ORAL MANIFESTATIONS OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION

Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

ORAL MANIFESTATIONS OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION

Infect Dis Ther; 3:143-52 1989. Unique Identifier : AIDSLINE ICDB/90665443
Greenspan D; Greenspan JS; Div. of Oral Medicine, Dept. of Stomatology, Sch. of Dentistry,; Univ. of California, San Francisco, CA

Abstract: Oral manifestations of AIDS and AIDS-related complex were described in the very first reports of these syndromes. There is growing evidence that several otherwise relatively innocuous oral opportunistic infections occurring in patients with HIV infection are indicators of marked immunosuppression and may predict the ultimate development of AIDS. Fungal and bacterial oral lesions, virus-associated oral lesions, gingivitis and periodontal disease, and miscellaneous oral lesions seen in patients with HIV infection are described and illustrated in six color figures. Topics include oral candidiasis, mycobacterial infections, human papillomaviruses, herpes simplex, herpes zoster, cytomegalovirus, oral hairy leukoplakia, Epstein-Barr virus, recurrent aphthous ulcers, and salivary gland enlargement. Hairy leukoplakia is a remarkable lesion because it is unique to people infected with HIV, having never been seen before the AIDS epidemic. It is a significant clinical marker of HIV infection and may be one of the early changes associated with infection. Oral examination is an important part of any physical examination, and nowhere is this more important than with suspected HIV infection. All mucosal surfaces should be assessed using a mouth mirror, examination gloves, gauze squares for tongue extension, and an adequate light source. (33 Refs)

Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS/DIAGNOSIS Biopsy Human HIV Infections/*COMPLICATIONS/DIAGNOSIS Leukoplakia, Oral/COMPLICATIONS Microscopy, Electron Mouth Mucosa/PATHOLOGY Mouth Neoplasms/*COMPLICATIONS/DIAGNOSIS Opportunistic Infections/*COMPLICATIONS/DIAGNOSIS Stomatitis/*COMPLICATIONS/DIAGNOSIS Tumor Virus Infections/COMPLICATIONS JOURNAL ARTICLE REVIEW, TUTORIAL REVIEW
901030
M90A0692

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1990. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1990. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .