective and advisory capacity, recommending policy and procedure to the
- Inverse correlation of complement-mediated antibody-dependent enhancing titers with stage of disease in individuals infected with HIV-1.
- Int Conf AIDS. 1989 Jun 4-9;5:391 (abstract no. W.B.P.239). Unique Identifier : AIDSLINE ICA5/00196589
- Mitchell WM; Montefiori DC; Robinson WE; Modliszewski A; Lefkowitz LB; Depts. Pathology and Preventive Medicine, Vanderbilt University,; Nashville, TN 37232 USA
- OBJECTIVE: Complement-mediated, antibody-dependent enhancement (C -ADE) of HIV-1 infection has been demonstrated to accelerate infection, to inhibit neutralizing antibody titers in vitro (Lancet i:790, 1988), and to cause a greater than 100 fold increase in infectious HIV-1 yields (JAIDS - in press). Our objective in
- Impediment to IVDA enrollment in ACTG Clinical Trials.
- Int Conf AIDS. 1989 Jun 4-9;5:391 (abstract no. W.B.P.240). Unique Identifier : AIDSLINE ICA5/00196689
- Fairchild P; Jaffarian C; Cheeseman S; Bova C; Tolson K; Blacklow N; University of Massachusetts Medical School, Worcester,; Massachusetts, USA
- OBJECTIVE: To ascertain reasons that hinder enrollment of HIV-infected intravenous drug abusers (IVDA) into clinical trials. METHODS: One hundred forty one IVDA (76 males + 65 females) were evaluated at UMMS for entry into NIH ACTG clinical trials assessing
- The role of the government of Canada in the nature and direction of clinical research in the management of HIV-Disease in Canada.
- Int Conf AIDS. 1989 Jun 4-9;5:392 (abstract no. W.B.P.241). Unique Identifier : AIDSLINE ICA5/00196789
- Khan SR; Joshi NN; Infection and Immunology Division, Bureau of Human Prescription; Drugs, Drugs Directorate, Health Protection Branch, Ottawa,; Canada
- OBJECTIVE: To identify and discuss the key role played by Health and Welfare Canada in supporting, expediting, facilitating, and implementing clinical research in the management of HIV-disease in Canada. METHODS AND RESULTS: The Health Protection Branch (HPB) of Health and Welfare e
- Thermographic imaging of HIV patients.
- Int Conf AIDS. 1989 Jun 4-9;5:392 (abstract no. W.B.P.242). Unique Identifier : AIDSLINE ICA5/00196889
- Clark R; Goff MR; Youle M; Gazzard B; Clinical Research Centre, Harrow, UK
- OBJECTIVE: To assess the role of high resolution infra-red imaging in HIV infection and Kaposi s sarcoma with particular reference to monitoring abnormal patterns that may arise because of peripheral neurological impairment and/or the presence of KS lesions. METHODS: High resolution thermal imaging equipment using an e
- Art therapy with people with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:399 (abstract no. W.B.P.243). Unique Identifier : AIDSLINE ICA5/00196989
- Sansom E; Couns MA; Counsellor, Art Therapist Casey House Hospice Inc. Toronto,; Ontario, Canada
- Abstract: Art Therapy is a useful medium for the expression, recognition and processing of the anxieties of People With AIDS. In this paper and slide presentation, issues of pain, incompletion, failure, isolation, dependency, punishment, fear of the unknown and homophobia are expressed in the artwork and subsequent die
- Maintenance of hope in the HIV sample.
- Int Conf AIDS. 1989 Jun 4-9;5:392 (abstract no. W.B.P.244). Unique Identifier : AIDSLINE ICA5/00197089
- Rabkin J; Williams J; Neugebauer R; Remien R; HIV Center for Clinical and Behavioral Studies, New York, NY, USA
- OBJECTIVE: To identify social and psychological conditions, susceptible to intervention, that contribute to maintenance of hope in an HIV sample. METHODS: 156 gay, predominantly white, well educated and financially successful community volunteers were evaluated to identify overall level of psychological functioning, pe
- A Rehabilitation program for clients with HIV associated conditions.
- Int Conf AIDS. 1989 Jun 4-9;5:392 (abstract no. W.B.P.245). Unique Identifier : AIDSLINE ICA5/00197189
- Gentile P; Marshall K; Bennett M; Laqueur P; Alexander H; Davis I; Woodhull Medical & Mental Health Center, Brooklyn, NY, USA
- OBJECTIVE: This poster presentation will highlight the special and unique role Rehabilitation Medicine can provide in servicing people with AIDs (PWas). METHODS AND RESULTS: Woodhull Medical & Mental Health Center, as part of NY Cities Health & Hospitals Corporation, provides comprehensive tertiary-care service
- Compliance of HIV-1nfected intravenous drug users in clinical trials.
- Int Conf AIDS. 1989 Jun 4-9;5:392 (abstract no. W.B.P.246). Unique Identifier : AIDSLINE ICA5/00197289
- Cheeseman S; Fairchild P; Glode M; Tolson K; Jaffarian C; Blacklow N; University of Massachusetts Medical School, Worcester,; Massachusetts, USA
- OBJECTIVE: To compare compliance of clinical trial subjects whose risk factor is intravenous drug abuse (IVDU s) with those from other risk groups. METHODS: Subjects are UMass patients in NIH ACTG placebo-controlled trials of Zidovudine in asymptomatic infection (019) and early ARC (016). IVDU s were either drug-free
- Insuring quality of data in community-based clinical trials.
- Int Conf AIDS. 1989 Jun 4-9;5:393 (abstract no. W.B.P.247). Unique Identifier : AIDSLINE ICA5/00197389
- Mitchell T; Child C; Weingart Z; Abrams D; San Francisco County Community Consortium, San Francisco, USA
- Community-based clinical trials of experimental HIV treatments offer the potential for rapidly expanding the number of drugs being tested, increasing participation by community physicians in HIV research, and improving access to promising experimental therapies for large numbers of patients. Critics of community-based
- [Evaluation of nursing workload: comparison between hospitalized patients infected and non-infected with AIDS]
- Int Conf AIDS. 1989 Jun 4-9;5:393 (abstract no. W.B.P.248). Unique Identifier : AIDSLINE ICA5/00197489
- Chidiac C; Chaussoy D; Beaucaire G; Leroy O; Senneville E; Mouton Y; Service des Maladies Infectieuses. Centre Hospitalier. F 59208; Tourcoing, France
- AIDS treatment registry (ATR) of New York.
- Int Conf AIDS. 1989 Jun 4-9;5:393 (abstract no. W.B.P.249). Unique Identifier : AIDSLINE ICA5/00197589
- Long I; Cowing M; Eigo J; Huff R; AIDS Treatment Registry, P.O.B. 30234, New York, New York, USA
- OBJECTIVE: To provide information about ongoing clinical trials to individuals seeking to enroll in clinical trials, physicians, health facilities and AIDS service organizations in New York and New Jersey. METHOD: A local, non-profit organization has established a computerized data base to give accurate, reliable info
- Atr: a regional model for establishing a community-based, computerized registry of AIDS/HIV clinical drug trials.
- Int Conf AIDS. 1989 Jun 4-9;5:393 (abstract no. W.B.P.250). Unique Identifier : AIDSLINE ICA5/00197689
- Eigo J; Cowing M; Long I; AIDS Treatment Registry, Inc. (ATR), P.O. Box 30234, New York,; New York 10011 USA
- OBJECTIVE: To establish community-based registries of AIDS/HIV-related clinical drug trials at local levels to increase awareness of, and access to, such trials for all persons affected by the epidemic, especially among minority populations heretofore largely excluded from enrollment. METHOD: Discussion of the steps t
- Program directors attitudes towards residents' care of persons with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:393 (abstract no. W.B.P.251). Unique Identifier : AIDSLINE ICA5/00197789
- Hayward RA; Kravitz RK; Shapiro MF; University of Michigan, Ann Arbor, Michigan, United States
- OBJECTIVE: To evaluate the educational strategies and experiences of United States residency programs regarding the training of primary care providers for persons with AIDS (PWAs). METHODS: We mailed questionnaires to directors of all 772 non-military United States internal medicine (I
- Impact of serum p24 HIV antigen screening on patient eligibility for antiviral clinical trials.
- Int Conf AIDS. 1989 Jun 4-9;5:393 (abstract no. W.B.P.252). Unique Identifier : AIDSLINE ICA5/00197889
- Heath-Chiozzi M; Pearlstein G; Eigenrauch H; Crumpacker C; Cotton D; Beth Israel Hospital, Harvard AIDS Clinical Trials Unit, Boston,; MA, USA
- OBJECTIVE: To examine the impact of serum p24 HIV antigen (p24) screening on patient eligibility for an antiviral clinical trial. METHODS: [ACTG #034 Phase I Trial of Ribavirin in the Treatment of Patients with AIDS and Advanced AIDS-Related Illnesses (ARC)] requires positive serum p24 for inclusion. Screening intervi
- New developments in a model program of AIDS hospice care.
- Int Conf AIDS. 1989 Jun 4-9;5:394 (abstract no. W.B.P.253). Unique Identifier : AIDSLINE ICA5/00197989
- Priebe B; Visiting Nurses and Hospice of San Francisco, CA, USA
- OBJECTIVE: To present the most current developments in a model program of comprehensive AIDS hospice care. METHODS: For five years Visiting Nurses and Hospice of San Francisco has provided both residential and inpatient AIDS hospice care. Utilizing interdisciplinary teams of nurses, social workers, volunteer service c
- A brief health status instrument for use in AIDS clinical trials.
- Int Conf AIDS. 1989 Jun 4-9;5:394 (abstract no. W.B.P.254). Unique Identifier : AIDSLINE ICA5/00198089
- Wu AW; Rubin HR; Mathews WC; Brysk LM; Hardy WD; Grant I; Richman DD; University of California, San Francisco, USA
- OBJECTIVE: While drug trials for HIV infection would ideally measure patients health status and quality of life, most available instruments are too long to be acceptable to investigators and subjects. We aimed to develop a brief yet valid questionnaire for use in clinical trials. METHODS: We modified the Medical Outc
- Neuropsychological test performance in HIV-1 seropositive patients on and off azidothymidine (AZT).
- Int Conf AIDS. 1989 Jun 4-9;5:394 (abstract no. W.B.P.255). Unique Identifier : AIDSLINE ICA5/00198189
- Sidtis JJ; Sadler AE; Keilp J; Brew BJ; Aronow HA; Price RW; Memorial Sloan-Kettering Cancer Center, NY, NY, USA
- OBJECTIVE: To compare the levels of neuropsychological and neurological performance in patients treated with ad hoc AZT with untreated patients. METHODS: The Neuro-AIDS Study Group (NASG) neurological history, examination, and neuropsychological batte
- Test-re-test performance on neuropsychological tests in a group of HIV-1 seropositive patients.
- Int Conf AIDS. 1989 Jun 4-9;5:394 (abstract no. W.B.P.256). Unique Identifier : AIDSLINE ICA5/00198289
- Sadler AE; Keilp JG; Thaler H; Brew BJ; Aronow HA; Price RW; Sidtis JJ; Memorial Sloan-Kettering Cancer Center, NY, NY, USA
- OBJECTIVE: To accurately evaluate test-re-test performance on the Neuro-AIDS Study Group (NASG) neuropsychological battery. In order to assess efficacy in treating the AIDS Dementia Complex (ADC) in prospective therapeutic studies, the effects of repeated testing must be understood. METHODS: A heterogeneous group of H
- New modalities for clinical trials: a synthesis of pharmacology and health care.
- Int Conf AIDS. 1989 Jun 4-9;5:394 (abstract no. W.B.P.257). Unique Identifier : AIDSLINE ICA5/00198389
- Harrington M; Eigo J; Kirschenbaum DZ; Long I; AIDS Coalition to Unleash Power, New York, NY, USA
- OBJECTIVE: To resolve the contradictions between the goals of those conducting clinical trials, who seek data, and those participating in them, who seek health care. METHOD: Protocol analysis, discussions with clinicians, researchers, officials and patient advocates. DISCUSSION: less than 5,000 people, (less than 0.5%
- Co-morbid events in first HIV identified hospitalizations, New York State (NYS), 1984-86.
- Int Conf AIDS. 1989 Jun 4-9;5:394 (abstract no. W.B.P.258). Unique Identifier : AIDSLINE ICA5/00198489
- DiFerdinando George J; Arthur K; Kaufman G; New York State (NYS) Department of Health, Albany, NY, USA
- OBJECTIVE: To describe the disease experience in those first hospitalized with HIV infection and/or sequelae in NYS acute care facilities between 1984 and 1986. METHODS: Discharge data abstracts (DDA) from all non-federal acute hospital stays in NYS were searched; any DDA with an ICD-9-CM diagnosis of 042-049, 795.8,
- Neuropsychological performance as a function of AIDS dementia complex (ADC) severity.
- Int Conf AIDS. 1989 Jun 4-9;5:395 (abstract no. W.B.P.259). Unique Identifier : AIDSLINE ICA5/00198589
- Sadler AE; Keilp JG; Dorfman D; Brew BJ; Aronow HA; Price RW; Sidtis JJ; Memorial Sloan-Kettering Cancer Center, NY, NY, USA
- OBJECTIVE: To review the sensitivity of the Neuro-AIDS Study Group (NASG) neuropsychological battery as a function of clinical severity of cognitive, motor, and behavioral dysfunction in ADC. METHODS: 210 HIV-1 seropositive patients at various stages of disease who were not receiving anti-viral therapy and whose evalu
- The organization of AIDS services at cook county hospital, Chicago.
- Int Conf AIDS. 1989 Jun 4-9;5:395 (abstract no. W.B.P.260). Unique Identifier : AIDSLINE ICA5/00198689
- Sherer R; Kathpalia S; Sable R; Cohen M; Gath L; Hamb A; AIDS Prevention Service (CCHAPS) and Section of Retrovirology,; Division of Infectious Disease; Cook County Hospital, Chicago,; IL, USA
- OBJECTIVE: To implement a rational and comprehensive AIDS service organization for a diverse, multi-racial indigent population based in the only public hospital in Chicago. METHODS: Distinct expertise and service capability for persons with AIDS, HIV infection, and risk for HIV evolved in the Divisions of General Medi
- Clinic for HIV-related concerns: one model of outpatient psychiatric care.
- Int Conf AIDS. 1989 Jun 4-9;5:395 (abstract no. W.B.P.261). Unique Identifier : AIDSLINE ICA5/00198789
- Woo S; University of Toronto, Toronto, Ontario, Canada
- OBJECTIVE: To provide an example of a model of care for outpatient psychiatric and psychosocial services in Canada . Such a model can then be used as a basis for developing suitable clinics in other areas of the country where these services are required. The Clinic for HIV-Related C
- Principles of rehabilitation of patients with immunodeficiencies.
- Int Conf AIDS. 1989 Jun 4-9;5:395 (abstract no. W.B.P.265). Unique Identifier : AIDSLINE ICA5/00198889
- Sepiashvili R; Immunological center, Tskhaltubo, George SSR, USSR
- Rehabilitation of immune system is a complex and versatile process which includes not only medical but professional, social and psychological aspects as well. It has its own peculiarities and regularities at different pathological processes constituting the base of a new field of knowledge in medical science, immunolo
- Sacramento cares: one communities response to providing comprehensive medical care to people with HIV-related disorders.
- Int Conf AIDS. 1989 Jun 4-9;5:395 (abstract no. W.B.P.263). Unique Identifier : AIDSLINE ICA5/00198989
- Flynn N; Riley J; Pomerantz S; Grant S; Wolf M; McCandless L; University of California, Davis (UCD)
- OBJECTIVE: To develop a system of medical care to meet the need for comprehensive, coordinated, high-quality care for people with HIV infection in the Sacramento, CA area, which has a total of greater than 600 reported cases of AIDS. METHODS: To reach our objective, local hospitals, AIDS agencies, physicians (P), and
- Referral patterns in a comprehensive AIDS clinic.
- Int Conf AIDS. 1989 Jun 4-9;5:395 (abstract no. W.B.P.264). Unique Identifier : AIDSLINE ICA5/00199089
- Lee S; The New York Hospital-Cornell Medical Center, NY, NY, USA
- OBJECTIVE: To assess referral patterns of physicians in a comprehensive AIDS clinic with regards to source and number of referrals. METHODS: Comprehensive services at the New York Hospital-Cornell Medical Center are provided by 4 primary physicians (2 infectious disease specialists, a hematologist and an internist) 2
- Clinical care as part of integrated AIDS management in a Zambian rural community.
- Int Conf AIDS. 1989 Jun 4-9;5:396 (abstract no. W.B.P.265). Unique Identifier : AIDSLINE ICA5/00199189
- Chela CM; Campbell ID; Siankanga Z; The Salvation Army Chikankata Hospital, Mazabuka, Zambia
- OBJECT: 1) to present an analysis of clinical symptomatology with a summary of major protocols for clinical management of hospital inpatients compared with patients in the home based care and prevention programme; 2) to analyse drug use and drug costs in the hospital and in the home based care setting. METHODS: A retr
- Study of a series of 121 consecutive AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:396 (abstract no. W.B.P.266). Unique Identifier : AIDSLINE ICA5/00199289
- Correa-Lima MB; Silva MA; Brandao-Mello CE; Leite CT; Haddad LR; Fonseca MA; Clinica Medica A, of the Universidade do Rio de Janeiro,; UNI-RIO, Brazil
- The aim of the work was to study epidemiologically, Clinically and laboratorially a series of 121 consecutive AIDS patients, admitted to the Clinica Medica A of the Universidade do Rio de Janeiro, during the 1985-88 period. METHODS: All the 121 consecutively admitted patients were studied trying to figure out the poss
- AIDS issues for rural hospitals in U.S. frontier areas.
- Int Conf AIDS. 1989 Jun 4-9;5:396 (abstract no. W.B.P.267). Unique Identifier : AIDSLINE ICA5/00199389
- Carwein V; Berry D; University of Nevada, Las Vegas, Nevada, USA
- OBJECTIVE: To identify and assess the experiences rural frontier hospitals (under 50 beds) in 8 western states have had in the provision of care to HIV infected patients and to evaluate the preparedness of these hospitals to provide AIDS care via education and policy development. METHODS: A survey addressing the incid
- Seroprevalence of HIV, herpes viruses and immunologic abnormalities in a group of IV drug abusers.
- Int Conf AIDS. 1989 Jun 4-9;5:396 (abstract no. W.B.P.268). Unique Identifier : AIDSLINE ICA5/00199489
- Pachucki CT; Schaaff D; Lentino J; Schaefer M; Dorus W; Edward Hines V.A. Hospital, Hines, IL, USA
- OBJECTIVE: To determine the prevalence of infection with Epstein Barr Virus (EBV), Cytomegalovirus ( CMV ), herpes simplex virus, (HSV), and HIV, and to correlate seroprevalence with immunologic abnormalities in a group of IV drug abusers. METHODS: HIV status was
- Psychosocial issues associated with human immunodeficiency virus (HIV) infection in a city hospital: experience of the multidisciplinary patient care meeting.
- Int Conf AIDS. 1989 Jun 4-9;5:396 (abstract no. W.B.P.269). Unique Identifier : AIDSLINE ICA5/00199589
- Cheung T; Weissman H; Montreuil A; Queens Hospital Center (QHC), Affiliation of the Long Island; Jewish Medical Center, Jamaica, NY, 11432, USA
- OBJECTIVE: To survey the prevalence and range of psychosocial issues associated with HIV infection as discussed at QHC AIDS Team multidisciplinary meetings. METHODS: Records of the AIDS multidisciplinary patient care meetings at QHC from March, 1988 to October, 1988 were evaluated for psychosocial issues presented. Th
- Triage system for potential research subjects into active AIDS clinical trials.
- Int Conf AIDS. 1989 Jun 4-9;5:396 (abstract no. W.B.P.270). Unique Identifier : AIDSLINE ICA5/00199689
- DeGenova V; Mills J; Holland R; Feigal D; Volberding P; Nash M; University of California, San Francisco, San Francisco General; Hospital USA
- OBJECTIVE: To facilitate accrual of potential research subjects by prescreening volunteers, collecting important laboratory and clinical data, identifying individuals and specific populations for a targeted recruitment effort. METHODS: A data base has been created to facilitate accrual into active AIDS clinical trials
- Assessment of the needs of a HIV acute/chronic level care unit.
- Int Conf AIDS. 1989 Jun 4-9;5:397 (abstract no. W.B.P.271). Unique Identifier : AIDSLINE ICA5/00199789
- Scheib R; Marks S; Bradley O; Desroches A; Morgan B; Baer J; Lemuel Shattuck Hospital, Tufts U. Schl. of Med., Boston, MA, USA
- To date the traditional medical model of acute and chronic level care has been used to provide services to the affected HIV population. There has been increasing demand for chronic level care beds to alleviate hospital acute care bed use. This study presents data from the Lemuel Shattuck Hospital HIV Unit which provid
- The role of the pharmacist in the HIV team.
- Int Conf AIDS. 1989 Jun 4-9;5:397 (abstract no. W.B.P.272). Unique Identifier : AIDSLINE ICA5/00199889
- Fitt SM; Runn RJ; McManus T; Moxham J; Pharmacy Department, Dulwich Hospital
- OBJECTIVE: To discuss the role of the pharmacist in the management of HIV and AIDS patients. METHOD: In April, 1988 a pharmacist was appointed to the team managing HIV and AIDS patients in Camberwell Health Authority. RESULTS: The appointment has led to a large pharmaceutical input into the management of this group of
- Causes of hospitalizations following AIDS diagnosis in a population-based cohort.
- Int Conf AIDS. 1989 Jun 4-9;5:397 (abstract no. W.B.P.273). Unique Identifier : AIDSLINE ICA5/00199989
- Hulman SJ; Modesitt S; Klockner R; Bennett D; Fleming D; Oregon Health Division, Portland, Oregon, USA
- OBJECTIVE: To accurately determine causes of hospitalizations after an AIDS diagnosis by following all cases in a statewide population-based cohort. METHODS: We follow all AIDS cases detected by active AIDS surveillance in Oregon who remain in the state for follow-up medical care. At six month intervals, we review eac
- Tuberculin skin testing in HIV infected persons.
- Int Conf AIDS. 1989 Jun 4-9;5:397 (abstract no. W.B.P.274). Unique Identifier : AIDSLINE ICA5/00200089
- Banerjee C; Cromwell G; Furth P; University of Maryland Medical School, Baltimore, Maryland, USA
- HIV infection is a probable risk factor for reactivation of latent M.Tb. but there is little data on the value of tuberculin skin testing in HIV infected persons. We prospectively evaluated the diagnostic utility of 1 and 2 step PPDs, anergy panels (mumps and candida) and chest x-rays to identify latent M.Tb. infectio
- Cellular pharmacology and clinical pharmacokinetics of 2', 3'- dideoxyadenosine and 2', 3' -dideoxyinosine.
- Int Conf AIDS. 1989 Jun 4-9;5:397 (abstract no. W.B.P.275). Unique Identifier : AIDSLINE ICA5/00200189
- Hartman NR; Yarchoan R; Ahluwalia GS; Kelley JA; Broder S; Johns DG; National Cancer Institute, Bethesda, MD, USA
- OBJECTIVE: To study the cellular pharmacology and the clinical pharmacokinetics of 2 , 3 -dideoxyadenosine (ddA) and 2 , 3 dideoxyinosine (ddI), anti-HIV agents with low in vitro cytotoxicity. METHODS: Samples from AIDS or ARC patients receiving oral or IV ddA or ddI are analyzed by reversed-phase HPLC. Phosphorylat
- [Immunostimulation as support therapy in AIDS patients and HIV seropositives]
- Int Conf AIDS. 1989 Jun 4-9;5:397 (abstract no. W.B.P.276). Unique Identifier : AIDSLINE ICA5/00200289
- Kornaszewski W; Lurhuma Z; Lutete K; Mbula M; Skotnicki A; Universite de Kinshasa, Zaire, Departement d'Hematologie; Cracovie, Pologne
- Diethyldithiocarbamate inhibits the progression of HIV infection: results of a prospective randomized clinical study.
- Int Conf AIDS. 1989 Jun 4-9;5:398 (abstract no. W.B.P.277). Unique Identifier : AIDSLINE ICA5/00200389
- Dietrich M; Bernhard-Nocht-Institute for Tropical Medicine, Clinical; Department, Germany
- OBJECTIVE: Diethyldithiocarbamate (DTC) is a chelating agent with in vitro and in vivo influence on the production of HIV. Recently, J.M. Lang et al. (Lancet, Sept. 24th, 1988, 702-705) presented their data of a 4-month treatment study with positive response both in improvement of patients and increase in T4-CELLS. In
- Treatment of HIV-1nfected patients with D-penicillamine tentative clinical and immunological results.
- Int Conf AIDS. 1989 Jun 4-9;5:389 (abstract no. W.P.B.278). Unique Identifier : AIDSLINE ICA5/00200489
- Hoffken G; Bieniek B; Ludwig W; Lode H; Mielke M; Zorr B; Med. Clinic of Klinikum Steglitz Berlin, FRG
- OBJECTIVE: To evaluate the compatibility and clinical, immunological and virological efficacy of D-penicillamine before, during and after a 6-week therapy in HIV-1 seropositive patients (pts). METHODS: On-going prospective randomizedplacebo- controlled study, test criteria: lymphocyte-subsets (CD3+, CD4+, CD8+)CD8+ /L
- Recovery of delayed-type hypersensitivity (DTH) in patients with AIDS-related complex (ARC) in randomized trial of imreg-1.
- Int Conf AIDS. 1989 Jun 4-9;5:398 (abstract no. W.B.P.279). Unique Identifier : AIDSLINE ICA5/00200589
- Fiala M; Cone LA; Sayre J; Eisenhower Medical Center, Rancho Mirage, CA, USA
- OBJECTIVES: IMREG-1, an immunoregulator containing tyrosine- glycine (-glycine) enhances multiple immune functions. We have studied IMREG-1 in patients with ARC or Kaposi s sarcoma (KS) regarding efficacy and immunoenhancing effects. METHODS: Forty anergic patients in Southern California were tested every 2-3 months w
- Effect of isoprinosine on HIV-antigenemia.
- Int Conf AIDS. 1989 Jun 4-9;5:398 (abstract no. W.B.P.280). Unique Identifier : AIDSLINE ICA5/00200689
- Teglbiaerg L; Kroon S; Moestrup T; Hansson BG; Hvidovre Hospital, Denmark
- OBJECTIVE: To evaluate the effect of isoprinosine on HIV-antigen levels. METHODS: A multicentre, double-blind placebo controlled study of Isoprinosine was carried out in 21 clinical centers in Denmark and
- Induction of t lymphocyte-related functions by imuthiol through down regulation of prostaglandins secretion by monocytes/ macrophages.
- Int Conf AIDS. 1989 Jun 4-9;5:398 (abstract no. W.B.P.281). Unique Identifier : AIDSLINE ICA5/00200789
- Mossalayi MD; Dalloul AH; Bertho JM; Debre P; CHU Pitie-Salpetriere, Paris, France
- OBJECTIVE: Description of immunostimulating effect of Imuthiol (sodium ditiocarb, DTC). METHODS: PBL, their adherent subsets and T-Cells were assayed for their capacity to produce IL2 and their mitogenic response to PHA with/without 10(-7) mg/ml Imuthiol. The effect of Imuthiol on IL1 and PGE 2 secretion by adherent c
- A multicenter randomized double-blind placebo controlled dose-response trial of lf 1695 in p24-antigen seropositive patients.
- Int Conf AIDS. 1989 Jun 4-9;5:398 (abstract no. W.B.P.282). Unique Identifier : AIDSLINE ICA5/00200889
- Roue R; Kienzler JL; Dormont D; Fleury H; Lang JM; Mouton Y; Hopital Militaire Begin, Saint-Mande, France
- OBJECTIVE: LF 1695 is a synthetic biological response modifier with immunorestoring and enhancing effects in animal as well as in human in-vitro and in-vivo. He has also shown in some in-vitro experiments an inhibitory effects on HIV-1 replication. On the basis of these findings, we conducted a clinical trial to evalu
- As 101, a new immunodulating compound in the treatment of AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:399 (abstract no. W.B.P.283). Unique Identifier : AIDSLINE ICA5/00200989
- Laporte JP; Lebas J; Gonzales G; Meyohas M; Srendi B; Najman A; St Antoine Cooperative Group on AIDS 75012 Paris France
- AS 101 (Nature 1987, 330:173-176) was administered IV 3 times a week at the dosage of 5 mg/m2 on AIDS patients. 44 patients entered the study (41 M, 3 F) median of age 27 (22-61) years. CDC staging: stage IV all of them (C:30 patients, D:14, A:3, B:5). HIV antigenemia was positive in 50% of the cases. Most patients we
- Enhancement of T-Cell growth, in HIV+ patients treated with ditiocarb (IMUTHIOL): evidence for monocyte involvement.
- Int Conf AIDS. 1989 Jun 4-9;5:399 (abstract no. W.B.P.284). Unique Identifier : AIDSLINE ICA5/00201089
- Dalloul AH; Kirstetter M; Debre P; CHU Pitie-Salpetriere, 91 Bd de l'Hopital, 75013 Paris,; France
- OBJECTIVE: Testing the in-vivo immunostimulating effect of Imuthiol (sodium ditiocarb, DTC). METHODS: 48 HIV+ patients were randomized into two groups: 22 had no treatment, and 26 were given Imuthiol (10 mg/kg weekly for 8 weeks). Blood was collected, and mononuclear cells assayed for the following: T colony formation
- Survival rate in AIDS patients following transfusion. Therapy with CR1 enriched erythrocytes.
- Int Conf AIDS. 1989 Jun 4-9;5:399 (abstract no. W.B.P.285). Unique Identifier : AIDSLINE ICA5/00201189
- Sulzberger J; Inada Y; McKinley GF; Ikegami H; Senderowicz A; Lange M; St. Luke's -Roosevelt Hospital Center, Columbia University, New; York, NY, USA
- OBJECTIVE: Erythrocyte C3b receptors (CR1) play a crucial role in the inactivation and clearance of circulating immune complexes. We previously reported the induction of temporary clinical remission in AIDS patients (Pt) following transfusion (Tx) of CR1 enriched packed erythrocytes (PRC). We report our data using thi
- Peptide T phase I study: immuno/virologic results.
- Int Conf AIDS. 1989 Jun 4-9;5:399 (abstract no. W.B.P.286). Unique Identifier : AIDSLINE ICA5/00201289
- Goodwin FK; Heseltine P; Bridge TP; Martin J; Leedom JM; National Institute of Mental Health, Bethesda, MD
- OBJECTIVE: To evaluate the toxicity and possible response measures to Peptide T (D-ala-1-peptide-T-amide), a homologous of VIP and gp-120, and gp-120 receptor blocker. METHODS: In this ongoing study, 9 AIDS and 5 ARC patients have received IV Peptide T (dose range:.06-.8mg/kg/day) or intranasal (25 mg/day). For 12 wee
- Dose response study of daily diethyldithiocarbamate (DTC) in patients with ARC/AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:399 (abstract no. W.B.P.287). Unique Identifier : AIDSLINE ICA5/00201389
- Petersen EA; Hersh E; Fish D; Kaplan C; Gorman R; Darrogh M; Department of Internal Medicine, University of Arizona, Tucson,; AZ, USA
- OBJECTIVE: Daily DTC at a dose of 200-600 mg/kg (equivalent to 600-1800 mg/m(2) human) is clearly effective in treating mice infected with LP-BM5. Weekly dosage is less so. Thus, this study was designed to determine the toxicity effect of DTC given daily to patients with ARC or AIDS. METHODS: Patients with AIDS or ARC
- The effect of isoprinosine R (inosine pranobex) (IP) in HIV-seropositive patients with low risk for developing AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:399 (abstract no. W.B.P.288). Unique Identifier : AIDSLINE ICA5/00201489
- Loveless MO; Robins DS; US/UK Isoprinosine Clinical Investigators Group, USA
- Laboratory studies have suggested modest improvements in mitogen response and IL-2 production in peripheral blood lymphocytes from HIV-infected patients treated with IP. Small scale studies of HIV-patients treated with IP have demonstrated increases in T-helper cell co
- Effect of oral dextran sulfate on the mouse intestine.
- Int Conf AIDS. 1989 Jun 4-9;5:400 (abstract no. W.B.P.289). Unique Identifier : AIDSLINE ICA5/00201589
- Wells CL; Erlandsen SL; Rhame FS; University of Minnesota, Minneapolis, Minnesota, USA
- OBJECTIVE: Because oral dextran sulfate causes severe diarrhea in AIDS patients (typically occurring after several weeks of therapy), we investigated the effect of oral dextran sulfate on mice. METHODS: Dextran sulfate (7000-8000 MW, 17-20% sulfur) was placed in the drinking water (8 mg/ml) of Swiss Webster mice. Inte
- Immunological data from an isoprinosine (immunovir) double blind, placebo controlled study.
- Int Conf AIDS. 1989 Jun 4-9;5:400 (abstract no. W.B.P.290). Unique Identifier : AIDSLINE ICA5/00201689
- S:oeberg B; Dickmeiss E; Skinb:oj P; Department of Infectious Diseases and 'Tissuetyping lab.,; University Hospital (Rigshospitalet), Copenhagen, Denmark
- OBJECTIVE: To evaluate possible differences between baseline, midway and final outcome values for mitogen-induced lymphocyte proliferation on 85 HIV-infected persons without AIDS. These persons are a one-center-subgroup of Scandinavian Isoprinosine double blind, placebo-controlled study. METHODS: PHA and PWM was used
- Intravenous immunoglobulins in adults with ARC and wr5 - a double blind longitudinal trial.
- Int Conf AIDS. 1989 Jun 4-9;5:400 (abstract no. W.B.P.291). Unique Identifier : AIDSLINE ICA5/00201789
- Schrappe-Bacher M; Rasokat H; Degenhardt S; Fatkenheuer G; Salzbeiger B; Depts. of Internal Medicine II, Pathology, Dermatology, Virology,; Med. Microbiology and Biostatistics, Univ. of Cologne, FRG
- OBJECTIVE: Evaluation of the influence of Intravenous Immunoglobulins (IVIG) on T4-cell-count and clinical status in advanced HIV 1-infection. METHODS: Inclusion-criteria were (1) less than 400 T4-cells/mul and (2) oral thrush or cutaneous anergy or (3) two clinical ARC-criteri
- Clinical efficacy of two kinds of kampo medicine on HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:400 (abstract no. W.B.P.292). Unique Identifier : AIDSLINE ICA5/00201889
- Fujimaki M; Hada M; Ikematsu S; Mori K; Takahashi H; Inagaki M; Matsuda J; Mimaya J; Sakuragauwa N; Yoshioka A; et al; Tokyo Medical College, Tokyo, Japan
- OBJECTIVE: Two kinds of Kampo Medicine (Sho-saiko-to; SST; Ninjin-to; NT) were administered to HIV infected patients in attempt to improve their immunoabnormalities. METHODS: SST or NT were administered to 56 patients whose CD4/CD8 ratio pointed below 1.0. And lymphocyte proliferation reaction, single and dual color a
- The effect of the polyene macrolide antibiotic amphotericin B and its methylated derivative (AME) on human immunodeficiency virus and phagocytosis in macrophage cultures.
- Int Conf AIDS. 1989 Jun 4-9;5:400 (abstract no. W.B.P.293). Unique Identifier : AIDSLINE ICA5/00201989
- Coye M; Pontani D; Sun D; Wolf B; Bryant P; Shahied S; Brown J; New Jersey State Department of Health, Trenton, New Jersey, USA
- The polyene antibiotic amphotericin B and its methylated derivative AME were tested in continuous macrophage cell lines for activity against HIV-1. At non-cytotoxic levels the expression of HIV-1 was inhibited as shown by the measurement of antigen with both a fluorescent and enzyme marker. At 10 ug/ml there was compl
- Activation of methionine-enkephalin (MEK): enhancement of cytotoxic T-Cells in HIV+ patients.
- Int Conf AIDS. 1989 Jun 4-9;5:400 (abstract no. W.B.P.294). Unique Identifier : AIDSLINE ICA5/00202089
- Plotnikoff NP; Miller GC; Wybran J; University of Illinois at Chicago, IL, USA
- Asymptomatic HIV+ patients were administered infusions of methionine enkephalin (MEK) at a dose of 60 mu/kg once a week for four months. Numbers of cytotoxic T-Cells CD3, CD8, CD16 and Leu19 were increased. No side effects were observed. ARC patients receiving MEK, 25-100 mu/kg, 1 to 3x a week also showed increases in
- Therapeutic effect of intravenous immunoglobulins (IVIG) in HIV infected hemophiliac children and adolescents.
- Int Conf AIDS. 1989 Jun 4-9;5:401 (abstract no. W.B.P.295). Unique Identifier : AIDSLINE ICA5/00202189
- Wagner N; Bialek R; Radinger H; Becker M; Dept. of Pediatrics, University of Bonn (FRG)
- OBJECTIVE: To evaluate the effect of long-term application of IVIG in early stages of HIV infection of hemophiliac children and adolescents. METHODS: 36 HIV infected, hemophiliac patients aged 5-20 years (median: 15 years) were enrolled in this study. Inclusion criteria were LAS, ARC or a decreased ratio of T helper c
- Long-term administration of ditiocarb in HIV-seropositive subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:401 (abstract no. W.B.P.296). Unique Identifier : AIDSLINE ICA5/00202289
- Lang JM; Kirstetter M; Livrozet JM; Touraine JL; AIDS-Imuthiol French Study Group. Strasbourg, Paris, Lyon, France
- OBJECTIVE: To assess the effects of prolonged administration of ditiocarb (Imuthiol) in HIV-seropositive subjects after double- blind, place bo-controlled short-term trial has shown both clinical and immunological benefit. METHODS: 43 consecutive HIV-infected male homosexuals entered the present open-label study on th
- Side effects of imuthiol (dithiocarb, dtc, diethyldithiocarbamate) in the therapy of early stage HIV-1 infection.
- Int Conf AIDS. 1989 Jun 4-9;5:401 (abstract no. W.B.P.297). Unique Identifier : AIDSLINE ICA5/00202389
- Reisinger E; Gottesleben A; Gotze G; Schwander S; Dorlemann A; Plettenberg A; Meigel W; Kern P; Dietrich M; Clin. Dptm. Bernhard-Nocht-Inst. for Tropical Med., Hamburg, FRG
- OBJECTIVE: We report on the side effects of DTC seen during a prospective randomized placebo-controlled double blind study in 54 HIV-positive male patients. METHODS: 13 pat. were treated orally with DTC, 14 pat. orally with placebo (10mg/kgBW once per week) and 13 pat. were treated i.v. with DTC and 14 pat. i.v. with
- Clinical evaluation of glycyrrhizin on HIV-infected asymptomatic hemophiliac patients in Japan.
- Int Conf AIDS. 1989 Jun 4-9;5:401 (abstract no. W.B.P.298). Unique Identifier : AIDSLINE ICA5/00202489
- Ikegami N; Yoshioka K; Akatani K; Osaka National Hospital, Osaka, 540 Japan
- OBJECTIVE: To evaluate the clinical effectiveness of glycyrrhizin (GL) by long-term oral administration on HIV-infected asymptomatic patients. METHODS: Glycyrrhizin is one of the biologically active components present in extract of glycyrrhizic glabra roots. The chemical structures of GL and its aglycone component, gl
- Intravenous versus oral application of pentosan-polysulfate (HOE/BAY 946) in HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:401 (abstract no. W.B.P.299). Unique Identifier : AIDSLINE ICA5/00202589
- Peter M; Ruf B; Pohle HD; II. Department of Internal Medicine, Rudolf Virchow University; Hospital (Wedding), Freie Universitat Berlin, FRG
- Pentosan-polysulfate has been shown to have HIV-1 inhibitory properties in vitro and perhaps in vivo. It is poorly absorbed through the gastrointestinal tract. Therefore, with oral application, effective intracellulare concentrations will be achieved only after a long period. This implicates high oral dosages. We perf
- Two year clinical trial with pentosan-polysulfate (HOE/BAY 946) in HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:401 (abstract no. W.B.P.300). Unique Identifier : AIDSLINE ICA5/00202689
- Bernhard R; Peters M; Schurmann D; Rubsamen-WaIgMann H; Pohle HD; Department of Internal Medicine, Rudolf Virchow University; Hospital (Wedding) Freie Universitat Berlin, FRG
- Pentosan-polysulfate has been shown to be effective against HIV-1 in vitro. We performed an open clinical pilot study with pentosan-polysulfate (HOE/BAY 946) in HIV infected patients in order to find an appropriate dosage, investigate antiviral properties, reveal possible side effects, and to determine whether subsequ
- Clinical influence of imuthiol (sodium ditiocarb) in HIV-infected patients: a review of 4 controlled studies and long-term influence.
- Int Conf AIDS. 1989 Jun 4-9;5:402 (abstract no. W.B.P.301). Unique Identifier : AIDSLINE ICA5/00202789
- Caraux J; The International AIDS Imuthiol study group (France, Germany,; USA,) Lyon France
- Between November 1983 and December 1988, more than 2,100 HIV-infected patients have been enrolled in double-blind, placebo controlled studies of Imuthiol (sodium ditiocarb, DTC). To date, results from three controlled studies in 170 ARC patients are available and results from a study in 267 ARC patients and 105 AIDS p
- Two month double blind placebo controlled trial of cyclosporin in HIV asymptomatic subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:402 (abstract no. W.B.P.302). Unique Identifier : AIDSLINE ICA5/00202889
- Aboulker JP; Andrieu JM; Gastaud JA; Debre P; Milpied-Homsi B; Groupe INSERM CICLO-T4 France
- OBJECTIVE: To evaluate, in a multicenter, double blind, placebo controlled trial, the short term effects of cyclosporin on peripheral CD4 counts. METHODS: 98 HIV asymptomatic or lymphadenopathic seropositive patients with initial CD4 counts between 300 and 600/mm3 were randomly assigned to cyclosporin 7.5 mg/kg per da
- Acute responses to ampligen infusions in HIV-infected people.
- Int Conf AIDS. 1989 Jun 4-9;5:402 (abstract no. W.B.P.303). Unique Identifier : AIDSLINE ICA5/00202989
- Pazin GJ; Huang XL; McMahon D; Armstrong JA; Rinaldo C; Ho M; Pittsburgh AIDS Clinical Trial Unit Investigators, University of; Pittsburgh, Pittsburgh, Pennsylvania, USA
- OBJECTIVE: To report our clinical and laboratory observations in HIV-infected persons associated with acute reactions during intravenous infusions of synthetic mismatched double-stranded RNA (Ampligen). METHODS: Ten acute reactions (flushing, diaphoresis, sHIVering, chills, fever and chest tightness) occurred in 3 of
- Failure of isoprinosine in prevention of ARC to AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:402 (abstract no. W.B.P.304). Unique Identifier : AIDSLINE ICA5/00203089
- Barbaro D; Fragua H; University of Texas Southwestern Medical Center at Dallas, Texas,; USA
- OBJECTIVE: To determine the effect of an immunomodulator, Isoprinosine(Inosine pranobex) in delaying the progression of disease in HIV seropositive male patients with CD4 counts of 200-400/mm3. METHODS: A prospective, multicenter, randomized, double blinded, placebo controlled clinical trial. 202 seropositive homosexu
- Neopterin and T-helper/neopterin ratio in the monitoring of long-term treatment of HIV-infected patients by imuthiol (sodium ditocarb, dtc).
- Int Conf AIDS. 1989 Jun 4-9;5:402 (abstract no. W.B.P.305). Unique Identifier : AIDSLINE ICA5/00203189
- Kirstetter M; Burkel A; Felten A; Hopital St-Antoine (Service Prof. Frottier), Laboratoire Burkel,; Institut Merieux, Paris and Lyon, France
- OBJECTIVE: To investigate whether urinary neopterin (UN) and T-helper (T4) / UN ratio correlates with prognosis in long-term therapy by Imuthiol. METHODS: 36 HIV-infected male homosexuals (age 37, range 22-45 years, weight 71 kg, range 57-84) were treated with Imuthiol (10 mg/kg once a week) for a mean duration of 17
- Timomoduline and lithium carbonate for HIV patients.
- Int Conf AIDS. 1989 Jun 4-9;5:402 (abstract no. W.B.P.306). Unique Identifier : AIDSLINE ICA5/00203289
- Buckovsky G; Popescu B; Levin C; Corrales J; Baez M; Esbivel G; Hospital Gral.San Martin; Corrientes, Argentina
- OBJECTS: It is well known the trophism of HIV, which affects the lymphocytes T4 and Monocytes; leading to immunosuppression. A study was undertaken using Timomoduline, a stimulator of lymphocytic maturation and a Granulocytic-Monocytic colony forming unit activator (GMF-CSF) and Interleukina II in vitro, Lithium Carbo
- Case report of disulfiram as first line therapy in seropositive patients attending a community clinic.
- Int Conf AIDS. 1989 Jun 4-9;5:403 (abstract no. W.B.P.307). Unique Identifier : AIDSLINE ICA5/00203389
- Davis I; Leibel J; Paroski P; Morgan A; Norris B; Woodhull Medical and Mental Health Center, Brooklyn, NY, USA
- OBJECTIVE: To use disulfiram in treatment for HIV seropositive asymptomatic patients and explore if there is a significant correlative change between T4/T8 ratio and/or absolute T4 count. METHOD: Seropositive patients with T4/T8 ratios less than 1.20 or absolute T4 counts less than 500 were started on disulfiram - a s
- Immunologic and virologic parameters in 100 HIV-infected patients (PTS) treated with isoprinosine (ISO) or placebo (PLB) as part of a multicenter phase III clinical trial.
- Int Conf AIDS. 1989 Jun 4-9;5:403 (abstract no. W.B.P.308). Unique Identifier : AIDSLINE ICA5/00203489
- Sztein M; Schulof R; Mai D; Simon G; Parenti D; Courtless J; The George Washington University Medical Center; Washington, DC,; USA
- OBJECTIVE: To provide confirmation that ISO (inosine pranobex) exhibits immunorestorative effects, and establish whether it exhibits HIV suppressive effects in a large scale double-blind placebo-controlled clinical trial. METHODS: Study Design: Randomized double-blind, placebo-controlled multicenter (19 centers in the
- Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF): a phase I trial in neutropenic AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:403 (abstract no. W.B.P.309). Unique Identifier : AIDSLINE ICA5/00203589
- Krown E; O'boyle K; Gold JW; Flomenberg N; Anselmo W; Bonnem E; Memorial Sloan-Kettering Cancer Center, New York, NY, USA
- OBJECTIVES: To evaluate the safety, efficacy and biological activity of subcutaneously (SC) administered GM-CSF in AIDS patients (pts) who were neutropenic as a result of treatment or their underlying disease. METHODS: AIDS pts with ANC less than 2000/mm3, PS greater than or equal to 60, Hb greater than or equal to 9,
- Reestablishment of a normal immunoregulatory mechanism in HIV-infected patients with immune thrombocytopenic purpura (ITP).
- Int Conf AIDS. 1989 Jun 4-9;5:403 (abstract no. W.B.P.310). Unique Identifier : AIDSLINE ICA5/00203689
- Snyder HW; Jones FR; IMRE Corporation, Seattle, WA, USA, 98109
- OBJECTIVE: To modulate activity of platelet-directed IgG (PDIgG) and circulating immune complexes (CIC) by PROSORBA column treatment of plasma from patients with ITP. METHODS: Ninety-seven patients with chronic ITP (39 patients with HIV infection) received 4-8 treatments, involving adsorption of 250-2000 ml plasma, wi
- Amelioration of deteriorated polymorphonuclear leukocyte (PMN) phagocyte function of hemophiliacs with HIV infection by administration of long-term polysaccharide immunopotentiator (lentinan).
- Int Conf AIDS. 1989 Jun 4-9;5:403 (abstract no. W.B.P.311). Unique Identifier : AIDSLINE ICA5/00203789
- Matsuda J; Gohchi K; Kinoshita T; Abe T; Department of Medicine, Teikyo University School of Medicine,; Tokyo, Japan
- OBJECTIVE: PMN phagocytic function (PMN-PF) of hemophiliacs (H) was evaluated in vitro and the effect of long-term treatment with lentinan on impaired PMN-PF was studied. METHOD: PMN-PF of 39 H, including 22 cases with HIV infection, was measured as the intensity of PMN chemiluminescence (PMN-CL) evolved from PMN when
- An open label dose-ranging trial of al721 in pgl and ARC.
- Int Conf AIDS. 1989 Jun 4-9;5:403 (abstract no. W.B.P.312). Unique Identifier : AIDSLINE ICA5/00203889
- Mildvan D; Armstrong D; Antoniskis D; Sacks H; Balfour H; Buzas J; Pettinelli C; Beth Israel Med. Cent. NY, USA
- OBJECTIVE: To assess the safety and tolerance of escalating doses of AL721, a lipid compound with reported anti-HIV activity via cell membrane or virion cholesterol depletion. METHODS: The study was a multi-center open label dose-ranging trial in patients with PGL and ARC. AL721 was administered for 8 weeks at 20, 30,
- Inosine pranobex therapy in HIV seropositive patients at risk of developing AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:404 (abstract no. W.B.P.313). Unique Identifier : AIDSLINE ICA5/00203989
- Murphy R; Von Roenn J; Pottage J; Williams L; Benson C; Kessler H; Phair J; Northwestern University Medical School and Rush Medical College,; Chicago, IL USA
- Inosine Pranobex (ISO), a synthetic immunopotentiating agent, was administered orally in a prospective, placebo-controlled, randomized, double-blind trial to 122 HIV seropositive, non-AIDS, male patients(pts) with an absolute CD4 count between 200-400 cells/mm3 at entry. Objectives were to determine whether ISO can de
- Effect of passive immunization in patients with ARC and AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:404 (abstract no. W.B.P.314). Unique Identifier : AIDSLINE ICA5/00204089
- Karpas A; Hill F; Youle M; Gray J; Oates JK; Gazzard B; Dept. of Haemotology, University of Cambridge Clinical School, UK
- OBJECTIVE: To determine the benefits of passive immunization in ARC and AIDS. METHODS: Plasma was collected from healthy HIV positive donors who had high titers of antiviral antibodies as monitored in the Karpas cell test. Beta-propiolactone was used to inactivate viruses. ARC and AIDS patients received monthly transf
- A phase I/II dose ranging trial of oral dextran sulfate in HIV p24 antigen positive individuals (ACTG 060): results of a safety and efficacy trial.
- Int Conf AIDS. 1989 Jun 4-9;5:404 (abstract no. W.B.P.315). Unique Identifier : AIDSLINE ICA5/00204189
- Abrams D; Pettinelli C; Power M; Kubacki VB; Grieco MH; Henry WK; NIAID AIDS Program, Bethesda, Maryland, USA
- OBJECTIVE: To evaluate the long-term toxicity, establish the maximally tolerated dose (MTD) and evaluate the antiretroviral activity of oral dextran sulfate (DS) (MW 7,000-8,000, 17-20% sulfur, Uendex) in HIV p24 antigen positive patients. METHODS: A multi-center unblinded 6 month trial of at least 2 doses of DS was d
- [Effects of MM1 on AIDS patients]
- Int Conf AIDS. 1989 Jun 4-9;5:404 (abstract no. W.B.P.316). Unique Identifier : AIDSLINE ICA5/00204289
- Lurhuma Z; Shafik A; Diese M; Wane J; Tshiamala K; Bimamisana B; Kinshasa, Zaire
- Use of Zidovudine in injection drug use (IDU) related HIV infection - drug compliance and clinic attendance.
- Int Conf AIDS. 1989 Jun 4-9;5:404 (abstract no. W.B.P.317). Unique Identifier : AIDSLINE ICA5/00204389
- Cowan FM; Jones ME; Flegg PJ; MacCallum LR; Brettle RP; Gray JA; Infectious Diseases Unit, City Hospital, Edinburgh. UK
- OBJECTIVE: The evaluation of drug compliance and clinic attendance in Zidovudine treatment of injection drug use related HIV infection (IDUHIV). METHOD: 322 HIV seropositives were assessed at the City Hospital, of which 253 (79%) were infected between 1983-85 by IDU. Of 51 treated with Zidovudine, 37 were male (22 IDU
- Effectiveness of low-dose-combination therapy with azidothymidine (Zidovudine) and acyclovir in AIDS- and ARC-patients.
- Int Conf AIDS. 1989 Jun 4-9;5:404 (abstract no. W.B.P.318). Unique Identifier : AIDSLINE ICA5/00204489
- Walger PP; Baumgart G; Wilke G; Kupfer U; Schwaaf A; Dorst KG; Mediziniscne Poliklinik, University of Munster FRG
- OBJECTIVE: Examination of effectiveness of AZT /ACV low-dose therapy in regard to clinical, virological and immunological parameters in AIDS- and ARC-patients. METHODS: Open prospective study of 54 patients (19 AIDS, WR6; 35 ARC, WR 4-5) receiving low-
- Allogenic bone marrow transplantation (BMT) plus azidothymidine (AZT) in an AIDS patient with non-Hodgkin's lymphoma (NHL).
- Int Conf AIDS. 1989 Jun 4-9;5:405 (abstract no. W.B.P.319). Unique Identifier : AIDSLINE ICA5/00204589
- Holland HK; Rossi JJ; Donnenberg AD; Zaia JA; Santos GW; Saral R; The Johns Hopkins University, Baltimore, MD, USA
- OBJECTIVE: To evaluate the effect of combined modality therapy ( AZT plus allogeneic BMT) on HIV-1 infection in a lymphoma patient with AIDS. METHODS: The patient, a 41 yo HIV-1 culture+ man with NHL, received cyclophosphamide and total body irradiatio
- As 101 in association with azt in AIDS patients: a phase I pilot study.
- Int Conf AIDS. 1989 Jun 4-9;5:405 (abstract no. W.B.P.320). Unique Identifier : AIDSLINE ICA5/00204689
- Laporate JP; Frottier J; Dormont D; Imbert JC; Albeck M; Najman A; St Antoine Cooperative Group on AIDS, 75012, Paris, France
- Interesting clinical and biological results have been obtained with AS 101 (a new immunomodulating agent, Nature 1987,330: 173-176) in AIDS patients. However in an effort to further improve patients with advanced disease, we tried to associate AZT wit
- Effect of combination of Zidovudine and interferon-alpha compared with Zidovudine and acyclovir on HIV-antigenaemia in asymptomatic patients.
- Int Conf AIDS. 1989 Jun 4-9;5:405 (abstract no. W.B.P.321). Unique Identifier : AIDSLINE ICA5/00204789
- Weber R; Bonetti A; Luthy R; Putzi R; Spacey B; Siegenthaler W; Department of Medicine, University Hospital, Zurich, Switzerland
- OBJECTIVE: To assess the antiretroviral effect of Zidovudine ( AZT ) in combination with either lymphoblast interferon-alpha (INF) or acyclovir (ACV) in asymptomatic HIV infected pts. METHODS: 15 pts in CDC stage
- Zidovudine vs. alpha interferon vs. the combination in patients with early HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:405 (abstract no. W.B.P.322). Unique Identifier : AIDSLINE ICA5/00204889
- Zunich KM; Davey V; Metcalf JA; Masur H; Fauci AS; Lane HC; National Institutes of Health, Bethesda, MD, USA
- OBJECTIVE: To compare the effects of Zidovudine ( AZT ), alpha interferon (alpha IFN), and a combination of these 2 drugs in delaying the progression of HIV disease. METHODS: HIV-infected persons with greater than 500 CD4+ cells/mm3 and no history of op
- An open-label study of the safety and efficacy of co-administration of Zidovudine and recombinant ifn-beta.
- Int Conf AIDS. 1989 Jun 4-9;5:405 (abstract no. W.B.P.323). Unique Identifier : AIDSLINE ICA5/00204989
- Borucki MJ; Pollard R B; Division of Infectious Diseases, University of Texas Medical; Branch at Galveston, USA
- OBJECTIVE: A phase I study of the long-term tolerance of recombinant interferon-beta-ser (Betaseron) at doses of 45 or 90 million units when administered subcutaneously on a daily basis to HIV-infected individuals receiving 200 mg of Zidovudine (ZDV) every four hours. METHODS: Seventeen patients who had previously bee
- Effect of a combined dextranesulfate/Zidovudine therapy compared to Zidovudine monotherapy in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:405 (abstract no. W.B.P.324). Unique Identifier : AIDSLINE ICA5/00205089
- Brockmeyer NH; Mertins L; Goos M; Dept. of Dermatology, University of Essen, FRG
- 18 HIV infected patients (status WR 6) were randomly attached to a combined dextranesulfate (1800 mg/d)/ Zidovudine (800 mg/d) therapy (DZ) or a Zidovudine (800 mg/d) monotherapy (Z). Each group consisted of 9 patients, age 23 to 35 years, with equivalent amounts of CD4+ lymphocytes in both groups prior to therapy. Be
- The safety of Zidovudine and interleukin 2 in asymptomatic HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:406 (abstract no. W.B.P.325). Unique Identifier : AIDSLINE ICA5/00205189
- Bartlett JA; Blankenship KD; Greenberg M; Tyler DS; Weinhold KJ; Duke University Medical Center, Durham, NC, USA
- OBJECTIVE: To study the safety of combining Zidovudine (ZDV) and interleukin 2 (IL2) in patients with asymptomatic HIV infection. METHODS: Patients with WR2 HIV infection were given ZDV 200 mg po 5x/day for 8 wks, 4 wks of both ZDV and 100,000 u/m2 IL2 qd, and finishing with 8 wks of ZDV alone. Four patients have comp
- Combined treatment with Zidovudine and lymphoblast interferon alpha in patients with HIV-related kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:406 (abstract no. W.B.P.326). Unique Identifier : AIDSLINE ICA5/00205289
- Baumann R; Department of Medicine, University Hospital of Zurich,; Switzerland
- OBJECTIVE: To assess efficacy and side effects of combination therapy with low dose Zidovudine ( AZT ) and lymphoblast interferon alpha (IFN) in patients (pts) with AIDS-related Kaposi s sarcoma (KS). ME
- Long-term (18 month) treatment of severe HIV infection with an alternating regimen of AZT and 2',3'-dideoxycytidine (DDC).
- Int Conf AIDS. 1989 Jun 4-9;5:406 (abstract no. W.B.P.327). Unique Identifier : AIDSLINE ICA5/00205389
- Yarchoan R; Pluda JM; Thomas RV; Perno CF; McAtee N; Broder S; Clinical Oncology Program, National Cancer Institute, Bethesda,; Maryland, USA
- OBJECTIVE: AZT and ddC are 2 pyrimidine dideoxynucleosides (ddN) with activity against HIV and different limiting toxicities. AZT can cause bone marrow suppression, while continuous high-dose ddC can cause painful
- Daily subcutaneous recombinant granulocyte-macrophage colony stimulating factor improves the neutropenia induced by azidothymidine in patients with AIDS/ARC; follow-up.
- Int Conf AIDS. 1989 Jun 4-9;5:406 (abstract no. W.B.P.328). Unique Identifier : AIDSLINE ICA5/00205489
- Levine JD; Allan JD; Tessitore JH; Falcone N; Israel R; Groopman JE; New England Deaconess Hospital, Harvard Medical School, Boston,; MA 02215
- OBJECTIVE: To determine safety and efficacy of subcutaneous recombinant Granulocyte-Macrophage Colony Stimulating Factor in patients with AZT induced Neutropenia. METHODS: We have studied the use of once daily subcutaneous (GM-CSF) in 17 patients who
- The use of an alternating regimen of AZT and subcutaneous (SC) gm-csf in patients with severe HIV infection and leukopenia.
- Int Conf AIDS. 1989 Jun 4-9;5:406 (abstract no. W.B.P.329). Unique Identifier : AIDSLINE ICA5/00205589
- Pluda JM; Yarchoan Y; McAtee N; Thomas; Oette D; Broder S; NCI, Bethesda Md, USA
- OBJECTIVE: To evaluate the toxicity and activity of an alternating regimen of AZT and GM-CSF in patients (pts) with severe HIV infection and leukopenia. METHODS: SC GM-CSF was administered to four pts who had used prior AZT and 5 who had not on a cont
- Augmentation of non-mhc restricted cellular cytotoxicities in patients receiving Zidovudine plus interleukin 2.
- Int Conf AIDS. 1989 Jun 4-9;5:406 (abstract no. W.B.P.330). Unique Identifier : AIDSLINE ICA5/00205689
- Weinhold K; Tyler D; Austin A; Lyerly K; Bolognesi D; Bartlett J; Duke University Medical Center, Durham, NC, USA
- OBJECTIVE: To correct defects in cellular cytotoxicities among asymptomatic HIV-1 infected individuals by administration of IL-2 . METHODS: Patients entered onto ACTG Protocol 042 received 200mg Zidovudine (ZDV) orally 5 times daily for 21 weeks. During weeks 9-12, pati
- Zidovudine (AZT) treatment of the AIDS dementia complex (ADC): results of a placebo-controlled, multicentered therapeutic trial.
- Int Conf AIDS. 1989 Jun 4-9;5:407 (abstract no. W.B.P.331). Unique Identifier : AIDSLINE ICA5/00205789
- Price RW; Koch MA; Sidtis JJ; Feinberg J; Collier A; Kennedy C; Singer E; Price S; AIDS Clinical Trials Group, NIAID, Bethesda, MD, USA
- OBJECTIVE: To determine the efficacy of AZT in alleviating mild to moderate ADC in HIV-1-infected patients with relatively preserved CD4+ cells. METHODS: 40 patients with mild to moderate ADC from 9 centers were randomized to 3 treatment arms: AZT 400
- Study compliance among asymptomatic HIV seropositives (ASX HIV+) being treated with azidothymidine (AZT).
- Int Conf AIDS. 1989 Jun 4-9;5:407 (abstract no. W.B.P.332). Unique Identifier : AIDSLINE ICA5/00205889
- Jacobsen PB; Vassalos C; Brown D; Gorfinkle K; Philogene G; Polsky B; Memorial Sloan-Kettering Cancer Center, New York, New York, USA
- OBJECTIVE: To measure compliance and identify factors related to degree of compliance among participants in an experimental trial of the efficacy of AZT in preventing/slowing the development of AIDS. METHODS: Twenty (19 male, 1 female) ASX HIV+ enroll
- Survival of patients with HIV disease treated with Zidovudine (AZT).
- Int Conf AIDS. 1989 Jun 4-9;5:407 (abstract no. W.B.P.333). Unique Identifier : AIDSLINE ICA5/00205989
- Shepp D; Kaplan M; Muggeo C; Smith M; Lesser M; Cornell U. Medical College, North Shore U. Hospital, Manhasset,; NY, USA
- OBJECTIVE: To determine the probability of survival in patients with HIV disease treated with Zidovudine ( AZT ). METHODS: From 11/86 through 12/87, patients meeting current USFDA indications for treatment received AZT. Initial dose used was 1-1.2g/day
- Reduction of Zidovudine side effects by an intermittent therapy scheme.
- Int Conf AIDS. 1989 Jun 4-9;5:407 (abstract no. W.B.P.334). Unique Identifier : AIDSLINE ICA5/00206089
- Staszewski S; Odewald J; Gottstein A; Rehmet S; Helm EB; Stille W; Universitatsklinik Frankfurt, Zentrum der Inneren Medizin,; Infektions-Ambulanz. FRG
- In a dosage from 1000 - 1200 mg/d. Zidovudine ( AZT ), in spite of its life prolonging effect, causes myelotoxic side effects. By an intermittent therapy scheme with a drug-free regeneration period, these side effects on hematopoesis might be avoided. W
- A phase I/II trial of the combination of Zidovudine and interleukin-2 in the treatment of HIV-related Kaposi's sarcoma.
- Int Conf AIDS. 1989 Jun 4-9;5:407 (abstract no. W.B.P.335). Unique Identifier : AIDSLINE ICA5/00206189
- Kovacs A; Davey R; Polis M; Zunich K; Fauci AS; Lane HC; National Institutes of Health, Bethesda, Maryland, USA
- OBJECTIVE: To evaluate the toxicity and efficacy of the combination of Zidovudine and interleukin-2 in the treatment of HIV-infected patients with Kaposi s sarcoma. METHODS: In an open study, patients with HIV infection documented by ELISA, Western blot, or culture, and biopsy-documented Kaposi s sarcoma were begun on
- Zidovudine use in intravenous drug users.
- Int Conf AIDS. 1989 Jun 4-9;5:407 (abstract no. W.B.P.336). Unique Identifier : AIDSLINE ICA5/00206289
- Slim J; Perez G; Forrester C; Tonnesen G; Johnson ES; Saint Michael's Medical Center, Newark, New Jersey, USA
- OBJECTIVE: To describe characteristics and effects of Zidovudine usage in an intravenous drug user population. METHODS: A retrospective review of 43 patients studied from 2/87 through 7/88 who were followed bi-weekly in a clinic environment with complete cell counts (CBC) chemistry profiles and physical examinations.
- Outcomes of treatment with AZT of patients with AIDS and symptomatic HIV infection (ARC).
- Int Conf AIDS. 1989 Jun 4-9;5:408 (abstract no. W.B.P.337). Unique Identifier : AIDSLINE ICA5/00206389
- Cox P; Martin M; Styer C; Beall GN; MD Dept Med, Harbor-UCLA Med Ctr, Torrance, CA, USA
- OBJECTIVE: To assess the effectiveness of AZT and the incidence of hematological toxicity in a standard clinical practice. METHOD: A retrospective chart review of 101 patients with AIDS (73%) and ARC (27%) treated with AZT at a public hospital clinic
- AZT Therapy in infected people: efficacy and side effects.
- Int Conf AIDS. 1989 Jun 4-9;5:408 (abstract no. W.B.P.338). Unique Identifier : AIDSLINE ICA5/00206489
- Chiodo F; Costigliola P; Ricchi E; Borderi M; Manfredi R; Guariento A; Boni P; Istituto Malattie Infettive; Universita di Bologna, Italy
- OBJECTIVE: To study the efficacy and toxicity of long term administration of Zidovudine ( AZT ). METHODS: From August 1987 to December 1988, 48 HIV Ab+ve subjects with various clinical features (5 0I-AIDS, 2 SK-AIDS, 27 ARC-CDC IVa, 14 SF/PGL (WR5) were
- Zidovudine treatment of HIV infection: clinical & immunological evaluation.
- Int Conf AIDS. 1989 Jun 4-9;5:408 (abstract no. W.B.P.339). Unique Identifier : AIDSLINE ICA5/00206589
- Valencia ME; Rodriguez MC; Lavilla P; Pintado V; Gil A; Vazquez JJ; Hospital La Paz Madrid, Spain
- OBJECTIVE: To evaluate the effect of Zidovudine in HIV infection. METHODS: 33 HIV-patients were included: 24 with AIDS and 9 with ARC. Mean age was 30 y (r:24-59). There were 24 IV drug abusers, 5 homosexuals, 2 bisexuals and 1 heterosexual contact. The A
- Zidovudine (AZT) treatment in AIDS and ARC.
- Int Conf AIDS. 1989 Jun 4-9;5:408 (abstract no. W.B.P.340). Unique Identifier : AIDSLINE ICA5/00206689
- Raise E; Vannini V; Schiattone ML; Pulsatelli L; Gualandi G; Cicognani A; Procaccio L; Martuzzi M; Dip. Infectious Diseases and Immunopathology Unit, Clinical; Pathology, Maggiore Hospital, Bologna, Italy
- OBJECTIVE: To evaluate efficacy of AZT (2.8mg/kg/q4h) on lymphocyte subset and antigenaemia (HIV1Ag) in an open controlled trial. METHODS: The study concerns 58 AIDS with Candida Esophagitis, P. Carinii pneumonia, chronic mucocutaneous ulcers due to H
- Neurological and immunological evaluation of a patient treated with AZT with acute HIV infection and encephalopathy.
- Int Conf AIDS. 1989 Jun 4-9;5:408 (abstract no. W.B.P.341). Unique Identifier : AIDSLINE ICA5/00206789
- Zangerle R; Pohl P; Felber S; Fritsch P; Dept of Dermatology, University of Innsbruck, Innsbruck, Austria
- OBJECTIVE: We describe a 30-year-old patient with signs of acute HIV infection treated with AZT because of persistent neurological dysfunction. METHODS: HIV serology, CD4 count, neopterin, B2 microglobulin, delayed hypersensitivity, MRI and neuropsych
- Follow up and treatment of 58 HIV-infected patients in Greece.
- Int Conf AIDS. 1989 Jun 4-9;5:408 (abstract no. W.B.P.342). Unique Identifier : AIDSLINE ICA5/00206889
- Stergiou GD; Ploumidis GM; Papadopoulos AI; Roumeliotou AN; Georgopoulou SA; Papaevangelou GL; 1st IKA Hospital, Athens, Greece
- OBJECTIVE: To present our experience from the follow up and treatment of 58 patients with HIV-infection in Greece . METHOD: 58 patients with AIDS or ARC were studied, according to their clinical and laboratory findings, their CDC cla
- Update on AZT therapy in an inner city population.
- Int Conf AIDS. 1989 Jun 4-9;5:409 (abstract no. W.B.P.343). Unique Identifier : AIDSLINE ICA5/00206989
- Samuels J; Hendrix J; Hilton M; Sloan V; Small CB; North Central Bronx Hospital, Bronx, New York, NY, USA
- OBJECTIVE: To evaluate efficacy, toxicity and compliance (comp) with AZT therapy among patients (pts) of poor, minority and intravenous drug use (IVDU) background in a clinic in New York City. METHODS: Prospective data was derived on all AIDS and ARC
- [Outcome of 365 patients with AIDS or ARC and treated with AZT for 4 to 18 months]
- Int Conf AIDS. 1989 Jun 4-9;5:409 (abstract no. W.B.P.344). Unique Identifier : AIDSLINE ICA5/00207089
- Dournon E; Matheron S; Rozenbaum W; Michon C; Perronne C; et Groupe D'Etude de l'AZT. Hopital Claude Bernard, Paris, France
- Experience with Zidovudine in a city hospital AIDS clinic.
- Int Conf AIDS. 1989 Jun 4-9;5:409 (abstract no. W.B.P.345). Unique Identifier : AIDSLINE ICA5/00207189
- Miller L; Peterson K; Davidson A; Cohn D; Denver Disease Control Service, Denver, CO, USA
- OBJECTIVE: To evaluate the efficacy and toxicity of Zidovudine ( AZT ) in patients (pts) with AIDS and ARC at Denver Department of Health and Hospitals (DHH). METHODS: A retrospective chart review of clinic and hospital records at DHH was done for all p
- Effects of Zidovudine different dose regimens on clinical, immunological and virological indices of ARC patients followed for one year.
- Int Conf AIDS. 1989 Jun 4-9;5:409 (abstract no. W.B.P.346). Unique Identifier : AIDSLINE ICA5/00207289
- Cuneo-Crovari P; Cassola G; Crovari P; Guida B; Icardi GC; Piersantelli N; Inst Hyg Prev Med, Univ of Genoa, Italy
- OBJECTIVE: The aim of this study was to assess the progression of clinical symptoms and laboratory indices in HIV infected patients (intravenous drug users = IVDU) who received Zidovudine for 12 months at least in different dose regimens with or without Acyclovir in comparison w
- Benefits of AZT when started at increasing times after AIDS/PCP diagnosis.
- Int Conf AIDS. 1989 Jun 4-9;5:409 (abstract no. W.B.P.347). Unique Identifier : AIDSLINE ICA5/00207389
- Nightingale SD; Pounders SM; Orcutt V; Collins S; Jockusch JD; Parkland Memorial Hospital, Dallas, TX, USA
- The survival of 172 patients who had PCP at AIDS diagnosis and received AZT was compared, by a retrospective case control analysis, to survival of 149 controls who had PCP at AIDS diagnosis but never received AZT. Case survival was calculated from day
- Progression of HIV infected hemophilias under AZT treatment one year follow up study.
- Int Conf AIDS. 1989 Jun 4-9;5:409 (abstract no. W.B.P.348). Unique Identifier : AIDSLINE ICA5/00207489
- Mandalaki T; Karafoulidou A; Gialeraki A; Economidou J; Makris P; Potamianou A; Psarra K; Laiken Hosp. Athens, Greece
- OBJECTIVE: To evaluate the tolerance, safety and effectiveness of Zidovudine ( AZT ) treatment according to the clinical stage (Walter-Reed system) at the beginning of the treatment. METHOD: 15 HIV (+) Hemophiliacs aged 17-62 years, classified to WR 3,4
- Zidovudine (AZT) in HIV positive haemophiliacs.
- Int Conf AIDS. 1989 Jun 4-9;5:410 (abstract no. W.B.P.349). Unique Identifier : AIDSLINE ICA5/00207589
- Lim SG; Lee CA; Hales M; Giangrande P; Kernoff PB; Haemophilia Centre and Haemostasis Unit, Academic Department of; Haematology, Royal Free Hospital, London, United Kingdom
- OBJECTIVE: To review the effect of Zidovudine in HIV positive haemophiliacs. METHODS: A retrospective analysis of 21 patients treated with Zidovudine at the Haemophilia Centre of the Royal Free Hospital was performed. .14 were CDC IV, 1 was CDC III with thrombocytopenia, 4 had oral candidiasis, and 2 were CDC II but e
- Zidovudine therapy in homosexual/bisexual patients with AIDS-related complex (ARC) in Australia.
- Int Conf AIDS. 1989 Jun 4-9;5:410 (abstract no. W.B.P.350). Unique Identifier : AIDSLINE ICA5/00207689
- Swanson CE; Cooper DA; NHMRC Special Unit in AIDS Epidemiology and Clinical Research,; University of New South Wales, Sydney, NSW, Australia
- OBJECTIVES: To monitor the efficacy, toxicity and safety of Zidovudine (ZDV) therapy in patients with AIDS-related complex (ARC) in a multi-centre clinical trial in Australia . METHODS: Patients with ARC have been enrolled in the study since June, 1987. By June 1988, 301 homosexu
- Cessation of Zidovudine (AZT) therapy leads to increased frequency of viral isolation.
- Int Conf AIDS. 1989 Jun 4-9;5:410 (abstract no. W.B.P.351). Unique Identifier : AIDSLINE ICA5/00207789
- Wainberg MA; Fanning M; Gill J; Gelmon K; Montaner JS; O'Shaughnessy M; Tsoukas C; Ruedy J; Jewish General Hospital, Montreal, Quebec, Canada
- OBJECTIVE: To carry out a dose-finding-toxicity study on 72 HIV-infected adults (CDC stages II and III) and to assess viral burden in such individuals. METHODS: HIV-1 was isolated from the circulating mononuclear cells of each subject at regular intervals throughout the study. Subjects received 600 mg drug per day for
- Improvement of survival in AIDS patients with Zidovudine therapy.
- Int Conf AIDS. 1989 Jun 4-9;5:410 (abstract no. W.B.P.352). Unique Identifier : AIDSLINE ICA5/00207889
- Arici C; Rizzi M; Finazzi MG; Minola E; Department of Infectious Diseases, Ospedali Riuniti, Bergamo,; Italia
- OBJECTIVE: To compare survival after AIDS diagnosis, in patients admitted to our department before and after the introduction of Zidovudine therapy. METHODS: We evaluated survival after the diagnosis of AIDS (Kaplan-Meier method) during 1985-1986-1987 (before Zidovudine became available at our department) and in 1988
- Efficacy of AZT in a municipal hospital clinic.
- Int Conf AIDS. 1989 Jun 4-9;5:410 (abstract no. W.B.P.353). Unique Identifier : AIDSLINE ICA5/00207989
- Cohn J; McMeeking A; Schlamm H; Vogler M; Allen S; Holzman R; New York University-Bellevue Hospital, New York, New York, USA
- OBJECTIVE: To evaluate survival of AIDS and ARC patients treated with Zidovudine ( AZT ) at a municipal hospital clinic. METHODS: Patients (pts) eligible for AZT under the Treatment IND or the FDA s licensed indications were treated in a specially desig
- The effect of Zidovudine (AZT) on survival of AIDS patients in San Francisco.
- Int Conf AIDS. 1989 Jun 4-9;5:410 (abstract no. W.B.P.354). Unique Identifier : AIDSLINE ICA5/00208089
- Lemp GF; Payne SF; Neal DP; Rutherford GW; San Francisco Department of Public Health, San Francisco, CA, USA
- OBJECTIVE: To evaluate the effect of Zidovudine ( AZT ) on survival trends for AIDS patients diagnosed in San Francisco (SF) in 1986 and 1987. METHODS: Information on antiviral therapy was available for 668 (25%) of 2,723 AIDS patients diagnosed in 1986
- Zidovudine (AZT), preventive treatment of AIDS in HIV seropositive patients?
- Int Conf AIDS. 1989 Jun 4-9;5:411 (abstract no. W.B.P.355). Unique Identifier : AIDSLINE ICA5/00208189
- Tourani JM; Stern M; Volstein M; Lowenstein W; Andrieu JM; Laennec Hospital, 42 rue de Sevres - 75340 Paris Cedex 07-France
- To assess the efficacy of Zidovudine ( AZT ) in the prevention of AIDS we conducted, in September 1987, an open study in 76 non AIDS/HIV seropositive patients with a low T4 cell count (CD4 greater than 300/ul). 39 patients (group I) received AZT (20 mg/
- Open trial of the long-term safety of Zidovudine - interim analysis.
- Int Conf AIDS. 1989 Jun 4-9;5:411 (abstract no. W.B.P.356). Unique Identifier : AIDSLINE ICA5/00208289
- Houle L; Peake J; Fletcher M; Burroughs Wellcome Inc., Kirkland, Quebec, Canada
- OBJECTIVE: To present an interim safety analysis of this ongoing Canadian Open Trial of the Long-Term Safety of Zidovudine. METHODS: There are 9 provincial study centres in Canada . Follow up is required on each patient entered every 2 weeks for the first 2 months and then once ever
- Disease status and HIV isolate replication in 31 haemophiliacs including 11 AZT treated patients.
- Int Conf AIDS. 1989 Jun 4-9;5:411 (abstract no. W.B.P.357). Unique Identifier : AIDSLINE ICA5/00208389
- Elio B; Mori PG; Franchine E; Lanza T; Ferrari G; Varnier OE; Dept Haemotology & Oncology, Geneva, Italy
- OBJECTIVE: Correlation of disease status to the replicative properties of HIV isolates in 31 infected haemophiliacs including 11 AZT treated patients. METHODS: 31 haemophiliacs contracted HIV infection between 1980 and 1984; at present, 10 are classif
- Major opportunistic infections in AIDS patients after eight to one hundred fifty weeks of Zidovudine therapy.
- Int Conf AIDS. 1989 Jun 4-9;5:411 (abstract no. W.B.P.358). Unique Identifier : AIDSLINE ICA5/00208489
- Causey DM; Leedom JM; Melancon H; University of Southern California, Los Angeles, CA, USA
- OBJECTIVE: To describe the incidence and types and outcomes of AIDS-defining opportunistic infections (OI s) in patients treated with ZDV for 8-150 weeks. METHODS: Twenty-two patients with previous Pneumocystis Carinii pneumonia (PCP) were enrolled. Nineteen of the 22 completed more than 8 weeks of ZDV therapy. Eleven
- An open trial of Zidovudine (AZT) in 17 zairian patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:411 (abstract no. W.B.P.359). Unique Identifier : AIDSLINE ICA5/00208589
- Kapita B; Milangu M; Nyst M; Musongela K; Chalhoub E; Ryder R; Mama Yemo Yemo Hospital, Zaire
- OBJECTIVE: To observe the clinical efficacy of AZT in African patients with AIDS hospitalized at Mama Yemo Hospital (MYH), Kinshasa, Zaire . METHODS: Between March and December, 1988, at MYH, 17 patients with AIDS
- Zidovudine delays development of AIDS for patients with 4c-2, 3 and 4a HIV disease.
- Int Conf AIDS. 1989 Jun 4-9;5:411 (abstract no. W.B.P.360). Unique Identifier : AIDSLINE ICA5/00208689
- Rachlis A; Bonner M; Fletcher M; Houle L; Sunnybrook Medical Centre and the University of Toronto, Toronto,; Ontario, Canada
- OBJECTIVE: To establish drug use patterns and the rate of progression to AIDS in a group of 4C-2, 3 and 4A patients treated with Zidovudine. METHOD: A group of patients was followed for at least 6 months in the Ontario Canada open Zidovudine treatment study: 136 4C-2 patients, 67 c
- Treatment with retrovir in different stages of the HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:412 (abstract no. W.B.P.361). Unique Identifier : AIDSLINE ICA5/00208789
- Maio G; Izzo CM; Manzillo E; Buonocore S; Manzillo G; D. Cotugno Hospital -USL 41- Napoli - Italy
- 54 HIV-Ab positive patients (6 of II group, 13 of III group, 35 of IV group of CDC classification) received AZT in doses of 1200mg/die for 6-20 months: 48 of these patients (89%) were drug abusers (d.a.); 16 of then (33%) resulted dropped out (d.o.) d
- Efficacy and tolerance of Zidovudine in patients with asymptomatic HIV infections or with pgl.
- Int Conf AIDS. 1989 Jun 4-9;5:412 (abstract no. W.B.P.362). Unique Identifier : AIDSLINE ICA5/00208889
- Chirianni A; Cataldo PT; Noce S; Bonadies G; Picciotto L; Piazza M; Clinic of Infectious Diseases University Naples-Italy
- OBJECTIVE: Evaluation of the effects and tolerance of Zidovudine (ZDV) in HIV seropositive patients. METHODS: 10 asymptomatic patients (CDC group II) and 10 with PGL (CDC group III) all with initial T4 counts ranging between 150 and 300/mmc were given ZDV 7 mg/Kg for 4 times a day for the first month and 3.5 mg/Kg for
- Long term assessment of toxicity and clinical outcome in treatment of HIV infection with Zidovudine.
- Int Conf AIDS. 1989 Jun 4-9;5:412 (abstract no. W.B.P.363). Unique Identifier : AIDSLINE ICA5/00208989
- Dyner T; Lang W; Geaga J; Bender J; AIDS Clinical Research Project, Children's Hospital of San; Francisco, California, USA
- OBJECTIVE: To evaluate the toxicity and assess the long term clinical outcome of Zidovudine therapy in HIV infected individuals diagnosed with AIDS or who have been symptomatic with less than 200 CD4 cells. METHODS: A prospective, open- ended uncontrolled study of Zidovudine therapy began in December of 1986. By the e
- Zidovudine treatment in 100 consecutive patients with AIDS or AIDS related complex.
- Int Conf AIDS. 1989 Jun 4-9;5:412 (abstract no. W.B.P.364). Unique Identifier : AIDSLINE ICA5/00209089
- Roudot F; Hargous ML; Sobel A; Cassinat B; Rekacewicz I; Lyonnet F; Hopital Henri Mondor, 94010 Creteil, France
- OBJECTIVE: To analyse Zidovudine treatment in severe HIV infection in terms of survival, toxicity and dose maintenance. METHODS: 100 consecutive patients with AIDS and ARC received Zidovudine at a starting dose of 600-1200 mg per day. The drug was always given orally every 6 hours. The patients comprised 55 AIDS patie
- Correlation between p24 antigenaemia and cd4+/neopterin ratio in AZT-treated patients.
- Int Conf AIDS. 1989 Jun 4-9;5:412 (abstract no. W.B.P.365). Unique Identifier : AIDSLINE ICA5/00209189
- Crocchiolo P; Lizioli A; Panzeri MP; Filippi C; Arcidiacono I; Nardella ML; Ospedale Maggiore - 20075 LODI, Italy
- OBJECTIVE: To verify whether CD4+/neopterin ratio (R) correlates with clinical course and p24 Antigenaemia (p24Ag) in AZT-treated patients infected with HIV. METHODS: 14 HIV-positive pts (10 males, 4 females, mean age 24.3, range 20-32 years; 6 p24Ag pos., 8 p24Ag neg. at enrollment) were daily administered 18 mg/Kg A
- [Clinical and biological surveillance of 108 patients treated with zidovudine during a period of 12 to 18 months]
- Int Conf AIDS. 1989 Jun 4-9;5:412 (abstract no. W.B.P.366). Unique Identifier : AIDSLINE ICA5/00209289
- Boillot C; Pesce A; Quaranta JF; Vinti H; Taillan B; Cassuto JP; C.H.R.U. de Nice, France
- AZT therapy in intravenous drug users (IVDU'S) and their sexual partners.
- Int Conf AIDS. 1989 Jun 4-9;5:413 (abstract no. W.B.P.367). Unique Identifier : AIDSLINE ICA5/00209389
- Spears A; Landesman S; Shafer R; Chirgwin K; Dehovitz J; Kings County Hospital Center and SUNY - Health Science Center at; Brooklyn, USA
- OBJECTIVE: Describe the experience of our clinic in administering AZT to IVDU s and to sexual partners of IVDU s. METHODS: 59 consecutive pts who were IVDU s or who were sexual partners of an IVDU were begun on AZT between 1/87 - 3/88. RESULTS: 35 wer
- Treatment of symptomless HIV seropositive subjects by azidothymidine (AZT). a control study in 56 patients.
- Int Conf AIDS. 1989 Jun 4-9;5:413 (abstract no. W.B.P.368). Unique Identifier : AIDSLINE ICA5/00209489
- Vittecog D; Lefrere JJ; Lambin P; Mettetal JF; Rouzioux C; Courouce AM; Bach JF; Dpt of Immunology, Hopital Necker
- OBJECTIVE: To determine the effect of AZT in symptomless HIV seropositive subjects. METHODS: Comparison of 2 cohorts of 28 asymptomatic subjects (CDC II ou III) matched according to CD4 cell count (+/- 20/mm3) and p24 antigenemia (ag) (detectable or u
- An intermittent Zidovudine regimen: toxicity and efficacy.
- Int Conf AIDS. 1989 Jun 4-9;5:413 (abstract no. W.B.P.369). Unique Identifier : AIDSLINE ICA5/00209589
- Bodsworth N; Cooper DA; NHMRC Special Unit in AIDS Epidemiology and Clinical Research, U; NSW, Australia
- OBJECTIVE: To assess the efficacy of an intermittent regimen of Zidovudine. METHOD: 21 men (6 with AIDS, 15 with ARC) who developed hematotoxicity on continuous Zidovudine therapy despite dose reduction (1.2g----0.75g/day) were followed on an intermittent regimen of
- Long-term safety and efficacy of Zidovudine in large cohorts of IV drug abusers: 20 month experience with 200 asymptomatic, 500 ARC and 400 AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:413 (abstract no. W.B.P.370). Unique Identifier : AIDSLINE ICA5/00209689
- Vella S; Menniti IF; Agresti MG; National Institute of Health, Rome, Italy
- OBJECTIVE: To evaluate the long term safety and efficacy of Zidovudine (ZDV) when administered in I.V. drug abuser HIV-infected patients. METHODS: Data contained in the Italian National Registry of ZDV-treated patients have been analyzed. The Registry prospectively collected enrollment and quarterly follow-up forms of
- Use of Zidovudine (AZT) in injection drug use (IDU) related HIV infection - clinical outcome.
- Int Conf AIDS. 1989 Jun 4-9;5:413 (abstract no. W.B.P.371). Unique Identifier : AIDSLINE ICA5/00209789
- Cowan FM; Jones ME; Flegg PJ; MacCallum LR; Brettle RP; Gray JA; Infectious Diseases Unit, City Hospital, Edinburgh, UK
- OBJECTIVE: To evaluate clinical outcome of AZT therapy with IDU-related HIV infection (IDUHIV) in view of increased AZT levels in opiate users. METHOD: 322 HIV seropositives were assessed of which 253 (79%) were infected between 1983-85 by IDU. Of 51
- Zidovudine in ARC and AIDS patients: clinical, immunological and virological efficacy.
- Int Conf AIDS. 1989 Jun 4-9;5:413 (abstract no. W.B.P.372). Unique Identifier : AIDSLINE ICA5/00209889
- Hoffken G; Petri M; Deppermann KM; Ludwig WD; Mielke M; Zorr B; Medical Clinic Klinikum Steglitz
- OBJECTIVE: To evaluate the clinical, immunological and virological efficacy of Zidovudine ( AZT ) in ARC and AIDS patients (pts). METHODS: Open, non-comparative prospective trial. Evaluation criteria (3-months interval); (1) clinical: incidence of AIDS-
- Compliance with Zidovudine (AZT) therapy in an inner-city HIV-infected population.
- Int Conf AIDS. 1989 Jun 4-9;5:414 (abstract no. W.B.P.373). Unique Identifier : AIDSLINE ICA5/00209989
- Williams IY; Noel-Connor J; El-Sadr W; Harlem Hospital Center, New York, NY, USA
- Compliance to AZT was retrospectively evaluated in HIV-infected outpatients. Eighty-two patients (pts) were prescribed AZT between 11/86-7/88. Thirty-five are alive and on treatment (Rx), 7 were referred elsewhere, 1 requested stopping AZT and 11 neve
- Interferon (IFN) alpha+ AZT in AIDS-associated Kaposi's sarcoma (KS): final results of a phase I trial.
- Int Conf AIDS. 1989 Jun 4-9;5:414 (abstract no. W.B.P.374). Unique Identifier : AIDSLINE ICA5/00210089
- Krown S; Bundow D; Gansbacher B; Gold J; Flomenberg N; Armstrong D; Memorial Sloan-Kettering Cancer Center, New York, NY, USA
- OBJECTIVE: To evaluate the safety, tolerance and maximum tolerated dose (MTD) of IFN-alpha+ AZT in AIDS patients (pts) with KS; to assess antitumor, immunological and antiviral effects of the combination. METHODS: HIV-positive adults with biopsy-prove
- Outpatient transfusion therapy for retrovir-associated anemia.
- Int Conf AIDS. 1989 Jun 4-9;5:414 (abstract no. W.B.P.375). Unique Identifier : AIDSLINE ICA5/00210189
- Weiss S; Visser E; Rodgers P; McMeeking A; Schlamm H; AIDS Program, Bellevue Hospital Center, New York, NY, USA
- OBJECTIVE: To demonstrate the feasibility and safety of outpatient transfusion therapy for patients with Retrovir- associated anemia (RAA) METHODS: In a designated section of the general outpatient clinic of a large municipal hospital in New York, up to three patients with RAA, with a hematocrit between 18 and 30, wer
- Self care nursing for AIDS/ARC via computer networks.
- Int Conf AIDS. 1989 Jun 4-9;5:414 (abstract no. W.B.P.376). Unique Identifier : AIDSLINE ICA5/00210289
- Brennon PF; Ripich S; Frances Payne Bolton School of Nursing, Case Western Reserve; University
- This three year study evaluates the use of a free, public access computer network as a vehicle for the delivery of nursing services in the treatment of Acquired Immune Deficiency Syndrome (AIDS) and AIDS-Related Complex (ARC). We proposed to augment traditional methods of nursing care delivery with a new approach that
- Complementary therapies at casey house hospice: a model for traditional/alternative interaction.
- Int Conf AIDS. 1989 Jun 4-9;5:414 (abstract no. W.B.P.377). Unique Identifier : AIDSLINE ICA5/00210389
- Berinati WE; Chair, Complementary Therapies Committee, Casey House Hospice; Inc. Mt. Sinai Hospital, Toronto, Ontario, Canada
- The descriptors alternative and traditional regarding care of the HIV infected individual often suggests a dichotomy which can imply a rift between medical and non-medical orientation. Casey House Hospice made a firm commitment, from the outset, to utilization of alternative therapies in its hospital-affiliated progra
- Problems in an AIDS hospice setting.
- Int Conf AIDS. 1989 Jun 4-9;5:414 (abstract no. W.B.P.378). Unique Identifier : AIDSLINE ICA5/00210489
- Bloom JA; Flannery J; Casey House Hospice, Toronto, Ontario, Canada
- Casey House is a free standing hospice dedicated to people with AIDS. The Hospice has 13 beds (12 palliative, 1 respite care) and opened in March 1988. It was expected that the emphasis of medical/nursing care would be on symptom management (pain, nausea, skin problems and minor infections). Although the residents/leg
- Development of a day facility for people with AIDS/HIV infections.
- Int Conf AIDS. 1989 Jun 4-9;5:415 (abstract no. W.B.P.379). Unique Identifier : AIDSLINE ICA5/00210589
- Kelly A; St. Stephen's Hospital, London, England
- OBJECTIVE: The Kobler Centre, attached to St Stephen s Hospital, London, aims to provide day care for AIDS/HIV patients in order that the patients remain at home independently for longer than previously. METHOD: A description of the commissioning and activities of the Centre during its first year of operation. RESULT:
- [Functions of psychiatry in a day hospital for HIV+ patients]
- Int Conf AIDS. 1989 Jun 4-9;5:415 (abstract no. W.B.P.380). Unique Identifier : AIDSLINE ICA5/00210689
- Linard F; Silvestre D; INSERM U 158 - Hopital Claude Bernard - Paris
- Implantable infusion ports in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:415 (abstract no. W.B.P.381). Unique Identifier : AIDSLINE ICA5/00210789
- Johnston L; Lynch Y; Roy P; Depts. of Medicine, Nursing, and Surgery, Victoria General; Hospital, Halifax, N.S. Canada
- OBJECTIVE: To review our experience with the use of implantable infusion ports (PAC) in AIDS patients compared to their use in non-AIDS patients. METHODS: Retrospective chart review of 15 AIDS and 16 non-AIDS (NA) patients who had a PAC inserted by the same surgeon. RESULTS: Since 1987, 15 of our AIDS patients (all me
- Follow-up of infants born in HIV-infected mothers in Argentina.
- Int Conf AIDS. 1989 Jun 4-9;5:415 (abstract no. W.B.P.382). Unique Identifier : AIDSLINE ICA5/00210889
- Massa B; Gomez CM; Albani H; Raposo N; Sala A; Fernandez N; Balbaryski J; Boxaca M; Weissenbacher M; Pedro Elizalde Hospital Buenos Aires, Argentina
- OBJECTIVE: To determine the risk factor and the serological, immunological and clinical evolution of the newborns of HIV-positive women. METHODS: A group of 8 infants born to HIV-infected women were admitted to a Children s hospital in Buenos Aires City between December 1987 and March 1988. They were studied clinicall
- The impact of AIDS on families of haemophiliacs in Wales.
- Int Conf AIDS. 1989 Jun 4-9;5:415 (abstract no. W.B.P.383). Unique Identifier : AIDSLINE ICA5/00210989
- Beese J; University of Wales College of Medicine, Cardiff, South Wales, UK
- OBJECTIVE: To describe the impact of AIDS on the families of affected Welsh Haemophiliacs. Anyone involved with haemophiliacs has to be impressed by their courage in getting on with the business of living in spite of the debilitating nature of the disease. Now over fifty individuals living in Wales are facing a new ob
- Lymphocytes cytochemistry behavior in hemophilic patients with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:416 (abstract no. Th.B.P.1). Unique Identifier : AIDSLINE ICA5/00211089
- Gamba G; Testa S; Ponichio L; Invernizzi R; Fazio PD; Ippoliti GB; Dipartimento di Medicina Interna e Terapia Medica, Sez. di; Clinica Medica II. IRCCS Policlinico San Matteo. Universita di; Pavia, Italy
- The cytochemical and immunological characterization of lymphocytes of 31 hemophilic patients (6 of whom anti HIV positive without symptoms and signs of AIDS) chronically treated with commercial clotting factor concentrates were studied. In comparison to aged cross matched male controls, haemophiliacs presented signifi
- Antiphospholipid antibodies and HIV infection in hemophilia.
- Int Conf AIDS. 1989 Jun 4-9;5:416 (abstract no. Th.B.P.2). Unique Identifier : AIDSLINE ICA5/00211189
- Testa S; Ponchio L; Montoni N; Montecucco CM; Cascone G; Gamba G; Dipartimento di Medicina Interna e Terapia Medica, Sez. di; Clinica Medica II e Sez. di Patologia Medica. IRCCS Policlinico; San Matteo. Universita di Pavia, Italy
- OBJECTIVE: To study the presence of antiphospholipid antibodies: lupus like (LAC) and anticardiolipin (ACA) in Hemophilia. Patients: 30 pts. with Hemophilia A. 6 pts. with Hemophilia B; 9 pts. positive for anti-HIV antibodies, without symptoms and signs of AIDS. METHODS: LAC diagnosed by prolongation of Russell Viper
- Absence of HIV-2-infection in hemophilia in Buenos Aires.
- Int Conf AIDS. 1989 Jun 4-9;5:416 (abstract no. Th.B.P.3). Unique Identifier : AIDSLINE ICA5/00211289
- Bouzas MB; Simon F; Muchinik G; Picchio G; Brun Vezinet F; Mathov I; IIHEMA, Academia Nacional de Medicina, Buenos Aires, Argentina
- OBJECTIVE: Since HIV-2 probably spread via the same transmission routes as HIV-1, and considering that our patients received American and European concentrates, we evaluated HIV-2 antibodies in hemophiliacs previously screened for HIV-1. METHODS: Presence of HIV-2 antibodies was investigated in the sera of 60 hemophil
- HIV-infection and chagas' disease in hemophiliacs in Argentina.
- Int Conf AIDS. 1989 Jun 4-9;5:416 (abstract no. Th.B.P.4). Unique Identifier : AIDSLINE ICA5/00211389
- Bouzas MB; Corral R; Muchinik G; Grinstein S; Campestri R; Perez BR; IIHEMA, Academia Nacional de Medicina Buenos Aires, Argentina
- OBJECTIVE: To analyze the relation between HIV-infection and Chagas disease (CH) in 72 hemophiliacs (HF). METHODS: HIV serology was assayed thru ELISA (Abbott, recombinant). Positively reacting samples were confirmed thru Immunofluorescence or Western blot (Dupont). CH diagnosis was performed by means of direct agglu
- Response to hepatitis B immunization in hemophiliac children: relationship to human immunodeficiency type 1 (HIV-1) virus infection.
- Int Conf AIDS. 1989 Jun 4-9;5:416 (abstract no. Th.B.P.5). Unique Identifier : AIDSLINE ICA5/00211489
- Chan W; Petric M; Wang E; Koren G; Read S; Blanchette V; Departments of Pediatrics and Virology 1, Hospital for Sick; Children, Toronto, Ontario, Canada
- Hemophiliacs who receive pooled plasma concentrates for control of bleeding are at high risk for hepatitis B infection. In our Hemophilia Clinic, children susceptible to hepatitis B infection (-ve HBsAg;-ve anti-HBsAg) have been immunized using a plasma- derived hepatitis B vaccine (Heptavax-B Merck Sharp and Dohme).
- Beneficial effect of an ultrapure factor VIII concentrate on hypergammaglobulinemia in HIV-positive hemophiliacs.
- Int Conf AIDS. 1989 Jun 4-9;5:416 (abstract no. Th.B.P.6). Unique Identifier : AIDSLINE ICA5/00211589
- Schulman S; Johnsson H; Dept of Internal Medicine, Karolinska Hospital, Stockholm, Sweden
- OBJECTIVE: Elevated IgG-levels are often seen in hemophiliacs. The etiology is multifactorial, including passive transfer of IgG via the factor concentrate, allogenic stimulation by foreign proteins, chronic hepatitis and HIV-infection. Until recently the concentrates contained a multitude of plasma proteins and less
- Hemophilia, septic arthritis and human immunodeficiency virus.
- Int Conf AIDS. 1989 Jun 4-9;5:416 (abstract no. Th.B.P.7). Unique Identifier : AIDSLINE ICA5/00211689
- Jarzem P; Tsoukas C; Burke D; Strawczynski H; Growe G; Poon MC; Universities of McGill, British Columbia, Canada
- OBJECTIVES: Recent clinical observations have led us to believe that the incidence of septic arthritis (SA) in the hemophiliac population has risen sharply. To confirm this and determine the cause we examined the records of patients enrolled in the Canadian National Hemophiliac Study (CNHS). POPULATION STUDIES: 372 pa
- Longitudinal analyses of HIV-specific antibody responses in hemophiliacs with long-term HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:417 (abstract no. Th.B.P.8). Unique Identifier : AIDSLINE ICA5/00211789
- Flomenberg P; Honnen W; Revesz K; Chen HC; Choy A; Hilgartner M; Conway J; Pinter A; New York Veterans Administration Medical Center, New York, New; York, USA
- OBJECTIVES: To identify parameters of the serological response to HIV which may correlate with prognosis, using sequential bleeds from a 40 hemophiliacs, infected for an average of seven years. METHODS: Titers of antibodies against specific HIV antigens were determined by a sensitive radioimmunoprecipitation assay (RI
- [Prospective study of a group of 28 young hemophiliacs infected with the HIV virus]
- Int Conf AIDS. 1989 Jun 4-9;5:417 (abstract no. Th.B.P.9). Unique Identifier : AIDSLINE ICA5/00211889
- Tricoire J; Robert A; Puel J; Gayet C; Boneu B; Regnier C; Pediatrie B, CHU Purpan, 31059 Toulouse Cedex, France
- Immunological and virological findings in paradoxical HIV1 seronegative multi-transfused haemophiliacs (1983-1989).
- Int Conf AIDS. 1989 Jun 4-9;5:417 (abstract no. Th.B.P.10). Unique Identifier : AIDSLINE ICA5/00211989
- Berthier A; Chamaret S; Ameisen J; Laure F; Montagnier L; Centre Rey-Leroux 35 a Bouexiere Paris - France
- Absence of anti gag/anti env Ab. seroconversion in a number of multitransfused haemophiliacs (treated before 1985 with the same blood products as seropositive haemophiliacs), appears paradoxal. In this view an immunological and virological study was conducted in 30 seronegative haemophiliacs (replacement therapy befor
- [Evolution of human immunodeficiency virus infection in 69 seropositive hemophiliacs]
- Int Conf AIDS. 1989 Jun 4-9;5:417 (abstract no. Th.B.P.11). Unique Identifier : AIDSLINE ICA5/00212089
- Ferrer Le Coeur F; Meyohas MC; Hivert P; Eliaszewicz M; Lebas J; Frottier J; Centre National de Transfusion Sanguine (CNTS) Paris, France
- Progression of HIV-infection in 46 hemophilic patients.
- Int Conf AIDS. 1989 Jun 4-9;5:417 (abstract no. Th.B.P.12). Unique Identifier : AIDSLINE ICA5/00212189
- Brunkhorst U; Tschechne B; Barthels M; Schedel I; Deicher H; Hannover Medical School, Hannover, FRG
- OBJECTIVE: To study the incidence of AIDS in relation to progression parameters in hemophilic patients. METHODS: 47 patients (age 13-58) who seroconverted between 1982-84 were examined during 24 mo (1987/88). CDC stage and the following parameters were documented: p24 antigen, disappearance of p24 antibodies, CD4+ cel
- Clinical signs and death causes in HIV+ hemophiliacs (hem) with progressing disease.
- Int Conf AIDS. 1989 Jun 4-9;5:418 (abstract no. Th.B.P.13). Unique Identifier : AIDSLINE ICA5/00212289
- Perez BR; Anselmo A; de Tezanos Pinto M; Muchinik G; Bouzas MB; Rickard E; IIHEMA, Academia Nacional de Medicina, Buenos Aires, Argentina
- OBJECTIVE: To study clinical signs of hem with AIDS. METHODS: Up to January, 1989, 467 hem were studied: 407 Hemophilia A (HeA) (87.15%) and 60 Hemophilia B (HeB) (12.85%). HIV antibodies were detected in 158 hem (33.83%) thru EIA (Abbott) and confirmed thru IFA and ENVACOR (Abbott). RESULTS: Out of the 158 hem, 37 (2
- Hemophiliac population of Costa Rica from 1979 to 1989.
- Int Conf AIDS. 1989 Jun 4-9;5:418 (abstract no. Th.B.P.14). Unique Identifier : AIDSLINE ICA5/00212389
- Taylor L; Montero C; Cordero R; Astua MC; Roy A; Luftig R; Visonal KA; Louisiana State University-International Center for Medical; Research & Training, (LSU-ICMRT), San Jose, Costa Rica
- OBJECTIVE: To analyze the serological profile in the hemophiliac population in Costa Rica . METHODS: Serum samples stored in the LSU-ICMRT serum bank were tested with anti-HIV ELISA (Abbott HTLV-III), Western blot (LSU-ICMRT), HIV antigen (vironostika-Organon), IRMA HBsAg and ant
- An immunological follow-up in hemophilic non-converters after treatment with an HIV-contaminated batch.
- Int Conf AIDS. 1989 Jun 4-9;5:418 (abstract no. Th.B.P.15). Unique Identifier : AIDSLINE ICA5/00212489
- Schulman S; Berntorp E; Dept of Internal Medicine, Karolinska Hospital, Stockholm Sweden
- OBJECTIVE: In 1985 four Swedish hemophilia B-patients were infected by a batch of a F IX-concentrate, contaminated with HIV. Another 11 patients, the risk group, treated with the same batch, did not show seroconversion for anti-HIV. We have followed them carefully for signs of HIV-infection, and we have compared them
- Natural history of HIV infection in large hemophilia cohort: follow-up since 1983; 1988/89 update.
- Int Conf AIDS. 1989 Jun 4-9;5:418 (abstract no. Th.B.P.16). Unique Identifier : AIDSLINE ICA5/00212589
- Beth-Giraldo E; Miraglia E; De Biasi R; Rocino A; Martucci F; Giraldo G; Ist. Naz. Tumori Fond. Pascale and Center Med. Soc. Hemophilia,; Osp. N. Pellegrini, Naples, Italy
- OBJECTIVE: Multidisciplinary longterm follow-up studies on a large cohort of subjects (greater than 100 HIV+ of 280 patients) with coagulation defects to establish the effect and outcome of HIV infection and co-factors in hemophiliacs. METHODS: Immunologic and virologic profiles are evaluated twice yearly and correlat
- Natural history of HIV infection in a group of hemophiliacs with known year of seroconversion.
- Int Conf AIDS. 1989 Jun 4-9;5:418 (abstract no. Th.B.P.17). Unique Identifier : AIDSLINE ICA5/00212689
- Karafoulidou A; Gialeraki A; Hatzakis A; Economidou J; Psarra K; Markakis C; Makris P; Mandalaki T; Laikon Hosp., Athens, Greece
- OBJECTIVE: To determine the incidence of the serious clinical outcome of HIV infection and to assess various prognostic markers of progression. METHODS: Seroconversion to HIV was documented by ELISA and WB or RIP in 42 hemophiliacs. The seroconversions occurred between 1980-1985. RESULTS AND CONCLUSIONS: By November 1
- HIV-1 infection in children with hemophilia a and b.a report from the canadian pediatric hemophilia AIDS study group.
- Int Conf AIDS. 1989 Jun 4-9;5:418 (abstract no. Th.B.P.18). Unique Identifier : AIDSLINE ICA5/00212789
- Blanchette V; The Hospital for Sick Children, Division of Haemotology/Oncology,; Toronto, ON, Canada
- A survey of HIV-1 antibody+ ve pediatric hemophiliacs (age less than or equal to 18 years on 01/01/89) followed in comprehensive care hemophilia clinics in Canada , was conducted in January 1989. Seventeen Centres in 9 Provinces are represented in this report. The results of the sur
- Hemophiliac age affects immune functions in HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:419 (abstract no. Th.B.P.19). Unique Identifier : AIDSLINE ICA5/00212889
- Andes WA; Wulff K; Lemoine C; Daul C; Morgan J; DeShazo RD; The Louisiana Comprehensive Hemophilia Care Center, Louisiana USA
- We have followed approximately 200 hemophiliacs (H) at our State Center since 1980. Overall 55% (103) of the patients who used any non-treated factor VIII or IX concentrates seroconverted. Of those children (C less than 13) 29/99, adolescents (Ado less than 18) 22/45, and adults (Adu) 52/117 develop specific HIV antib
- A prospective study of HIV infection in children with hemophilia.
- Int Conf AIDS. 1989 Jun 4-9;5:419 (abstract no. Th.B.P.20). Unique Identifier : AIDSLINE ICA5/00212989
- Ali K; Tsoukas C; Card R; Garvey D; Growe G; Kobrinsky N; Poon MC; Rivard G; Ross E; Rubin S; et al; Univ. of Memorial, McGill, Saskatchewan, Toronto, Manitoba,; Calgary, Canada
- OBJECTIVES: A multicenter study was conducted in Canada between Jan.1,1985 and Jan.1 1989 to determine the prevalence of HIV infection among hemophiliacs and to monitor their clinical and immune status. METHODS: 98 children were initially enrolled and 89 are currently followed. Phy
- [Contamination of a young hemophiliac by the HIV2 virus]
- Int Conf AIDS. 1989 Jun 4-9;5:419 (abstract no. Th.B.P.21). Unique Identifier : AIDSLINE ICA5/00213089
- Tricoire J; Robert A; Puel J; Brun-Vezinet F; Gayet C; Regnier C; Pediatrie B, CHU Purpan, 31059 Toulouse Cedex, France
- Pre-existing cytomegalovirus infection increases the progression towards AIDS in a cohort of haemophiliacs.
- Int Conf AIDS. 1989 Jun 4-9;5:419 (abstract no. Th.B.P.22). Unique Identifier : AIDSLINE ICA5/00213189
- Webster A; Lee C; Grundy JE; Emery VC; Kernoff P; Griffiths PD; Depts. of Virology and Haemotology, England
- OBJECTIVE: Does CMV enhance HIV pathogenicity? METHODS: IgG antibodies against CMV and against HSV (as a control) were measured by radioimmunoassay. HIV antibody was measured by enzyme immunoassay (Wellcome). RESULTS: The presence of CMV but not HSV antibodies,
- High burden of Epstein-barr virus in HIV-infected hemophiliac patients.
- Int Conf AIDS. 1989 Jun 4-9;5:419 (abstract no. Th.B.P.23). Unique Identifier : AIDSLINE ICA5/00213289
- Sumaya C; Martinez R; Parmley R; Drake J; Ench Y; Univ. of Texas Health Science Center, San Antonio, Texas, USA
- OBJECTIVE: To determine if HIV-infected hemophiliac patients have an excessive burden of Epstein-barr virus (EBV) that potentially could produce subsequent deleterious complications. METHODS: The patient group consisted of 47 patients with hemophilia (predominantly type A) and an underlying HIV infection (31 asymptoma
- HTLV-I in hemophiliacs in Argentina.
- Int Conf AIDS. 1989 Jun 4-9;5:419 (abstract no. Th.B.P.24). Unique Identifier : AIDSLINE ICA5/00213389
- Bouzas MB; Mathov I; Muchinik G; Campestri R; Perez BR; Vercauteren G; IIHEMA, Academia Nacional de Medicina, Buenos Aires, Argentina
- OBJECTIVE: To study the seroprevalence of HTLV-I antibodies on hemophiliacs. METHODS: Sera previously drawn from 127 hemophiliacs for assessment of HIV-1 incidence (51 -40.2%- HIV-1-pos. and 76 -59.8%- HIV-1-neg.) were studied to determine the impact of HTLV-I. Sera were screened for HTLV-I antibodies by means of an E
- Significance of viral superinfections by HTLV-I, ebv and cmv for immunological disorder in HIV-infected hemophiliacs.
- Int Conf AIDS. 1989 Jun 4-9;5:420 (abstract no. Th.B.P.25). Unique Identifier : AIDSLINE ICA5/00213489
- Okubo S; Yasunaga K; Kansai Medical University, Osaka, Japan
- In order to clarify the influence of viral superinfections by HTLV-I, EBV and CMV for immunological disorder in HIV-infected persons, 55 hemophiliacs were examined. Twenty-two of 55 were seropositive for HIV. Two of 22 were AIDS and 20 were AC. RESULTS: 1. Altho
- Living with HIV: a weekend retreat for teenagers and young adults with hemophilia.
- Int Conf AIDS. 1989 Jun 4-9;5:420 (abstract no. Th.B.P.26). Unique Identifier : AIDSLINE ICA5/00213589
- Martin J; Lindner L; Neil J; Hemophilia Assessment Clinic, Vancouver, BC, Canada
- OBJECTIVES: A weekend retreat was planned to: (1) provide a non-medical setting for socialization among teenagers and young adults with hemophilia. (2) promote discussion about HIV and hemophilia issues, (3) provide accurate information about hemophilia and HIV, (4) discuss issues of sexuality and transmission of HIV,
- Responding to the palliative care needs of persons with hemophilia and AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:420 (abstract no. Th.B.P.27). Unique Identifier : AIDSLINE ICA5/00213689
- Nera NM; Shearer RJ; Federal Centre for AIDS, Health and Welfare Canada, Ottawa, ON,; Canada
- Recent surveys and national workshops among comprehensive care centre personnel have indicated the growing concern to give attention to the palliative care needs of persons with hemophilia. Two surveys conducted in 1988 have shown that 950 of Canada s 2,300 classic hemophilia population have been infected with HIV. 84
- Psychosocial management of HIV infection among hemophiliacs in western Canada.
- Int Conf AIDS. 1989 Jun 4-9;5:420 (abstract no. Th.B.P.28). Unique Identifier : AIDSLINE ICA5/00213789
- McClure W; Lindner L; McDonald J; Bell C; Schwetz N; Akabutu J; Northern Alberta Comprehensive Hemophilia Centre, Edmonton,; Alberta, Canada
- OBJECTIVE: To evaluate the current psychosocial management of HIV infection among hemophiliacs at the five Western Canadian Comprehensive Hemophilia Centres. METHOD: All centres submitted a written report on their current approaches to the psychosocial management of HIV infection in hemophiliacs. The reports covered t
- AIDS and hemophilia: creating unique family dynamics.
- Int Conf AIDS. 1989 Jun 4-9;5:420 (abstract no. Th.B.P.29). Unique Identifier : AIDSLINE ICA5/00213889
- Roy MS; Charles M; Montreal Children's Hospital, Social Service Department,; Montreal, Quebec, Canada
- Hemophilia is a hereditary blood clotting disorder usually passed on from mother to son. The genetic aspect of hemophilia creates family dynamics unique within the AIDS community. HIV was acquired: 1) as a result of medical treatment for hemophilia. Families where HIV and hemophilia are present are faced with the dile
- Condom usage reported by female sexual partners of asymptomatic HIV seropositive hemophilic men.
- Int Conf AIDS. 1989 Jun 4-9;5:420 (abstract no. Th.B.P.30). Unique Identifier : AIDSLINE ICA5/00213989
- Price W; Merigan T; Peterman T; Research Triangle Institute, Research Triangle Park, NC, USA
- OBJECTIVE: To report condom usage rates among a sample of female sexual partners of HIV seropositive hemophilic males. METHOD: ACTG 036 is a placebo-controlled clinical trial of Zidovudine (ZDV) in HIV seropositive hemophilic men. Female sexual partners of these men are being enrolled in a prospective study of the eff
- Psychosocial and neuropsychological status of haemophiliacs and gay men with HIV infection: a controlled investigation.
- Int Conf AIDS. 1989 Jun 4-9;5:421 (abstract no. Th.B.P.31). Unique Identifier : AIDSLINE ICA5/00214089
- Catalan J; Klimes I; Bond A; Garrod A; Day A; Rizza C; Dept. Clinical Psychology and Oxford University Dept. Psychiatry; Warneford Hospital, Oxford, UK
- OBJECTIVE: To establish prevalence of psychosocial and neuropsychological problems in HIV+ subjects; to compare the two transmission groups; to identify the characteristics of those with problems. METHODS: HIV+ haemophiliacs (n=36) and HIV- haemophiliac controls (n=36) and HIV+ gays (n=20) and HIV- gay controls (n=25)
- Risk factors for psychiatric distress among hemophiliacs infected with HIV1.
- Int Conf AIDS. 1989 Jun 4-9;5:421 (abstract no. Th.B.P.32). Unique Identifier : AIDSLINE ICA5/00214189
- Dew MA; Ragni M; Nimorwicz P; University of Pittsburgh, Pittsburgh, PA, USA
- OBJECTIVES: To examine psychiatric correlates of HIV1 infection in a major risk group for AIDS; to identify psychosocial characteristics of HIV1+ men that increase their risk for psychiatric distress following infection. METHODS: All moderate/severe hemophiliacs residing in western Pennsylvania, USA, plus mild hemophi
- Prediction of safer sex practice and psychosocial distress in adults with hemophilia at risk for AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:421 (abstract no. Th.B.P.33). Unique Identifier : AIDSLINE ICA5/00214289
- Parish KL; Mandel J; Thomas J; Gomperts E; Childrens Hospital of Los Angeles, CA, USA
- OBJECTIVE: To determine which behavioral factors are predictive of consistent condom use and psychosocial distress in hemophilic adults at risk for AIDS. METHODS: A self-administered questionnaire was sent to all 975 identified persons with hemophilia in California in 1987-88. Items were designed to identify factors a
- Guidelines for dealing with pregnancy in seropositive hemophiliacs and their spouses.
- Int Conf AIDS. 1989 Jun 4-9;5:421 (abstract no. Th.B.P.34). Unique Identifier : AIDSLINE ICA5/00214389
- Kraus E; Forsberg A; Brettler D; New England Hemophilia Center, Worcester Memorial Hospital,; Worcester, Massachusetts, USA
- OBJECTIVE: To describe a protocol for HIV testing in pregnancies of seropositive hemophiliacs and their spouses. METHODS: All patients followed at the New England Hemophilia Center receive counselling concerning HIV transmission. Safe sex practices and avoidance of pregnancy is strongly advocated. However, pregnancies
- A team response to HIV/AIDS care in persons with hemophilia.
- Int Conf AIDS. 1989 Jun 4-9;5:421 (abstract no. Th.B.P.35). Unique Identifier : AIDSLINE ICA5/00214489
- Nera N; O'Niell R; Social Services Advisor, Federal Center for AIDS, Health and; Welfare Canada, Ottawa, Canada
- This presentation will describe how interdisciplinary dialogue days was used as an approach to team building in introducing HIV/AIDS care in Canadian Hemophilia Care Centers. Dialogue days conducted in 1987 and 1988 involved hematologists, nurses, coordinators, social workers and psychologists. The different health ca
- Tuberculosis in AIDS patients in Rio Grande do Sul: a new epidemic?
- Int Conf AIDS. 1989 Jun 4-9;5:421 (abstract no. Th.B.P.36). Unique Identifier : AIDSLINE ICA5/00214589
- Sprinz E; Kronfeld M; Hospital de Clinicas de Porto Alegre, Rio Grande do Sul, Brazil
- OBJECTIVE: Establish the incidence and the most common sites affected by Mycobacterium tuberculosis in AIDS patients in Rio Grande do Sul (RS) state. METHODS: It was reviewed, at random, 50 AIDS inpatients at Hospital de Clinicas de Porto Alegre between July and December 1988. It was considered positive if the culture
- Thoracic radiographic aspects of tuberculosis in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:422 (abstract no. Th.B.P.38). Unique Identifier : AIDSLINE ICA5/00214689
- Yamashita HK; Accetturi CA; Ribeiro SA; Stavale JN; Kambara AM; Department of Imaging Diagnostic
- The authors present an evaluation of thoracic X-rays in patients with AIDS and tuberculosis, its value for the diagnostic and therapeutic orientation. Patients were clinically classified according to CDC (Centers of Disease Control), of USA, being 25 men and 2 women, aged between 18 and 66 year, 16 homosexuals, 5 bise
- Gastrointestinal tuberculosis in AIDS patients: the Rio Grande do Sul experience.
- Int Conf AIDS. 1989 Jun 4-9;5:422 (abstract no. Th.B.P.39). Unique Identifier : AIDSLINE ICA5/00214789
- Sprinz E; Kronfeld M; Hospital de Clinicas de Porto Alegre, Rio Grande do Sul, Brasil
- OBJECTIVE: Study the incidence of gastrointestinal tuberculosis and its relation with diarrhea in Rio Grande do Sul (RS) state. METHODS: The registers of 50 AIDS inpatients at HCPA between July and December 1988 were reviewed (8 were excluded, as they did not have diarrhea. RESULTS: From the remaining 42 cases, in 9(2
- Tuberculosis and AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:422 (abstract no. Th.B.P.40). Unique Identifier : AIDSLINE ICA5/00214889
- Biancalana ML; Mendes WS; Rodrigues GA; Stefani HN; Le vi GC; Mendonca JS; Department of Infectious Diseases - Hospital do Servidor Publico; Estadual - Sao Paulo - Brazil
- Between 1985 and 1988 we studied 19 patients with positive anti-HIV serologic test and tuberculosis diagnosticated by positive culture for M. tuberculosis. Tuberculosis was the first manifestation of HIV related infections in 12 patients; concomitant with other HIV related conditions in four cases (two Kaposi sarcoma)
- Drug-resistant tuberculosis in AIDS and ARC.
- Int Conf AIDS. 1989 Jun 4-9;5:422 (abstract no. Th.B.P.41). Unique Identifier : AIDSLINE ICA5/00214989
- pablos-Mendez A; Raviglione MC; Battan RC; Department of Medicine, Cabrini Medical Center, NYC, NY, USA
- OBJECTIVE: Tuberculosis (TB) is now frequently reported in AIDS, and its proper treatment remains to be determined. We reviewed the prevalence of drug-resistant Mycobacterium tuberculosis in patients with AIDS or ARC. METHODS: We searched our mycobacteriology registry for all cases of TB from 1982 to 1988. Of 137 pati
- Mycobacterium kansasii (MK) infection in HIV infected patients: a 5 year review.
- Int Conf AIDS. 1989 Jun 4-9;5:422 (abstract no. Th.B.P.42). Unique Identifier : AIDSLINE ICA5/00215089
- Cardona L; Valainis G; Greer D; Tulane University Medical Center, LA, USA
- OBJECTIVE: A significant increase in the number of isolates of (MK) associated with HIV infected patients has been observed. We reviewed all patients (PTS) with + MK cultures identified at our mycobacteriology reference laboratory. METHODS: A retrospective review of all PTS with a+ culture between 1983-88 was performe
- Tuberculosis in HIV patients: correlation between natural history, clinical presentation and immunological status.
- Int Conf AIDS. 1989 Jun 4-9;5:423 (abstract no. Th.B.P.43). Unique Identifier : AIDSLINE ICA5/00215189
- Gerard; De Wit S; Sommereijns B; Clumeck N; Division of Infectious Diseases, St Pierre University Hospital,; Brussels, Belgium
- Tuberculosis (TB) associated with HIV infection is classified as TB of lungs and/or lymph nodes (LTB - CDC group IV C2) or disseminated TB (DTB - CDC group IV C1; AIDS). In order to assess the clinical and immunological relevance of considering both entities separately we studied 31 cases of TB (20 DTB, 11 LTB) diagno
- Surveillance for HIV/AIDS-related tuberculosis (TB) in the United States (US).
- Int Conf AIDS. 1989 Jun 4-9;5:423 (abstract no. Th.B.P.44). Unique Identifier : AIDSLINE ICA5/00215289
- Ciesielski C; Buehler J; Bloch A; Berkelman R; Centers for Disease Control, Atlanta, GA, USA
- OBJECTIVES: To assess the magnitude and distribution of HIV/AIDS-related TB morbidity and mortality in the U.S. METHODS: To describe TB and AIDS morbidity, State and local health departments match TB cases to AIDS cases diagnosed within the preceding 3 years. To describe TB and HIV/AIDS mortality, we used national vit
- Incidence, diagnosis and treatment of mycobacteriosis in AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:423 (abstract no. Th.B.P.45). Unique Identifier : AIDSLINE ICA5/00215389
- Heise W; Skorde J; Nehm K; Arasteh K; Habermann R; L'age M; Auguste-Viktoria-Hospital, Berlin, West Germany
- OBJECTIVE: To describe the main microbiological and clinical aspects and the incidence of mycobacteriosis in 33o HIV patients. METHODS: Different specimen (blood, urine, bronchoalveolar lavage, sputum, bone marrow, spinal fluid, stool, biopsies) were examined for mycobacteria microscopically and culturally. Clinical s
- Evidence of another epidemic: Tuberculosis and HIV in a NYC community hospital.
- Int Conf AIDS. 1989 Jun 4-9;5:423 (abstract no. Th.B.P.46). Unique Identifier : AIDSLINE ICA5/00215489
- Ciacco M; SpicehandlerD; St. Clare's Hospital and Health Center, New York, NY, USA
- OBJECTIVE: To analyze the recent rise of Mycobacterium tuberculosis (MTB) infection and disease in a NYC community hospital. METHODS: Review of MTB data from epidemiology files of 1984 - 1988. Retrospective analysis of data from patient and personnel health medical records. RESULTS: This 250 bed hospital, with a 75 be
- Influence of geographic distribution on a typical mycobacteriosis and isospora belli in Rio Grande do sul (Brazil).
- Int Conf AIDS. 1989 Jun 4-9;5:423 (abstract no. Th.B.P.47). Unique Identifier : AIDSLINE ICA5/00215589
- Kronfeld M; Sprinz E; Universidade Federal do Rio Grande do Sul
- OBJECTIVE: Show that in Rio Grande do Sul(RS) state atypical mycobacteriosis and Isospora belli are not frequent. METHODS: We reviewed 140 registers of AIDS inpatients at HCPA between June 1986 and November 1988 for the occurrence of atypical mycobacteriosis or Isospora belli infections. RESULTS: A possible case of My
- Factors influencing mortality in disseminated m. avium (MAI) infection in acquired immunodeficiency syndrome (AIDS).
- Int Conf AIDS. 1989 Jun 4-9;5:423 (abstract no. Th.B.P.48). Unique Identifier : AIDSLINE ICA5/00215689
- Sathe S; Kaminski Z; Kapila R; Kloser P; Reichman L; UMDNJ-New Jersey Medical School, Newark, New Jersey, USA
- Disseminated MAI in patients with AIDS is a common opportunistic infection (OI) and is unresponsive to therapy; yet its effect on the duration of survival is controversial. 54 patients with AIDS and MAI (Group I) and 23 patients without mycobacterial disease (Group II) were studied. The two groups were similar in demo
- Mycobacterium kansasii infection in 15 patients with class IV HIV infection: clinical and mycobacteriologic features.
- Int Conf AIDS. 1989 Jun 4-9;5:424 (abstract no. Th.B.P.49). Unique Identifier : AIDSLINE ICA5/00215789
- Blair S; Muller K; Kocka F; Muthusamy P; Renslow S; Department of Medicine; Department of Laboratories, Cook County; Hospital, Chicago, USA
- OBJECTIVE: To evaluate the clinical and mycobacteriologic features of M. kansasii infection in the presence of Class IV HIV infection. METHODS: All patients with M. Kansasii infection between 10/83 and 11/88 were cross-referenced with all persons with Class IV HIV infection, and a retrospective chart review was conduc
- Seroprevalence of HIV infection in 183 consecutive patients with tuberculosis (TB) at a New York city hospital.
- Int Conf AIDS. 1989 Jun 4-9;5:421 (abstract no. Th.B.P.50). Unique Identifier : AIDSLINE ICA5/00215889
- Shafer RW; Chirgwin KD; Glatt AE; Dahdouh MA; Landesman SH; SUNY-Health Science Center at Brooklyn, NY, USA
- OBJECTIVES: 1)Determine the prevalence of HIV infection in pts with TB. 2)Determine the extent of immunosuppression in HIV infected pts with TB. METHODS: Between 10/87-6/88, all hospitalized adults with newly diagnosed, culture-proven TB, were offered HIV testing and T4 lymphocyte levels. RESULTS: 70(38%) were intrave
- Tuberculosis as pulmonary complication AIDS - associated.
- Int Conf AIDS. 1989 Jun 4-9;5:424 (abstract no. Th.B.P.51). Unique Identifier : AIDSLINE ICA5/00215989
- Piersantelli N; Guida B; Dpt.Inf.Dis.Galliera Hosp.Genoa, Italy
- OBJECTIVE: To study pulmonary Mycobacterium tuberculosis (Mt) infection in AIDS patients (pts). METHODS: In 42 cases of AIDS from June 86 to June 88 we observed 10 male pts affected by pulmonary tuberculosis: they were heroin-addicts aging from 28 to 40. RESULTS: Bacteriological tests were positive for Mt in sputum (3
- Tuberculosis in HIV-infected individuals in the province of British Columbia (1983-1988).
- Int Conf AIDS. 1989 Jun 4-9;5:424 (abstract no. Th.B.P.52). Unique Identifier : AIDSLINE ICA5/00216089
- Blackie S; Vedal S; Lawson LM; Rudey J; Montaner JS; AIDS Research Programme, St. Paul's Hospital Vancouver, BC,; Canada
- OBJECTIVE: To describe the clinical presentation, laboratory findings and outcomes of all cases of tuberculosis (TB) in HIV infected individuals diagnosed in the province of British Columbia over the 6 year period ending December 31, 1988. METHODS: Cases of TB in HIV infected individuals were identified by a linkage b
- Fever, weight loss, anemia, splenomegaly and abdominal lymphadenopathy are highly predictive of disseminated mycobacteriosis in patients who are HIV antibody positive.
- Int Conf AIDS. 1989 Jun 4-9;5:424 (abstract no. Th.B.P.53). Unique Identifier : AIDSLINE ICA5/00216189
- Cone L; Woodard D; Wade D; Curry N; Boughton W; Fiala M; Section of Infectious Diseases, Department of Medicine,; Departments of Radiology and Pathology, Eisenhower Medical; Center, Rancho Mirage, CA, USA
- Disseminated mycobacteriosis due to M. avium-intracellulare (MAI) or less commonly due to M. tuberculosis (MTB) occurs in nearly 25% of patients with AIDS during the course of their illness. In most individuals the lungs are spared and organisms are found in lymph nodes, blood bone marrow, liver, spleen and gastrointe
- Mycobacteriosis and AIDS therapeutic approaches.
- Int Conf AIDS. 1989 Jun 4-9;5:424 (abstract no. Th.B.P.54). Unique Identifier : AIDSLINE ICA5/00216289
- Schurmann D; Ruf B; Mauch H; Pohle HD; Department of Internal Medicine, Rudolf Virchow University; Hospital, Freie Universitat Berlin
- OBJECTIVE: To gain data on the effectiveness of chemotherapy in mycobacteriosis. METHODS: Course and the effect of therapy was evaluated in 51 patients. Drug susceptibility of strains involved was determined. RESULTS: Tuberculosis (TB): 17/21 patients were treated (common drugs for 9 months, followed by maintenance th
- Detection of antimycobacterial antibodies in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:425 (abstract no. Th.B.P.55). Unique Identifier : AIDSLINE ICA5/00216389
- Farber C; De Bruyn J; Yernault JC; Van Vooren JP; Department of Immunology and Department of Pneumology, Hospital; Erasme, Universitc Libre de Bruxelles, Bruxelles, Belgium
- OBJECTIVE: To facilitate the diagnosis of mycobacterial diseases in HIV infected patients. METHODS: A serological assay detecting IgG directed against mycobacterial culture filtrate in HIV positive and AIDS patients with negative (ID -) and positive (ID+) PPD skin tests. TABULAR DATA, SEE ABSTRACT VOLUME. RESULTS: CON
- Clinical immunological and prognostic aspects of tuberculosis (TB) in HIV patients.
- Int Conf AIDS. 1989 Jun 4-9;5:425 (abstract no. Th.B.P.56). Unique Identifier : AIDSLINE ICA5/00216489
- Narciso P; Leoni GC; Sette P; Spinazzola F; Tozzi V; Giuseppe V; U.S.L. RM/10 L. Spallanzani Hospital Dept. Infections Diseases,; Rome, Italy
- OBJECTIVE: To correlate clinical aspects of TB with immunological data. To determine if any among chest X ray (XR) patterns of pulmonary involvement could be a predictor of evolution to overt AIDS. METHODS: 35 HIV Ab +ve patients with pulmonary and extrapulmonary TB observed since March 1986 to Dec 1988 were evaluated
- [Tuberculosis and AIDS in Spain]
- Int Conf AIDS. 1989 Jun 4-9;5:425 (abstract no. Th.B.P.57). Unique Identifier : AIDSLINE ICA5/00216589
- Dcana I; De Luis A; Ruiz I; Marti N; Vida R; Martinez-Vazquez JM; Departements de Medecine Interne, Microbiologie et pneumologie; Hospital Valle de Hebron. Universite autonomique de Barcelone.; Barcelone. Espagne
- Generalized infection with an unidentified acid-fast microorganism (AFB).
- Int Conf AIDS. 1989 Jun 4-9;5:425 (abstract no. Th.B.P.58). Unique Identifier : AIDSLINE ICA5/00216689
- Mach N; Chang HR; Piguet JD; Portaels F; Auckenthaler R; Hirschel B; Divisions of Pathology, Microbiology, Infectious Diseases, and; the Clinique Medicale, Hopital Cantonal Universitaire, Geneva,; Switzerland
- CASE REPORT: A HIV-seropositive former i.v. drug user presented with enlargement of liver and spleen; he died 20 months later after a 30kg weight loss, diarrhea, and ascites. RESULTS: During life, biopsies of liver and duodenum, ascites, buffy coat, urine and feces all revealed massive amounts of AFB; AFB infiltrated
- Tuberculosis and AIDS in Frankfurt.
- Int Conf AIDS. 1989 Jun 4-9;5:425 (abstract no. Th.B.P.59). Unique Identifier : AIDSLINE ICA5/00216789
- Muller; Koller-Lampert L; Jakschik A; Brodt R; Schulze-Werninghaus G; Helm EB; Universitatsklinik Frankfurt, Zentrum fluur Innere Medizin,; Infektiologie, Th.-Stern-Kai 7, 6000 Frankfurt/M, FRG
- OBJECTIVE: To describe frequency, clinical picture, course and significance of tuberculosis (TB) with AIDS in Frankfurt. METHOD: Since 1984, all TB cases with HIV infection have been examined prospectively. All patients (pts) get quadruple standard therapy and are clinically followed up regularly even after completion
- Mnt infection in 63 of 328 AIDS patients in Frankfurt.
- Int Conf AIDS. 1989 Jun 4-9;5:425 (abstract no. Th.B.P.60). Unique Identifier : AIDSLINE ICA5/00216889
- Koller-Lampert L; Brodt R; Jakschik A; Staszewski S; Helm EB; Universitatsklinik Frankfurt, Zentrum der Inneren Medizin,; Infektiologie, Th-Stern-Kai 7, 6000 Frankfurt/M, FRG
- OBJECTIVE: To investigate occurrence and significance of evidence of different mycobacteria in HIV-infected (HIV+) patients (pts) in the course of disease. METHODS: All our HIV + pts staged WR 4-6 are regularly tested for colonization and/or infection with MNT (stool, urine, sputum); all pts with microscopic or cultur
- Aminoglycoside antibiotics have potential value in the treatment of mycobacterium avium complex (MAC) disease in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:426 (abstract no. Th.B.P.61). Unique Identifier : AIDSLINE ICA5/00216989
- Pattisapu RR; Gangaddharam; Kesavalu L; Perumal VK; Parikh K; Ghori N; National Jewish Center for Immunology and Respiratory Medicine,; Denver, Colorado, USA
- Mycobacterium avium complex (MAC) cause serious opportunistic infections in AIDS patients. We established that the beige (C57B1/6/bg/bg) mice are most susceptible to experimental MAC infections. In other studies we showed that in many immunobiological respects, beige mice are similar to AIDS patients. Using the beige
- Plasmids influence virulence of mycobacterium avium complex (MAC) strains in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:426 (abstract no. Th.B.P.62). Unique Identifier : AIDSLINE ICA5/00217089
- Gangadharam PR; Perumal VK; Crawford JH; Bates JH; National Jewish Center for Immunology and Respiratory Medicine,; Denver, Colorado
- Mycobacterium avium complex (MAC) organisms are important opportunistic infections encountered in AIDS patients. More than 50% of AIDS patients are known to have MAC infections and most of them succumb to the disease within one year of diagnosis. Among several differences observed between MAC strains from AIDS and non
- Incidence of acquired immunodeficiency syndrome (AIDS) in outpatients with tuberculosis.
- Int Conf AIDS. 1989 Jun 4-9;5:426 (abstract no. Th.B.P.63). Unique Identifier : AIDSLINE ICA5/00217189
- Ribeiro SA; Togeiro SM; Acceturi CA; Yamashita HK; Escola Paulista de Medicina, S. Paulo, SP, Brazil
- This study was performed in a Health Center from Jan 1, 1987 to Dec 31, 1988; and 15 of 453 (3,3 percent) patients of tuberculosis had AIDS. In Brazil , the association of both AIDS and tuberculosis had been related as 22% of outpatients and 50% of inpatients. Of 15 cases of tubercu
- [Tuberculosis (TB) and AIDS; case reports observed in parisian hospitals; epidemiological implications]
- Int Conf AIDS. 1989 Jun 4-9;5:426 (abstract no. Th.B.P.64). Unique Identifier : AIDSLINE ICA5/00217289
- Chretien J; Papillon F; Universite PARIS V, Hopital Laennec. Paris, France
- Tuberculosis in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:426 (abstract no. Th.B.P.65). Unique Identifier : AIDSLINE ICA5/00217389
- Iribarren JA; Arrizabalaga J; Garde C; Munoz-Baroja I; Perez-Trallero E; Zulaica D; Hospital Na Sa de Aranzazu.San Sebastian.Spain
- OBJECTIVES: Evaluation of: a) the prevalence of extrapulmonary tuberculosis in AIDS patients, b) clinical forms of presentation of this disease, c) eventual development of opportunistic infections (OI), d) response to treatment and adverse therapeutic reactions. METHODS: A prospective study was made of 112 patients di
- Association between tuberculosis and AIDS in Rio de Janeiro - Brazil.
- Int Conf AIDS. 1989 Jun 4-9;5:426 (abstract no. Th.B.P.66). Unique Identifier : AIDSLINE ICA5/00217489
- Morais de Sa CA; Eyer-Silva W; Severo R; Guimaraes-Dias M; Oliveria DP; Sion FS; Gaffree & Guinle University Hospital
- OBJECTIVE: To study the incidence and characteristics of TB among AIDS patients. METHODS: We retrospectively reviewed the medical records of 235 patients who met the current CDC surveillance case definition of AIDS. We look for clinical, pathological, radiological and microbiological evidence of TB and also compared e
- The clinical impact of mycobacterial infections in HIV infected persons.
- Int Conf AIDS. 1989 Jun 4-9;5:427 (abstract no. Th.B.P.67). Unique Identifier : AIDSLINE ICA5/00217589
- Boldt K; Chomyc S; Miedzinski L; Taylor G; Evans GA; University of Alberta, Edmonton, Alberta, Canada
- OBJECTIVE: To assess the impact of mycobacterial infections in AIDS and HIV infected patients in the Province of Alberta (to date 125 AIDS, 706 known seropositives). METHODS: Mycobacterially infected patients were identified by reviewing laboratory isolates from the Provincial Tuberculosis Laboratory for the period 19
- Poor compliance is the major obstacle in controlling the HIV-associated tuberculosis (TB) outbreak.
- Int Conf AIDS. 1989 Jun 4-9;5:427 (abstract no. Th.B.P.68). Unique Identifier : AIDSLINE ICA5/00217689
- Brudney K; Dobkin J; Dept. of Medicine, Harlem Hospital, New York, NY, USA
- Increasing TB in New York City is often linked to the HIV epidemic. However poor compliance(C) is a key factor leading to frequent readmission and probably many secondary cases. The impoverished population at risk for both HIV and TB has features strongly linked to low C: intravenous drug abuse (IVD), unemployment, ho
- Successful antituberculous treatment with various drug regimens in patients with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:427 (abstract no. Th.B.P.69). Unique Identifier : AIDSLINE ICA5/00217789
- Carton J; Carcaba V; Maradona JA; Moris J; Ferro J; Colmeiro A; Hospital Universitario. Oviedo. Spain
- OBJECTIVE: To asses short-term efficacy and toxicity for several antituberculous drug regimens in patients with HIV infection and tuberculosis (TB). METHODS: 53 patients with HIV infection and TB (72% culture and sensitivity proved) received antituberculous therapy; drugs used and daily dosages were: Rifarpin (RMP), 6
- Natural history of m. leprae and HIV co-infection.
- Int Conf AIDS. 1989 Jun 4-9;5:427 (abstract no. Th.B.P.70). Unique Identifier : AIDSLINE ICA5/00217889
- Pean C; Pape JW; Deschamps MM; Dambreville M; Johnson WD; Inst. Cardinal Leger contre la lepre, P-au-P. Haiti
- OBJECTIVE: To determine the natural history of leprosy in HIV-infected patients. METHODS: We studied 275 leprosy patients between 1985 and 1988. HIV testing on all patients utilized an ELISA with RIA confirmation. The diagnosis and treatment of leprosy were according to WHO criteria and protocols. Patients were follow
- Mycobacterium avium-intracellulare infection limited to the skin and lymph nodes in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:427 (abstract no. Th.B.P.71). Unique Identifier : AIDSLINE ICA5/00217989
- Barbaro D; Orcutt VL; Coldiron BM; Dept. Internal Medicine, University of Texas Southwestern Medical; School, USA
- Three patients with the acquired immunodeficiency syndrome (AIDS) developed cutaneous abscesses from which Mycobacterium-avium intracellulare (MAI) was isolated. All three patients had begun therapy with Zidovudine ( AZT ) within three months prior to t
- Mycobacterial infection in AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:427 (abstract no. Th.B.P.72). Unique Identifier : AIDSLINE ICA5/00218089
- Damiano F; Fantoni M; Ventura G; Antinori A; Ardito F; Archibusacci C; Clinica Malattie Infecttive, Microbiologia-Universita; Cattolica-Roma-Italy
- OBJECTIVE: To evaluate the frequency of mycobacterial infection in AIDS pts. METHODS: 33 consecutively followed pts were examinated for the presence of mycobacteria in clinical specimens (blood, bone marrow, sputum, Bal, urine, stool, spinal fluid, biopsies) using standard techniques. RESULTS: Four pts (12,1%) had dis
- Epidemiological and environmental features of mycobacteria other than tuberculosis in Germany.
- Int Conf AIDS. 1989 Jun 4-9;5:428 (abstract no. Th.B.P.73). Unique Identifier : AIDSLINE ICA5/00218189
- Peters M; Ruf B; Schurmann D; Schroder KH; Mauch H; Pohle HD; Department of Internal Medicine, Rudolf Virchow University; Hospital FRG
- Mycobacteria other than tuberculosis (MOTT) are common pathogens in AIDS patients. Mycobacterium avium-intracellulare (MAI) are the most important atypical mycobacteria species. To evaluate whether infections and colonization with MOTT are common only in HIV infected patients, the frequency of MOTT in immunosuppressed
- Tuberculosis and AIDS-Rio de Janeiro, Brazil: 1983-1988.
- Int Conf AIDS. 1989 Jun 4-9;5:428 (abstract no. Th.B.P.74). Unique Identifier : AIDSLINE ICA5/00218289
- Kritski AL; Matida A; Galvao-Castro B; Institute of Physiology and Pneumology, Federal University of Rio; de Janeiro (RJ)
- OBJECTIVE: To describe clinical aspects of patients with AIDS and tuberculosis (AIDS/TB) and compare to AIDS patients without TB (AIDS/NON TB). METHODS: 718 persons meeting the CDC(1987) or Brazilian Ministry of Health (1987) criteria of AIDS reported from State of Rio de Janeiro, in the period 1983-1988 (24th week en
- HIV infection alters immune response to cigarette smoking.
- Int Conf AIDS. 1989 Jun 4-9;5:428 (abstract no. Th.B.P.75). Unique Identifier : AIDSLINE ICA5/00218389
- Royce R; Winkelstein W; University of California at Berkeley, Berkeley, California, USA
- OBJECTIVE: To investigate immune response to smoking and HIV infection. METHODS: CD4 and CD8 T-Cell counts (cells/ul), smoking status and smoking dose (packs/day) were evaluated twice yearly for 3.5 years in the San Francisco Men s Health Study cohort, a probability sample formed in 1984. RESULTS: In 586 men not infec
- Non specific pneumonitis (NSP) in HIV seropositive adults.
- Int Conf AIDS. 1989 Jun 4-9;5:428 (abstract no. Th.B.P.76). Unique Identifier : AIDSLINE ICA5/00218489
- Gritti FM; Poletti V; Spiga L; Sabbatani S; Grillo A; Infect. Dis. Dep., Ospedale Maggiore and Pneumology Dep.,; Ospedale Bellaria, Bologna, Italy
- OBJECTIVE: To determine incidence of NSP, which occurs in some HIV seropositive adults, and to compare usefulness of different procedures for its diagnosis. METHOD: This is a retrospective study of 11 NSP diagnosed by transbronchial biopsy (TBB) on 63 HIV positive patients (pts) with respiratory symptoms. All underwen
- Expression of cell surface activation antigens in bronchoalveolar lavage (BAL) T-Cells from HIV-infected patients undergoing pneumonitis.
- Int Conf AIDS. 1989 Jun 4-9;5:428 (abstract no. Th.B.P.77). Unique Identifier : AIDSLINE ICA5/00218589
- Aspa J; Jimenez ML; Gonzalez A; Santos I; Madrid FS; Lopez-Botet M; Department of Pneumology, Microbiology, Internal Medicine,; Immunology, Hospital de la Princesa, Madrid. Spain
- In the present study we comparatively analyzed the cell surface phenotype of T-Cells obtained from BAL (BAL-T) and peripheral blood (PB-T) in twenty HIV-infected patients with pneumonitis. Samples derived from a control group of ten HIV (-) patients with non infectious miscellaneous lung disorders were as well analyze
- Mechanisms underlying the functional impairment of pulmonary nk cells from patients with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:428 (abstract no. Th.B.P.78). Unique Identifier : AIDSLINE ICA5/00218689
- Agostini C; Zambello R; Poletti V; Trentin L; Spiga L; Gritti F; Masciarelli M; Semenzato G; University of Padua, Padua, Italy
- OBJECTIVE: We previously demonstrated that in the lung of patients with AIDS NK cells are quantitatively increased but do not kill NK-sensitive cells (Am Rev Respir Dis 1988; 138:1609). To evaluate the mechanisms accounting for this functional impairment, lymphocytes recovered from the bronchoalveolar lavage (BAL) flu
- Alveolar macrophages from patients with HIV infection spontaneously release tumor necrosis factor.
- Int Conf AIDS. 1989 Jun 4-9;5:429 (abstract no. Th.B.P.79). Unique Identifier : AIDSLINE ICA5/00218789
- Agostini C; Trentin L; Poletti V; Zambello R; Spiga L; Gritti F; Feruglio C; Semenzato G; University of Padua, Padua Italy
- OBJECTIVE: To clarify whether HIV infection affects functional capabilities of alveolar macrophages (AM), AMs from bronchoalveolar lavage (BAL) of 6 patients with full-blown AIDS and 4 patients with ARC were examined for their ability to kill tumor necrosis factor (TNF)-susceptible tumor cells and to release TNF. METH
- Cd4 lymphocyte counts and serum p 24 antigen of no diagnostic value in monitoring HIV infected patients with pulmonary symptoms.
- Int Conf AIDS. 1989 Jun 4-9;5:429 (abstract no. Th.B.P.80). Unique Identifier : AIDSLINE ICA5/00218889
- Orholm M; Nielsen TL; Lundgren JD; Department of Infectious Diseases, Hvidovre Hospital, University; of Copenhagen, Denmark
- The aim of this study was to determine if the prognostic markers CD4 lymphocyte count and serum HIV p24 antigen were of any diagnostic value in HIV infected patients with pulmonary symptoms. METHOD: During 1987 and 1988 143 fiberoptic bronchoscopic procedures were performed on 104 HIV infected patients with pulmonary
- Immunological subtyping of leukocytes obtained from bronchoalveolar lavage (BAL) and peripheral blood in HIV-infected patients with pneumonia.
- Int Conf AIDS. 1989 Jun 4-9;5:429 (abstract no. Th.B.P.81). Unique Identifier : AIDSLINE ICA5/00218989
- Kagi MK; Fierz W; Kronauer C; Speich R; Russi E; Grob P; University Hospital, Zurich Switzerland
- OBJECTIVE: Recent reports have revealed that differential cell counts in bronchoalveolar lavages (BAL) of HIV-infected patients with pneumonia may provide important prognostic information. To further investigate these findings and to characterize the local immunological situation in the lungs we studied leukocytes of
- Cutaneous delayed hypersensitivity in drug addicts.
- Int Conf AIDS. 1989 Jun 4-9;5:429 (abstract no. Th.B.P.82). Unique Identifier : AIDSLINE ICA5/00219089
- Villa A; Cruccu V; Grondona C; Guareschi G; Pediconi AM; Confalonieri F; Fatebenefratelli Hospital, Milan, Italy
- OBJECTIVE: To evaluate the utility of cutaneous delayed hypersensitivity (CDH) tests in drug addicts (DA) and to apply them the Walter Reed Classification (WRC). METHODS: We studied 127 DA (95 male and 32 female), mean age 29 years; 60 HIV+ and 67 HIV-. Clinical examination, T4 and T8 counts and skin test (Multitest C
- Increased production of soluble IL 2 receptor in patients with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:429 (abstract no. Th.B.P.83). Unique Identifier : AIDSLINE ICA5/00219189
- Yokota Y; Kitamura K; Matsuda K; Mitsuyasu R; Chermann JC; Honda M; National Institute of Health, AIDS Research Center, Tokyo, Japan
- OBJECTIVE: To see whether the production of soluble IL 2 receptor (sIL 2R) in patients with HIV infection increases as the disease advances and correlates with other clinical parameters. METHODS: Two monoclonal antibodies against IL 2R were used for the fluorescence sandwich ELISA. Sera of patients with HIV infection
- Changes in cd-16 receptor expression on the neutrophils of HIV infected individuals.
- Int Conf AIDS. 1989 Jun 4-9;5:429 (abstract no. Th.B.P.84). Unique Identifier : AIDSLINE ICA5/00219289
- Boros P; Bekesi G; Roboz J; Unkeless JC; Mount Sinai School of Medicine, New York City, New York, USA
- OBJECTIVE: To examine changes in the expression of CD-16 receptor on the neutrophils from HIV infected individuals. METHODS: Leukocytes from whole blood samples from HIV infected individuals in various clinical stages and normal volunteers were double stained with mAb phycoerythrin-Leu 15 (anti CD11b) and fluorescein-
- Adenosine deaminase isoenzyme in retrovirus infected diseases.
- Int Conf AIDS. 1989 Jun 4-9;5:430 (abstract no. Th.B.P.85). Unique Identifier : AIDSLINE ICA5/00219389
- Yokoyama MM; Tsuboi I; Kurume University School of Medicine, Kurume, Fukuoka, Japan
- OBJECTIVE: ADA isoenzyme levels in sera of patients with adult T-cell leukemia (ATL) and acquired immunodeficiency syndrome (AIDS) were analysed. METHODS: Total ADA activity was determined by an enzyme spectrophotometric assay. ADA isoenzyme activity which was inhibited by erythro-9 (2-hydroxy-3 nonyl) adenine was des
- Cd4+/neopterin ratio correlates with p24 antigenaemia in HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:430 (abstract no. Th.B.P.86). Unique Identifier : AIDSLINE ICA5/00219489
- Paolo C; Lizioli A; Bedarida G; D'Agostino F; Cambie G; Cantaluppi P; Ospedale Maggiore -20075 Lodi (I) Italy
- OBJECTIVE: to verify the possible correlation between CD4/neopterin Ratio (R) and p24 antigenaemia (p24Ag) during HIV infection. METHODS: 72 patients (64 males, 8 females; mean age 24.2, range 18-33 years) were classified according to the WRSS criteria; they were also tested for p24Ag and serum neopterin levels (SNL);
- Lymphocyte reactivity to anti-cd3 as a prognostic marker in HIV-1 infected homosexual men.
- Int Conf AIDS. 1989 Jun 4-9;5:430 (abstract no. Th.B.P.87). Unique Identifier : AIDSLINE ICA5/00219589
- Roos M; Miedema F; de Wolf F; Lange J; Schellekens P; Central Lab. Netherl. Red Cross Blood Transf. Service and the; Lab. of Exp. and Clin Immunology of the Univ. of Amsterdam,; Amsterdam The Netherlands
- OBJECTIVE: In patients with ARC/AIDS, lymphocyte reactivity to antigens declines earlier and more severely compared to nonspecific mitogen responses. Because antigens stimulate T cells via the Ti/T3 complex we studied whether aCD3 reactivity followed the same pattern as antigen reactivity and could be used as a progno
- Neutrophil radical release and lipid peroxidation in HIV infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:430 (abstract no. Th.B.P.88). Unique Identifier : AIDSLINE ICA5/00219689
- Jarstrand C; Carlin G; Sonnerborg A; Akerlund B; Huddinge Hospital, Huddinge, Sweden
- INTRODUCTION: Since a transitory increase in Nitroblue tetrazolium (NBT)-reduction of neutrophils, reflecting an increased production of oxygen free radicals of these cells, has earlier been found during acute viral and bacterial infections a long term elevation in NBT-reduction was expected in the chronic HIV infecte
- Impairment of polymorphonucleocyte (PMN) chemotaxis and bactericidal function in HIV-infected children.
- Int Conf AIDS. 1989 Jun 4-9;5:430 (abstract no. Th.B.P.89). Unique Identifier : AIDSLINE ICA5/00219789
- Roilides E; Mertins S; Eddy J; Venzon D; Walsh T; Pizzo P; Rubin M; National Cancer Institute, Bethesda, Maryland, USA
- OBJECTIVE: HIV-infected children have an increased incidence of serious bacterial infections, which has been attributed to secondary abnormalities in immunoglobulins. Although PMN are the most important component of host defense against bacteria, PMN function in this group has not been assessed. Accordingly, we evalua
- Oxidative burst activity and cell surface antigen expression of monocytes from asymptomatic HIV infected individuals (AHI).
- Int Conf AIDS. 1989 Jun 4-9;5:430 (abstract no. Th.B.P.90). Unique Identifier : AIDSLINE ICA5/00219889
- Landay A; Kessler H; Benson C; Phair J; Rothberg LR; Spear G; Rush Medical Center, Chicago, IL, USA
- OBJECTIVE: To identify functional and phenotypic alterations of peripheral blood monocytes isolated from AHI. METHODS: Peripheral blood mononuclear cells were isolated on Ficoll Hypaque gradients. For oxidative burst measurements, cells were incubated with dichlorofluorescein-diacetate (DCFH-DA) and stimulated with ph
- Stratification of HLA alloantigens presenting cell function in patients with AIDS.
- Int Conf AIDS. 1989 Jun 4-9;5:431 (abstract no. Th.B.P.91). Unique Identifier : AIDSLINE ICA5/00219989
- Landay A; Clerici M; Kessler H; Shearer G; Rush Medical Center, Chicago, IL, USA
- OBJECTIVE: To test the ability of peripheral blood mononuclear cells (PBMC) from patients with AIDS to serve as stimulating cells as well as alloantigen presenting cells (APC) to responding PBMC from HIV seronegative (HIV-) donors. METHODS: HIV-, unfractionated PBMC or PBMC depleted of monocytes (PBL) by plastic and n
- In situ demonstration of il2 production in lymphnodes of HIV-1 positive patients with pgl.
- Int Conf AIDS. 1989 Jun 4-9;5:431 (abstract no. Th.B.P.92). Unique Identifier : AIDSLINE ICA5/00220089
- Peuchmaur M; Emilie D; Crevon MC; Delfraissy JF; Lemaigre G; Galanaud P; Hopital Antoine Beclere and INSERM U. 131, Clamart, France
- OBJECTIVE: Previous in vitro studies have demonstrated that HIV down-regulate the expression of IL2 gene. Using In Situ Hybridization (ISH) we studied in vivo IL2 mRNA expression in lymph nodes of Grade III (CDC) patients. The extent of this production should provide informations on the immunological status of such pa
- Variability in isotype-specific immunoglobulin (lg) secreting cells in asymptomatic HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:431 (abstract no. Th.B.P.93). Unique Identifier : AIDSLINE ICA5/00220189
- Spira T; Lee F; Nahmias A; Reimer C; Bozeman L; Neshelm S; Centers for Disease Control Atlanta, GA, USA
- OBJECTIVE: To compare the relative number of circulating isotype-specific lg secreting cells in asymptomatic HIV-infected and non-infected adults. METHODS: Peripheral blood mononuclear cells (PBMC) were assayed in 18 asymptomatic HIV infected and 19 negative adults. Isotype-specific lg-secreting cells were enumerated
- Impaired IgM production and mitogen-induced suppression of immunoglobulins by mononuclear cells from AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:431 (abstract no. Th.B.P.94). Unique Identifier : AIDSLINE ICA5/00220289
- Janoff EN; Smith PD; Wahl SM; National Institutes of Health, Bethesda, MD
- PURPOSE: To determine whether the inability of persons with AIDS to produce antibodies to new antigens, despite elevated levels of total immunoglobulins (Ig), is due to selective regulation of Ig classes. METHODS: We measured spontaneous and pokeweed mitogen (PWM) induced Ig production in vitro by peripheral blood mon
- Increased spontaneous release of CD8 antigen from CD8+ cells reflects the clinical progression of HIV-1 infected individuals.
- Int Conf AIDS. 1989 Jun 4-9;5:431 (abstract no. Th.B.P.95). Unique Identifier : AIDSLINE ICA5/00220389
- Chu F; Tsang PH; Robez JP; Wallace JI; Bekesi JG; The Mount Sinai School of Medicine, New York, NY, 10029, USA
- Associations were examined between selected phenotypic parameters, antibody response directed against HIV-1 and spontaneously released CD8 antigen (sCD8) in a cohort of 36 high risk HIV-1 (-) and 164 HIV-1 (+) homosexual males, 43 IVDA, 32 ARC and 36 AIDS patients, and 33 heterosexual controls. Marked increase in perc
- HIV and bone marrow progenitors proliferation.
- Int Conf AIDS. 1989 Jun 4-9;5:431 (abstract no. Th.B.P.96). Unique Identifier : AIDSLINE ICA5/00220489
- Pallavicini F; Antinori A; Tamburrini E; Candido A; Clin. Malattie Infettive, Italy
- OBJECTIVE: 1. To assess the proliferative capacity of granulocyte-macrophages progenitors cells (CFU-GM) from the bone marrow (BM) of AIDS patients and investigate the role of IL-1 and alpha-gp120 on this function; 2. to evaluate the effects of HIV-inactivated lysate (HIV-Lys) and conditioned medium obtained from cult
- Studies on the in vitro secretion of HIV1 specific antibodies by peripheral blood cells from HIV1 infected subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:432 (abstract no. Th.B.P.97). Unique Identifier : AIDSLINE ICA5/00220589
- Vendrell JP; Corbeau P; Ducos J; Reynes J; Huguet MF; Serre A; Cannat A; INSERM U65, Laboratoire d'Immunologie, Hopital Lapeyronie; Montpellier, France
- PBMC from 114 HIV1 seropositive subjects (73 asymptomatic, 15 ARC, 26 AIDS) and from 30 HIV1 negative controls were incubated: a) in the wells of the ELAVIA kit (Pasteur): the HIV1 antibodies secreted in vitro and fixed on the antigens were revealed by the use of a low noise enzymatic complex, b) in antigen free condi
- Enhanced endogenous tnf alpha production in peripheral blood mononuclear cells of HIV-1 infected patients.
- Int Conf AIDS. 1989 Jun 4-9;5:432 (abstract no. Th.B.P.98). Unique Identifier : AIDSLINE ICA5/00220689
- Rossol S; Voth R; Brunner S; Klein K; Buttner M; Muller WE; Meyer zum BuchenFelde KH; Hess GI; Med. Klinik und Poliklinik und Physiologisches Institut der; Johannes Gutenberg Universitat Mainz Federal Republic of Germany
- OBJECTIVE: To study the role of TNF-alpha in HIV-1 infected patients. METHODS: Blood samples positive for HIV-1 were obtained from 150 patients at various stages of disease. Peripheral blood mononuclear cells (PBMC) were isolated by Ficoll-Paque and stimulated with various inducers for TNF-alpha production. TNF-alpha
- Normal and HIV associated fungicidal activity of monocytes.
- Int Conf AIDS. 1989 Jun 4-9;5:432 (abstract no. Th.B.P.99). Unique Identifier : AIDSLINE ICA5/00220789
- Tamburrini E; Antinori A; Morace G; Manzara S; Ortona L; Ist. Clin. Malattie Infettive, Italy
- OBJECTIVE: i) to evaluate the ability of monocytes (M) and monocyte-derived macrophages (m-dM) of AIDS patients to kill Candida albicans and the role of rIFN-Gamma in their activation, and ii) to study the effect of HIV-lysate (HIV-lys) on M and m-dM fungicidal activity in healthy individuals (normals). METHODS: Ten A
- [Augmentation of the production of oxygen free radicals by circulating blood phagocytes in patients infected with the HIV virus]
- Int Conf AIDS. 1989 Jun 4-9;5:432 (abstract no. Th.B.P.100). Unique Identifier : AIDSLINE ICA5/00220889
- Vuitton DA; Didier JM; Vuillier J; Bertrand MA; Centre Hospitalier Regional et Universitaire, F-25030 Besancon,; France
- Refractoriness of B cells to regulation by lgl in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:432 (abstract no. Th.B.P.101). Unique Identifier : AIDSLINE ICA5/00220989
- Echeverria de Perez G; Deibis L; Ramirez R; Rios Z; de Marquez M; Blanca I; Bianco NE; Clinical Immunology National Center (WHO/SAS/UCV), Caracas; Venezuela
- CD3-, CD16+ large granular lymphocytes (LGL) behave as helper cells of immunoglobulin (Igs) synthesis by peripheral blood lymphocytes (PBMC), as measured in culture supernatants by ELISA. We evaluated such capability in 21 HIV+ individuals (11 of group II and 10 with AIDS), 12 HIV negative homosexuals (HM) and 11 hete
- Activated T-cells (TC) and human immunodeficiency virus (HIV) progression.
- Int Conf AIDS. 1989 Jun 4-9;5:432 (abstract no. Th.B.P.102). Unique Identifier : AIDSLINE ICA5/00221089
- Freeman T; Boswell RN; Hensley RE; Butzin C; US Air Force HIV Program, Lackland AFB, San Antonio, Texas, USA
- HYPOTHESIS: HIV is a retrovirus (RV) tropic for CD4+ cells. Proliferation of RV requires the translation and transcription of the host genome and cellular activation. Activation of TC should correlate with progression of HIV infection. One marker of TC activation is the production of HLA class II (DR) antigens (AG) wh
- Decreased lymphocyte proliferation towards pokeweed mitogen appears as a very early marker in HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:433 (abstract no. Th.B.P.103). Unique Identifier : AIDSLINE ICA5/00221189
- Huygen K; Fairon Y; Henrivaux P; Instituut Pasteur van Brabant, 1180 Brussels
- OBJECTIVE: To assess the immune function among HIV infected patients regarding the clinical stage of disease. METHODS: Using a whole blood assay, we have examined thirty-six HIV+ subjects for their in vitro lymphoproliferation towards Phytohaemagglutinin (PHA) and Pokeweed mitogen (PWM), and for their interferon produ
- In vitro B cell differentiation in normals, rgp160 vaccinated volunteers, and HIV+ subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:433 (abstract no. Th.B.P.104). Unique Identifier : AIDSLINE ICA5/00221289
- Reuben J; Liang L; Li S; Greenberg S; Smith G; Couch R; University of Texas, MD Anderson Cancer Center, Houston, TX
- OBJECTIVE: To determine B cell differentiation to HIV. METHODS: Peripheral blood mononuclear cells from asymptomatic HIV+ (SF), normals (HIV-) and rGP160 vaccine subjects were cultured on days 0, 14, 28, 44, and 194 post-vaccination with rGP160 antigen or HTLV-IIIB virus for 7 days at which time, supernatants were har
- Usefulness of lymphoblastic transformation test (L.T.T.) in asymptomatic patients (II and III status of CDC classification).
- Int Conf AIDS. 1989 Jun 4-9;5:433 (abstract no. Th.B.P.105). Unique Identifier : AIDSLINE ICA5/00221389
- Beuscart C; Coget A; Sivery B; Leroy O; Mouton Y; Fourrier A; CISIH - NORD - C.H. Tourcoing - France
- OBJECTIVE: Evaluation of Lymphoblastic Transformation Test (L.T.T.) in asymptomatic HIV positive patients. METHODS: For 74 clinically asymptomatic or with chronical lymphadenopathy patients, having a 18 months follow-up, a LTT (phytohemagglutinin, pokeweed, concavanalin A) was undertaken every 6 months. RESULTS: This
- Impact of 3'-azido-3'-deoxythymidine (AZT) on the in vitro immunoglobulin secretion in a pokeweed mitogen-driven cell system.
- Int Conf AIDS. 1989 Jun 4-9;5:433 (abstract no. Th.B.P.106). Unique Identifier : AIDSLINE ICA5/00221489
- Tauris P; Petersen CM; M:oller B; Dept. of Clinical Immunology, the Tissue Typing Laboratory,; University of Aarhus, Aarhus, Denmark
- OBJECTIVE: To study the impact of AZT on replication and Ig-secretion in in vitro-cultures of HIV-positive and -negative subjects. METHODS: Proliferation and distribution of surface markers was assessed by the 3H-thymidine technique and flow-cytometry
- Inhibition of lymphocyte proliferation induced by microbial antigens in HIV infected individuals.
- Int Conf AIDS. 1989 Jun 4-9;5:433 (abstract no. Th.B.P.107). Unique Identifier : AIDSLINE ICA5/00221589
- Rui V; Maria VA; Pinto LA; Faculty of Medicine of Lisbon - Department of Medicine 2, Av.; Prof. Egas Moniz, 1600 Lisbon, Portugal
- Patients with HIV infection have depressed cell mediated immune responses to microbial antigens. We did 20 studies in HIV seropositive subjects and in 25 normal individuals to assess lymphocyte responses in vitro to four different antigens (Tetanus Toxoid-TT, Escherichia Coli-EC,
- Estimation of best absolute cd4 count from multiple pairings in two-color flow cytometry.
- Int Conf AIDS. 1989 Jun 4-9;5:433 (abstract no. Th.B.P.108). Unique Identifier : AIDSLINE ICA5/00221689
- Niland JC; Participating institutions in New York City, Miami, Detroit,; Seattle, San Francisco, and Los Angeles
- OBJECTIVE: To evaluate 2 methods of estimating the absolute CD4 count when different values are obtained due to more than 1 pairing with other monoclonals. METHODS: In a longitudinal observational study of transfusion-associated HIV-1 infection, immunologic phenotyping is performed by two-color flow cytometry using a
- Identification of multiple HIV-1 core proteins on Western blots by a monoclonal antibody.
- Int Conf AIDS. 1989 Jun 4-9;5:434 (abstract no. Th.B.P.109). Unique Identifier : AIDSLINE ICA5/00221789
- Liang C; Henry S; Epstein JS; Center for Biologics Evaluation and Research, FDA, Bethesda, MD,; USA
- OBJECTIVE: To characterize the HIV-1 core proteins on Western blots. METHODS: Female BALB/c mice were immunized with partially purified HIV-1 proteins. Hybridomas secreting monoclonal antibodies (mAbs) were produced by fusing P3X63Ag8 653 myelomas with the splenocytes of the immunized mice and screened by enzyme-linke
- Evaluation of sensitivity and specificity of synthetic peptide and recombinant based ANT-HIV1&2 EIA.
- Int Conf AIDS. 1989 Jun 4-9;5:434 (abstract no. Th.B.P.110). Unique Identifier : AIDSLINE ICA5/00221889
- Joller HI; University Hospital, Zurich, Switzerland
- The first generation of anti-HIV screening assays, introduced shortly after the discovery of HIV, were based on virus lysate. They did thus react to all antibodies directed towards various proteins in the HIV1, but cross-reacted also to impurities in the celline. To overcome problems of cross-reactivity and to enable
- Development of a method for correlating the presence of HIV antigen and provirus.
- Int Conf AIDS. 1989 Jun 4-9;5:434 (abstract no. Th.B.P.111). Unique Identifier : AIDSLINE ICA5/00221989
- Paul DB; Bankowski M; Kuhns M; McNamara A; Landay AL; Spear GT; Rush University, Chicago, IL, USA
- OBJECTIVE: a) To develop a sensitive flow cytometric assay that will allow detection of HIV antigen containing cells. b) To correlate the presence of HIV antigen with provirus in cells. METHODS: Cell lines were fixed, permeabilized, and stained for HIV antigens with a variety of fluorescent antibodies. After staining,
- Human immunodeficiency virus (HIV) expression and antigenic stability of HIV-infected cells for use in flow cytometric immunofluorescence assay (FIFA).
- Int Conf AIDS. 1989 Jun 4-9;5:434 (abstract no. Th.B.P.112). Unique Identifier : AIDSLINE ICA5/00222089
- Sligh JM; Roodman ST; Knutsen AP; Tsai CC; St. Louis University School of Medicine, St. Louis, MO, USA
- The Flow Cytometric Immunofluorescence Assay (FIFA) detects antibodies to Human Immunodeficiency Virus (HIV) with high sensitivity and specificity compared to ELISA and Western blot (WB). The FIFA is an indirect immunofluorescence assay that uses live HIV-infected H9 cells (HIV-H9) and is analyzed by flow cytometry. F
- [Immunodosage type ELISA of differentiation CD4 and CD8 antigens of lymphocytes from healthy or HIV virus infected subjects]
- Int Conf AIDS. 1989 Jun 4-9;5:434 (abstract no. Th.B.P.113). Unique Identifier : AIDSLINE ICA5/00222189
- Carriere D; Fontaine C; Rabesandratana H; Serre A; Vendrell JP; Andary M; Clot J; Brunet C; Sanpol J; Lagrange MC; et al; Sanofi Recherches, Montpellier, France
- Simple laboratory tests as markers for the various clinical manifestations of HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:434 (abstract no. Th.B.P.114). Unique Identifier : AIDSLINE ICA5/00222289
- Greco DB; Paulino UW; Adams MI; Victoria MA; Pra:ca CL; Castro CC; Immunodeficiency Clinic, Infectious and Parasitic Diseases; Service, Faculty of Medicine, Federal University of Minas Gerais,; Belo Horizonte, Brazil
- OBJECTIVE: To study the correlation between laboratory tests and clinical manifestations of HIV infection. METHODS: From February 86 to May 88 we have evaluated 549 individuals who spontaneously came to the clinic due to risky behaviour, with symptoms of HIV infection or anxiety related to the AIDS epidemic. One hundr
- Comparison of the simultaneous administration of intradermal (ID) and merieux multitest cmi (MM) skin test methods in HIV1 seropositive patients.
- Int Conf AIDS. 1989 Jun 4-9;5:435 (abstract no. Th.B.P.115). Unique Identifier : AIDSLINE ICA5/00222389
- Mayers D; Goodman DL; Wagner KF; Ebbeling WL; National Naval Med. Center, Bethesda, MD
- OBJECTIVES: To compare skin test results using the ID method with results from the MM method using individual patients (pts) as their own controls. METHODS: Skin tests were applied simultaneously to the volar surfaces of both forearms on 68 HIVI seropositive patients. The ID panel was placed on the right forearm and c
- Phenotypic analysis of lymphocyte subsets in a diffuse infiltrative lymphocytosis syndrome (DILS) associated with HIV infection.
- Int Conf AIDS. 1989 Jun 4-9;5:435 (abstract no. Th.B.P.116). Unique Identifier : AIDSLINE ICA5/00222489
- Itescu S; Brancato J; Dalton J; Perdue R; Winchester R; Hospital for Joint Diseases, NYU Medical Center, New York, NY,; USA
- OBJECTIVE: To characterize a Sjogren s syndrome-like disorder in HIV-infected individuals with circulating and diffuse infiltrative CD8 lymphocytosis associated with HLA-DR5 (DILS) and to determine whether particular lymphocyte subsets are selectively expanded. METHODS: Patients were ascertained by referral for clinic
- Antibodies to sulfamethoxazole (SMX) in normal, allergic, HIV infected, and AIDS patients.
- Int Conf AIDS. 1989 Jun 4-9;5:435 (abstract no. Th.B.P.117). Unique Identifier : AIDSLINE ICA5/00222589
- Sullivan TJ; Davidson R; Budens R; Nightingale S; University of Texas Southwestern Medical Center, Dallas, Texas,; USA
- OBJECTIVE: To establish assays for antibodies to sulfonamides. To determine the prevalence of IgG, IgA, IgM, and IgE antibodies to SMX in the blood of normal control subjects, SMX allergic patients, and randomly selected HIV+ and AIDS patients. To identify univalent haptens capable of inhibiting antibody binding to SM
- HIV-infected subjects respond to polio vaccination booster according to absolute T4 cell count.
- Int Conf AIDS. 1989 Jun 4-9;5:435 (abstract no. Th.B.P.118). Unique Identifier : AIDSLINE ICA5/00222689
- Vardinon N; Handsher R; Zackut V; Burke M; Hasner A; Yust I; Clinical Immunology Unit, Tel Aviv Medical Center, Israel
- HIV infection is known to impair both cellular and humoral immunity. We studied the immunity to Polio virus in homosexual HIV-infected patients by measuring the level of antibodies against polio virus before and after i.m. booster vaccination with Salk Poliomyelitis vaccine (Connaught). 16 HIV seropositive homosexuals
- The effect of vaccination against hepatitis B on the cd4+ cell count in anti-HIV positive men.
- Int Conf AIDS. 1989 Jun 4-9;5:435 (abstract no. Th.B.P.119). Unique Identifier : AIDSLINE ICA5/00222789
- Gutfreund K; Cheatham-Speth D; Rossol S; Voth R; Clemens R; Hess G; First Medical Department, University of Mainz, D-6500 Mainz, FRG
- OBJECTIVE: HBsAg may activate T-Cells as indicated by gamma interferon production. The effect of vaccination against hepatitis B on the CD4+ cell count in anti-HIV positive individuals was investigated to elucidate whether there might be a detrimental effect on the progression of HIV disease. METHODS: 13 anti-HIV posi
- Immunologic aspects of multiple simultaneous vaccination in HIV seropositive subjects.
- Int Conf AIDS. 1989 Jun 4-9;5:435 (abstract no. Th.B.P.120). Unique Identifier : AIDSLINE ICA5/00222889
- Rhoads J; Birx D; Redfield R; Burke DS; Walter Reed Retrovirus Research Group, Washington, DC, USA
- OBJECTIVE: To identify immunologic factors predictive of response to immunization by HIV seropositive subjects, and to evaluate the effect of vaccination on the activation of T and B cells. METHODS: 21 asymptomatic HIV seropositive subjects who had received multiple vaccines were evaluated for vaccine response and imm