Oral Kaposi's sarcoma in acquired immunodeficiency syndrome. Review of management and report of the efficacy of intralesional vinblastine. NLM AIDSLINE Important note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

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Oral Kaposi's sarcoma in acquired immunodeficiency syndrome. Review of management and report of the efficacy of intralesional vinblastine.

Cancer. 1989 Dec 15;64(12):2424-30. Unique Identifier : AIDSLINE MED/90058398
Epstein JB; Lozada-Nur F; McLeod WA; Spinelli J; Cancer Control Agency of British Columbia, Vancouver, Canada.

Abstract: Treatment of palatal Kaposi's sarcoma (KS) with intralesional injection of vinblastine was seen to provide effective palliation. Of the ten patients studied, four had a 25% to 50% response, two 50% to 75% response, and four had 75% to 100% response with one or two intralesional injections of vinblastine. Response to treatment was followed for a mean of 3.6 months, with recurrence of lesions in two of ten patients.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Human Injections, Intralesional Male Middle Age Mouth Neoplasms/*DRUG THERAPY/PATHOLOGY Palatal Neoplasms/*DRUG THERAPY/PATHOLOGY Sarcoma, Kaposi's/*DRUG THERAPY/PATHOLOGY Vinblastine/ADMINISTRATION & DOSAGE/*THERAPEUTIC USE JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadulthumaninjections,intralesionalmalemiddleagemouthneoplasms/KWDdrugtherapy/pathologypalatalneoplasms/KWDdrugtherapy/pathologysarcoma,kaposi's/KWDdrugtherapy/pathologyvinblastine/administration&dosage/KWDtherapeuticusejournalarticle
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M9030669

Copyright © 1990 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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