1990

AIDS, current medical and legal aspects. [sound recording]
Sherman Oaks, CA : The Institute, c1987 7 sound cassettes (90 min. each) : 1 7/8 ips + 1 guide Unique Identifier : AIDSLINE AV/9001093A
Barrios G
Acquired immune deficiency syndrome, the San Francisco General Hospital approach. [videorecording]
Secaucus, N.J. : Network for Continuing Medical Education, 1987 1 videocassette (32 min.) : sd., col. ; 3/4 in. + 1 booklet (NCME telecourse ; no. 508) Unique Identifier : AIDSLINE AV/9001160A
Clement M; Fahrner R
The story of this model care delivery system, at the San Francisco General Hospital Medical Center, which strives to make AIDS a treatable outpatient disease, is told in the words of its staff physicians, nurses, social workers, volunteers, and patients they serve on Ward 5-A (the Inpatient Unit) of the hospital and W


Nutritional aspects of the AIDS patient. [videorecording]
[Los Angeles, Calif.] : Hospital Satellite Network, c1988 1 videocassette (30 min.) : sd., col. with b&w ; 1/2 in Unique Identifier : AIDSLINE AV/9001150A
Gordon AN; Brodie H
(Producer) Program covers the most up to date information available for health care professionals involved in assessing and providing nutritional support for AIDS patients. Nutritional support begins with a careful dietary history that details clinical problems interfering with food intake and nutrient utilization.


AIDS and sexual practice : frank questions, candid answers. [videorecording]
Secaucus, N.J. : Network for Continuing Medical Education, c1988 1 videocassette (17 min.) : sd., col. ; 3/4 in. + 1 booklet (NCME telecourse ; no. 521) Unique Identifier : AIDSLINE AV/9001164A
Neu HC; Storch ML
A dialogue between two specialists in the fields of infectious diseases and of obstetrics and gynecology presents counseling approaches to patients questions and concerns about the retrovirus and the safety of heterosexual, bisexual, and same-sex intercourse.


Infants and children with AIDS. [videorecording]
Secaucus, N.J. : Network for Continuing Medical Education, 1988 1 videocassette (30 min.) : sd., col. ; 3/4 in. + 1 booklet (NCME telecourse ; no. 517) Unique Identifier : AIDSLINE AV/9001181A
Boland M; Oleske JM
Presents a pioneering team approach to AIDS in infants and children, in five succinct sections: basic facts, differential diagnosis and course of illness, hospitalization, ambulatory services and home care, and special family concerns.


Legal and policy issues. [slide]
[Columbus, Ohio : Ohio Medical Education Network, 1989] 29 slides : col. + 1 sound cassette (1 7/8 ips) + 1 guide (OMEN ; no. 26A) Unique Identifier : AIDSLINE AV/9001077A
McDermott J; Dye CF
AIDS in rural America. [videorecording]
[Scranton, Pa.] : WVIA-TV, c1989 1 videocassette (28 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9001092A
(Producer) Focuses on the social, psychological aspects of addressing AIDS in the rural communities of America. Confronts an important aspect of coping with the AIDS virus, since the prevailing attitude in the U.S. is that AIDS is essentially a city disease and not of consequences in the outlying areas, which is not


Living with HIV infection : nursing implications. [slide]
[Columbus, Ohio : Ohio Medical Education Network, 1989] 31 slides : col. + 1 sound cassette (1 7/8 ips) + 1 guide (OMEN ; no. 22A) Unique Identifier : AIDSLINE AV/9001147A
Coleman DA; Neidig J
Mother, mother. [videorecording]
[S.l.] : Micki Dickoff, c1989 1 videocassette (34 min., 47 sec.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9001192A
Armstrong B; Dickoff M
AIDS, facing the challenge. [videorecording]
Spokane, Wash. : Sacred Heart Medical Center, c1990 1 videocassette (29 min.) : sd., col. ; 1/2 in. + 1 guide Unique Identifier : AIDSLINE AV/9001094A
Wilson D; Butler M; Collins JB
AIDS, what everyone needs to know. 2nd revision. [videorecording]
Los Angeles, CA : Churchill Films, c1990 1 videocassette (19 1/2 min.) : sd., col. with b&w ; 1/2 in Unique Identifier : AIDSLINE AV/9001139A
Arnold W; Loya R; Francis DP; Wolfe P
(Producer) Animation and live action detail on how the AIDS virus works, risky and safe behaviors, and new advances in the diagnosis and management of AIDS. Dramatic interviews with AIDS-infected teens, women, heterosexuals and minorities make this revision valuable to all groups in society.


AIDS information.
Leeds, U.K. : Oncology Information Service [and] Leeds University Press, v Unique Identifier : AIDSLINE CAT/9013226
[SIDA e relacoes sexuais : que perigos.]
Lisboa, Portugal : Europress, c1986 63 p. : ill (Divulgacao e ciencia ; 2) Unique Identifier : AIDSLINE CAT/9013361
[A:SIDA desmascarada.] 1a ed.
[Portugal] : Polemos Grupo Editorial, 1987 158 p (Coleccao Saude) Unique Identifier : AIDSLINE CAT/9013360
Teles FR
Report of the Meeting on Criteria for HIV Screening Programmes, Geneva, 20-21 May 1987.
[Geneva] : World Health Organization, [1987] 12 p Unique Identifier : AIDSLINE CAT/9013685
[AIDS : como combater, vinte e uma informacoes para a comunidade ou tecnico-cientificas para profissionais da area da saude.]
AIDS [Sao Paulo?] : Paris Editorial, 1988 73 p. : ill (Colecao Problemas da saude) Unique Identifier : AIDSLINE CAT/9013227
[Rechtsprobleme von AIDS : HIV-Test, Infektion, Behandlung, Versicherung.]
Bergisch Gladbach : Eul, c1988 33 p (Schriftenreihe / Kolner Juristische Gesellschaft ; Bd. 5) Unique Identifier : AIDSLINE CAT/9013681
Deutsch E
Third International Conference on AIDS and Associated Cancers in Africa : final programme : September 14-16, 1988, Arusha International Conference Centre, Arusha, Tanzania.
[Dar es Salaam] : The Association, [1988- v. : ill Unique Identifier : AIDSLINE CAT/9013363
AIDS clinical digest.
Atlanta, GA : American Health Consultants, c1988- v Unique Identifier : AIDSLINE CAT/9013760
California AIDS Clearinghouse reviewer. Vol. 1, no. 1 (summer 1988)-
Santa Cruz, CA : The Clearinghouse, [1988- v. : ill Unique Identifier : AIDSLINE CAT/9013772
[Dilemma's rondom AIDS.]
Amsterdam : Swets & Zeitlinger, c1989 208 p. : ill Unique Identifier : AIDSLINE CAT/9013045
Vuijsje H
[Nature contre SIDA.]
Geneve : Editions Soleil, c1989 278 p. : ill Unique Identifier : AIDSLINE CAT/9013122
Comby B
AIDS and your rights. Rev. ed.
Canberra, ACT : Australian Federation of AIDS Organisations, 1989 27 p. : ill Unique Identifier : AIDSLINE CAT/9013225
AIDS : a guide to research resources. Rev. and enl. ed.
[Berkeley, Calif.] : The Library, University of California at Berkeley, c1989 ii, 63 leaves Unique Identifier : AIDSLINE CAT/9013228
Lindsay T; Klugman S
Guide to resources, e.g., books, conferences, databases, articles, government documents, journals, audiovisuals, and organizations. Arranged by topics or formats. Entries give identifying and descriptive information. Glossary. Miscellaneous appendixes.


HIV seropositivity and AIDS prevention and control : report of a WHO meeting, Moscow, 14-17 March 1989.
Control Copenhagen : World Health Organization, Regional Office for Europe, c1989 vi, 33 p Unique Identifier : AIDSLINE CAT/9013284
Macquarie University and AIDS : the report of the AIDS Working Party. Rev. ed.
Sydney : Macquarie University, c1989 xii, 65 p Unique Identifier : AIDSLINE CAT/9013304
Monitoring of national AIDS prevention and control programmes : guiding principles.
Geneva : World Health Organization, 1989 iii, 27 p. : ill (WHO AIDS series, ISSN 1011-5773 ; 4) Unique Identifier : AIDSLINE CAT/9013318
[AIDS als Versuchung : christliche Existenz und schwere Krankheit.] Originalausg.
Munchen : Kaiser, c1989 178 p (Kaiser Taschenbucher, ISSN 0931-7732 ; 55) Unique Identifier : AIDSLINE CAT/9013442
Walter A
AIDS : policies and programs for the workplace.
New York : Van Nostrand Reinhold, c1989 xiii, 305 p. : ill Unique Identifier : AIDSLINE CAT/9013443
Brown KC; Turner JG
Viral proteinases as targets for chemotherapy.
Cold Spring Harbor, N.Y. : Cold Sring Harbor Laboratory, c1989 xv, 287 p. : ill (Current communications in molecular biology) Unique Identifier : AIDSLINE CAT/9013726
Krausslich H; Oroszlan S; Wimmer E
Women and AIDS : initiatives of the Public Health Service : a report of the PHS Coordinating Committee on Women's Health Issues, 1987.
Women's Health Issues [Washington, D.C.] : Public Health Service : For sale by Supt. of Docs., U.S. G.P.O., [1989?] 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9013732
Mycoses in AIDS patients.
New York : Plenum Press, c1990 xi, 337 p. : ill Unique Identifier : AIDSLINE CAT/9013120
Bossche Hv
The:myth of heterosexual AIDS.
New York : Basic Books, c1990 xv, 411 p. : ill Unique Identifier : AIDSLINE CAT/9013205
Fumento M
Medi-Cal studies in AIDS. No. 1-
[Sacramento, Calif.] : The Department, 1990- v. : ill Unique Identifier : AIDSLINE CAT/9013110
Infectious risks in surgery.
Norwalk, Conn. : Appleton & Lange, c1991 ix, 294 p. : ill Unique Identifier : AIDSLINE CAT/9013550
Howard RJ
Skin Langerhans (dendritic) cells in virus infections and AIDS.
Boston : Kluwer Academic Publishers, c1991 xiv, 320 p. : ill (Developments in medical virology ; DIMV7) Unique Identifier : AIDSLINE CAT/9013704
Becker Y
The:geography of AIDS : origins and course of an epidemic.
New York : Guilford Press, c1991 vii, 192 p. : ill Unique Identifier : AIDSLINE CAT/9013384
Shannon GW; Pyle GF; Bashshur R
MOLECULAR PROBES: TECHNOLOGY AND MEDICAL APPLICATIONS
Molecular Probes: Technology and Medical Applications. Albertini A et al, eds. New York, Raven Press, 292 p., 1989.. Unique Identifier : AIDSLINE ICDB/90665379
Anonymous; No affiliation given
The future success of biotechnology depends on the continued willingness of scientists in different areas to share their findings and knowledge. This volume facilitates the exchange of results between biologists and clinicians. It includes contributions from the International Symposium BIOTECH RIA 88, which was held


OPPORTUNISTIC INFECTIONS IN PATIENTS WITH THE ACQUIRED IMMUNODEFICIENCY SYNDROME
Infect Dis Ther; 3:1-445 1989. Unique Identifier : AIDSLINE ICDB/90665435
Anonymous; No affiliation given
Opportunistic infections are the paramount clinical problem confronting physicians caring for patients (pts) with AIDS. Pneumocystis carinii pneumonia alone accounts for 65% of index AIDS diagnoses, and over 80% of pts will have at least one episode. Opportunistic infections will dominate the clinical picture of HIV i


CUTANEOUS INFECTIONS IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION
Infect Dis Ther; 3:135-42 1989. Unique Identifier : AIDSLINE ICDB/90665442
Cockerell CJ; Friedman-Kien AE; Dept. of Dermatology, New York Univ. Medical Center, New York, NY
In many patients with HIV infection, cutaneous infections are the first manifestations of immunodeficiency. The spectrum of dermatologic manifestations ranges from widespread fulminant mucocutaneous eruptions to very subtle, localized skin lesions that often go unnoticed. Mucocutaneous infections that develop in patie


CYTOMEGALOVIRUS DISEASE IN ACQUIRED IMMUNODEFICIENCY DISEASE
Infect Dis Ther; 3:195-213 1989. Unique Identifier : AIDSLINE ICDB/90665446
Jacobson MA; Dept. of Medicine, San Francisco General Hosp., San Francisco, CA
Among the viral infections affecting patients (pts) with AIDS, cytomegalovirus ( CMV ) is the most common cause of life-threatening disease. Although prior CMV infection is found in 70-90% of the general population, serious dis


CRYPTOSPORIDIUM SPP AND ISOSPORA BELLI
Infect Dis Ther; 3:355-77 1989. Unique Identifier : AIDSLINE ICDB/90665454
Ma P; Dept. of Laboratories, St. Vincent's Hosp. and Medical Center of; New York, New York, NY
Cryptosporidium spp cause diarrhea in mammals, birds, fish, and reptiles. Human cryptosporidiosis was unheard of until 1976. Isospora belli is another coccidial protozoan, very rare in the United States , but known for many years as a parasite acquired in tropical countries where it is


GASTROINTESTINAL DISEASE: PATHOLOGY, DIAGNOSIS, MANAGEMENT. FOURTH EDITION
Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. Fourth Edition. Sleisenger MH and Fordtran JS, eds. Philadelphia, Saunders, 2027 p., 1989.. Unique Identifier : AIDSLINE ICDB/90665865
Anonymous; No affiliation given
This volume emphasizes the rational and effective management of the principal gastrointestinal diseases and disorders encountered in developed Western countries. In addition, contributors discuss current concepts of biology, human behavior, pathophysiology, pharmacology, and nutrition essential for understanding the b


ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS)
Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. Fourth Edition. Sleisenger MH and Fordtran JS, eds. Philadelphia, Saunders, p. 1233-42, 1989.. Unique Identifier : AIDSLINE ICDB/90665868
Masur H; Fauci AS; Clinical Center, NIH, Bethesda, MD
The AIDS virus causes a spectrum of clinical manifestations ranging from no symptoms and apparent health to severe symptoms and rapid death from one or more lethal tumors or infections. AIDS is reviewed under the following headings: definition; etiology; incidence and prevalence; epidemiology; pathogenesis; clinical m


GASTROINTESTINAL MANIFESTATIONS OF AIDS AND OTHER SEXUALLY TRANSMISSIBLE DISEASES
Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. Fourth Edition. Sleisenger MH and Fordtran JS, eds. Philadelphia, Saunders, p. 1242-80, 1989.. Unique Identifier : AIDSLINE ICDB/90665869
Friedman SJ; Owen RL; San Francisco General Hosp., San Francisco, CA
Gastrointestinal and hepatobiliary symptoms are among the most frequent complaints in patients (pts) with AIDS, and a methodical effort is required to identify those symptoms that are treatable. Best estimates suggest that 50-93% of all pts with AIDS will have marked gastrointestinal symptoms during the course of thei


LYMPHOMA/MYELOMA
Decision Making in Oncology. Schein PS, ed. Clinical Decision Making Series, Philadelphia, BC Decker, p. 16-25, 1989.. Unique Identifier : AIDSLINE ICDB/90665877
Anonymous; No affiliation given
Clinical decision making with regard to lymphomas and myelomas is considered in chapters covering Hodgkin s disease (HD), non-Hodgkin s lymphoma (NHL; low-grade histology), NHL (intermediate- or high-grade histology), cutaneous T-cell lymphoma, and multiple myeloma. For suspected H


NUCLEOTIDE ANALOGUES AS ANTIVIRAL AGENTS
ACS Symp Ser; (401):1-190 1989. Unique Identifier : AIDSLINE ICDB/90666471
Anonymous; No affiliation given
The amount of research directed toward the discovery and rational design of antiviral agents has grown dramatically over the last several years, largely in response to the AIDS epidemic. A symposium on nucleotide analogs as antiviral agents was held at the 196th National Meeting of the American Chemical Society, Septe


SYNTHESIS AND ANTIVIRAL ACTIVITY OF PHOSPHONYLMETHOXYETHYL DERIVATIVES OF PURINE AND PYRIMIDINE BASES
ACS Symp Ser; (401):72-102 1989. Unique Identifier : AIDSLINE ICDB/90666475
Bronson JJ; Kim CU; Ghazzouli I; Hitchcock MJ; Kern ER; Martin JC; Bristol-Myers Co., Pharmaceutical Res. and Development Div., 5; Research Parkway, Wallingford, CT 06492-7660
Acyclic nucleotide analogs having a common (2-phosphonylmethoxy)ethyl (PME) side chain attached to a purine or pyrimidine base were prepared and selected for in vivo studies based on in vitro antiviral activity against retroviruses and herpesviruses. The adenine derivative PMEA showed good in vitro activity against HI


DESIGN, SYNTHESIS, AND ANTIVIRAL ACTIVITY OF NUCLEOSIDE AND NUCLEOTIDE ANALOGUES
ACS Symp Ser; (401):140-55 1989. Unique Identifier : AIDSLINE ICDB/90666477
Marquez VE; Lab. of Medicinal Chemistry, NCI, Bethesda, MD 20892
Several categories of antiviral compounds have been designed by exploiting important differences in viral and cellular biochemistry, as well as differences in chemical stability and reactivity between parent lead molecules and their modified structures. The synthesis, antiviral activity and mechanism of action of tw


OLIGONUCLEOTIDE ANALOGUES AS POTENTIAL CHEMOTHERAPEUTIC AGENTS
ACS Symp Ser; (401):170-84 1989. Unique Identifier : AIDSLINE ICDB/90666479
Zon G; Applied Biosystems, Inc, 850 Lincoln Centre Drive, Foster City,; CA 94404
In principle, relatively short oligonucleotides (approx 15-20 bases in length) can specifically hybridize with DNA or RNA and thus be used for novel drug design strategies involving targeted interference of genetic expression at the level of transcription or translation. Conceivable chemotherapeutic applications predi


ANIMAL MODELS OF HUMAN VIRAL DISEASES: RELEVANCE TO DEVELOPMENTAL THERAPEUTICS
J Cell Biochem; (Suppl 14D):41-75 1990. Unique Identifier : AIDSLINE ICDB/90665935
Anonymous; No affiliation given
A symposium on the relevance of animal models of human viral diseases to developmental therapeutics, part of the UCLA series, was held in Keystone, Colorado, from March 31 to April 5, 1990. The symposium covered herpes simplex virus (HSV) and other herpesviruses; hepatitis virus; AIDS; papillomaviruses; respiratory vi


TISSUE TROPISM OF SIMIAN IMMUNODEFICIENCY VIRUS IN RHESUS MONKEYS
Diss Abstr Int [B]; 50(11):4994 1990. Unique Identifier : AIDSLINE ICDB/90666653
Wyand MS; Univ. of Connecticut
Simian immunodeficiency virus (SIV) is a T-lymphotropic lentivirus that is genetically, immunologically, and morphologically related to the human immunodeficiency viruses type 1 and 2 (HIV-1, HIV-2). In rhesus monkeys, SIV induces a progressively fatal immunodeficiency syndrome strikingly similar to human acquired imm


PHOSPHONYLMETHYL ETHERS OF NUCLEOSIDES AND THEIR ACYCLIC ANALOGUES
ACS Symp Ser; (401):51-71 1989. Unique Identifier : AIDSLINE ICDB/90666474
Holy' A; De Clercq E; Votruba I; Inst. of Organic Chemistry and Biochemistry, Czechoslovak Academy; of Sciences, 166 10 Praha 6, Czechoslovakia
Structure-activity investigation in the series of acyclic nucleotide analogs bearing a modified phosphoric acid residue at the side-chain revealed two novel classes of antivirals: N-(3-hydroxy-2-phosphonylmethoxypropyl)- (HPMP-) and N-(2-phosphonylmethoxyethyl)- (PME-) derivatives of heterocyclic bases. Adenine, guani


NUCLEOTIDE DIMERS AS ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENTS
ACS Symp Ser; (401):156-69 1989. Unique Identifier : AIDSLINE ICDB/90666478
Hahn EF; Busso M; Mian AM; Resnick L; IVAX Corporation, 8800 NW 36th Street, Miami, FL 33178
A series of nucleotide homo- and heterodimers was synthesized from nucleosides which include azidothymidine, 2 ,3 -dideoxyadenosine and 2 ,3 -dideoxyinosine. The compounds were evaluated with respect to anti-HIV activity, cytotoxicity, in vitro stability, and in vivo distribution. On an equimolar basis, greater anti-H


Acquired immune deficiency syndrome.
Tex Nurs. 1983 Aug;57(7):12-3. Unique Identifier : AIDSLINE MED/90357226
Children with AIDS: a special dilemma.
Mass Nurse. 1985 Dec;55(12):1, 4. Unique Identifier : AIDSLINE MED/90348447
Moon MW
[Epidemiologic and clinical study of HIV in jails: personal experience]
Riv Eur Sci Med Farmacol. 1988 Feb;10(1):27-31. Unique Identifier : AIDSLINE MED/90333002
Ginaldi L; Magnanimi G; Catena G; De Angelis S
[Treatment with aztreonam of gram negative infections in patients seropositive for HIV]
Riv Eur Sci Med Farmacol. 1988 Aug;10(4):317-21. Unique Identifier : AIDSLINE MED/90333016
Catania S; Mascellino MT; Trinchieri V; Musso R; Lorenzi A; Cirelli A
AIDS in children: the slaughter of innocents [letter]
Riv Eur Sci Med Farmacol. 1988 Aug;10(4):340. Unique Identifier : AIDSLINE MED/90333020
Cantani A
[AIDS and asymptomatic HIV seropositivity at the Hopital Prinicipal. Epidemiological and clinical aspects]
Dakar Med. 1988;33(1-4):45-51. Unique Identifier : AIDSLINE MED/90345805
Barabe P; Peghini M; Griffet P; Jean P; Mbaye PS; Wade B; Philippon G; Morcillo R; Digoutte JP; Leguenno B; et al
Blood donors to be screened for cancer virus [news]
Oncology (Huntingt). 1988 Oct;2(10):38. Unique Identifier : AIDSLINE MED/90351946
Legislation related to acquired immune deficiency syndrome.
State Nurs Legis Q. 1987 Fall;5(1):16-7. Unique Identifier : AIDSLINE MED/90357129
Human immunodeficiency virus: strategies for protection and therapy.
Microbiol Sci. 1988 Oct;5(10):300-2. Unique Identifier : AIDSLINE MED/90329325
Boyd JE; James K; Department of Surgery, Edinburgh University Medical School, UK.
Never before has so much been learned about the molecular biology of a virus in such a short time since its discovery and yet effective strategies for fighting the human immunodeficiency virus that causes AIDS remain elusive. This review and the accompanying colour centrespread outline some of the options available at


Microbial contaminants and antimicrobial properties of human milk.
Microbiol Sci. 1988 Feb;5(2):42-6. Unique Identifier : AIDSLINE MED/90344371
May JT; Microbiology Department, La Trobe University, Bundoora, Victoria,; Australia.
A review and listing of antibacterial, antiviral and antiparasite factors in human breast milk is presented. Also reviewed are the microbial contaminants such as cytomegalovirus and rubella virus, which have recently been shown to infect infants via breast milk, without adverse eff


Two new pepsin proteases of microbial origin [news]
Microbiol Sci. 1988 Jun;5(6):190-1. Unique Identifier : AIDSLINE MED/90344399
Pugsley AP
Recent advances in pediatric dermatology.
Adv Dermatol. 1987;2:107-26. Unique Identifier : AIDSLINE MED/90344455
Treadwell PA; Department of Dermatology, Indiana University Medical Center,; Indianapolis.
Transfusion safety: minimal risk of AIDS remains despite HIV antibody testing.
Oncology (Huntingt). 1988 Oct;2(10):12-3, 16, 19. Unique Identifier : AIDSLINE MED/90351944
Menitove JE; Blood Center, Southeastern Wisconsin, Milwaukee.
[Immunological aspects of AIDS]
Dtsch Krankenpflegez. 1988 Mar;41(3):164-6. Unique Identifier : AIDSLINE MED/90329967
Gerlach A
[Epidemiology and clinical aspects of acquired immunodeficiency syndrome (AIDS)]
Dtsch Krankenpflegez. 1988 Mar;41(3):167-71. Unique Identifier : AIDSLINE MED/90329968
von Keyserlingk-Eberius HJ
[Nursing of AIDS patients]
Dtsch Krankenpflegez. 1988 Mar;41(3):172-4. Unique Identifier : AIDSLINE MED/90329969
Wottke A; Regitz M
[Report on the state of nursing of patients with AIDS in the hospital]
Dtsch Krankenpflegez. 1988 Mar;41(3):174-6. Unique Identifier : AIDSLINE MED/90329970
Klee B
[The discussion group AIDS and Humanity]
Dtsch Krankenpflegez. 1988 Mar;41(3):176-8. Unique Identifier : AIDSLINE MED/90329971
Bresien J; Mutczalla A
[The AIDS-Help, Cologne and its Mobile Care Center]
Dtsch Krankenpflegez. 1988 Mar;41(3):179-80. Unique Identifier : AIDSLINE MED/90329972
Sohnle H
[The psychosocial situation and counseling of AIDS patients and HIV-positives. Experiences from the hospital social service]
Dtsch Krankenpflegez. 1988 Mar;41(3):181-5. Unique Identifier : AIDSLINE MED/90329973
Bohnke B; Kretschmer-Flemming B
[Chaplaincy on an AIDS ward]
Dtsch Krankenpflegez. 1988 Mar;41(3):184-8. Unique Identifier : AIDSLINE MED/90329974
Eibach U; Schneider B
[Our approach to AIDS and the HIV infected]
Dtsch Krankenpflegez. 1988 Mar;41(3):188-91. Unique Identifier : AIDSLINE MED/90329975
Canaris U
[Preventive measures against occupational HIV infection. Recommendations for workers in the health services]
Dtsch Krankenpflegez. 1988 Mar;41(3):192-3. Unique Identifier : AIDSLINE MED/90329976
Dinse S
[The child with HIV infection and the child with AIDS]
Dtsch Krankenpflegez. 1988 Mar;41(3):200-4. Unique Identifier : AIDSLINE MED/90329978
Wahn V
[Juridical questions about AIDS]
Dtsch Krankenpflegez. 1988 Mar;41(3):204-9. Unique Identifier : AIDSLINE MED/90329979
Eberbach W
[The recognition of AIDS as an occupational disease]
Dtsch Krankenpflegez. 1988 Mar;41(3):210-1. Unique Identifier : AIDSLINE MED/90329980
Mehrtens G
[Encounters with dying AIDS patients. Chances of psychosocial care of severely ill and dying patients with AIDS]
Dtsch Krankenpflegez. 1988 Jan;41(1):29-33. Unique Identifier : AIDSLINE MED/90336501
Bieberstein R
Legislation related to acquired immune deficiency syndrome.
State Nurs Legis Q. 1987 Winter;5(2):29-30. Unique Identifier : AIDSLINE MED/90357135
Protection for the health care worker--care of the AIDS patient.
Oreg Nurse. 1987 Oct;52(3):15. Unique Identifier : AIDSLINE MED/90349219
Moore J
Government estimates on AIDS too high, says Stanford expert [news]
Oncology (Huntingt). 1988 Nov;2(11):34. Unique Identifier : AIDSLINE MED/90351958
Dentists' attitudes toward mandatory screening of dental personnel for infectious diseases and the continued practice of infected dental personnel.
J Law Ethics Dent. 1989 Jul-Dec;2(3-4):199-203. Unique Identifier : AIDSLINE MED/90325068
Cohen LA; Grace EG Jr
The issues surrounding mandatory screening of dental personnel for infectious diseases and the rights of infected dental personnel to continue to practice are beginning to receive greater attention. In order to examine Maryland dentists attitudes on these issues, a mail survey of all Maryland dentists was conducted.


Infection control. Survey of dental health care workers.
Oral Health. 1989 Oct;79(10):53-6. Unique Identifier : AIDSLINE MED/90326370
Epstein JB; Rathee NN; Mathias RG
HIV and the dental undergraduate.
Stoma (Lisb). 1989;2(14):7-9, 12-3. Unique Identifier : AIDSLINE MED/90327246
Smithurst BA; Russell JG
Reasons are offered as to why it is imperative that the dental undergraduate is familiar with all aspects of AIDS. The epidemiology of the disease is discussed, as are methods of transmission of the virus. A classification is given of the clinical presentation of HIV infection. The classification is based on the syste


The HIV-infected dental professional. A challenge to law, ethics, and the dental profession.
J Dent Pract Adm. 1989 Oct-Dec;6(4):162-8. Unique Identifier : AIDSLINE MED/90331000
Logan MK
This article explores the legal and ethical dilemmas posed when a dental professional becomes infected with the AIDS virus. The author addresses existing ethics policies of professional associations, the importance of evaluating the risk of exposure to patients, informed consent, and regulatory issues. The paper also


State of knowledge about AIDS among seamen as well as the spreading of HIV in this occupational group.
Bull Inst Marit Trop Med Gdynia. 1989;40(1-2):57-66. Unique Identifier : AIDSLINE MED/90335481
Goethe WH; Schmitz H; Vuksanovic P; Perisic S; Bernhard Nocht Institute for Nautical and Tropical Diseases,; Hamburg, FRG.
In the period from March 1, 1987 until October 31, 1988, 873 seamen were examined on HIV and questioned on their state of knowledge on AIDS. A questionnaire with 7 questions on AIDS and 6 important features of the seamen was statistically evaluated. This evaluation showed the following results: 22% of all persons ques


[Risk of transmission of hepatitis B at a dental department. (Review)]
Prakt Zubn Lek. 1989 Aug;37(8):239-42. Unique Identifier : AIDSLINE MED/90341145
Trojan P; Trojanova A
The authors present a general characteristic of hepatitis B and its possible transmission at a dental department. They draw attention to the analogy in the mechanism of transmission of hepatitis B and AIDS. In the prevention they emphasize the urgency to use surgical gloves.


[Psychological approach to the infection problem]
Attual Dent. 1989 Sep 17;5(31):10-1. Unique Identifier : AIDSLINE MED/90344027
Falcioni S; Gambetti M
[Risk factors in operating]
Attual Dent. 1989 Nov 5;5(38):32-3. Unique Identifier : AIDSLINE MED/90344051
Zerbinati A; Gandolfo A; Zerbinati M; Mangiante S
[Infection control in orthodontics: infective agents and modality of transmission. 1]
Mondo Ortod. 1989 Sep-Oct;14(5):615-20. Unique Identifier : AIDSLINE MED/90348647
Garattini G; Bersani E; Moruzzi E
Adequate attention to prevention of cross-contamination in dental operatory is largely ignored by orthodontists. This occurs for two principal reasons. The first one is that orthodontic patients, usually children, are erroneously considered a low-risk population. The second one is that orthodontic procedures are usual


Implication for research of the 1988 Anti-Drug Abuse Act.
NIDA Res Monogr. 1989;95:16-22. Unique Identifier : AIDSLINE MED/90348757
Schuster CR; National Institute on Drug Abuse, Rockville, MD 20857.
A tale of three cities: risk taking among intravenous drug users.
NIDA Res Monogr. 1989;95:378-9. Unique Identifier : AIDSLINE MED/90348830
Booth R; Brewster JT; Koester S; Wiebel WW; Fritz R; University of Colorado Health Sciences Center, Department of; Psychiatry, Denver.
HIV risk behavior: antisocial personality disorder, drug use patterns, and sexual behavior among methadone maintenance admissions.
NIDA Res Monogr. 1989;95:401-2. Unique Identifier : AIDSLINE MED/90348843
Nolimal D; Crowley TJ; Department of Psychiatry, University of Colorado School of; Medicine, Denver 80262.
Primary medical care for IVDU's: a model for future care.
NIDA Res Monogr. 1989;95:403-4. Unique Identifier : AIDSLINE MED/90348844
Schottenfeld RS; O'Connor PG; Yale University School of Medicine.
HIV-infected i.v. drug users in methadone treatment: outcome and psychological correlates--a preliminary report.
NIDA Res Monogr. 1989;95:405-6. Unique Identifier : AIDSLINE MED/90348845
Batki SL; Sorensen JL; Gibson DR; Maude-Griffin P
Mode of HIV transmission among seroconverted intravenous drug users (IVDUs): 1987 and 1988 cohort study.
NIDA Res Monogr. 1989;95:407-8. Unique Identifier : AIDSLINE MED/90348846
Nemoto T; Brown LS Jr; Primm BJ; Foster K; Chu A; Addiction Research and Treatment Corporation, Brooklyn, NY.
Developmental decline in infants born to HIV-infected intravenous drug-using mothers.
NIDA Res Monogr. 1989;95:409-10. Unique Identifier : AIDSLINE MED/90348847
Kletter R; Jeremy RJ; Rumsey C; Weintrub P; Cowan M; University of California, San Francisco.
Does fear of AIDS affect behavior of addicts?
NIDA Res Monogr. 1989;95:411-2. Unique Identifier : AIDSLINE MED/90348848
Schottenfeld RS; O'Malley SS; Abdul-Salaam K; Yale University School of Medicine.
Demographic, behavioral and clinical features of HIV infection in NYC intravenous drug abusers.
NIDA Res Monogr. 1989;95:413-4. Unique Identifier : AIDSLINE MED/90348849
Brown LS Jr; Chu A; Nemoto T; Primm BJ; Division of Research and Medical Affairs, Addiction Research and; Treatment Corporation, Brooklyn, NY.
Psychiatric symptoms in HIV test consenters and refusers.
NIDA Res Monogr. 1989;95:415-6. Unique Identifier : AIDSLINE MED/90348850
Woody G; Metzger DS; McLellan AT; O'Brien CP; DiPhilipis D; Center for Studies on Addiction, University of; Pennsylvania/Philadelphia VA Medical Center.
Addict beliefs about access to HIV test results.
NIDA Res Monogr. 1989;95:417. Unique Identifier : AIDSLINE MED/90348851
Calsyn DA; Freeman G Jr; Saxon AJ; Whittaker S; Veterans Affairs Medical Center, University of Washington,; Seattle.
Needle obtainment and cleaning habits of addicts.
NIDA Res Monogr. 1989;95:418. Unique Identifier : AIDSLINE MED/90348852
Saxon AJ; Calsyn DA; Whittaker S; Freeman G Jr; Veterans Affairs Medical Center, University of Washington,; Seattle.
Genesis of New York City's experimental needle exchange program: getting a denigrated group on the government agenda.
NIDA Res Monogr. 1989;95:419-20. Unique Identifier : AIDSLINE MED/90348853
Gillman CL; Narcotic and Drug Research, Inc., New York, N. Y. 10025.
Human immunodeficiency virus and viral hepatitis seroepidemiology in New York City intravenous drug abusers (IVDAs).
NIDA Res Monogr. 1989;95:443-4. Unique Identifier : AIDSLINE MED/90348868
Brown LS Jr; Kreek MJ; Trepo C; Chu A; Banks SE; Valdes M; Ajuluchukwu D; Phillips R; Primm BJ; Division of Research and Medical Affairs, Addiction Research and; Treatment Corporation, Brooklyn, NY.
Stress and emotional distress as possible co-factors in the development of AIDS in a sample of intravenous drug users.
NIDA Res Monogr. 1989;95:445-6. Unique Identifier : AIDSLINE MED/90348869
Catan V; Narcotic and Drug Research, Inc., New York, NY 10013.
Intravenous heroin use: its association with HIV infection in patients in methadone treatment.
NIDA Res Monogr. 1989;95:447-8. Unique Identifier : AIDSLINE MED/90348870
Chu A; Brown LS; Banks S; Nemoto T; Primm BJ; Addiction Research and Treatment Corporation, Brooklyn, NY.
Precarious dilemmas: mobilizing blacks against AIDS.
NIDA Res Monogr. 1989;95:473-4. Unique Identifier : AIDSLINE MED/90348887
Quimby E; Howard University Washington, D.C. 20079.
Needle-sharing patterns as a predictor of HIV seroprevalence among New York City intravenous drug users (IVDUs).
NIDA Res Monogr. 1989;95:488-9. Unique Identifier : AIDSLINE MED/90348895
Yee K; Brown LS; Primm BJ; Nemoto T; Foster K; Division of Research and Medical Affairs, Addiction Research and; Treatment Corporation, Brooklyn, N.Y.
NIDA's Medication Development Program--1989.
NIDA Res Monogr. 1989;95:64-73. Unique Identifier : AIDSLINE MED/90348939
Schuster CR; Snyder M; National Institute on Drug Abuse, Rockville, Maryland 20857.
[Neuropathology of the acquired immunodeficiency syndrome]
Pathologica. 1989 Sep-Oct;81(1075):481-98. Unique Identifier : AIDSLINE MED/90349371
Casadei GP; Barberis M; Oreste PL; Caggese L; Schlacht I
Neuropathology of acquired immunodeficiency syndrome. The Central Nervous System (CNS) has been examined at autopsy in 60 patients who died of AIDS in a 6-year period in our hospital. Most of the patients were intravenous drug abusers, the mean age was of 34 years, with a high prevalence of males. Neurologic symptoms


Disclosure of HIV antibody status: behavioral and mental health correlates.
AIDS Educ Prev. 1989 Spring;1(1):1-11. Unique Identifier : AIDSLINE MED/90351689
Ostrow DG; Joseph JG; Kessler R; Soucy J; Tal M; Eller M; Chmiel J; Phair JP; AIDS Psychobiology Study Unit, University of Michigan, Ann Arbor; 48106.
How black and Latino community organizations respond to the AIDS epidemic: a case study in one New York City neighborhood.
AIDS Educ Prev. 1989 Spring;1(1):12-21. Unique Identifier : AIDSLINE MED/90351690
Freudenberg N; Lee J; Silver D; Center for Community Action to Prevent AIDS, Hunter College; School of Health Sciences, New York, NY 10010.
AIDS and women: remaining ethical issues.
AIDS Educ Prev. 1989 Spring;1(1):22-30. Unique Identifier : AIDSLINE MED/90351691
Bell NK; Department of Philosophy, University of South Carolina, Columbia; 29208.
Personal service workers: a critical link in the AIDS education chain?
AIDS Educ Prev. 1989 Spring;1(1):31-8. Unique Identifier : AIDSLINE MED/90351692
Backinger C; Department of Health and Human Services, Public Health Service,; Food & Drug Administration, Rockville, MD 20857.
Based on the hepatitis B experience in these PSW occupations, it is possible to transmit HIV through instruments, materials, and equipment used by PSWs. However, PSWs include a group of people that may be overlooked when planning and conducting AIDS education programs because they do not fit into a well defined and ap


Innovative educational strategies and recommendations for AIDS prevention and control.
AIDS Educ Prev. 1989 Spring;1(1):53-6. Unique Identifier : AIDSLINE MED/90351694
Sy FS; Richter DL; Copello AG; University of South Carolina, School of Public Health, Columbia; 29208.
Perspectives on AIDS in Africa: strategies for prevention and control.
AIDS Educ Prev. 1989 Spring;1(1):57-69. Unique Identifier : AIDSLINE MED/90351695
Airhihenbuwa CO; Department of Health Education, Pennsylvania State University,; University Park 16802.
Prevention of human immunodeficiency virus infection among adolescents: the interplay of health education and public policy in the development and implementation of school-based AIDS education programs.
AIDS Educ Prev. 1989 Spring;1(1):70-8. Unique Identifier : AIDSLINE MED/90351696
DiClemente RJ; Department of Epidemiology & International Health, School of; Medicine, University of California, San Francisco 94143-0560.
Charleston declaration on AIDS education, counseling and prevention. International Society for AIDS Education, Second International Conference on AIDS Education, August 2-4, 1988, Charleston, South Carolina, USA.
AIDS Educ Prev. 1989 Spring;1(1):79-80. Unique Identifier : AIDSLINE MED/90351697
Responding to AIDS: ten principles for the workplace.
AIDS Educ Prev. 1989 Spring;1(1):80-1. Unique Identifier : AIDSLINE MED/90351698
Levine C
AIDS education for family planning service providers [news]
AIDS Educ Prev. 1989 Spring;1(1):82. Unique Identifier : AIDSLINE MED/90351699
The First International Interdisciplinary Course on AIDS [news]
AIDS Educ Prev. 1989 Spring;1(1):82. Unique Identifier : AIDSLINE MED/90351700
Sy FS
AIDS education in Brazil [news]
AIDS Educ Prev. 1989 Spring;1(1):82-3. Unique Identifier : AIDSLINE MED/90351701
Coalition for AIDS education in east Tennessee [news]
AIDS Educ Prev. 1989 Spring;1(1):83. Unique Identifier : AIDSLINE MED/90351702
Mobilizing against AIDS in southwest USA [news]
AIDS Educ Prev. 1989 Spring;1(1):83. Unique Identifier : AIDSLINE MED/90351703
The health outreach team: taking AIDS education and health care to the streets.
AIDS Educ Prev. 1989 Summer;1(2):105-18. Unique Identifier : AIDSLINE MED/90351704
Froner G; Rowniak S
Ambiguities and scares in educational material about AIDS.
AIDS Educ Prev. 1989 Summer;1(2):119-25. Unique Identifier : AIDSLINE MED/90351705
Wyatt HV; Department of Community Medicine, University of Leeds, United; Kingdom.
To embrace the messenger: connections in three plays about AIDS.
AIDS Educ Prev. 1989 Summer;1(2):126-33. Unique Identifier : AIDSLINE MED/90351706
Carter AH 3d; Nixon LL; Eckerd College, St. Petersburg, FL 33733.
An evaluation of AIDS prevention brochures for university women and men.
AIDS Educ Prev. 1989 Summer;1(2):134-40. Unique Identifier : AIDSLINE MED/90351707
D'Augelli AR; Kennedy SP; Department of Individual and Family Studies, Pennsylvania State; University, University Park 16802.
Targeting AIDS through information, education, and communications programs: implications for Africa and the Caribbean.
AIDS Educ Prev. 1989 Summer;1(2):154-62. Unique Identifier : AIDSLINE MED/90351709
Ward WB; College of Public Health, University of South Florida, Tampa; 33612.
San Francisco AIDS Foundation offers consulting programs [news]
AIDS Educ Prev. 1989 Summer;1(2):164. Unique Identifier : AIDSLINE MED/90351712
Bart M
The Citizens Commission on AIDS: a leadership response to the AIDS crisis [news]
AIDS Educ Prev. 1989 Summer;1(2):164-5. Unique Identifier : AIDSLINE MED/90351713
Levine C
The AIDS quilt: a powerful educational tool [news]
AIDS Educ Prev. 1989 Summer;1(2):165. Unique Identifier : AIDSLINE MED/90351714
Locklair M
AIDS exhibition at the National Museum of Health & Medicine [news]
AIDS Educ Prev. 1989 Summer;1(2):165-6. Unique Identifier : AIDSLINE MED/90351715
Pinsker S
Public health students' knowledge of AIDS: implications for HIV-related training needs.
AIDS Educ Prev. 1989 Summer;1(2):89-95. Unique Identifier : AIDSLINE MED/90351717
Richwald GA; Sekler JC; Kitimbo DW; Friedland JM; UCLA School of Public Health 90024-1772.
Towards an AIDS information strategy for Zimbabwe.
AIDS Educ Prev. 1989 Summer;1(2):96-104. Unique Identifier : AIDSLINE MED/90351718
Wilson D; Wilson C; Greenspan R; Sibanda P; Msimanga S; Psychology Department, University of Zimbabwe, Mount Pleasant,; Harare.
Designing interventions to prevent HIV-1 infection by promoting use of condoms and spermicides among intravenous drug abusers and their sexual partners.
AIDS Educ Prev. 1989 Fall;1(3):171-83. Unique Identifier : AIDSLINE MED/90351719
Stone AJ; Morisky D; Detels R; Braxton H; School of Public Health, UCLA 90024-1772.
This paper summarizes the results of a 2-day workshop to identify the most effective educational strategies to promote use of condoms and spermicides for preventing heterosexual transmission of HIV-1 virus from intravenous drug abusers (IVDA) to their steady, nonintravenous drug abusing (NIVDA) sexual partners. Repres


Factors associated with hospital workers' reactions to the treatment of persons with AIDS.
AIDS Educ Prev. 1989 Fall;1(3):184-93. Unique Identifier : AIDSLINE MED/90351720
Pomerance LM; Shields JJ; Washington Hospital Center, DC 20010.
This article reports on how the increasing number of AIDS patients is having a significant impact on the delivery of healthcare services. Healthcare workers need to learn how to provide medical care for persons with AIDS as well as how to interact with and relate to them. Workers who have accurate information regardin


Methods for the reduction of AIDS social anxiety and social stigma.
AIDS Educ Prev. 1989 Fall;1(3):194-221. Unique Identifier : AIDSLINE MED/90351721
Bean J; Keller L; Newburg C; Brown M; Department of Psychology, Stockton State College, Pomona, NJ; 08240-9988.
A cognitive-social model is proposed for the study of AIDS social attitudes. Features of the ambivalent (fear and compassion) public belief system toward PWAs are outlined and ways to increase altruism and reduce fear are specified. Three studies are reported using cognitive-social methods for the reduction of AIDS so


Development of an instrument to measure attitudes toward acquired immune deficiency syndrome.
AIDS Educ Prev. 1989 Fall;1(3):222-30. Unique Identifier : AIDSLINE MED/90351722
Shrum JC; Turner NH; Bruce KE; Northeast Georgia Family Medical Center, Inc., Colbert, GA 30628.
The AIDS Attitude Scale (AAS) was developed to measure attitudes toward acquired immune deficiency syndrome (AIDS) among college students. In phase one, 67 items, determined by an expert panel to have content validity, were randomly ordered and administered to 164 student volunteers in a large southern university. Fif


AIDS and drug use: breaking the link. Citizens Commission on AIDS for New York City and northern New Jersey.
AIDS Educ Prev. 1989 Fall;1(3):231-46. Unique Identifier : AIDSLINE MED/90351723
Levin C; Citizens Commission on AIDS, New York, NY 10013.
The effect of terminology on public consciousness related to the HIV epidemic.
AIDS Educ Prev. 1989 Fall;1(3):247-50. Unique Identifier : AIDSLINE MED/90351724
Gayle JA; Department of Adult Counseling, Health and Vocational Education,; Kent State University, OH 44242-0001.
Language, as a reflection of culture, not only mirrors the concepts of the society in which it is employed, but also shapes the consciousness of the people who communicate with it. Recently acquired terminology related to AIDS has had a dramatic effect upon American perceptions and traditions. Current suggestions that


The National AIDS Information Clearinghouse [news]
AIDS Educ Prev. 1989 Fall;1(3):253-5. Unique Identifier : AIDSLINE MED/90351725
LouLou D
School boards and HIV prevention education for youth [news]
AIDS Educ Prev. 1989 Fall;1(3):255-6. Unique Identifier : AIDSLINE MED/90351726
Greene BZ
NSBA publishes report on the need for AIDS education [news]
AIDS Educ Prev. 1989 Fall;1(3):256-7. Unique Identifier : AIDSLINE MED/90351727
Smith P
NIAID AIDS Clinical Trials Information Service established [news]
AIDS Educ Prev. 1989 Fall;1(3):257-8. Unique Identifier : AIDSLINE MED/90351728
Who hasn't heard about AIDS?
AIDS Educ Prev. 1989 Winter;1(4):261-7. Unique Identifier : AIDSLINE MED/90351729
Albrecht GL; Levy JA; Sugrue NM; Prohaska TR; Ostrow DG; School of Public Health, University of Illinois, Chicago 60680.
This article analyzes who among the general population has not heard about AIDS despite intensive educational programs and widespread media attention about the syndrome. The data are drawn from a survey of the general public s knowledge, attitudes, and behavior toward AIDS in May-July, 1987 to establish a baseline for


A preliminary investigation using drama in community AIDS education.
AIDS Educ Prev. 1989 Winter;1(4):268-76. Unique Identifier : AIDSLINE MED/90351730
Probart CK; Department of Health Science Education, University of Florida,; Gainesville 32611.
This investigation assessed the impact of drama on AIDS-related knowledge and beliefs of selected individuals in a university community. Subjects were 136 members of the audience attending two performances of As Is, the award-winning drama by William Hoffman depicting the illness and inevitable death of a homosexual m


AIDS fears and homophobia among rural nursing personnel.
AIDS Educ Prev. 1989 Winter;1(4):277-84. Unique Identifier : AIDSLINE MED/90351731
D'Augelli AR; Pennsylvania State University, University Park 16802.
Attitudes and concerns about AIDS of 144 nursing personnel attending conferences on AIDS in rural central Pennsylvania were assessed. Participants were knowledgeable about AIDS but wished to learn more and wanted additional training. Most were moderately worried about contracting AIDS, and a sizeable percentage showed


Mental health care providers: the need for AIDS education.
AIDS Educ Prev. 1989 Winter;1(4):285-90. Unique Identifier : AIDSLINE MED/90351732
Knox MD; Dow MG; Cotton DA; Department of Community Mental Health, FMHI, University of South; Florida, Tampa 33612-3899.
Mental health care providers completed a set of measures assessing their attitudes, knowledge, and beliefs concerning AIDS. Those surveyed were aware of the main transmission routes but were excessively concerned about casual contact. Most indicated that they are not competent to deal with AIDS patients and would pref


A bridge to treatment: the needle exchange pilot program in New York City.
AIDS Educ Prev. 1989 Winter;1(4):340-5. Unique Identifier : AIDSLINE MED/90351736
Joseph SC
The needle exchange pilot program in New York City is one element in a spectrum of drug prevention and treatment modalities under way to slow the spread of the human immunodeficiency virus. The program s aim is to help us learn about the addict behaviors that spread the AIDS virus, including whether needle exchange ca


ISAE elects officers and council members [news]
AIDS Educ Prev. 1989 Winter;1(4):346. Unique Identifier : AIDSLINE MED/90351737
Nixon L
The Community Research Initiative of New York [news]
AIDS Educ Prev. 1989 Winter;1(4):346-7. Unique Identifier : AIDSLINE MED/90351738
Holzemer SP; Hannan T
AZT benefits HIV-positive asymptomatic people: new hope, new challenges [news]
AIDS Educ Prev. 1989 Winter;1(4):347. Unique Identifier : AIDSLINE MED/90351739
Lewis A
The Third International Conference on AIDS education, September 10-13, 1989, Nashville, Tennessee, USA.
AIDS Educ Prev. 1989 Winter;1(4):348. Unique Identifier : AIDSLINE MED/90351740
Harris VL
International Society for AIDS Education 1989 resolutions [news]
AIDS Educ Prev. 1989 Winter;1(4):349. Unique Identifier : AIDSLINE MED/90351741
Copello AG
The role of cachectin/tumor necrosis factor in AIDS.
Cancer Cells. 1989 Oct;1(2):62-3. Unique Identifier : AIDSLINE MED/90351776
Tracey KJ; Cerami A; Laboratory of Medical Biochemistry, Rockefeller University, New; York, New York 10021.
Alpha interferon approved for AIDS-related Kaposi's sarcoma [news]
Oncology (Huntingt). 1989 Jan;3(1):105. Unique Identifier : AIDSLINE MED/90351995
FDA approves wider use of aerosolized pentamidine to prevent pneumocystis pneumonia [news]
Oncology (Huntingt). 1989 Mar;3(3):54. Unique Identifier : AIDSLINE MED/90352036
AIDS: public response to a telephone information system.
J Cancer Educ. 1989;4(4):265-9. Unique Identifier : AIDSLINE MED/90352173
Michalek AM; Markello SJ; Mirand EA; Roswell Park Memorial Institute, Buffalo 14263.
This article reports on Roswell Park Memorial Institute s experience with a taped, telephone information system in the dissemination of informational and educational messages to the public concerning cancer and AIDS. This system, known as CAN-DIAL, has serviced over 400,000 callers since its inception in 1973. A serie


[Discussion on AIDS at the annual world congress of the F.D.I.]
Dent Cadmos. 1989 Dec 15;57(19):88, 91. Unique Identifier : AIDSLINE MED/90353673
[Assistance to patients with AIDS (editorial)]
Rev Cubana Med Trop. 1989 Sep-Dec;41(3):319-20. Unique Identifier : AIDSLINE MED/90333065
Perez Avila J
Colony-stimulating factors in the treatment of HIV-associated non-Hodgkin's lymphoma.
Oncology (Huntingt). 1989 Oct;3(10):79-83; discussion 84-6. Unique Identifier : AIDSLINE MED/90335052
Walsh C; Division of Oncology, Kaplan Cancer Center, New York University.
Treatment results using standard chemotherapeutic regimens for patients with intermediate and high-grade non-Hodgkin s lymphoma have been disappointing. For patients with HIV-associated lymphoma, whose bone marrow tolerance is so limited, conservative dose combination chemotherapy


[Oral manifestations in patients infected with human immunodeficiency virus]
Pract Odontol. 1989 Oct;10(10):41-4, 46-50. Unique Identifier : AIDSLINE MED/90341138
Delgado Azanero W; Mosqueda Taylor A; Gotuzzo Herencia E; Sanchez J
This study describes the stomatological findings reported on 20 Peruvian patients infected by the human AIDS virus. Lesions occurring most frequently were: xerostoma (80%), pseudomembranous candidiasis (70%), commissural cheilitis (55%), atrophy of filiform papillae (40%), ulcerative lesions (30%), vellous leucoplasia


[The eye and AIDS]
Ophtalmologie. 1989 May;3 Suppl 1:5-90. Unique Identifier : AIDSLINE MED/90349325
Katlama C
Fear of AIDS: issues for health professional education.
AIDS Educ Prev. 1989 Spring;1(1):39-52. Unique Identifier : AIDSLINE MED/90351693
Gerbert B; Maguire B; Badner V; Altman D; Stone G; University of California, School of Dentistry, Department of; Dental Public Health and Hygiene, San Francisco, CA 94143.
Minority AIDS prevention: moving beyond cultural perspectives towards sociopolitical empowerment.
AIDS Educ Prev. 1989 Summer;1(2):141-53. Unique Identifier : AIDSLINE MED/90351708
De La Cancela V; Department of Mental Health, Dr. Solomon Carter Fuller Mental; Health Center, Boston, MA 02118-2389.
First comprehensive survey of worldwide anti-AIDS efforts published [news]
AIDS Educ Prev. 1989 Summer;1(2):163. Unique Identifier : AIDSLINE MED/90351710
Worthington GM
The first international AIDS education directory [news]
AIDS Educ Prev. 1989 Summer;1(2):163. Unique Identifier : AIDSLINE MED/90351711
Allen HF
The Health Belief Model in understanding compliance with preventive recommendations for AIDS: how useful?
AIDS Educ Prev. 1989 Winter;1(4):303-23. Unique Identifier : AIDSLINE MED/90351734
Montgomery SB; Joseph JG; Becker MH; Ostrow DG; Kessler RC; Kirscht JP; Department of Epidemiology, School of Public Health, University; of Michigan, Ann Arbor 48109.
The Health Belief Model (HBM) has been applied to a variety of health conditions: most are less threatening and require less complex responses than those arising in the case of AIDS. The utility of the HBM in understanding preventive behaviors in AIDS is examined in a cohort of homosexual men at two different time poi


The impact of AIDS on state public health legislation in the United States: a critical review.
AIDS Educ Prev. 1989 Winter;1(4):324-39. Unique Identifier : AIDSLINE MED/90351735
Lamboi SE; Sy FS; Department of Epidemiology and Biostatistics, University of South; Carolina School of Public Health, Columbia 29208.
This article reviews and analyzes the current public health legislation in 17 states and the District of Columbia in the United States . These states were selected and grouped into high, medium, and low incidence based on their annual AIDS incidence rates. Data were collected through a


Pediatric lung disease.
Curr Opin Radiol. 1989 Dec;1(4):557-62. Unique Identifier : AIDSLINE MED/90351829
Wood BP; University of Rochester Medical Center, New York.
Life insurance and HIV testing: insurance theory, discrimination and solutions.
Med Law. 1989;8(6):567-80. Unique Identifier : AIDSLINE MED/90331638
Bergkamp L
Part 1 describes briefly how the market for life insurance deals with HIV infection and how society has reacted to its policies. Part 2 examines the arguments for and against HIV testing: does it discriminate against individuals or is it just a logical extension of risk estimation procedures and underwriting technique


Hormone reduces levels of AIDS virus in blood [news]
Oncology (Huntingt). 1989 Oct;3(10):19. Unique Identifier : AIDSLINE MED/90335046
[First meeting of the Work Group for Care of AIDS patients and their families]
Dtsch Krankenpflegez. 1989 Sep;42(9):633. Unique Identifier : AIDSLINE MED/90353151
[Nursing of AIDS patients. Vote 18 ot the National AIDS Advisory Board from 12 April 1989]
Dtsch Krankenpflegez. 1989 Sep;42(9):633-4. Unique Identifier : AIDSLINE MED/90353152
Eberbach WH
AIDS and HIV-1 infection: clinical entities in geriatric dentistry.
Gerodontology. 1989 Spring;8(1):27-32. Unique Identifier : AIDSLINE MED/90330309
Ship JA; Wolff A
The number of AIDS cases in individuals 50 years of age or older in the United States is reported to exceed 9000. Contaminated blood and blood transfusions are major contributors to HIV-1 infection in this age group. Sexual transmission and infection through intravenous drug abuse are


[Bullous toxic skin disease with fatal outcome in AIDS (letter)]
Presse Med. 1989 Oct 21;18(34):1708-9. Unique Identifier : AIDSLINE MED/90341163
Caumes E; Feyeux C; Garrouste MT; Schlemmer B; Wallach D
[Prognostic aspects of persistent adenopathies in human immunodeficiency virus infections (letter)]
Presse Med. 1989 Oct 21;18(34):1710-1. Unique Identifier : AIDSLINE MED/90341167
Morlat P; Msellati P; Dupon M; Pellegrin JL; Lacoste D
[HIV-positive newborns via maternal-fetal transmission. Early ophthalmic lesions]
Ophtalmologie. 1989 Jan-Mar;3(1):77-8. Unique Identifier : AIDSLINE MED/90349250
Costet C; Baechler-Sadoul E; Gramet C; Manassero J; Deville A; Lagier J
Since January 1986, the authors have examined twenty infant HIV positives. In two cases specially, some serious and precocious ophthalmic lesions have been found : an ophthalmic zona appeared at the age of three months, a cytomegalovirus retinitis diagnosed at the age of six months


NIMH seeks research on AIDS and mental health [news]
AIDS Educ Prev. 1989 Summer;1(2):166. Unique Identifier : AIDSLINE MED/90351716
Stover E
AZT/ddC combination may benefit AIDS sufferers [news]
Oncology (Huntingt). 1989 Jan;3(1):107. Unique Identifier : AIDSLINE MED/90351997
[Bilateral white lesions of the tongue. Description of a case]
Dent Cadmos. 1989 Oct 31;57(16):119-21. Unique Identifier : AIDSLINE MED/90353642
Ficarra G
Human retrovirus-associated malignancy.
Cancer Treat Res. 1989;47:267-84. Unique Identifier : AIDSLINE MED/90329371
McGrath MS; Ng VL
[AIDS: a challenge to health policy and the law]
Schweiz Monatsschr Zahnmed. 1989;99(12):1445-7. Unique Identifier : AIDSLINE MED/90333241
Perret JB
Natural immunity to HIV and its possible relationship to vaccine strategies.
Microbiol Sci. 1988 Aug;5(8):236-41. Unique Identifier : AIDSLINE MED/90329348
Bolognesi DP; Duke University Medical Centre, Department of Surgery, Durham,; North Carolina 27710.
This discussion examines various potential targets of immune attack on human immunodeficiency virus (HIV) as recognized by antibodies obtained experimentally as well as under natural conditions of infection. Various issues related to vaccine strategies are discussed in this light as are limited experimental trials of


AIDS surveillance in the Americas. Cumulative number of cases and deaths as of 31 May 1989.
Epidemiol Bull. 1989;10(1):14. Unique Identifier : AIDSLINE MED/90335012
AIDS surveillance in the Americas. Cases reported by year and cumulative number of cases and deaths by country and subregion, 1986 to 1989.
Epidemiol Bull. 1989;10(2):10. Unique Identifier : AIDSLINE MED/90335015
AIDS surveillance in the Americas. Cumulative number of cases (a)and deaths as of 4 December 1989.
Epidemiol Bull. 1989;10(3):16. Unique Identifier : AIDSLINE MED/90335019
AIDS surveillance in the Americas. Cumulative number of cases and deaths.
Epidemiol Bull. 1988;9(3):16. Unique Identifier : AIDSLINE MED/90335027
AIDS situation in the Americas 1988.
Epidemiol Bull. 1988;9(4):1-11. Unique Identifier : AIDSLINE MED/90335029
Pediatric AIDS, developmental disabilities, and education: a review.
AIDS Educ Prev. 1989 Winter;1(4):291-302. Unique Identifier : AIDSLINE MED/90351733
Klindworth LM; Dokecki PR; Baumeister AA; Kupstas FD; John F. Kennedy Center for Research on Education and Human; Development, Peabody College, Vanderbilt University, Nashville,; TN 37203.
The increasing incidence and prevalence of pediatric HIV infection and associated morbidity suggest that HIV-related neurological impairments and concomitant developmental disabilities are likely to present major societal problems. This article reviews and discusses (a) issues associated with the variable course and m


Radiation therapy eases discomfort of some AIDS patients [news]
Oncology (Huntingt). 1989 Mar;3(3):16. Unique Identifier : AIDSLINE MED/90352033
Detection of HIV DNA in peripheral blood by the polymerase chain reaction: a study of clinical applicability and performance.
AIDS. 1990 May;4(5):389-91. Unique Identifier : AIDSLINE MED/90321484
Young KK; Peter JB; Winters RE; Specialty Laboratories, Inc., Santa Monica, California.
We evaluated the applicability and performance of the polymerase chain reaction (PCR) in a clinical setting in two independent studies. In a study of its applicability, the specificity and sensitivity of PCR for detection of HIV DNA were 100% (225 out of 225 seronegative, low-risk individuals tested negative) and 94%


Heterosexual behaviour of intravenous drug users in Amsterdam: implications for the AIDS epidemic.
AIDS. 1990 May;4(5):449-53. Unique Identifier : AIDSLINE MED/90321493
van den Hoek A; van Haastrecht HJ; Coutinho RA; Department of Public Health and Environment, Amsterdam, The; Netherlands.
In order to assess the potential role of intravenous drug users (IVDUs) in Amsterdam in the heterosexual transmission of HIV, we studied the sexual behaviour of 243 male and female IVDUs with regard to their private ( steady and casual ) and commercial partners. The majority of the study group appear heterosexually


Providing HIV counseling and testing services in methadone maintenance programs.
AIDS. 1990 May;4(5):463-5. Unique Identifier : AIDSLINE MED/90321496
Cartter ML; Petersen LR; Savage RB; Donagher J; Hadler JL; Connecticut Department of Health Services, Hartford.
Counseling about AIDS and optional confidential testing for antibody to HIV-1 have been available in state-supported methadone maintenance programs in Connecticut since 1 January 1987. In the first 2 years of the program, 2118 people received pre-test counseling. Overall, 1521 people agreed to anti-HIV-1-antibody test


HIV infection detected by polymerase chain reaction in an agammaglobulinemic patient [letter]
AIDS. 1990 May;4(5):468-9. Unique Identifier : AIDSLINE MED/90321498
Young KK; Peter JB; Wasserman RL
AIDS-related research in sub-Saharan Africa [letter]
AIDS. 1990 May;4(5):469-70. Unique Identifier : AIDSLINE MED/90321499
Heymann DL; Bres P; Karam M; Biritwum R; Nkowane B; Sow A; Kenya P; Beausoleil EG; Widdus R; Mann JM
Pyomyositis associated with AIDS [letter]
AIDS. 1990 May;4(5):471. Unique Identifier : AIDSLINE MED/90321500
Balachandran T; McLean KA
Statistics from the World Health Organization and the Centers for Disease Control.
AIDS. 1990 May;4(5):473-7. Unique Identifier : AIDSLINE MED/90321501
Antibodies against cryptantigens of platelets in patients with HIV-related thrombocytopenia [letter; comment]
Br J Haematol. 1990 Jun;75(2):298-9. Unique Identifier : AIDSLINE MED/90321881
Muniz-Diaz E; Madoz P; Pastoret C; Arilla M; Lluch A
Risk behaviours for HIV infection among drug users in prison.
BMJ. 1990 May 26;300(6736):1383-4. Unique Identifier : AIDSLINE MED/90321995
Carvell AL; Hart GJ; Academic Department of Genitourinary Medicine, University College; and Middlesex School of Medicine, University College, London.
OBJECTIVE--To study a group of injecting drug users to establish the degree of illicit drug use in prisons, the prevalence of risk behaviours for HIV infection, and the uptake of treatment for drug dependency with drugs within the prison system. DESIGN--Anonymous, self administered, questionnaire. SETTING--Two drug ag


Enterovesical fistula in a patient with cryptosporidiosis and AIDS. CT demonstration.
Clin Imaging. 1990 May;14(2):143-5. Unique Identifier : AIDSLINE MED/90322243
Meyers SA; Kuhlman JE; Fishman EK; Russell H. Morgan Department of Radiology and Radiological; Science, Johns Hopkins Medical Institutions Baltimore, Maryland; 21205.
A case of an enterovesical fistula demonstrated by computed tomography (CT) scan in an AIDS patient with cryptosporidiosis is reported. Other studies including barium enema and endoscopy were unsuccessful in detection of the fistula. The value of CT in both the AIDS patient and the patient with suspected enterovesical


Rapid, simple, and reliable doctor's office test for antibodies to human immunodeficiency virus 1 in serum.
Clin Chem. 1990 Jul;36(7):1312-6. Unique Identifier : AIDSLINE MED/90322663
Dafforn A; Irvine JD; Kurn N; Becker M; Bryning Z; Ullman EF; Syva Co., Palo Alto, CA 94304.
This Unit Test Method assay for detecting anti-human immunodeficiency virus 1 antibody is suitable for nonlaboratory testing and has a sensitivity comparable with that of present enzyme immunoassay methods. The method does not require instrumentation, gives a result in less than 15 min, and incorporates a procedural c


Increased neopterin concentration in saliva of patients with HIV-1 infection.
Clin Chem. 1990 Jul;36(7):1379-80. Unique Identifier : AIDSLINE MED/90322681
Reibnegger G; Fuchs D; Zangerle R; Wachter H; Inst. of Med. Chem. and Biochem., and Dept. of Univ. of; Innsbruck, Austria.
Incidence of HIV antibody-positive eye/cornea donors in hospital versus medical examiner cases.
Cornea. 1990 Jul;9(3):271-2. Unique Identifier : AIDSLINE MED/90322798
Danneffel MB; Sugar A; Michigan Eye-Bank and Transplantation Center, Ann Arbor.
We retrospectively examined Michigan Eye-Bank and Transplantation Center data on all eye/cornea donors in Michigan and Illinois for whom human immunodeficiency virus (HIV) antibody screening results were available. This was done to compare the HIV-antibody positive serology rate in hospital versus medical examiner don


Drug use and unprotected anal intercourse among gay men.
Health Psychol. 1990;9(4):450-65. Unique Identifier : AIDSLINE MED/90322966
Martin JL; Columbia University, School of Public Health, New York, NY 10032.
Conducted a longitudinal study of 604 New York City gay men to examine the link between unprotected insertive and receptive anal intercourse and drug use with sex. Data spanning four 12-month periods from 1980 to 1987 indicated that the link between drug use and high-risk sex diminished as the acquired immunodeficienc


Penicillium marneffei infection in an AIDS patient [letter]
Eur J Clin Microbiol Infect Dis. 1990 May;9(5):370. Unique Identifier : AIDSLINE MED/90323026
Hulshof CM; van Zanten RA; Sluiters JF; van der Ende ME; Samson RS; Zondervan PE; Wagenvoort JH
Differential diagnosis of exophytic lesions in patients with AIDS.
Gen Dent. 1990 May-Jun;38(3):218-20. Unique Identifier : AIDSLINE MED/90323574
Rosenstein DI; Chiodo GT; Eigner TL; Bartley MH
Human T-cell lymphotropic virus type I (HTLV-I) antibodies in pre-diagnostic serum of patients with familial adult T-cell leukemia/lymphoma (ATL).
Hematol Oncol. 1990 May-Jun;8(3):169-76. Unique Identifier : AIDSLINE MED/90323831
Nomura AM; Yanagihara ET; Blattner WA; Ho GY; Inamasu MS; Severson RK; Nakamura JM; Kuakini Medical Center, Honolulu, HI 96817.
In a study of 7498 American men of Japanese ancestry in Hawaii, 26 incident cases of leukemia or non-Hodgkin s lymphoma were identified after a follow-up period of 19 years. Two of the cases, who were brothers, were diagnosed with adult T-cell leukemia/lymphoma (ATL). Both of these


France: AIDS and the workplace [news]
Int Nurs Rev. 1990 May-Jun;37(3):256-7. Unique Identifier : AIDSLINE MED/90324039
Alarming lack of AIDS data for nurses [news]
Int Nurs Rev. 1990 May-Jun;37(3):263. Unique Identifier : AIDSLINE MED/90324040
Tropism of human immunodeficiency virus 1 isolates for H9 cells and U937 cells.
Intervirology. 1990;31(2-4):101-8. Unique Identifier : AIDSLINE MED/90324045
Cory JM; Ohlsson-Wilhelm BM; Rapp F; Department of Microbiology, Pennsylvania State University College; of Medicine, Hershey 17033.
Human immunodeficiency virus 1 (HIV-1) produced in the human T lymphoblastoid H9 cell line infected cells of that line more readily than cells of the human monocytoid U937 line. While both cell lines expressed detectable levels of the CD4 molecule on their surfaces, the H9 and U937 cell lines differed in expression of


Prompting bar patrons with signs to take free condoms.
J Appl Behav Anal. 1990 Summer;23(2):215-7. Unique Identifier : AIDSLINE MED/90324132
Honnen TJ; Kleinke CL; Psychology Department CAS 214, University of Alaska, Anchorage; 99508.
This study was designed to determine whether signs would prompt bar patrons to avail themselves of free condoms. The intervention at three gay bars involved placing a large sign directly above a container of free condoms; the sign gave statistics for the number of people who have died from AIDS in the state and pointe


Isolation of highly purified human blood monocytes for in vitro HIV-1 infection studies of monocyte/macrophages.
J Immunol Methods. 1990 Jul 3;130(2):283-5. Unique Identifier : AIDSLINE MED/90324636
Hassan NF; Cutilli JR; Douglas SD; Division of Infectious Diseases and Immunology, Joseph Stokes,; Jr. Research Institute, Children's Hospital of Philadelphia,; University of Pennsylvania Medical School 19104.
Patterns of HIV-1 and HTLV-I/II in intravenous drug abusers from the middle atlantic and central regions of the USA.
J Infect Dis. 1990 Aug;162(2):347-52. Unique Identifier : AIDSLINE MED/90324644
Lee HH; Weiss SH; Brown LS; Mildvan D; Shorty V; Saravolatz L; Chu A; Ginzburg HM; Markowitz N; Des Jarlais DC; et al; Abbott Laboratories, North Chicago, IL 60064.
Seroprevalence of human immunodeficiency virus type 1 (HIV-1) and human T lymphotropic virus types I and II (HTLV-I/II) was determined among 1160 intravenous (iv) drug abusers from five drug treatment or medical centers (Manhattan, Brooklyn, New Jersey, Detroit, and New Orleans). HIV-1 infection ranged from 5% in New


When the doctor has AIDS.
J Infect Dis. 1990 Aug;162(2):534-7. Unique Identifier : AIDSLINE MED/90324674
Gramelspacher GP; Miles SH; Cassel CK; Department of Medicine, Indiana University School of Medicine,; Indianapolis 46202.
Contrasting prevalence of delta hepatitis markers in parenteral drug abusers with and without AIDS.
J Infect Dis. 1990 Aug;162(2):538-41. Unique Identifier : AIDSLINE MED/90324675
Kreek MJ; Des Jarlais DC; Trepo CL; Novick DM; Abdul-Quader A; Raghunath J; Rockefeller University, New York, NY 10021.
Parenteral drug abusers are the second largest group at risk for developing AIDS (25% of US cases) and a major risk group for infection with both hepatitis B virus (HBV) and the HBV-dependent RNA hepatitis delta virus (HDV). This study was conducted to determine the prevalence in 1984-1985 and relationships of HDV and


Concordance of polymerase chain reaction with human immunodeficiency virus antibody detection.
J Infect Dis. 1990 Aug;162(2):542-5. Unique Identifier : AIDSLINE MED/90324676
Horsburgh CR Jr; Ou CY; Jason J; Holmberg SD; Lifson AR; Moore JL; Ward JW; Seage GR; Mayer KH; Evatt BL; et al; Division of HIV/AIDS, Centers for Disease Control, Atlanta,; Georgia 30333.
To evaluate the correlation of detection of human immunodeficiency virus (HIV) by polymerase chain reaction (PCR) with detection of HIV antibody, 271 simultaneous serum and peripheral blood mononuclear cell samples were examined from 242 persons whose activities placed them at increased risk for HIV infection: 142 fro


Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine.
J Med Chem. 1990 Aug;33(8):2188-92. Unique Identifier : AIDSLINE MED/90325212
Chu CK; Bhadti VS; Doshi KJ; Etse JT; Gallo JM; Boudinot FD; Schinazi RF; Department of Medicinal Chemistry and Pharmacognosy, College of; Pharmacy, University of Georgia, Athens 30602.
A significant number of patients with AIDS and AIDS-related complex develop neurological complications. Therefore, it is critical that anti-HIV agents penetrate the blood-brain barrier and suppress viral replication in the brain. In an effort to increase the brain delivery of anti-HIV nucleosides, in vitro and in vivo


The Sixth International AIDS Conference: a week of hope and protest [news]
J Natl Cancer Inst. 1990 Aug 1;82(15):1240-2. Unique Identifier : AIDSLINE MED/90325273
Mahaney FX Jr
Science ponders whether HIV acts alone or has another microbe's aid [news]
JAMA. 1990 Aug 8;264(6):665-6. Unique Identifier : AIDSLINE MED/90325443
Goldsmith MF
Did HIV and HTLV originate in Africa? [letter] [see comments]
JAMA. 1990 Aug 8;264(6):691-2. Unique Identifier : AIDSLINE MED/90325450
Tabor E; Gerety RJ; Cairns J; Bayley AC
Undergraduate medical education.
JAMA. 1990 Aug 15;264(7):801-9. Unique Identifier : AIDSLINE MED/90325472
Jonas HS; Etzel SI; Barzansky B; American Medical Association, Division of Undergraduate Medical; Education.
The number of applicants to US medical schools, which declined steadily between 1985 and 1988, increased slightly for the class entering in 1989. The profile of entering students showed a small decline from last year in the percentage of students with grade point averages categorized as A (3.5 or above on a 4-point sc


Trace elements in drug addicts.
Klin Wochenschr. 1990 May 17;68(10):507-11. Unique Identifier : AIDSLINE MED/90325652
Ruiz Martinez M; Gil Extremera B; Maldonado Martin A; Cantero-Hinojosa J; Moreno-Abadia V; Centro Provincial de Drogodependencias (Provincial Center for; Drug Addiction), Granada, Espana.
We studied trace elements (zinc, copper, magnesium, iron, and lithium) by atomic absorption spectrophotometry in the plasma and erythrocytes of 120 subjects: 20 healthy controls and 100 parenteral drug addicts (69 heroin and 31 heroin + other drugs). Plasma Zn and intraerythrocytic Zn and Fe were decreased, whereas pl


[Adolescents and AIDS]
Krankenpfl Soins Infirm. 1990 Jul;83(7):62-7. Unique Identifier : AIDSLINE MED/90325690
Chetelat RM
The pattern of HIV infection in a southern state and city: a model for the outpatient clinic.
J Tenn Med Assoc. 1990 Jul;83(7):339-43. Unique Identifier : AIDSLINE MED/90325729
Palte SB; Lancaster DJ; Miller ST; Morrison RE; Bobo L; Department of Medicine, University of Tennessee Center for the; Health Sciences, Memphis.
Adolescents' knowledge of AIDS: a pilot study in northeast Tennessee.
J Tenn Med Assoc. 1990 Jul;83(7):344-6. Unique Identifier : AIDSLINE MED/90325730
Granger J; West R; Naramore H; Snow D; Clark H; Department of Psychiatry and Behavioral Sciences, James H.; Quillen College of Medicine, Johnson City, TN 37601.
AIDS surveillance in Tennessee: a report of trends, 1982-1989.
J Tenn Med Assoc. 1990 Jul;83(7):354-5. Unique Identifier : AIDSLINE MED/90325735
Ellis BH Jr; Tennessee Department of Health and Environment, Nashville.
AIDS: the legal ramifications of nonconsensual, mandatory testing [published erratum appears in J Tenn Med Assoc 1990 Aug;83(8):426] [see comments]
J Tenn Med Assoc. 1990 Jul;83(7):356-7. Unique Identifier : AIDSLINE MED/90325736
Overlock ME
Responsibility in government [editorial] [see comments]
J Tenn Med Assoc. 1990 Jul;83(7):362-3. Unique Identifier : AIDSLINE MED/90325738
Thomison JB
Global coordination of national public health strategies.
Law Med Health Care. 1990 Spring-Summer;18(1-2):20-8. Unique Identifier : AIDSLINE MED/90325798
Mann J; Dam M; Kay K
Screening for HIV infection and public health policy.
Law Med Health Care. 1990 Spring-Summer;18(1-2):29-32. Unique Identifier : AIDSLINE MED/90325799
Fineberg HV
AIDS-related legislation in the context of the third AIDS pandemic.
Law Med Health Care. 1990 Spring-Summer;18(1-2):41-7. Unique Identifier : AIDSLINE MED/90325801
Jayasuriya DC
Bioethics, '89: can democracy cope?
Law Med Health Care. 1990 Spring-Summer;18(1-2):5-10. Unique Identifier : AIDSLINE MED/90325803
Kirby M
[HIV detection with polymerase chain reaction (news)]
Med Monatsschr Pharm. 1990 Jun;13(6):194-5. Unique Identifier : AIDSLINE MED/90326015
Koopmann I
[Pentamidine in the treatment of pneumocystosis]
Med Klin. 1990 Apr;85 Suppl 2:229-30. Unique Identifier : AIDSLINE MED/90326028
Dietrich M; Klinische Abteilung, Bernhard-Nocht-Instituts fur Tropenmedizin,; Hamburg.
[Pentamidine inhalation for therapy and prophylaxis of Pneumocystis carinii pneumonia. Results of the working discussion of the Section for Antiparasite Chemotherapy of the Paul Ehrlich Society]
Med Klin. 1990 Apr;85 Suppl 2:229-90. Unique Identifier : AIDSLINE MED/90326029
[Pharmacologic studies with pentamidine aerosol in HIV patients]
Med Klin. 1990 Apr;85 Suppl 2:248-50, 291. Unique Identifier : AIDSLINE MED/90326033
Vohringer HF; Arasteh K; Hardtmann E; Hornscheidt M; Auguste-Viktoria-Krankenhaus, Akademisches Lehrkrankenhaus der; Freien Universitat Berlin.
1. After multiple intravenous and inhaled application of pentamidine a steady state of plasma concentrations and of urinary excretion amounts is suggested to occur between the sixth and eighth day of the treatment. An elimination half life of at mean four days and a great volume of distribution of greater than 100 l/k


[Comparison of the effect of 2 therapy concepts in the treatment of Pneumocystis carinii pneumonia. Cotrimoxazole for 21 days versus sequential therapy with cotrimoxazole followed by pentamidine inhalation]
Med Klin. 1990 Apr;85 Suppl 2:264-7. Unique Identifier : AIDSLINE MED/90326038
Helm EB; Staszewski S; Arasteh K; Jacobi V; Mulert R; Wegner R; Ottmann O; Brodt HR; L'age M; Stille W; Zentrum der Inneren Medizin, Universitatsklinik Frankfurt.
Standard therapy of pneumocystis carinii pneumonia with cotrimoxazole and intravenous pentamidine second line therapy both have a response rate of 75 to 90%. As severe side effects, myelotoxicity and skin reaction have been observed which may occur from treatment day 7 on. In order to prevent such side effects as well


[Prospective study of primary and secondary prevention of Pneumocystis carinii pneumonia with pentamidine aerosol]
Med Klin. 1990 Apr;85 Suppl 2:271-5. Unique Identifier : AIDSLINE MED/90326040
Staszewski S; Trinder S; Gottstein A; Odewald J; Rehmet S; Brodt R; Jacobi V; Muller R; Muller H; Helm EB; et al; Zentrum der Inneren Medizin, Infektiologie, Klinikum der; Johann-Wolfgang-Goethe-Universitat, Frankturt a. M.
In an open prospective study in the AIDS Outpatient Department of the Frankfurt University Clinic the efficacy of pentamidine aerosol at a dosage of 200 mg every 14 days in the primary and secondary prophylaxis of pneumocystis carinii pneumonia was tested. The incidence of pneumocystis carinii pneumonia was reduced by


HIV requires multiple gp120 molecules for CD4-mediated infection.
Nature. 1990 Jul 19;346(6281):277-9. Unique Identifier : AIDSLINE MED/90326160
Layne SP; Merges MJ; Dembo M; Spouge JL; Nara PL; Theoretical Division, Los Alamos National Laboratory, New Mexico; 87545.
Binding of glycoprotein gp120 to the T cell-surface receptor CD4 is a crucial step in CD4-dependent infection of a target cell by the human immunodeficiency virus (HIV). Blocking some or all gp120 molecules on the viral surface should therefore inhibit infection. Consequently, competitive receptor inhibitors, such as


[The neurological and neuropsychological status of HIV-seropositive persons without symptoms]
Ned Tijdschr Geneeskd. 1990 Jul 7;134(27):1292-3. Unique Identifier : AIDSLINE MED/90326199
Portegies P; Academisch Medisch Centrum, afd. Neurologie, Amsterdam.
[The status of autopsies; the analysis of clinical pathology]
Ned Tijdschr Geneeskd. 1990 Jul 14;134(28):1340-3. Unique Identifier : AIDSLINE MED/90326210
Bosman FT; Rijksuniversiteit Limburg, Faculteit der Geneeskunde, Vakgroep; Pathologie, Maastricht.
[AIDS autopsies, a matter of decency]
Ned Tijdschr Geneeskd. 1990 Jul 14;134(28):1343-5. Unique Identifier : AIDSLINE MED/90326211
van den Tweel JG; Academisch Medisch Centrum, afd. Pathologische Anatomie,; Amsterdam.
[HIV prevalence among heterosexual subjects with multiple partners in Amsterdam]
Ned Tijdschr Geneeskd. 1990 Jul 14;134(28):1361-4. Unique Identifier : AIDSLINE MED/90326216
van der Linden MM; van der Velde FW; Hooykaas C; van Doornum GJ; Coutinho RA; Gemeentelijke Geneeskundige en Gezondheidsdienst, sector; Volksgezondheid en Milieu, Amsterdam.
To study the prevalence of HIV-infection among heterosexuals with multiple partners, participants were recruited from a STD clinic in Amsterdam. In 1988, 785 visitors met the selection criteria, of whom 361 (46%) finally participated. An HIV prevalence of 2/361 (0.6%) was found among participants. To test representati


[Symptoms in suspected and early stages of HIV infections in 2 Amsterdam family practices]
Ned Tijdschr Geneeskd. 1990 Jul 21;134(29):1405-9. Unique Identifier : AIDSLINE MED/90326226
Meijman FJ; Universiteit van Amsterdam, afd. Studentenartsen/Huisartspraktijk; Oude Turfmark.
The symptoms and courses of (suspected) HIV infections before referral were investigated in a retrospective patient chart survey in two general practices with a total of 8500 patients. The patients comprised 47 men and three women. In 38 men and one woman, symptoms suggestive of HIV infection were observed while the r


International AIDS conference [news]
N Z Med J. 1990 Jul 25;103(894):358. Unique Identifier : AIDSLINE MED/90326323
A replication-deficient HIV-1 DNA used for quantitation of the polymerase chain reaction (PCR).
Nucleic Acids Res. 1990 Jul 11;18(13):4029-30. Unique Identifier : AIDSLINE MED/90326564
Hart C; Chang SY; Kwok S; Sninsky J; Ou CY; Schochetman G; Centers for Disease Control, Atlanta, GA 30333.
AIDS: protecting both surgeon and patient [editorial]
Orthopedics. 1990 Jul;13(7):705. Unique Identifier : AIDSLINE MED/90326626
D'Ambrosia R
[Prevention of infection at the autopsy table: use of so-called impenetrable protective gloves]
Pathologe. 1990 May;11(3):192-4. Unique Identifier : AIDSLINE MED/90326650
Huckenbeck W; de Jonge JP; Institut fur Rechtsmedizin, Heinrich-Heine-Universitat; Dusseldorf.
[Diarrhea cause by parasites]
Schweiz Rundsch Med Prax. 1990 Jul 17;79(29-30):877-81. Unique Identifier : AIDSLINE MED/90326938
Marbet UA; Departement fur Innere Medizin, Regionalspital Herisau.
Parasites, once an exclusively tropical problem, are rare causes of diarrhea in our countries. Increasing tourism and immune deficiencies due to treatment or to Aids lead to an increase of intestinal parasites in western countries. The most frequent pathogenic parasites are Giardia lamblia and Entamoeba histolytica bu


Severe phenytoin intoxication as a result of altered protein binding in AIDS.
DICP. 1990 Jul-Aug;24(7-8):698-700. Unique Identifier : AIDSLINE MED/90327797
Toler SM; Wilkerson MA; Porter WH; Smith AJ; Chandler MH; College of Pharmacy, University of Kentucky, Lexington.
Alterations in plasma protein binding may alter patient response to pharmaceutical agents because only free drug is considered to be pharmacologically active. Such alterations appear to be more significant with highly bound agents such as phenytoin. Traditionally, most drug assays monitor total drug concentrations and


ATLL complicated by strongyloidiasis and isosporiasis: case report.
Va Med Q. 1990 Summer;117(7):311-6. Unique Identifier : AIDSLINE MED/90327866
Massey AC; Weinstein DL; Petri WA; Williams ME; Hess CE; Department of Internal Medicine, University of Virginia,; Charlottesville 22908.
In summary, we present this as the first reported case of both isosporiasis and strongyloidiasis complicating HTLV-I-associated ATLL. Prompt diagnosis and treatment of these parasites in the immunocompromised host are necessary to prevent severe wasting and dehydration. Th


A case of Pneumocystis carinii in pleural fluid with cytologic, histologic and ultrastructural documentation.
Acta Cytol. 1990 Jul-Aug;34(4):486-90. Unique Identifier : AIDSLINE MED/90327939
Balachandran I; Jones DB; Humphrey DM; Department of Pathology, State University of New York, Health; Science Center, Syracuse 13210.
Pneumocystis carinii involvement of the pleural cavity in a patient with the acquired immune deficiency syndrome was documented by cytologic as well as scanning and transmission electron microscopic study of pleural fluids. Histologic examination of the pleura and the subpleural lung revealed vasculitis and infarctlik


Vulvar ulcer of unknown etiology in a human immunodeficiency virus-infected woman: response to treatment with zidovudine [see comments]
Am J Obstet Gynecol. 1990 Jul;163(1 Pt 1):116-8. Unique Identifier : AIDSLINE MED/90328179
Covino JM; McCormack WM; Department of Medicine, State University of New York Health; Science Center, Brooklyn 11203.
We report a woman who presented with an intractable vulvar ulcer of unknown etiology. Human immunodeficiency virus antibodies and a depressed CD4 lymphocyte count were the only remarkable findings. There was no evidence of syphilis, chancroid, or herpes simplex virus infection. The ulcer healed in association with tre


Photopheresis and human immunodeficiency virus (HIV) infection: the Annals views preliminary reports [editorial; comment]
Ann Intern Med. 1990 Aug 15;113(4):263-4. Unique Identifier : AIDSLINE MED/90328554
Abrutyn E
Compliance with zidovudine therapy [letter]
Ann Intern Med. 1990 Aug 15;113(4):332-3. Unique Identifier : AIDSLINE MED/90328569
Reichman LB
Nationwide survey of HTLV-I-associated myelopathy in Japan: association with blood transfusion.
Ann Neurol. 1990 Jul;28(1):50-6. Unique Identifier : AIDSLINE MED/90328724
Osame M; Janssen R; Kubota H; Nishitani H; Igata A; Nagataki S; Mori M; Goto I; Shimabukuro H; Khabbaz R; et al; Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima University, Japan.
To study the epidemiology of human T-cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan , we conducted two nationwide surveys between October 1986 and March 1989. A total of 710 patients with HAM (definite HAM, 589; probable


Perisinusoidal cell hypertrophy in a patient with acquired immunodeficiency syndrome.
Arch Pathol Lab Med. 1990 Aug;114(8):876-9. Unique Identifier : AIDSLINE MED/90328813
Kossaifi T; Dupon M; Le Bail B; Lacut Y; Balabaud C; Bioulac-Sage P; Laboratoire des Interactions Cellulaires, Universite de Bordeaux; II, France.
A 33-year-old heterosexual white man underwent a liver biopsy for determination of mild elevation of aminotransferase levels (aspartate aminotransferase, two times; alanine aminotransferase, three times). The patient had acquired immunodeficiency syndrome (stage IVC2) with tuberculosis of the lymph nodes. Antibody to


Progressive resistance exercise: effect on muscle function and anthropometry of a select AIDS population.
Arch Phys Med Rehabil. 1990 Aug;71(9):644-8. Unique Identifier : AIDSLINE MED/90328823
Spence DW; Galantino ML; Mossberg KA; Zimmerman SO; Department of Human Performance and Health Sciences, Rice; University, Houston, TX 77251-1892.
Substantial body tissue wasting has been reported in acquired immune deficiency syndrome (AIDS) patients. The purpose of this investigation was to determine if progressive resistance exercise (PRE) would improve muscle function and increase body dimensions and mass in AIDS patients. The subjects were 24 male outpatien


AAOHN and the development of a bloodborne pathogens standard.
AAOHN J. 1990 Aug;38(8):388-9. Unique Identifier : AIDSLINE MED/90329091
Knowledge and attitudes of Texas dentists concerning AIDS.
Am J Dent. 1990 Feb;3(1):5-8. Unique Identifier : AIDSLINE MED/90329202
Dove SB; Cottone JA
A total of 1,200 practicing Texas dentists were surveyed concerning AIDS knowledge, attitudes and behaviors. The results were analyzed and an analysis of variance indicated an inverse relationship between city population and avoidance behavior towards AIDS by dentists. Additionally, dentists in practice over 10 years


Comparison of the attitudes of hospital dentists and dental students in Glasgow, UK and Los Angeles, USA towards treatment of AIDS and hepatitis B patients.
Am J Dent. 1990 Feb;3(1):9-14. Unique Identifier : AIDSLINE MED/90329203
Samaranayake LP; Figueiredo HM; Rowland CA; Aitchison K
A transcultural comparison of the attitudes of hospital dental practitioners and final year dental students in Glasgow, Scotland and Los Angeles, USA was made to assess their attitudes towards treatment of AIDS and hepatitis B patients. Almost all of the respondents were aware of the facts related to spread of AIDS vi


Indications for zidovudine expanded to include use in children [news]
Clin Pharm. 1990 Jul;9(7):502. Unique Identifier : AIDSLINE MED/90329741
Occupational exposure to aerosolized pentamidine.
Chest. 1990 Aug;98(2):386-8. Unique Identifier : AIDSLINE MED/90329837
Montgomery AB; Corkery KJ; Brunette ER; Leoung GS; Waskin H; Debs RJ; Medical Service, San Francisco General Hospital Medical Center.
Occupational exposure to aerosolized pentamidine has raised questions regarding transmission of tuberculosis and the effect of the drug itself. To estimate the exposure of a health care worker, we measured the ambient concentration of aerosolized pentamidine in field conditions in 36 m3 unventilated treatment room. Th


Bronchoalveolar lavage in sarcoidosis and HIV infection [letter; comment]
Chest. 1990 Aug;98(2):517-8. Unique Identifier : AIDSLINE MED/90329882
The epidemiology of human immunodeficiency virus infection and acquired immunodeficiency syndrome in the United States.
Ear Nose Throat J. 1990 Jun;69(6):394-400. Unique Identifier : AIDSLINE MED/90330005
Hamburg MA; National Institute of Allergy and Infectious Diseases, National; Institutes of Health, Bethesda, MD.
As of October 1989, there were more than 112,000 documented cases of AIDS and more than 1 million Americans were thought to be infected with HIV. Three primary routes of HIV transmission have been defined: sexual contact, parenteral exposure, and perinatal transmission. Epidemiologic surveillance studies provide impor


Patient care issues in the acquired immunodeficiency syndrome.
Ear Nose Throat J. 1990 Jun;69(6):432-5. Unique Identifier : AIDSLINE MED/90330010
Lucente FE; Department of Otolaryngology, New York Medical College-New York; Eye and Ear Infirmary.
The AIDS epidemic challenges practitioners to examine all aspects of the patient-physician relationship, including forms of interpersonal communication, the scope of physician responsibility, and the influence of the patient care experience on the physician s own psychological well-being. The burden of dealing with th


[AIDS--personal responsibility and social problem]
Dermatol Monatsschr. 1990;176(4):215-8. Unique Identifier : AIDSLINE MED/90330046
Sonnichsen N; Klinik und Poliklinik fur Hautkrankheiten, Bereichs Medizin; (Charite), Humboldt-Universitat zu Berlin.
[Pneumonia: special course in AIDS. Pneumocystis carinii pneumonia--inhalation therapy]
Fortschr Med. 1990 Jun 10;108(17):72-3. Unique Identifier : AIDSLINE MED/90330241
Vollmer H
Dynamics of HIV infection and AIDS in central African cities.
Int J Epidemiol. 1990 Jun;19(2):417-28. Unique Identifier : AIDSLINE MED/90330376
Auvert B; Moore M; Bertrand WE; Beauchet A; Aegerter P; Lusamba D; Diong KT; Klinowski J; INSERM U88, 91 Boulevard de l'Hopital, Paris, France.
A detailed stochastic model of HIV infection and AIDS for large cities in central Africa is described, which reproduces past events in Kinshasa, Zaire and projects rapid future spread of the disease, consistent with recent findings for Nairobi, Keny


Factors associated with AIDS and AIDS-like syndrome among homosexual and bisexual men in Minas Gerais, Brazil.
Int J Epidemiol. 1990 Jun;19(2):429-34. Unique Identifier : AIDSLINE MED/90330377
de Lima e Costa MF; Oliveira MR; Oliveira EI; Paulino UH; Greco DB; Chiari CA; Guimaraes MD; Proietti FA; Antunes CM; Munoz A; Universidade Federal de Minas Gerais, Brazil.
A case-control study to determine factors associated with AIDS and AIDS-like syndrome among homosexual/bisexual men was conducted in the State of Minas Gerais ( Brazil ). Eighty-three per cent (45 patients) of all AIDS/AIDS-like syndrome cases in homosexual/bisexual men reported in M


International experts study AIDS and human rights [news]
Int Nurs Rev. 1990 Mar-Apr;37(2):224. Unique Identifier : AIDSLINE MED/90330407
ICN: African NNAs prepare for AIDS campaign [news]
Int Nurs Rev. 1990 Mar-Apr;37(2):224. Unique Identifier : AIDSLINE MED/90330408
WHO: Executive Board deals with priority areas [news]
Int Nurs Rev. 1990 Mar-Apr;37(2):225. Unique Identifier : AIDSLINE MED/90330409
WHO: all-out fight starts against drug epidemic [news]
Int Nurs Rev. 1990 Mar-Apr;37(2):225-6. Unique Identifier : AIDSLINE MED/90330410
WHO: World AIDS Day to focus on women [news]
Int Nurs Rev. 1990 Mar-Apr;37(2):226. Unique Identifier : AIDSLINE MED/90330411
WHO: getting teachers involved in AIDS prevention [news]
Int Nurs Rev. 1990 Mar-Apr;37(2):227. Unique Identifier : AIDSLINE MED/90330412
WHO: emergency plan to fight AIDS in Romania [news]
Int Nurs Rev. 1990 Mar-Apr;37(2):230-1. Unique Identifier : AIDSLINE MED/90330413
Confidentiality and HIV status: the nurse's right to know.
Home Healthc Nurse. 1990 May-Jun;8(3):6-8. Unique Identifier : AIDSLINE MED/90330470
Brent NJ
Partition coefficients and capacity factors of some nucleoside analogues.
J Chromatogr. 1990 May 11;506:119-31. Unique Identifier : AIDSLINE MED/90330708
Cheung AP; Kenney D; Life Sciences Division, SRI International, Menlo Park, CA 94025.
The AIDS epidemic has brought into focus the development of antiviral agents, of which nucleoside analogues are an important class. The single most important physico-chemical property of a chemotherapeutic agent is its hydrophobicity. This paper reports the hydrophobicity, determined as log partition coefficient (P) b


Buspirone in drug users with AIDS or AIDS-related complex.
J Clin Psychopharmacol. 1990 Jun;10(3 Suppl):111S-115S. Unique Identifier : AIDSLINE MED/90330759
Batki SL; Department of Psychiatry, University of California, San Francisco; School of Medicine.
Anxiety is a prominent feature of human immunodeficiency virus (HIV)-related psychiatric disorders. Psychiatric disorders are associated with poor drug abuse treatment outcome in both healthy and HIV-infected drug users. While it is important to treat anxiety, the use of traditional antianxiety agents such as benzodia


Adverse exposures and universal precautions practices among a group of highly exposed health professionals.
Infect Control Hosp Epidemiol. 1990 Jul;11(7):351-6. Unique Identifier : AIDSLINE MED/90330824
Willy ME; Dhillon GL; Loewen NL; Wesley RA; Henderson DK; Hospital Epidemiology Service, National Institutes of Health,; Bethesda, MD 20892.
An anonymous national survey of a representative population of healthcare workers who were thought likely to have frequent and intensive exposures to blood and other body fluids (certified nurse-midwives [CNMs]), was conducted to assess the type and frequency of self-reported occupational exposures to blood and body f


Nasopharyngeal cyst simulating Kaposi's sarcoma in an HIV-infected patient.
J Laryngol Otol. 1990 Jun;104(6):498-500. Unique Identifier : AIDSLINE MED/90330913
Harrison HC; Tindall B; McCarthy SW; Cooper DA; Ear, Nose and Throat Department, Sydney Hospital, Australia.
A case of nasopharyngeal cyst in a 30-year-old male homosexual intravenous drug user infected with the human immunodeficiency virus (HIV) is presented. The similarity in clinical presentation of nasopharyngeal cyst and Kaposi s sarcoma is discussed.


[A clinical and immunological study on non-Hodgkin's malignant lymphoma in nasosinus region]
Nippon Jibiinkoka Gakkai Kaiho. 1990 Apr;93(4):554-65. Unique Identifier : AIDSLINE MED/90331076
Uchizono A; Fukuda K; Itoh K; Ushikai M; Ohyama M; Department of Otolaryngology, Kagoshima University, School of; Medicine.
Twenty-eight cases of non-Hodgkin s lymphoma in nasosinus region were studied for tumor-surface marker phenotype, anti-HTLV-I antibody titer and histopathologic correlation with clinical features. The incidence of these cases was 25% of all lymphomas in head and neck region from 19


[Three cases of pulmonary atypical mycobacteriosis associated with lung cancer and adult T-cell leukemia]
Kekkaku. 1990 Apr;65(4):285-92. Unique Identifier : AIDSLINE MED/90331376
Komori K; Senju R; Kadota J; Fukushima K; Hirota M; Hara K; Hashimoto A; Hiratani K; Yatsugi M; Miyazaki T; Second Department of Internal Medicine, Nagasaki University; School of Medicine, Japan.
Three cases of pulmonary atypical mycobacteriosis (AM) were reported. Two cases were associated with lung cancer in which the diagnosis of malignancy was difficult and delayed by the coexistence of AM. The third was a case of adult T-cell leukemia (ATL) which manifested during the course of AM. In case 1 (73 years, ma


[Mandatory AIDS testing: for or against?]
Krankenpfl Soins Infirm. 1990 Jun;83(6):28-9. Unique Identifier : AIDSLINE MED/90331442
Faust PY; Emery JC; Marchand J; Richard J
[1st European Conference for caregivers, Copenhagen. The nurses' fear of AIDS]
Krankenpfl Soins Infirm. 1990 Jun;83(6):71. Unique Identifier : AIDSLINE MED/90331449
Heer S
[Acquired immunodeficiency syndrome: a descriptive study and analysis of survival in 73 cases]
Med Clin (Barc). 1990 Mar 24;94(11):401-5. Unique Identifier : AIDSLINE MED/90331544
Miralles R; Garces JM; Gallen M; Gutierrez-Cebollada J; Torne J; Lopez-Colomes JL; Yazbeck H; Prats F; Servicio de Medicina Interna, Hospital del Mar. Universidad; Autonoma de Barcelona.
The clinical features and prognostic factors influencing survival in 73 patients diagnosed of acquired immunodeficiency syndrome (AIDS) from June 1984 to November 1988 were evaluated. Mean age was 32 years. The predominant risk group were drug abusers (67%). The most common opportunistic infections were extrapulmonary


[Prevalence of type 1 human immunodeficiency virus (HIV) infection in African patients residing in Catalonia]
Med Clin (Barc). 1990 Mar 24;94(11):414-6. Unique Identifier : AIDSLINE MED/90331546
Savall R; Valls F; Fernandez JL; Balanzo X; Seccion de Dermatologia, Hospital Sant Jaume i Santa Magdalena,; Mataro, Barcelona.
278 black patients from West Africa, living in Maresme, a coastal area north of Barcelona were studied in order to determine the prevalence of HIV-1 infection. During the first period (1984-86), 102 patients were studied, 3 of them were positive for HIV-2, but none was positive for HIV-1. In the second period (1987-89


[The acquired immunodeficiency syndrome after 10 years (editorial)]
Med Clin (Barc). 1990 Mar 24;94(11):420-2. Unique Identifier : AIDSLINE MED/90331548
Gatell JM; Miro JM; Servicio de Infecciones, Hospital Clinic i Provincial,; Barcelona.
[Ocular toxoplasmosis in patients with acquired immunodeficiency syndrome]
Med Clin (Barc). 1990 Mar 24;94(11):423-5. Unique Identifier : AIDSLINE MED/90331549
Santin M; Podzamczer D; Bolao F; Prat J; Rufi G; Ariza J; Lillo J; Departamento de Medicina, Hospital de Bellvitge-Princeps; d'Espanya.
Ocular toxoplasmosis is an uncommonly reported complication in patients with acquired immunodeficiency syndrome. Three patients with human immunodeficiency virus (HIV) infection and ocular toxoplasmosis are reported. In two of them, cerebral toxoplasmosis was associated. Ocular involvement presented as exudative chori


[HIV-1 and HIV-2 coinfection or cross reaction? (letter)]
Med Clin (Barc). 1990 Mar 24;94(11):437-8. Unique Identifier : AIDSLINE MED/90331551
Calderon E; Corzo JE; Pineda JA; Leal M
AIDS and tuberculosis [news]
Lepr Rev. 1990 Jun;61(2):197-8. Unique Identifier : AIDSLINE MED/90331635
Recombinant-based competitive anti-HIV assay: solution of some operating problems.
Med Lab Sci. 1990 Jan;47(1):52-4. Unique Identifier : AIDSLINE MED/90331672
Challis P; Barbara JA; North London Blood Transfusion Centre, Colindale, England, UK.
Using the Wellcozyme anti-HIV recombinant assay at 47 degrees, a strongly reactive result with an anti-HIV positive serum sample could not be reproduced when the corresponding plasma sample was used. Dilution in anti-HIV negative serum or kaolin treatment of the plasma specimen produced the clear reactivity seen with


Protein and energy substrate metabolism in AIDS patients.
Metabolism. 1990 Aug;39(8):876-81. Unique Identifier : AIDSLINE MED/90331768
Stein TP; Nutinsky C; Condoluci D; Schluter MD; Leskiw MJ; Department of Surgery, University of Medicine and Dentistry of; New Jersey, School of Osteopathic Medicine, Camden 08103.
The objective of this study was to investigate protein and glucose metabolism in ambulatory, asymptomatic acquired immunodeficiency syndrome (AIDS) patients. Nine asymptomatic AIDS patients were compared against 13 controls. We measured whole-body protein synthesis (PSRM), breakdown (PBRM), and the fractional fibrinog


Australian standards for privacy and confidentiality of health records in research: implications of the Commonwealth Privacy Act.
Med J Aust. 1990 Jun 18;152(12):664-9. Unique Identifier : AIDSLINE MED/90331810
Berglund CA; School of Community Medicine, University of New South Wales,; Kensington.
The current Australian legal, administrative and professional standards for individual rights to confidentiality and privacy of health records are examined and guidance is offered for the use of personal information in research. The implications of recently introduced privacy legislation for the conduct of research in


The injecting and sexual behaviour of intravenous drug users in Sydney [letter; comment] [see comments]
Med J Aust. 1990 Jun 18;152(12):672. Unique Identifier : AIDSLINE MED/90331813
Dinnen A
[The value of fiberoptic bronchoscopy in diagnosis of HIV associated infections]
Med Klin. 1990 Jun 15;85(6):361-5. Unique Identifier : AIDSLINE MED/90331880
Fischer B; Elmer M; Ramadori G; Lorenz J; III. Medizinische Klinik und Poliklinik, Universitatskliniken; Mainz.
32 patients with HIV infection presenting with fever or abnormal chest radiograph or both were investigated at the University Hospital of Mainz (FRG). Fiberoptic bronchoscopy with bronchoalveolar lavage and transbronchial biopsy was undertaken in each patient, additionally other methods were used for isolating pathoge


HTLV-I-associated myelopathy [letter]
N Engl J Med. 1990 Aug 23;323(8):552. Unique Identifier : AIDSLINE MED/90331974
Engel WK; Hanna CJ; Misra AK
AIDS in India: disaster looms for Bombay [news]
Nature. 1990 Aug 9;346(6284):499. Unique Identifier : AIDSLINE MED/90332017
Jayaraman KS
AIDS research: mice or men? [news]
Nature. 1990 Aug 9;346(6284):499. Unique Identifier : AIDSLINE MED/90332018
Schaefer E
Beginning of AIDS [letter; comment]
Nature. 1990 Aug 9;346(6284):505. Unique Identifier : AIDSLINE MED/90332023
Primary T-cell lymphoma with myelopathy associated with HTLV-1.
Neurosurgery. 1990 Jul;27(1):148-51. Unique Identifier : AIDSLINE MED/90332112
Inoue M; Kawaguchi T; Yokoyama H; Shimada M; Department of Neurosurgery, Nagasaki Rosai Hospital, Japan.
The case of a patient who had myelopathy associated with human T-cell lymphotropic virus Type 1 (HTLV-1) for 10 years and developed a T-cell lymphoma in the cerebellum is reported. The relationship between myelopathy associated with HTLV-1 and primary T-cell lymphoma is discussed.


Caring for persons with AIDS: student reactions.
Nurse Educ. 1990 Jul-Aug;15(4):16-20. Unique Identifier : AIDSLINE MED/90332198
Klisch ML
Nursing students must be prepared to care for persons with AIDS in all health care settings. The author examines common reactions of nursing students to caring for persons with AIDS and proposes creative strategies for nursing faculty to facilitate adaptation of students to this challenge.


HTLV increases HIV risk.
Nurs Times. 1990 Jun 27-Jul 3;86(26):10. Unique Identifier : AIDSLINE MED/90332475
Page JB; Lai S; Chitwood DD
No overall gain after AIDS therapy.
Nurs Times. 1990 Jul 4-10;86(27):10. Unique Identifier : AIDSLINE MED/90332494
Altmann LK
Cuddle aid.
Nurs Times. 1990 Jul 4-10;86(27):23. Unique Identifier : AIDSLINE MED/90332499
Wylie B
AIDS research. A directed strategy.
Nurs Times. 1990 Jul 11-17;86(28):26-8. Unique Identifier : AIDSLINE MED/90332524
Short R
AIDS research. The human side.
Nurs Times. 1990 Jul 11-17;86(28):28-30. Unique Identifier : AIDSLINE MED/90332525
Thomas B
AIDS research. Outlook bleak with brighter patches.
Nurs Times. 1990 Jul 11-17;86(28):32. Unique Identifier : AIDSLINE MED/90332526
de Selincourt K
Misgivings about AIDS transmission: an informal look.
Psychol Rep. 1990 Jun;66(3 Pt 1):810. Unique Identifier : AIDSLINE MED/90332873
Trinkaus J; Chow MB; Baruch College, New York, NY 10010.
Differences between blood donors and nondonors in AIDS-related attitudes.
Psychol Rep. 1990 Jun;66(3 Pt 1):867-70. Unique Identifier : AIDSLINE MED/90332883
LoBello SG; Department of Psychology, Auburn University, Montgomery, Alabama; 36117-3596.
Subjects self-identified as occasional blood donors or nondonors completed a survey to estimate differences in attitudes about donating blood. Subjects who had never donated blood were more likely than occasional donors to doubt that the blood supply was free of the AIDS virus, more likely to worry about contracting A


[Herpes simplex infections in patients with AIDS]
Rev Clin Esp. 1990 Mar;186(5):224-6. Unique Identifier : AIDSLINE MED/90333041
Roustan Gullon G; Hospital Gil M; Roca Arbones V; Valls Jimenez V; Sanchez Yus E; Robledo Aguilar A; Servicio de Dermatologia, Hospital Clinico, San Carlos, Madrid.
Herpes type infections in AIDS patients tend to be more severe, generalized and have a torpid evolution. We present here two cases of intravenous drug addicts with a clinical picture of ulcerative lesions with a scar in the perioral and ungual regions with an evolution of several months an which were diagnosed of Herp


[Kaposi's sarcoma in a HIV-negative patient with kidney transplant (letter)]
Rev Clin Esp. 1990 Mar;186(5):241. Unique Identifier : AIDSLINE MED/90333045
Zamora Martinez E; Gutierrez Ortega MC; Martin Moreno L; de Castro Torres A
[Abdominal adenopathies in patients with tuberculosis and AIDS (letter)]
Rev Clin Esp. 1990 Mar;186(5):241-2. Unique Identifier : AIDSLINE MED/90333046
Laguna Cuesta F; Chimeno Herrero P
[Diagnostic definition of cerebral lesions in a case of AIDS: importance of the use of magnetic resonance]
Recenti Prog Med. 1990 May;81(5):327-8. Unique Identifier : AIDSLINE MED/90333105
Tinelli M; Pricca P; Maccabruni A; Istituto di Clinica di Malattie infettive, Universita, Pavia.
The present study describes a case of AIDS with asymptomatic intracranial focal lesions. The DDD-enhancement CT technique detected the lesions as inflammatory or neoplastic. A subsequent MR demonstrated the vascular nature of the intracranial findings. MR in the neuropathology of AIDS can be of primary importance in t


Pediatric AIDS: adolescence, delinquency, drug abuse, and AIDS.
Tex Med. 1990 Jul;86(7):100-3. Unique Identifier : AIDSLINE MED/90333383
Mangos JA; Doran T; Aranda-Naranjo B; Rodriguez-Escobar Y; Scott A; Setzer JR; Sherman JO; Kossman SP; Department of Pediatrics, University of Texas Health Science; Center, San Antonio 78284-7802.
Sexual promiscuity often is part of the lifestyle of teenagers who are delinquent and abuse drugs, and that behavior puts them at increased risk of contracting HIV infection/AIDS. Many of these juveniles are runaways or live in disorganized homes, and as a result they are hard to reach and it is extremely difficult to


Contact tracing of AIDS, HIV-infected persons approved [news]
Tex Med. 1990 Jul;86(7):39. Unique Identifier : AIDSLINE MED/90333389
How big is the AIDS problem? [news]
Todays OR Nurse. 1990 Jul;12(7):37. Unique Identifier : AIDSLINE MED/90333472
[HIV-1 prevalence in deaths caused by drug overdose in various large cities of West Germany and West Berlin between 1985 and 1988]
Z Rechtsmed. 1990;103(6):407-14. Unique Identifier : AIDSLINE MED/90333784
Puschel K; Mohsenian F; Bornemann R; Bschor F; Schneider V; Penning R; Spann W; von Karger J; Madea B; Metter D; Institut fur Rechtsmedizin, Universitat Hamburg, Bundesrepublik; Deutschland.
The development of the HIV-1-prevalence among drug deaths (n = 753) in several German cities (West Berlin, Frankfurt, Munich, Hamburg, Bremen, Cologne and Stuttgart) from 1985 to 1988 was evaluated; in 1988 43% of 674 deceased drug addicts were examined. The regional prevalence rate was between 15 and 25%; only in Ber


Pneumocystis carinii choroiditis after long-term aerosolized pentamidine therapy [see comments]
Am J Ophthalmol. 1990 Aug 15;110(2):113-7. Unique Identifier : AIDSLINE MED/90334182
Dugel PU; Rao NA; Forster DJ; Chong LP; Frangieh GT; Sattler F; A. Ray Irvine, Jr., Eye Pathology Laboratory, Doheny Eye; Institute, Los Angeles, CA 90033.
Pneumocystis carinii pneumonia is a major cause of morbidity and mortality in patients with the acquired immunodeficiency syndrome. When P. carinii is disseminated, the choroid may be involved and the infection is often fatal. We examined, treated, and followed up two patients who developed choroidal lesions typical o


Retrovir therapy in hemophilic children with symptomatic human immunodeficiency virus infection: efficacy and toxicity.
Am J Pediatr Hematol Oncol. 1990 Summer;12(2):160-3. Unique Identifier : AIDSLINE MED/90334250
Warrier I; Lusher JM; Children's Hospital of Michigan, Wayne State University School of; Medicine, Detroit 48201.
In desperation, we have used retrovir in five hemophilic children (10-16 years old) over the past 22 months. All had presented with various clinical manifestations of acquired-immune-deficiency-syndrome (AIDS)-related complex or AIDS. Our decision to treat with retrovir was based on clinical manifestations and very lo


Mycobacterium avium-intracellulare infections after allogeneic bone marrow transplantation in children.
Am J Pediatr Hematol Oncol. 1990 Summer;12(2):220-4. Unique Identifier : AIDSLINE MED/90334263
Ozkaynak MF; Lenarsky C; Kohn D; Weinberg K; Parkman R; Division of Hematology/Oncology, Children's Hospital of Los; Angeles 90027.
Serious infections caused by the Mycobacterium avium-intracellulare (MAI) complex have been increasingly recognized in patients with acquired immunodeficiency syndrome (AIDS). Allogeneic bone marrow transplant recipients are prone to infections caused by a wide spectrum of organisms. However, infection with MAI has be


A structured psychiatric intervention for cancer patients. I. Changes over time in methods of coping and affective disturbance.
Arch Gen Psychiatry. 1990 Aug;47(8):720-5. Unique Identifier : AIDSLINE MED/90334494
Fawzy FI; Cousins N; Fawzy NW; Kemeny ME; Elashoff R; Morton D; Department of Psychiatry, UCLA School of Medicine.
We evaluated the immediate and long-term effects on psychological distress and coping methods of a 6-week, structured, psychiatric group intervention for postsurgical patients with malignant melanoma. The intervention consisted of health education, enhancement of problem-solving skills, stress management (eg, relaxati


Infection with human immunodeficiency virus and vulnerability to psychiatric distress. A study of men with hemophilia.
Arch Gen Psychiatry. 1990 Aug;47(8):737-44. Unique Identifier : AIDSLINE MED/90334496
Dew MA; Ragni MV; Nimorwicz P; Department of Psychiatry, University of Pittsburgh, School of; Medicine, PA 15213.
We examined psychiatric correlates of human immunodeficiency virus (HIV) infection in a major risk group for acquired immunodeficiency syndrome, men with hemophilia. A central goal was to identify psychosocial factors associated with increased vulnerability to psychiatric distress after infection with HIV. Seventy-fiv


Nasopharyngeal lymphatic tissue in patients infected with human immunodeficiency virus. A prospective clinicopathologic study.
Arch Otolaryngol Head Neck Surg. 1990 Aug;116(8):928-31. Unique Identifier : AIDSLINE MED/90334818
Barzan L; Carbone A; Tirelli U; Crosato IM; Vaccher E; Volpe R; Comoretto R; Division of Otolaryngology, Ospedale Civile, Pordenone, Italy.
A prospective clinicopathologic study of the nasopharyngeal lymphatic tissue, using a standardized approach, was carried out in 66 patients infected with human immunodeficiency virus (HIV) in Aviano, Italy . Two hundred eighteen patients without HIV infection served as a control grou


Progress in infection control practices of Wisconsin dentists: 1986 & 1989 statewide surveys.
WDA J. 1990 Apr;66(4):233-9. Unique Identifier : AIDSLINE MED/90334875
Jones RB
High frequency of human T-cell leukemia-lymphoma virus type II infection in New Mexico blood donors: determination by sequence-specific oligonucleotide hybridization.
Blood. 1990 Aug 1;76(3):450-4. Unique Identifier : AIDSLINE MED/90335428
Hjelle B; Scalf R; Swenson S; Department of Pathology, University of New Mexico School of; Medicine, Albuquerque 87131.
The Albuquerque branch of the United Blood Services system was found to have an unusually high blood donor human T-cell leukemia/lymphoma virus (HTLV) seroprevalence (0.72 per 1,000). Many studies investigating HTLV seroprevalence and transmission have assumed that all seropositivity is due to HTLV type I (HTLV-I); re


Safety of antithrombin III concentrate [letter; comment]
Blood. 1990 Aug 1;76(3):649-50. Unique Identifier : AIDSLINE MED/90335458
Makris M
Thailand and AIDS [news]
Br J Addict. 1990 Jun;85(6):817. Unique Identifier : AIDSLINE MED/90335471
Farrell M
Irish condom ruling [news]
BMJ. 1990 Jun 2;300(6737):1420-1. Unique Identifier : AIDSLINE MED/90335491
Nowlan D
The case against HIV antibody testing of refugees and immigrants [letter]
Can Med Assoc J. 1990 Aug 1;143(3):172-3. Unique Identifier : AIDSLINE MED/90335721
Hall PF
AIDS threat leads to changes in production of gloves, needles [news]
Can Med Assoc J. 1990 Aug 1;143(3):204. Unique Identifier : AIDSLINE MED/90335730
Failure of ADCC to predict HIV-associated disease progression or outcome in a haemophiliac cohort.
Clin Exp Immunol. 1990 Jul;81(1):5-10. Unique Identifier : AIDSLINE MED/90336133
Dalgleish A; Sinclair A; Steel M; Beatson D; Ludlam C; Habeshaw J; Retrovirus Research Group, MRC Clinical Research Centre, Harrow,; UK.
Antibody-dependent cell-mediated cytotoxicity (ADCC) has been described in a number of virus infections and occurs in HIV infection. In spite of numerous studies on the ability of HIV-positive sera to mediate ADCC, it remains unclear whether ADCC has any functional significance. Here we examine serial serum samples fr


Effects of cellular fixatives on human immunodeficiency virus production.
Cytometry. 1990;11(5):647-51. Unique Identifier : AIDSLINE MED/90336468
Cory JM; Rapp F; Ohlsson-Wilhelm BM; Department of Microbiology and Immunology, Pennsylvania State; University College of Medicine, Hershey 17033.
Effects of cell fixation procedures appropriate for flow cytometric analysis on the infectivity of human T lymphoblastoid H9 cells infected with human immunodeficiency virus-1 (HIV-1) were evaluated to provide guidelines for choosing cell treatments for potentially infectious samples. H9 cells experimentally infected


Elimination of high titre HIV from fibreoptic endoscopes [see comments]
Gut. 1990 Jun;31(6):657-9. Unique Identifier : AIDSLINE MED/90337423
Hanson PJ; Gor D; Jeffries DJ; Collins JV; Department of Medicine, Westminster Hospital, London.
Concern about contamination of fibreoptic endoscopes with human immunodeficiency virus (HIV) has generated a variety of disruptive and possibly unnecessary infection control practices in endoscopy units. Current recommendations on the cleaning and disinfection of endoscopes have been formulated without applied experim


[AIDS--how much anxiety can the human mind tolerate? Sexual guilt anxiety--the death drive--solidarity of suspicion]
Fortschr Med. 1990 Jun 30;108(19):70. Unique Identifier : AIDSLINE MED/90337485
Kruger S; Fortschritte der Medizin, Munchen.
The stresses of hospitalization among AIDS patients on integrated and special care units.
Int J Nurs Stud. 1990;27(3):235-47. Unique Identifier : AIDSLINE MED/90337620
van Servellen G; Lewis CE; Leake B; Psychiatric Mental Health Nursing and Administration Section,; School of Nursing, Los Angeles, CA 90024-1702.
This study examined the stresses of hospitalization in AIDS patients and assessed the extent to which two different inpatient delivery systems differed with respect to perceived stresses in these patients. Patients from four AIDS dedicated special care units (SCU s) and five AIDS integrated units (IU s) in eight acute


[Information--a tool in the campaign against AIDS in Mozambique]
Jordemodern. 1990 Jun;103(6):220-3. Unique Identifier : AIDSLINE MED/90337818
Jangsten E; Staaf A
[Computed tomography aspects of cerebral toxoplasmosis in AIDS]
J Belge Radiol. 1990 Jun;73(3):162-72. Unique Identifier : AIDSLINE MED/90337905
Wery D; Lemort M; Catteau A; Hermans P; Clumeck N; Jeanmart L; Service de Radiodiagnostic, Institut J. Bordet et Hopital; St-Pierre, ULB, Bruxelles, Belgique.
We followed by CT 19 AIDS patients with cerebral toxoplasmosis. Diagnosis of cerebral toxoplasmosis was assessed on radiological and clinical basis, including the therapeutic response. CT allowed to confirm brain lesions (40 lesions in 19 patients) and to follow the evolution with treatment. Analysis of the CT feature


Growth hormone mediates the growth of T-lymphoblast cell lines via locally generated insulin-like growth factor-I.
J Clin Endocrinol Metab. 1990 Aug;71(2):464-9. Unique Identifier : AIDSLINE MED/90338319
Geffner ME; Bersch N; Lippe BM; Rosenfeld RG; Hintz RL; Golde DW; Department of Pediatrics, University of California, Los Angeles; Medical Center 90024.
It has become evident that locally produced insulin-like growth factors-I and -II (IGF-I and IGF-II) play an important role in the medication of GH action upon tissues. To explore this concept with respect to immunocompetent cells, we analyzed IGF production and clonogenic responsiveness of immortalized human T-cell l


Serovars of Mycobacterium avium complex isolated from patients in Sweden.
J Clin Microbiol. 1990 Jun;28(6):1105-7. Unique Identifier : AIDSLINE MED/90338339
Hoffner SE; Kallenius G; Petrini B; Brennan PJ; Tsang AY; National Bacteriological Laboratory and Karolinska Institute,; Stockholm, Sweden.
The serovars of clinical isolates of Mycobacterium avium complex from 24 acquired immunodeficiency syndrome (AIDS) and 140 non-AIDS patients in Sweden were studied by using type-specific antisera. A wide distribution of serovars was seen. Serovar 6 was predominant in both groups of


Semiquantitative technique for estimating Pneumocystis carinii burden in the lung.
J Clin Microbiol. 1990 Jun;28(6):1425-7. Unique Identifier : AIDSLINE MED/90338398
Baughman RP; Strohofer S; Colangelo G; Frame PT; Department of Medicine, University of Cincinnati Medical Center,; Ohio 45267-0564.
We developed a technique to estimate the amount of Pneumocystis carinii found in bronchoalveolar lavage fluid. P. carinii associated with 500 nucleated cells in the bronchoalveolar lavage fluid had little between-observer and within-observer variation. Varying the technique of the lavage did not change the amount of P


Simple, sensitive, and specific detection of human immunodeficiency virus type 1 in clinical specimens by polymerase chain reaction with nested primers.
J Clin Microbiol. 1990 Jul;28(7):1560-4. Unique Identifier : AIDSLINE MED/90338435
Albert J; Fenyo EM; Department of Virology, National Bacteriological Laboratory,; Stockholm, Sweden.
A simple, sensitive, and specific polymerase chain reaction (PCR) protocol for the detection of human immunodeficiency virus type 1 (HIV-1) is described. We have improved all three PCR steps: sample preparation, DNA amplification, and detection of the amplified product. Some of the improvements have been described pre


Plasma fibronectin concentrations in patients with human immunodeficiency virus infection.
J Clin Pathol. 1990 Jul;43(7):560-2. Unique Identifier : AIDSLINE MED/90338500
Torre D; Issi M; Sampietro C; Fiori GP; Chelazzi G; Ferraro G; Division of Infectious Diseases, Regional Hospital and Foundation; E and S Macchi, Verese, Italy.
Plasma fibronectin (PFN) concentrations were assessed in 21 patients with AIDS, in seven with AIDS-related complex (ARC), in 17 asymptomatic seropositive patients, and in 36 age and sex matched healthy control subjects. A single radial immunodiffusion technique was used to determine PFN concentration. A significant de


Application of immunoblotting to detect soluble Pneumocystis carinii antigen(s) in bronchoalveolar lavage of patients with Pneumocystis pneumonia and AIDS.
J Clin Pathol. 1990 Jul;43(7):584-6. Unique Identifier : AIDSLINE MED/90338506
Sethi KK; PROGEN Biotechnik GmbH, Im Neuenheimer Feld, Heidelberg, West; Germany.
The technique of immunoblotting for detecting soluble Pneumocystis carinii antigen(s) in bronchoalveolar lavage fluid specimens from patients with AIDS and Pneumocystis pneumonia was evaluated. A soluble 67 kilodalton polypeptide that was immunoreactive with an anti-P carinii monoclonal antibody (2G2) was found in the


[Unusual causes of hemoperitoneum of genital origin]
J Gynecol Obstet Biol Reprod (Paris). 1990;19(4):441-5. Unique Identifier : AIDSLINE MED/90338675
Picaud A; Bennani S; Mba Allo L; Mouely G; Nlome-Nze AR; Ogowet-Igumu N; Departement de Gynecologie Obstetrique, Centre Hospitalier; Universitaire, Libreville, Gabon.
Extra-uterine pregnancy is the most common emergency in gynaecology and obstetrics in the Hospital Centre of Libreville, and the diagnosis of blood in the peritoneal cavity is synonymous with extra-uterine pregnancy. All the same, when the authors reviewed 429 cases of haemoperitoneum 17 were shown not to be due to ec


A polyanion binding site on the CD4 molecule. Proximity to the HIV-gp120 binding region.
J Immunol. 1990 Aug 15;145(4):1188-95. Unique Identifier : AIDSLINE MED/90338752
Parish CR; Low L; Warren HS; Cunningham AL; Division of Cell Biology, John Curtin School of Medical Research,; Australian National University, Canberra.
Recent studies have demonstrated that sulfated polyanions (SP) are potent inhibitors of HIV infection in vitro, appearing to inhibit virus attachment. To understand the mode of action of these compounds a large panel of SP were examined for their ability to inhibit HIV infection, block anti-CD4 mAb binding and, when i


Covalently linked peptides for enzyme-linked immunosorbent assay.
J Immunol Methods. 1990 Jul 20;131(1):99-104. Unique Identifier : AIDSLINE MED/90338789
Sondergard-Andersen J; Lauritzen E; Lind K; Holm A; Research Center for Medical Biotechnology, Statens Seruminstitut,; Copenhagen, Denmark.
A general method is described, by which synthetic peptides are covalently linked via their carboxyl group to microtiter plates (CovaLink) for enzyme-linked immunosorbent assay (ELISA). Plates were prepared by this method with an angiotensin II peptide and with an HIV-2 peptide and attachment detected by rabbit anti-an


Services for persons with AIDS. Nurse executives report.
J Nurs Adm. 1990 Jul-Aug;20(7-8):44-8. Unique Identifier : AIDSLINE MED/90339152
Sowell RL; Fuszard B; Gritzmacher D; University of South Carolina, Columbia.
The increasing number of persons with AIDS (PWAs) requiring healthcare services is a challenge to the organization and delivery of healthcare in the United States . The extent of these services is unclear. In this article, nurse executives report what services for PWAs presently exist o


Toward the year 2000. Challenges to the occupational physician.
J Occup Med. 1990 Jun;32(6):524-8. Unique Identifier : AIDSLINE MED/90339182
Warshaw LJ; New York Business Group on Health, Inc., NY 10017-6763.
Ultrastructure of the jejunal mucosa in human immunodeficiency virus infection.
J Pathol. 1990 Jun;161(2):119-27. Unique Identifier : AIDSLINE MED/90339189
Mathan MM; Griffin GE; Miller A; Batman P; Forster S; Pinching A; Harris W; Wellcome Research Unit, Christian Medical College Hospital,; Vellore, India.
The ultrastructural changes in the jejunal mucosa of 11 male patients, three with clinical AIDS, five with AIDS related complex-progressive generalized lymphadenopathy (ARC-PGL), and three who were only HIV antibody positive, were studied. In the enterocytes, major abnormalities were proliferation of smooth endoplasmi


Respiratory syncytial virus infection in human immunodeficiency virus-infected children.
J Pediatr. 1990 Aug;117(2 Pt 1):251-4. Unique Identifier : AIDSLINE MED/90339216
Chandwani S; Borkowsky W; Krasinski K; Lawrence R; Welliver R; Department of Pediatrics, New York University Medical Center, New; York 10016.
Interpretation of western blots of specimens from children infected with human immunodeficiency virus type 1: implications for prognosis and diagnosis.
J Pediatr. 1990 Aug;117(2 Pt 1):255-8. Unique Identifier : AIDSLINE MED/90339217
Walter EB; McKinney RE; Lane BA; Weinhold KJ; Wilfert CM; Department of Pediatrics, Duke University Medical Center, Durham,; North Carolina 27710.
Surgical procedures in patients at risk of human immunodeficiency virus infection [see comments]
J R Soc Med. 1990 May;83(5):315-8. Unique Identifier : AIDSLINE MED/90339418
Wakeman R; Johnson CD; Wastell C; Professorial Surgical Unit, St Stephen's Hospital, London.
We have studied the outcome of 140 general surgical procedures in 112 patients known or suspected to be infected with human immunodeficiency virus (HIV) or hepatitis B virus. Forty patients had antibodies to HIV. A wide range of surgical procedures was performed, with an overall complication rate of 5.7%. Wound infect


AIDS afterthought [editorial]
J R Soc Med. 1990 Jun;83(6):346-7. Unique Identifier : AIDSLINE MED/90339435
Goldman J
Pulmonary Mycobacterium xenopi infection as a first manifestation of HIV infection.
J R Soc Med. 1990 Jun;83(6):401-2. Unique Identifier : AIDSLINE MED/90339454
Wilks D; George RJ; Spiro SJ; University College Hospital, London.
19th annual UCLA symposium: Animal models of human viral diseases: relevance to developmental therapeutics. Abstracts.
J Cell Biochem Suppl. 1990;14D:41-75. Unique Identifier : AIDSLINE MED/90339883
19th annual UCLA symposium: HIV and AIDS: pathogenesis, therapy and vaccine. Abstracts.
J Cell Biochem Suppl. 1990;14D:77-181. Unique Identifier : AIDSLINE MED/90339884
[Type-2 human immunodeficiency virus: a study in the central region (communities of Madrid and Castilla La Mancha (letter)]
Med Clin (Barc). 1990 Apr 28;94(16):638. Unique Identifier : AIDSLINE MED/90339912
Cour MJ; Gonzalez Cuadrado S; Fernandez ME; Ladron de Guevara J
[Effectiveness of thalidomide in non specific esophageal ulcer in patients with acquired immunodeficiency syndrome (letter)]
Med Clin (Barc). 1990 Apr 28;94(16):638-9. Unique Identifier : AIDSLINE MED/90339913
Bernardo P; Arrizabalaga J; Iribarren JA; Garde C
[Hodgkin's lymphoma and Kaposi's sarcoma. Infrequent association in acquired immunodeficiency syndrome (letter)]
Med Clin (Barc). 1990 Apr 28;94(16):639. Unique Identifier : AIDSLINE MED/90339914
Salinas-Argente R; Sans-Sabrafen J; Buxo J; Font L
[Inhibition of alfa interferon and ampligen of human immunodeficiency virus (HIV) replication in monocyte-macrophage subpopulations]
Medicina (Firenze). 1990 Jan-Mar;10(1):34-6. Unique Identifier : AIDSLINE MED/90339977
Bergamini A; Ercoli L; Perno CF; Dipartimento di Sanita Pubblica, Universita di Roma Tor; Vergata.
Levels of replication of HIV in two different populations of monocyte/macrophages (M/M) at different stages of maturation were evaluated, as well as the antiviral activity of alpha-interferon (alpha-IFN) and Ampligen (an inductor of endogenous production of alpha-IFN). HIV replication was found to be 5-10 times greate


[Visiting the nurses of Bulgaria (3 days in the Bulgarian city of Tolbukhin)]
Med Sestra. 1990 May;49(5):12-6. Unique Identifier : AIDSLINE MED/90339992
Petrovskaia TD
HIV-related risk-taking behaviour, knowledge and serostatus of intravenous drug users in Sydney.
Med J Aust. 1990 May 7;152(9):453-8. Unique Identifier : AIDSLINE MED/90340160
Wolk J; Wodak A; Morlet A; Guinan JJ; Gold J; Albion Street (AIDS) Centre, Surry Hills, NSW.
This study was carried out in 1987 to investigate the relationships between human immunodeficiency virus (HIV)-related risk-taking behaviour, demographic characteristics and serostatus of 181 intravenous drug users in Sydney. Subjects were predominantly heterosexual men in their late twenties with limited secondary ed


Homeless youth and AIDS: knowledge, attitudes and behaviour.
Med J Aust. 1990 Jul 2;153(1):20-3. Unique Identifier : AIDSLINE MED/90340190
Matthews BR; Richardson KD; Price J; Williams G; Royal Brisbane Hospital, Herston, QLD.
A study conducted in Brisbane, Queensland, assessed homeless youths knowledge, attitudes and behaviours relating to acquired immunodeficiency syndrome (AIDS). Data obtained from 40 homeless youths aged 15 to 19 years were compared with that from controls. The findings identified a significantly lower level of accurat


HIV testing of hospital patients.
Med J Aust. 1990 Jul 2;153(1):50-3. Unique Identifier : AIDSLINE MED/90340199
Wright GD; Flinders Medical Centre, Bedford Park, SA.
This article sets out the issues involved in the development of hospital policy that will allow or require human immunodeficiency virus (HIV) testing of patients in hospital. It considers the shared and competing interests of patients and staff, and the obligations of employers to worker health and safety. It shows th


A disease of society: cultural responses to AIDS (Part 1).
Milbank Q. 1990;68 Suppl 1:1-174. Unique Identifier : AIDSLINE MED/90340229
A disease of society: cultural responses to AIDS (Part 1). Introduction.
Milbank Q. 1990;68 Suppl 1:1-9. Unique Identifier : AIDSLINE MED/90340230
Nelkin D; Willis DP; Parris SV
The social impact of AIDS in Sub-Saharan Africa.
Milbank Q. 1990;68 Suppl 1:10-32. Unique Identifier : AIDSLINE MED/90340231
van de Walle E; University of Pennsylvania.
The potential expansion of the HIV epidemic and its cultural impact in sub-Saharan Africa are vast. Projections under conservative assumptions suggest that the toll of AIDS will reach five million annual deaths by 2010, although the net African population will continue to increase significantly. Cultural practices, in


AIDS and the rights of the individual: toward a more sophisticated understanding of discrimination.
Milbank Q. 1990;68 Suppl 1:143-74. Unique Identifier : AIDSLINE MED/90340233
Stoddard TB; Rieman W; Lambda Legal Defense and Education Fund, New York.
AIDS is the first public health crisis in America to arise after the mid-century civil rights revolution. Reflecting the values of the civil rights movement, public health experts have drawn attention to the dangers of discrimination against individuals who are sick or at risk, and generally have expressed a preferenc


AIDS and changing concepts of family.
Milbank Q. 1990;68 Suppl 1:33-58. Unique Identifier : AIDSLINE MED/90340234
Levine C; Citizens Commission on AIDS for New York City and Northern New; Jersey, NY 10013.
The family in contemporary America may be defined as a group of individuals who by birth, adoption, marriage, or declared commitment share deep personal connections and are mutually entitled to receive, and obligated to provide, support of various kinds. As more people live in nontraditional arrangements, the gap betw


Coming of age in the era of AIDS: puberty, sexuality, and contraception.
Milbank Q. 1990;68 Suppl 1:59-84. Unique Identifier : AIDSLINE MED/90340235
Brooks-Gunn J; Furstenberg FF Jr; Educational Testing Service; University of Pennsylvania.
The existing discrepancies between adolescent and societal constructions of teenage sexuality in America are further exacerbated by AIDS. Male and female teenagers receive different and often conflicting messages about sexuality from diverse sources; their parents lack of frankness about sexual intercourse contrasts


AIDS and the social relations of intravenous drug users [published erratum appears in Milbank Q 1990;68(1):142]
Milbank Q. 1990;68 Suppl 1:85-110. Unique Identifier : AIDSLINE MED/90340236
Friedman SR; Des Jarlais DC; Sterk CE; Sotheran JL; Tross S; Woods J; Sufian M; Abdul-Quader A; Narcotic and Drug Research, Inc., New York.
Gauging the impact of AIDS on intravenous drug users requires analysis of the cultural, political, and racial contexts of American society in which drug use is embedded. Considerable variation in behavior among drug injectors and noninjectors in different cities over time further complicates an understanding of the dy


AIDS and the future of reproductive freedom.
Milbank Q. 1990;68 Suppl 2:179-204. Unique Identifier : AIDSLINE MED/90340237
Bayer R; Columbia University.
The specter of pediatric AIDS fundamentally challenges elements of the liberal ideological basis of women s reproductive freedom. Many public health officials hold that preventing transmission of HIV from mother to fetus requires efforts to discourage pregnancy by infected women. For over two decades, however, genetic


A disease of society: cultural responses to AIDS (Part 2).
Milbank Q. 1990;68 Suppl 2:179-319. Unique Identifier : AIDSLINE MED/90340238
The poisoned gift: AIDS and blood.
Milbank Q. 1990;68 Suppl 2:205-25. Unique Identifier : AIDSLINE MED/90340239
Murray TH; Case Western Reserve University.
The moral and communal ends served by a system of gifts of blood have been threatened by the fear of AIDS transmission. Blood banks and those at risk for HIV infection have made changes in their practices to reduce the risk to recipients, and physicians and patients now understand better that blood carries risks and s


The culture of caring: AIDS and the nursing profession.
Milbank Q. 1990;68 Suppl 2:226-56. Unique Identifier : AIDSLINE MED/90340240
Fox RC; Aiken LH; Messikomer CM; University of Pennsylvania.
Caring for persons with AIDS calls upon a range of physical, psychological, social, and spiritual interventions that, in the absence of a cure, can make a palpable difference for patients. The culture of caring that nurses bring to bear on the epidemic is shaped by their education and socialization, and by shared back


AIDS and its impact on medical work: the culture and politics of the shop floor.
Milbank Q. 1990;68 Suppl 2:257-79. Unique Identifier : AIDSLINE MED/90340241
Bosk CL; Frader JE; University of Pennsylvania.
AIDS, together with other institutional factors, is changing the shop-floor culture of house officers and students in urban, academic medical centers. These medical workers complained of powerlessness and exploitation prior to the epidemic, but they felt pride in scoring clinical coups and chagrin in their clinical de


AIDS and volunteer associations: perspectives on social and individual change.
Milbank Q. 1990;68 Suppl 2:280-94. Unique Identifier : AIDSLINE MED/90340242
Kobasa SC; City University of New York.
In dealing with AIDS, American volunteer associations exemplify Tocqueville s classic analysis of their function: the call for government to address social needs, monitor government shortcomings, and serve those needs beyond the government s compass. Individual volunteers experience in the epidemic have often empower


The implicated and the immune: cultural responses to AIDS.
Milbank Q. 1990;68 Suppl 2:295-319. Unique Identifier : AIDSLINE MED/90340243
Goldstein R
Unlike previous epidemics in American history, AIDS has spawned a host of creative works in the arts and mass media. Representations in the fine arts have emphasized perspectives of the insider or the implicated, i.e., people with AIDS, while commercial programs and performers in popular culture have adopted the vanta


Avoiding exposure to HIV by needle stick [letter]
N Engl J Med. 1990 Aug 30;323(9):611-2. Unique Identifier : AIDSLINE MED/90340364
Renschler MF
Retroviruses and multiple sclerosis. I. Analysis of seroreactivity by western blot and radioimmune assay.
Neurology. 1990 Aug;40(8):1251-3. Unique Identifier : AIDSLINE MED/90340497
Weinshenker BG; Dekaban G; Rice GP; University Hospital, London, ON, Canada.
We were unable to identify an antibody to either HTLV-I or HIV-1 in patients with multiple sclerosis (MS) by ELISA, by radioimmune assay, or by radioimmune precipitation techniques. Immunoblot studies for HTLV-I-specific antibodies revealed faintly reactive bands in 2 of 44 MS patients but not in patients with other n


Retroviruses and multiple sclerosis. II. Failure of gene amplification techniques to detect viral sequences unique to the disease.
Neurology. 1990 Aug;40(8):1254-8. Unique Identifier : AIDSLINE MED/90340498
Dekaban GA; Rice GP; University Hospital, London, ON, Canada.
Multiple sclerosis (MS) has been associated with infection by a novel human retrovirus because of its similarity to other white matter diseases caused by retroviruses and because of some serologic evidence suggesting reactivity of MS sera with antigens of HTLV-I. With the polymerase chain reaction technique, we attemp


Demyelinating changes in sural nerve biopsy of patients with HTLV-I-associated myelopathy.
Neurology. 1990 Aug;40(8):1263-6. Unique Identifier : AIDSLINE MED/90340500
Sugimura K; Takahashi A; Watanabe M; Mano K; Watanabe H; Department of Neurology, Nagoya University School of Medicine,; Japan.
We describe the sural nerve pathology in 3 patients with HTLV-I-associated myelopathy (HAM). These patients showed remarkable symptoms of myelopathy and had high HTLV-I titers in the serum and CSF. The common pathologic findings in the sural nerves were as follows: slightly decreased density in myelinated fibers (6,56


Excessive muscular fatigue in patients with spastic paraparesis.
Neurology. 1990 Aug;40(8):1271-4. Unique Identifier : AIDSLINE MED/90340502
Miller RG; Green AT; Moussavi RS; Carson PJ; Weiner MW; Department of Neurology, Children's Hospital of San Francisco, CA; 94118.
We used intermittent tetanic contractions and 31P magnetic resonance spectroscopy to investigate human tibialis anterior muscle metabolism and fatigability in a group of patients with spastic paraparesis and in normal controls. During intermittent tetanic stimulation, the decline in tension was significantly greater i


Cocktail vaccine may protect against HIV [news]
Nursing (Lond). 1990 Jul 12-25;4(14):8. Unique Identifier : AIDSLINE MED/90340598
Gee CF
Routine human immunodeficiency virus infection screening of women requesting induced first-trimester abortion in an inner-city population.
Obstet Gynecol. 1990 Sep;76(3 Pt 1):347-50. Unique Identifier : AIDSLINE MED/90340628
Lindsay MK; Peterson HB; Taylor EB; Blunt M; Willis S; Klein L; Department of Gynecology and Obstetrics, Emory University School; of Medicine, Atlanta, Georgia.
Infection with the human immunodeficiency virus (HIV) among reproductive-age women occurs disproportionately among inner-city minority populations. These women are at risk because of intravenous drug abuse and heterosexual transmission from partners infected through drug abuse. From July 1, 1988 to December 31, 1988,


Acquired immunodeficiency syndrome and Pneumocystis carinii infection in a pregnant woman.
Obstet Gynecol. 1990 Sep;76(3 Pt 2):480-1. Unique Identifier : AIDSLINE MED/90340657
Hicks ML; Nolan GH; Maxwell SL; Mickle C; Department of Gynecology and Obstetrics, Henry Ford Hospital,; Detroit, Michigan.
Human immunodeficiency virus (HIV) infections are being seen with greater regularity by the obstetrician-gynecologist. Acquired immunodeficiency syndrome (AIDS), the extreme of the spectrum of HIV infections, is associated with Pneumocystis carinii infection in more than half of newly diagnosed cases. Four cases of AI


HIV threat to everyone [news]
Occup Health (Lond). 1990 Jul;42(7):191. Unique Identifier : AIDSLINE MED/90340687
Destruction of surgical instruments following use of disinfectants to eradicate human immunodeficiency virus [letter]
Ophthalmic Surg. 1990 Jun;21(6):453-4. Unique Identifier : AIDSLINE MED/90340786
Wesley RE
New pediatric AIDS clinics for families [news]
Pa Med. 1990 Jul;93(7):9-10. Unique Identifier : AIDSLINE MED/90340858
The impact of AIDS on nursing education.
Pa Nurse. 1990 Aug;45(8):1, 6, 8 passim. Unique Identifier : AIDSLINE MED/90340865
Hurley P; McGriff EP
Providing quality of life for AIDS patients: Eagle's Wings Project.
Pa Nurse. 1990 Aug;45(8):20, 7. Unique Identifier : AIDSLINE MED/90340869
Dahir MS
[New AIDS medications]
Nor Tannlaegeforen Tid. 1990 Jan;100(1):50. Unique Identifier : AIDSLINE MED/90340956
[Duty to trace origins of infections (HIV)]
Nor Tannlaegeforen Tid. 1990 Jan;100(1):52. Unique Identifier : AIDSLINE MED/90340957
Lystad A
[Abuse of drugs: main cause of HIV spread in the 1990s]
Nor Tannlaegeforen Tid. 1990 Jan;100(1):53. Unique Identifier : AIDSLINE MED/90340958
[HIV-positive males and prostitution]
Nor Tannlaegeforen Tid. 1990 Jan;100(1):54. Unique Identifier : AIDSLINE MED/90340959
Hasseltvedt V
[HIV-positive children]
Nor Tannlaegeforen Tid. 1990 Jan;100(1):56. Unique Identifier : AIDSLINE MED/90340960
Lindemann R; Sande HA; Ravn I; Tronnes L; Hansen BR
[HIV test campaign: It is better to know]
Nor Tannlaegeforen Tid. 1990 Jan;100(1):57. Unique Identifier : AIDSLINE MED/90340961
HIV-positive but not symptomatic.
Nurs Times. 1990 Aug 1-7;86(31):10. Unique Identifier : AIDSLINE MED/90341023
Burger H; Belman A; Grimson R
UKCC slams plans for neonatal HIV tests [news]
Nurs Times. 1990 Aug 1-7;86(31):5. Unique Identifier : AIDSLINE MED/90341038
A sharp lesson.
Nurs Times. 1990 Aug 1-7;86(31):50-1. Unique Identifier : AIDSLINE MED/90341039
Viral etiology of AIDS and the Gallo probe [letter; comment]
Science. 1990 Aug 3;249(4968):465-6. Unique Identifier : AIDSLINE MED/90341756
Pneumococcal bacteremia as a marker for human immunodeficiency virus infection in patients without AIDS.
South Med J. 1990 Aug;83(8):895-9. Unique Identifier : AIDSLINE MED/90341830
Chirurgi VA; Edelstein H; McCabe R; Veterans Administration Medical Center, Martinez, CA 94553.
We retrospectively reviewed medical records of all adult patients with blood cultures positive for Streptococcus pneumoniae to determine the number of HIV seropositive patients in whom S pneumoniae bacteremia was the presenting manifestation. We also compared the clinical presentation, laboratory data, and outcome of


Proctologic management of the HIV-positive patient.
South Med J. 1990 Aug;83(8):900-3. Unique Identifier : AIDSLINE MED/90341831
Beck DE; Jaso RG; Zajac RA; Department of General Surgery, Wilford Hall USAF Medical Center,; Lackland AFB, TX 78236.
With the adoption of mandatory testing for human immunodeficiency virus (HIV) in military personnel, a large number of HIV-positive individuals have been identified. From January 1986 to February 1988, 677 HIV-positive patients were evaluated at Wilford Hall USAF Medical Center. Most of these patients had disease in t


A survey of exposures, practices and recommendations of surgeons in the care of patients with human immunodeficiency virus.
Surg Gynecol Obstet. 1990 Aug;171(2):99-106. Unique Identifier : AIDSLINE MED/90341904
Mandelbrot DA; Smythe WR; Norman SA; Martin SC; Arnold RM; Talbot GH; Stolley PD; Department of Medicine, University of Pennsylvania School of; Medicine, Philadelphia.
Policy makers face a conflict between satisfying concerns of health care workers (HCW) about the occupational risk of human immunodeficiency virus (HIV) infection and ensuring adequate care for patients. This conflict is particularly severe in the field of surgery. We mailed a questionnaire on the surgical care of pat


Chemotherapy and management of tuberculosis in the United Kingdom: recommendations of the Joint Tuberculosis Committee of the British Thoracic Society.
Thorax. 1990 May;45(5):403-8. Unique Identifier : AIDSLINE MED/90341984
Transcarinal needle aspiration in the diagnosis of mediastinal adenitis in a patient infected with the human immunodeficiency virus [see comments]
Thorax. 1990 May;45(5):414-5. Unique Identifier : AIDSLINE MED/90341986
Julia Serda G; Rodriguez de Castro F; Fernandez Sanchez-Alarcos JM; Caminero Luna J; Diaz Lopez F; Cabrera Navarro P; Pulmonary Division, Nuestra Senora del Pino Hospital, Las Palmas; de Gran, Canaria, Spain.
Local activation of the coagulation and fibrinolysis systems in lung disease.
Thromb Res. 1990 Mar 15;57(6):827-38. Unique Identifier : AIDSLINE MED/90341994
Nakstad B; Lyberg T; Skjonsberg OH; Boye NP; Department of Pathology, Ulleval University Hospital, Oslo,; Norway.
Extravascular coagulation and fibrinolysis is an integral part of inflammatory reactions. Disordered expression of procoagulant and profibrinolytic factors by mononuclear phagocytes of the lung (i.e. lung alveolar macrophages (LAM) and interstitial macrophages) may have important bearings on inflammatory lung tissue d


[The effect of thymalin on biochemical and immunological indices of lymphocyte differentiation and functional activity]
Vopr Med Khim. 1990 May-Jun;36(3):41-3. Unique Identifier : AIDSLINE MED/90342297
Khavinson VKh; Kozhemiakin AL; Morozov VG; Kozhemiakin LA
Polypeptide preparation thymalin obtained from thymus was found to normalize the LDH isoenzyme spectrum and cyclase system in lymphocytes of patients. Thymalin contributed also to expression of differentiation antigens on T-lymphocytes surface. As a result of this functional activity of T-lymphocytes was restored, whi


Successful therapy for Toxoplasma gondii myocarditis in acquired immunodeficiency syndrome.
Am Heart J. 1990 Aug;120(2):443-4. Unique Identifier : AIDSLINE MED/90342709
Grange F; Kinney EL; Monsuez JJ; Rybojad M; Derouin F; Khuong MA; Janier M; Department of Dermatology, Hopital Saint-Louis, Paris, France.
Recurrence and clearance of hepatitis B surface antigenemia in a dialysis patient infected with the human immunodeficiency virus.
Am J Kidney Dis. 1990 Aug;16(2):154-6. Unique Identifier : AIDSLINE MED/90342744
Ortiz-Interian CJ; de Medina MD; Perez GO; Bourgoignie JJ; Watkins F; Velez-Robinson E; Schiff E; Division of Nephrology, University of Miami, FL 33101.
Hepatitis B vaccination programs have prevented infection in many dialysis patients, although the antibody response to vaccination is still insufficient in approximately 50%. Reinfection or reactivation of latent hepatitis B infection (HBV) has been reported in certain groups of immunosuppressed patients, including th


Visceral bacillary epithelioid angiomatosis: possible manifestations of disseminated cat scratch disease in the immunocompromised host: a report of two cases.
Am J Med. 1990 Aug;89(2):216-22. Unique Identifier : AIDSLINE MED/90342767
Kemper CA; Lombard CM; Deresinski SC; Tompkins LS; Department of Medicine, Stanford University School of Medicine,; California.
Opportunistic infection with the causative agent of cat scratch disease may be responsible for an unusual vascular proliferative lesion, referred to as bacillary epithelioid angiomatosis, previously described only in human immunodeficiency virus (HIV)-infected patients. We present a case of an HIV-infected patient wit


Response of HIV-associated disseminated cat scratch disease to treatment with doxycycline.
Am J Med. 1990 Aug;89(2):229-31. Unique Identifier : AIDSLINE MED/90342769
Mui BS; Mulligan ME; George WL; Medical Service, West Los Angeles Veterans Administration Medical; Center, California 90073.
Rostral basilar reversible ischemic neurologic deficit in an HIV-infected patient with cryptococcal meningitis [letter]
Am J Med. 1990 Aug;89(2):248-9. Unique Identifier : AIDSLINE MED/90342775
Rafal RD; Friedman JH
Tuberculous polymyositis in HIV infection [letter]
Am J Med. 1990 Aug;89(2):250-1. Unique Identifier : AIDSLINE MED/90342777
Pouchot J; Vinceneux P; Barge J; Laparre F; Boussougant Y; Michon C
Coexistence of AIDS and lupus nephritis: a case report.
Am J Nephrol. 1990;10(3):243-7. Unique Identifier : AIDSLINE MED/90342792
D'Agati V; Seigle R; Department of Pathology, College of Physicians and Surgeons,; Columbia University, New York, N.Y.
We report the first case of membranous lupus nephritis occurring in a child with congenital AIDS. Hypocomplementemia, elevated titers of anti-nuclear antibody and antibody to double-stranded DNA supported the diagnosis of associated systemic lupus erythematosus (SLE). The pathogenetic implications of this coexistence


A group intervention model for individuals testing positive for HIV antibody.
Am J Orthopsychiatry. 1990 Jul;60(3):452-9. Unique Identifier : AIDSLINE MED/90342809
Levy RS; Tendler C; VanDevanter N; Cleary PD; Columbia University School of Public Health, New York.
The development of a structured psychoeducational support group model for blood donors who tested positive for human immunodeficiency virus Type I antibody is described. Salient group therapy techniques and educational content are discussed, issues of group structure are identified, and the need for support of clinici


Demographic characteristics, risk behaviors, and HIV seroprevalence among intravenous drug users by site of contact: results from a community-wide HIV surveillance project.
Am J Public Health. 1990 Sep;80(9):1062-7. Unique Identifier : AIDSLINE MED/90342908
McCusker J; Koblin B; Lewis BF; Sullivan J; School of Public Health, University of Massachusetts, Amherst; 01003.
We investigated differences in behaviors important for human immunodeficiency virus (HIV) transmission and HIV antibody status among 927 recent needle users enrolled in a multi-site HIV surveillance project in Worcester, Massachusetts. Subjects were enrolled at drug abuse treatment centers reported less risky injectio


Impact of the human immunodeficiency virus epidemic on mortality trends in young men, United States.
Am J Public Health. 1990 Sep;80(9):1080-6. Unique Identifier : AIDSLINE MED/90342912
Buehler JW; Devine OJ; Berkelman RL; Chevarley FM; Division of HIV/AIDS, Centers for Disease Control, USPHS,; Atlanta, GA 30333.
Following a long-term decline, death rates in men 25-44 years of age increased from 212 deaths/100,000 in 1983 to 236 deaths/100,000 in 1987. To assess the impact of human immunodeficiency virus (HIV) infections on this trend and to identify causes that are increasing in association with the HIV epidemic, we analyzed


Premarital screening for antibodies to human immunodeficiency virus type 1 in the United States. The Premarital Screening Study Group.
Am J Public Health. 1990 Sep;80(9):1087-90. Unique Identifier : AIDSLINE MED/90342913
Petersen LR; White CR; AIDS Program, Centers for Disease Control, Atlanta, GA 30333.
To evaluate premarital human immunodeficiency virus (HIV) screening as an approach to AIDS prevention in the United States , we determined the HIV antibody seroprevalence in marriage license applicants in eight areas by blinded testing of blood specimens routinely collected for syphilis


HIV seroprevalence and the acceptance of voluntary HIV testing among newly incarcerated male prison inmates in Wisconsin.
Am J Public Health. 1990 Sep;80(9):1129-31. Unique Identifier : AIDSLINE MED/90342926
Hoxie NJ; Vergeront JM; Frisby HR; Pfister JR; Golubjatnikov R; Davis JP; AIDS/HIV Program, Wisconsin Division of Health, Madison; 53701-0309.
In 1986-88, voluntary and blinded HIV testing was conducted among Wisconsin male prison entrants. The HIV seroprevalence was 0.30 percent in 1986, 0.53 percent in 1987, and 0.56 percent in 1988. The seroprevalence rates among entrants tested voluntarily did not differ from those tested blindly. Voluntary HIV testing w


Children with AIDS and skin manifestations [news]
Ann Allergy. 1990 Aug;65(2):A-38. Unique Identifier : AIDSLINE MED/90343103
Nursing care goes high tech.
Am Nurse. 1990 Jul-Aug;22(7):1, 21. Unique Identifier : AIDSLINE MED/90343122
Selby T
Treatment of disseminated Mycobacterium avium complex infection in AIDS with amikacin, ethambutol, rifampin, and ciprofloxacin. California Collaborative Treatment Group [see comments]
Ann Intern Med. 1990 Sep 1;113(5):358-61. Unique Identifier : AIDSLINE MED/90343173
Chiu J; Nussbaum J; Bozzette S; Tilles JG; Young LS; Leedom J; Heseltine PN; McCutchan JA; Division of Infectious Diseases, University of California, Irvine; Medical Center, Orange 92668.
OBJECTIVE: To determine the efficacy of combination drug therapy for disseminated Mycobacterium avium complex infection in patients with the acquired immunodeficiency syndrome (AIDS). DESIGN: Prospective, nonrandomized, before-after comparison. SETTING: Outpatient clinics at three university medical centers. PATIENTS:


Human T-lymphotropic virus (HTLV I-II) infection among patients in an inner-city emergency department.
Ann Intern Med. 1990 Sep 1;113(5):368-72. Unique Identifier : AIDSLINE MED/90343175
Kelen GD; DiGiovanna TA; Lofy L; Junkins E; Stein A; Sivertson KT; Lairmore M; Quinn TC; Johns Hopkins University School of Medicine, Baltimore, Maryland.
OBJECTIVE: To determine the seroprevalence and epidemiologic features of human T-lymphotropic virus (HTLV I-II) among an emergency department patient population with a high rate of human immunodeficiency virus (HIV-1) infection. DESIGN: Prospective survey using identity-unlinked consecutive sampling during a 6-week pe


AIDS, nutrition, and infection [letter; see comments]
Ann Intern Med. 1990 Sep 1;113(5):409-10. Unique Identifier : AIDSLINE MED/90343185
Kendler BS
Chronic localized herpes zoster in the acquired immunodeficiency syndrome [letter] [see comments]
Arch Dermatol. 1990 Aug;126(8):1105-6. Unique Identifier : AIDSLINE MED/90343396
Disler RS; Dover JS
Risks of blood exposure to the cardiac surgical team.
Ann Thorac Surg. 1990 Aug;50(2):248-50. Unique Identifier : AIDSLINE MED/90343504
Pate JW; Department of Surgery, University of Tennessee, Memphis 38163.
The risk of transmission of human immunodeficiency virus from patient to cardiac surgical team is perceived by most people to be very slight, yet the possibility is a valid concern. The feasibility of barrier protection in prevention of this risk is dependent on integrity of surgical gloves and absence of splashes of


Esophageal perforation in a patient with acquired immunodeficiency syndrome.
Ann Thorac Surg. 1990 Aug;50(2):299-300. Unique Identifier : AIDSLINE MED/90343516
Adkins MS; Raccuia JS; Acinapura AJ; Department of Cardiovascular and Thoracic Surgery, St. Vincent's; Hospital and Medical Center, New York, New York.
Infection with Mycobacterium tuberculosis is frequently found in patients with acquired immunodeficiency syndrome and can result in diffuse lymphadenopathy from disseminated disease. A case is presented of esophageal erosion and perforation secondary to mediastinal lymph node enlargement from Mycobacterium tuberculosi


[Perpropionic and peracetic acids destroy HIV in suspension, but do not inhibit the virus in contaminated units of blood]
Rev Fr Transfus Hemobiol. 1990 Mar;33(2):97-100. Unique Identifier : AIDSLINE MED/90343926
Lopez M; Henin Y; Nguyen L; Salmon C; Inserm U-76 et Institut National de Transfusion Sanguine, Paris,; France.
The virucidal activity of peracetic and perpropionic acids was evaluated against HIV in an attempt to inactivate the virus which might contaminate blood units collected from donors. The results showed first that doses of peracids as weak as 50 ppm were able to kill the virus in free suspension, but that the doses that


Perspectives on prevention and medical education for the 1990s.
Am J Prev Med. 1990;6(2 Suppl):1-5. Unique Identifier : AIDSLINE MED/90344283
Nickens HW; Petersdorf RG; Division of Minority Health, Association of American Medical; Colleges, Washington, DC 20036.
Heart disease and stroke have been the first and third leading causes of death, respectively, in the United States for many years, and the importance of primary and secondary prevention in reducing morbidity and mortality from these two disease entities has been well established. Addit


[Beginnings of therapy of manifest HIV infection in adults and in children. Position of the Scientific Advisory Committee of the General Medical Council]
Kinderkrankenschwester. 1990 Feb;9(2):59. Unique Identifier : AIDSLINE MED/90344695
Antisperm antibodies in human immunodeficiency virus infection: effects on fertilization and embryonic development.
Biol Reprod. 1990 May-Jun;42(5-6):859-68. Unique Identifier : AIDSLINE MED/90344952
Naz RK; Ellaurie M; Phillips TM; Hall J; Department of Obstetrics and Gynecology, Albert Einstein College; of Medicine, Bronx, New York 10461.
Sera from human immunodeficiency virus (HIV)-infected males (n = 10) and females (n = 5) were analyzed for the presence of antisperm antibodies reacting against sperm-specific antigens. Of the HIV-positive males tested, sera of 40% were positive for human sperm extract (HSE), 70% for protamine, and 70% for fertilizati


Impact of AIDS on surgery [news] [see comments]
Br J Surg. 1990 Jul;77(7):748. Unique Identifier : AIDSLINE MED/90345169
MacGowan WA
Universal precautions [letter; comment]
Can Med Assoc J. 1990 Aug 15;143(4):256-7. Unique Identifier : AIDSLINE MED/90345350
Righter J
Fighting AIDS in francophone African countries [letter; comment]
Can Med Assoc J. 1990 Aug 15;143(4):257-8. Unique Identifier : AIDSLINE MED/90345351
Boyd N
HIV needs no visa, MD warns [news]
Can Med Assoc J. 1990 Aug 15;143(4):303. Unique Identifier : AIDSLINE MED/90345362
Canada's national AIDS strategy neglects role of physicians [editorial]
Can Med Assoc J. 1990 Aug 15;143(4):309-11. Unique Identifier : AIDSLINE MED/90345364
Berger P
Human T cell leukemia virus type I induces DNA synthesis and immunoglobulin secretion in human lymphocyte cultures.
Cell Immunol. 1990 Sep;129(2):341-50. Unique Identifier : AIDSLINE MED/90345454
Boyer V; Dodon MD; Gazzolo L; Laboratoire d'Immuno-Virologie Moleculaire et Cellulaire, UMR 30; CNRS-UCBL, Faculte de Medecine A. Carrel, Lyon, France.
Viral particles obtained from HTLV-I (human T cell leukemia virus, type I)-transformed T cell lines induced immunoglobulin production by normal peripheral blood lymphocytes. Conversely, no immunoglobulin could be detected in the supernatant medium in purified B cells cultivated with HTLV-I, suggesting that the presenc


[Prevention of human immunodeficiency virus transmission in health personnel]
Chir Dent Fr. 1990 Jan 4-11;60(500-501):100-2. Unique Identifier : AIDSLINE MED/90345743
Localization of aldosterone-producing adenoma: venous sampling in primary aldosteronism.
Endocrinol Jpn. 1990 Feb;37(1):151-7. Unique Identifier : AIDSLINE MED/90345865
Iwaoka T; Umeda T; Naomi S; Miura F; Inoue J; Sasaki M; Hamasaki S; Sato T; Third Department of Internal Medicine, Kumamoto University; Medical School, Japan.
Adrenal venous sampling of blood was performed for nine patients with aldosterone-producing adenoma (APA). Measurement of adrenal venous aldosterone is useful for localization of APA but difficult, because catheterization of the right adrenal vein is not easy, and the blood is diluted by nonadrenal flow. To solve thes


CEOs: politics hurts long-term medical research.
Hospitals. 1990 Aug 20;64(16):22. Unique Identifier : AIDSLINE MED/90346367
Johnsson J
Legal questions remain in AIDS segregation cases.
Hospitals. 1990 Aug 20;64(16):59-60. Unique Identifier : AIDSLINE MED/90346381
Hudson T
HIV infection and natural killer cytotoxicity in hemophilic patients.
Immunol Lett. 1990 Jun;24(3):207-15. Unique Identifier : AIDSLINE MED/90346426
de la Barrera SS; Olabuenaga SE; Soria A; Felippo M; Perez Bianco R; de Bracco MM; Instituto de Investigaciones Hematologicas, Academia Nacional de; Medicina, Buenos Aires, Argentina.
In this study we analyzed the ability of peripheral blood mononuclear cells (PBMC) from hemophilic patients (He) with negative or positive serology for the human immunodeficiency virus (HIV), to increase natural killer (NK) cytotoxicity upon stimulation with physiological and non physiological agents. Purified interle


Human T-cell leukemia virus type-I-infected T-cell lines scarcely produce p56lck, whether or not they express lck mRNA.
Int J Cancer. 1990 Aug 15;46(2):315-9. Unique Identifier : AIDSLINE MED/90346466
Oh-Hori N; Koga Y; Yoshida H; Morita M; Kimura G; Nomoto K; Department of Immunology, Kyushu University, Fukuoka, Japan.
We have previously reported that lck mRNA (a lymphocyte-specific protein tyrosine kinase gene) is absent in human T-cell leukemia virus type I (HTLV-I)-infected interleukin-2( IL-2 )-independent T-cell lines, while HTLV-I-negative T-cell lines and HTLV-I-positive IL-2-de


Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administered.
Int J Cancer. 1990 Aug 15;46(2):337-40. Unique Identifier : AIDSLINE MED/90346470
Balzarini J; Naesens L; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.
Different treatment schedules have been investigated when evaluating the inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and 3 -azido-2 ,3 -dideoxythymidine ( AZT ) on the replication of human immunodeficiency virus type I (HIV-I) in MT-


Ion-paired high-performance liquid chromatographic separation of trimethoprim, sulfamethoxazole and N4-acetylsulfamethoxazole with solid-phase extraction.
J Chromatogr. 1990 Jun 8;528(1):235-42. Unique Identifier : AIDSLINE MED/90346977
Laizure SC; Holden CL; Stevens RC; Memphis Neurosciences Center, Methodist Hospital, TN.
Fluconazole [see comments]
J Infect. 1990 Jul;21(1):1-6. Unique Identifier : AIDSLINE MED/90347225
Hay RJ
Low-dose alternate-day pyrimethamine for maintenance therapy in cerebral toxoplasmosis complicating AIDS [letter]
J Infect. 1990 Jul;21(1):119-20. Unique Identifier : AIDSLINE MED/90347230
Bhatti N; Larson E
Anticardiolipin antibodies and Pneumocystis carinii pneumonia in patients with AIDS [letter; comment]
J Infect. 1990 Jul;21(1):120. Unique Identifier : AIDSLINE MED/90347231
Coll J; Yazbeck H; Garces JM; Berges A; Prats F; Rubies-Prat J
Ileal and jejunal absorptive function in patients with AIDS and enterococcidial infection.
J Infect. 1990 Jul;21(1):43-53. Unique Identifier : AIDSLINE MED/90347234
Kapembwa MS; Bridges C; Joseph AE; Fleming SC; Batman P; Griffin GE; Department of Communicable Diseases, St. George's Hospital; Medical School, London, U.K.
Small intestinal absorptive function was investigated in six patients with the acquired immunodeficiency syndrome (AIDS) who had diarrhoea and weight loss. Proximal function was assessed by [14C]Triolein test of fat absorption. Distal function was determined by a test of bile acid absorption in which the loss of radio


Isolation of Protomonas extorquens (the 'red phantom') from a patient with AIDS.
J Infect. 1990 Jul;21(1):87-93. Unique Identifier : AIDSLINE MED/90347241
Holton J; Miller R; Furst V; Malnick H; Department of Microbiology, University College and Middlesex; School of Medicine, London, UK.
We report the isolation of a pigmented, slowly growing, environmental organism with pink colonies from the blood of a patient with AIDS. The organism was characterised biochemically and by protein fingerprinting as Protomonas extorquens biovar 3. This is the first report of isolation of this organism from a patient


Terminal nucleotides of the preintegrative linear form of HIV-1 DNA deduced from the sequence of circular DNA junctions.
J Acquir Immune Defic Syndr. 1990;3(9):852-8. Unique Identifier : AIDSLINE MED/90347668
Kulkosky J; Katz RA; Skalka AM; Fox Chase Cancer Center, Institute for Cancer Research,; Philadelphia, PA 19111.
The termini of integrated retroviral DNAs are characterized by highly conserved dinucleotide sequences: 5 TG...//...CA3 . For the avian and murine C-type retroviruses, the dinucleotide sequences reside two deoxynucleotides (usually AA and TT) from the LTR ends of unintegrated viral DNA (5 AATG...//...CATT3 ). The num


Zidovudine therapy in an inner city population.
J Acquir Immune Defic Syndr. 1990;3(9):877-83. Unique Identifier : AIDSLINE MED/90347671
Samuels JE; Hendrix J; Hilton M; Marantz PR; Sloan V; Small CB; Division of Infectious Diseases, North Central Bronx Hospital,; New York 10467.
To determine the compliance and tolerance with zidovudine (azidothymidine or AZT ) therapy among poor, minority, and intravenous drug-using patients, data were collected on all AIDS and ARC patients followed for at least 4 weeks in a New York City Huma


Ribavirin: a role in HIV infection? [comment] [see comments]
J Acquir Immune Defic Syndr. 1990;3(9):893-5. Unique Identifier : AIDSLINE MED/90347673
Bodsworth N; Cooper DA; National Centre in HIV Epidemiology and Clinical Research,; Faculty of Medicine, University of New South Wales, Sydney,; Australia.
Effects of the use of AZT on the medical care costs of persons with AIDS in the first 12 months.
J Acquir Immune Defic Syndr. 1990;3(9):904-12. Unique Identifier : AIDSLINE MED/90347675
Scitovsky AA; Cline MW; Abrams DI; Palo Alto Medical Foundation/Research Institute, California; 94301.
It is important in planning to meet resource needs and financing of care of people with acquired immune deficiency syndrome (AIDS) to determine the effect of the use of azidothymidine ( AZT ) on overall medical care costs. This study compares the medica


Epidemiology of HIV infection among prostitutes in the Philippines.
J Acquir Immune Defic Syndr. 1990;3(9):913-20. Unique Identifier : AIDSLINE MED/90347676
Hayes CG; Manaloto CR; Basaca-Sevilla V; Padre LP; Laughlin LW; O'Rourke TF; Espinosa GE; Andrada AB; Mejia P; Cano D; U.S. Naval Medical Research Unit No. 2, Manila, Philippines.
Between 1985 and 1987, examinations for human immune deficiency virus (HIV) antibody were done on 25,392 prostitutes working in 64 cities throughout the Philippines . The country-wide seropositivity rate among prostitutes based on this sample was 0.8/1,000. Of the HIV cases, 85


Impact of AIDS on mortality in San Francisco, 1979-1986 [published erratum appears in J Acquir Immune Defic Syndr 1991;4(4):450]
J Acquir Immune Defic Syndr. 1990;3(9):921-4. Unique Identifier : AIDSLINE MED/90347677
Saunders LD; Rutherford GW; Lemp GF; Barnhart JL; Department of Health Services Administration, University of; Alberta, Edmonton, Canada.
We used death certificate data for San Francisco residents from 1979 to 1986 to calculate the number of deaths and years of potential life lost before age 65 (YPLL) for leading causes of death. Acquired immune deficiency syndrome (AIDS)-related deaths were defined as including cytomega


Vancomycin and neutropenia in AZT-treated AIDS patients with staphylococcal infections [letter]
J Acquir Immune Defic Syndr. 1990;3(9):925-6. Unique Identifier : AIDSLINE MED/90347678
Kitchen LW; Clark RA; Hanna BJ; Pollock B; Valainis GT
Acute seroconversion to HIV in a male prostitute as a consequence of occupational exposure [letter]
J Acquir Immune Defic Syndr. 1990;3(9):926-7. Unique Identifier : AIDSLINE MED/90347679
Hillman RJ; Tomlinson D; Taylor-Robinson D
One case of HIV-2 AIDS with neurological manifestations [letter]
J Acquir Immune Defic Syndr. 1990;3(9):927-8. Unique Identifier : AIDSLINE MED/90347680
Livrozet JM; Ninet J; Vighetto A; Touraine JL; Touraine F; Caudie C; Kindbeiter K; Poly H
Kaposi's sarcoma in people with AIDS from an area in southern Europe [letter]
J Acquir Immune Defic Syndr. 1990;3(9):929-30. Unique Identifier : AIDSLINE MED/90347681
Casabona J; Salas T; Lacasa C; Melbye M; Segura A
Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells.
J Virol. 1990 Sep;64(9):4093-8. Unique Identifier : AIDSLINE MED/90347799
Guatelli JC; Gingeras TR; Richman DD; Department of Medicine, University of California, San Diego.
The utilization of alternative splice acceptors for excision of the 5 major intron of human immunodeficiency virus type 1 RNA was observed after infection in vitro. Specific splice events were monitored by a cDNA-polymerase chain reaction. These splice events shared a common splice donor but utilized several alternat


Simian immunodeficiency virus displays complex patterns of RNA splicing.
J Virol. 1990 Sep;64(9):4207-16. Unique Identifier : AIDSLINE MED/90347813
Viglianti GA; Sharma PL; Mullins JI; Department of Cancer Biology, Harvard University School of Public; Health, Boston, Massachusetts 02115.
The human and simian immunodeficiency viruses encode at least six gene products that apparently serve regulatory functions. To evaluate the regulation of simian immunodeficiency virus gene expression at the level of RNA splicing, we used the polymerase chain reaction to amplify and clone cDNAs corresponding to a large


Infection of nonlymphoid cells by human immunodeficiency virus type 1 or type 2.
J Virol. 1990 Sep;64(9):4226-31. Unique Identifier : AIDSLINE MED/90347815
Ikeuchi K; Kim S; Byrn RA; Goldring SR; Groopman JE; Division of Hematology/Oncology, New England Deaconess Hospital,; Boston, Massachusetts.
Human epithelial cells (L132) derived from embryonic lung and human lung fibroblasts (MRC5) were infected by human immunodeficiency virus type 1 (HIV-1) or type 2 (HIV-2). Surface CD4 protein was detected on these cells, and recombinant soluble CD4 (sCD4) blocked infection, indicating that HIV infection was mediated b


Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation.
J Virol. 1990 Sep;64(9):4390-8. Unique Identifier : AIDSLINE GENBANK/M65024
Cheng-Mayer C; Quiroga M; Tung JW; Dina D; Levy JA; Cancer Research Institute, University of California, San; Francisco 94143.
The genome of the human immunodeficiency virus type 1 (HIV-1) is highly heterogeneous. Some of this genomic variability is reflected in the biologic and serologic differences observed among various strains of HIV-1. To map the viral determinants that correlate with pathogenicity of the virus, recombinant viruses were


Characterization and expression of novel singly spliced RNA species of human immunodeficiency virus type 1.
J Virol. 1990 Sep;64(9):4585-8. Unique Identifier : AIDSLINE MED/90347862
Arrigo SJ; Weitsman S; Zack JA; Chen IS; Department of Microbiology and Immunology, UCLA School of; Medicine.
Human immunodeficiency virus type 1 (HIV-1) expresses the Vif, Vpr, Vpu, and Env proteins through complex differential splicing of a single full-length RNA precursor. We used HIV-1-specific oligonucleotide primer pairs in a quantitative polymerase chain reaction procedure on RNA from fresh peripheral blood lymphocytes


From the Centers for Disease Control. Possible transmission of human immunodeficiency virus to a patient during an invasive dental procedure.
JAMA. 1990 Sep 5;264(9):1092-3. Unique Identifier : AIDSLINE MED/90347872
AIDS projections: how Farr out? [letter; comment]
JAMA. 1990 Sep 5;264(9):1103-4. Unique Identifier : AIDSLINE MED/90347875
Artzrouni M
Risks of HIV exposure to medical students and health care personnel [editorial]
JAMA. 1990 Sep 5;264(9):1187. Unique Identifier : AIDSLINE MED/90347893
Hermann RC
Percutaneous exposure of medical students to HIV.
JAMA. 1990 Sep 5;264(9):1188, 1190. Unique Identifier : AIDSLINE MED/90347894
Jones DB; Cornell University Medical College.
A preliminary survey of 42 fourth-year medical students at Cornell University Medical College found that 21% of the students (95% confidence interval, 9% to 34%) reported being stuck by an HIV-contaminated needle during the third and fourth years of medical school. Seventy-four percent believed their school had not ad


Minimizing risks for occupational blood-borne infections.
JAMA. 1990 Sep 5;264(9):1189, 1190. Unique Identifier : AIDSLINE MED/90347895
Fahey BJ; Henderson DK; Warren G. Magnuson Clinical Center, National Institutes of; Health.
Don't stick me, but don't take all day.
JAMA. 1990 Sep 5;264(9):1191. Unique Identifier : AIDSLINE MED/90347896
A comparison of hospital and community case management programs for persons with AIDS.
Med Care. 1990 Aug;28(8):746-55. Unique Identifier : AIDSLINE MED/90348414
Piette J; Fleishman JA; Mor V; Dill A; Center for Gerontology and Health Care Research, Brown; University, Providence, RI 02912.
To determine whether locus of AIDS case management affects the content of this service, a survey of case managers in 42 major American cities was conducted. One hundred seventy-one case managers working in both public hospitals and community-based organizations (CBOs) responded. Hospital case managers were substantial


[Good response to azidothymidine in 3 patients with vacuolar myelopathy]
Med Clin (Barc). 1990 May 5;94(17):664-5. Unique Identifier : AIDSLINE MED/90348421
von Wichmann MA; Iribarren JA; Arrizabalaga J; Bernardo P; Garde C; Rodriguez-Arrondo FJ; Unidad de Enfermedades infecciosas, Hospital Nuestra Senora de; Aranzazu, San Sebastian.
We report 3 drug abusers with human immunodeficiency virus (HIV) infection who had presented with myelopathic symptoms. A diagnosis of vacuolar myelopathy associated with HIV was made. The patients had a favorable response to azidothymidine. They were followed up as outpatients, and they showed a significant clinical


[malnutrition and human immunodeficiency virus (HIV) in Bagui (Central Africa). Study and 2-year follow-up of a cohort of 175 malnourished children and 101 mothers]
Med Trop (Mars). 1990 Apr;50(2):161-5. Unique Identifier : AIDSLINE MED/90348449
Lesbordes JL; Coulaud B; Georges AJ; Hopitaux des Armees, Toulouse, France.
In Bangui ( Central African Republic ) a survey started in 1986 for 2 years. 175 undernourished children and the mothers were surveyed. In this target group, a high seroprevalence to HIV was determined (12 p.c. of the undernourished children and 25 p.c. for the mother


[The incidence of atypical pulmonary mycobacterium infections in Reunion before the era of acquired immunodeficiency syndrome (AIDS)]
Med Trop (Mars). 1990 Apr;50(2):185-9. Unique Identifier : AIDSLINE MED/90348453
Menard O; Tanguy B; Desnanot J; Ahmed Z; Service de Pneumologie A, Hopital Villemin, Nancy.
The authors analyzed cases of pulmonary non-tuberculous mycobacterial infection observed in the Reunion Island between 1979 and 1986, before any reported case of AIDS in the Island. Isolation of non tuberculous mycobacteria from bro


AIDS programme faces donor fatigue [news]
Nature. 1990 Aug 16;346(6285):595. Unique Identifier : AIDSLINE MED/90348944
Ewing T
[Treatment with doxycycline and nifuroxazide of Isospora belli infection in AIDS]
Pathol Biol (Paris). 1990 Jun;38(5 ( Pt 2)):589-91. Unique Identifier : AIDSLINE MED/90349357
Meyohas MC; Capella F; Poirot JL; Lecomte I; Binet D; Eliaszewicz M; Frottier J; Service des Maladies Infectieuses et Tropicales, Hopital; Saint-Antoine, Paris.
Isospora belli infection is the most frequent coccidiosis after cryptosporidiosis in AIDS patients. Chronic watery diarrhea is observed. Trimethoprim-sulfamethoxazole is the recommended treatment. Four AIDS patients were intolerant to this drug and were treated with doxycycline and nifuroxazide. Three patients were cu


Psychiatric nurses' needs for AIDS information.
Perspect Psychiatr Care. 1990;25(3-4):3-9. Unique Identifier : AIDSLINE MED/90349435
Flaskerud JH
The purpose of this study was to identify 1) the needs of psychiatric nurses for information on AIDS; 2) the groups to whom they provide AIDS education, counseling, and referrals; and 3) their preferred resources for AIDS information. A national survey of 233 psychiatric nurses was conducted. The most important areas


HIV testing leaflets will come in ten languages.
Nurs Times. 1990 Aug 15-21;86(33):7. Unique Identifier : AIDSLINE MED/90349483
Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.
Proc Natl Acad Sci U S A. 1990 Aug;87(16):6058-62. Unique Identifier : AIDSLINE MED/90349554
Schnittman SM; Lane HC; Greenhouse J; Justement JS; Baseler M; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.
CD4+ T cells of patients with AIDS exhibit a qualitative defect in their ability to respond to soluble antigen while their responses to mitogens remain normal. CD4+ T cells can be broadly divided phenotypically into naive [CD45RA+ (2H4+)] and memory [CD29+ (4B4+) or CD45RO+ (UCHL1+)] cell subpopulations, which represe


Perceived consequences of employing AIDS victims: development and validation of a scale.
Psychol Rep. 1990 Jun;66(3 Pt 2):1367-74. Unique Identifier : AIDSLINE MED/90349822
Vest MJ; O'Brien FP; Vest JM; Department of Management, University of Southern Mississippi,; Hattiesburg 39406.
Preliminary results in the development of a 15-item scale to measure managers beliefs about the consequences of employing AIDS victims are reported. Study participants included 248 managers in southeastern U.S. manufacturing, government, and service organizations. Principal components analysis of the proposed scale y


Miliary tuberculosis: epidemiology, clinical manifestations, diagnosis, and outcome [see comments]
Rev Infect Dis. 1990 Jul-Aug;12(4):583-90. Unique Identifier : AIDSLINE MED/90349951
Kim JH; Langston AA; Gallis HA; Department of Medicine, Duke University Medical Center, Durham,; North Carolina.
During the early 1970s, attention was called to the changing demographics and poor prognosis of patients with miliary tuberculosis. Thirty-eight non-AIDS patients with miliary tuberculosis seen since 1975 are reviewed. Their average age was 60 years. Two-thirds of the patients had comorbid conditions. Presenting sympt


Resolution of acute renal failure in toxoplasmic encephalitis despite continuance of sulfadiazine.
Rev Infect Dis. 1990 Jul-Aug;12(4):618-20. Unique Identifier : AIDSLINE MED/90349955
Oster S; Hutchison F; McCabe R; Medical Service, Martinez Veterans Administration Medical Center,; Martinez, California.
A patient with AIDS and toxoplasmic encephalitis treated with pyrimethamine and sulfadiazine became hypovolemic and developed acute renal failure. Diagnostic sulfadiazine crystals were abundant in the urine, and ultrasound examination demonstrated sludge and stones, presumably due to sulfadiazine. Renal failure resolv


AIDS patients: smaller is costlier.
RN. 1990 Aug;53(8):13-4. Unique Identifier : AIDSLINE MED/90350009
Parasitic and other infections in AIDS. Proceedings of a meeting of the Royal Society of Tropical Medicine and Hygiene and the British Society for Parasitology. 27 June 1989.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:1-39. Unique Identifier : AIDSLINE MED/90350165
[The penetration of HIV into the population of Moscow homosexuals and its spread]
Zh Mikrobiol Epidemiol Immunobiol. 1990 May;(5):18-22. Unique Identifier : AIDSLINE MED/90350396
Pokrovskii VV; Eramova IIu
The article deals with the epidemiological investigation of cases of HIV infection among the population of homosexuals. 119 representatives of this population were checked in their sexual contacts; of these, 13 persons proved to be infected with HIV. HIV infection was found to penetrate into the homosexual population


The relationship of cocaine use to syphilis and human immunodeficiency virus infections among inner city parturient women.
Am J Obstet Gynecol. 1990 Aug;163(2):521-6. Unique Identifier : AIDSLINE MED/90350708
Minkoff HL; McCalla S; Delke I; Stevens R; Salwen M; Feldman J; Department of Obstetrics and Gynecology, State University of New; York Health Science Center, Brooklyn 11203-2098.
To study the relationship of cocaine use to syphilis and human immunodeficiency virus infections a blinded urine and serum survey was performed among parturient women at an inner city hospital. Discarded urine samples of 1206 parturient women were saved and given code numbers that were also assigned to data sheets con


Small intestinal injury and parasitic diseases in AIDS [see comments]
Ann Intern Med. 1990 Sep 15;113(6):444-9. Unique Identifier : AIDSLINE MED/90351056
Kotler DP; Francisco A; Clayton F; Scholes JV; Orenstein JM; St. Luke's-Roosevelt Hospital Center, College of Physicians and; Surgeons, Columbia University, New York, New York.
OBJECTIVES: To examine jejunal biopsies from patients with the acquired immunodeficiency syndrome (AIDS), chronic diarrhea, and weight loss, and to correlate the presence of small intestinal injury with pathogens, histopathologic changes, and absorption. DESIGN: Prospective analysis of jejunal biopsies from 43 patient


Partner notification [letter; comment]
Ann Intern Med. 1990 Sep 15;113(6):480-1. Unique Identifier : AIDSLINE MED/90351063
Comparative toxicities of amphotericin B and its monomethyl ester derivative on glial cells in culture.
Antimicrob Agents Chemother. 1990 Jul;34(7):1360-5. Unique Identifier : AIDSLINE MED/90351124
Racis SP; Plescia OJ; Geller HM; Schaffner CP; Waksman Institute of Microbiology, Rutgers, State University of; New Jersey, New Brunswick 08903.
Amphotericin B (AmB) is a potent antifungal polyene macrolide antibiotic and is the drug of choice for the treatment of deep-seated mycotic infections. Its use is limited, owing to its nephrotoxicity, and it must be dispersed in deoxycholate for parenteral administration. In contrast, AME (the monomethyl derivative ofh


Comparison of in vitro antimicrobial susceptibilities of Mycobacterium avium-M. intracellulare strains from patients with acquired immunodeficiency syndrome (AIDS), patients without AIDS, and animal sources.
Antimicrob Agents Chemother. 1990 Jul;34(7):1390-2. Unique Identifier : AIDSLINE MED/90351130
Byrne SK; Geddes GL; Isaac-Renton JL; Black WA; British Columbia Centre for Disease Control, Division of; Laboratories, Ministry of Health, Vancouver, Canada.
Difloxacin, A-56620, cefazolin, cefotaxime, ceftizoxime, cephapirin, SK&F 88070, and spectinomycin were used to compare the in vitro susceptibilities of Mycobacterium avium-M. intracellular isolates from patients with acquired immunodeficiency syndrome (AIDS), patients without AIDS, and diseased animals. Against th


Effect of dipyridamole on transport and phosphorylation of thymidine and 3'-azido-3'-deoxythymidine in human monocyte/macrophages.
Biochem Pharmacol. 1990 Aug 15;40(4):867-70. Unique Identifier : AIDSLINE MED/90351513
Betageri GV; Szebeni J; Hung K; Patel SS; Wahl LM; Corcoran M; Weinstein JN; National Cancer Institute, National Institutes of Health,; Bethesda, MD 20892.
Dipyridamole (DPM), a commonly used coronary vasodilator and antithrombotic drug, was shown recently to potentiate the antiviral effect of 3 -azido-3 -deoxythymidine ( AZT ) in HIV-1 infected human monocyte-derived macrophages (M/M) in vitro. We report


Central nervous system toxoplasmosis in AIDS patients: efficacy of an intermittent maintenance therapy.
AIDS. 1990 Jun;4(6):511-7. Unique Identifier : AIDSLINE MED/90351563
Pedrol E; Gonzalez-Clemente JM; Gatell JM; Mallolas J; Miro JM; Graus F; Alvarez R; Mercader JM; Berenguer J; Jimenez de Anta MT; et al; Infectious Disease Unit, Hospital Clinic, Barcelona, Spain.
Fifty-five episodes of central nervous system (CNS) toxoplasmosis developing in 43 of the 329 AIDS cases seen at our institution were diagnosed during a 34-month period and were prospectively studied. Acute episodes were treated with a pyrimethamine/sulfadiazine (P/S) combination for a mean of 21 days. Because of a pr


Toxoplasma gondii serology in HIV-infected patients: the development of central nervous system toxoplasmosis in AIDS.
AIDS. 1990 Jun;4(6):519-21. Unique Identifier : AIDSLINE MED/90351564
Grant IH; Gold JW; Rosenblum M; Niedzwiecki D; Armstrong D; Division of Infectious Disease, Memorial Sloan-Kettering Cancer; Center, New York, NY 10021.
Central nervous system (CNS) toxoplasmosis is an important infectious complication of AIDS which requires prolonged treatment. Most cases occur in patients with serologic evidence of prior exposure and therefore appear to result from reactivation of a previously acquired infection. Antibody to Toxoplasma gondii was fo


A prospective comparison of neuropsychologic function in HIV-seropositive and seronegative methadone-maintained patients.
AIDS. 1990 Jun;4(6):565-9. Unique Identifier : AIDSLINE MED/90351571
McKegney FP; O'Dowd MA; Feiner C; Selwyn P; Drucker E; Friedland GH; Department of Psychiatry, Albert Einstein College of Medicine,; Montefiore Medical Center, Bronx, New York.
A prospective longitudinal study of neuropsychological and psychosocial functioning in a methadone-maintained population was initiated to test the hypothesis that cognitive impairments may be present early in the course of HIV infection, before the onset of other physical symptoms. A total of 220 methadone-clinic pati


Prevention of transfusion-associated HIV transmission in Kinshasa, Zaire: HIV screening is not enough.
AIDS. 1990 Jun;4(6):571-4. Unique Identifier : AIDSLINE MED/90351572
Jager H; N'Galy B; Perriens J; Nseka K; Davachi F; Kabeya CM; Rauhaus G; Peyerl G; Ryder RW; Rehle T; Deutsche Gesellschaft fur Technische Zusammenarbeit, (GTZ) GmbH,; Eschborn, FRG.
The purpose of this study was to develop a strategy to reduce transfusion-related HIV transmission which went beyond the limits of routine HIV screening of blood donors. Current blood transfusion practices were assessed in 1044 patients for whom staff physicians had requested a transfusion between 5 September and 19 O


Shorter size of transmembrane glycoprotein of an HIV-1 isolate.
AIDS. 1990 Jun;4(6):575-6. Unique Identifier : AIDSLINE MED/90351573
Shimizu H; Morikawa S; Yamaguchi K; Tsuchie H; Hachimori K; Ushijima H; Kitamura T; Division of AIDS Virus, National Institute of Health, Tokyo,; Japan.
An HIV-1 strain carrying a shorter form of the transmembrane glycoprotein (TM) with a mobility of 32 kD, named KB-1, was isolated from a Japanese male hemophiliac by coculture of his peripheral blood mononuclear cells (PBMCs) with MT-2 cells and adaption to TALL-1 cells. Another HIV-1 strain, named KB-2, was isolated


Many people who seek anonymous HIV-antibody testing would avoid it under other circumstances.
AIDS. 1990 Jun;4(6):585-8. Unique Identifier : AIDSLINE MED/90351576
Kegeles SM; Catania JA; Coates TJ; Pollack LM; Lo B; Center for AIDS Prevention Studies, University of California, San; Francisco 94143.
Decreases in high-risk behavior have been observed when people have sought anonymous or confidential HIV-antibody testing accompanied by counseling. HIV-antibody testing also benefits those who are tested, since people who find that they are seropositive can receive closer medical follow-up, and, in certain cases, med


Myelopathy and HIV infection.
AIDS. 1990 Jun;4(6):589-91. Unique Identifier : AIDSLINE MED/90351577
Smith T; Jakobsen J; Trojaborg W; Department of Clinical Neurophysiology, Rigshospitalet,; Copenhagen, Denmark.
The clinical significance of myelopathy associated with HIV infection is poorly understood. Recently, a prospective electrophysiological follow-up study of spinal-evoked potentials in HIV-seropositive men without AIDS revealed a 32% prolongation of the latency from the gluteal crease to the 12th thoracic vertebra (T12


Toxoplasmic encephalitis.
AIDS. 1990 Jun;4(6):593-5. Unique Identifier : AIDSLINE MED/90351578
Luft BJ; Hafner R; Department of Medicine, SUNY, Stony Brook 11794.
French public opinion regarding the diversification of retail outlets for condoms [letter] [published erratum appears in AIDS 1990 Oct;4(10):following A58]
AIDS. 1990 Jun;4(6):597-8. Unique Identifier : AIDSLINE MED/90351579
Spencer BE; Spira A
Incidence of acute hepatitis B in injecting drug users as an indicator of continuing HIV transmission--international implications [letter]
AIDS. 1990 Jun;4(6):598-9. Unique Identifier : AIDSLINE MED/90351580
Mele A; Rezza G; Stazi MA; Gill ON; Pasquini P
HIV infection and intestinal pseudo-obstruction [letter]
AIDS. 1990 Jun;4(6):599-601. Unique Identifier : AIDSLINE MED/90351581
Victorino RM; Lucas M; Neto F; de Moura MC
The presentation of adult HIV-1 disease in Kampala hospitals [letter]
AIDS. 1990 Jun;4(6):601-2. Unique Identifier : AIDSLINE MED/90351582
Muller O; Musoke P; Okong P; Duggan M; Moser R
Changes in knowledge, attitudes, and behavior as a result of a community-based AIDS prevention program.
AIDS Educ Prev. 1990 Spring;2(1):12-23. Unique Identifier : AIDSLINE MED/90351743
Miller TE; Booraem C; Flowers JV; Iversen AE; Chapman College, Orange, CA 92666.
The study evaluates the outcome of a California-based AIDS prevention program, Stop AIDS. Community discussion groups focusing on information, attitudes, and behavior associated with HIV infection and transmission were conducted in one-time, 3 1/2-hour sessions. Participants completed different versions of the AIDS Pr


A skills-training group intervention model to assist persons in reducing risk behaviors for HIV infection.
AIDS Educ Prev. 1990 Spring;2(1):24-35. Unique Identifier : AIDSLINE MED/90351744
Kelly JA; St. Lawrence JS; Betts R; Brasfield TL; Hood HV; Department of Psychiatry and Human Behavior, University of; Mississippi Medical Center, Jackson 39216.
Fifteen gay men with a history of recent high-risk sexual activities attended seven group sessions that provided risk education, training in self-management skills pertinent to risk reduction, sexual assertiveness training, and problem solving with respect to health consciousness, social supports, and efficacy of risk


A cross-sectional analysis of variables impacting on AIDS-related knowledge, attitudes, and behaviors among employees of a Minnesota teaching hospital.
AIDS Educ Prev. 1990 Spring;2(1):36-47. Unique Identifier : AIDSLINE MED/90351745
Henry K; Campbell S; Willenbring K; Section of Infectious Diseases, St. Paul-Ramsey Medical Center,; St. Paul, MN 55101.
We examined variables that were correlated with the AIDS-related knowledge, attitudes, and behaviors among employees of a 455-bed acute-care Minnesota teaching hospital and its associated clinics, located in a low-prevalence area for HIV infection. In August 1987, an anonymous questionnaire was sent via interdepartmen


Knowledge and attitudes about AIDS among first- and second-year medical students.
AIDS Educ Prev. 1990 Spring;2(1):48-57. Unique Identifier : AIDSLINE MED/90351746
Johnson JA; Campbell AE; Toewe CH 2d; Bell BJ; Department of Family and Community Medicine, Eastern Virginia; Medical School, Norfolk 23501.
Several studies have concluded that many physicians may harbor fearful and prejudicial attitudes toward AIDS patients and may lack the skills necessary to respond to the growing number of patients with AIDS. The authors surveyed 73 preclinical medical students at Eastern Virginia Medical School of the Medical College


Evaluating the outcomes of AIDS education.
AIDS Educ Prev. 1990 Spring;2(1):70-83. Unique Identifier : AIDSLINE MED/90351748
Bell RA; Feldmann TB; Grissom S; Purifoy FE; Stephenson JJ; Deines H; Frierson R; Gould A; Hunt L; Hyde J; et al; Department of Psychiatry and Behavioral Sciences, University of; Louisville School of Medicine, KY 40292.
AIDS provides a unique challenge to health educators, requiring continuous evaluation and modification of educational strategies. Pretest and posttest questionnaires were thus used to assess the outcomes of AIDS training sessions. Results show that hour-long sessions result in knowledge acquisition and increased confi


Fighting AIDS on the streets [news]
AIDS Educ Prev. 1990 Spring;2(1):84-5. Unique Identifier : AIDSLINE MED/90351749
Mason R
WHO partnership grants for non-governmental activities on AIDS [news]
AIDS Educ Prev. 1990 Spring;2(1):86-7. Unique Identifier : AIDSLINE MED/90351750
Grose R
NCIH AIDS project and NGOs [news]
AIDS Educ Prev. 1990 Spring;2(1):87-8. Unique Identifier : AIDSLINE MED/90351751
Igras S
Acquired immunodeficiency syndrome (AIDS)--data as at 31 December 1989.
Wkly Epidemiol Rec. 1990 Jan 5;65(1):1-2. Unique Identifier : AIDSLINE MED/90352068
Acquired immunodeficiency syndrome (AIDS) in 1989.
Wkly Epidemiol Rec. 1990 Mar 23;65(12):85-8. Unique Identifier : AIDSLINE MED/90352076
Acquired immunodeficiency syndrome (AIDS). Surveillance update to 31 December 1989 in the WHO European Region and projections up to 1991.
Wkly Epidemiol Rec. 1990 Apr 20;65(16):117-20. Unique Identifier : AIDSLINE MED/90352089
Acquired immunodeficiency syndrome (AIDS)--data as at 30 April 1990.
Wkly Epidemiol Rec. 1990 May 4;65(18):133-4. Unique Identifier : AIDSLINE MED/90352095
Acquired immunodeficiency syndrome (AIDS)--data as at 31 May 1990.
Wkly Epidemiol Rec. 1990 Jun 1;65(22):165-6. Unique Identifier : AIDSLINE MED/90352110
Acquired immunodeficiency syndrome (AIDS)--data as at 30 June 1990.
Wkly Epidemiol Rec. 1990 Jul 6;65(27):205-6. Unique Identifier : AIDSLINE MED/90352124
Acquired immunodeficiency syndrome (AIDS)--data as at 31 January 1990.
Wkly Epidemiol Rec. 1990 Feb 2;65(5):29-30. Unique Identifier : AIDSLINE MED/90352135
Acquired immunodeficiency syndrome (AIDS). Surveillance update to 30 September 1989 in the WHO European Region.
Wkly Epidemiol Rec. 1990 Feb 2;65(5):31-4. Unique Identifier : AIDSLINE MED/90352136
Acquired immunodeficiency syndrome (AIDS).
Wkly Epidemiol Rec. 1990 Feb 23;65(8):56-7. Unique Identifier : AIDSLINE MED/90352144
Virus diseases. Public health implications of HTLV-I in the Caribbean.
Wkly Epidemiol Rec. 1990 Mar 2;65(9):63-5. Unique Identifier : AIDSLINE MED/90352145
Depsipeptide analogues of elastin repeating sequences: conformational analysis.
Biopolymers. 1990 Oct-Nov;29(12-13):1652-68. Unique Identifier : AIDSLINE MED/90352344
Arad O; Goodman M; Chemistry Department, University of California, San Diego, La; Jolla 92093.
In this work the effect of elimination of a specific hydrogen bond on the conformation of the repeating peptides of elastin was studied. These repeating sequences are the pentapeptide Val-Pro-Gly-Val-Gly and the hexapeptide Val-Ala-Pro-Gly-Val-Gly. These sequences have been proposed to occur in a beta-turn conformatio


Kaposi's sarcoma in patients with acquired immune deficiency syndrome. A flow cytometric DNA analysis of 26 lesions in 21 patients.
Cancer. 1990 Aug 15;66(4):758-64. Unique Identifier : AIDSLINE MED/90352507
Fukunaga M; Silverberg SG; Department of Pathology, George Washington University Medical; Center, Washington, D.C. 20037.
The DNA content of formalin-fixed, paraffin-embedded tissue from 21 patients (26 lesions) with Kaposi s sarcoma associated with acquired immune deficiency syndrome (AIDS) was analyzed by flow cytometry. The lesions were classified histologically into the following three types according to the predominant pattern: gran


Hodgkin's disease after non-Hodgkin's malignant lymphoma in acquired immune deficiency syndrome.
Cancer. 1990 Sep 1;66(5):960-4. Unique Identifier : AIDSLINE MED/90352542
Senaldi E; Lee MH; Toth I; Grace W; Department of Pathology, St. Vincent's Hospital and Medical; Center, New York, NY 10011.
Hodgkin s disease (HD) after treatment of non-Hodgkin s lymphoma (NHL) has been reported but is extremely rare, and to the authors knowledge has not been reported in patients with acquired immune deficiency syndrome (AIDS). The authors present a case of an AIDS patient who develop


Augmentation of cytotoxic effect of tumor necrosis factor on human immunodeficiency virus-infected cells by staurosporine, a potent protein kinase C inhibitor.
Cancer Res. 1990 Sep 1;50(17):5287-90. Unique Identifier : AIDSLINE MED/90352563
Hamamoto Y; Matsuyama T; Yamamoto N; Kobayashi N; Department of Virology and Parasitology, Yamaguchi University; School of Medicine, Japan.
We have examined the effect of the protein kinase C (PKC) inhibitor, staurosporine, on tumor necrosis factor (TNF)-induced cytotoxic action and augmentation of human immunodeficiency virus (HIV) expression on the chronically HIV-infected T-cell line, MOLT-4/HIV (HTLV-IIIB strain). Staurosporine enhanced the decrease i


Studies with canine sera that contain antibodies which recognize human immunodeficiency virus structural proteins.
Cancer Res. 1990 Sep 1;50(17 Suppl):5628S-5630S. Unique Identifier : AIDSLINE MED/90352614
Strandstrom HV; Higgins JR; Mossie K; Theilen GH; College of Veterinary Medicine, Helsinki, Finland.
In a serological survey, using the immunoblotting technique, we found that substantial numbers of dog sera from both normal and diseased dogs, including dogs with neoplasia, reacted with one or more human immunodeficiency virus (HIV) recombinant proteins. A total of 144 dog sera were tested, and 72 (50%) of them react


Species tropism of HIV-1 infectivity of interspecific cell hybridomas implies non-CD4 structures are required for cell entry.
Cancer Detect Prev. 1990;14(3):317-20. Unique Identifier : AIDSLINE MED/90352630
Weiner DB; Hubner K; Williams WV; Greene MI; University of Pennsylvania, Philadelphia 19104-6082.
Studies have demonstrated that CD4 may be necessary but not sufficient for human immunodeficiency virus (HIV) infection. Murine cell lines constructed to express the human CD4 glycoprotein demonstrate a restriction in their ability to support infection by the HIV-1 retrovirus. Such restrictions may indicate that molec


Viral immune deficiency and cancer in patients with AIDS. The acquired immunodeficiency syndrome and related neoplasms.
Cancer Detect Prev. 1990;14(3):317-413. Unique Identifier : AIDSLINE MED/90352631
Role of diagnostic lymphnode biopsies in 56 anti-HIV positive patients.
Cancer Detect Prev. 1990;14(3):353-7. Unique Identifier : AIDSLINE MED/90352638
Moresco L; Gipponi M; CaFiero F; Badellino F; Pagano G; Alessandrini A; Nicolo G; Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.
The authors have examined two separate series of samples from 33 and 23 anti-HIV positive patients with persistent generalized lymphadenopathy (PGL) undergoing lymphnode biopsy. For the first group of patients, the aim was to evaluate the diagnostic and prognostic correlation between clinical and laboratory features a


Immunoglobulin and Myc gene structure in lymphnode biopsies from HIV-positive patients with LAS and lymphoma.
Cancer Detect Prev. 1990;14(3):359-62. Unique Identifier : AIDSLINE MED/90352639
Saglio G; Foa R; Guerrasio A; di Celle PF; Palestro G; Sinicco A; Gobbi M; Gavosto F; Sezione de Clinica Medica, Departimento di Scienze Biomediche e; Oncologia Umana, Torino, Italy.
The pattern of immunoglobulin (Ig) gene rearrangement and the genomic structure of the Myc locus were investigated in the DNA of 20 lymphnode biopsies of patients suffering from lymphoadenopathy-associated syndrome (LAS) and from 3 patients with Burkitt s lymphoma. Although polyclonality was the prevalent pattern of I


Crack users: the new AIDS risk group?
Cancer Detect Prev. 1990;14(3):363-8. Unique Identifier : AIDSLINE MED/90352640
Fullilove RE; Fullilove MT; Bowser B; Gross S; Multicultural Inquiry and Research on AIDS, San Francisco, CA; 94105.
Crack cocaine, a smokable form of cocaine hydrochloride, is now widely available in American inner cities. Reports of high rates of unprotected sexual activity among crack users, coupled with reports of high rates of sexually transmitted diseases (STDs), have raised fears that this population of drug users may soon be


Bacterial and fungal infections in patients with the acquired immunodeficiency syndrome.
Cancer Detect Prev. 1990;14(3):377-81. Unique Identifier : AIDSLINE MED/90352642
Rolston KV; Radentz S; Rodriguez S; M.D. Anderson Cancer Center, Houston, TX 77030.
Over a 14-month period, 136 episodes of bacterial and 26 episodes of fungal infection were identified from the microbiology records of 444 patients with acquired immunodeficiency syndrome (AIDS). The respective rates for infection were 31 of 100 admissions (bacterial) and 5 of 100 admissions (fungal). Contributory fac


Immunoliposome targeting to CD4+ cells in human blood.
Cancer Detect Prev. 1990;14(3):383-90. Unique Identifier : AIDSLINE MED/90352643
Phillips NC; Tsoukas C; Montreal General Hospital Research Institute, Quebec, Canada.
Liposomes were prepared from phospholipid formulations recognized or ignored by cells of the reticuloendothelial system (RES+ve or RES-ve, respectively). The ability of these liposomes to interact with CD4+ve cells in purified leukocyte fractions or in whole blood has been determined. RES+ve liposomes bound to monocyt


Synchronous Hodgkin's disease and non-Hodgkin's lymphoma in an adult with acquired immunodeficiency syndrome (AIDS).
Cancer Detect Prev. 1990;14(3):395-401. Unique Identifier : AIDSLINE MED/90352645
Gallagher JG; Meschter SC; Department of Hematology/Oncology, Geisinger Medical Center,; Danville, PA 17822.
A 26-year-old male seropositive for human immunodeficiency virus (HIV) infection presented with atypical Hodgkin s disease. Subsequently, synchronous, aggressive non-Hodgkin s lymphoma was identified in this patient. Atypical Hodgkin s disease appears to be an opportunistic neoplas


Anti-cardiolipin antibodies and HIV infection.
Clin Exp Immunol. 1990 Aug;81(2):263-6. Unique Identifier : AIDSLINE MED/90352865
Maclean C; Flegg PJ; Kilpatrick DC; Blood Transfusion Centre, Royal Infirmary, Edinburgh, Scotland,; UK.
Anti-cardiolipin antibodies of IgG class were found in 48% of intravenous drug users, 38% of homosexuals and 14% of heterosexuals (with no other risk factor) infected with HIV. Anti-cardiolipin antibodies were not increased in HIV-negative heterosexual partners of HIV-infected patients, but mildly elevated levels were


Detection of HIV-specific antibodies in infancy by isoelectric focusing and affinity immunoblotting.
Dis Markers. 1990 Mar-Apr;8(2):100. Unique Identifier : AIDSLINE MED/90352910
Generation of hybrid human immunodeficiency virus by homologous recombination.
Dis Markers. 1990 Mar-Apr;8(2):101. Unique Identifier : AIDSLINE MED/90352911
Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding.
Dis Markers. 1990 Mar-Apr;8(2):101-2. Unique Identifier : AIDSLINE MED/90352912
The MHC-binding and gp120-binding functions of CD4 are separable.
Dis Markers. 1990 Mar-Apr;8(2):102-3. Unique Identifier : AIDSLINE MED/90352913
Inhibition of soluble CD4 therapy by antibodies to HIV.
Dis Markers. 1990 Mar-Apr;8(2):107-8. Unique Identifier : AIDSLINE MED/90352918
What do western blot indeterminate patterns for human immunodeficiency virus mean in EIA-negative blood donors.
Dis Markers. 1990 Mar-Apr;8(2):108. Unique Identifier : AIDSLINE MED/90352919
Small-intestinal brushing cytology in the diagnosis of cryptosporidiosis in AIDS.
Diagn Cytopathol. 1990;6(3):193-6. Unique Identifier : AIDSLINE MED/90353078
Silverman JF; Levine J; Finley JL; Larkin EW; Norris HT; Department of Clinical Pathology and Diagnostic Medicine, East; Carolina University School of Medicine, Greenville, NC 27834.
We report the cytologic findings of small intestinal brushing material showing cryptosporidiosis in two patients with acquired immunodeficiency syndrome (AIDS). Cryptosporidia measuring approximately 2-4 mu were aligned along the surface of the glandular cells, although many freely dispersed organisms were also presen


Nutritional status assessment of HIV-positive drug addicts.
Eur J Clin Nutr. 1990 May;44(5):415-8. Unique Identifier : AIDSLINE MED/90353313
Varela P; Marcos A; Ripoll S; Requejo A; Herrera P; Casas A; Departamento de Nutricion y Bromatologia, I. (Nutricion),; Facultad de Farmacia, Ciudad Universitaria, Madrid, Spain.
Since human immunodeficiency virus (HIV) is known to lead to modifications of immune function and interrelationships among malnutrition, anergy and drug addiction have been shown, the aim of this work was to assess the nutritional status of 36 male heroin addicts under a period of detoxication (3 months). They were di


Association of a particular amino acid sequence of the HLA-DR beta 1 chain with HTLV-I-associated myelopathy.
Eur J Immunol. 1990 Jul;20(7):1603-6. Unique Identifier : AIDSLINE MED/90353397
Usuku K; Nishizawa M; Matsuki K; Tokunaga K; Takahashi K; Eiraku N; Suehara M; Juji T; Osame M; Tabira T; Division of Demyelinating Disease and Aging, National Institute; of Neuroscience, National Center of Neurology and Psychiatry,; Japan.
Analyses of HLA-DRB1 gene using polymerase chain reaction and sequence-specific oligonucleotide probes reveal that the amino acid sequence Glu-Gln-Arg-Arg-Ala-Ala-Val at positions 69-75 of the third hypervariable region (HVR) of HLA-DR beta 1 chain is significantly associated with HTLV-I-associated myelopathy (HAM). S


Investigation of seemingly pathogen-negative diarrhoea in patients infected with HIV1.
Gut. 1990 Aug;31(8):886-9. Unique Identifier : AIDSLINE MED/90353798
Connolly GM; Forbes A; Gazzard BG; Department of Gastroenterology, St Stephen's Hospital, London.
Thirty three consecutive patients infected by human immunodeficiency virus type 1 (HIV1) with persistent diarrhoea which remained undiagnosed after microbiological examination of six stool samples and rectal histology were investigated for malabsorption. All had xylose and Schilling tests, distal duodenal biopsy, comp


Enteropathy associated with HIV [letter; comment]
Gut. 1990 Aug;31(8):960. Unique Identifier : AIDSLINE MED/90353819
Batman PA; Kapembwa MS; Griffin GE
Histopathology of endocervical infection caused by Chlamydia trachomatis, herpes simplex virus, Trichomonas vaginalis, and Neisseria gonorrhoeae.
Hum Pathol. 1990 Aug;21(8):831-7. Unique Identifier : AIDSLINE MED/90353932
Kiviat NB; Paavonen JA; Wolner-Hanssen P; Critchlow CW; Stamm WE; Douglas J; Eschenbach DA; Corey LA; Holmes KK; Department of Pathology, University of Washington, Seattle.
We determined the histologic correlates of clinically identified mucopurulent cervicitis, culture-proven cervical infection with Chlamydia trachomatis, Neisseria gonorrhoeae, herpes simplex virus (HSV), and vaginal infection with Trichomonas vaginalis by examining cervical biopsies from 83 women. Clinical mucopurulent


Nursing care of women with AIDS in the home care setting.
Home Healthc Nurse. 1990 Jul-Aug;8(4):15-9. Unique Identifier : AIDSLINE MED/90354247
Benedict S
Confidentiality and HIV status: accidental exposure to patient blood or bodily fluids.
Home Healthc Nurse. 1990 Jul-Aug;8(4):5-6. Unique Identifier : AIDSLINE MED/90354255
Brent NJ
Adolescents' thoughts and feelings about AIDS in relation to cognitive maturity.
J Adolesc. 1990 Jun;13(2):185-7. Unique Identifier : AIDSLINE MED/90354544
Peterson CC; Murphy L; School of Social Sciences, Murdoch University, Western Australia.
Apologies for interdiction: the homosexual question. Essay review.
J Hist Behav Sci. 1990 Jul;26(3):225-41. Unique Identifier : AIDSLINE MED/90354649
Rousseau GS
Human T lymphotropic virus type I infection in Papua New Guinea: high prevalence among the Hagahai confirmed by western analysis.
J Infect Dis. 1990 Sep;162(3):649-54. Unique Identifier : AIDSLINE MED/90354704
Yanagihara R; Jenkins CL; Alexander SS; Mora CA; Garruto RM; Laboratory of Central Nervous System Studies, National Institute; of Neurological Disorders and Stroke, National Institutes of; Health, Bethesda, Maryland 20892.
A serologic survey for human T lymphotropic virus type I (HTLV-I) infection was conducted on nearly half of the entire 260-member Hagahai population, a hunter-horticulturist group occupying the northern banks of the Yuat River Gorge in Madang Province of


Neutralization of multiple HIV-1 isolates from a single subject by autologous sequential sera.
J Infect Dis. 1990 Sep;162(3):735-7. Unique Identifier : AIDSLINE MED/90354719
Tremblay M; Wainberg MA; Lady Davis Institute, Jewish General Hospital, McGill AIDS; Centre, Montreal, Canada.
Titers of neutralizing antibodies to different strains of human immunodeficiency virus type 1 (HIV-1), including five isolates sequentially obtained from one infected subject, were determined using sequential serum samples obtained from that individual. Neutralizing antibodies were detected against the HIV-IIIB labora


Prevalence of antibodies to human immunodeficiency virus and to human T cell leukemia virus type I in transfused sickle cell disease patients.
J Infect Dis. 1990 Sep;162(3):743-5. Unique Identifier : AIDSLINE MED/90354721
Castro O; Saxinger C; Barnes S; Alexander S; Flagg R; Frederick W; Department of Medicine, Howard University College of Medicine,; Washington, DC 20059.
The prevalence of the human immunodeficiency virus (HIV) antibody and the human T cell leukemia virus type I (HTLV-I) antibody was examined in 116 adults with sickle cell disease. Eighty-eight of them had received a mean of 18.6 transfusions of red blood cells between 1978 and 1985, and none was positive for the HIV a


Failure of tuberculosis chemotherapy in a human immunodeficiency virus-infected patient [letter] [see comments]
J Infect Dis. 1990 Sep;162(3):778-9. Unique Identifier : AIDSLINE MED/90354732
Dylewski J; Thibert L
Constitutive expression of parathyroid hormone-related protein gene in human T cell leukemia virus type 1 (HTLV-1) carriers and adult T cell leukemia patients that can be trans-activated by HTLV-1 tax gene.
J Exp Med. 1990 Sep 1;172(3):759-65. Unique Identifier : AIDSLINE MED/90354777
Watanabe T; Yamaguchi K; Takatsuki K; Osame M; Yoshida M; Department of Viral Oncology, Cancer Institute, Toshima-ku,; Tokyo, Japan.
Adult T cell leukemia (ATL) is associated with human T cell leukemia virus type 1 (HTLV-1) infection, and almost all ATL patients have the complication of hypercalcemia. To understand the mechanism of the high incidence of hypercalcemia in ATL, we studied the expression of a parathyroid hormone-related protein (PTHrP)


Analysis of physical interactions between peptides and HLA molecules and application to the detection of human immunodeficiency virus 1 antigenic peptides.
J Exp Med. 1990 Sep 1;172(3):889-99. Unique Identifier : AIDSLINE MED/90354790
Choppin J; Martinon F; Gomard E; Bahraoui E; Connan F; Bouillot M; Levy JP; Institut National de la Sante et de la Recherche Medicale U152,; Hopital Cochin, Paris, France.
The physical association of 40 antigenic peptides and purified HLA class I and class II molecules was monitored using a direct peptide binding assay (PBA) in solid phase and an inhibition peptide binding assay (IPBA) in which the competing peptide was present in a soluble phase. We also examined the ability of differe


Malar rash in a patient with Reiter's syndrome--a clue for the diagnosis of human immunodeficiency virus infection.
J Rheumatol. 1990 Jun;17(6):843-5. Unique Identifier : AIDSLINE MED/90355101
Buskila D; Langevitz P; Tenenbaum J; Gladman DD; University of Toronto Rheumatic Disease Unit, Mount Sinai; Hospital, ON, Canada.
We describe a man who presented with Reiter s syndrome and a new prominent malar rash. The malar rash was the clue for the early diagnosis of human immunodeficiency virus (HIV) infection in this patient. A high index of suspicion for the diagnosis of HIV infection is required in patients with Reiter s syndrome present


A treatment crisis: cocaine use by clients in methadone maintenance programs.
J Subst Abuse Treat. 1990;7(2):101-7. Unique Identifier : AIDSLINE MED/90355270
Kolar AF; Brown BS; Weddington WW; Ball JC; Addiction Research Center of the National Institute on Drug; Abuse, Baltimore, Maryland.
We surveyed 11 methadone maintenance treatment programs in the Baltimore, Maryland, area to examine cocaine use among their 2414 clients and the methods employed to cope with that use. The percent of clients with at least one urine sample positive for cocaine during the month previous to study was 15.7% (379/2414) and


From the Food and Drug Administration.
JAMA. 1990 Sep 12;264(10):1239. Unique Identifier : AIDSLINE MED/90355362
Nightingale SL
Partner acceptance of health department notification of HIV exposure, South Carolina.
JAMA. 1990 Sep 12;264(10):1284-6. Unique Identifier : AIDSLINE MED/90355378
Jones JL; Wykoff RF; Hollis SL; Longshore ST; Gamble WB Jr; Gunn RA; Division of Field Services, Centers for Disease Control, Atlanta,; Ga.
To determine the acceptability of health department notification of sex and needle-sharing partners of persons infected with human immunodeficiency virus (HIV), we administered an anonymous questionnaire to partners notified of their exposure to HIV during the previous 2 years. Of the 202 partners notified, 132 (65%)


Problems with incentives [editorial; comment]
JAMA. 1990 Sep 12;264(10):1294-5. Unique Identifier : AIDSLINE MED/90355381
Todd JS
Porphyria cutanea tarda in human immunodeficiency virus-infected patients.
JAMA. 1990 Sep 12;264(10):1315-6. Unique Identifier : AIDSLINE MED/90355383
Cohen PR; Suarez SM; DeLeo VA; College of Physicians and Surgeons, Columbia University, New; York, NY.
Impact of HIV infection on the tuberculosis problem worldwide.
Kekkaku. 1990 Jun;65(6):429-38. Unique Identifier : AIDSLINE MED/90355482
Styblo K
Proposed standard on bloodborne pathogens summary of key provisions.
Kans Nurse. 1990 Jun-Jul;65(6):11. Unique Identifier : AIDSLINE MED/90355484
[Non-Hodgkin's lymphoma and acquired immunodeficiency syndrome (letter)]
Med Clin (Barc). 1990 May 12;94(18):718-9. Unique Identifier : AIDSLINE MED/90355587
Reparaz Padros J; Perez Equiza E; Queizan JA
[Nocardiosis in a carrier of antibodies against the human immunodeficiency virus (letter)]
Med Clin (Barc). 1990 May 12;94(18):719. Unique Identifier : AIDSLINE MED/90355588
Simeon CP; Balboa A; Tolosa C; Lu L
[HTLV-I in patients from Barcelona with connective tissue diseases, neurologic demyelinating diseases and lymphoproliferative syndromes]
Med Clin (Barc). 1990 May 19;94(19):730-2. Unique Identifier : AIDSLINE MED/90355591
Soriano V; Tor J; Ribera JM; Flores A; Casals A; Ribas-Mundo M; Unidad de Enfermedades Infecciosas, Hospital de Badalona,; Universidad Autonoma de Barcelona.
The presence of antibodies against HTLV-I was investigated with ELISA and Western blot techniques in 76 patients with lymphoproliferative syndromes (n = 53), idiopathic subacute myelopathies (n = 4), chronic T-lymphocytosis (n = 3) and collagen vascular diseases (n = 16) diagnosed in the Barcelona area. 9 HIV seroposi


[Preventive aspects in the use of serologic markers of the human immunodeficiency virus infection (editorial)]
Med Clin (Barc). 1990 May 19;94(19):733-5. Unique Identifier : AIDSLINE MED/90355592
Gonzalez Lopez E; Puche Lopez N; Unidad Docente de Medicina de Familia y Comunitaria, Centro de; Salud, Parla, Madrid.
[Absence of HTLV-I retrovirus infections in lymphoproliferative syndromes in the province of Vizcaya (letter)]
Med Clin (Barc). 1990 May 19;94(19):757-8. Unique Identifier : AIDSLINE MED/90355599
Esparaza B; Olabarria I; Garcia MV; Miguel F
Immunoassays for diagnosis of infectious diseases.
Methods Enzymol. 1990;184:529-37. Unique Identifier : AIDSLINE MED/90355910
Yolken RH
Sensitive immunoassay for human immunodeficiency viral core proteins.
Methods Enzymol. 1990;184:556-60. Unique Identifier : AIDSLINE MED/90355913
Huskins KR; Reagan KJ; Wehrly JA; Neumann JE
Familial spastic paraparesis syndrome associated with HTLV-I infection.
N Engl J Med. 1990 Sep 13;323(11):732-7. Unique Identifier : AIDSLINE MED/90356084
Salazar-Grueso EF; Holzer TJ; Gutierrez RA; Casey JM; Desai SM; Devare SG; Dawson G; Roos RP; Department of Neurology, University of Chicago, IL 60637.
Zidovudine in asymptomatic HIV infection [letter; comment]
N Engl J Med. 1990 Sep 13;323(11):754-6. Unique Identifier : AIDSLINE MED/90356089
Fast track for AIDS and cancer drugs [news]
Nature. 1990 Aug 23;346(6286):685. Unique Identifier : AIDSLINE MED/90356109
Gershon D
Pharmacokinetics of fluconazole in serum and cerebrospinal fluid in a patient with AIDS and cryptococcal meningitis.
Pharmacotherapy. 1990;10(4):305-7. Unique Identifier : AIDSLINE MED/90356467
Chin T; Fong IW; Vandenbroucke A; Department of Pharmacy, St. Michael's Hospital, Toronto, Ontario,; Canada.
The detailed pharmacokinetics of fluconazole in serum and cerebrospinal fluid (CSF) were studied in a patient with acquired immunodeficiency syndrome and cryptococcal meningitis, after an intravenous dose of 400 mg. Fluconazole exhibited a serum elimination half-life of 34.2 hours, distribution volume of 0.56 L/kg, an


Cerebral abnormalities in cocaine abusers: demonstration by SPECT perfusion brain scintigraphy. Work in progress.
Radiology. 1990 Sep;176(3):821-4. Unique Identifier : AIDSLINE MED/90356790
Tumeh SS; Nagel JS; English RJ; Moore M; Holman BL; Department of Radiology, Harvard Medical School, Boston, MA.
Single photon emission computed tomography (SPECT) perfusion brain scans with iodine-123 isopropyl iodoamphetamine (IMP) were obtained in 12 subjects who acknowledged using cocaine on a sporadic to a daily basis. The route of cocaine administration varied from nasal to intravenous. Concurrent abuse of other drugs was


[Buschke-Loewenstein tumor during pregnancy. Apropos of 2 cases]
Rev Fr Gynecol Obstet. 1990 Jun;85(6):375-8. Unique Identifier : AIDSLINE MED/90356960
Picaud A; Faye A; Ogowet-Igumu N; Ozouaki F; Nlome-Nze AR; Departement de Gynecologie-Obstetrique, CHU, Libreville,; Gabon.
The authors report two cases of Buschke-Loewenstein tumors during pregnancy. The considerable development of this giant condyloma requires a caesarean section, to prevent a possible neonatal contamination of the newborn. The course is complicated with recurrences and the treatments are disappointing during the pregnan


[Prevention of HIV infections in prisons]
Soins Psychiatr. 1990 Jun-Jul;(116-117):65-8. Unique Identifier : AIDSLINE MED/90357081
Archer E; Kubiak L; Le Goanvic B; Merlot JM; Moustache B; Veteau P; Vilbois D
HIV and cerebral malaria.
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):201. Unique Identifier : AIDSLINE MED/90357346
Leaver RJ; Haile Z; Watters DA; University Teaching Hospital, Lusaka, Zambia.
AIDS-associated leishmaniasis: an unusual gastro-duodenal presentation.
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):239-40. Unique Identifier : AIDSLINE MED/90357359
Datry A; Similowski T; Jais P; Rosenheim M; Katlama C; Maheu E; Kazaz S; Fassin D; Danis M; Gentilini M; Department of Parasitology, Mycology and Tropical Medicine,; Groupe Hospitalier Pitie-Salpetriere, Paris, France.
Are tuberculosis patients a 'sentinel' population for HIV epidemic in Africa?
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):292. Unique Identifier : AIDSLINE MED/90357374
Hellinger J; Marlink R; Kaptue L; Zekeng L; Essex M; Harvard School of Public Health, Boston, MA 02115.
Is African histoplasmosis an opportunistic fungal infection in AIDS?
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):293. Unique Identifier : AIDSLINE MED/90357375
Carme B; Ngolet A; Ebikili B; Ngaporo AI; Centre Hospitalier et Universitaire de Brazzaville, Congo.
The successful use of marginal cadaveric donor kidneys.
Transplant Proc. 1990 Aug;22(4):1382-3. Unique Identifier : AIDSLINE MED/90357400
Spees EK; Orlowski JP; Temple DM; Colorado Organ Recovery Systems AMI/St. Luke's Medical Center,; University of Colorado Health Sciences Center, Denver 80209.
Medical ignorance, AIDS-Kaposi's sarcoma complex, and the lymphatic system [see comments]
West J Med. 1990 Jul;153(1):17-23. Unique Identifier : AIDSLINE MED/90357828
Witte MH; Witte CL; Way DL; Department of Surgery, University of Arizona College of Medicine,; Tucson 85724.
Ignorance--inevitable but invigorating [editorial; comment]
West J Med. 1990 Jul;153(1):76-7. Unique Identifier : AIDSLINE MED/90357837
Moser RH
A highly aggressive gastric adenocarcinoma associated with human immunodeficiency virus infection [letter]
Am J Gastroenterol. 1990 Sep;85(9):1199-200. Unique Identifier : AIDSLINE MED/90358170
Cappell MS
A peripancreatic abscess containing Aspergillus in a patient with the acquired immune deficiency syndrome [letter]
Am J Gastroenterol. 1990 Sep;85(9):1200. Unique Identifier : AIDSLINE MED/90358171
Bhatt B; Cappell MS
Metastatic liver calcification in adult T-cell leukemia-lymphoma associated with hypercalcemia [letter]
Am J Gastroenterol. 1990 Sep;85(9):1202-3. Unique Identifier : AIDSLINE MED/90358174
Senba M; Kawai K; Chiyoda S; Takahara O
Risk factors and changes in sexual behavior in male homosexuals who seroconverted for human immunodeficiency virus antibodies.
Am J Epidemiol. 1990 Sep;132(3):523-30. Unique Identifier : AIDSLINE MED/90358190
Kuiken CL; van Griensven GJ; de Vroome EM; Coutinho RA; Academic Medical Center, Department of Virology, Amsterdam, The; Netherlands.
In Amsterdam, The Netherlands , a cohort of 982 homosexual and bisexual men has been studied since 1984. Of these, 238 men had antibodies to the human immunodeficiency virus at the onset of the study, and 84 men seroconverted while under study. For each of these seroconversions


AIDS education in the emergency department.
Ann Emerg Med. 1990 Jul;19(7):758-63. Unique Identifier : AIDSLINE MED/90358373
Magid D; Behrman A; Stemhagen A; Jacobson S; Dana Scholars Program, Hospital of the University of; Pennsylvania, Philadelphia 19104.
The prevention of the spread of acquired immunodeficiency syndrome (AIDS) depends on an educated public reducing their risk of infection. To test the hypothesis that effective community AIDS education can be based in an emergency department, we designed and evaluated two educational interventions in a high-volume urba


Emergency medicine education and the HIV epidemic [editorial]
Ann Emerg Med. 1990 Jul;19(7):830-1. Unique Identifier : AIDSLINE MED/90358389
Binder LS
Dodging droplet nuclei. Reducing the probability of nosocomial tuberculosis transmission in the AIDS era [editorial]
Am Rev Respir Dis. 1990 Sep;142(3):501-3. Unique Identifier : AIDSLINE MED/90358435
Nardell EA
Cytotoxic events taking place in the lung of patients with HIV-1 infection. Evidence of an intrinsic defect of the major histocompatibility complex-unrestricted killing partially restored by the incubation with rIL-2.
Am Rev Respir Dis. 1990 Sep;142(3):516-22. Unique Identifier : AIDSLINE MED/90358439
Agostini C; Zambello R; Trentin L; Feruglio C; Masciarelli M; Siviero F; Poletti V; Spiga L; Gritti F; Semenzato G; Department of Clinical Medicine, Padua University School of; Medicine, Italy.
To characterize the cytotoxic events taking place in the lung of patients with HIV-1 infection, we studied the cells recovered from the bronchoalveolar lavage (BAL) of nine patients with AIDS, seven patients with AIDS-related complex, and two patients with lymphadenopathy. Phenotypic analysis was coupled to a series o


Diagnostic significance of increased bronchoalveolar lavage fluid eosinophils.
Am Rev Respir Dis. 1990 Sep;142(3):642-7. Unique Identifier : AIDSLINE MED/90358460
Allen JN; Davis WB; Pacht ER; Department of Internal Medicine, Ohio State University Hospitals,; Columbus.
We determined the incidence of increased bronchoalveolar lavage (BAL) fluid eosinophil percentages in 1,059 consecutive patients undergoing bronchoscopy with BAL over a 33-month period. Forty-eight (48) patients were found to have 5% or more BAL eosinophils. The most common causes for increased BAL eosinophils were in


[The influence of macrophages on the leukemogenic activity of Rauscher murine leukemia virus]
Arch Geschwulstforsch. 1990;60(4):279-82. Unique Identifier : AIDSLINE MED/90358651
Sydow G; Sydow H; Zentralinstitut fur Krebsforschung, Akademie der Wissenschaften; der DDR, Robert-Rossle-Institut, Berlin-Buch.
A single application of trypan blue 3 to 24 hours before or simultaneous with inoculation of the Rauscher leukemia virus (RLV) resulted in enhancement of leukemogenesis with an especially high viremia. Repeated administration of trypan blue after RLV infection resulted in reduced spleen weight. Viremia, however, was a


Strategy for AIDS [editorial]
Aust N Z J Surg. 1990 Aug;60(8):563-4. Unique Identifier : AIDSLINE MED/90358713
Dudley HA
Strategy for AIDS.
Aust N Z J Surg. 1990 Aug;60(8):567-9. Unique Identifier : AIDSLINE MED/90358715
Royle JP; Syme RR
Mycoplasma can enhance HIV replication in vitro: a possible cofactor responsible for the progression of AIDS.
Biochem Biophys Res Commun. 1990 Aug 16;170(3):1365-70. Unique Identifier : AIDSLINE MED/90358844
Chowdhury IH; Munakata T; Koyanagi Y; Kobayashi S; Arai S; Yamamoto N; Department of Virology and Parasitology, Yamaguchi University; School of Medicine, Japan.
Mycoplasma membrane protein (MMP) augmented HIV production from MOLT-4 cells chronically infected by HIV. A nearly 3-fold increase of HIV p24 antigen was detected in MMP-treated culture as compared to control culture at 100 micrograms/ml. MMP also augmented HIV production in different T cells chronically infected by H


Comment on the article by Espinoza et al [letter; comment]
Arthritis Rheum. 1990 Aug;33(8):1295-6. Unique Identifier : AIDSLINE MED/90358921
Hess EV; Solinger AM
Expression and characterization of human CD4:immunoglobulin fusion proteins.
DNA Cell Biol. 1990 Jun;9(5):347-53. Unique Identifier : AIDSLINE MED/90321469
Zettlmeissl G; Gregersen JP; Duport JM; Mehdi S; Reiner G; Seed B; Research Laboratories of Behringwerke AG, Marburg, West Germany.
Different chimeric antibody-like molecules consisting of the four human CD4 extracellular domains (amino acids 1-369) fused to different parts of human IgG1 and IgM heavy-chain constant regions have been created and expressed in mammalian cells. For both IgG1 and IgM fusion proteins, the best expression in COS cells w


Bibliography of the current world literature.
AIDS. 1990 May;4(5):A27-30. Unique Identifier : AIDSLINE MED/90321482
Non-organic psychiatric and psychosocial syndromes associated with HIV-1 infection and disease.
AIDS. 1990 May;4(5):381-8. Unique Identifier : AIDSLINE MED/90321483
Miller D; Riccio M; Social and Behavioural Research Unit, Global Programme on AIDS,; World Health Organization, Geneva, Switzerland.
Parameters involved in the cell fusion induced by HIV.
AIDS. 1990 May;4(5):409-15. Unique Identifier : AIDSLINE MED/90321487
Tang SB; Levy JA; Cancer Research Institute, University of California, School of; Medicine, San Francisco 94143.
Studies evaluating cell fusion by HIV indicate that optimal conditions for measuring this biological process involve the use of appropriate numbers of cells, the expression of HIV gp120 in infected cells, the presence of the CD4 protein on the surface of uninfected cells, and sugar moieties. Cellular metabolism and nu


Detection of salivary immunoglobulin A antibodies to HIV-1 in infants and children.
AIDS. 1990 May;4(5):417-20. Unique Identifier : AIDSLINE MED/90321488
Archibald DW; Johnson JP; Nair P; Alger LS; Hebert CA; Davis E; Hines SE; Department of Oral Pathology, University of Maryland, Baltimore; 21201.
Secretory immunoglobulin A (slgA) antibodies of non-maternal origin are present in newborns and slgA to HIV-1 antigens has been detected in infected adults. In this study we investigated the presence of HIV-1-specific IgA in saliva from 41 children (aged 1 day-46 months) born to women at risk for HIV-1 infection. Sali


Temporary increase in serum beta 2-microglobulin during treatment with interferon-alpha for AIDS-associated Kaposi's sarcoma.
AIDS. 1990 May;4(5):459-62. Unique Identifier : AIDSLINE MED/90321495
de Wit R; Bakker PJ; Reiss P; Hoek FJ; Lange JM; Goudsmit J; Veenhof KH; Department of Medicine, Academic Medical Center, Amsterdam, The; Netherlands.
Beta 2-microglobulin (beta 2-M) levels were determined in the serum of 24 patients treated with high-dose human recombinant interferon-alpha (IFN alpha) for AIDS-associated Kaposi s sarcoma. There was a significant increase in serum beta 2-M levels, irrespective of the response to treatment. However, the increase of s


Empyema of the gallbladder in a patient with AIDS-related complex.
Clin Imaging. 1990 May;14(2):157-8. Unique Identifier : AIDSLINE MED/90322246
Yao L; Scialdone C; Department of Radiology, Albany Medical Center Hospital, New York; 12208.
A case of staphylococcus aureus empyema of the gallbladder in a patient with AIDS-related complex is presented. The case is remarkable for the indolence of the clinical presentation and the magnitude of gallbladder dilatation noted at computed tomographic (CT) examination. Empyema of the gallbladder may constitute an


Beneficial effects of the thymic hormone preparation thymostimulin in patients with defects in cell-mediated immunity and chronic purulent rhinosinusitis. A double-blind cross-over trial on improvements in monocyte polarization and clinical effects.
Clin Exp Immunol. 1990 Jun;80(3):304-13. Unique Identifier : AIDSLINE MED/90322720
Tas M; Leezenberg JA; Drexhage HA; Laboratory for Clinical Immunology, Free University Hospital,; Amsterdam, The Netherlands.
Twenty patients with chronic purulent rhinosinusitis were treated with TP-1 (Serono; 1 mg/kg body weight), in a double-blind cross-over trial. TP-1 was administered by daily i.m. injections for the first 14 days followed by two injections/week for 6 further weeks. The patients were immunologically special in that they


[Perioperative blood coagulation therapy and diagnosis]
Infusionstherapie. 1990 Apr;17 Suppl 2:9-19. Unique Identifier : AIDSLINE MED/90323934
Kretschmer V; Abt. fur Transfusionsmedizin und Gerinnungsstorung, Klinikum; der Philipps-Universitat Marburg.
The risks and adverse reactions of fresh frozen plasma (FFP) and coagulation components have changed considerably in the last few years because of the spread of HIV on the one hand, and the advances in preparation and sterilisation of the coagulation components on the other hand. Therefore, the indication for FFP and


Comparative evaluation of an immunofluorescent antibody test, enzyme immunoassay and western blot for the detection of HIV-1 antibody.
Intervirology. 1990;31(2-4):122-8. Unique Identifier : AIDSLINE MED/90324048
Iltis JP; Patel NM; Lee SR; Barmat SL; Wallen WC; Wampole Laboratories and Carter-Wallace Diagnostics, Cranbury,; N.J. 08512.
Screening blood and blood products for human immunodeficiency virus type 1 (HIV-1) antibody is predominantly performed by enzyme immunoassay (EIA), and results must be confirmed by the more immunospecific Western blot (WB) assay. This study evaluated an HIV immunofluorescent antibody (IFA) test relative to WB assay fo


Multicenter HIV and hepatitis B seroprevalence study.
J Emerg Med. 1990 May-Jun;8(3):243-51. Unique Identifier : AIDSLINE MED/90324530
Jui J; Modesitt S; Fleming D; Stevens P; Wayson B; Hulman S; Schriver JA; Division of Emergency Medicine, Oregon Health Sciences; University, Portland 97201-3098.
Prior single institutional investigations have found unrecognized HIV seroprevalence in emergency department (ED) patients to range from 0.38% to 4%. A prospective, anonymous study of HIV and hepatitis B (HB) seroprevalence was performed on excess serum of all ED patients over two 48-hour periods in May and August, 19


Human T-cell lymphotropic virus-type I.
Infect Control Hosp Epidemiol. 1990 Jun;11(6):314-8. Unique Identifier : AIDSLINE MED/90324560
Larkin J; Sinnott JT 4th; Weiss J; Holt DA; Department of Internal Medicine, University of South Florida,; College of Medicine, Tampa.
HTLV-I is a retrovirus now identified as the etiologic agent of two diverse disease processes: ATLL, an aggressive T-cell malignancy; and TSP/HAM, a chronic progressive myelopathy. Transmission can occur horizontally through blood transfusions, IV drug abuse and sexual intercourse. Vertical transmission may also occur


Novel fatty acyl substrates for myristoyl-CoA:protein N-myristoyl-transferase.
J Lipid Res. 1990 Jun;31(6):1121-9. Unique Identifier : AIDSLINE MED/90324805
Heuckeroth RO; Jackson-Machelski E; Adams SP; Kishore NS; Huhn M; Katoh A; Lu T; Gokel GW; Gordon JI; Department of Biochemistry and Molecular Biophysics, Washington; University School of Medicine, St. Louis, MO 63110.
Myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyzes the covalent attachment of myristic acid to the NH2-terminal Gly residues of a number of viral and cellular proteins. The remarkable specificity of this enzyme for myristoyl CoA observed in vivo appears to arise in large part from a cooperativity between NMT


Amphotericin B in urological practice.
J Urol. 1990 Aug;144(2 Pt 1):215-23. Unique Identifier : AIDSLINE MED/90325315
Wise GJ; Urology Division, Maimonides Medical Center, Brooklyn, New York.
Scientifically astute activists seek common ground with clinicians on testing new AIDS drugs [news]
JAMA. 1990 Aug 8;264(6):666, 669-70, 673. Unique Identifier : AIDSLINE MED/90325444
Cotton P
From the Food and Drug Administration.
JAMA. 1990 Aug 8;264(6):677. Unique Identifier : AIDSLINE MED/90325445
Nightingale SL; Office of Health Affairs, FDA, Rockville, MD 20857.
[Malaria tropica in HIV infection]
Klin Wochenschr. 1990 May 17;68(10):533-6. Unique Identifier : AIDSLINE MED/90325657
Weinke T; Scherer W; Pohle HD; Universitatsklinikum Rudolf Virchow, Freie Universitat Berlin,; II. Medizinische Klinik, Berlin.
This is a case report of a 24 year-old woman who is HIV-infected since three years (stage III B, CDC). She developed malaria tropica during her touristic stay in the Cameroons, Africa. No clinical complications were detectable even though she had a high parasitemia of 18% blood cells infected with Plasmodium falciparu


HIV screening: nosocomial epidemiologic risks and decision analysis.
Law Med Health Care. 1990 Spring-Summer;18(1-2):33-40. Unique Identifier : AIDSLINE MED/90325800
Pauker SG
Histoplasma capsulatum infections of the central nervous system. A clinical review.
Medicine (Baltimore). 1990 Jul;69(4):244-60. Unique Identifier : AIDSLINE MED/90325995
Wheat LJ; Batteiger BE; Sathapatayavongs B; Indiana University School of Medicine, Indianapolis.
Central nervous system manifestations occur in 10 to 20% of patients with disseminated histoplasmosis. Additionally, histoplasmosis may be the cause of cases of chronic meningitis in patients with no other evidence for dissemination. Histoplasmosis may also cause cerebral or spinal cord mass lesions resembling neoplas


[Lung deposition of 300 and 600 mg pentamidine, inhaled with 3 different inhalers]
Med Klin. 1990 Apr;85 Suppl 2:251-4. Unique Identifier : AIDSLINE MED/90326034
Matthys H; Herceg R; Abteilung Pneumologie, Medizinische Universitatsklinik Freiburg.
Intracorporal, especially pulmonary, and extracorporal deposition of pentamidine was studied following inhalation of 300 or 600 mg in 6 ml Aqua dest. each dose in six patients with one previous episode of pneumocystis carinii pneumonia. Three different nebulizers--two mechanical nebulizers (Respirgard II and Pari-IS-2


[Unwanted drug side effects with pentamidine inhalation]
Med Klin. 1990 Apr;85 Suppl 2:255-7. Unique Identifier : AIDSLINE MED/90326035
L'age M; Arasteh K; II. Innere Abteilung des Auguste-Viktoria-Krankenhauses,; Berlin-Schoneberg.
The incidence of systemic side effects under aerosolized pentamidine treatment or prophylaxis for pneumocystis carinii pneumonia is low when compared to intravenous application. Erythema, hypotension, hypoglycemia, renal failure are infrequently seen. Local side effects--cough, bronchial spasm, metallic taste--are fre


[Therapy of HIV associated mild and moderately severe Pneumocystis carinii pneumonia with 600 mg/die pentamidine aerosol. Results of a multicenter study]
Med Klin. 1990 Apr;85 Suppl 2:258-9. Unique Identifier : AIDSLINE MED/90326036
Meyer A; Dorlemann A; Dietrich M; Bernhard-Nocht-Institut fur Tropenmedizin, Hamburg.
In 22 HIV positive patients a mild to moderate pneumocystis carinii pneumonia was treated by daily inhalation for 21 days of 600 mg pentamidine, divided into two inhalation phases with the inhalation of 300 mg pentamidin each. In 13 patients (59%) treatment was successful. In five cases, therapy was stopped in the fir


[Treatment of mild to moderately severe Pneumocystis carinii pneumonia with cotrimoxazole versus pentamidine aerosol. Preliminary results of a prospective randomized therapy study]
Med Klin. 1990 Apr;85 Suppl 2:260-3. Unique Identifier : AIDSLINE MED/90326037
Arasteh K; Heise W; L'age M; Auguste-Viktoria-Krankenhaus, Berlin-Schoneberg.
In an open, prospective, randomized study we compared efficacy and side effects of 8 g/d cotrimoxazole (TMP/SMX) i.v. vs. 600 mg aerosolized pentamidine. 29 of 60 planned case record forms are now evaluated. Efficacy in both groups was comparable, but side effects in the pentamidine arm were very rare (7.2% vs. 40% in


Primary prevention of Pneumocystis carinii pneumonia by inhalation of pentamidine. Preliminary results from a placebo-controlled randomized trial. Swiss Group for Clinical Studies on AIDS.
Med Klin. 1990 Apr;85 Suppl 2:268-70. Unique Identifier : AIDSLINE MED/90326039
Hirschel B; Chopard P; Chave JP; Furrer HJ; Opravil M; Hilti P; Vernazza P; Lazzarin A; Division of Infectious Diseases, Hopital Cantonal Universitaire,; Geneva, Switzerland.
Patients with AIDS but without pneumocystis carinii pneumonia, patients with advanced AIDS-related complex (ARC), and asymptomatic patients with less than 200 CD4-positive lymphocytes/mm3 were randomized to one of two groups: group I: Inhalation of 300 mg of pentamidine every 28 days; group II: Inhalation of placebo (


[Preventive pentamidine inhalation of Pneumocystis carinii pneumonia in patients with immune deficiency. Preliminary evaluation of a multicenter study]
Med Klin. 1990 Apr;85 Suppl 2:276-80. Unique Identifier : AIDSLINE MED/90326041
Schrappe-Bacher M; Fatkenheuer G; Salzberger B; Zehrer I; Bendick C; Rasokat H; Medizinische Klinik II und Poliklinik, Universitat zu Koln.
In the first evaluation of an uncontrolled multicenter study on inhalative pentamidine prophylaxis (300 mg pentamidine-isethionate monthly) of pneumocystis carinii pneumonia in immunocompromised patients, 48 patients (all 48 patients HIV1-infected, 36 without preceding pneumocystis carinii pneumonia (primary prophylax


[Randomized comparative study of secondary prevention of Pneumocystis carinii pneumonia in patients with acquired immunologic deficiency syndrome]
Med Klin. 1990 Apr;85 Suppl 2:281-5. Unique Identifier : AIDSLINE MED/90326042
Hoffken G; Elsing C; Ruhnke M; Franke M; Schrappe-Bacher M; Stellbrink HJ; Weiss R; Noack H; Petri M; Lode H; et al; Prophylaxe-Studiengruppe Pneumocystis-carinii-Pneumonie,; Paul-Ehrlich-Gesellschaft fur Chemotherapie, e.V.
Pneumocystis carinii pneumonia is one of the most frequent infectious complications in patients with the acquired immunodeficiency syndrome (AIDS). A prospective trial was initiated to compare azidothymidine alone with azidothymidine plus aerosolized pentamidine as a secondary prophylaxis for pneumocystis carinii pneu


Fungal infections in patients infected with HIV.
Mo Med. 1990 Jun;87(6):348-50. Unique Identifier : AIDSLINE MED/90326063
Powderly WG; Department of Medicine, Washington University School of Medicine.
HIV-positive patients are at risk for a number of serious fungal infections. The author reviews the common fungal infections and stresses the importance of early detection and appropriate treatment.


First UK trial of AIDS vaccine approved [news]
Nature. 1990 Jul 26;346(6282):303. Unique Identifier : AIDSLINE MED/90326168
Concar D
[Splenectomy in diseases of the blood system]
Sov Med. 1990;(4):31-6. Unique Identifier : AIDSLINE MED/90327177
Epifanov NS
Zidovudine update: 1990.
DICP. 1990 Jul-Aug;24(7-8):754-60. Unique Identifier : AIDSLINE MED/90327811
Morse GD; Lechner JL; Santora JA; Rozek SL; State University of New York, Buffalo.
Zidovudine (ZDV) is the only approved antiviral for the treatment of human immunodeficiency virus infection (HIV) in the U.S. Although newer antivirals have reached Phase II testing, ZDV is now the accepted therapy against which all other agents will be compared. Zidovudine 1500 mg/d was previously prescribed only to


Fluconazole, a new antifungal agent.
Ann Intern Med. 1990 Aug 1;113(3):177-9. Unique Identifier : AIDSLINE MED/90328536
Galgiani JN; Veterans Affairs Medical Center, Tucson, AZ.
Fluconazole compared with amphotericin B plus flucytosine for cryptococcal meningitis in AIDS. A randomized trial [see comments]
Ann Intern Med. 1990 Aug 1;113(3):183-7. Unique Identifier : AIDSLINE MED/90328538
Larsen RA; Leal MA; Chan LS; Los Angeles County Hospital, California.
OBJECTIVE: To compare the efficacy of fluconazole with amphotericin B plus flucytosine in the treatment of cryptococcal meningitis. DESIGN: Patients were randomly assigned to oral fluconazole, 400 mg/d, for 10 weeks or to amphotericin B, 0.7 mg/kg body weight daily for 1 week, then three times weekly for 9 weeks combi


Inhaled or intravenous pentamidine therapy for Pneumocystis carinii pneumonia in AIDS. A randomized trial [published erratum appears in Ann Intern Med 1990 Oct 1;113(7):561] [see comments]
Ann Intern Med. 1990 Aug 1;113(3):195-202. Unique Identifier : AIDSLINE MED/90328540
Soo Hoo GW; Mohsenifar Z; Meyer RD; Cedars-Sinai Medical Center, Los Angeles, California.
OBJECTIVE: To compare inhaled pentamidine with intravenous pentamidine for the treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome (AIDS). DESIGN: A randomized trial. SETTING: Community teaching hospital and hospital-based outpatient treatment center. PATIENTS: Twenty-one homosexual m


Intravenous or inhaled pentamidine for treating Pneumocystis carinii pneumonia in AIDS. A randomized trial [see comments]
Ann Intern Med. 1990 Aug 1;113(3):203-9. Unique Identifier : AIDSLINE MED/90328541
Conte JE Jr; Chernoff D; Feigal DW Jr; Joseph P; McDonald C; Golden JA; School of Medicine, University of California, San Francisco.
OBJECTIVE: To evaluate the efficacy and toxicity of aerosolized pentamidine and of reduced-dose intravenous pentamidine for the treatment of mild to moderate Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS). DESIGN: Randomized open study with serial pulmonary function testi


Alcohol, sex and AIDS [see comments]
Alcohol Alcohol. 1990;25(2-3):293-301. Unique Identifier : AIDSLINE MED/90329075
Plant MA; Department of Psychiatry, University of Edinburgh, Scotland, U.K.
The association between alcohol consumption and AIDS risks is examined. It is concluded that chronic heavy drinking or alcohol consumption levels consistent with alcohol dependence or alcohol-related liver disease does damage the immune system. In addition alcohol consumption influences sexual behaviour for a variety


Oral manifestations of HIV infection, Part I.
Compendium. 1990 Mar;11(3):150-4, 156. Unique Identifier : AIDSLINE MED/90329660
Haring JI
Several signs of human immunodeficiency virus (HIV) infection, such as candidiasis, hairy leukoplakia, and Kaposi s sarcoma, may first appear in the mouth. The dentist is in a unique position to detect the oral manifestations of HIV infection. The purpose of this review article is to provide the dentist with baseline


Consensus conference evaluates key issues concerning use of intravenous immune globulin [news]
Clin Pharm. 1990 Jul;9(7):489, 492-3. Unique Identifier : AIDSLINE MED/90329738
Clinical uses of intravenous immune globulin [see comments]
Clin Pharm. 1990 Jul;9(7):509-29. Unique Identifier : AIDSLINE MED/90329743
Knapp MJ; Colburn PA; University of Michigan Medical Center, Ann Arbor.
The preparation, pharmacokinetics, clinical uses, dosage and administration, and adverse effects of intravenous immune globulin (IVIG) are reviewed. IVIG, which consists primarily of immunoglobulin G (IgG), is initially prepared from pooled human plasma by using the Cohn-Oncley fractionation procedure. Secondary treat


Recurrent pneumothorax in AIDS patients with Pneumocystis pneumonia. A clinicopathologic report of three cases and review of the literature.
Chest. 1990 Aug;98(2):266-70. Unique Identifier : AIDSLINE MED/90329815
Beers MF; Sohn M; Swartz M; Cardiovascular Pulmonary Division, Hospital, University of; Pennsylvania, Philadelphia 19104.
Spontaneous pneumothorax associated with Pneumocystis carinii pneumonia (PCP) in AIDS patients has been reported with increasing frequency; however, little is known about the causative histopathology. In the past year, we treated three patients with documented PCP subsequently complicated by multiple spontaneous pneum


The radiographic appearance of pulmonary nocardiosis associated with AIDS [see comments]
Chest. 1990 Aug;98(2):382-5. Unique Identifier : AIDSLINE MED/90329836
Kramer MR; Uttamchandani RB; Department of Medicine, University of Miami School of Medicine.
Pulmonary nocardiosis is a well-described infection in immunocompromised patients; however, it is less well documented in patients with AIDS. The pulmonary manifestation in 21 HIV-positive patients who developed pulmonary infection with Nocardia asteroides is described. The radiographic picture included lobar or multi


Virology of the human immunodeficiency virus type 1.
Ear Nose Throat J. 1990 Jun;69(6):376, 379-84. Unique Identifier : AIDSLINE MED/90330004
Buchbinder A; Veterans Affairs Medical Center, Manhattan, NY.
Understanding the mode of replication of the human immunodeficiency virus (HIV) is necessary for explaining the natural history of HIV infection and for the development of therapeutic and prophylactic agents. The life cycle of HIV involves infective particles, the attachment of the virus to specific cell receptors, re


Occupational transmission of human immunodeficiency virus.
Ear Nose Throat J. 1990 Jun;69(6):401-5. Unique Identifier : AIDSLINE MED/90330006
Polis MA; Critical Care Medicine Department, Warren Grant Magnuson Clinical; Center, National Institutes of Health, Bethesda, MD.
As the number of patients requiring treatment for HIV-1 infection has increased, there has been increasing concern among health-care providers regarding the risks of occupational infection. Fortunately, this risk is low and may be made lower by adherence to infection-control guidelines. The incidence of occupational i


Pathologic manifestations of acquired immunodeficiency syndrome in the head and neck.
Ear Nose Throat J. 1990 Jun;69(6):406-15. Unique Identifier : AIDSLINE MED/90330007
Wenig BM; Kuruvilla A; Goldrich MS; Heffner DK; Tuur S; Department of Otolaryngic Pathology, Armed Forces Institute of; Pathology, Washington, DC.
Various diseases of the head and neck that appear in association with AIDS have been delineated. These diseases may be the initial manifestations of AIDS or may be part of systemic involvement following HIV infection. Both clinicians and pathologists must be aware of the protean manifestations of AIDS in order to esta


Head and neck manifestations of the acquired immunodeficiency syndrome in children.
Ear Nose Throat J. 1990 Jun;69(6):416-9, 422-3. Unique Identifier : AIDSLINE MED/90330008
Chow JH; Stern JC; Kaul A; Pincus RL; Gromisch DS; Department of Pediatric Infectious Diseases, New York Medical; College (Lincoln Hospital), NY.
The head-and-neck manifestations of HIV infection in children are very different from those in the adult population. Recurrent bacterial and viral infections are common manifestations, and persistent sinusitis or otitis media should make the otolaryngologist suspicious of HIV infection if the child has been exposed to


Upper and lower airway manifestations of human immunodeficiency virus infection.
Ear Nose Throat J. 1990 Jun;69(6):424-31. Unique Identifier : AIDSLINE MED/90330009
Ognibene FP; Critical Care Medicine Department, Warren G, Magnuson Clinical; Center, National Institutes of Health, Bethesda, MD.
Patients with HIV infection can have a variety of infectious, neoplastic, and noninfectious but inflammatory processes that involve their upper or lower airways. Knowledge of these pathologic processes as well as a suitable diagnostic approach are essential to care effectively for these patients.


Oral candidosis: an old disease in new guises.
Dent Update. 1990 Jan-Feb;17(1):36-8. Unique Identifier : AIDSLINE MED/90330065
Samaranayake LP
[Intestinal protozoa--new aspects]
Internist (Berl). 1990 Jun;31(6):386-98. Unique Identifier : AIDSLINE MED/90330421
Eckert J; Jacquier P; Weber R; Institut fur Parasitologie, Universitat Zurich.
[Symptomatic HIV infection. Approaches to rational therapy]
Monatsschr Kinderheilkd. 1990 May;138(5):249-53. Unique Identifier : AIDSLINE MED/90331941
Debatin KM; Sektion Onkologie/Immunologie, Universitats-Kinderklinik; Heidelberg.
The symptomatic HIV-infection is characterized by the involvement of multiple organs with a predominance of infectious complications. Treatment of these complications usually follows established therapeutic regimens for the resulting diseases of affected organs. Successful reconstitution of the immunodeficiency result


[Neurologic problems in HIV infection. A current overview]
Nervenarzt. 1990 Jun;61(6):340-50. Unique Identifier : AIDSLINE MED/90332087
Enzensberger W; Fischer PA; Abteilung fur Neurologie, Klinikum der J.W. Goethe-Universitat,; Frankfurt/Main.
[Therapeutic aspects of salmonellosis in AIDS]
Pathol Biol (Paris). 1990 Apr;38(4):298-301. Unique Identifier : AIDSLINE MED/90332312
Dellamonica P; Mondain V; Bernard E; Service des Maladies Infectieuses et Tropicales, Hopital de; l'Archet, Nice, France.
For the HIV positive patient, salmonella raises numerous epidemiological and therapeutic problems. This microorganism, quite common before zidovudine therapy, seems to have diminished since this antiviral also has an antibiotic activity against salmonella. When bacterial contamination occurs, the decreased immunitary


Treatment of Pneumocystis carinii pneumonia with 1,3-beta-glucan synthesis inhibitors.
Proc Natl Acad Sci U S A. 1990 Aug;87(15):5950-4. Unique Identifier : AIDSLINE MED/90332699
Schmatz DM; Romancheck MA; Pittarelli LA; Schwartz RE; Fromtling RA; Nollstadt KH; Vanmiddlesworth FL; Wilson KE; Turner MJ; Department of Biochemical Parasitology, Merck Sharp & Dohme; Research Laboratories, Rahway, NJ 07065.
Pneumocystis carinii pneumonia is a major cause of death in AIDS patients in the United States . The presently available treatments have limited use due to a high incidence of adverse reactions. Therefore, there is an urgent need for a safer method for treatment and prevention of this d


CD4 inserted in red blood cell membranes or reconstituted in liposome bilayers as a potential therapeutic agent against AIDS.
Prog Clin Biol Res. 1990;343:147-77. Unique Identifier : AIDSLINE MED/90332729
Nicolau C; Tosi PF; Arvinte T; Mouneimne Y; Cudd A; Sneed L; Madoulet C; Schulz B; Barhoumi R; Section of Cell Biology, Texas A&M University, College Station; 77843-2401.
Fusion of human immunodeficiency virus type 1 (HIV-1) with human cells as measured by membrane fluorescence dequenching (DQ) method; roles of HIV-1-cell fusion in AIDS pathogenesis.
Prog Clin Biol Res. 1990;343:179-98. Unique Identifier : AIDSLINE MED/90332731
Volsky DJ; Molecular Virology Laboratory, St. Luke's/Roosevelt Hospital; Center, New York, N.Y.
HIV-1, the primary etiologic agent of AIDS, is a non-transforming human retrovirus which shares many physical and functional characteristics with viruses from the lentivirus family. One of these characteristics is that HIV-1 infection has profound cytopathic effects on host cells. Studies by the membrane fluorescence


Acute abdomen in AIDS: CT diagnosis and triage.
Radiographics. 1990 Jul;10(4):621-34. Unique Identifier : AIDSLINE MED/90332987
Kuhlman JE; Fishman EK; Russell P. Morgan Department of Radiology and Radiological; Sciences, Johns Hopkins Medical Institutions, Baltimore, MD; 21205.
Computed tomographic (CT) scans of 80 patients with acquired immunodeficiency syndrome (AIDS) and acute abdominal pain were reviewed for the purpose of highlighting the use of CT in diagnosis and triage. Common and uncommon causes of acute abdominal pain in patients with AIDS are discussed and their CT findings illust


[Clinical studies of interleukin-2]
Revmatologiia (Mosk). 1990 Jan-Mar;(1):50-5. Unique Identifier : AIDSLINE MED/90333180
Mordvinov AV; Purin' VI; Simakhodskii AS
Granulocyte-macrophage colony-stimulating factor in human immunodeficiency virus disease.
Semin Hematol. 1990 Jul;27(3 Suppl 3):8-14. Unique Identifier : AIDSLINE MED/90333269
Groopman JE; Division of Hematology/Oncology, New England Deaconess Hospital,; Harvard Medical School, Boston, MA 02150.
Factors contributing to the development of cytopenias in patients with advanced human immunodeficiency virus (HIV) disease include primary HIV-related suppression of blood cell production, opportunistic infections and neoplasms that directly involve the marrow cavity, and the toxicity of antiviral, antiinfective, and


[The prevention of the transmission of the human immunodeficiency virus in ophthalmological practice]
Vestn Oftalmol. 1990 Jan-Feb;106(1):67-9. Unique Identifier : AIDSLINE MED/90333513
Indeikin EN
[The oncological aspects of infection caused by the human immunodeficiency virus]
Vopr Onkol. 1990;36(5):515-22. Unique Identifier : AIDSLINE MED/90333612
Aliev DA; Mamedov MK
[Preventive vaccinations in HIV infected patients]
Z Arztl Fortbild (Jena). 1990;84(8):385-6. Unique Identifier : AIDSLINE MED/90333697
Dittmann S; Zentralinstitut fur Hygiene, Mikrobiologie und Epidemiologie der; DDR.
[Current developments in dermatologic virology]
Z Hautkr. 1990 May;65(5):460, 463-6, 469-70. Unique Identifier : AIDSLINE MED/90333755
Nasemann T
We give a survey of the latest developments in dermatovirology. The actual epidemiologic situation is described with special reference to the increasing incidences of AIDS, condylomata acuminata, mollusca contagiosa, and herpes simplex type 2. The dermatovirological progress achieved during the last few years is mostl


Human immunodeficiency virus and the fetus.
J Am Board Fam Pract. 1990 Jul-Sep;3(3):181-93. Unique Identifier : AIDSLINE MED/90333959
Fletcher JL Jr; Department of Family Medicine, Medical College of Georgia 30912.
About 2 percent of current cases of acquired immunodeficiency syndrome are among patients less than 13 years of age. When a woman infected by the human immunodeficiency virus (HIV) becomes pregnant, her neonate has approximately a 40 percent chance of becoming infected vertically in the perinatal period. Experience in


Host factors in the severity of Q fever.
Ann N Y Acad Sci. 1990;590:33-8. Unique Identifier : AIDSLINE MED/90334341
Raoult D; Centre National de Reference des Rickettsies, Chu La Timone,; Marseille, France.
The author has reviewed different aspects of the role of immunocompetence in the development of Q fever. Coxiella burnetii lives within the phagolysosomes of infected cells. In animals, the immunosuppression caused by either cortisone or X-irradiation reactivates Q fever. In humans, cases of Q fever are reported in im


Interactions of HIV gp120 with the CD4 molecule on lymphocytes and in the nervous system.
Ann N Y Acad Sci. 1990;594:355-61. Unique Identifier : AIDSLINE MED/90334403
Sattentau QJ; Howard Hughes Medical Institute, College of Physicians and; Surgeons, Columbia University, New York, New York 10032.
[Are cialit-preserved ossicles as middle ear implants still bacteriologically defensible? Their replacement by pre-formed implants fashioned from teeth]
Laryngorhinootologie. 1990 Jun;69(6):327-32. Unique Identifier : AIDSLINE MED/90334656
Huttenbrink KB; Weidenfeller P; HNO-Universitatsklinik Munster.
Recent studies have demonstrated a limited bactericidal activity of Cialit in the preservation of otologic transplants. The authors therefore performed several tests following routine treatment of the grafts. First, the contamination of allogenic ossicles was studied; afterwards, the bactericidal activity of Cialit wa


[Immune thrombocytopenia and HIV-1 infection. Response to splenectomy]
Rev Esp Enferm Dig. 1990 Mar;77(3):225-6. Unique Identifier : AIDSLINE MED/90334915
Planells Roig MV; Pallas Regueria JA; Carbonell Tatay F; Sancho Fornos S; Servicio de Cirugia General y Aparato Digestivo, Hospital La Fe,; Valencia.
We present a case of thrombocytopenic purpura associated to acquired immunodeficiency; this disease is very infrequently associated to AIDS; the clinical characteristics are similar to the classical Idiopathic Thrombocytopenic Purpura, including the response to splenectomy. We discuss the therapeutic approach of this


Subcutaneous recombinant granulocyte-macrophage colony-stimulating factor used as a single agent and in an alternating regimen with azidothymidine in leukopenic patients with severe human immunodeficiency virus infection [see comments]
Blood. 1990 Aug 1;76(3):463-72. Unique Identifier : AIDSLINE MED/90335430
Pluda JM; Yarchoan R; Smith PD; McAtee N; Shay LE; Oette D; Maha M; Wahl SM; Myers CE; Broder S; Clinical Oncology Program, National Cancer Institute, Bethesda,; MD 20892.
We investigated the effects of recombinant human granulocyte-macrophage colony-stimulating factor (rGM-CSF) administered by the subcutaneous route, first alone and then alternating with azidothymidine ( AZT ), in leukopenic patients with severe human im


Human immunodeficiency virus DNA amplification and serology in blood donors.
Blood. 1990 Aug 1;76(3):641-5. Unique Identifier : AIDSLINE MED/90335456
Perrin LH; Yerly S; Adami N; Bachmann P; Butler-Brunner E; Burckhardt J; Kawashima E; Department of Medicine, Cantonal University Hospital, Geneva,; Switzerland.
The significance of indeterminate screening antibody test for human immunodeficiency virus (HIV) serology is still difficult to evaluate, especially in low-risk populations. One hundred twenty-seven blood donors with an initially reactive screening test for HIV antibodies were enrolled in this study. The sera of 95 of


Clinical trials for patients with AIDS or HIV infection [letter]
Can Med Assoc J. 1990 Aug 1;143(3):173-4. Unique Identifier : AIDSLINE MED/90335722
Mackie ID
Population pharmacokinetics of zidovudine. The Veterans Administration Cooperative Studies Group.
Clin Pharmacol Ther. 1990 Aug;48(2):161-7. Unique Identifier : AIDSLINE MED/90336267
Gitterman SR; Drusano GL; Egorin MJ; Standiford HC; Department of Medicine, University of Maryland Cancer Center,; Baltimore.
The epidemic of human immunodeficiency virus infection has forced an unprecedented acceleration of drug development. The lack of effective therapy at present against many of the infectious complications of acquired immunodeficiency syndrome (AIDS) has forced the rapid clinical introduction of new agents. Population ph


Biologic skin substitutes.
Clin Plast Surg. 1990 Jul;17(3):519-26. Unique Identifier : AIDSLINE MED/90336285
Gallico GG 3d; Harvard Medical School, Boston, Massachusetts.
The absence or loss of skin, because of the resulting drain of fluids and protein and because of the risk of invasive infection, requires wound closure with a skin substitute. Split-thickness skin graft is the gold standard for skin substitutes. Human cadaver allografts are the ideal temporary skin substitute, and the


Usefulness of an antireflux valve in the intensive care unit.
Crit Care Med. 1990 Aug;18(8):878-9. Unique Identifier : AIDSLINE MED/90336359
Shapiro MJ; Minor CB Jr; Keegan M; Department of Surgery, St. Louis University Medical Center, MO; 63110-0250.
The Keith Antireflux Valve (ARV) is a one-way valve placed on the sump port of a double-lumen NG tube. ARV use in critically injured patients significantly prevents reflux through the sump port and decreases the incidence of both patient gown and linen change and NG tube repositioning. There is no evidence to indicate


Recombinant HIV2 protease processes HIV1 Pr53gag and analogous junction peptides in vitro.
J Biol Chem. 1990 Aug 15;265(23):13890-8. Unique Identifier : AIDSLINE MED/90338008
Pichuantes S; Babe LM; Barr PJ; DeCamp DL; Craik CS; Department of Pharmaceutical Chemistry, University of California; San Francisco 94143.
A synthetic DNA fragment encoding a protease precursor of the human immunodeficiency virus type 2 (HIV2) was cloned and expressed in bacteria and yeast. A recombinant plasmid encoding a hybrid polypeptide consisting of human superoxide dismutase and an HIV2 protease precursor of 113 amino acids was constructed for reg


Serological evaluation of Escherichia coli-expressed human T-cell leukemia virus type I env, gag p24, and tax proteins.
J Clin Microbiol. 1990 Jun;28(6):1139-42. Unique Identifier : AIDSLINE MED/90338346
Coates SR; Harris AJ; Parkes DL; Smith CM; Liu HL; Akita RW; Ferrer MM; Sampson EK; Brandis JW; Sliwkowski MX; Triton Biosciences Inc., Alameda, California 94501.
Three proteins (env, gag, and tax) encoded by the human T-cell leukemia virus type I (HTLV-I) genome were cloned and expressed in Escherichia coli. The env protein contained a substantial part of the gp46 domain and a majority of the p21e domain. The gag protein contained all of p24 and portions of p19 and p15. In add


Evaluation of a human immunodeficiency virus test algorithm utilizing a recombinant protein enzyme immunoassay.
J Clin Microbiol. 1990 Jun;28(6):1169-71. Unique Identifier : AIDSLINE MED/90338352
Lepine DG; Neumann PW; Frenette SL; O'Shaughnessy MV; Bureau of Laboratories and Research, Federal Centre for AIDS,; Ottawa, Ontario, Canada.
Many truly human immunodeficiency virus (HIV) antibody-negative serum samples may be unnecessarily subjected to costly and time-consuming Western blots (immunoblots). An investigation was undertaken to evaluate the efficiency of using a recombinant protein-based enzyme immunosorbent assay (EIA; Cambridge BioScience [C


Expression of basic fibroblast growth factor (bFGF) in Kaposi's sarcoma: an immunohistologic study.
J Invest Dermatol. 1990 Aug;95(2):238-40. Unique Identifier : AIDSLINE MED/90338810
Schulze-Osthoff K; Goerdt S; Sorg C; Institute of Experimental Dermatology, University of Munster,; F.R.G.
Ten cases of Kaposi s sarcoma (KS) including five AIDS-KS, one classical KS, and four pseudo-KS (acroangiodermatitis) were investigated for their expression of basic fibroblast growth factor. Antigen expression was demonstrated by immunoperoxidase staining of cryostat sections with affinity-purified anti-bFGF antibodi


Pefloxacin in the antibacterial treatment of immunodepressed patients.
J Chemother. 1990 Jun;2(3):185-9. Unique Identifier : AIDSLINE MED/90339119
Cajozzo A; Carbone R; Carotenuto M; Grana M; La Sala A; Mancuso S; Perricone R; Sgalambro A; Dammacco F; Istituto di Clinica Medica e Malattie Cardiovascolari,; Universita di Palermo, Italy.
Pefloxacin 800 to 1200 mg daily was given for 3 to 20 days, orally or intravenously, to 84 immunocompromised patients. Five patients dropped out because of side effects and 2 for other causes. Treatment efficacy was evaluated in 77 patients, 43 men and 34 women, aged 18 to 80 years. Immunodepression resulted from mali


Synergistic activation of transcription by multiple binding sites for NF-kappa B even in absence of co-operative factor binding to DNA.
J Mol Biol. 1990 Jul 20;214(2):373-80. Unique Identifier : AIDSLINE MED/90339482
Pettersson M; Schaffner W; Institut fur Molekularbiologie II, Universitat Zurich,; Switzerland.
Regulation of eukaryotic genes is largely governed by multiple cis-acting DNA sequences recognized by specific transcription factors. The transcription factor NF-kappa B has been implicated as an important regulator of cellular and viral genes, including those of immunoglobulin kappa light chain, interleukin-2, beta-i


[The monocyte-macrophage system and acquired immunodeficiency syndrome (AIDS)]
Medicina (Firenze). 1990 Jan-Mar;10(1):1-8. Unique Identifier : AIDSLINE MED/90339969
Ercoli L; Perno CF; Bergamini A; Rocchi G; Dipartimento di Sanita Pubblica e Biologia Cellulare,; Universita degli Studi di Roma, Tor Vergata.
The pathogenesis of HIV infection and the definition of the cell types target of HIV is the crucial background for the improvement of the therapeutic strategies against HIV infection. Monocyte-macrophages (M/M) are easily infected by HIV, and play a crucial role in the maintenance and the progression of HIV-related di


Voluntary HIV antibody testing among STD clinic patients: a pilot study.
Med J Aust. 1990 Jul 2;153(1):12-4. Unique Identifier : AIDSLINE MED/90340187
McDonald AM; Whyte BM; Jacobs D; Philpot CR; Bradford DL; Monheit B; James ML; Goulden T; Cooper DA; Kaldor JM; National Centre in HIV Epidemiology and Clinical Research,; University of New South Wales.
A pilot study was conducted with the aim of measuring the acceptability of voluntary testing for human immunodeficiency virus (HIV) antibody among patients attending sexually transmissible disease (STD) clinics. Three STD clinics, two public and one private, participated in the study which was conducted over a three-m


New rules for new drugs: the challenge of AIDS to the regulatory process.
Milbank Q. 1990;68 Suppl 1:111-42. Unique Identifier : AIDSLINE MED/90340232
Edgar H; Rothman DJ; Columbia University.
AIDS is systematically changing attitudes and practices regarding the regulation and use of drugs. The complex framework and rigorous research protocols developed by the Food and Drug Administration prior to the 1980s to minimize risk to subjects is shifting in the epidemic s wake to maximize innovation. The


AIDS scan. WHO issues new estimates of HIV/AIDS by the year 2000.
Nurs RSA. 1990 May;5(5):41-2. Unique Identifier : AIDSLINE MED/90340388
The medical evaluation of the sexually abused child.
Pediatr Clin North Am. 1990 Aug;37(4):839-62. Unique Identifier : AIDSLINE MED/90340908
Paradise JE; Boston University School of Medicine, Massachusetts.
The diagnosis of suspected sexual abuse is nearly always based on a description of abuse provided by the child. The physician should invite a child to describe his or her sexual victimization in detail if such a disclosure interview has not already occurred, if the child seems ready to describe the abuse, and if a chi


Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease.
Science. 1990 Aug 3;249(4968):527-33. Unique Identifier : AIDSLINE MED/90341771
Erickson J; Neidhart DJ; VanDrie J; Kempf DJ; Wang XC; Norbeck DW; Plattner JJ; Rittenhouse JW; Turon M; Wideburg N; et al; Department of Computer-Assisted Molecular Design, Abbott; Laboratories, Abbott Park, IL 60064.
A two-fold (C2) symmetric inhibitor of the protease of human immunodeficiency virus type-1 (HIV-1) has been designed on the basis of the three-dimensional symmetry of the enzyme active site. The symmetric molecule inhibited both protease activity and acute HIV-1 infection in vitro, was at least 10,000-fold more potent


Specific tropism of HIV-1 for microglial cells in primary human brain cultures.
Science. 1990 Aug 3;249(4968):549-53. Unique Identifier : AIDSLINE MED/90341777
Watkins BA; Dorn HH; Kelly WB; Armstrong RC; Potts BJ; Michaels F; Kufta CV; Dubois-Dalcq M; Laboratory of Viral and Molecular Pathogenesis, National; Institute of Neurological Disorders and Stroke, National; Institutes of Health, Bethesda, MD 20892.
Human immunodeficiency virus (HIV) frequently causes neurological dysfunction and is abundantly expressed in the central nervous system (CNS) of acquired immunodeficiency syndrome (AIDS) patients with HIV encephalitis or myelopathy. The virus is found mostly in cells of the monocyte-macrophage lineage within the CNS,


Zidovudine for the treatment of HIV infection [see comments]
Am Fam Physician. 1990 Aug;42(2):437-43. Unique Identifier : AIDSLINE MED/90342672
Pepe R; Molavi A; Division of Infectious Diseases, Hahneman University School of; Medicine, Philadelphia, Pennsylvania.
Zidovudine, the first widely used antiretroviral agent, prevents replication of the human immunodeficiency virus (HIV) by inhibiting reverse transcriptase. Its use in patients with acquired immunodeficiency syndrome slows progression of the disease and prolongs survival. Zidovudine also significantly reduces the rate


Varicella-zoster virus disease in patients with human immunodeficiency virus infection [comment]
Arch Dermatol. 1990 Aug;126(8):1086-8. Unique Identifier : AIDSLINE MED/90343389
Gulick RM; Heath-Chiozzi M; Crumpacker CS; Department of Infectious Diseases, Beth Israel Hospital, Boston,; MA 02215.
Nutritional aspects of AIDS.
Annu Rev Nutr. 1990;10:475-501. Unique Identifier : AIDSLINE MED/90344350
Keusch GT; Farthing MJ; Division of Geographic Medicine and Infectious Diseases, New; England Medical Center Hospital, Tufts University School of; Medicine, Boston, Massachusetts 02111.
Quantitative aspects of septicemia.
Clin Microbiol Rev. 1990 Jul;3(3):269-79. Unique Identifier : AIDSLINE MED/90345400
Yagupsky P; Nolte FS; Department of Microbiology and Immunology, University of; Rochester Medical Center, New York 14642.
For years, quantitative blood cultures found only limited use as aids in the diagnosis and management of septic patients because the available methods were cumbersome, labor intensive, and practical only for relatively small volumes of blood. The development and subsequent commercial availability of lysis-centrifugati


Expression of human immunodeficiency virus long terminal repeat in the human promonocyte cell line U937: effect of endotoxin and cytokines.
Cell Immunol. 1990 Sep;129(2):513-8. Unique Identifier : AIDSLINE MED/90345469
Latham PS; Lewis AM; Varesio L; Pavlakis GN; Felber BK; Ruscetti FW; Young HA; Laboratory of Molecular Immunobiology, National Cancer Institute,; Frederick Cancer Research Facility, Maryland 21701.
Phagocytic macrophages are known to support noncytopathic, chronic infections of human immunodeficiency virus (HIV). Regulation of viral replication in such cells with either chronic low-grade or latent HIV infection is probably influenced by both viral and cellular factors acting on the viral long terminal repeat (LT


Group G streptococcal meningitis and sepsis in a patient with AIDS. A method to biotype group G streptococcus.
Diagn Microbiol Infect Dis. 1990 May-Jun;13(3):261-4. Unique Identifier : AIDSLINE MED/90345623
Raviglione MC; Tierno PM; Ottuso P; Klemes AB; Davidson M; Department of Medicine, Cabrini Medical Center, New York, New; York 10003.
Lancefield group G streptococcus is now recognized as a pathogen and has been reported to cause severe infections, including meningitis. We describe the first case of meningitis caused by this organism in a patient with acquired immunodeficiency syndrome (AIDS) and the direct transmission of the pathogen to a technolo


Recent developments in sexually transmitted diseases: is heterosexual transmission of HIV a major epidemiologic factor in the spread of AIDS? New York City's experience.
Cutis. 1990 Jul;46(1):29-31. Unique Identifier : AIDSLINE MED/90345730
Felman YM; Downstate Medical School, Brooklyn, New York.
Sub-site preferences of the aspartic proteinase from the human immunodeficiency virus, HIV-1.
FEBS Lett. 1990 Jul 30;268(1):35-8. Unique Identifier : AIDSLINE MED/90346166
Konvalinka J; Strop P; Velek J; Cerna V; Kostka V; Phylip LH; Richards AD; Dunn BM; Kay J; Institute of Organic Chemistry and Biochemistry, Czechoslovak; Academy of Science, Praha.
A series of synthetic, chromogenic substrates for HIV-1 proteinase with the general structure Ala-Thr-His-Xaa-Yaa-Zaa*Nph-Val-Arg-Lys-Ala was synthesised with a variety of residues introduced into the Xaa, Yaa and Zaa positions. Kinetics parameters for hydrolysis of each peptide by HIV-1 proteinase at pH 4.7, 37 degre


Response of monkeys to vaccination with recombinant vaccinia virus which coexpress HIV gp160 and human interleukin-2.
Immunol Cell Biol. 1990 Apr;68 ( Pt 2):113-7. Unique Identifier : AIDSLINE MED/90346408
Ruby J; Brinkman C; Jones S; Ramshaw I; Division of Cell Biology, John Curtin School of Medical Research,; Australian National University, Canberra.
Immunization of two macaque monkeys with recombinant vaccinia viruses encoding the env gene of HIV-1 (VV-gp160) resulted in demonstrable levels of gp160, gp120 and gp41-specific immunoglobulins in both animals. The virus used to immunize one of the monkeys additionally expressed the human


Titration of human immunodeficiency virus type 1 (HIV-1) and quantitative analysis of virus expression in vitro using liquid RNA-RNA hybridization.
J Virol Methods. 1990 Jun;28(3):257-71. Unique Identifier : AIDSLINE MED/90347024
Volsky DJ; Pellegrino MG; Li G; Logan KA; Aswell JE; Lawrence NP; Decker SR; Molecular Virology Laboratory, St. Luke's/Roosevelt Hospital; Center, Columbia University, New York, New York.
An assay is described for titration of human immunodeficiency virus type 1 (HIV-1) and for quantitative analysis of virus expression in vitro. The assay utilizes a liquid RNA-RNA hybridization method coupled with reversible target capture (RTC) on oligo(dT) derivatized magnetic particles. The assay provides a rapid, s


Once-weekly fluconazole to prevent recurrence of oropharyngeal candidiasis in patients with AIDS and AIDS-related complex: a double-blind placebo-controlled study [published erratum appears in J Infect 1990 Sep;21(2):183]
J Infect. 1990 Jul;21(1):55-60. Unique Identifier : AIDSLINE MED/90347235
Leen CL; Dunbar EM; Ellis ME; Mandal BK; Regional Department of Infectious Diseases and Tropical Medicine,; Monsall Hospital, Manchester, U.K.
Fluconazole 50 mg daily for 14-28 days was effective in the treatment of patients with AIDS and AIDS-related complex with severe oropharyngeal and oesophageal candidiasis. Of 24 patients entered, 17 (81%), including seven with oesophageal candidiasis, were clinically cured and two (9.5%) improved at the end of treatme


Influence of human immunodeficiency virus infection on treponemal serology, in patients who have been treated for syphilis.
J Infect. 1990 Jul;21(1):95-103. Unique Identifier : AIDSLINE MED/90347242
McMillan A; Young H; Peutherer JF; Department of Genito-Urinary Medicine, Edinburgh Royal Infirmary,; Scotland, U.K.
Sera from 20 homosexual men who were infected with the human immunodeficiency virus (HIV) and had been treated previously for syphilis, were examined for cardiolipin and treponemal antibodies by the Venereal Diseases Research Laboratory (VDRL) test, and the Treponema pallidum haemagglutination assay (TPHA) and fluores


Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells.
J Virol. 1990 Sep;64(9):4306-12. Unique Identifier : AIDSLINE MED/90347825
Kinter AL; Poli G; Maury W; Folks TM; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, Bethesda, Maryland 20892.
The chronically infected promonocytic clone U1 expresses low-to-undetectable constitutive levels of human immunodeficiency virus (HIV). Virus replication in these cells can be increased up to 25-fold by phorbol esters (phorbol-12-myristate-13-acetate), recombinant cytokines such as tumor necrosis factor-alpha, and cyt


Structural role of the matrix protein of type D retroviruses in gag polyprotein stability and capsid assembly.
J Virol. 1990 Sep;64(9):4383-9. Unique Identifier : AIDSLINE MED/90347834
Rhee SS; Hunter E; Department of Microbiology, University of Alabama, Birmingham; 35294.
To obtain a better understanding of the role of the gag gene-encoded matrix (MA) protein in the assembly and maturation of type D retroviruses, we have made five mutants with specific in-frame deletions within the p10-coding region by the use of oligonucleotide-directed mutagenesis. The changes in the Gag polyprotein


Function of the human immunodeficiency virus types 1 and 2 Rev proteins is dependent on their ability to interact with a structured region present in env gene mRNA.
J Virol. 1990 Sep;64(9):4428-37. Unique Identifier : AIDSLINE MED/90347840
Dillon PJ; Nelbock P; Perkins A; Rosen CA; Department of Molecular Oncology and Virology, Roche Research; Center, Nutley, New Jersey 07110-1199.
The interaction of the human immunodeficiency virus type 1 (HIV-1) Rev protein with a structured region in env mRNA (the Rev-responsive element [RRE]) mediates the export of structural mRNAs from the nucleus to the cytoplasm. We demonstrated that unlike HIV-1 Rev, which functions with both the HIV-1 and HIV-2 RREs, HI


Macrophage-tropic strains of human immunodeficiency virus type 1 utilize the CD4 receptor.
J Virol. 1990 Sep;64(9):4468-76. Unique Identifier : AIDSLINE MED/90347845
Collman R; Godfrey B; Cutilli J; Rhodes A; Hassan NF; Sweet R; Douglas SD; Friedman H; Nathanson N; Gonzalez-Scarano F; Department of Medicine, University of Pennsylvania Medical; Center, Philadelphia.
To characterize the role of CD4 in human immunodeficiency virus type 1 (HIV-1) infection of macrophages, we examined the expression of CD4 by primary human monocyte-derived macrophages and studied the effect of recombinant soluble CD4 and anti-CD4 monoclonal antibodies on HIV-1 infection of these cells. Immunofluoresc


Human chromosome 12 encodes a species-specific factor which increases human immunodeficiency virus type 1 tat-mediated trans activation in rodent cells.
J Virol. 1990 Sep;64(9):4565-7. Unique Identifier : AIDSLINE MED/90347857
Newstein M; Stanbridge EJ; Casey G; Shank PR; Division of Biology and Medicine, Brown University, Providence,; Rhode Island 02912.
The human immunodeficiency virus type 1 (HIV-1) tat protein functions at a much lower level in rodent cells than in human cells. This species-specific difference in trans activation appears to be due to the lack of a functional homolog of a human cofactor for tat in rodent cells. Using HIV-1 long terminal repeat-drive


Preleukemic hematopoietic hyperplasia induced by Moloney murine leukemia virus is an indirect consequence of viral infection.
J Virol. 1990 Sep;64(9):4582-4. Unique Identifier : AIDSLINE MED/90347861
Brightman BK; Davis BR; Fan H; Department of Molecular Biology and Biochemistry, University of; California, Irvine 92717.
We previously showed that neonatal mice inoculated with Moloney murine leukemia virus (M-MuLV) exhibit a preleukemic state characterized by splenomegaly and increased numbers of hematopoietic progenitors. An M-MuLV variant with greatly reduced leukemogenic potential, Mo+PyF101 M-MuLV, does not generally induce this pr


[Rheumatological aspects of infection with human immunodeficiency virus (HIV)]
Med Trop (Mars). 1990 Apr;50(2):231-5. Unique Identifier : AIDSLINE MED/90348463
Jeandel P; Chouc PY; Laroche R; Institut de Medicine Tropicale, Service de Sante des Armees le; Pharo Marseille.
Since 1987, some works have been devoted to rheumatological manifestations appearing during the course of the HIV infection. If neurotropism of this retrovirus explains some misleading pseudo radicular aspects of the disease, sometimes revealing, inflammatory neuro-arthropathies are still under discussion. In Tropical


Nucleotide sequence analysis of a provirus derived from an individual with tropical spastic paraparesis.
Microb Pathog. 1990 Apr;8(4):259-78. Unique Identifier : AIDSLINE MED/90348469
Evangelista A; Maroushek S; Minnigan H; Larson A; Retzel E; Haase A; Gonzalez-Dunia D; McFarlin D; Mingioli E; Jacobson S; et al; Department of Microbiology, University of Minnesota Medical; School, Minneapolis 55455.
Human T-cell lymphotropic virus type 1 (HTLV-1), the cause of inapparent infections and T-cell leukemias and lymphomas, has also been implicated in two chronic neurological diseases, tropical spastic paraparesis (TSP) and HTLV-1 associated myelopathy (HAM). We initiated a search for a neurotropic variant of HTLV-1 tha


Severe streptococcal axillary lymphadenitis.
N Engl J Med. 1990 Sep 6;323(10):655-8. Unique Identifier : AIDSLINE MED/90348730
Boyce JM; Department of Medicine, Miriam Hospital, Providence, RI 02906.
Human immunodeficiency virus type 1 protease cleaves the intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein.
Proc Natl Acad Sci U S A. 1990 Aug;87(16):6336-40. Unique Identifier : AIDSLINE MED/90349610
Shoeman RL; Honer B; Stoller TJ; Kesselmeier C; Miedel MC; Traub P; Graves MC; Max-Planck-Institut fur Zellbiologie, Abteilung Traub, Rosenhof,; Federal Republic of Germany.
The intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein are cleaved in vitro by human immunodeficiency virus type 1 protease (HIV-1 PR). Microsequencing showed that HIV-1 PR cleaved both human and murine vimentin between leucine-422 and arginine-423 within the sequence between position


Infectious diseases of geriatric inmates.
Rev Infect Dis. 1990 Jul-Aug;12(4):683-92. Unique Identifier : AIDSLINE MED/90349962
Glaser JB; Warchol A; D'Angelo D; Guterman H; Department of Medicine, Staten Island Hospital, New York.
The number of geriatric inmates is rapidly growing because of more frequent incarceration of older offenders as the number of the elderly in the general population increases nationally. The increase is also due to recent changes in sentencing patterns (e.g., longer sentences and tightened parole) that affect younger,


Syphilis serology in human immunodeficiency virus-infected patients with symptomatic neurosyphilis: case report and review.
Rev Infect Dis. 1990 Jul-Aug;12(4):703-7. Unique Identifier : AIDSLINE MED/90349964
Matlow AG; Rachlis AR; Department of Microbiology, Hospital for Sick Children, Toronto,; Ontario, Canada.
The clinical and serologic diagnosis of syphilis in the human immunodeficiency virus-infected patient may be difficult to make. We have recently seen a case of symptomatic neurosyphilis in such a patient presenting with positive serum and CSF syphilis serology. On the basis of this case and similar cases reported in t


Zidovudine intolerance.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S500-6. Unique Identifier : AIDSLINE MED/90349970
Groopman JE; Division of Hematology/Oncology, New England Deaconess Hospital,; Boston, Massachusetts 02215.
Patients may be intolerant of zidovudine for several reasons, the most prominent being hematologic toxicity. In vitro studies demonstrate that zidovudine is toxic to the myeloid and erythroid precursors in the bone marrow; at concentrations of zidovudine near those associated with the optimal antiviral effect in vitro


Zidovudine resistance of human immunodeficiency virus [see comments]
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S507-10; discussion S510-2. Unique Identifier : AIDSLINE MED/90349971
Richman DD; Department of Pathology, University of California, San Diego.
The observation that human immunodeficiency virus resistant to zidovudine can be isolated from patients with AIDS or AIDS-related complex during prolonged zidovudine treatment was made with a plaque reduction assay employing a CD4-expressing HeLa cell line. Fifty percent inhibitory concentrations of zidovudine for iso


Considerations for the evaluation of antiretroviral agents in infants and children infected with human immunodeficiency virus: a perspective from the National Cancer Institute.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S561-9. Unique Identifier : AIDSLINE MED/90349977
Pizzo PA; Pediatric Branch, National Cancer Institute, National Institutes; of Health, Bethesda, Maryland 20892.
Human immunodeficiency virus (HIV) infection in infants and young children differs in a number of ways from that in adults. In most HIV-infected children the infection is acquired perinatally and the course of infection is more accelerated than in adults. Diseases related to B cell defects and dysgammaglobulinemia (e.


Treatment of chancroid, 1989.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 6:S580-9. Unique Identifier : AIDSLINE MED/90349981
Schmid GP; Division of STD/HIV Prevention, Centers for Disease Control,; Atlanta, Georgia 30333.
Since recommendations for the treatment of chancroid were made in 1985, in vitro and in vivo data indicate that the two drugs recommended, erythromycin (500 mg four times a day for 7 days) and ceftriaxone (250 mg intramuscularly in a single dose), remain effective. The alternative therapies of trimethoprim-sulfamethox


Treatment of syphilis, 1989.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 6:S590-609. Unique Identifier : AIDSLINE MED/90349982
Zenker PN; Rolfs RT; Division of STD/HIV Prevention, Centers for Disease Control,; Atlanta, Georgia 30333.
With the introduction of penicillin after World War II, the incidence of syphilis in the United States decreased. Because of penicillin s great success, clinical trials stopped after an initial period of intensive investigation. Syphilis is a difficult disease to study; the natural his


Sexual assault and sexually transmitted diseases: detection and management in adults and children.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 6:S682-90. Unique Identifier : AIDSLINE MED/90349989
Schwarcz SK; Whittington WL; Division of Sexually Transmitted Diseases, Centers for Disease; Control, Atlanta, Georgia 30333.
Sexual assault is a frequently occurring violent crime. Sexually transmitted diseases (STDs) may be acquired during assault. Reported rates of gonorrhea and syphilis in adult victims range from 6% to 12% and from 0% to 3%, respectively. The risk of acquiring other STDs cannot be quantified, although the risk of infect


Opportunistic infections in AIDS in developed and developing countries.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:1-6. Unique Identifier : AIDSLINE MED/90350166
Fleming AF; Department of Medicine and Infectious Diseases, Liverpool School; of Tropical Medicine, UK.
The acquired immune deficiency syndrome (AIDS) is fundamentally the same disease in all parts of the world, but the prevalence of microorganisms in an environment governs the patterns of disease arising from reactivated latent infections, invading pathogens and opportunistic infections. AIDS in Africa has certain char


Septicaemia in patients with AIDS.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:14-6. Unique Identifier : AIDSLINE MED/90350167
Shanson DC; Department of Medical Microbiology, Charing Cross and Westminster; Medical School, London, UK.
During a 5 year period at St Stephen s hospital, London, septicaemia was detected in 66 patients with the acquired immune deficiency syndrome (AIDS) and in 13 other patients with non-AIDS-associated HIV infections. The most frequent pathogens in patients with AIDS were Mycobacterium avium-intracellulare, Streptococcus


Protozoan infections.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:19-24. Unique Identifier : AIDSLINE MED/90350169
Canning EU; Imperial College of Science, Technology and Medicine, London, UK.
Protozoan infections, against which immunity is predominantly T cell mediated, are likely to be more severe in patients with the acquired immune deficiency syndrome (AIDS) than in immunocompetent hosts. Leishmaniasis, toxoplasmosis and cryptosporidiosis are examples, the last two being particularly common in AIDS pati


Problems of chemotherapy in multiply-infected AIDS patients.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:25-33. Unique Identifier : AIDSLINE MED/90350170
Gazzard BG; Westminster Hospital, London, UK.
Potential multiple opportunistic infections in patients with the acquired immune deficiency syndrome (AIDS) cause the clinician considerable problems. Firstly there is the problem of the correct diagnosis of which organism is producing symptoms and there is the possibility of more than one organism being responsible.


Missing infections in AIDS.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:34-8. Unique Identifier : AIDSLINE MED/90350171
Lucas SB; Department of Histopathology, University College and Middlesex; School of Medicine, London, UK.
In north America and Europe, the opportunistic infections from which patients with acquired immune deficiency syndrome (AIDS) frequently suffer are Pneumocystis carinii pneumonia and Mycobacterium avium-intracellulare: in central Africa these infections are uncommon or non-existent. Serious infections with Entamoeba h


Virus infections in patients with AIDS.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:7-8. Unique Identifier : AIDSLINE MED/90350172
Griffiths PD; Department of Virology, Royal Free Hospital School of Medicine,; Hampstead, London, UK.
Virus infections are common in patients with acquired immune deficiency syndrome (AIDS). Viruses can have two distinct relationships with human immunodeficiency virus (HIV); they can be opportunists if the second virus takes advantage of decreased immune function in the host or they can act as co-factors to accelerate


Impact of human immunodeficiency virus on transmission and severity of tuberculosis.
Trans R Soc Trop Med Hyg. 1990;84 Suppl 1:9-13. Unique Identifier : AIDSLINE MED/90350173
Nunn P; Kibuga D; Elliott A; Gathua S; Respiratory Disease Research Centre, Kenya Medical Research; Institute, Nairobi.
It is now clear that tuberculosis is one of the major diseases associated with human immunodeficiency virus (HIV) infection and the acquired immune deficiency syndrome both in developing countries and in disadvantaged groups in the northern hemisphere. In the USA, and probably several other countries, the annual incid


Bibliography of the current world literature.
AIDS. 1990 Jun;4(6):A31-7. Unique Identifier : AIDSLINE MED/90351560
Application of flow cytometry to the study of HIV infection.
AIDS. 1990 Jun;4(6):479-97. Unique Identifier : AIDSLINE MED/90351561
Landay A; Ohlsson-Wilhelm B; Giorgi JV; Department of Immunology/Microbiology, Medicine and Pathology,; Rush Presbyterian St Luke's Medical Center, Chicago, Illinois; 60612.
Tat and Rev: positive regulators of HIV gene expression [published erratum appears in AIDS 1990 Aug;4(8):following A48]
AIDS. 1990 Jun;4(6):499-509. Unique Identifier : AIDSLINE MED/90351562
Rosen CA; Pavlakis GN; Department of Oncology and Virology, Roche Institute of Molecular; Biology, NNutley, New Jersey.
Infection of human fibroblasts and osteoblast-like cells with HIV-1.
AIDS. 1990 Jun;4(6):527-35. Unique Identifier : AIDSLINE MED/90351566
Mellert W; Kleinschmidt A; Schmidt J; Festl H; Emler S; Roth WK; Erfle V; Abteilung fur Molekulare Zellpathologie, Gesellschaft fur; Strahlen- und Umweltforschung Munchen (GSF), Neuherberg, FRG.
Primary human skin- and lung-derived fibroblast cell cultures and continuous human osteoblast-like and fibroblast-like cell lines were infected with different strains of HIV-1. Infection was measured at the single-cell level using the immunoperoxidase staining method to detect viral proteins. No cytopathic effects wer


Immunogenicity and antigenicity of conserved peptides from the envelope of HIV-1 expressed at the surface of recombinant bacteria.
AIDS. 1990 Jun;4(6):545-51. Unique Identifier : AIDSLINE MED/90351568
Charbit A; Molla A; Ronco J; Clement JM; Favier V; Bahraoui EM; Montagnier L; Leguern A; Hofnung M; Unite de Programmation Moleculaire et Toxicologie Genetique; (CNRS UA271, INSERM U163), Paris, France.
We expressed peptides from the HIV-1 envelope protein at the surface of Escherichia coli by genetic insertions into an exposed loop of the outer membrane protein LamB. Recombinant bacteria expressing eight peptides from gp110 (pep1-pep8), conserved between HIV-1 and HIV-2, were used as live immunogens in rabbits by th


Characterization of the African HIV-1 isolate CBL-4 (RUT) by partial sequence analysis and virus neutralization with peptide antibody and antisense phosphate-methylated DNA [published errata appear in AIDS 1990 Jul;4(7):following A44 and 1990 Dec;4(12):A72]
AIDS. 1990 Jun;4(6):559-64. Unique Identifier : AIDSLINE MED/90351570
Goudsmit J; Geelen J; Keulen W; Notermans D; Kuiken C; Ramautarsing C; Smit L; Koole L; van Genderen M; Buck H; et al; Human Retrovirus Laboratory, Academic Medical Center, University; of Amsterdam, The Netherlands.
The HIV-1 isolate CBL-4 (RUT), originating from Tanzania , was characterized using a comprehensive virus-typing system. This system included sequence analysis of the region coding for the neutralization domain in the third variable region (V3) of the external envelope and of the t


Treatment with bovine hyperimmune colostrum of cryptosporidial diarrhea in AIDS patients.
AIDS. 1990 Jun;4(6):581-4. Unique Identifier : AIDSLINE MED/90351575
Nord J; Ma P; DiJohn D; Tzipori S; Tacket CO; St Vincent's Hospital and Medical Center, New York.
Cryptosporidium parvum may cause severe, debilitating diarrhea in patients with AIDS. Recent anecdotal reports have suggested that hyperimmune bovine colostrum may be effective. We conducted a double-blind, controlled pilot study of hyperimmune bovine colostrum for diarrhea due to cryptosporidiosis in five AIDS patien


The significance of 'no significant difference'.
Acta Radiol. 1990 May;31(3):315-8. Unique Identifier : AIDSLINE MED/90351683
Brismar J; Jacobsson B; Department of Radiology, King Faisal Specialist Hospital and; Research Centre, Riyadh, Saudi Arabia.
It is generally accepted that patients experience less discomfort with low osmolality contrast media (LOM) than with high osmolar media (HOM). Hard statistical facts from so called high quality controlled trials, proving that more significant reactions such as vomiting, hives, urticaria or anaphylactic complications


Assessment of knowledge of AIDS and beliefs about AIDS prevention among adolescents.
AIDS Educ Prev. 1990 Spring;2(1):58-69. Unique Identifier : AIDSLINE MED/90351747
Koopman C; Rotherman-Borus MJ; Henderson R; Bradley JS; Hunter J; Division of Child Psychiatry, Columbia University, New York, NY; 10032.
This report describes the development of measures of AIDS knowledge and beliefs about AIDS prevention for adolescents. Review of the literature, focus groups, pilot testing, and reviews by advisory councils assured that the process of developing the measures contributed to their validity. These measures were administe


Chromosomal translocations in lymphoid neoplasia: a reappraisal of the recombinase model.
Cancer Cells. 1990 Jan;2(1):1-8. Unique Identifier : AIDSLINE MED/90351784
Tycko B; Sklar J; Harvard Medical School.
Chromosomal translocations are common in tumors and are considered to represent one of the major classes of genetic alterations productive of the malignant phenotype. Although the molecular mechanisms leading to translocations are unknown, structural analysis of translocations in tumors derived from lymphocytes and th


Neuroimaging in various stages of human immunodeficiency virus infection.
Curr Opin Radiol. 1990 Feb;2(1):73-9. Unique Identifier : AIDSLINE MED/90351852
Post MJ; University of Miami School of Medicine, Florida.
Thoracic infections.
Curr Opin Radiol. 1990 Jun;2(3):351-4. Unique Identifier : AIDSLINE MED/90351856
Conces DJ Jr; Indiana University Medical Center, Indianapolis.
Imaging of the gastrointestinal tract in the acquired immunodeficiency syndrome.
Curr Opin Radiol. 1990 Jun;2(3):467-71. Unique Identifier : AIDSLINE MED/90351872
Jeffrey RB Jr; Stanford University Medical Center, California.
Epidemiology and immunovirology of human T-cell leukemia/lymphoma virus type I-associated adult T-cell leukemia and chronic myelopathies as seen in France.
Cancer Res. 1990 Sep 1;50(17 Suppl):5692S-5696S. Unique Identifier : AIDSLINE MED/90352627
Gessain A; Gout O; Saal F; Daniel MT; Rio B; Flandrin G; Sigaux F; Lyon-Caen O; Peries J; de-The G; CNRS Laboratory of Epidemiology and Immunovirology of Tumors,; Faculte de Medicine Alexis Carrel, Lyon, France.
Seventeen patients with adult T-cell leukemia (ATL) and 21 with tropical spastic paraparesis/human T-cell leukemia/lymphoma virus type I (HTLV-I)-associated myelopathy (TSP/HAM) were observed during a 3-yr survey (1986-1988) in some hospitals in Paris, France . Most of them were bla


Characterization of AIDS-associated tumors in Italy: report of 435 cases of an IVDA-based series.
Cancer Detect Prev. 1990;14(3):391-3. Unique Identifier : AIDSLINE MED/90352644
Monfardini S; Vaccher E; Lazzarin A; Rezza G; Alessi E; Baroni C; Bernasconi C; Carbone A; Luzi G; Mandelli F; et al; Gruppo Italiano Cooperativo AIDS et Tumori.
The Italian Cooperative Group on AIDS-related tumors has collected 435 cases of HIV-associated tumors since December 1986. The following conclusions can be drawn from this IVDA-based series: (1) at least 15% of AIDS cases are associated with tumors; (2) the number of malignant lymphomas (high-grade


Treatment of AIDS-associated malignancy.
Cancer Detect Prev. 1990;14(3):405-9. Unique Identifier : AIDSLINE MED/90352647
Krown SE; Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
Neoplasms associated with acquired immunodeficiency syndrome (AIDS) present unique therapeutic challenges. High-grade systemic lymphomas, although often responsive to standard chemotherapy, will require the addition of CSFs, infection prophylaxis, and antiretroviral drugs to overcome poor marrow reserves, short respon


Oral manifestations of HIV infection, Part II: Viral infections and neoplastic lesions.
Compendium. 1990 Apr;11(4):236, 238, 240-3. Unique Identifier : AIDSLINE MED/90352679
Haring JI; Ohio State University College of Dentistry.
The dental practitioner is in a unique position to detect the early signs of HIV infection that appear in the mouth. By identifying such lesions, the dentist can contribute to the early diagnosis and timely treatment of HIV-positive individuals. This article, the second of a two-part series, will review the clinical f


TAR-independent activation of the HIV-1 LTR: evidence that tat requires specific regions of the promoter.
Cell. 1990 Aug 24;62(4):757-67. Unique Identifier : AIDSLINE MED/90352709
Berkhout B; Gatignol A; Rabson AB; Jeang KT; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, Maryland 20892.
Replication of HIV-1 requires Tat, which stimulates gene expression through a target sequence, TAR. It is known that TAR is a Tat-responsive target. Since Tat increases transcriptional initiations from the HIV-1 LTR promoter, it is unclear mechanistically how Tat utilizes an RNA target. Here we show that TAR RNA is on


HIV promoter activity in primary antigen-specific human T lymphocytes.
Dis Markers. 1990 Mar-Apr;8(2):104-5. Unique Identifier : AIDSLINE MED/90352915
Activity of synthetic peptides from the Tat protein of human immunodeficiency virus type 1.
Dis Markers. 1990 Mar-Apr;8(2):107. Unique Identifier : AIDSLINE MED/90352917
The impact of drug abuse and addiction on society.
Emerg Med Clin North Am. 1990 Aug;8(3):467-80. Unique Identifier : AIDSLINE MED/90353215
Hoffman RS; Goldfrank LR; New York City Poison Control Center, New York.
Over 28 million Americans have admitted to abusing a substance in the last year alone, at a direct purchase price of over 79 billion dollars. Substance abuse and addiction have grave consequences on our existing social systems, effecting crime rates, hospitalizations, child abuse, and child neglect, and are rapidly co


HIV infection and intravenous drug users. Implications for emergency services.
Emerg Med Clin North Am. 1990 Aug;8(3):653-64. Unique Identifier : AIDSLINE MED/90353227
Kelen GD; Fleetwood D; Department of Emergency Medicine, Johns Hopkins Hospital/Johns; Hopkins University School of Medicine, Baltimore, Maryland.
HIV-1 infection among IVDUs is increasing at a rapid rate in the U.S. Because many Emergency Departments experience many visits from patients with this risk factor, the impact on emergency services can be considerable. Because many of these patients currently have asymptomatic infection, knowledge of clinical presenta


Comparison of inhibitor binding in HIV-1 protease and in non-viral aspartic proteases: the role of the flap.
FEBS Lett. 1990 Aug 20;269(1):269-72. Unique Identifier : AIDSLINE MED/90353592
Gustchina A; Weber IT; Crystallography Laboratory, NCI-Frederick Cancer Research and; Development Center, MD 21701.
The crystal structure of HIV-1 protease with an inhibitor has been compared with the structures of non-viral aspartic proteases complexed with inhibitors. In the dimeric HIV-1 protease, two 4-stranded beta-sheets are formed by half of the inhibitor, residues 27-29, and the flap from each monomer. In the monomeric non-


[Pulmonary manifestations of AIDS]
Harefuah. 1990 Jun 1;118(11):641-3. Unique Identifier : AIDSLINE MED/90353891
Kremer M
[Musculoskeletal manifestations of human immunodeficiency virus infection]
Harefuah. 1990 Jun 1;118(11):644-6. Unique Identifier : AIDSLINE MED/90353892
Buskila D; Lishner M; Sukenik S
Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution.
J Biol Chem. 1990 Aug 25;265(24):14209-19. Unique Identifier : AIDSLINE MED/90354401
Fitzgerald PM; McKeever BM; VanMiddlesworth JF; Springer JP; Heimbach JC; Leu CT; Herber WK; Dixon RA; Darke PL; Department of Biophysical Chemistry, Merck Sharp and Dohme; Research Laboratories, Rahway, New Jersey 07065.
The mode of binding of acetyl-pepstatin to the protease from the human immunodeficiency virus type 1 (HIV-1) has been determined by x-ray diffraction analysis. Crystals of an acetyl-pepstatin-HIV-1 protease complex were obtained in space group P2(1)2(1)2 (unit cell dimensions a = 58.39 A, b = 86.70 A, c = 46.27 A) by


Specificity and inhibition of proteases from human immunodeficiency viruses 1 and 2.
J Biol Chem. 1990 Aug 25;265(24):14675-83. Unique Identifier : AIDSLINE MED/90354468
Tomasselli AG; Hui JO; Sawyer TK; Staples DJ; Bannow C; Reardon IM; Howe WJ; DeCamp DL; Craik CS; Heinrikson RL; Biopolymer Chemistry, Upjohn Company, Kalamazoo, Michigan 49001.
Highly purified, recombinant preparations of the virally encoded proteases from human immunodeficiency viruses (HIV) 1 and 2 have been compared relative to 1) their specificities toward non-viral protein and synthetic peptide substrates, and 2) their inhibition by several P1-P1 pseudodipeptidyl-modified substrate ana


Evidence of widespread binding of HLA class I molecules to peptides.
J Exp Med. 1990 Sep 1;172(3):827-34. Unique Identifier : AIDSLINE MED/90354784
Frelinger JA; Gotch FM; Zweerink H; Wain E; McMichael AJ; Institute of Molecular Medicine, John Radcliffe Hospital,; University of Oxford, United Kingdom.
We have tested the binding of HLA class I proteins to peptides using a solid-phase binding assay. We tested 102 peptides, mostly derived from the HIV gag and HIV pol sequences. Most peptides did not bind to any class I protein tested. The pattern of binding among the three class I proteins tested, HLA-A2, -B27, and -B


The 'Medicaidization' of AIDS. Trends in the financing of HIV-related medical care [see comments]
JAMA. 1990 Sep 12;264(10):1261-6. Unique Identifier : AIDSLINE MED/90355373
Green J; Arno PS; Department of Health Policy Research, New York University Medical; Center, School of Medicine, NY 10016.
Among patients with the acquired immunodeficiency syndrome (AIDS) who were hospitalized in New York City, San Francisco, Calif, and Los Angeles, Calif, from 1983 through 1988, we observed a marked shift in the payer distribution toward Medicaid and away from private insurance. This trend, which we refer to as the Medi


[Morphologic studies in generalized persistent lymphadenopathy syndrome]
Med Clin (Barc). 1990 May 12;94(18):711-6. Unique Identifier : AIDSLINE MED/90355583
Vera-Sempere FJ; Vera-Sempere G; Servicios de Anatomia Patologica (Departamento de Patologia),; Hospital Clinico Universitario, Valencia.
Adolescent wellness. Facilitating compliance in social morbidities.
Med Clin North Am. 1990 Sep;74(5):1135-48. Unique Identifier : AIDSLINE MED/90355608
Rickert VI; Jay MS; Gottlieb AA; Department of Pediatrics, University of Arkansas for Medical; Sciences, Little Rock.
The establishment of a well adolescent schedule needs to be developed similar to the scheduled clinical visits in pediatric care. However, providing adolescent wellness visits without appropriate financial reimbursement for time expended and without increased provider training may make well adolescent visits an unreal


HIV infection and AIDS during adolescence.
Med Clin North Am. 1990 Sep;74(5):1149-67. Unique Identifier : AIDSLINE MED/90355609
Kipke MD; Futterman D; Hein K; University of Southern California School of Medicine, Los; Angeles.
It is clear from the evidence that a growing number of adolescents are acquiring HIV infection and developing AIDS. The impact this epidemic will have on all teenagers is overwhelming. Given the high prevalence of risk-related sexual behaviors, many adolescents are likely to become HIV infected, thus requiring extensi


AIDS testing. Trial approved for saliva test [news]
Nature. 1990 Aug 23;346(6286):687. Unique Identifier : AIDSLINE MED/90356111
Schaefer E
Functions of the auxiliary gene products of the human immunodeficiency virus type 1.
Virology. 1990 Sep;178(1):1-5. Unique Identifier : AIDSLINE MED/90357752
Cullen BR; Greene WC; Howard Hughes Medical Institute, Department of Microbiology and; Immunology, Duke University Medical Center, Durham, North; Carolina 27710.
Mutants in a conserved region near the carboxy-terminus of HIV-1 Rev identify functionally important residues and exhibit a dominant negative phenotype.
Virology. 1990 Sep;178(1):327-30. Unique Identifier : AIDSLINE MED/90357785
Venkatesh LK; Chinnadurai G; Institute for Molecular Virology, St. Louis University School of; Medicine, Missouri 63110.
The rev protein (Rev) of human immunodeficiency virus increases the cytoplasmic expression of viral structural gene mRNAs. We had previously reported the existence of a region (residues 73-98) near the carboxy-terminus in HIV-1 Rev essential for its function. To further define the structural elements in this region, w


[A standard panel of human immunodeficiency virus-positive and negative blood sera for assessing the sensitivity and specificity of diagnostic immunoenzyme test systems]
Vopr Virusol. 1990 Mar-Apr;35(2):125-8. Unique Identifier : AIDSLINE MED/90357805
Vorob'eva MS; Shalamberidze TD; Fedorova GV; Suvorova ZK; Pokrovskii VV; Daulina MO; Liozner AL; Efremova EM
The materials on the development of a reference panel of HIV-positive and negative blood sera required for quality control of diagnostic enzyme-immunoassay systems are summarized. Ninety sera (50 HIV-antibody positive and 40 negative) were examined in 2 test systems of national and 3 test systems of foreign companies


[Stability of the main components of an EIA test system for the serodiagnosis of HIV infection]
Vopr Virusol. 1990 Mar-Apr;35(2):128-30. Unique Identifier : AIDSLINE MED/90357806
Marennikova SS; Shelukhina EM; Chekunova EV; Matsevich GR; Zaiko SD
The stability of two most important components of the EIA test system for diagnosis of HIV infection, an immunosorbent (HIV antigen adsorbed on polystyrene plates) and antispecies peroxidase conjugate, was studied. The possibility to prolong the shelf life of the test system for at least up to 6 months was demonstrate


Disseminated Pneumocystis carinii in a patient receiving aerosolized pentamidine prophylaxis.
West J Med. 1990 Jul;153(1):82-6. Unique Identifier : AIDSLINE MED/90357841
Berman SM; Shah B; Wyle FA; Dacosta-Iyer M; McRae DM; Medical Service, VA Medical Center, Long Beach, CA 90822.
Cumulative positivity rates of multiple blood cultures for Mycobacterium avium-intracellulare and Cryptococcus neoformans in patients with the acquired immunodeficiency syndrome.
Arch Pathol Lab Med. 1990 Sep;114(9):923-5. Unique Identifier : AIDSLINE MED/90358660
Yagupsky P; Menegus MA; Department of Clinical Microbiology, University of Rochester (NY); Medical Center.
We examined the occurrence of low-grade Mycobacterium avium-intracellulare bacteremia and Cryptococcus neoformans fungemia in patients with the acquired immunodeficiency syndrome and the consistency of positive cultures obtained using a sensitive blood culture system (Isolator, E. I. Du Pont de Nemours, Wilmington, De


Characterization of an internally initiated integrase protein of HIV-1 produced in E. coli.
Biochem Biophys Res Commun. 1990 Aug 16;170(3):1061-6. Unique Identifier : AIDSLINE MED/90358799
Zervos P; Hassell T; Van Frank R; Lai MT; Division of Molecular and Cell Biology Research, Lilly Research; Laboratories, Indianapolis, Indiana 46285.
In E. coli cells transformed by an expression vector for the production of the protease (PR) integrase (IN) of HIV-1, three vitally encoded proteins were produced: an 11-kDa protein and a 32-kDa protein identified by immunoassays as the mature PR and IN protein, respectively, and an additional protein 15-kDa in size t


Contraindications to immunisation [letter; comment]
S Afr Med J. 1990 Aug 4;78(3):169-70. Unique Identifier : AIDSLINE MED/90333353
If I have sex with a duck does that make me a drake? The Albion Street (AIDS) Centre, intravenous drug use and prostitution [letter; comment]
Med J Aust. 1990 May 7;152(9):498-9. Unique Identifier : AIDSLINE MED/90340172
Donovan B; Tindall B; Barnes T; Bodsworth N; Cunningham AL; Finlayson R; Price R; Robertson M; Wodak A; Ziegler JB; et al
HIV and granuloma inguinale in Durban [letter; comment]
S Afr Med J. 1990 Aug 18;78(4):220. Unique Identifier : AIDSLINE MED/90341884
O'Farrell N; Coetzee K
Attitudes, knowledge and behaviour of general practitioners in relation to HIV infection and AIDS. Commonwealth AIDS Research Grant Committee Working Party [see comments]
Med J Aust. 1990 Jul 2;153(1):5-12. Unique Identifier : AIDSLINE MED/90340198
A stratified random sample of 655 Australian general practitioners (GPs) was surveyed to determine their attitudes, knowledge and behaviour in relation to the human immunodeficiency virus (HIV) pandemic. Of the 486 respondents, 22% had one or more patients with HIV infection in their practice and 80% had been asked fo


[Bone banks in the FRG. Results of a survey (published erratum appears in Unfallchirurg 1990 Dec;93(12):583)]
Unfallchirurg. 1990 Jul;93(7):334-8. Unique Identifier : AIDSLINE MED/90341809
Jerosch J; Castro WH; Granrath M; Rosin H; Orthopadische Klinik, Universitat Dusseldorf.
In a nationwide survey, 1350 departments of general surgery, trauma surgery, and orthopedic surgery were approached in an attempt to determine how many surgeons use bone grafts and how they manage their bone banks; 961 responded to the postal enquiry. Bone banks are currently in use in 471 departments. The storage tem


The hippocratic irrelevance variable (HIV) [letter; comment] [see comments]
Med J Aust. 1990 May 7;152(9):499-500. Unique Identifier : AIDSLINE MED/90340173
The polymerase chain reaction in the diagnosis of vertically transmitted HIV infection.
AIDS. 1990 May;4(5):393-8. Unique Identifier : AIDSLINE MED/90321485
Williams P; Simmonds P; Yap PL; Balfe P; Bishop J; Brettle R; Hague R; Hargreaves D; Inglis J; Brown AL; et al; Blood Transfusion Centre, Royal Infirmary, Edinburgh, UK.
The presence of HIV-1 DNA sequences in DNA from peripheral blood mononuclear cells (PBMCs) was investigated in a two-stage polymerase chain reaction ( double PCR) using four sets of nested primers. The PBMCs tested were obtained from 46 children born to HIV-seropositive mothers, seven control children born to HIV-s


The effect in vitro of 2'-deoxycytidine on the metabolism and cytotoxicity of 2',3'-dideoxycytidine.
AIDS. 1990 May;4(5):427-31. Unique Identifier : AIDSLINE MED/90321490
Bhalla KN; Li GR; Grant S; Cole JT; MacLaughlin WW; Volsky DJ; Division of Hematology/Oncology, Medical University of South; Carolina, Charleston 29425.
We examined in vitro the effect of high, but clinically achievable and non-toxic, concentrations of 2 -deoxycytidine (dCyd) (greater than or equal to 100 mumols/l on the metabolism and cytotoxicity of 2 ,3 -dideoxycytidine (DDC) in normal human bone marrow mononuclear cells (BMMCs) and a cultured T-lymphocyte (HUT-102


Isolation and characterization of HIV-2ben obtained from a patient with predominantly neurological defects.
AIDS. 1990 May;4(5):455-7. Unique Identifier : AIDSLINE MED/90321494
Schneider J; Luke W; Kirchhoff F; Jung R; Jurkiewicz E; Stahl-Hennig C; Nick S; Klemm E; Jentsch KD; Hunsmann G; German Primate Center, Gottingen, FRG.
A HIV-2 strain named HIV-2ben was isolated from peripheral blood lymphocytes of a patient who, since 1984, had developed neurological symptoms such as Raynaud s syndrome, followed by paresthesia of extremities and ataxia, and finally paraparesis of the legs and incontinence. This new isolate could be distinguished fro


Lupus anticoagulant and HIV infection: a prospective study [letter]
AIDS. 1990 May;4(5):467-8. Unique Identifier : AIDSLINE MED/90321497
Boue F; Dreyfus M; Bridey F; Delfraissy JF; Dormont J; Tchernia G
HIV infection and AIDS in England and Wales: general practitioners' workload and contact with patients.
Br J Gen Pract. 1990 Apr;40(333):154-7. Unique Identifier : AIDSLINE MED/90321684
Gallagher M; Foy C; Rhodes T; Philips P; Setters J; Moore M; Naji S; Donaldson C; Bond J; Health Care Research Unit, University of Newcastle upon Tyne.
In mid-1988 a postal survey was conducted of one in five general practitioners in England and Wales, to examine their contact with people with human immunodeficiency virus (HIV) infection, with the acquired immune deficiency syndrome (AIDS) or with worries about HIV infection or AIDS. The response rate was 63.9%. Of t


Knowledge of HIV infection and AIDS, and attitudes to testing and counselling among general practitioners in Northern Ireland.
Br J Gen Pract. 1990 Apr;40(333):158-60. Unique Identifier : AIDSLINE MED/90321685
Boyd JS; Kerr S; Maw RD; Finnighan EA; Kilbane PK; Department of Genitourinary Medicine, Royal Victoria Hospital,; Belfast, Northern Ireland.
All 922 general practitioners in Northern Ireland were sent a questionnaire on human immunodeficiency virus (HIV) infection and the acquired immune deficiency syndrome (AIDS). Five hundred and ninety four general practitioners (64.4


Inhibition of lymphocyte IL2-receptor expression by factor VIII concentrate: a possible cause of immunosuppression in haemophiliacs.
Br J Haematol. 1990 Jun;75(2):278-81. Unique Identifier : AIDSLINE MED/90321870
Hay CR; McEvoy P; Duggan-Keen M; Department of Haematology, University of Liverpool.
Factor VIII concentrate inhibits T-cell function in vitro and in vivo. The mechanisms underlying the phenomenon were investigated. Factor VIII concentrate has a direct effect on lymphocytes, uninfluenced by haemophilic monocyte dysfunction, since it inhibited lymphocyte transformation with phorbol myristate acetate, a


Possible torsade in a patient with AIDS.
Hosp Pract (Off Ed). 1990 Jul 15;25(7):132-4. Unique Identifier : AIDSLINE MED/90324357
Hancock EW; Cardiology Division, Stanford University School of Medicine.
Prevention of HIV-1 infection and preservation of CD4 function by the binding of CPFs to gp120.
Science. 1990 Jul 20;249(4966):287-91. Unique Identifier : AIDSLINE MED/90327077
Finberg RW; Diamond DC; Mitchell DB; Rosenstein Y; Soman G; Norman TC; Schreiber SL; Burakoff SJ; Dana-Farber Cancer Institute, Department of Medicine, Harvard; Medical School, Boston, MA 02115.
Infection by human immunodeficiency virus type-1 (HIV-1) is initiated when its envelope protein, gp120, binds to its receptor, the cell surface glycoprotein CD4. Small molecules, termed N-carbomethoxycarbonyl-prolyl-phenylalanyl benzyl esters (CPFs), blocked this binding. CPFs interacted with gp120 and did not interfe


About leukocyte alkaline phosphatase in AIDS [letter; comment]
Acta Haematol. 1990;83(4):214. Unique Identifier : AIDSLINE MED/90327990
Grozdea J; Brisson-Lougarre A; Vergnes H; Alie-Daram S; Martin J; Bierme R
Cost-effectiveness of HIV screening of pregnant women in hospitals of the Paris area. The Paris-Tours study group of antenatal transmission of HIV, Group '9 maternites'.
Eur J Obstet Gynecol Reprod Biol. 1990 Oct;37(1):25-33. Unique Identifier : AIDSLINE MED/90330072
Le Gales C; Moatti JP; INSERM Unit 240 Evaluation of Risks and Effects of Prevention,; Fontenay-aux-Roses, France.
In the context of an epidemiologic multicentric study about perinatal transmission of HIV, screening was systematically proposed to all pregnant women attending nine maternities clinics of the Paris region (n = 7600, between August 1987 and July 1988) at their first prenatal visit. Among them, 2145 had already been te


[Tuberculosis and atypical mycobacterioses in HIV infection. Results from the Bonn Center 1985 to 1989]
Med Klin. 1990 Jun 15;85(6):355-60. Unique Identifier : AIDSLINE MED/90331879
Ewig S; Kuhnen E; Niese D; Musch E; von Kempis J; Medizinische Klinik, Universitat Bonn.
485 HIV-positive patients have been treated at our institution in Bonn during 1985 to 1989. Mycobacterial infections occurred in twelve (2.5%) HIV-positive patients. Of 166 AIDS-manifestations according to CDC, eleven (6.6%) were mycobacterial infections. There occurred one case of miliary tuberculosis, six cases of e


Reducing HIV transmission in intravenous-drug users not in drug treatment--United States.
MMWR Morb Mortal Wkly Rep. 1990 Aug 10;39(31):529, 535-8. Unique Identifier : AIDSLINE MED/90331906
Will chimps come up trumps in HIV war? [news]
Nursing (Lond). 1990 Jun 28-Jul 11;4(13):7. Unique Identifier : AIDSLINE MED/90332218
Gee CF
[AIDS prevention and care for mentally handicapped (news)]
TVZ. 1990 Jun 28;(13):432. Unique Identifier : AIDSLINE MED/90334739
Social and drug-taking behaviour of 'maintained' opiate addicts.
Br J Addict. 1990 Jun;85(6):771-4. Unique Identifier : AIDSLINE MED/90335464
Strang J; Johns A; Gossop M; Drug Dependence Clinical Research & Treatment Unit, Maudsley and; Bethlem Royal Hospitals, London, United Kingdom.
The roles of the prescribing of maintenance methadone and prescribing injectable drugs in the management of opiate addicts have become subjects of active debate since the advent of HIV. Data are presented on the social circumstances and drug-taking behaviour of 26 opiate addicts who had been receiving maintenance meth


Viral hepatitis and haemophilia.
Br Med Bull. 1990 Apr;46(2):408-22. Unique Identifier : AIDSLINE MED/90335644
Lee CA; Kernoff PB; Academic Department of Haematology, Royal Free Hospital, School; of Medicine, London.
Modern therapy with clotting factor concentrates has been dramatically successful in preventing and alleviating the worst effects of haemophilia. Before the mid to late 1980s, when effective methods of concentrate sterilization were introduced, such therapy was associated with a virtual certainty of transmission of vi


Modulation of the cell-mediated immune function by interferon alpha, beta or gamma can partially reverse the immunosuppression induced by human T-cell leukemia virus I in human cord blood cultures.
Cancer Immunol Immunother. 1990;31(4):213-20. Unique Identifier : AIDSLINE MED/90335896
D'Onofrio C; Pesce CD; Fontana T; Ciprani F; Bonmassar E; Calio R; Department of Experimental Medicine and Biochemical Sciences, II; University of Rome, Italy.
Infection with human T-cell leukemia virus type I (HTLV-I) is associated in vitro and in vivo with a remarkable depression of cell-mediated immune functions. In the present report it is shown that early events following virus-induced suppression of the cell-mediated immune response of freshly isolated cord blood monon


lck suppresses gene expression from various promoters including human T-cell leukemia virus type I promoter.
Jpn J Cancer Res. 1990 May;81(5):440-4. Unique Identifier : AIDSLINE MED/90337823
Ohta M; Morita T; Shimotohno K; Virology Division, National Cancer Center Research Institute,; Tokyo.
The T-lymphocyte-specific tyrosine kinase gene, lck, is expressed in T-lymphocyte cell lines, except for several human T-cell leukemia virus type I(HTLV-I)-transformed T-lymphocyte cell lines, which produce HTLV-I. By introducing an lck-expression vector, we found that lck product suppresses gene expression from HTLV-


Alga associated with diarrhea in patients with acquired immunodeficiency syndrome and in travelers.
J Clin Microbiol. 1990 Jun;28(6):1101-4. Unique Identifier : AIDSLINE MED/90338338
Long EG; Ebrahimzadeh A; White EH; Swisher B; Callaway CS; Division of Immunologic, Oncologic, and Hematologic Diseases,; Centers for Disease Control, Atlanta, Georgia 30333.
Spherical bodies resembling coccidian oocysts and measuring 8.0 to 9.0 microns in diameter were seen in the stools of eight persons with explosive, watery diarrhea. Seven had recently traveled to tropical countries, mostly in the Caribbean, and four had acquired immunodeficiency syndrome. The structures were easily di


Anti-idiotypic antibodies of a predefined specificity generated against CDR3VH synthetic peptides define a private anti-CD4 idiotype.
Mol Immunol. 1990 Jun;27(6):513-22. Unique Identifier : AIDSLINE MED/90340318
Attanasio R; Kennedy RC; Allan JS; Maino VC; Buck D; Kanda P; Department of Virology and Immunology, Southwest Foundation for; Biomedical Research, San Antonio, TX 78284.
A synthetic peptide corresponding to the third complementarity determining region (CDR) of the heavy chain (CDR3VH) of anti-Leu3a, a monoclonal anti-CD4 antibody which inhibits HIV gp120 binding to CD4, was used to elicit specific anti-peptide antibodies in rabbits. The anti-peptide antisera showed anti-idiotypic anti


Underreporting of minority AIDS deaths in San Francisco Bay area, 1985-86.
Public Health Rep. 1990 Jul-Aug;105(4):400-4. Unique Identifier : AIDSLINE MED/90341481
Lindan CP; Hearst N; Singleton JA; Trachtenberg AI; Riordan NM; Tokagawa DA; Chu GS; Center for AIDS Prevention Studies (CAPS), University of; California, San Francisco.
A disproportionately high number of AIDS cases in the United States involve members of racial minorities. Even so, AIDS deaths of minority members may be undercounted. The completeness of reporting of AIDS deaths to the California AIDS Registry (ARS) among Hispanics, blacks, and whites


Imipenem resistance in a case of AIDS with relapsing Pseudomonas meningitis.
South Med J. 1990 Aug;83(8):979-80. Unique Identifier : AIDSLINE MED/90341849
Eng RH; Lynch AM; Smith SM; Ambros RA; Fan-Havard P; Mangia A; Tecson-Tumang F; Cherubin C; Veterans Administration Medical Center, Orange, NJ 07019.
We describe an AIDS patient who had a recurrence of Pseudomonas meningitis to illustrate three points. First, the use of sulfamethoxazole-trimethoprim in AIDS patients for prophylaxis of Pneumocystis carinii pneumonia may cause the various body sites to be colonized with resistant species such as P aeruginosa. Second,


[Type C viral hepatitis]
Rev Fr Transfus Hemobiol. 1990 Mar;33(2):81-95. Unique Identifier : AIDSLINE MED/90343925
Courouce AM
Promising results for new AIDS/ARC drug [news]
Nurs Stand. 1990 Jun 13-19;4(38):16. Unique Identifier : AIDSLINE MED/90344612
Caring for Romania appeal: against all the odds.
Nurs Stand. 1990 Jun 13-19;4(38):17-9. Unique Identifier : AIDSLINE MED/90344613
Casey N
Pharyngeal ulceration of AIDS treatable [news]
Nurs Stand. 1990 Jun 20-26;4(39):16. Unique Identifier : AIDSLINE MED/90344626
Bearing witness.
Nurs Stand. 1990 Jun 27-Jul 3;4(40):43. Unique Identifier : AIDSLINE MED/90344651
Atkinson J
AIDS and HIV infection. Nurses show basic 'lack of knowledge' [news]
Nurs Stand. 1990 Aug 1-7;4(45):5. Unique Identifier : AIDSLINE MED/90344683
Alternating zinc-finger motifs in the human male-associated protein ZFY.
Biochemistry. 1990 Jun 19;29(24):5660-4. Unique Identifier : AIDSLINE MED/90344784
Weiss MA; Mason KA; Dahl CE; Keutmann HT; Department of Biological Chemistry and Molecular Pharmacology,; Harvard Medical School, Boston, Massachusetts 02115.
ZFY, a putative transcription factor encoded by the human Y chromosome, contains a distinctive two-finger repeat: odd-numbered and even-numbered CC/HH metal-binding motifs exhibit systematic alternation in sequence pattern. Such alternation, which is not generally observed in zinc-finger proteins, has also been descri


Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.
Genes Dev. 1990 Jun;4(6):1014-22. Unique Identifier : AIDSLINE MED/90346282
Ahmed YF; Hanly SM; Malim MH; Cullen BR; Greene WC; Howard Hughes Medical Institute, Department of Medicine, Duke; University Medical Center, Durham, North Carolina 27710.
The ability of the Rex protein of the type I human T-cell leukemia virus (HTLV-I) to regulate expression of the retroviral gag and env structural genes post-transcriptionally is critically dependent on the presence of a Rex response element (RexRE). This cis-regulatory sequence is located within the retroviral 3 long


Effects of disinfectants on dimensional accuracy of impression materials.
J Prosthet Dent. 1990 Jul;64(1):25-31. Unique Identifier : AIDSLINE MED/90347767
Matyas J; Dao N; Caputo AA; Lucatorto FM; Biomaterials Science Section, University of California, School of; Dentistry, Los Angeles.
There is a continuing concern over the potential for cross-contamination of viral infections such as AIDS by means of dental impressions. This investigation compared the effects of various viricidal agents on the accuracy of irreversible hydrocolloid and silicone impressions made of single-unit and full mandibular arc


Persistent infection of rhesus macaques with a molecular clone of human immunodeficiency virus type 2: evidence of minimal genetic drift and low pathogenetic effects.
J Virol. 1990 Sep;64(9):4462-7. Unique Identifier : AIDSLINE MED/90347844
Franchini G; Markham P; Gard E; Fargnoli K; Keubaruwa S; Jagodzinski L; Robert-Guroff M; Lusso P; Ford G; Wong-Staal F; et al; Laboratory of Tumor Cell Biology, National Cancer Institute,; Bethesda, Maryland 20892.
In an attempt to generate a suitable animal model to study the infectivity and possible pathogenicity of human immunodeficiency viruses, we intravenously inoculated juvenile rhesus macaques and African green monkeys with a molecularly cloned virus, human immunodeficiency virus type 2 HIV-2sbl/isy, as well as with the


From the National Institutes of Health.
JAMA. 1990 Sep 5;264(9):1086. Unique Identifier : AIDSLINE MED/90347870
Raub W; National Institutes of Health, Bethesda, MD 20892.
Aerosol therapy in AIDS.
Lung. 1990;168 Suppl:685-91. Unique Identifier : AIDSLINE MED/90348359
Newman SP; Simonds AK; Department of Thoracic Medicine, Royal Free Hospital, London,; United Kingdom.
Pneumocystis carinii pneumonia (PCP) is the most common presenting symptom in patients with the acquired immunodeficiency syndrome (AIDS). Clinical trials have shown that inhaled pentamidine, delivered by nebulizer, is an effective prophylaxis for PCP in high-risk patients, and can be used to treat mild to moderate ep


Drug resistant tuberculosis among the homeless in New York City.
N Y State J Med. 1990 Jul;90(7):351-5. Unique Identifier : AIDSLINE MED/90349145
Pablos-Mendez A; Raviglione MC; Battan R; Ramos-Zuniga R; Department of Medicine, Cabrini Medical Center, New York, NY; 10003.
The purpose of this study was to compare the frequency of infections due to drug resistant Mycobacterium tuberculosis between homeless and nonhomeless populations in an urban community hospital. We retrospectively examined the mycobacteriology registry of this hospital for culture-proven, susceptibility-tested cases o


Advances in the management of HIV disease: focus on didanosine (ddI). A symposium. Houston, Texas, 18 September 1989. Proceedings.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S499-576. Unique Identifier : AIDSLINE MED/90349969
Overview of the preclinical development of an antiretroviral drug, 2',3'-dideoxyinosine.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S513-20; discussion S520-1. Unique Identifier : AIDSLINE MED/90349972
McGowan JJ; Tomaszewski JE; Cradock J; Hoth D; Grieshaber CK; Broder S; Mitsuya H; AIDS Program, National Institute of Allergy and Infectious; Diseases, National Institutes of Health, Bethesda, Maryland; 20892.
AIDS has remained a significant and worsening medical problem since its first description as a new clinical entity in 1981. In the past 6 years, substantial progress has been made in the chemotherapy for this disease; such progress is likely to exert a major effect on the epidemic of human immunodeficiency virus infec


Aspergillus endocarditis and myocarditis in a patient with the acquired immunodeficiency syndrome (AIDS). A review of the literature.
Virchows Arch A Pathol Anat Histopathol. 1990;417(3):255-9. Unique Identifier : AIDSLINE MED/90350268
Cox JN; di Dio F; Pizzolato GP; Lerch R; Pochon N; Department of Pathology, University of Geneva, Switzerland.
We report the post-mortem findings of the case of a 31-year-old male who, through sexual contacts with a female drug addict, was found to be HIV-positive and developed the acquired immunodeficiency syndrome (AIDS) 2 years later. He was treated for various opportunistic infections over the next 7 years when he presente


HIV-1 infection and virus production in follicular dendritic cells in lymph nodes. A case report, with analysis of isolated follicular dendritic cells.
Am J Pathol. 1990 Aug;137(2):247-51. Unique Identifier : AIDSLINE MED/90350792
Parmentier HK; van Wichen D; Sie-Go DM; Goudsmit J; Borleffs JC; Schuurman HJ; Department of Internal Medicine, University Hospital, Utrecht,; The Netherlands.
Follicular dendritic cells (FDC) from axillary lymphoid tissue of a patient with acquired immune deficiency syndrome (AIDS) were analyzed for the presence of gag and env proteins and env mRNA of human immunodeficiency virus type-1 (HIV-1), both in a purified FDC suspension and on frozen sections. Isolated cells with m


HLA class I soluble antigen serum levels in HIV-positive subjects--correlation with cellular and serological parameters.
Cancer Detect Prev. 1990;14(3):321-3. Unique Identifier : AIDSLINE MED/90352632
Puppo F; Orlandini A; Ruzzenenti R; Comuzio S; Salamito A; Farinelli A; Stagnaro R; Indiveri F
HLA Class I soluble antigen serum levels have been evaluated in 178 subjects who were positive for human immunodeficiency virus (HIV) and in 66 HIV-negative controls. The serum levels of HIV p24 antigen, interleukin 2 receptor (IL 2r), CD8 soluble antigen (CD 8ag), B2-microglobulin (B2-m), and neopterin (Npt), as well


Inactivation of HIV-1 and HIV-2 by various manufacturing procedures for human plasma proteins.
Cancer Detect Prev. 1990;14(3):369-75. Unique Identifier : AIDSLINE MED/90352641
Hilfenhaus JW; Gregersen JP; Mehdi S; Volk R
Human retroviruses causing AIDS (HIV-1, HIV-2) can occur in human plasma donations. Since HIV-contaminated plasma cannot be completely excluded by testing for anti-HIV-1 (routine plasma screening for anti-HIV-2 has not yet been established), a safeguard against AIDS in therapeutics derived from human plasma can only b


Multiple myeloma in a patient at risk for AIDS.
Cancer Detect Prev. 1990;14(3):403-4. Unique Identifier : AIDSLINE MED/90352646
von Keyserlingk H; Baur R; Stein H; Hoeffken G; Thiel E; FU Klinikum Steglitz, Abteilung fur Innere Medizin mit, Berlin,; Federal Republic of Germany.
An increased incidence of tumors and B-cell lymphomas development has been reported in persons with or at risk for acquired immunodeficiency syndrome (AIDS). This report focuses on a 50-year-old homosexual man with HIV antibodies who met the established criteria for the diagnosis of multiple myeloma: an IgG monoclonal


Prospects for an AIDS vaccine.
Cancer Detect Prev. 1990;14(3):411-3. Unique Identifier : AIDSLINE MED/90352648
Girard M; Pasteur Vaccins, Marnes La Coquette, France.
The development of a vaccine against HIV meets with considerable difficulties. The virus shows considerable genetic variability. Neutralizing antibodies raised against one HIV-1 isolate do not cross-neutralize other HIV-1 isolates. HIV can also spread directly from cell to cell without entering extracellular fluids, t


Trans-activation by HIV-1 Tat via a heterologous RNA binding protein.
Cell. 1990 Aug 24;62(4):769-76. Unique Identifier : AIDSLINE MED/90352710
Selby MJ; Peterlin BM; Howard Hughes Medical Institute, University of California, San; Francisco 94143-0724.
The HIV-1 trans-activator Tat increases levels of viral gene expression and replication. The target for Tat is an RNA stem-loop called TAR, located at the 5 end of all viral transcripts. To study the mechanism of action and map functional domains of Tat, we fused Tat to the coat protein of bacteriophage MS2, an RNA b


A phase 1 study of ribavirin in human immunodeficiency virus-infected patients.
J Infect Dis. 1990 Sep;162(3):638-42. Unique Identifier : AIDSLINE MED/90354702
Roberts RB; Jurica K; Meyer WA 3d; Paxton H; Makuch RW; New York Hospital-Cornell Medical Center, New York City.
An open phase 1 study comparing two daily doses of oral ribavirin (1200 and 1600 mg) for 12 weeks was conducted at a single site. Eight human immunodeficiency virus (HIV)-infected adult men with lymphadenopathy or early AIDS-related complex (ARC) symptoms were enrolled in each treatment group. No anti-HIV effect was o


Lack of effect of lithium carbonate on zidovudine-associated neutropenia in patients with AIDS [letter]
J Infect Dis. 1990 Sep;162(3):777-8. Unique Identifier : AIDSLINE MED/90354730
Worthington M
Co-infection of macrophages modulates interferon gamma and tumor necrosis factor-induced activation against intracellular pathogens.
J Exp Med. 1990 Sep 1;172(3):977-80. Unique Identifier : AIDSLINE MED/90354801
Black CM; Bermudez LE; Young LS; Remington JS; Department of Immunology and Infectious Diseases, Palo Alto; Medical Foundation, California 94301.
Co-infection of macrophages (M phi) with Toxoplasma gondii and Mycobacterium avium-intracellulare complex (MAC) has been observed in patients with acquired immunodeficiency syndrome (AIDS). In this study we have demonstrated that co-infected murine M phi respond differently to cytokine stimulation than M phi infected


Cultivation of human immunodeficiency virus from whole blood: effect of anticoagulant and inoculum size on virus growth.
J Med Virol. 1990 Jun;31(2):161-4. Unique Identifier : AIDSLINE MED/90354817
Bayliss GJ; Jesson WJ; Mortimer PP; McLean KA; Evans BA; Virus Reference Laboratory, Central Public Health Laboratory,; London, England.
Human immunodeficiency virus (HIV) was cultivated directly from whole blood treated with anticoagulant by cocultivation with phytohaemagglutinin-stimulated cord blood lymphocytes. When heparin was used as the anticoagulant, isolation rates were low (10% to 56%, depending on the patient group); but when EDTA was used,


Advantages and disadvantages of special hospitals for patients with HIV infection. A report by the New York City Task Force on Single-Disease Hospitals [see comments]
N Engl J Med. 1990 Sep 13;323(11):764-8. Unique Identifier : AIDSLINE MED/90356096
Rothman DJ; Tynan EA; College of Physicians and Surgeons of Columbia University, New; York, NY 10032.
Antiviral and antiproliferative activities of recombinant human interferon alpha 2, beta and gamma on HTLV-I and ATL cells in vitro.
Sangyo Ika Daigaku Zasshi. 1990 Jun 1;12(2):149-61. Unique Identifier : AIDSLINE MED/90356901
Koyama Y; Tanaka Y; Oda S; Yamashita U; Eto S; First Department of Internal Medicine, School of Medicine,; University of Occupational and Environmental Health, Kitakyushu,; Japan.
ATL (Adult T cell leukemia) causes severe immune deficiency. Furthermore, aggravation of immune deficiency is a major problem in chemotherapy of ATL. In expectation of antiviral, antineoplastic and increasing immunological activity, several clinical trials of Interferons (IFNs) on ATL have been reported. However, as t


Enterocytozoon bieneusi (Microspora): prevalence and pathogenicity in AIDS patients.
Trans R Soc Trop Med Hyg. 1990 Mar-Apr;84(2):181-6. Unique Identifier : AIDSLINE MED/90357342
Canning EU; Hollister WS; Department of Pure and Applied Biology, Imperial College of; Science, Technology and Medicine, London, UK.
Microsporidia are unicellular organisms, which lack mitochondria. They have prokaryotic-like ribosomes and characteristic spores containing an extrusible polar tube which serves as a passage for inoculation of the infectious agent (sporoplasm) into host cells. Clinically apparent infections in man appear to be limited


Synthesis, oligomerization, and biological activity of the human immunodeficiency virus type 2 envelope glycoprotein expressed by a recombinant vaccinia virus.
Virology. 1990 Sep;178(1):134-42. Unique Identifier : AIDSLINE MED/90357756
Chakrabarti S; Mizukami T; Franchini G; Moss B; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, Bethesda, MD 20892.
The full-length envelope gene from an infectious human immunodeficiency virus type 2 (HIV-2) molecular clone was expressed in CD4+ and CD4- cells by a recombinant vaccinia virus vector. Pulse-chase experiments indicated that gp160 was processed into gp120 and gp41 subunits. Although large amounts of gp120 were shed in


[Dynamics of the antibody response and p24 antigenemia in HIV-1 infected individuals in Czechoslovakia]
Cesk Epidemiol Mikrobiol Imunol. 1990 Mar;39(2):65-73. Unique Identifier : AIDSLINE MED/90322451
Kopecka D; Bruckova M; Stankova M; Syrucek L; Vojtechovsky K; Petkov V; Institut hygieny a epidemiologie, Praha.
In a group of 83 anti HIV-1 positive subjects the antibody response against different structural viral proteins was investigated concurrently with assessment of p 24 antigenaemia. Disappearance of antibodies against the capsidal antigen p 24 was recorded in 12% of 42 patients with ARC and AIDS. On the other hand, thes


[Detection of HIV infection using the immunofluorescence test]
Cesk Epidemiol Mikrobiol Imunol. 1990 Mar;39(2):74-7. Unique Identifier : AIDSLINE MED/90322452
Vojtechovsky K; Bruckova M; Kopecka D; Syrucek L; Petkov V; Institut hygieny a epidemiologie, Praha.
The author examined, using the immunofluorescence test, 107 ant HIV positive sera and 114 sera with false reactions in the ELISA test. He proved a high sensitivity and specificity of the immunofluorescence test in the detection of anti-HIV antibodies, comparable with Western-blot s technique and he established the val


[Preventive pentamidine inhalation in patients with HIV infection (CD3 and CD4) in ambulatory practice]
Med Klin. 1990 Apr;85 Suppl 2:286-7, 291. Unique Identifier : AIDSLINE MED/90326043
Baranowski E
Over a time-period of twelve months in a one-center drug monitoring trial a) the efficacy of pentamidine-aerosol for the prophylaxis of pneumocystis carinii pneumonia and b) the patient compliance was investigated. The results of 73 patients who have been treated since the fourth quarter 1988, were evaluated. None of


Photodynamic therapy for treatment of AIDS-related oral Kaposi's sarcoma.
Otolaryngol Head Neck Surg. 1990 Jun;102(6):639-49. Unique Identifier : AIDSLINE MED/90326425
Schweitzer VG; Visscher D; Department of Otolaryngology-Head and Neck Surgery, Henry Ford; Hospital, Detroit, MI 48202.
Since 1975, Phase I and II studies have demonstrated the successfulness of hematoporphyrin derivative photodynamic therapy in the treatment of various malignancies of the skin, eye, bladder, lung, and head and neck. Moreover, two cases of traditional Western cutaneous Kaposi s sarcoma (TKS) have been treated with phot


[Value of anticardiolipin antibody assay in human immunodeficiency virus infection]
Presse Med. 1990 Jun 30;19(26):1225-7. Unique Identifier : AIDSLINE MED/90326656
Lafeuillade A; Delbeke E; Chaffanjon P; Aubert L; Dhiver C; Gastaut JA; Quilichini R; Service de Medecine interne et Hematologie, Hopital Chalucet,; Toulon.
Recently published encouraging data concerning the value of anticardiolipin antibody assays in patients with HIV infection, both for prognostic purposes and to diagnose pneumocystosis, have prompted us to evaluate these assays in a series of 116 patients. We were unable to demonstrate any correlation between the level


Arkansas physician in national spotlight regarding AIDS epidemic.
J Ark Med Soc. 1990 Jul;87(2):92-3. Unique Identifier : AIDSLINE MED/90330484
Physicians with AIDS.
J Ark Med Soc. 1990 Jul;87(2):94. Unique Identifier : AIDSLINE MED/90330485
Uzych L
[The detection of human cryptosporidiosis in Leningrad]
Med Parazitol (Mosk). 1990 Mar-Apr;(2):45-8. Unique Identifier : AIDSLINE MED/90331869
Beier TV; Antykova LP; Gerbina GI; Sargaeva VG; Sidorenko NV
Stool specimens from 127 adults with gastrointestinal disorders, 357 persons engaged in a livestock farming in the district of Leningrad were examined for Cryptosporidium oocysts with the Ziehl-Neelson routine. Five positive cases were established among the latter cohort. Besides, the study conducted at the hospitals


Cutaneous response to recombinant interleukin 2 in human immunodeficiency virus 1-seropositive individuals.
Proc Natl Acad Sci U S A. 1990 Aug;87(15):5783-7. Unique Identifier : AIDSLINE MED/90332666
McElrath MJ; Kaplan G; Burkhardt RA; Cohn ZA; Laboratory of Cellular Physiology and Immunology, Rockefeller; University, New York, NY 10021.
We report that 11 human immunodeficiency virus 1 (HIV-1)-seropositive patients, including three AIDS patients, were able to generate a cellular immune response to the intradermal injection of low doses (2-10 micrograms) of recombinant interleukin 2 (rIL-2). A dose-dependent zone of induration appeared at the site of i


Zidovudine for asymptomatic HIV-infected patients: answers and questions.
J Am Board Fam Pract. 1990 Jul-Sep;3(3):221-3. Unique Identifier : AIDSLINE MED/90333963
Goldschmidt RH; Family Practice Inpatient Service, San Francisco General; Hospital, CA 94110.
[Risk factors for infection among the patrons of an HIV Control Program, Antioquia, Colombia]
Bol Oficina Sanit Panam. 1990 Mar;108(3):181-97. Unique Identifier : AIDSLINE MED/90334718
Gomez RD; Arango MV; Velazquez G; Orozco B; Servicio Seccional de Salud, Laboratorio Departamental de Salud; Publica, Antioquia, Colombia.
A review is presented of the characteristics of 432 users of the Human Immunodeficiency Virus (HIV) Control Program sponsored by the Public Health Departmental Laboratory of Antioquia, Colombia , who were seen between July 1988 and J


Leukocyte function-associated antigen-1 expression on peripheral blood mononuclear cell subsets in HIV-1 seropositive patients.
Clin Immunol Immunopathol. 1990 Aug;56(2):159-68. Unique Identifier : AIDSLINE MED/90336144
Vermot Desroches C; Rigal D; Laboratoire d'Immunologie, Centre Regional de Tranfusion; Sanguine, Lyon, France.
In order to further investigate immune dysfunctions in HIV-1 infection, we studied the intensity of leukocyte function-associated antigen-1 (LFA-1) expression using a novel application of immunofluorescence analysis in 14 adults and 5 children seropositive for HIV-1 and in 14 healthy adults and 5 healthy children sero


Human immunodeficiency virus infection of monocytes: relationship to Fc-gamma receptors and antibody-dependent viral enhancement.
Immunology. 1990 Jul;70(3):338-43. Unique Identifier : AIDSLINE MED/90337548
Laurence J; Saunders A; Early E; Salmon JE; Division of Hematology-Oncology, New York Hospital-Cornell; Medical Center, New York.
Antibodies that augment human immunodeficiency virus (HIV) infectivity of monocytes through Fc receptor (FcR) type III for IgG have been found in the blood of sero-positive patients and immunized chimpanzees. This study investigated the effect of acute and chronic HIV infection, as well as protein kinase C activators


Rationale for anti-AIDS chemotherapy directed at HIV-1 infected dendritic cells in seropositive individuals prior to the appearance of ARC and AIDS.
J Chemother. 1990 Jun;2(3):152-5. Unique Identifier : AIDSLINE MED/90339111
Becker Y; Department of Molecular Virology, Faculty of Medicine, Hebrew; University, Jerusalem, Israel.
An approach to anti-AIDS chemotherapy is presented from the point of view of treating seropositive individuals by eliminating the infected dendritic cells that are the in vivo target of HIV-1. Special attention is given to the treatment of Langerhans (dendritic) cells in the skin and epithelia that are infected in viv


Compassion, compensation and HIV [editorial]
Med J Aust. 1990 Jul 2;153(1):1-2. Unique Identifier : AIDSLINE MED/90340186
Dwyer JM
[Psychosocial factors of participation in HIV testing]
Offentl Gesundheitswes. 1990 Jul;52(7):316-22. Unique Identifier : AIDSLINE MED/90340696
Doll J; Juhl K; Psychologisches Institut I, Universitat Hamburg.
The relevance of the attitude toward the HIV test, the subjectively perceived infection risk, the expected consequences of testing, and the perceived reference group influences for HIV antibody testing is studied. 211 persons, who were tested for AIDS in an AIDS consulting institution, and 86 controls, who had not bee


[Changes in sex behavior caused by fear of AIDS--an empirical study of male heterosexual and homosexual students]
Offentl Gesundheitswes. 1990 Jul;52(7):323-9. Unique Identifier : AIDSLINE MED/90340697
Tillmann K; Braun R; Clement U; Berliner AIDS-Hilfe e.V.
This study examines changes in sexual behaviour in the context of the fear of being infected with the HI-Virus and, in particular, considers the influence of a relationship and of sexual orientation. The population studied included 72 homosexual and 54 heterosexual male students. Results: (1) Only 7% of the heterosexu


[AIDS problems in sex education in the schools of the Republic of Bavaria]
Offentl Gesundheitswes. 1990 Jul;52(7):330-3. Unique Identifier : AIDSLINE MED/90340698
Dietz LJ
To prevent the risk of infection, learn to speak about and accept safer sex and the use of condoms as early as possible. Take care of your partner and yourself. Most of the teachers are not prepared to teach boys and girls in a qualified way. Teach and learn to fight fear with facts: Say No to fear! Don t give infecti


[Street work and AIDS--experiences and considerations from a socio-pedagogic viewpoint]
Offentl Gesundheitswes. 1990 Jul;52(7):334-7. Unique Identifier : AIDSLINE MED/90340699
Riegel E; Gesundheitsamt der Stadt Augsburg.
Streetwork has proved its worth as a method that is useful in AIDS work. The emphasis is on rendering direct help to the affected persons. This help has indirectly a preventive effects as well because it initiates and supports action that is directly related to social care. Self-initiatives of patients with a positive


Messenger RNA transport and HIV rev regulation.
Science. 1990 Aug 10;249(4969):614-5. Unique Identifier : AIDSLINE MED/90341784
Chang DD; Sharp PA; Department of Biology, Massachusetts Institute of Technology,; Cambridge 02139.
Hospice: enhancing the quality of life.
Oncology (Huntingt). 1990 May;4(5):121-6; discussion 129. Unique Identifier : AIDSLINE MED/90344513
Lamers WM Jr; Bresler Center, Santa Monica, California.
Hospice care is directed at the relief of the physical, social and psychologic symptoms that often accompany advanced, incurable illness. In recent years, an increasing number of physicians has come to recognize the necessity for hospice care in the treatment of some patients with cancer, HIV infection, and a number o


Induction of sensitivity to the cytotoxic action of tumor necrosis factor alpha by adenovirus E1A is independent of transformation and transcriptional activation.
J Virol. 1990 Sep;64(9):4115-22. Unique Identifier : AIDSLINE MED/90347802
Ames RS; Holskin B; Mitcho M; Shalloway D; Chen MJ; Department of Molecular Genetics, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania 19406-0939.
We have previously shown that expression of the adenovirus E1A 12S or 13S products in NIH 3T3 fibroblasts induces susceptibility to the cytotoxic actions of tumor necrosis factor alpha (TNF alpha). A large number of studies have mapped the multiple biological functions of the 12S and 13S products to three highly conse


[An intrahospital outbreak of HIV infection in Elista]
Zh Mikrobiol Epidemiol Immunobiol. 1990 Apr;(4):17-23. Unique Identifier : AIDSLINE MED/90350369
Pokrovskii VV; Eramova IIu; Deulina MO; Lipetikov VV; Iashkulov KB; Sliusareva LA; Chemizova NM; Savchenko SP
For the first time a nosocomial focus of HIV infection was established. Out of 83,000 inhabitants of the Kalmyck ASSR who underwent planned examination in the course of epidemiological investigation, 65 cases of HIV infection were detected and all of them were traced to the focus of hospital infection (56 children and


[The organization of an epidemiological surveillance of HIV infection in Krasnodar Territory]
Zh Mikrobiol Epidemiol Immunobiol. 1990 Apr;(4):23-6. Unique Identifier : AIDSLINE MED/90350370
Kalashnikov IA; Beliaev EN; Pokrovskii VV; Dolgov VN; Mkrtvchan MO; Kovalenko IuG; Iarov TV; Balanov NI; Brudnyi RA; Leshchenko MV; et al
For the first time a case of AIDS was detected in the Krasnodar Territory of the USSR, and the presence of HIV infection in homosexuals, foreign students, and promiscuous persons was established. To study the spread of HIV infection, 5 diagnostic laboratories were created and 5 routes for the transportation of sera we


[Ethics and dentistry]
Actual Odontostomatol (Paris). 1990 Mar;44(169):185-94. Unique Identifier : AIDSLINE MED/90350567
Muller M; Francoual H
Is Odontology asserved to ethical? Three thought s axis are considered: 1. Ethical and research. 2. Negligence during cares. 3. Refusal to give cares (AIDS).


Clinical trial to test whether BMT and AZT can eliminate AIDS virus [news]
Oncology (Huntingt). 1990 Feb;4(2):91. Unique Identifier : AIDSLINE MED/90352063
FDA approves AZT for pediatric AIDS patients under 13 [news]
Oncology (Huntingt). 1990 Feb;4(2):96. Unique Identifier : AIDSLINE MED/90352067
Decreased serum levels of IgE and IgE-binding factors in individuals infected with HTLV-I.
Clin Exp Immunol. 1990 Aug;81(2):207-11. Unique Identifier : AIDSLINE MED/90352856
Matsumoto T; Miike T; Mizoguchi K; Yamaguchi K; Takatsuki K; Hosoda M; Kawabe T; Yodoi J; Department of Child Development, Kumamoto University Medical; School, Japan.
The cell surface expression of low-affinity Fc epsilon receptor (Fc epsilon RII), which is identical to CD23, and the serum levels of IgE binding factors (IgE BFs), a soluble form of Fc epsilon RII, and IgE were investigated in HTLV-I-infected individuals, and the results were compared with those for HTLV-I-negative c


Diminished response to recombinant hepatitis B vaccine in homosexual men with HIV antibody: an indicator of poor prognosis.
J Med Virol. 1990 Jun;31(2):109-11. Unique Identifier : AIDSLINE MED/90354809
Loke RH; Murray-Lyon IM; Coleman JC; Evans BA; Zuckerman AJ; Department of Gastroenterology, Charing Cross Hospital, London,; England.
Three doses of a recombinant DNA HBV vaccine (MSD) were given to healthy male homosexuals. Seventy-eight out of 104 (77.6%) participants had detectable antibody (anti-HBs) two months after the third dose. Seroconversion occurred in only 9 out of 27 subjects (33.3%) who were anti-HIV positive compared with 69 out of 77


Waiter with AIDS wins job-bias suit [news]
Occup Health Saf. 1990 Jul;59(7):9. Unique Identifier : AIDSLINE MED/90356218
[Cavitary Pneumocystis carinii pneumonia in AIDS (letter)]
Presse Med. 1990 Jul 7-14;19(27):1283-4. Unique Identifier : AIDSLINE MED/90356510
Dell'Isola B; Janssen F; Sarfati C; Modai J
Requirements for simian immunodeficiency virus antigen-specific in vitro proliferation of T cells from infected rhesus macaques and sooty mangabeys.
AIDS. 1990 May;4(5):399-407. Unique Identifier : AIDSLINE MED/90321486
Ahmed-Ansari A; Powell JD; Jensen PE; Yehuda-Cohen T; McClure HM; Anderson D; Fultz PN; Sell KW; Department of Pathology and Laboratory Medicine, Winship Cancer; Center, Emory University School of Medicine, Atlanta, Georgia; 30322.
The measurement of cell-mediated immunity against the etiologic agent of human AIDS (HIV) in the non-human primate model of AIDS (simian immunodeficiency virus, SIV) has been difficult. In general, culture of peripheral blood mononuclear cells from HIV-1- and SIV-infected humans and monkeys, respectively, with purifie


Therapy for cytomegalovirus polyradiculomyelitis in patients with AIDS: treatment with ganciclovir.
AIDS. 1990 May;4(5):421-5. Unique Identifier : AIDSLINE MED/90321489
de Gans J; Portegies P; Tiessens G; Troost D; Danner SA; Lange JM; Department of Neurology, Academisch Medisch Centrum, Amsterdam,; The Netherlands.
Six AIDS patients with progressive cytomegalovirus ( CMV ) polyradiculomyelitis were treated with ganciclovir in an open study. The diagnosis was based on the presence of a distinct clinical syndrome with progressive flaccid pa


Dose-limiting toxicity of rifabutin in AIDS-related complex: syndrome of arthralgia/arthritis.
AIDS. 1990 May;4(5):433-41. Unique Identifier : AIDSLINE MED/90321491
Siegal FP; Eilbott D; Burger H; Gehan K; Davidson B; Kaell AT; Weiser B; Department of Medicine, Long Island Jewish Medical Center, New; Hyde Park 11042.
We studied the tolerance of humans to rifabutin, a rifamycin with antimycobacterial and in vitro anti-HIV activity. Sixteen subjects with AIDS-related complex were treated for 4-66 weeks with stepwise increasing oral doses of rifabutin from 300 to 2400 mg/day. The highest dose attained was twice that previously report


A comparison of HIV-1 and HIV-2 infections in hospitalized patients in Abidjan, Cote d'Ivoire.
AIDS. 1990 May;4(5):443-8. Unique Identifier : AIDSLINE MED/90321492
De Cock KM; Odehouri K; Colebunders RL; Adjorlolo G; Lafontaine MF; Porter A; Gnaore E; Diaby L; Moreau J; Heyward WL; et al; Projet RETRO-CI, Abidjan, Cote d'Ivoire.
In late 1988, a cross-sectional study of 1715 adult medical patients hospitalized in Abidjan, Cote d Ivoire , west Africa, showed an overall prevalence of HIV infection of 46% in men and 28% in women. On the basis of specific testing by whole virus enzyme-linked immunosorbent a


[Venereal diseases: tests influenced by HIV. Herpes genitalis--HPV-syphilis]
Fortschr Med. 1990 May 10;108(14):26, 28. Unique Identifier : AIDSLINE MED/90323743
Moosmann EB
Molecular interactions among herpesviruses and human immunodeficiency viruses.
J Infect Dis. 1990 Aug;162(2):338-46. Unique Identifier : AIDSLINE MED/90324643
Laurence J; Laboratory for AIDS Virus Research, Cornell University Medical; College, New York City, NY 10021.
Synthesis and antiviral activity of monofluoro and difluoro analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1).
J Med Chem. 1990 Aug;33(8):2137-45. Unique Identifier : AIDSLINE MED/90325204
Martin JA; Bushnell DJ; Duncan IB; Dunsdon SJ; Hall MJ; Machin PJ; Merrett JH; Parkes KE; Roberts NA; Thomas GJ; et al; Research Division, Roche Products Limited, Welwyn Garden City,; Hertfordshire, England.
A range of 2 -fluoro and 2 ,3 -difluoro analogues of pyrimidine deoxyribonucleosides have been synthesized and evaluated against human immunodeficiency virus (HIV-1) in a human lymphoblastoid cell line. Among these compounds, 1-(2,3-dideoxy-2-fluoro-beta-D-threopentofuranosyl)cytosine (12), 2 ,3 -didehydro-2 ,3 -dideo


Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides.
J Med Chem. 1990 Aug;33(8):2150-7. Unique Identifier : AIDSLINE MED/90325206
Sterzycki RZ; Ghazzouli I; Brankovan V; Martin JC; Mansuri MM; Department of Antiinfective Chemistry, Bristol-Myers Squibb Co.,; Wallingford, Connecticut 06492-7660.
Several 2 -fluoroarabino-2 ,3 -dideoxy- and 2 -fluoro-2 ,3 -unsaturated 2 ,3 -dideoxy pyrimidine nucleoside analogues are reported. The saturated analogues 1-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)thymine (2 -threo-FddT, 33), 1-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)uracil (2 -threo-FddU, 22) wer


Synthesis and antiviral activity of some acyclic and C-acyclic pyrrolo[2,3-d]pyrimidine nucleoside analogues.
J Med Chem. 1990 Aug;33(8):2162-73. Unique Identifier : AIDSLINE MED/90325208
Bennett SM; Nguyen-Ba N; Ogilvie KK; Department of Chemistry, McGill University, Montreal, Canada.
A series of acyclic and C-acyclic 7-deazapurine nucleosides have been synthesized and tested for antiviral activity. Reaction of the sodium salt of 2-amino-3,4-bis(aminocarbonyl)-5-(methylthio)pyrrole (6) with an appropriate electrophile gave pyrrole nucleosides which served as common intermediates to both the 7-deaza


Bilateral synchronous testis tumors of different histology in a patient with the acquired immunodeficiency syndrome related complex [see comments]
J Urol. 1990 Aug;144(2 Pt 1):353-5. Unique Identifier : AIDSLINE MED/90325351
Roehrborn CG; Worrell JT; Wiley EL; Division of Urology and Surgical Pathology, University of Texas; Southwestern Medical Center, Dallas.
The incidence of bilateral testis tumors is approximately 1.5%. Of these cases the majority have the same histological status and few occur synchronously. Recently, an increased number of nonseminomatous germ cell tumors have been reported in the acquired immunodeficiency syndrome population. We describe a rare case o


[Positive clinical effect of autologous transfusion of photomodified blood in the treatment of a patient with AIDS]
Vestn Khir Im I I Grek. 1990 Jan;144(1):55-7. Unique Identifier : AIDSLINE MED/90327647
Dvaladze NA; Belokurov VA; Gvaramiia GS; Gamkrelidze PS; Kirgan VI; Kosian AV; Melamud GIa; Mereshko IuN; Golovin GV
Risky business: using necessarily imprecise casualty counts to estimate occupational risks for HIV-1 infection.
Infect Control Hosp Epidemiol. 1990 Jul;11(7):371-9. Unique Identifier : AIDSLINE MED/90330827
Beekmann SE; Fahey BJ; Gerberding JL; Henderson DK; Hospital Epidemiology Service, National Institutes of Health,; Bethesda, MD 20892.
Although the genesis of healthcare worker anxiety regarding occupational risks of HIV-1 infection is clear, the reasons for continued insistence on a meticulous casualty count become less clear with time. One could, in fact, argue that the precise number of such infections has become virtually meaningless, because the


Effect of Mycobacterium leprae's phenolic glycolipid-I on interferon-gamma augmentation of monocyte oxidative responses.
Int J Lepr Other Mycobact Dis. 1990 Jun;58(2):342-6. Unique Identifier : AIDSLINE MED/90330868
Vachula M; Holzer TJ; Kizlaitis L; Andersen BR; Department of Medicine, University of Illinois, Chicago.
Peripheral blood monocytes were pretreated with phenolic glycolipid-I (PGL-I), dimycocerosyl phthiocerol (DIM), or mycoside A, then cultured in the presence or absence of interferon-gamma (IFN-gamma). Their oxidative responses to Mycobacterium leprae, phorbol myristate acetate (PMA), and opsonized zymosan were evaluat


Pathology of dual Mycobacterium leprae and simian immunodeficiency virus infection in rhesus monkeys.
Int J Lepr Other Mycobact Dis. 1990 Jun;58(2):358-64. Unique Identifier : AIDSLINE MED/90330871
Baskin GB; Gormus BJ; Martin LN; Murphey-Corb M; Walsh GP; Meyers WM; Department of Pathology, Delta Regional Primate Research Center,; Tulane University, Covington, Louisiana 70433.
Three rhesus monkeys were experimentally inoculated with sooty-mangabey-derived Mycobacterium leprae and were inadvertently infected with the simian immunodeficiency virus (SIV) as well. They died of an immunodeficiency syndrome, and at autopsy all had lesions caused by M. leprae. One monkey was inoculated twice with


Prevention and control of tuberculosis in facilities providing long-term care to the elderly. Recommendations of the Advisory Committee for Elimination of Tuberculosis.
MMWR Morb Mortal Wkly Rep. 1990 Jul 13;39(RR-10):7-13. Unique Identifier : AIDSLINE MED/90331910
Severe chronic active Epstein-Barr virus infection syndrome and adenovirus type-2 infection.
Am J Pediatr Hematol Oncol. 1990 Summer;12(2):168-73. Unique Identifier : AIDSLINE MED/90334252
Okano M; Thiele GM; Purtilo DT; Department of Pathology, University of Nebraska Medical Center,; Omaha 68105-1065.
Four patients from 4 to 24 years of age (3 males, 1 female) with generalized lymphadenopathy, hepatosplenomegaly, and intermittent fever associated with chronic active Epstein-Barr virus (EBV) infection were investigated. Laboratory data showed polyclonal gammopathy and a tendency for bone marrow suppression. Notewort


Epstein-Barr virus infection in Chediak-Higashi syndrome mimicking acute lymphocytic leukemia.
Am J Pediatr Hematol Oncol. 1990 Summer;12(2):182-6. Unique Identifier : AIDSLINE MED/90334254
Kinugawa N; Department of Pediatrics, Tokyo Metropolitan Maternity and Child; Health Institute, Japan.
We have had the opportunity to study a case of Chediak-Higashi syndrome (CHS) in the accelerated phase that was associated with Epstein-Barr virus (EBV) infection. The clinical course of a 12-year-old boy was characterized by fever, lymphadenopathy, hepatosplenomegaly, and pancytopenia. However, in the terminal stage,


Interleukin-2 effects in the central nervous system.
Ann N Y Acad Sci. 1990;594:188-99. Unique Identifier : AIDSLINE MED/90334386
Merrill JE; Department of Neurology, Reed Neurological Research Center, UCLA; School of Medicine 90024.
Gallium scintigraphy in AIDS.
Med J Aust. 1990 Jul 2;153(1):14-20. Unique Identifier : AIDSLINE MED/90340188
Van der Wall H; Murray IP; Jones PD; Dwyer JM; Prince of Wales Hospital, Randwick, NSW.
The acquired immunodeficiency syndrome (AIDS) is a growing problem in Australia : 438 new cases were added in 1988, resulting in the cumulative total of 1562 patients up to November 1989. The cumulative death rate stands at 54%, the majority of deaths being due to secondary infec


Differential expression of hydrogen uptake (hup) genes in vegetative and symbiotic cells of Rhizobium leguminosarum.
Mol Gen Genet. 1990 May;221(3):363-70. Unique Identifier : AIDSLINE MED/90340287
Palacios JM; Murillo J; Leyva A; Ditta G; Ruiz-Argueso T; Laboratorio de Microbiologia, Escuela Tecnica Superior de; Ingenieros Agronomos, Madrid, Spain.
The genetic determinants responsible for H2-uptake (hup genes) in Rhizobium leguminosarum are organized in six transcriptional units, designated regions hupI to hupVI, with region hupI coding for the hydrogenase structural genes (Leyva et al. 1990). Regulation of the expression of hup genes from R. leguminosarum was e


Affinity-based collection of amplified viral DNA: application to the detection of human immunodeficiency virus type 1, human cytomegalovirus and human papillomavirus type 16.
Mol Cell Probes. 1990 Jun;4(3):223-35. Unique Identifier : AIDSLINE MED/90340332
Harju L; Janne P; Kallio A; Laukkanen ML; Lautenschlager I; Mattinen S; Ranki A; Ranki M; Soares VR; Soderlund H; et al; Orion Pharmaceutica, Biotechnology, Helsinki, Finland.
We have devised a sensitive and convenient hybridization technique by combining the polymerase chain reaction (PCR) with affinity-based hybrid collection. In this method 5 -biotinylated primers are used to introduce biotin residues into the DNA fragments during the amplification. The amplified DNA fragments are detect


Court upholds disclosure of HIV test results of hospital employee.
Pa Nurse. 1990 Jul;45(7):1, 3. Unique Identifier : AIDSLINE MED/90340859
Navran SH
Health field AIDS rate underestimated [interview]
Pa Nurse. 1990 Aug;45(8):20. Unique Identifier : AIDSLINE MED/90340868
Bell D
U.K. vaccine trial: stalking horse for the future [news]
Science. 1990 Aug 10;249(4969):626. Unique Identifier : AIDSLINE MED/90341790
Cherfas J
Rectal small cell cancer in an HIV-positive man.
Am J Med. 1990 Aug;89(2):239-40. Unique Identifier : AIDSLINE MED/90342772
Smitherman MH; Morris LE Jr; Chang BK; Khankhanian NK; Dunlap DB; Department of Medicine, Veterans Administration Medical Center,; Augusta, Georgia 30910.
Latex and vinyl nonsterile examination gloves: status report on laboratory evaluation of defects by physical and biological methods [published erratum appears in Appl Environ Microbiol 1990 Nov;56(11):3627]
Appl Environ Microbiol. 1990 Jun;56(6):1627-30. Unique Identifier : AIDSLINE MED/90343319
Kotilainen HR; Avato JL; Gantz NM; Infection Control Department, University of Massachusetts Medical; Center, Worcester 01655.
We have reported previously (H. R. Kotilainen, J. P. Brinker, J. L. Avato, and N. M. Gantz, Arch. Intern. Med. 149:2749-2753, 1989) that the quality of nonsterile examination gloves available for clinical use may be extremely variable. In view of the concern over human immunodeficiency virus and hepatitis B virus tran


Varicella in patients infected with the human immunodeficiency virus [see comments]
Arch Dermatol. 1990 Aug;126(8):1033-6. Unique Identifier : AIDSLINE MED/90343374
Perronne C; Lazanas M; Leport C; Simon F; Salmon D; Dallot A; Vilde JL; Service des Maladies Infectieuses et Tropicales, Hopital; Claude-Bernard, Paris, France.
In a retrospective study of 421 patients infected with human immunodeficiency virus, 15 (3.5%) had varicella. Twelve patients had a typical varicella. Complications were as follows: profuse eruption, 6; hemorrhagic eruption, 1; hepatitis, 5; and pulmonary involvement, 1; 1 patient developed an intravascular disseminat


Prolonged cutaneous herpes zoster in acquired immunodeficiency syndrome [see comments]
Arch Dermatol. 1990 Aug;126(8):1048-50. Unique Identifier : AIDSLINE MED/90343379
Hoppenjans WB; Bibler MR; Orme RL; Solinger AM; Department of Dermatology, University of Cincinnati, Ohio,; College of Medicine.
We described the development of prolonged disseminated cutaneous herpes zoster in two patients with acquired immunodeficiency syndrome. Both patients developed hyperkeratotic, verrucous lesions that progressed despite acyclovir therapy. The biopsy specimens were typical of herpe


Use of potentially infected donor hearts for cardiac transplantation.
Ann Thorac Surg. 1990 Aug;50(2):222-5. Unique Identifier : AIDSLINE MED/90343499
Lammermeier DE; Sweeney MS; Haupt HE; Radovancevic B; Duncan JM; Frazier OH; Division of Cardiovascular Surgery, Texas Heart Institute,; Houston.
Despite the nationwide shortage of heart donors, more patients, some of whom are critically ill, are being accepted as candidates for transplantation. Thus, on occasion, we have liberalized our donor criteria to meet the demand. We have recently transplanted 16 potentially infected donor hearts into critically ill rec


Acute ulcerative proctocolitis associated with primary cytomegalovirus infection.
Arch Intern Med. 1990 Aug;150(8):1749-51. Unique Identifier : AIDSLINE MED/90343600
Diepersloot RJ; Kroes AC; Visser W; Jiwa NM; Rothbarth PH; Department of Virology, University Hospital Dijkzigt, Rotterdam,; The Netherlands.
The case is reported of a 39-year-old pregnant woman who presented with fever, abdominal complaints, and diarrhea. Laboratory investigation revealed mononucleosis in the peripheral blood. All microbiological studies were negative, with the exception of finding cytomegalovirus (


Detection of locally produced antibodies to herpes viruses in the aqueous of patients with acquired immune deficiency syndrome (AIDS) or acute retinal necrosis syndrome (ARN).
Curr Eye Res. 1990;9 Suppl:7-11. Unique Identifier : AIDSLINE MED/90345714
Luyendijk L; v.d. Horn GJ; Visser OH; Suttorp-Schulten MS; v.d. Biesen PR; Rothova A; Kijlstra A; Department of Ophthalmo-Immunology, The Netherlands Ophthalmic; Research Institute.
Intraocular synthesis of IgG antibodies against HSV (herpes simplex virus), CMV ( cytomegalovirus ) and VZV (varicella zoster virus) is considered as an indirect proof of uveoretinal infection. Paired serum and aqueous samples


Immune status as a determinant of human papillomavirus detection and its association with anal epithelial abnormalities.
Int J Cancer. 1990 Aug 15;46(2):203-6. Unique Identifier : AIDSLINE MED/90346447
Melbye M; Palefsky J; Gonzales J; Ryder LP; Nielsen H; Bergmann O; Pindborg J; Biggar RJ; Danish Cancer Registry, Institute of Cancer Epidemiology,; Copenhagen.
One hundred and twenty Danish homosexual men were enrolled to characterize risk factors for anal type-specific human papillomavirus (HPV) expression and to examine its association with anal epithelial atypia. Detection of HPV strongly correlated with immunosuppression measured by T-lymphocyte subset markers and rose n


Interaction of human immunodeficiency and papilloma viruses: association with anal epithelial abnormality in homosexual men.
Int J Cancer. 1990 Aug 15;46(2):214-9. Unique Identifier : AIDSLINE MED/90346449
Caussy D; Goedert JJ; Palefsky J; Gonzales J; Rabkin CS; DiGioia RA; Sanchez WC; Grossman RJ; Colclough G; Wiktor SZ; et al; Viral Epidemiology Section, NCI, Rockville, MD 20852.
During the 7th annual follow-up of our cohort of homosexual men in 1989, we tested the hypotheses that infection with human immunodeficiency virus (HIV) may enhance the expression of human papilloma virus (HPV) and that the development of anal epithelial abnormality is related to a biologic interaction between these t


The production and purification of PCR-derived recombinant simian immunodeficiency virus p27 gag protein; its use in detecting serological and T-cell responses in macaques [published erratum appears in J Virol Methods 1990 Nov;30(2):229]
J Virol Methods. 1990 Jun;28(3):305-19. Unique Identifier : AIDSLINE MED/90347029
Almond N; Page M; Mills K; Jenkins A; Ling C; Thorpe R; Kitchin P; Williams M; Collaborative Centre for AIDS, National Institute for Biological; Standards and Control, South Mimms, Potters Bar, U.K.
The polymerase chain reaction (PCR) was used to amplify a region of the gag gene, encompassing the core protein p27, from genomic DNA of cells infected with SIVmac251 (32H isolate). The 767 base pair PCR product was cloned into the bacteriophage M13 and fully sequenced before sub-cloning into the expression vector pUC


HIV DNA integration: observations and interferences.
J Acquir Immune Defic Syndr. 1990;3(9):839-51. Unique Identifier : AIDSLINE MED/90347667
Kulkosky J; Skalka AM; Fox Chase Cancer Center, Institute for Cancer Research,; Philadelphia, Pennsylvania 19111.
DNA integration appears to be an obligatory step for the efficient replication of retroviruses. Studies of the integration reaction for the avian and murine C-type retroviruses have defined the importance of: i) LTR terminal sequences, which are joined to host DNA, and ii) the activity of the retroviral integration pr


Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms.
J Acquir Immune Defic Syndr. 1990;3(9):873-6. Unique Identifier : AIDSLINE MED/90347670
Fuchs D; Moller AA; Reibnegger G; Stockle E; Werner ER; Wachter H; Institute of Medical Chemistry and Biochemistry, University of; Innsbruck, Austria.
We investigated serum neopterin, tryptophan, and kynurenine concentrations in 23 HIV-1 seropositive patients (Walter Reed Stage 4-6). Ten patients presented with polyneuropathy and three with dementia , one of the patients with dementia also had polyneuropathy and dementia. We found


Cervical cytologic abnormalities and papillomavirus in women infected with human immunodeficiency virus.
J Acquir Immune Defic Syndr. 1990;3(9):896-903. Unique Identifier : AIDSLINE MED/90347674
Feingold AR; Vermund SH; Burk RD; Kelley KF; Schrager LK; Schreiber K; Munk G; Friedland GH; Klein RS; Department of Epidemiology and Social Medicine, Montefiore; Medical Center/Albert Einstein College of Medicine, Bronx, New; York 10461.
We investigated the relationship of human papillomavirus (HPV) infection of the female genital tract, cervical cytology, and human immunodeficiency virus (HIV) infection in 67 women. Forty-eight women had a history of intravenous drug use, 18 were heterosexual partners of HIV-infected intravenous drug users, and one w


Incorporation of chimeric gag protein into retroviral particles.
J Virol. 1990 Sep;64(9):4169-79. Unique Identifier : AIDSLINE MED/90347809
Weldon RA Jr; Erdie CR; Oliver MG; Wills JW; Department of Biochemistry and Molecular Biology, Louisiana State; University Medical Center-Shreveport 71130.
The product of the Rous sarcoma virus (RSV) gag gene, Pr76gag, is a polyprotein precursor which is cleaved by the viral protease to yield the major structural proteins of the virion during particle assembly in avian host cells. We have recently shown that myristylated forms of the RSV Gag protein can induce particle f


Characterization and significance of delayed processing of the feline leukemia virus FeLV-FAIDS envelope glycoprotein.
J Virol. 1990 Sep;64(9):4338-45. Unique Identifier : AIDSLINE MED/90347829
Poss ML; Quackenbush SL; Mullins JI; Hoover EA; Department of Pathology, College of Veterinary Medicine and; Biomedical Sciences, Colorado State University, Fort Collins; 80523.
FeLV-FAIDS, an immunodeficiency-inducing isolate of feline leukemia virus, is composed of a pathogenic but replication-defective genome (molecular clone 61C) and a replication-competent but non-immunodeficiency-inducing variant genome (molecular clone 61E). The chimeric virus EECC, composed of the 5 gag-pol of 61E fu


Differential expression in human and mouse cells of human immunodeficiency virus pseudotyped by murine retroviruses.
J Virol. 1990 Sep;64(9):4553-7. Unique Identifier : AIDSLINE MED/90347855
Chesebro B; Wehrly K; Maury W; Laboratory of Persistent Viral Disease, Rocky Mountain; Laboratories, National Institute of Allergy and Infectious; Diseases, Hamilton, Montana 59840.
Expression of cell surface CD4 influences susceptibility of cells to human immunodeficiency virus (HIV) infection; however, some CD4-positive human and mouse cells are still resistant to HIV infection. To search for mechanisms of resistance to HIV independent of CD4 expression, HIV expression was studied in human and


CDC ponders new HIV guidelines [news]
JAMA. 1990 Sep 5;264(9):1079. Unique Identifier : AIDSLINE MED/90347866
Goldsmith MF
Altered mitogen response of peripheral blood lymphocytes in different stages of feline immunodeficiency virus infection.
Nippon Juigaku Zasshi. 1990 Jun;52(3):513-8. Unique Identifier : AIDSLINE MED/90348050
Taniguchi A; Ishida T; Konno A; Washizu T; Tomoda I; Department of Clinical Pathology, Nippon Veterinary and; Zootechnical College, Tokyo, Japan.
To elucidate relationship between disease progress and immunologic alteration in feline immunodeficiency virus (FIV) infection, we classified naturally infected cats into clinical stage groups using the working criteria modified from those for human immunodeficiency virus (HIV) infection. Among the five distinct stage


Clinical staging of feline immunodeficiency virus infection.
Nippon Juigaku Zasshi. 1990 Jun;52(3):645-8. Unique Identifier : AIDSLINE MED/90348069
Ishida T; Tomoda I; Department of Clinical Pathology, Nippon Veterinary and; Zootechnical College, Tokyo, Japan.
Value of 67gallium scintigraphy in primary diagnosis and follow-up of opportunistic pneumonia in patients with AIDS.
Lung. 1990;168 Suppl:692-703. Unique Identifier : AIDSLINE MED/90348360
Moser E; Tatsch K; Kirsch CM; Kuffer G; Goebel FD; Department of Radiology, University of Freiburg, Federal Republic; of Germany.
Opportunistic pneumonias are a life-threatening complication in patients with AIDS. Early diagnosis and therapy is necessary to improve the prognosis. This study was designed to assess the value of 67gallium scintigraphy in the primary detection and follow-up of these special pneumonias. 67Gallium scintigraphy was per


2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine.
Mol Pharmacol. 1990 Aug;38(2):237-43. Unique Identifier : AIDSLINE MED/90348637
Tornevik Y; Eriksson S; Department of Biochemistry I, Karolinska Institute, Stockholm,; Sweden.
2 ,3 -Dideoxycytidine (ddCyd), a potent inhibitor of human immunodeficiency virus DNA replication, requires phosphorylation by cellular nucleoside kinases for antiviral activity. Deoxycytidine kinase (NTP:deoxycytidine 5 -phosphotransferase, EC 2.7.1.74) is responsible for the formation of dideoxycytidine monophosphat


Overview of phase I trials of 2',3'-dideoxyinosine (ddI) conducted on adult patients.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S570-5. Unique Identifier : AIDSLINE MED/90349978
Rozencweig M; McLaren C; Beltangady M; Ritter J; Canetta R; Schacter L; Kelley S; Nicaise C; Smaldone L; Dunkle L; et al; Bristol-Myers Squibb Company, Pharmaceutical Research and; Development Division, Wallingford, Connecticut 06492-7660.
Ninety-two adult patients with AIDS or severe AIDS-related complex were treated with 2 ,3 -dideoxyinosine (didanosine; ddI) at dosages ranging from 0.8 to 66.0 mg/(kg.d) for at least 6 weeks in phase I trials. Potentially beneficial changes in weight (40% of patients), clinical signs or symptoms (40% of patients), CD4


1989 sexually transmitted diseases treatment guidelines. Introduction.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 6:S577-9. Unique Identifier : AIDSLINE MED/90349980
Zenilman JM; Cates W Jr; Division of Sexually Transmitted Diseases and HIV Prevention,; Centers for Disease Control, Atlanta, Georgia.
Treatment of genital herpes.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 6:S610-9. Unique Identifier : AIDSLINE MED/90349983
Stone KM; Whittington WL; Division of Sexually Transmitted Diseases, Centers for Disease; Control, Atlanta, Georgia 30333.
Oral acyclovir has been used successfully to treat and prevent symptomatic episodes of genital herpes simplex virus infection. Daily suppressive therapy has proven to be safe and effective when used continuously for periods as long as 4 ye


Altered immunoregulation and autoimmune aspects of HIV infection: relevant murine models.
Immunol Today. 1990 Jul;11(7):250-5. Unique Identifier : AIDSLINE MED/90351546
Via CS; Morse HC 3d; Shearer GM; Division of Rheumatology and Clinical Immunology, University of; Maryland School of Medicine and Research Service, Loch Raven VA; Medical Center, Baltimore 21201.
After initial infection with human immunodeficiency virus 1 (HIV-1), patients may remain asymptomatic for years before the onset of acquired immune deficiency syndrome (AIDS). This non-aggressive or latent phase may be manifested by functional abnormalities of both T and B cells, even in the absence of critical reduct


Emergence of acyclovir-resistant varicella zoster virus in an AIDS patient on prolonged acyclovir therapy.
AIDS. 1990 Jun;4(6):577-9. Unique Identifier : AIDSLINE MED/90351574
Linnemann CC Jr; Biron KK; Hoppenjans WG; Solinger AM; Department of Medicine, University of Cincinnati College of; Medicine, Ohio 45267-0560.
We demonstrate for the first time the appearance of acyclovir resistance in serial varicella zoster isolates from a patient treated with acyclovir. We recovered varicella zoster virus three times over a period of 5 months from the skin lesions of this patient with AIDS who was t


Histoplasmosis in a UK patient treated with itraconazole [letter]
AIDS. 1990 Jun;4(6):602-3. Unique Identifier : AIDSLINE MED/90351583
Youle M; Nelson M; Midgley J; Rowe I; Campbell C; Gazzard B
Statistics from the World Health Organization and the Centers for Disease Control.
AIDS. 1990 Jun;4(6):605-10. Unique Identifier : AIDSLINE MED/90351584
Acquired immunodeficiency syndrome (AIDS). Recommendations for the interpretation of HIV-2 western blot results.
Wkly Epidemiol Rec. 1990 Mar 9;65(10):74-5. Unique Identifier : AIDSLINE MED/90352072
Composite Hodgkin's and non-Hodgkin's lymphoma in a patient with acquired immune deficiency syndrome. In-situ demonstration of Epstein-Barr virus.
Cancer. 1990 Aug 15;66(4):796-800. Unique Identifier : AIDSLINE MED/90352513
Guarner J; del Rio C; Hendrix L; Unger ER; Department of Pathology and Laboratory Medicine, Emory; University, Atlanta, GA 30322.
A 44-year-old man infected with human immunodeficiency virus had Hodgkin s disease, mixed cellularity, and malignant non-Hodgkin s lymphoma , diffuse large cell type. Colorimetric in-situ hybridization showed the Epstein-Barr virus (EBV) genome in the cells of the large cell non-Hod


Murine models for evaluating antiretroviral therapy.
Cancer Res. 1990 Sep 1;50(17 Suppl):5618S-5627S. Unique Identifier : AIDSLINE MED/90352613
Ruprecht RM; Bernard LD; Gama Sosa MA; Sosa MA; Fazely F; Koch J; Sharma PL; Mullaney S; Division of Cancer Pharmacology, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115.
The pandemic of the acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency virus type 1 (HIV-1), requires rapid development of effective therapy and prevention. Analysis of candidate anti-HIV-1 drugs in animals is problematic since no ideal animal model for HIV-1 infection and disease exists.


Endogenous retroviral elements in human DNA.
Cancer Res. 1990 Sep 1;50(17 Suppl):5636S-5642S. Unique Identifier : AIDSLINE MED/90352616
Leib-Mosch C; Brack-Werner R; Werner T; Bachmann M; Faff O; Erfle V; Hehlmann R; III. Medizinische Klinik Mannheim, Universitat Heidelberg,; Mannheim, Federal Republic of Germany.
Endogenous retroviruses and retroviral elements represent a substantial component of vertebrate genomes. They are inherited as stable Mendelian genes and may be activated spontaneously or by physical or chemical agents. In the human genome various retroviral elements have been detected by their relationship with mamma


Subunit vaccine protects Macaca nemestrina (pig-tailed macaque) against simian T-cell lymphotropic virus type I challenge.
Cancer Res. 1990 Sep 1;50(17 Suppl):5687S-5691S. Unique Identifier : AIDSLINE MED/90352626
Dezzutti CS; Frazier DE; Huff LY; Stromberg PC; Olsen RG; Center for Retrovirus Research, Columbus, Ohio 43210.
Five macaques received two vaccinations consisting of soluble human T-cell lymphotropic virus type I proteins from a cell/serum-free human T-cell lymphotropic virus type I-producing cell line. Five other macaques were vaccine controls. All were challenged with a simian T-cell lymphotropic virus type I-producing cell l


Chromosome and gene rearrangements in immortalized human lymphocytes infected with human T-lymphotropic virus type I.
Cancer Res. 1990 Sep 1;50(17 Suppl):5697S-5702S. Unique Identifier : AIDSLINE MED/90352628
Maruyama K; Fukushima T; Kawamura K; Mochizuki S; Department of Pathology, Chiba Cancer Center Research Institute,; Japan.
Karyotypes of 26 human lymphocyte cultures, infected or noninfected with human T-lymphotropic virus type I (HTLV-I), with or without Epstein-Barr virus infection, were analyzed by G-banding. Hypodiploidy and structural abnormalities were seen more frequently in HTLV-I-infected cultures (30%) than in virus noninfected


Assessment of the potential malignancy of Epstein-Barr virus (EBV)-infected B cells in AIDS-related disorders.
Cancer Detect Prev. 1990;14(3):325-9. Unique Identifier : AIDSLINE MED/90352633
Roncella S; Caretto P; Forni G; Cutrona G; Verde A; Ramarli D; de Celle PF; Foa R; Sessarego M; Pistoia V; et al; Servizio de Immunologia Clinica, Istituto Nazionale per la; Ricerca sul Cancro, Genova, Italy.
Spontaneous lymphoblastoid cell lines (LCLs) were established from the peripheral blood of ten human immunodeficiency virus (HIV)-seropositive patients in order to investigate whether or not a progression of the cells toward a malignant state could be traced. The LCLs studied displayed no differences in their surface


Possible cofactors for the development of AIDS-related neoplasms.
Cancer Detect Prev. 1990;14(3):331-6. Unique Identifier : AIDSLINE MED/90352634
Holmberg SD; AIDS Program, Centers for Disease Control, Atlanta, GA 30333.
Because of the various neoplastic manifestations of human immunodeficiency virus (HIV) and the variable period between HIV infection and the development of tumors related to acquired immunodeficiency syndrome (AIDS), it is possible that certain behaviors, toxins, genes, or infectious agents--particularly viruses--may


Cytomegalovirus (CMV) titers among acquired immunodeficiency syndrome (AIDS) patients with and without a history of Kaposi's sarcoma (KS).
Cancer Detect Prev. 1990;14(3):337-42. Unique Identifier : AIDSLINE MED/90352635
Johnston GS; Jockusch J; McMurtry LC; Shandera WX; Department of Medicine, Ben Taub Hospital, Houston, TX 77030.
The relationship between a history of Kaposi s sarcoma (KS) and serum titers to cytomegalovirus ( CMV ) among homosexual patients with acquired immunodeficiency syndrome (AIDS) was studied. Individuals with a history of AIDS an


Significance of viral coinfections by HIV, HTLV-I, Epstein-Barr virus, and cytomegalovirus for immunological abnormalities in hemophiliacs.
Cancer Detect Prev. 1990;14(3):343-6. Unique Identifier : AIDSLINE MED/90352636
Okubo S; Yasunaga K; First Department of Internal Medicine, Kansai Medical University,; Osaka, Japan.
In order to clarify the influence of viral coinfection on the immunological abnormalities of hemophiliacs infected with human immunodeficiency virus (HIV), 69 patients were examined. Of the 69, 35 (50.7%) were HIV-antibody positive (HIV-Ab+). Two of them were acquired immunodeficiency syndrome (AIDS) and the remaining


Management of cytomegalovirus infection in patients with acquired immunodeficiency syndrome.
Clin Pharm. 1990 Aug;9(8):613-31. Unique Identifier : AIDSLINE MED/90352933
Pau AK; Pitrak DL; Department of Pharmacy Practice, College of Pharmacy, University; of Illinois, Chicago 60612.
The clinical manifestations of cytomegalovirus ( CMV ) infection in persons with AIDS are described, and recent advances in the management of these syndromes with antiviral agents are reviewed. CMV infection is the most common


Detection of herpes viral genomes in normal and diseased corneal epithelium.
Curr Eye Res. 1990 Jun;9(6):569-81. Unique Identifier : AIDSLINE MED/90353005
Crouse CA; Pflugfelder SC; Pereira I; Cleary T; Rabinowitz S; Atherton SS; Bascom Palmer Eye Institute, Department of Ophthalmology, Miami,; FL.
Herpetic ocular disease is one of the major causes of corneal blindness. Clinical diagnosis of corneal disease is based principally on corneal appearance. However, abnormal morphology of the corneal epithelium (CE) is not an indicator for the presence of a herpes virus. Further, it has not been established if herpes v


Protocols for managing personnel exposed to infectious disease.
Dent Manage. 1990 Feb;30(2):40-2, 44, 46. Unique Identifier : AIDSLINE MED/90353686
Stout FW; University of Florida's College of Dentistry.
Endogenous carbohydrate-binding proteins in Pneumocystis carinii.
Infect Immun. 1990 Sep;58(9):3143-6. Unique Identifier : AIDSLINE MED/90354092
Vierbuchen M; Ortmann M; Uhlenbruck G; Institute of Pathology, University of Cologne, Federal Republic; of Germany.
By using biotinylated neoglycoproteins, the in situ occurrence of endogenous carbohydrate-binding proteins (lectins) in Pneumocystis carinii has been glycohistochemically demonstrated in lung tissue specimens from acquired immunodeficiency syndrome patients with P. carinii pneumonia. While the parasite possessed only


Coinfection with A- and B-type Epstein-Barr virus in human immunodeficiency virus-positive subjects.
J Infect Dis. 1990 Sep;162(3):643-8. Unique Identifier : AIDSLINE MED/90354703
Sculley TB; Apolloni A; Hurren L; Moss DJ; Cooper DA; Queensland Institute of Medical Research, Brisbane.
A possible cofactor in human immunodeficiency virus (HIV) infection is the Epstein-Barr virus (EBV), which is divided into two primary types that differ significantly in their transformation efficiency. The B-type EBV cell line is much more difficult to establish than the A-type. The extent of systemic B-type EBV infe


Azoles and AIDS.
J Infect Dis. 1990 Sep;162(3):727-30. Unique Identifier : AIDSLINE MED/90354717
Larsen RA; Department of Medicine, University of Southern California Medical; Center, Los Angeles.
The treatment of opportunistic infections in AIDS patients is changing rapidly as new drugs become available and new studies of old drugs are completed. I have tried to use the AIDS commentaries to keep up with these advances. Since fluconazole has just recently been approved by the US Food and Drug Administration, I


Altered sensitivity to antiviral drugs of herpes simplex virus isolates from a patient with the acquired immunodeficiency syndrome.
J Infect Dis. 1990 Sep;162(3):731-4. Unique Identifier : AIDSLINE MED/90354718
Birch CJ; Tachedjian G; Doherty RR; Hayes K; Gust ID; Virology Department, Fairfield Hospital, Australia.
Acyclovir (ACV)-resistant herpes simplex virus type 2 (HSV-2) was isolated from a patient with acquired immunodeficiency syndrome after long-term but intermittent ACV therapy. These thymidine kinase-defective isolates were sensitive in vitro to foscarnet. While combined therapy


High levels of Epstein-Barr virus in the oropharynx: a predictor of disease progression in human immunodeficiency virus infection.
J Med Virol. 1990 Jun;31(2):69-75. Unique Identifier : AIDSLINE MED/90354819
Diaz-Mitoma F; Ruiz A; Flowerdew G; Houston S; Romanowski B; Kovithavongs T; Preiksaitis J; Tyrrell DL; Department of Medical Microbiology & Infectious Diseases,; University of Alberta, Edmonton, Canada.
The role of Epstein-Barr virus (EBV) on the progression of human immunodeficiency virus (HIV) infection is not well defined. The objective of this prospective study was to determine the prevalence of EBV excretion and the role that EBV might have on HIV disease progression. Fifty-two homosexual males were studied, all


[Endocrine abnormalities in HIV infections]
Presse Med. 1990 Jul 7-14;19(27):1267-70. Unique Identifier : AIDSLINE MED/90356504
Verges B; Chavanet P; Desgres J; Kisterman JP; Waldner A; Vaillant G; Portier H; Brun JM; Putelat R; Service de medecine 2 (Medecine interne-Endocrinologie), Centre; Hospitalier et Universitaire, Hopital du Bocage, Dijon.
The finding of endocrine gland lesions at pathological examination in AIDS and reports of several cases of endocrine disease in patients with this syndrome have prompted us to study endocrine functions in 63 patients (51 men, 12 women) with HIV-1 infection. According to the Center for Disease Control (CDC) classificat


[Feline immunodeficiency virus in Switzerland: clinical aspects and epidemiology in comparison with feline leukemia virus and coronaviruses]
Schweiz Arch Tierheilkd. 1990;132(5):217-25. Unique Identifier : AIDSLINE MED/90357014
Lutz H; Lehmann R; Winkler G; Kottwitz B; Dittmer A; Wolfensberger C; Arnold P; Veterinar-Medizinische Klinik der Universitat Zurich.
Serum samples from 1421 domestic cats (561 healthy, 860 sick) were tested for FIV-, FeLV- and coronavirus infection. The results were stored in a computer data base and compared with epidemiologic data and clinical findings. All 3 infections were significantly more prevalent in sick than healthy cats: FIV was found in


AIDS--the leading cause of adult death in the West African City of Abidjan, Ivory Coast.
Science. 1990 Aug 17;249(4970):793-6. Unique Identifier : AIDSLINE MED/90357031
De Cock KM; Barrere B; Diaby L; Lafontaine MF; Gnaore E; Porter A; Pantobe D; Lafontant GC; Dago-Akribi A; Ette M; et al; Center for Infectious Diseases, Centers for Disease Control,; Atlanta, GA 30333.
In 1988 to 1989, 698 adult cadavers in Abidjan s two largest morgues were studied, representing 38 to 43% of all adult deaths in the city over the study period, and 6 to 7% of annual deaths. Forty-one percent of male and 32% of female cadavers were infected with human immunodeficiency virus (HIV). Fifteen percent of a


Subcellular localization of rev-gene product in visna virus-infected cells.
Virology. 1990 Sep;178(1):305-10. Unique Identifier : AIDSLINE MED/90357781
Mazarin V; Gourdou I; Querat G; Sauze N; Audoly G; Vitu C; Russo P; Rousselot C; Filippi P; Vigne R; Laboratoire de Virologie, Faculte de Medecine Nord, Marseille,; France.
The 1.4-kb mRNA of visna lentivirus is expressed early during the lytic infection of sheep choroid plexus cell cultures. It encodes for visna early gene 1 (VEG1) product, since renamed rev gene product (or Rev), based on significant amino acid sequence homologies between this protein and the proteins of simian immunod


[Herpesvirus-6--a new human virus (editorial)]
Vopr Virusol. 1990 Mar-Apr;35(2):171-2. Unique Identifier : AIDSLINE MED/90357824
The CD4 molecule and HIV infection.
Immunodefic Rev. 1990;2(1):43-66. Unique Identifier : AIDSLINE MED/90321561
Klatzmann DR; McDougal JS; Maddon PJ; Laboratoire de Biologie et Genetique des Infections; Retrovirales, Hopital de la Pitie Salpetriere, Paris,; France.
CD4 (T4), a glycoprotein expressed largely on the surface of cells in the immune system, serves as the receptor for the human immunodeficiency virus, HIV. The isolation of the CD4 gene has permitted an analysis of the structure of CD4 and its role in both HIV infection and the immune response. Recently, new classes of


Anal human papillomavirus infection among human immunodeficiency virus-seropositive and -seronegative men.
J Infect Dis. 1990 Aug;162(2):358-61. Unique Identifier : AIDSLINE MED/90324646
Kiviat N; Rompalo A; Bowden R; Galloway D; Holmes KK; Corey L; Roberts PL; Stamm WE; Department of Pathology, University of Washington School of; Medicine, Seattle.
Homosexual men are at high risk of anorectal human papillomavirus (HPV) infection, HPV-related anal cancer, and precancer, conditions known to increase with immunosuppression. The relationship between anal HPV infection, human immunodeficiency virus (HIV) infection, and immunosuppression was studied in homosexual men


The role of Neisseria gonorrhoeae and Chlamydia trachomatis in pelvic inflammatory disease and its sequelae in Zimbabwe.
J Infect Dis. 1990 Aug;162(2):501-5. Unique Identifier : AIDSLINE MED/90324668
De Muylder X; Laga M; Tennstedt C; Van Dyck E; Aelbers GN; Piot P; Provincial Hospital, Gweru, Zimbabwe.
The presence of antibodies to pili of Neisseria gonorrhoeae and Chlamydia trachomatis serovar L2 were assessed in women consecutively hospitalized in Zimbabwe with pelvic inflammatory disease (PID; n = 66), infertility (n = 227), and ectopic pregnancy (n = 60). Women delivering l


Candida albicans in patients with the acquired immunodeficiency syndrome: absence of a novel of hypervirulent strain.
J Infect Dis. 1990 Aug;162(2):513-8. Unique Identifier : AIDSLINE MED/90324670
Whelan WL; Kirsch DR; Kwon-Chung KJ; Wahl SM; Smith PD; Cellular Immunology Section, National Institute of Dental; Research, National Institutes of Health, Bethesda, MD 20892.
To determine whether Candida albicans in patients with AIDS represents a unique strain, C. albicans isolated from 24 patients with AIDS was compared with Candida isolated from 23 healthy adults. Resistance to 5-fluorocytosine, synthesis of amino acids and nucleotides, sugar use, and enzyme activity patterns were simil


Current and future dimensions of the HIV/AIDS pandemic in women and children.
Lancet. 1990 Jul 28;336(8709):221-4. Unique Identifier : AIDSLINE MED/90325892
Chin J; Global Programme on AIDS, World Health Organisation, Geneva,; Switzerland.
The WHO estimates that during the first decade of the HIV/AIDS pandemic there were about 500,000 cases of AIDS in women and children, most of which have been unrecognised. During the 1990s, WHO estimates that the pandemic will kill an additional 3 million or more women and children world wide. HIV infection among hete


Haemophilic AIDS patient loses claim in Australia [news]
Lancet. 1990 Jul 28;336(8709):238-9. Unique Identifier : AIDSLINE MED/90325896
Brahams D
Isolation of Mycoplasma incognitus [letter]
Lancet. 1990 Jul 28;336(8709):247. Unique Identifier : AIDSLINE MED/90325906
van der Riet F
Mycoplasma and AIDS [letter]
Lancet. 1990 Jul 28;336(8709):247-8. Unique Identifier : AIDSLINE MED/90325907
Chowdhury MI; Koyanagi Y; Kobayashi S; Yamamoto N; Munakata T; Arai S
Intrathecal zidovudine for AIDS dementia [letter] [see comments]
Lancet. 1990 Jul 28;336(8709):248. Unique Identifier : AIDSLINE MED/90325908
Routy JP; Blanc AP; Rodriguez E; Escoffier M; Joliot Y; Kiegel P; Viallet F; Chardon H
Risk of non-Hodgkin lymphoma and Kaposi's sarcoma in homosexual men [letter; comment]
Lancet. 1990 Jul 28;336(8709):248-9. Unique Identifier : AIDSLINE MED/90325909
Rabkin CS; Goedert JJ
Non-spastic paraparesis associated with HTLV-I [letter]
Lancet. 1990 Jul 28;336(8709):260. Unique Identifier : AIDSLINE MED/90325931
Kazadi K; Garin B; Goussard B; Salaun JJ; de-The G
Extracorporeal photopheresis in the treatment of AIDS-related complex: a pilot study [see comments]
Ann Intern Med. 1990 Aug 15;113(4):270-5. Unique Identifier : AIDSLINE MED/90328556
Bisaccia E; Berger C; Klainer AS; Morristown Memorial Hospital, New Jersey.
OBJECTIVE: To determine side effects of extracorporeal photopheresis in the treatment of patients with the acquired immunodeficiency syndrome (AIDS)-related complex, and to gain early evidence of efficacy of the treatment. DESIGN: Uncontrolled trial. SETTING: Tertiary referral center. PATIENTS: Five patients with AIDS


Development of non-Hodgkin lymphoma in a cohort of patients with severe human immunodeficiency virus (HIV) infection on long-term antiretroviral therapy.
Ann Intern Med. 1990 Aug 15;113(4):276-82. Unique Identifier : AIDSLINE MED/90328557
Pluda JM; Yarchoan R; Jaffe ES; Feuerstein IM; Solomon D; Steinberg SM; Wyvill KM; Raubitschek A; Katz D; Broder S; National Cancer Institute, National Institute of Neurological; Disorders and Stroke, Bethesda, Maryland.
OBJECTIVE: To describe the incidence of non-Hodgkin lymphoma in a group of patients with symptomatic human immunodeficiency virus (HIV) infection receiving long-term dideoxynucleoside antiretroviral therapy. DESIGN: We examined the records of all patients with the acquired immunodeficiency syndrome (AIDS) or severe AI


[AIDS and nursing. 1. European conference]
Krankenpfl Soins Infirm. 1990 Jun;83(6):29-30. Unique Identifier : AIDSLINE MED/90331443
Panchaud C
More international perspectives on HIV [news]
Lancet. 1990 Aug 4;336(8710):304-5. Unique Identifier : AIDSLINE MED/90331570
HTLV-I/II antibodies in UK blood donors [letter; comment]
Lancet. 1990 Aug 4;336(8710):317. Unique Identifier : AIDSLINE MED/90331592
Salker R; Tosswill JH; Barbara JA; Runganga J; Contreras M; Tedder RS; Parra-Mejia N; Mortimer PP
False-positive autoantibodies in HIV infection [letter; comment]
Lancet. 1990 Aug 4;336(8710):317-8. Unique Identifier : AIDSLINE MED/90331593
Davenport A; Grant PJ
Tracking AIDS epidemic in libraries [letter; comment]
Lancet. 1990 Aug 4;336(8710):318. Unique Identifier : AIDSLINE MED/90331594
Vandenbroucke JP
An alternative strategy for therapy of AIDS; a cure?
Med Hypotheses. 1990 Jun;32(2):157-8. Unique Identifier : AIDSLINE MED/90331791
Colaco CA; Quadrant Research Foundation, Cambridge Research Laboratories,; UK.
Present therapeutic strategies in AIDS require continuous treatment. The recognition of the major contribution of an autoimmune component to the pathology of the disease opens up the possibility of ablation of specific T-cell sets as a means of preventing and reversing the disease.


Pneumocystis carinii pneumonia in infants infected with the human immunodeficiency virus with more than 450 CD4 T lymphocytes per cubic millimeter.
N Engl J Med. 1990 Aug 23;323(8):531-3. Unique Identifier : AIDSLINE MED/90331963
Leibovitz E; Rigaud M; Pollack H; Lawrence R; Chandwani S; Krasinski K; Borkowsky W; Department of Pediatrics, New York University Medical Center, NY; 10016.
AIDS-related infections.
Sci Am. 1990 Aug;263(2):50-7. Unique Identifier : AIDSLINE MED/90333246
Mills J; Masur H; University of California School of Medicine, San Francisco.
Low incidence of HTLV infections in random blood donors with indeterminate western blot patterns.
Transfusion. 1990 Jul-Aug;30(6):491-4. Unique Identifier : AIDSLINE MED/90333477
Kwok S; Lipka JJ; McKinney N; Kellogg DE; Poiesz B; Foung SK; Sninsky JJ; Department of Infectious Diseases, Cetus Corporation, Emeryville,; California.
Peripheral blood mononuclear cells (PBMCs) were recovered from platelet units of 61 blood donors who were HTLV-I positive and 3 blood donors who were HTLV-I negative on enzyme-linked immunosorbent assay (ELISA). Western blot analyses were performed on the sera and DNA was prepared from the PBMCs and analyzed by the po


Autoantibodies against peripheral blood cells appear early in HIV infection and their prevalence increases with disease progression.
Clin Exp Immunol. 1990 Jul;81(1):11-7. Unique Identifier : AIDSLINE MED/90336116
Klaassen RJ; Mulder JW; Vlekke AB; Eeftinck Schattenkerk JK; Weigel HM; Lange JM; von dem Borne AE; Central Laboratory of The Netherlands Red Cross Blood Transfusion; Service, Amsterdam.
The presence of platelet- and neutrophil-bound immunoglobulin (PBIg and NBIg) in thrombocytopenic or neutropenic HIV-infected individuals has led to the concept that in HIV infection thrombocytopenia and neutropenia are mediated by autoimmunity. However, PBIg and NBIg were also demonstrated in non-cytopenic HIV-infect


Autoreactive cytotoxicity in HIV-infected individuals.
Clin Exp Immunol. 1990 Jul;81(1):18-24. Unique Identifier : AIDSLINE MED/90336128
Israel-Biet D; Venet A; Beldjord K; Andrieu JM; Even P; Laennec HIV Study Group, Hopital Laennec, Paris, France.
A possible role for autoimmunity in the pathogenesis of HIV infection has been suggested, based upon the certain degree of homology shared by HIV gp41 and MHC class II molecules. A number of humoral markers of autoimmunity have since been found in seropositive subjects. We have evaluated the cellular autoreactive resp


Impaired in vitro survival of monocytes from patients with HIV infection.
Clin Exp Immunol. 1990 Jul;81(1):25-30. Unique Identifier : AIDSLINE MED/90336129
Muller F; Rollag H; Gaudernack G; Froland SS; Institute of Bacteriology, University of Oslo, National Hospital,; Norway.
In vitro survival of monocytes (MO) was studied in 59 patients with HIV infection of different clinical stages. MO from 61 donors and 12 healthy seronegative homosexual men were also examined. Compared with the number of MO seeded, the percentage of adherent monocyte-derived macrophages (MDM) present after 10 days was


Surface immunoglobulin-positive T lymphocytes in HIV-1 infection: relationship to CD4+ lymphocyte depletion.
Clin Immunol Immunopathol. 1990 Aug;56(2):249-58. Unique Identifier : AIDSLINE MED/90336152
Ardman B; Mayer K; Bristol J; Ryan M; Settles M; Levy E; Department of Medicine, New England Medical Center Hospitals,; Boston, Massachusetts 02111.
T lymphocytes bound to autologous immunoglobulin (surface Ig + T cells) and serum antibodies that bind to allogeneic lymphocytes have been detected in HIV-1-infected individuals, but their significance in the immunopathogenesis of HIV-1 infection is uncertain. We tested peripheral blood from HIV-1-infected individuals


The natural course of HIV infections.
Pa Med. 1990 Jul;93(7):44-6. Unique Identifier : AIDSLINE MED/90340857
Pazin GJ
Hierarchical pattern of mucosal candida infections in HIV-seropositive women [see comments]
Am J Med. 1990 Aug;89(2):142-6. Unique Identifier : AIDSLINE MED/90342757
Imam N; Carpenter CC; Mayer KH; Fisher A; Stein M; Danforth SB; Brown University AIDS Program, Providence, Rhode Island.
PURPOSE: Candida is the most common cause of opportunistic mucosal infections in human immunodeficiency virus (HIV)-positive women. We had observed an apparent correlation between the severity of immunodeficiency and the site of mucosal candida infection. The current study was designed to determine whether significant


[The N-methyl-D-aspartate receptor complex. Various sites of regulation and clinical consequences]
Arzneimittelforschung. 1990 May;40(5):511-4. Unique Identifier : AIDSLINE MED/90343865
Turski L; Abteilung fur Neuropsychopharmakologie, Schering; Aktiengesellschaft, Berlin.
Amino acids such as L-glutamate und L-aspartate are major excitatory neurotransmitters in the mammalian central nervous system (CNS) and potential neurotoxins (excitotoxins), which can destroy central neurons by excessive activation of respective receptors. In the last three decades evidence has accumulated that excit


Policy protests, scientific spats take centre stage at Sixth International AIDS Conference.
Can Med Assoc J. 1990 Aug 15;143(4):312-5. Unique Identifier : AIDSLINE MED/90345365
Orkin A
Lymphocyte ectoenzyme activity compared in healthy persons and patients seropositive to or at high risk of HIV infection.
Immunol Cell Biol. 1990 Apr;68 ( Pt 2):81-5. Unique Identifier : AIDSLINE MED/90346413
Chalmers AH; Hare C; Woolley G; Frazer IH; Department of Pathology, Mater Misericordiae Public Hospital,; South Brisbane, Australia.
We measured two ectoenzymes, ecto-5 -nucleotidase (NT) and dipeptidyl peptidase IV (DP) in the peripheral blood lymphocytes of various groups of HIV-infected patients because of the previous implied relationship of these enzymes to immune function. NT expressed as mean nmol/h per mg protein (+/- s.d.) was significantl


A multicenter clinical trial of oral ribavirin in HIV-infected patients with lymphadenopathy. The Ribavirin-LAS Collaborative Group [published erratum appears in J Acquir Immune Defic Syndr 1991;4(4):450] [see comments]
J Acquir Immune Defic Syndr. 1990;3(9):884-92. Unique Identifier : AIDSLINE MED/90347672
Roberts RB; Dickinson GM; Heseltine PN; Leedom JM; Mansell PW; Rodriguez S; Johnson KM; Lubina JA; Makuch RW; New York Hospital-Cornell Medical Center, New York.
A double-blind, randomized, placebo-controlled trial comparing two daily doses of oral ribavirin and placebo was conducted at four medical centers. One hundred sixty-four adult men with lymphadenopathy were enrolled over a 2-month period and randomized to receive ribavirin 800 mg (53 subjects), ribavirin 600 mg (55 su


Modeling the decline of CD4+ T-lymphocyte counts in HIV-infected individuals [letter; comment]
J Acquir Immune Defic Syndr. 1990;3(9):930-1. Unique Identifier : AIDSLINE MED/90347682
Longini IM Jr
The National Cancer Institute phase I study of 2',3'-dideoxyinosine administration in adults with AIDS or AIDS-related complex: analysis of activity and toxicity profiles.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S522-33. Unique Identifier : AIDSLINE MED/90349973
Yarchoan R; Mitsuya H; Pluda JM; Marczyk KS; Thomas RV; Hartman NR; Brouwers P; Perno CF; Allain JP; Johns DG; et al; Clinical Oncology Program, National Cancer Institute, National; Institutes of Health, Bethesda, Maryland 20892.
2 ,3 -Dideoxyinosine (didanosine; ddI) was administered to 37 adults with AIDS or AIDS-related complex in an escalating-dose phase I study. Groups of three or four patients received intravenous dosages of 0.4 mg/(kg.d) to 25.6 mg/(kg.d) divided into two or three daily doses for 2 weeks, followed by oral ddI at twice t


Phase I study of 2',3'-dideoxyinosine: experience with 19 patients at New York University Medical Center.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S534-9. Unique Identifier : AIDSLINE MED/90349974
Valentine FT; Seidlin M; Hochster H; Laverty M; Department of Medicine, New York University Medical Center, New; York 10016.
We performed a phase I study of escalating dosages of 2 ,3 -dideoxyinosine (didanosine; ddI) in 19 patients with AIDS or AIDS-related complex in order (1) to establish the maximal tolerated dosage, (2) to determine the nature of toxic adverse effects, (3) to measure changes in levels of circulating human immunodeficie


2',3'-Dideoxyinosine in patients with AIDS or AIDS-related complex.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S540-9; discussion S549-51. Unique Identifier : AIDSLINE MED/90349975
Dolin R; Lambert JS; Morse GD; Reichman RC; Plank CS; Reid J; Knupp C; McLaren C; Pettinelli C; Department of Medicine, University of Rochester School of; Medicine and Dentistry, New York 14642.
Twenty-one patients with AIDS or AIDS-related complex (ARC) received 2 ,3 -dideoxyinosine (didanosine; ddI) intravenously and then orally (initial dosages of 0.4 mg/kg and 0.8 mg/kg every 12 hours, respectively) for 6-44 weeks in an escalating-dose study. The major dose-limiting effects were


Treatment of AIDS and AIDS-related complex with 2',3'-dideoxyinosine given once daily.
Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S552-60. Unique Identifier : AIDSLINE MED/90349976
Cooley TP; Kunches LM; Saunders CA; Perkins CJ; Kelley SL; McLaren C; McCaffrey RP; Liebman HA; Department of Medicine, Boston City Hospital, Boston University; School of Medicine, Massachusetts 02118.
In a phase I dosage-finding trial, 2 ,3 -dideoxyinosine (didanosine; ddI) was administered once daily to 36 patients with AIDS or AIDS-related complex for up to 65 weeks (mean, 32.1 weeks) at six dosage levels. Thirteen of 18 patients previously treated with zidovudine had developed hematologic intolerance. The maxima


Increasing viral burden in CD4+ T cells from patients with human immunodeficiency virus (HIV) infection reflects rapidly progressive immunosuppression and clinical disease.
Ann Intern Med. 1990 Sep 15;113(6):438-43. Unique Identifier : AIDSLINE MED/90351055
Schnittman SM; Greenhouse JJ; Psallidopoulos MC; Baseler M; Salzman NP; Fauci AS; Lane HC; National Institutes of Health, Bethesda, Maryland.
OBJECTIVE: To determine over time the relation between viral burden and immunologic decline in patients with asymptomatic human immunodeficiency virus (HIV) infection. DESIGN: Blind analysis of cell samples from matched cohorts for HIV proviral DNA by polymerase chain reaction, retrospective analysis of clinical data


Defective signal transduction--a common pathway for cellular dysfunction in HIV infection?
Immunol Today. 1990 Jul;11(7):256-9. Unique Identifier : AIDSLINE MED/90351547
Pinching AJ; Nye KE; Department of Immunology, St Mary's Hospital Medical School,; London, UK.
Qualitative defects in immune responsiveness after human immunodeficiency virus (HIV) infection have been well characterized and may play a key role in the development of HIV disease. However, no clear picture of the underlying mechanism of the functional deficiencies has yet emerged. In this article, Anthony Pinching


T-cell subset alterations and lymphocyte responsiveness to mitogens and antigen during severe primary infection with HIV: a case series of seven consecutive HIV seroconverters.
AIDS. 1990 Jun;4(6):523-6. Unique Identifier : AIDSLINE MED/90351565
Pedersen C; Dickmeiss E; Gaub J; Ryder LP; Platz P; Lindhardt BO; Lundgren JD; Department of Infectious Diseases, Hvidovre Hospital, University; of Copenhagen, Denmark.
Seven consecutive patients who presented with a severe acute mononucleosis-like illness associated with HIV seroconversion were evaluated by T-cell subset enumerations and measurements of lymphocyte transformation responses to mitogens and antigen during both their primary illness and a 1-year follow-up period. We obs


Productive infection of both CD4+ and CD4- human cell lines with HIV-1, HIV-2 and SIVagm.
AIDS. 1990 Jun;4(6):537-44. Unique Identifier : AIDSLINE MED/90351567
Werner A; Winskowsky G; Cichutek K; Norley SG; Kurth R; Paul-Ehrlich-Institut, Langen, FRG.
Human monolayer cells of various origins were shown to be susceptible to infection by HIV-1, HIV-2 and simian immunodeficiency virus obtained from African green monkeys (SIVagm). Immunoperoxidase staining revealed infection of 2-7% of the monolayer cells, although in order to achieve infection approximately 50-fold mo


Characterization of a putative cellular receptor for HIV-1 transmembrane glycoprotein using synthetic peptides.
AIDS. 1990 Jun;4(6):553-8. Unique Identifier : AIDSLINE MED/90351569
Qureshi NM; Coy DH; Garry RF; Henderson LA; Department of Pathology, Tulane Medical School, New Orleans,; Louisiana 70112.
The transmembrane glycoprotein (gp41 or TM) of HIV-1 contains limited sequence similarity to TM of some immunosuppressive animal retroviruses. A specific HIV-1 TM sequence, denoted CS3, inhibits T-cell activation in vitro and antibody specific to CS3 has been linked to the absence of disease. CS3, when conjugated to h


Interim proposal for a WHO Staging System for HIV infection and Disease.
Wkly Epidemiol Rec. 1990 Jul 20;65(29):221-4. Unique Identifier : AIDSLINE MED/90352128
Immunopathogenesis of human immunodeficiency virus infection.
Cancer Res. 1990 Sep 1;50(17 Suppl):5612S-5617S. Unique Identifier : AIDSLINE MED/90352612
Ioachim HL; Department of Pathology, Lenox Hill Hospital, Cornell University; Medical College, New York, NY 10021.
The acquired immunodeficiency syndrome (AIDS) is associated with a broad spectrum of opportunistic infections and neoplasias that differ from those occurring in the general population by their high aggressiveness, unusual location, early tendency to generalization, frequent relapse, and short survival. The severe comp


Changes in the level of soluble CD-2 molecules in the serum of HIV-infected individuals.
Cancer Detect Prev. 1990;14(3):347-51. Unique Identifier : AIDSLINE MED/90352637
Schlesinger M; Afik O; Loves O; Maayan S; Rabinowitz R; Hubert H. Humphrey Center for Experimental Medicine and Cancer; Research, Hebrew University-Hadassah Medical School, Jerusalem,; Israel.
It has been shown previously that the level of soluble CD-2 determinants (E-receptors) is elevated in the serum of patients with various immunodeficiency states. The aim of the present preliminary study was to determine the level of soluble CD-2 in the sera of individuals infected with human immunodeficiency virus (HI


Clinical implications of positive tests for antibodies to human immunodeficiency virus type 1 in asymptomatic blood donors.
Dis Markers. 1990 Mar-Apr;8(2):103-4. Unique Identifier : AIDSLINE MED/90352914
The reservoir for HIV-1 in human peripheral blood is a T cell that maintains expression of CD4.
Dis Markers. 1990 Mar-Apr;8(2):99-100. Unique Identifier : AIDSLINE MED/90352926
CD4+ T cells in murine acquired immunodeficiency syndrome: evidence for an intrinsic defect in the proliferative response to soluble antigen.
Eur J Immunol. 1990 Jul;20(7):1577-81. Unique Identifier : AIDSLINE MED/90353393
Cerny A; Hugin AW; Holmes KL; Morse HC 3d; Laboratory of Immunopathology, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.
C57BL/6 mice inoculated with LP-BM5 murine leukemia viruses develop an immunodeficiency syndrome, termed murine acquired immunodeficiency syndrome (MAIDS), characterized by a variety of functional abnormalities of T and B cells. In the present study, we have analyzed the ability of lymph node cells from infected mice


Expression of human adenosine deaminase in mice transplanted with hemopoietic stem cells infected with amphotropic retroviruses.
J Exp Med. 1990 Sep 1;172(3):729-36. Unique Identifier : AIDSLINE MED/90354774
van Beusechem VW; Kukler A; Einerhand MP; Bakx TA; van der Eb AJ; van Bekkum DW; Valerio D; Institute of Applied Radiobiology and Immunology-TNO, Rijswijk,; The Netherlands.
Amphotropic recombinant retroviruses were generated carrying sequences encoding human adenosine deaminase (ADA). Transcription of the human ADA gene was under control of a hybrid long terminal repeat in which the enhancer from the Moloney murine leukemia virus was replaced by an enhancer from the F101 host-range mutan


Doctors with HIV [news]
Lancet. 1990 Aug 18;336(8712):432. Unique Identifier : AIDSLINE MED/90355638
Outbreaks of drug-resistant tuberculosis at AIDS centre [letter]
Lancet. 1990 Aug 18;336(8712):440-1. Unique Identifier : AIDSLINE MED/90355648
Pitchenik AE; Burr J; Laufer M; Miller G; Cacciatore R; Bigler WJ; Witte JJ; Cleary T
Zidovudine with probenecid [letter; comment]
Lancet. 1990 Aug 18;336(8712):441. Unique Identifier : AIDSLINE MED/90355649
Duckworth AS; Duckworth GW; Henderson G; Contreras G
The trouble with T cells [letter; comment]
Lancet. 1990 Aug 25;336(8713):507. Unique Identifier : AIDSLINE MED/90355693
Ascher MS; Sheppard HW
Partner notification for HIV in Sweden [letter]
Lancet. 1990 Aug 25;336(8713):508. Unique Identifier : AIDSLINE MED/90355695
Giesecke J; Ramstedt K; Ripa T; Rado G; Scalia-Tomba G; Westrell M
Treating through hypersensitivity to cotrimoxazole in children with HIV infection [letter; comment]
Lancet. 1990 Aug 25;336(8713):508-9. Unique Identifier : AIDSLINE MED/90355696
Kreuz W; Gungor T; Lotz C; Funk M; Kornhuber B
Rapid progression to AIDS in dual HIV-1/HTLV-I infection [letter]
Lancet. 1990 Aug 25;336(8713):509. Unique Identifier : AIDSLINE MED/90355698
Lefrere JJ; Courouce AM; Mariotti M; Wattel E; Prou O; Bouchardeau F; Lambin P
Long-term toxicity/activity profile of 2',3'-dideoxyinosine in AIDS or AIDS-related complex [see comments]
Lancet. 1990 Sep 1;336(8714):526-9. Unique Identifier : AIDSLINE MED/90355719
Yarchoan R; Pluda JM; Thomas RV; Mitsuya H; Brouwers P; Wyvill KM; Hartman N; Johns DG; Broder S; Clinical Oncology Program, National Cancer Institute, Bethesda,; MD 20892.
To evaluate the long-term toxicity and activity profile of 2 ,3 -dideoxyinosine (ddI), a potent inhibitor of human immunodeficiency virus (HIV) replication, in vitro. 58 patients with AIDS or AIDS-related complex were studied with additional reference to the effect of previous treatment with zidovudine, and the effect


Life-threatening bacteraemia in HIV-1 seropositive adults admitted to hospital in Nairobi, Kenya [see comments]
Lancet. 1990 Sep 1;336(8714):545-9. Unique Identifier : AIDSLINE MED/90355728
Gilks CF; Brindle RJ; Otieno LS; Simani PM; Newnham RS; Bhatt SM; Lule GN; Okelo GB; Watkins WM; Waiyaki PG; et al; Clinical Research Centre, Kenya Medical Research Institute,; Nairobi.
During 6 months, 506 consecutive adult emergency admissions to hospital in Nairobi were enrolled in a study of bacteraemia and HIV infection. 19% were HIV-1 antibody positive. Significantly more HIV-seropositive than seronegative patients had bacteraemia (26% vs 6%). The predominant organisms isolated from the seropos


Fluconazole-induced jaundice [letter]
Lancet. 1990 Sep 1;336(8714):565. Unique Identifier : AIDSLINE MED/90355739
Franklin IM; Elias E; Hirsch C
Antibodies to Helicobacter pylori in HIV infection [letter; comment]
Lancet. 1990 Sep 1;336(8714):571. Unique Identifier : AIDSLINE MED/90355751
Aceti A; Celestino D; Pennica A; Leri O; Caferro M
Kaposi's sarcoma and HTLV-I infection [letter; comment]
Lancet. 1990 Sep 1;336(8714):575. Unique Identifier : AIDSLINE MED/90355757
Veyssier-Belot C; Couderc LJ; Desgranges C; Leblond V; Dairou F; Caubarrere I; de Gennes JL
HTLV-II infection in Italian drug abusers [letter]
Lancet. 1990 Sep 1;336(8714):575-6. Unique Identifier : AIDSLINE MED/90355759
Zella D; Mori L; Sala M; Ferrante P; Casoli C; Magnani G; Achilli G; Cattaneo E; Lori F; Bertazzoni U
Characterization of a new strain of HHV-6 (HHV-6SF) recovered from the saliva of an HIV-infected individual.
Virology. 1990 Sep;178(1):113-21. Unique Identifier : AIDSLINE MED/90357754
Levy JA; Ferro F; Lennette ET; Oshiro L; Poulin L; Cancer Research Institute, University of California, School of; Medicine, San Francisco 94143-0128.
An isolate of the human herpesvirus-6 (HHV-6SF) recovered from the saliva of an HIV-infected individual differs in its cellular host range and certain genomic properties from other HHV-6 strains described. HHV-6SF replicates in adult peripheral blood mononuclear cells (PMC) substantially better than in fetal cord bloo


Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases [published erratum appears in Eur J Biochem 1991 Aug 1;199(3):769]
Eur J Biochem. 1990 Jul 5;190(3):469-76. Unique Identifier : AIDSLINE MED/90322990
Ono K; Nakane H; Fukushima M; Chermann JC; Barre-Sinoussi F; Laboratory of Viral Oncology, Aichi Cancer Center Research; Institute, Nagoya, Japan.
Four flavonoids, 5,6,7-trihydroxyflavone (baicalein), 3,3 ,4 ,5,7-pentahydroxyflavone (quercetin), 3,3 ,4 ,5,6,7-hexahydroxyflavone (quercetagetin) and 3,3 ,4 ,5,5 ,7-hexahydroxyflavone (myricetin), were found to be potent inhibitors of reverse transcriptases from Rauscher murine leukemia virus (RLV) and human immunod


Analysis of nonproductive human immunodeficiency virus type 1 infection of human fetal dorsal root ganglia glial cells.
Intervirology. 1990;31(2-4):147-58. Unique Identifier : AIDSLINE MED/90324051
Kunsch C; Wigdahl B; Department of Microbiology and Immunology, Pennsylvania State; University College of Medicine, Hershey 17033.
Direct infection of glia by human immunodeficiency virus type 1 (HIV-1) has been suggested as one of several mechanisms responsible for the severe neurologic complications observed in both neonates and adults with the acquired immunodeficiency syndrome. We have demonstrated by protein immunoblotting analysis that HIV-


Determination of a unique and immunodominant epitope of human T cell lymphotropic virus type I.
J Infect Dis. 1990 Aug;162(2):353-7. Unique Identifier : AIDSLINE MED/90324645
Lipka JJ; Bui K; Reyes GR; Moeckli R; Wiktor SZ; Blattner WA; Murphy EL; Shaw GM; Hanson CV; Sninsky JJ; et al; Department of Pathology, Stanford University School of Medicine,; California.
The identification and isolation of unique and immunogenic recombinant epitopes for human T cell lymphotrophic virus (HTLV) type I might allow the development of an antibody-based assay to differentiate between HTLV-I and HTLV-II infections. To test the feasibility of this approach, an HTLV-I envelope epitope was isol


Synthesis and anti-HIV-1 activity of 2'-up-fluoro analogues of active anti-AIDS nucleosides 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (DDC).
J Med Chem. 1990 Aug;33(8):2145-50. Unique Identifier : AIDSLINE MED/90325205
Watanabe KA; Harada K; Zeidler J; Matulic-Adamic J; Takahashi K; Ren WY; Cheng LC; Fox JJ; Chou TC; Zhu QY; et al; Laboratory of Organic Chemistry, Memorial Sloan-Kettering Cancer; Center, New York, New York 10021.
1-(3-Azido-2,3-dideoxy-2-fluoro-beta-D-arabinofuranosyl)thymine (6, F- AZT ) and 1-(2,3-dideoxy-2-fluoro-beta-D-threopentofuranosyl)cytosine (12, F-DDC) were synthesized from the potent antiherpes virus nucleosides 1-(2-deoxy-2-fluoro-beta-D-arabinofura


Strength in numbers. Researchers begin combining compounds to fight AIDS [news]
Sci Am. 1990 Jul;263(1):20. Unique Identifier : AIDSLINE MED/90327036
Horgan J
Clinical use of biologic response modifiers in cancer treatment: an overview. Part I. The interferons.
DICP. 1990 Jul-Aug;24(7-8):761-8. Unique Identifier : AIDSLINE MED/90327812
Balmer CM; University of Colorado Cancer Center.
Interferons are proteins with antiviral, antiproliferative, and immune-regulating activity. They are classified as alfa, beta, or gamma on the basis of antigenicity and biologic properties. Alfa interferons as single-agent therapy produce clinical improvement in approximately 90 percent of patients with hairy-cell leu


HTLV-1-associated myelopathy (HAM) with OKT4 epitope deficiency [letter] [published erratum appears in Acta Neurol Scand 1990 Oct;82(4):287]
Acta Neurol Scand. 1990 May;81(5):475. Unique Identifier : AIDSLINE MED/90328011
Kishimoto M; Araga S; Adachi Y; Takahashi K
The response of symptomatic gastrointestinal Kaposi's sarcoma to chemotherapy: a prospective evaluation using an endoscopic method of disease quantification.
Am J Gastroenterol. 1990 Aug;85(8):959-61. Unique Identifier : AIDSLINE MED/90328165
Laine L; Amerian J; Rarick M; Harb M; Gill PS; Department of Medicine, University of Southern California School; of Medicine, Los Angeles.
We used an endoscopic method of quantification to evaluate the response of symptomatic gastrointestinal Kaposi s sarcoma (KS) prospectively in seven patients with acquired immune deficiency syndrome (AIDS) who were participating in chemotherapy trials for extensive cutaneous KS. The sums of the diameters of KS lesions


[Comparative inhibitory analysis of DNA biosynthesis catalyzed by retrovirus reverse transcriptase]
Bioorg Khim. 1990 Apr;16(4):531-6. Unique Identifier : AIDSLINE MED/90329043
Kileso TIu; Tarusova NB; Atrazheva ED; Kukhanova MK; Shulenin SV; Bobkov AF; Garaev MM; Galegov GA; Kraevskii AA
Comparative study of DNA biosynthesis inhibition, catalyzed by avian myeloblastose virus (AMV) reverse transcriptase (RT), human immunodeficiency virus (HIV) recombinant and native RT, has been performed. 3 -Azido-2 ,3 -dideoxythymidine 5 -triphosphate (AzTTP); 3 -azido-2 ,3 -dideoxythymidine 5 -methylenephosphonate-d


A putative approach for gene therapy against human immunodeficiency virus (HIV).
Med Hypotheses. 1990 Jun;32(2):81-4. Unique Identifier : AIDSLINE MED/90331793
Faraji-Shadan F; Stubbs JD; Bowman PD; Department of Biology, San Francisco State University, CA 94132.
It is proposed here that a form of intracellular immunity can be devised which would protect cells from virus infection and, in particular, could be used as a treatment for the human immunodeficiency virus (HIV) infected individual. Following in vitro immunization of naive human B lymphocytes with reverse-transcriptas


RNA transcripts of the human immunodeficiency virus transactivation response element can inhibit action of the viral transactivator.
Proc Natl Acad Sci U S A. 1990 Aug;87(15):5817-21. Unique Identifier : AIDSLINE MED/90332673
Graham GJ; Maio JJ; Department of Cell Biology, Albert Einstein College of Medicine,; Bronx, NY 10461.
Tandem repeats of the transactivation response element (TAR) of the human immunodeficiency virus 1 (HIV-1) were generated using a specially constructed tandemizing plasmid, pGem-Tan. This plasmid exploits the rotational nonequivalence of Ava I restriction sites to generate multiple copies of an inserted sequence. Twel


Treatment of advanced Kaposi's sarcoma using a combination of bleomycin and vincristine.
Am J Clin Oncol. 1990 Aug;13(4):315-9. Unique Identifier : AIDSLINE MED/90334090
Gill P; Rarick M; Bernstein-Singer M; Harb M; Espina BM; Shaw V; Levine A; Department of Internal Medicine, University of Southern; California School of Medicine.
Eighteen patients with disseminated AIDS-related Kaposi s sarcoma (KS) and compromised bone marrow function were treated with a relatively non-myelosuppressive regimen of bleomycin and vincristine (BV). At study entry, the patients presented with the following median laboratory values: hemoglobin of 9.5 g/dl, granuloc


Working group on AIDS case definition.
Epidemiol Bull. 1990;10(4):9-11. Unique Identifier : AIDSLINE MED/90335024
Human T-lymphotropic virus type I transcriptional regulation by methylation.
Cancer Res. 1990 Aug 15;50(16):4968-73. Unique Identifier : AIDSLINE MED/90335797
Saggioro D; Panozzo M; Chieco-Bianchi L; Department of Biotechnology, University of Padova, Italy.
While human T-lymphotropic virus type I (HTLV-I) proviral genome is readily detected in leukemic lymphocytes from adult T-cell leukemia patients, viral antigens or viral RNA are not expressed unless these cells are cultured. To address the problem of possible restriction mechanism of HTLV-I replication, we studied the


Cloned stromal cell lines derived from human Whitlock/Witte-type long-term bone marrow cultures.
Exp Hematol. 1990 Aug;18(7):775-84. Unique Identifier : AIDSLINE MED/90336701
Novotny JR; Duehrsen U; Welch K; Layton JE; Cebon JS; Boyd AW; Lions Clinical Cancer Research Laboratory, Walter and Eliza Hall; Institute of Medical Research, PO Royal Melbourne Hospital,; Australia.
We report a human bone marrow culture technique that initially parallels the murine Whitlock/Witte culture system. As in the murine system, B cells predominate over other cell types, and all differentiation stages from pre-B to plasma cell are observed. Although these human long-term cultures pass through stages resem


Heat shock induction of HIV production from chronically infected promonocytic and T cell lines.
J Immunol. 1990 Aug 15;145(4):1120-6. Unique Identifier : AIDSLINE MED/90338743
Stanley SK; Bressler PB; Poli G; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.
HIV infection is associated with a long period of clinical latency before the development of symptoms and HIV-related disease. Two chronically HIV-infected cell lines, U1 (promonocytic) and ACH-2 (T-lymphocytic) have been developed as models for studying the mechanisms governing viral latency and the reactivation of v


Study of long-term cultures of simian immunodeficiency virus (SIVmac 251)-infected peripheral blood lymphocytes.
Lab Invest. 1990 Aug;63(2):242-7. Unique Identifier : AIDSLINE MED/90339797
Montaner LJ; Ringler DJ; Wyand MS; Mattmuller MR; MacKey JJ; Schmidt DK; Daniel MD; King NW; Department of Pathology, Kansas State University, College of; Veterinary Medicine, Manhattan.
A culture of rhesus monkey peripheral blood lymphocytes was divided into two parts; one was kept as an uninfected control, and the other was infected with a strain of simian immunodeficiency virus (SIVmac251) originally isolated from a rhesus monkey that died of a malignant lymphoma associated with acquired immune def


Confronting the hypervariability of an immunodominant epitope eliciting virus neutralizing antibodies from the envelope glycoprotein of the human immunodeficiency virus type 1 (HIV-1).
Mol Immunol. 1990 Jun;27(6):539-49. Unique Identifier : AIDSLINE MED/90340321
Neurath AR; Strick N; Lindsley F. Kimball Research Institute, New York Blood Center, NY; 10021.
Antibody mediated and cell mediated immune responses to the envelope glycoproteins gp120 and gp41 of the human immunodeficiency virus (HIV-1) are considered important for protection against infection and for attenuation of disease symptoms after infection. Virus neutralizing antibodies are mostly subtype specific and


Flow cytometric method to monitor the destruction of CD4+ cells following their fusion with HIV-infected cells.
Cytometry. 1990;11(6):736-43. Unique Identifier : AIDSLINE MED/90345763
Schols D; Pauwels R; Desmyter J; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.
Syncytium formation between HUT-78 cells persistently infected with human immunodeficiency virus type 1 (HIV-1) and uninfected CD4-bearing MOLT-4 or CEM cells results in a rapid destruction of the MOLT-4 or CEM cells. This syncytium formation is due to the interaction between the gp120 glycoprotein expressed by the pe


Novel features of retroviruses associated with human diseases.
FEBS Lett. 1990 Aug 1;268(2):415-21. Unique Identifier : AIDSLINE MED/90346204
Chandra P; Gerber T; Chandra A; Laboratory of Molecular Biology, (ZBC), University Medical; School, Frankfurt, FRG.
The last decade has witnessed a new chapter in the history of retrovirology. As of now, four human retroviruses have been identified and molecularly characterized. They are associated with a wide spectrum of human diseases including cancer, immunodeficiency and neurological disorders. By virtue of their clinical relev


Unintegrated DNA in cells infected in vitro with human immunodeficiency virus (HIV): a new approach to suppression of virus release.
J Virol Methods. 1990 Jun;28(3):219-33. Unique Identifier : AIDSLINE MED/90347021
Masuda T; Harada S; Department of Biodefence and Medical Virology, Kumamoto; University Medical School, Japan.
Retroviral RNA is copied into DNA by reverse transcriptase when the viral genome enters into its life cycle. In the case of human immunodeficiency virus (HIV), massive amounts of unintegrated viral DNA reportedly appear in the early phase of primary infection. However, the relationship between the accumulation of this


Export and one-step purification from Escherichia coli of a MalE-CD4 hybrid protein that neutralizes HIV in vitro.
J Acquir Immune Defic Syndr. 1990;3(9):859-72. Unique Identifier : AIDSLINE MED/90347669
Szmelcman S; Clement JM; Jehanno M; Schwartz O; Montagnier L; Hofnung M; Programmation Moleculaire and Toxicologie Genetique, Institut; Pasteur, Paris, France.
The 177 N-terminal amino acids of CD4, the receptor of the human immunodeficiency virus (HIV), have been expressed in Escherichia coli as genetic fusions to the periplasmic maltose-binding protein (MalE) from this organism. A large fraction of the hybrid proteins can be released from the periplasm by osmotic shock and


Altered mouse mammary tumor virus transcript synthesis in T-cell lymphoma cells.
J Virol. 1990 Sep;64(9):4043-50. Unique Identifier : AIDSLINE GENBANK/M55697
Racevskis J; Department of Oncology, Montefiore Medical Center, Bronx, New; York.
Proviral copies of mouse mammary tumor virus (MMTV) are known to be amplified in certain T-cell lymphomas. Transcription of the amplified MMTV proviruses was studied in detail in two T-cell lymphoma lines and showed the production of deletions and premature termination of env mRNAs and the premature termination of gag


Analysis of a highly immunodominant epitope in the human immunodeficiency virus type 1 transmembrane glycoprotein, gp41, defined by a human monoclonal antibody.
J Virol. 1990 Sep;64(9):4123-9. Unique Identifier : AIDSLINE MED/90347803
Bugge TH; Lindhardt BO; Hansen LL; Kusk P; Hulgaard E; Holmback K; Klasse PJ; Zeuthen J; Ulrich K; Laboratory of Tumor Virology, Fibiger Institute, Danish Cancer; Society, Copenhagen.
A human monoclonal antibody, 41-7 [immunoglobulin G1(kappa)], directed against the transmembrane glycoprotein gp41 of the human immunodeficiency virus type 1 (HIV-1) has been produced by direct fusion of lymph node cells from an HIV-1-infected individual with a human B-lymphoblastoid cell line. The minimal essential e


Linear B-cell epitopes of the major core protein of human immunodeficiency virus types 1 and 2 [published erratum appears in J Virol 1992 Jan;66(1):613]
J Virol. 1990 Sep;64(9):4258-63. Unique Identifier : AIDSLINE MED/90347819
Janvier B; Archinard P; Mandrand B; Goudeau A; Barin F; Departement de Microbiologie Medicale et Moleculaire, URA CNRS; 1334, CHRU Bretonneau, Tours, France.
Nine murine monoclonal antibodies directed to the major core protein p24 of human immunodeficiency virus type 1 (HIV-1) were obtained and then tested by using an epitope mapping system (Pepscan) covering the whole p24HIV1 protein to characterize antigenic domains. Four different linear epitopes were identified. Monocl


Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo.
Nature. 1990 Aug 16;346(6285):629-33. Unique Identifier : AIDSLINE MED/90348962
Pircher H; Moskophidis D; Rohrer U; Burki K; Hengartner H; Zinkernagel RM; Institute of Pathology, University Hospital, Zurich, Switzerland.
Viruses persist in an immune population, as in the case of influenza, or in an individual, as postulated for human immunodeficiency virus, when they are able to escape existent neutralizing antibody responses by changing their antigens. It is now shown that viruses can in principle escape the immunosurveillance of vir


Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope protein.
Proc Natl Acad Sci U S A. 1990 Aug;87(16):6136-40. Unique Identifier : AIDSLINE MED/90349569
Abrignani S; Montagna D; Jeannet M; Wintsch J; Haigwood NL; Shuster JR; Steimer KS; Cruchaud A; Staehelin T; Department of Allergy/Immunology, CIBA-Geigy Ltd., Basel,; Switzerland.
A nonglycosylated denatured form of human immunodeficiency virus (HIV) 1 glycoprotein gp120 (Env 2-3), which does not bind to CD4, was used with muramyl tripeptide as adjuvant to immunize HIV-seronegative healthy volunteers. In all the volunteers, three 50-micrograms injections of Env 2-3 induced priming of CD4+ T cel


Perceived effectiveness of fear appeals in AIDS education: relationship to ethnicity, gender, age, and group membership.
AIDS Educ Prev. 1990 Spring;2(1):1-11. Unique Identifier : AIDSLINE MED/90351742
Rhodes F; Wolitski RJ; Psychology Department, California State University, Long Beach; 90840.
A study was conducted with 261 community residents, college students, and intravenous drug users to investigate perceived effectiveness of fear appeals in AIDS education posters. Experimental posters with high-fear pictures portraying severe consequences of AIDS and low-fear posters that were neutral regarding disease


T activation marker evaluation in ARC patients treated with AZT. Comparison with CD4+ lymphocyte count in non-progressors and progressors towards AIDS.
Clin Exp Immunol. 1990 Aug;81(2):177-82. Unique Identifier : AIDSLINE MED/90352851
Levacher M; Tallet S; Dazza MC; Dournon E; Rouveix B; Pocidalo JJ; Pharmacology Laboratory, INSERM U13, Hopital Claude Bernard,; Paris, France.
Reductions in the percentage and absolute number of CD4+ lymphocytes, as well as abnormally high levels of activated peripheral T lymphocytes (CD3+ HLA-DR+ phenotype) and an increased proportion of CD8+ cells coexpressing the CD57 surface antigen (involved in natural killer activity) have been reported in HIV infectio


Effect of phorbol myristate acetate on T cell colony formation, interleukin-2 (IL-2) receptor expression and IL-2 production by cells from patients at all stages of HIV infection.
Clin Exp Immunol. 1990 Aug;81(2):200-6. Unique Identifier : AIDSLINE MED/90352855
Allouche M; Lunardi-Iskandar Y; Varela-Millot C; Itzhaki M; Cornuet P; Meyer P; Jasmin C; Georgoulias V; Unite d'Oncogenese Appliquee, Hopital Paul Brousse,; Villejuif, France.
We and others have shown that several T cell responses induced by the mitogen phytohaemagglutinin (PHA), including T cell colony formation, IL-2 receptor (IL-2R) expression, and IL-2 production are impaired in patients with AIDS and lymphadenopathy syndrome (LAS). We i


Human immunodeficiency virus 1: predominance of a group-specific neutralizing epitope that persists despite genetic variation.
Dis Markers. 1990 Mar-Apr;8(2):105-7. Unique Identifier : AIDSLINE MED/90352916
Rapid diagnosis of Pneumocystis carinii infection in AIDS by cytocentrifugation and rapid hematoxylin-eosin staining.
Diagn Cytopathol. 1990;6(3):164-8. Unique Identifier : AIDSLINE MED/90353074
Strigle SM; Gal AA; Koss MN; Department of Pathology and Laboratory Medicine, Los Angeles; County-University of Southern California Medical Center 90033.
Pneumocystis carinii pneumonia (PCP) is the major pulmonary complication in patients with the acquired immunodeficiency syndrome. While fiberoptic bronchoscopy with bronchoalveolar lavage (BAL) and transbronchial biopsy (TBBX) is regarded as the procedure of choice to identify PCP, these techniques, particularly TBBX,


The inhibition of human immunodeficiency virus type 1 reverse transcriptase by avarol and avarone derivatives.
FEBS Lett. 1990 Aug 20;269(1):131-4. Unique Identifier : AIDSLINE MED/90353554
Loya S; Hizi A; Department of Cell Biology and Histology, Sackler School of; Medicine, Tel-Aviv University, Israel.
We have analyzed the effects of several natural compounds related to avarols and avarones on the catalytic functions of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). The most potent substances, designated as avarone A,B and E and avarol F, inhibited indiscriminately the enzymatic activities o


Immunological crossreactivity between the human immunodeficiency virus type 1 virion infectivity factor and a 170-kD surface antigen of Schistosoma mansoni.
J Exp Med. 1990 Sep 1;172(3):1001-4. Unique Identifier : AIDSLINE MED/90354765
Khalife J; Grzych JM; Pierce R; Ameisen JC; Schacht AM; Gras-Masse H; Tartar A; Lecocq JP; Capron A; Centre d'Immunologie et de Biologie Parasitaire, Unite Mixte; INSERM, U167-CNRS 624, Strasbourg, France.
A monoclonal antibody (mAb) directed against a synthetic peptide derived from the sequence of the human immunodeficiency virus type 1 (HIV-1) regulatory protein virion infectivity factor (vif) labeled the surface of Schistosoma mansoni schistosomula by indirect immunofluorescence. Western blotting showed that two S. m


Variants selected by treatment of human immunodeficiency virus-infected cells with an immunotoxin.
J Exp Med. 1990 Sep 1;172(3):745-57. Unique Identifier : AIDSLINE MED/90354776
Pincus SH; Wehrly K; Tschachler E; Hayes SF; Buller RS; Reitz M; Laboratory of Microbial Structure and Function, National; Institute of Allergy and Infectious diseases, Hamilton, Montana; 59840.
An immunotoxin has been made by coupling anti-human immunodeficiency virus (HIV) envelope antibody 907 to ricin A chain (907-RAC). 907 recognizes an epitope within the immunodominant PB-1 loop of gp120. Variant cells were selected by cloning persistently infected H9/human T lymphocyte virus IIIB cells in the presence


HIV-1 testing: product development strategies.
Trends Biotechnol. 1990 Feb;8(2):35-40. Unique Identifier : AIDSLINE MED/90321521
Gottfried TD; Urnovitz HB; Calypte Biomedical Corporation, Berkeley, CA 94710.
Strategies for the development of diagnostic products for acquired immune deficiency syndrome (AIDS) are inextricably linked to the status of our knowledg