ETIOLOGY OF CANCER IN MAN NLM AIDSLINE Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

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ETIOLOGY OF CANCER IN MAN

Cancer Growth Prog; 6:1-233 1989. Unique Identifier : AIDSLINE ICDB/90660455
Anonymous; No affiliation given

Abstract: There are many causes for the appearance of neoplastic diseases. These diseases show a distinct relationship to a variety of environmental stimuli and to non-neoplastic diseases. Left untreated, cancer's development, as seen in populations lacking access to state-of-the-art health care, differs from that seen in patients (pts) undergoing treatment for these diseases. With these factors in mind, current knowledge concerning cancer growth and progression is reviewed as it relates to the etiology of human cancer. Topics include neoplastic diseases as multistep maladies; relationships between malignant and nonmalignant diseases in pts in Western countries; genetic diseases, hamartomas, and familial occurrence of neoplasms; genetic evaluation of ontologically related neural crest tumors; comparison of multiple primary neoplasms between pts in Japan and the United States; selected aspects of primary liver carcinoma in pts in Japan; effects of localized and disseminated cancers on metabolism and nutrition in man; the natural untreated course of breast cancer; hormone-dependent breast cancer; prolactin and estrogen in mammary tumorigenesis; assessment of the endocrine risk of developing breast cancer; appearance of neoplasms during pregnancy; urbanization parameters as moderators of the connection between background radiation and leukemia (single variable and multifactor models); radiation therapy-induced neoplasms; chemotherapy-induced neoplasms, side effects, and drug carcinogenicity; malignant neoplasms in organ transplant recipients; neoplastic progression induced by asbestos (mesothelioma); the immune reaction in oncogenesis as a host-tumor interaction; the AIDS epidemic and neoplasms; the atherosclerotic plaque as tumor or scar; neoplasms induced by noncancer therapies; observations of primary and secondary lesions in the same pt; and computer simulation of the heterogeneity of tumor behavior.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS Human Neoplasms/*ETIOLOGY Occupational Diseases/ETIOLOGY Risk Factors MONOGRAPHKWDacquiredimmunodeficiencysyndrome/complicationshumanneoplasms/KWDetiologyoccupationaldiseases/etiologyriskfactorsmonograph
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M9051015

Copyright © 1990 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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