Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.
RETROVIRUSES
Eighteenth Meeting of the European Tumor Virus Group. April 30-May 4, 1989, Sundbyholm's Castle, Sweden, Swedish Cancer Society, 1989.. Unique Identifier : AIDSLINE ICDB/90660587 Anonymous; No affiliation given
Abstract:
Abstracts are presented for the 18th European Tumor Virus Group meeting held April 30-May 4, 1989, in Sweden. Titles for the portion of the meeting covering retroviruses include a murine leukemia virus (MuLV) transmission vector system designed to analyze the integration pattern of retroviruses and their potential activation of oncogenes; the phenotype of rat T-cell lymphomas induced by Moloney murine leukemia virus (MoMuLV: several stages of T-cell development); paralysis induced in mice by a MuLV; bovine leukemia virus (BLV) transcription (development of an in vitro system); infection of adult rats with BLV (establishment of a rat BLV-producing cell line); simian T-lymphotropic virus-I-associated T- and B-cell baboon malignant lymphoma (direct or indirect role for retrovirus in lymphomagenesis); determination of human T-lymphotropic virus (HTLV)-I infection in patients with different blood pathologies; association of HTLV-I with various forms of hemoblastoses; improved assays for DNA-polymerizing enzymes using enzymatically synthesized 5-125I-iododeoxyuridine triphosphate (direct quantitation of anti-HIV-RT antibody); salivary antibodies to HIV in patients with, or at risk for, AIDS; enhancement of retrovirus-induced cell fusion by proteases; effect of heat-shock on HIV-1 replication cycle; regulation of HTLV-I expression in an infected cell line by methylation; effect of avian erythroblastosis virus on the cell-mediated immunity of chickens and turkeys; association of provirus insertion in a novel locus of common integration (tpl-1) with tumor progression in MoMuLV-induced thymic lymphomas; BLV-packaging cell line for retroviral-mediated gene transfer; sequence and antigenic drift of the BLV env glycoproteins and their inference on a three-dimensional model; a single-tube, one-step purification and assay system for the analysis of reverse transcriptase activity in crude specimens and some applications with reference to HIV; and human receptors for retroviruses.
Keywords: Animal Cell Line, Transformed Cell Transformation, Neoplastic/*GENETICS Cell Transformation, Viral/*GENETICS Gene Expression Regulation, Viral/PHYSIOLOGY Genes, Viral/PHYSIOLOGY Human HIV/GENETICS HTLV-I/GENETICS Retroviridae/*GENETICS MONOGRAPH 900530
M9051012
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